ibuprofen has been researched along with naproxen in 681 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 132 (19.38) | 18.7374 |
| 1990's | 82 (12.04) | 18.2507 |
| 2000's | 163 (23.94) | 29.6817 |
| 2010's | 237 (34.80) | 24.3611 |
| 2020's | 67 (9.84) | 2.80 |
| Authors | Studies |
|---|---|
| Heikes, JE; Sprague, PW | 1 |
| Bell, MR; D'Ambra, TE; Daum, SJ; Eissenstat, MA; Herrmann, JL; Hlasta, DJ; Kumar, V; Philion, RE; Rosi, D; Wetzel, JR | 1 |
| Carty, TJ; Moore, PF; Mylari, BL; Zembrowski, WJ | 1 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Millonig, RC; Rovnyak, GC; Schwartz, J; Shu, V | 1 |
| Boettcher, I; Elger, W; Kirsch, G; Siegmund, F; Wachtel, H | 1 |
| Ariyan, ZS; Fogt, SW; Heilman, RD; Matthews, RJ; Powers, LJ; Rippin, DJ | 1 |
| Copeland, RA; Covington, M; Trzaskos, JM; Wilkerson, WW | 1 |
| Calhoun, W; Carlson, RP; Crossley, R; Datko, LJ; Dietrich, S; Heatherington, K; Marshall, LA; Meade, PJ; Opalko, A; Shepherd, RG | 1 |
| Bell, RL; Bouska, J; Brooks, CD; Carter, GW; Dellaria, JF; Hulkower, KI; Kolasa, T; Rodriques, KE; Summers, JB | 1 |
| Bohlin, L; Danielson, H; Noreen, Y; Perera, P; Ringbom, T | 1 |
| Darolia, R; Dobson, RL; Eichhold, TH; Enzweiler, K; Farmer, RW; Gan, L; Green, SA; Hennes, D; Janusz, JM; Kellstein, DE; Kuhlenbeck, DL; Magrisso, IJ; Matthews, RS; Ridgeway, JM; Rosario-Jansen, T; Scherz, MW; Sirko, SP; Tulich, JL; Wehmeyer, KR; Wu, LI; Young, PA | 1 |
| Dobson, RL; Eichhold, TH; Enzweiler, K; Gan, L; Green, SA; Janusz, JM; Johnson, CR; Kellstein, DE; Kuhlenbeck, DL; Magrisso, IJ; McDow-Dunham, KL; Pikul, S; Rosario-Jansen, T; Scherz, MW; Senanayake, CB; Tulich, JL; Wehmeyer, KR; Wu, LI; Young, PA | 1 |
| Chen, J; Dobson, RL; Eichhold, TH; Enzweiler, K; Gan, L; Green, SA; Janusz, JM; Kellstein, DE; Kuhlenbeck, DL; Magrisso, IJ; Ridgeway, JM; Rosario-Jansen, T; Scherz, MW; Tulich, JL; Wehmeyer, KR; Wu, LI; Young, PA | 1 |
| Bohlin, L; Noreen, Y; Perera, P; Ringbom, T; Segura, L | 1 |
| Booren, AM; Chang, YC; DeWitt, DL; Gray, JI; Nair, MG; Strasburg, GM; Wang, H | 1 |
| Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S | 1 |
| DeWitt, DL; Mattson, WG; Nair, MG; Ramsewak, RS; Zasada, J | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Cihlar, T; Ho, ES; Mulato, AS | 1 |
| Faller, B; Wohnsland, F | 1 |
| Abe, T; Itoh, T; Kato, Y; Kusuhara, H; Meier, PJ; Shitara, Y; Sugiyama, D; Sugiyama, Y | 1 |
| Cochran, FR; Cooper, BR; Jones, ML; Kelley, JL; Musso, DL; Orr, GF; Rigdon, GC; Selph, JL | 1 |
| Arun, KH; Bharatam, PV; Chawla, HP; Jachak, SM; Johar, PS; Malde, A; Mittal, S; Ramarao, P; Selvam, C | 1 |
