ibuprofen and paclitaxel

ibuprofen has been researched along with paclitaxel in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (32.00)29.6817
2010's17 (68.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Agrawal, SK; Gupta, PP; Rani, R; Saxena, AK; Singh, J; Sondhi, SM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Agrawal, SK; Rani, R; Roy, P; Saxena, AK; Singh, J; Sondhi, SM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Choi, DL; Choi, HW; Choo, DJ; Chung, KS; Huh, G; Kang, HB; Kim, J; Lee, JY; Lee, KT; Park, JY; Rim, HK; Seo, JH1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Alla, M; Balasubramanian, S; Bommena, VR; Bommineni, MR; Mandha, SR; Siliveri, S1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Abdel-Maksoud, MS; Ali, EMH; Oh, CH1
Carrigan, N; Gardner, PH; Knapp, P; Raynor, DK; Woolf, E1
Ma, L; Shi, D; Yu, L; Zeng, S; Zhou, Q1
Ahmadi, F; Mohammadi-Samani, S; Montaseri, H; Sobhani, Z; Zarea, B1
Gao, Y; Jesse, W; Kieltyka, RE; Korobko, AV; Kros, A; Norder, B1
Chen, Y; Guo, X; Huang, Y; Li, S; Xu, J; Zhao, M1
Kim, JO; Nguyen, CN; Nguyen, HT; Tran, BN; Yong, CS1
Cho, Y; Kim, YD; Lee, JH; Park, HR; Song, JM; Woo, BH; Yoon, S1

Reviews

2 review(s) available for ibuprofen and paclitaxel

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Thieno[2,3-d]pyrimidine as a promising scaffold in medicinal chemistry: Recent advances.
    Bioorganic & medicinal chemistry, 2019, 04-01, Volume: 27, Issue:7

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Chemistry, Pharmaceutical; Humans; Inflammation; Neoplasms; Pyrimidines; Structure-Activity Relationship

2019

Trials

1 trial(s) available for ibuprofen and paclitaxel

ArticleYear
Perceived risk of medicine side effects in users of a patient information website: a study of the use of verbal descriptors, percentages and natural frequencies.
    British journal of health psychology, 2009, Volume: 14, Issue:Pt 3

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Attitude to Health; Culture; Drug Information Services; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Ibuprofen; Internet; Male; Medication Adherence; Middle Aged; Paclitaxel; Risk Assessment; Semantics; Young Adult

2009

Other Studies

22 other study(ies) available for ibuprofen and paclitaxel

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Synthesis, anti-inflammatory and anticancer activity evaluation of some novel acridine derivatives.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:2

    Topics: Acridines; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Carrageenan; Cell Line, Tumor; Cell Proliferation; Edema; Female; Humans; Male; Rats; Structure-Activity Relationship

2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Solvent free synthesis, anti-inflammatory and anticancer activity evaluation of tricyclic and tetracyclic benzimidazole derivatives.
    Bioorganic & medicinal chemistry letters, 2010, Apr-01, Volume: 20, Issue:7

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Benzimidazoles; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Microwaves; Neoplasms; Ovarian Neoplasms

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
In vivo evaluation of oral anti-tumoral effect of 3,4-dihydroquinazoline derivative on solid tumor.
    Bioorganic & medicinal chemistry letters, 2012, Jan-15, Volume: 22, Issue:2

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Molecular Structure; Neoplasms; Quinazolines; Structure-Activity Relationship; Xenograft Model Antitumor Assays

2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Eco-friendly synthesis and biological evaluation of substituted pyrano[2,3-c]pyrazoles.
    Bioorganic & medicinal chemistry letters, 2012, Aug-15, Volume: 22, Issue:16

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Cell Proliferation; Crystallography, X-Ray; Edema; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; MCF-7 Cells; Microbial Sensitivity Tests; Molecular Conformation; Pyrazoles; Rats

2012
Cutaneous drug reaction case reports: from the world literature.
    American journal of clinical dermatology, 2001, Volume: 2, Issue:4

    Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Aged; Amlodipine; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Anticonvulsants; Antihypertensive Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Antirheumatic Agents; BCG Vaccine; Cefotetan; Cephamycins; Contrast Media; Cysteine; Dapsone; Diltiazem; Dipyrone; Docetaxel; Drug Eruptions; Echinacea; Enoxaparin; Female; Fructose; Glucans; Glucose; Gold Sodium Thiomalate; Humans; Ibuprofen; Icodextrin; Ioxaglic Acid; Male; Middle Aged; Minocycline; Paclitaxel; Pregnancy; Solvents; Taxoids; Topiramate; Triamcinolone; Trichloroethylene

2001
Influence of CYP2C8 polymorphisms on the hydroxylation metabolism of paclitaxel, repaglinide and ibuprofen enantiomers in vitro.
    Biopharmaceutics & drug disposition, 2013, Volume: 34, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Aryl Hydrocarbon Hydroxylases; Baculoviridae; Carbamates; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C8; Cytochromes b5; Genetic Vectors; Genome-Wide Association Study; Humans; Hydroxylation; Hypoglycemic Agents; Ibuprofen; Liver; Paclitaxel; Piperidines; Polymorphism, Genetic

2013
Enhanced oral bioavailability of paclitaxel by concomitant use of absorption enhancers and P-glycoprotein inhibitors in rats.
    Journal of chemotherapy (Florence, Italy), 2013, Volume: 25, Issue:6

    Topics: Absorption; Administration, Oral; Animals; Antineoplastic Agents; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Biological Availability; Cyclosporine; Ibuprofen; Male; Paclitaxel; Permeability; Rats; Rats, Sprague-Dawley; Solubility; Verapamil

2013
Thiolated human serum albumin cross-linked dextran hydrogels as a macroscale delivery system.
    Soft matter, 2014, Jul-21, Volume: 10, Issue:27

    Topics: Dexamethasone; Dextrans; Dithionitrobenzoic Acid; Drug Carriers; Drug Liberation; Humans; Hydrogels; Ibuprofen; Paclitaxel; Serum Albumin

2014
PEG-Fmoc-Ibuprofen Conjugate as a Dual Functional Nanomicellar Carrier for Paclitaxel.
    Bioconjugate chemistry, 2016, 09-21, Volume: 27, Issue:9

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Carriers; Drug Liberation; Female; Fluorenes; Ibuprofen; Kinetics; Mice; Mice, Inbred BALB C; Micelles; Paclitaxel; Polyethylene Glycols; Tissue Distribution

2016
Combination of a chemopreventive agent and paclitaxel in CD44-targeted hybrid nanoparticles for breast cancer treatment.
    Archives of pharmacal research, 2017, Volume: 40, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Carriers; Drug Delivery Systems; Drug Screening Assays, Antitumor; Female; Humans; Hyaluronan Receptors; Hyaluronic Acid; Ibuprofen; Nanoparticles; Paclitaxel; Tumor Cells, Cultured

2017
Oral Administration of
    International journal of molecular sciences, 2019, May-21, Volume: 20, Issue:10

    Topics: Administration, Oral; Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Ibuprofen; Inflammation; Male; Mice; Paclitaxel; Porphyromonas gingivalis; Xenograft Model Antitumor Assays

2019