ibuprofen and niacin

ibuprofen has been researched along with niacin in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.56)18.2507
2000's2 (11.11)29.6817
2010's13 (72.22)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Bao, R; He, L; Ju, Y; Li, C; Luo, Y; Sang, Z; Song, R; Sun, K; Yang, T; Yang, Y; Zhou, Y1
Higashida, H; Maeda, H; Ogihara, T; Sai, Y; Takanaga, H; Tamai, I; Tsuji, A1
Fei, YJ; Ganapathy, V; Gopal, E; Itagaki, S; Miyauchi, S; Prasad, PD; Zhuang, L1
Abu Zanat, FZ; Qandil, AM; Tashtoush, BM1
Junyaprasert, VB; Kreuter, J; Sripha, K; Suksiriworapong, J1
Bolas-Fernandez, F; Dea-Ayuela, MA; Galiana, C; Healy, AM; Mugheirbi, NA; O'Connell, P; Serrano, DR; Walsh, D; Worku, ZA1
Cristina, RH; María Jesús, MV; Miguel Ángel, BL; Rut, FT1
Bello-López, MÁ; López-Pérez, G; Martín-Valero, MJ; Román-Hidalgo, C1
Fujita, T; Kono, Y; Yuri, T1

Reviews

1 review(s) available for ibuprofen and niacin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

17 other study(ies) available for ibuprofen and niacin

ArticleYear
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Discovery of Novel Peptidomimetic Boronate ClpP Inhibitors with Noncanonical Enzyme Mechanism as Potent Virulence Blockers
    Journal of medicinal chemistry, 2020, 03-26, Volume: 63, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Boron Compounds; Boronic Acids; Endopeptidase Clp; Female; Glycine; Humans; Methicillin-Resistant Staphylococcus aureus; Mice, Inbred BALB C; Molecular Docking Simulation; Molecular Structure; Peptidomimetics; Protein Binding; Serine Proteinase Inhibitors; Skin; Small Molecule Libraries; Staphylococcal Skin Infections; Structure-Activity Relationship; Virulence

2020
Participation of a proton-cotransporter, MCT1, in the intestinal transport of monocarboxylic acids.
    Biochemical and biophysical research communications, 1995, Sep-14, Volume: 214, Issue:2

    Topics: Animals; Biological Transport; Carboxylic Acids; Carrier Proteins; CHO Cells; Cricetinae; Female; Hydrogen-Ion Concentration; Ibuprofen; Intestinal Mucosa; Lactates; Mandelic Acids; Membrane Proteins; Monocarboxylic Acid Transporters; Niacin; Oocytes; Pravastatin; Propionates; Protons; Rabbits; Recombinant Proteins; RNA, Complementary; RNA, Messenger; Stereoisomerism; Transcription, Genetic; Transfection; Valproic Acid; Xenopus laevis

1995
Interaction of ibuprofen and other structurally related NSAIDs with the sodium-coupled monocarboxylate transporter SMCT1 (SLC5A8).
    Pharmaceutical research, 2006, Volume: 23, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cation Transport Proteins; Cell Line; Dose-Response Relationship, Drug; Fenoprofen; Humans; Ibuprofen; Membrane Potentials; Molecular Structure; Monocarboxylic Acid Transporters; Niacin; Oocytes; Propionates; Sodium; Structure-Activity Relationship; Transfection; Xenopus laevis

2006
A promising codrug of nicotinic acid and ibuprofen for managing dyslipidemia. I: synthesis and in vitro evaluation.
    Drug development and industrial pharmacy, 2011, Volume: 37, Issue:9

    Topics: Animals; Cyclooxygenase Inhibitors; Drug Combinations; Drug Design; Dyslipidemias; Half-Life; Humans; Hydrolysis; Hypolipidemic Agents; Ibuprofen; Male; Niacin; Rats; Rats, Wistar

2011
Functionalized (poly(ɛ-caprolactone))₂-poly(ethylene glycol) nanoparticles with grafting nicotinic acid as drug carriers.
    International journal of pharmaceutics, 2012, Feb-28, Volume: 423, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Cells, Cultured; Chemistry, Pharmaceutical; Diffusion; Drug Carriers; Drug Compounding; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Indomethacin; Kinetics; Models, Chemical; Nanoparticles; Nanotechnology; Niacin; Particle Size; Polyesters; Polyethylene Glycols; Solubility; Technology, Pharmaceutical

2012
Optimising the in vitro and in vivo performance of oral cocrystal formulations via spray coating.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2018, Volume: 124

    Topics: Administration, Oral; Aerosols; Aminosalicylic Acid; Animals; Anti-Bacterial Agents; Biological Availability; Crystallization; Delayed-Action Preparations; Drug Combinations; Drug Compounding; Drug Liberation; Drug Stability; Feasibility Studies; Ibuprofen; Mice; Niacin; Niacinamide; Solubility; Staphylococcus aureus; Sulfamethazine; Technology, Pharmaceutical

2018
Use of Polymer Inclusion Membranes (PIMs) as support for electromembrane extraction of non-steroidal anti-inflammatory drugs and highly polar acidic drugs.
    Talanta, 2018, Mar-01, Volume: 179

    Topics: Amoxicillin; Anti-Inflammatory Agents, Non-Steroidal; Cellulose; Electrochemical Techniques; Hippurates; Ibuprofen; Ketoprofen; Membranes, Artificial; Naproxen; Niacin; ortho-Aminobenzoates; Quaternary Ammonium Compounds; Salicylic Acid

2018
Chitosan tailor-made membranes as biopolymeric support for electromembrane extraction.
    Talanta, 2019, Jul-01, Volume: 199

    Topics: Amoxicillin; Biopolymers; Chitosan; Electrochemical Techniques; Hippurates; Humans; Ibuprofen; Ketoprofen; Naproxen; Niacin; ortho-Aminobenzoates; Salicylic Acid

2019
Transport characteristics of 5-aminosalicylic acid into colonic epithelium: Involvement of sodium-coupled monocarboxylate transporter SMCT1-mediated transport system.
    Biochemical and biophysical research communications, 2020, 04-09, Volume: 524, Issue:3

    Topics: Animals; Biological Transport; Ibuprofen; Intestinal Mucosa; Lactic Acid; Male; Mesalamine; Mice, Inbred ICR; Monocarboxylic Acid Transporters; Niacin; Sodium; Substrate Specificity; Tritium

2020