| Charitos, C; Doulgkeris, C; Galanakis, D; Gavalas, A; Kourounakis, AP; Kourounakis, PN; Kravaritou, C; Rekka, EA; Tsiakitzis, KC | 1 |
| Beroza, P; Cai, D; Damodaran, K; Gomez, RF; Hsu, N; Keck, JG; Laborde, E; Lum, RT; Macke, TJ; Martin, G; Schow, SR; Simon, RJ; Villar, HO; Wick, MM | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Caron, G; Ermondi, G | 1 |
| Brozic, P; Gobec, S; Rizner, TL | 1 |
| Bain, G; Beher, D; Chen, W; Jiang, X; Munoz, B; Peachey, J; Prasit, P; Shearman, MS; St-Jacques, R; Stock, N; Williamson, TL; Wrigley, JD | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Anderluh, M; Brunskole, M; Gobec, S; Lanisnik Rizner, T; Stefane, B; Stojan, J; Zorko, K | 1 |
| Abdel-Azeem, AZ; Abdel-Hafez, AA; El-Karamany, GS; Farag, HH | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Avdeef, A; Tam, KY | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P | 1 |
| Akamatsu, M | 1 |
| Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Abdellatif, KR; Chowdhury, MA; DuMond, JF; Huang, Z; King, SB; Knaus, EE; Reisz, JA; Velázquez, CA | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
| Horie, T; Horiguchi, A; Kitamura, S; Kotake, Y; Ohshita, H; Ohta, S; Sanoh, S; Sugihara, K; Tateno, C; Tayama, Y | 1 |
| Kumar, M; Sinha, VR; Thareja, S | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Ambrosi, G; Bauer, J; Elkady, M; Laufer, SA; Luderer, S; Nieß, R; Schaible, AM; Werz, O | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Bhardwaj, A; Huang, Z; Kaur, J; Knaus, EE; Sharma, SK; Wuest, F | 1 |
| Capim, SL; Dos Santos, GC; Gonçalves, GM; Marinho, BG; Vasconcellos, ML | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Brewster, C; Deering-Rice, CE; Reilly, CA; Rose, TM | 1 |
| Alcaraz, B; Bratoeff, E; Cabeza, M; Camacho-Arroyo, I; Garrido, M; González-Arenas, A | 1 |
| Kourounakis, PN; Kourti, M; Rekka, EA; Theodosis-Nobelos, P; Tziona, P | 1 |
| Gavalas, A; Kourti, M; Rekka, EA; Theodosis-Nobelos, P | 1 |
| Amin, S; Karelia, DN; Pandey, MK; Plano, D; Sharma, AK; Spallholz, JE | 1 |
| Aytaç, PS; Çetin-Atalay, R; Durmaz, I; Houston, DR; Tozkoparan, B | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, TA; Nakagawa, A; Smith, CE; Soti, S; Xue, D; Yin, H | 1 |
| Anastácio Furtado Pacheco, P; Arruda, JC; Bello, ML; Castro, HC; da Silva, FC; Dantas, LP; de Freitas, HR; de Melo Reis, RA; Faria, RX; Ferreira, LBG; Ferreira, VF; Gonzaga, DTG; Moreira Maramaldo Costa, TE; Penido, C; Rodrigues, CR; Sposito Simões, AP; von Ranke, NL | 1 |
