ibuprofen and pentoxifylline

ibuprofen has been researched along with pentoxifylline in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (43.48)18.2507
2000's7 (30.43)29.6817
2010's5 (21.74)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Cunnion, RE; Martich, GD; Parker, MM; Suffredini, AF1
Ceska, M; Danner, RL; Martich, GD; Suffredini, AF1
Adi, S; Feingold, KR; Fiers, W; Grunfeld, C; Moser, A; Soued, M1
Blandino, G; Cook, JA; Cusumano, V; Mancuso, G; Smith, E; Squadrito, F; Teti, G1
Cai, B; Greenberg, S; Hyman, A; Kolls, J; Lippton, H; Nelson, S; Summer, WR; Wang, Y; Xie, J1
Santos, AA; Wilmore, DW1
Konstan, MW1
Dadan, J; Dzienis, H; Ladny, JR; Polaków, J; Puchalski, Z; Venskutonis, D1
Avitsur, R; Weidenfeld, J; Yirmiya, R1
De la Roche, CA; Escobar, CE; Falabella, R; Sanclemente, G1
Golubeva, AV; Grinëv, MV1
Chu, SJ; Feng, NH; Lin, HI; Wang, D1
Bilgiç, S; Ozenç, S; Ozkan, H; Safaz, I; Yildiz, C1
Glushchenko, VA; Karitsky, AP; Kvashnin, AV; Rozengard, SA; Ryazankina, AA1

Reviews

3 review(s) available for ibuprofen and pentoxifylline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Treatment of airway inflammation in cystic fibrosis.
    Current opinion in pulmonary medicine, 1996, Volume: 2, Issue:6

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Age Factors; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Chemotaxis, Leukocyte; Child; Cystic Fibrosis; Disease Progression; Fish Oils; Glucocorticoids; Humans; Ibuprofen; Inflammation; Leukocyte Elastase; Neutrophils; Pentoxifylline; Phosphodiesterase Inhibitors; Piroxicam; Pneumonia; Prednisone; Protease Inhibitors; Quality of Life

1996
[Multiple organ failure].
    Vestnik khirurgii imeni I. I. Grekova, 2001, Volume: 160, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Controlled Clinical Trials as Topic; Cyclooxygenase Inhibitors; Hemofiltration; Humans; Ibuprofen; Multicenter Studies as Topic; Multiple Organ Failure; Pentoxifylline; Phosphodiesterase Inhibitors; Plasmapheresis; Prognosis; Risk Factors; Sepsis; Ultrafiltration; Wounds and Injuries

2001

Trials

4 trial(s) available for ibuprofen and pentoxifylline

ArticleYear
Effects of ibuprofen and pentoxifylline on the cardiovascular response of normal humans to endotoxin.
    Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 73, Issue:3

    Topics: Adult; Cardiovascular Physiological Phenomena; Cardiovascular System; Endotoxins; Female; Hemodynamics; Humans; Ibuprofen; Male; Oxygen Consumption; Pentoxifylline; Shock, Septic; Tumor Necrosis Factor-alpha; Ventricular Function, Left

1992
Detection of interleukin 8 and tumor necrosis factor in normal humans after intravenous endotoxin: the effect of antiinflammatory agents.
    The Journal of experimental medicine, 1991, Apr-01, Volume: 173, Issue:4

    Topics: Adult; Endotoxins; Escherichia coli; Female; Fever; Humans; Ibuprofen; Injections, Intravenous; Interleukin-6; Interleukin-8; Male; Pentoxifylline; Time Factors; Tumor Necrosis Factor-alpha

1991
The systemic inflammatory response: perspective of human endotoxemia.
    Shock (Augusta, Ga.), 1996, Volume: 6 Suppl 1

    Topics: Body Temperature; Cytokines; Endotoxemia; Endotoxins; Escherichia coli Infections; Heart Rate; Humans; Hydrocortisone; Ibuprofen; Leukocyte Count; Lymphocyte Activation; Neutrophils; Pentoxifylline; Platelet Count; Superoxides; Systemic Inflammatory Response Syndrome

1996
[Optimization of pharmacological therapy for weakness syndrome in incurable patients].
    Voprosy onkologii, 2015, Volume: 61, Issue:2