| Ameen, BAH; Dissanayake, AA; Nair, MG | 1 |
| Boixareu, N; Campanera, JM; Navarro, L; Pors, K; Pouplana, R; Pujol, MD; Rosell, G; Sánchez, S | 1 |
| Ahmed, R; Boulton, S; Cheng, X; Melacini, G; Selvaratnam, R; Van, K | 1 |
| Huang, S; Li, Y; Liu, W; Zhang, K; Zheng, X | 1 |
| Daniel Pedro-Hernández, L; Hernández-Montalbán, C; Martínez-García, M; Martínez-Klimova, E; Ramírez-Ápan, T | 1 |
| DeRose, EF; Duff, MR; Gabel, SA; Howell, EE; Krahn, JM; London, RE; Pedersen, LC | 1 |
| Altman, RA; Borel, T; Davis, I; de Azambuja, F; Johnson, D; Liu, A; Sorrentino, JP; Udokwu, C; Yang, Y | 1 |
| Ding, F; Gao, Y; Guo, Y; He, X; Li, S; Li, X; Liu, Z; Nie, Y; Wen, D; Zhang, Y; Zhong, M | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Mann, NS; Sachdev, AJ | 1 |
| Huskisson, EC | 1 |
| Cavalli-Björkman, K; Jacobson, J; Lundström, V; Nilsson, B; Norbeck, M | 1 |
| Lipsmeyer, EA | 1 |
| Hart, FD | 1 |
| Hadler, NM; Kilpatrick, FW | 1 |
| Jabbs, JM; Maddi, VI; Pinals, RS; Runge, LA | 1 |
| Miehlke, K | 1 |
| Roe, RL | 1 |
| Arendt-Racine, EC; Atkinson, MH; Decoteau, WE; Flatt, VL; Varady, J | 1 |
| Cohen, GN; Fisherman, EW | 1 |
| Burdeĭnyĭ, AP | 1 |
| Pemberton, RE; Strand, LJ | 1 |
| Spisani, S; Traniello, S; Vanzini, G | 1 |
| Chen, TT; Lanza, FL; Nelson, RS; Rack, MF; Royer, GL; Seckman, CE | 2 |
| Ciccolunghi, SN; Reddrop, R; Schubiger, BI | 1 |
| Scherbel, AL | 1 |
| McIntyre, BA; Philp, RB | 2 |
| Bowden, RE; Keiser, HR; Kimberly, RP; Plotz, PH | 1 |
| Brooks, PM | 1 |
| Irwin, WJ; Slack, JA | 1 |
| Balme, HW; Franklin, S; Huskisson, EC; Scott, J; Woolf, DL | 1 |
| Kaye, RL; Pemberton, RE | 1 |
| Bacon, PA; Chan, R; Collins, AJ; Crook, D | 1 |
| Turner, R | 1 |
| Kitchen, EA; Meacock, SC | 1 |
| Zarro, VJ | 1 |
| Docken, W; Kantrowitz, FG | 1 |
| Healey, LA | 1 |
| Guyonnet, JC; Julou, L | 1 |
| Alván, G | 1 |
| Kameyama, T; Mukaide, A | 2 |
| Garg, A | 1 |
| Blagbrough, IS; Daykin, MM; Doherty, M; Pattrick, M; Shaw, PN | 1 |
| Aranda, JV; Chemtob, S; Malcolm, D; Parys-Van Ginderdeuren, R; Varma, DR | 1 |
| Castonguay, A; Jalbert, G | 1 |
| Crider, AM; Dick, RM; Gokhale, R; Harpalani, A; Shanbhag, VR | 1 |
| Jones, ME; Knights, KM | 1 |
| Goldhaber, P; Hall, CM; Howell, TH; Jeffcoat, MK; Johnson, HG; Odle, BM; Offenbacher, S; Smith, MA; Williams, RC | 1 |
| Bradley, JD; Brater, DC; Hall, SD; Jones, DR; Krohn, K; Tracy, TS | 1 |
| Petersen, CS; Thomsen, K | 1 |
| Blackburn, WD; Chatham, WW; Heck, LW; Loose, LD | 1 |
| Aranda, JV; Barna, T; Beharry, K; Chemtob, S; Varma, DR | 1 |
| Barthwal, M; Srivastava, K | 1 |
| Ambrus, JL; Chesky, L; Engler, RJ; Haneiwich, S; McFarland, P | 1 |
| Calin, A; Elswood, J | 1 |
| Bissett, DL; Chatterjee, R; Hannon, DP | 1 |
| Casady, RL; Itoh, T; Magavi, R; Nishihata, T; Rytting, JH | 1 |
| Fritz, ME; Green, MD; Mayambala, CS; Odle, BM; Offenbacher, S; Sena, FJ; Smith, MA; van Dyke, TE; Yeh, KC | 1 |
| Aabakken, L; Larsen, S; Osnes, M | 1 |
| Mayer, JM | 1 |
| Kakodkar, SV; Zief, M | 1 |
| Christensen, S; Dousa, TP; Homma, S; Kusano, E; Murayama, N; Werness, JL; Yusufi, AN | 1 |
| Dasgupta, PK; Murthy, PS; Srivastava, AK; Srivastava, K | 1 |
| Bartolucci, C; Maître, JM; Mayer, JM; Testa, B | 1 |
| Bennett, A; Capasso, F; Tavares, IA; Vine, ND | 1 |
| Andersch, B; Milsom, I | 2 |
| Faulkner, G; Langman, M; Somerville, K | 1 |
| Paulus, HE; Schlegel, SI | 1 |
| Fujimura, H; Hidaka, T; Hiramatsu, Y; Hosoe, K; Watanabe, K; Yamashita, T | 1 |
| Breckwoldt, M; Zahradnik, HP | 1 |
| Lanza, F; Lynn, M; Rack, MF; Sanda, M; Wolf, J | 1 |
| Atkinson, LK; Goodship, TH; Ward, MK | 1 |
| Kothari, HV; Ku, EC; Lee, W; Scholer, DW | 1 |
| Sallmann, AR | 2 |
| Griswold, DE; Hanna, N; Schwartz, L; Webb, E | 1 |
| Denlinger, RH; Elliott, GA; Purmalis, A; VanderMeer, DA | 1 |
| Crittenden, N; Fitzpatrick, F; McGee, J; McGuire, J | 1 |
| Greenwood, A; Huskisson, EC | 1 |
| Hollenberg, MD; Itoh, H; Lederis, K; Muramatsu, I; Patel, P | 1 |
| Jenner, PN | 1 |
| Giercksky, KE | 1 |
| Zuckner, J | 1 |
| Altman, R | 1 |
| Catalano, MA | 1 |
| Meisel, AD | 1 |
| Anderson, SA; Brater, DC; Brown-Cartwright, D | 1 |
| Kapadia, L | 1 |
| Frizziero, L; Zizzi, F | 1 |
| Keat, AC; Keat, EC; Ravi, S | 1 |
| McGill, PE | 1 |
| Anderson, S; Baird, B; Brater, DC; Campbell, WB | 1 |
| Anderson, S; Goldberg, M; Gross, J; Kantrowitz, F; Menander-Huber, K; Taborn, J | 1 |
| Wilson, JT | 1 |
| Kayrouz, T; Pivarnik, J; Senay, LC | 1 |
| Kimble, EF; Kothari, HV; Ku, EC; Lee, W; Liauw, L; Tjan, J | 1 |
| Kimble, EF; Kothari, H; Ku, EC; Lee, W; Liauw, LH | 1 |
| Gasparich, JP; Mayo, ME | 1 |
| Buchanan, WW; Kassam, YB | 1 |
| Gilfillan, AM; Rooney, SA | 1 |
| Foley, RJ; Reeves, WB; Weinman, EJ | 1 |
| Høyeraal, HM; Kåss, E; Kvien, TK | 1 |
| Hudyma, EO; Kollenberg, LO; Robbins, JM | 1 |
| Caldwell, JR | 1 |
| Machtey, I | 1 |
| Caldwell, J; Hutt, AJ | 1 |
| Hanson, FW | 1 |
| Klicius, J; Martel, RR; Metcalf, G; Rona, GA | 1 |
| Caldwell, JR; Crain, D; Hoffmeister, RT; Kantrowitz, F; Lloyd, RJ; Nussdorf, RT; Repice, MR; Schmid, FR | 1 |
| Chan, WY | 1 |
| Cooper, SA | 1 |
| Clarke, TK; Mungavin, JM | 1 |
| Altman, RD | 1 |
| Ward, JR | 1 |
| Carlsson, I; Wennmalm, A | 1 |