    Topics: Acetamides; Adamantane; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Antineoplastic Agents; Dexamethasone; Dopamine; Drug Therapy, Combination; Fatigue; Female; Humans; Hypnotics and Sedatives; Ibuprofen; Male; Middle Aged; Muscle Weakness; Neoplasms; Ondansetron; Pentoxifylline; Radiation-Protective Agents; Serotonin; Serotonin Antagonists; Syndrome; Treatment Outcome

2015

Other Studies

16 other study(ies) available for ibuprofen and pentoxifylline

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Search for mediators of the lipogenic effects of tumor necrosis factor: potential role for interleukin 6.
    Cancer research, 1990, Jul-15, Volume: 50, Issue:14

    Topics: Animals; Aspirin; Azepines; Cholesterol; Fatty Acids; Ibuprofen; Interleukin-6; Lipids; Liver; Male; Mice; Mice, Inbred C57BL; Oleic Acid; Oleic Acids; Pentoxifylline; Phenoxybenzamine; Platelet Activating Factor; Propranolol; Rats; Rats, Inbred Strains; Reference Values; Triazoles; Triglycerides; Tumor Necrosis Factor-alpha

1990
Efficacy of tumor necrosis factor alpha and eicosanoid inhibitors in experimental models of neonatal sepsis.
    FEMS immunology and medical microbiology, 1994, Volume: 9, Issue:1

    Topics: Acetophenones; Animals; Animals, Newborn; Bacterial Toxins; Chromonar; Eicosanoids; Endotoxins; Ibuprofen; Pentoxifylline; Rats; Rats, Sprague-Dawley; Sepsis; Streptococcal Infections; Streptococcus agalactiae; Tetrazoles; Tumor Necrosis Factor-alpha

1994
Tumor necrosis factor-alpha inhibits endothelium-dependent relaxation.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 74, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arginine; Cattle; Endothelium, Vascular; Histamine; Ibuprofen; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Pentoxifylline; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Pulmonary Veins; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents

1993
[The effect of some drugs on the levels of selected cytokines in experimental septic shock].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1997, Volume: 50 Suppl 1 Pt 2

    Topics: Animals; Anti-Inflammatory Agents; Cytokines; Dexamethasone; Disease Models, Animal; Ibuprofen; Liver; Lung; Male; Mice; Pentoxifylline; Shock, Septic; Spleen; Survival Rate

1997
Cytokines inhibit sexual behavior in female rats: II. Prostaglandins mediate the suppressive effects of interleukin-1beta.
    Brain, behavior, and immunity, 1999, Volume: 13, Issue:1

    Topics: Animals; Corticosterone; Cyclooxygenase Inhibitors; Cytokines; Depression, Chemical; Female; Hypothalamus; Ibuprofen; Indomethacin; Injections, Intraventricular; Interleukin-1; Male; Pentoxifylline; Posture; Prostaglandins; Rats; Rats, Inbred F344; Sexual Behavior, Animal; Vasodilator Agents

1999
Pentoxyfylline in toxic epidermal necrolysis and Stevens-Johnson syndrome.
    International journal of dermatology, 1999, Volume: 38, Issue:11

    Topics: Child, Preschool; Drug Eruptions; Female; Humans; Ibuprofen; Male; Pentoxifylline; Stevens-Johnson Syndrome

1999
Pharmacological modulation of TNF production in macrophages.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2004, Volume: 37, Issue:1

    Topics: Animals; Benzoquinones; Cell Line; Cyclooxygenase Inhibitors; Ibuprofen; Indomethacin; Lipopolysaccharides; Lipoxygenase Inhibitors; Macrophage Activation; Macrophages; Mice; Pentoxifylline; Tumor Necrosis Factor-alpha

2004
Treating frostbite.
    Canadian family physician Medecin de famille canadien, 2008, Volume: 54, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibiotic Prophylaxis; Anticoagulants; Aspirin; Bencyclane; Clinical Protocols; Dextrans; Frostbite; Humans; Ibuprofen; Male; Military Personnel; Pentoxifylline; Platelet Aggregation Inhibitors; Rewarming; Vasodilator Agents

2008