| Owen, PR | 1 |
| Chremos, AN; Dunn, MJ; Zambraski, EJ | 1 |
| Bjelle, A; Mjörndal, T | 1 |
| Lanza, FL | 1 |
| Bhalla, AK; Simon, LS | 1 |
| Cronberg, S; Söderberg, I; Wallmark, E | 1 |
| Datta, H; Gupta, U; Mathur, VS; Thomas, KJ | 1 |
| Amadio, P | 1 |
| Court, H; Volans, GN | 1 |
| Chan, WY; Powell, AM | 1 |
| Gritsiuk, AI; Kreminskaia, NK; Vitruk, SK | 1 |
| Isomäki, H; Kaarela, K; Kajander, A; Koota, K; Lehtinen, K; Luukkainen, R; Martio, J; Martio, T; Nissilä, M; Nuotio, P | 1 |
| Babayan, RK; Krane, RJ; Kraus, SE; Siroky, MB | 1 |
| Obel, AO | 1 |
| Das, KV; Joseph, PP; Philip, J | 1 |
| Ciofalo, VB; Diamantis, W; Melton, J; Sofia, RD | 1 |
| Fraser, IS | 1 |
| Avery, GS; Brogden, RN; Heel, RC; Pakes, GE; Speight, TM | 1 |
| Laiwah, AC; Mactier, RA | 1 |
| Alvin, PE; Litt, IF | 1 |
| Bennedsen, J; Nielsen, H | 1 |
| Bailey, RR; Lynn, KL; Munn, E | 1 |
| Keinänen-Kiukaanniemi, S; Kouvalainen, K; Similä, S | 1 |
| Cooper, SL | 1 |
| Zizic, TM | 1 |
| Mills, JA; Simon, LS | 1 |
| Gallardo, F; Rossi, E | 1 |
| Dieppe, P; Doyle, D; Jacoby, R | 1 |
| Dingfelder, JR | 1 |
| Pathy, MS | 1 |
| Goodwin, JS; Regan, M | 1 |
| Nash, DP | 1 |
| Fung, WP; Matz, L; Papadimitriou, JM | 1 |
| Engler, C; Seifert, MH | 1 |
| Bijlsma, JW; Lems, WF; van Berge Henegouwen, GP | 1 |
| Lange, R; Lentz, R | 1 |
| Kajiyama, G; Lane, NE; Smith, RL | 1 |
| Chemtob, S; Hanna, N; Lachapelle, P; Orquin, J; Roy, MS; Varma, DR | 1 |
| Ginsberg, D; Gray, J; Houston, MC; Kaihlenen, PM; Lefkowitz, M; Runde, M; Sugimoto, D; Szeto, C; Weir, M | 1 |
| Avnir, D; Bialer, M; Ladkani, D; Samara, E | 1 |
| Bilodeau, JF; Castonguay, A; Chung, FL; Wang, M | 1 |
| Clearkin, LG; Scott, JA | 1 |
| Grahn, A; Hermansson, J | 1 |
| Fournel-Gigleux, S; Magdalou, J; Pritchard, M; Siest, G | 1 |
| Goodfriend, TL; Klassen, D; Peterson, CA; Schuna, AA; Young, DY | 1 |
| Duncan, KM; Hart, LL | 1 |
| Farris, KB; Kaplan, B; Kirking, DM | 1 |
| DeLapp, RE; Eversmeyer, W; Jensen, CP; Poland, M | 1 |
| DeLapp, RE; Morgan, GJ; Poland, M | 1 |
| DeLapp, RE; Lister, BJ; Poland, M | 1 |
| Alfredsson, L; Kaufman, DW; Kelly, JP; Koff, RS; Laszlo, A; Shapiro, S; Sheehan, JE; Wiholm, BE | 1 |
| Chiao, SF; Chu, KM; Ho, ST; Ho, W; Hu, OY; Liu, HS | 1 |
| Cahill, RJ; Gilvarry, J; O'Morain, CA; Sant, SM | 1 |
| Guttman, A | 1 |
| Bopp, BA; Kukulka, MJ; Machinist, JM | 1 |
| Mue, S; Ohuchi, K; Watanabe, M; Yamada, M | 1 |
| Cheruvallath, VK; Lindenbaum, S; Narayanan, SR; Perrin, JH; Riley, CM | 2 |
| Dasgupta, A; Volk, A | 1 |
| Dasgupta, A; Timmerman, TG | 1 |
| Becker, L; Eberlein-König, B; Przybilla, B | 1 |
| Akatsu, T; Consolaro, A; Guimarães, SA; Tago, EM | 1 |
| Fox, SM; Johnston, SA | 1 |
| Caruso, FS; Frenk, H; Lu, J; Mao, J; Mayer, DJ; Price, DD | 1 |
| Coletta, I; Guglielmotti, A; Landolfi, C; Mantovani, A; Milanese, C; Pinza, M; Polenzani, L; Sironi, M; Soldo, L; Vecchi, A | 1 |
| Giri, AK; Khan, KA; Philipose, B; Singh, R | 1 |
| Landt, M; Smith, CH; Way, BA; Wilhite, TR | 1 |
| Casini, ML; Mattei, E; Panzironi, C; Saso, L; Silvestrini, B; Valentini, G | 1 |
| Dajani, EZ | 1 |
| Li Wan Po, A; Zhang, WY | 1 |
| Jennis, T; Lu, HC; Marcus, S; Ruck, B; Shih, RD | 1 |
| Schnitzer, TJ | 1 |
| Barzoi, G; De Santis, D; Finco, G; Gilli, E; Gottin, L; Ischia, S; Polati, E; Salgarelli, A | 1 |
| Hawkey, CJ | 1 |
| el-Bary, AA; el-Nabarawi, MA; Mohamed, MI | 1 |
| Kaplan, BS; Schaller, S | 1 |
| Karateev, DE | 1 |
| Gierse, JK; Isakson, PC; Koboldt, CM; Seibert, K; Walker, MC | 1 |
| Duque-Oliart, A; García-Rodríguez, LA; Pérez-Gutthann, S; Varas-Lorenzo, C | 1 |
| Ikeda, M; Koshika, A; Miyajima, M; Okada, J | 1 |
| Citra, M; Freedman, TB; Long, F; Nafie, LA | 1 |
| Iley, J; Mendes, E; Moreira, R; Souza, S | 1 |
| Wallace, JL | 1 |
| Cullen , DJ; Doherty, M; Garner, S; Garrud, P; Hawkey, CJ; Holmes, S; Logan, RF; Maynard, A; Seager, JM; Wilson, JV | 1 |
| Cullen, DJ; Doherty, M; Garner, S; Garrud, P; Hawkey, CJ; Holmes, S; Logan, RF; Maynard, A; Pearson, G; Seager, JM; Wilson, JV | 1 |
| Pedersen-Bjergaard, S; Rasmussen, KE | 1 |
| Callahan, LF; Cummins, P; Pincus, T; Swearingen, C | 1 |
| Hercegová, A; Polonský, J; Sádecká, J | 1 |
| Arnout, J; Buntinx, A; Dallob, A; De Lepeleire, I; De Schepper, PJ; Depré, M; Ebel, DL; Gertz, BJ; Schwartz, JI; Tanaka, W; Van Hecken, A; Wong, PH; Wynants, K | 1 |
| Chen, X; Luo, Q; Ni, J; Wang, H; Zhang, Q; Zou, H | 1 |
| Haginaka, J; Sanbe, H | 1 |
| Applebaum, H; Ko, A; O'Connell, T; Su, W | 1 |
| Brown, J; Fricke, J; Kotey, P; Mehlisch, D; Morrison, BW; Yuan, W | 1 |
| Alano, MA; Konduri, GG; Ngougmna, E; Ostrea, EM | 1 |
| Agarwal, V; Liu, P; Shah, A; Sundaresan, P; Woodruff, M | 1 |
| Tive, L | 1 |
| Cakrt, M; Hercegová, A; Polonský, J; Sádecká, J; Skacáni, I | 1 |
| Bujak-Gizycka, B; Kłys, M; Latacz, B; Skupień, E | 1 |
| Mason, JC; Patonay, G; Sowell, J; Strekowski, L | 1 |
| Browning, RA; Burgess, FW | 1 |
| Barrio, DA; Cortizo, AM; Etcheverry, SB; Williams, PA | 1 |
| Evans, JM; MacDonald, TM; McMahon, AD | 1 |
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| González-Gay, MA; González-Juanatey, C | 1 |
| Castelli, G; King, D; Petrone, A; Shrader, C; Xiang, J | 1 |
| Laaksonen, T; Paukkonen, H; Szilvay, G; Ukkonen, A; Yliperttula, M | 1 |
| Nurmohamed, MT | 1 |
| Drewes, JE; Graßmann, J; Letzel, T; Stadlmair, LF | 1 |
| Burton, D; Jamieson, R; Khosravi, K; Price, GW; Zhang, Y | 1 |
| Jung, JA; Parvez, MM; Shin, HJ; Shin, JG | 1 |
| Groza, LG; Hebig, KH; Ptacek, CJ; Sabourin, MJ; Scheytt, TJ | 1 |
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| Bao, W; Borer, J; Graham, DY; Husni, EM; Libby, P; Lincoff, MA; Lüscher, T; Nissen, SE; Walker, C; Wang, Q; Wisniewski, LM; Wolski, K; Yeomans, ND | 1 |
| Bao, W; Borer, JS; Graham, DY; Husni, ME; Libby, P; Lincoff, AM; Lüscher, TF; Nissen, SE; Solomon, DH; Stevens, T; Vargo, J; Walker, C; Wang, Q; Wisniewski, LM; Wolski, KE; Yeomans, ND | 1 |
| Antman, EM | 1 |
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| Falås, P; Hermes, N; Jewell, KS; Joss, A; Nielsen, JL; Ternes, TA; Wick, A | 1 |
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| Graham, DY; Yeomans, ND | 1 |
| Chopade, SA; Early, JT; Guo, Y; Hillmyer, MA; Lodge, TP; Sun, CC; Tang, B; Wang, C; Wang, E | 1 |
| Debrauwer, L; Ghorbel-Abid, I; Kalfat, R; Khazri, H; Trabelsi-Ayadi, M | 1 |
| Pedersen, L; Schmidt, M; Sørensen, HT | 1 |
| Du, Y; Fu, Y; Gao, X; Geng, J; Li, S; Ren, H; Wu, G | 1 |
| Monteiro, HP; Paiva, DR; Reginato, MM; Reis, AKCA; Sensato, FR | 1 |
| Buschiazzo, HO; Cañás, M; Dorati, CM; Mordujovich-Buschiazzo, P; Prozzi, GR; Urtasun, MA | 1 |
| Fadare, OA; Olasunkanmi, LO; Tabrizi, L | 1 |
| Escher, BI; Fischer, FC; Henneberger, L; Mühlenbrink, M | 1 |
| Gomaa, H; Sabouni, R | 1 |
| Grudniewska, A; Kiełbowicz, G; Kocbach, B; Kłobucki, M; Maciejewska, G; Ugorski, M; Urbaniak, A; Wawrzeńczyk, C | 1 |
| Husni, ME; Nissen, S; Paynter, N; Shao, M; Solomon, DH; Wolski, K | 1 |
| Ma, R; Qu, H; Wang, B; Wang, F; Yu, G; Yu, Y | 1 |
| Bello-López, MÁ; López-Pérez, G; Martín-Valero, MJ; Román-Hidalgo, C | 1 |
| Sanàti, SE; Seidi, S | 1 |
| Nissen, SE; Reed, GW | 1 |
| Ciorîţă, A; Copolovici, D; Copolovici, L; Lung, I; Opriş, O; Soran, ML | 1 |
| Escobedo-Hinojosa, W; Hauer, B; Klenk, JM; Kontny, LH; Nebel, BA | 1 |
| Ao, X; Li, C; Li, S; Lu, Z; Sun, W; Yang, C | 1 |
| Amiri, A; Derakhshanrad, S; Mirzaei, M | 1 |
| Ding, T; Li, J; Wang, S; Yang, B | 1 |
| Aydin, ME; Aydin, S; Ulvi, A | 1 |
| Herrera, RC; Vazquez, ALR; Y de la Pena, MH | 1 |
| Khaibrakhmanova, D; Nikiforova, A; Sedov, I | 1 |
| Białk-Bielińska, A; Grabarczyk, Ł; Mulkiewicz, E; Pazda, M; Puckowski, A; Stepnowski, P; Stolte, S | 1 |
| Brinkmann, J; Luebbert, C; Rest, F; Sadowski, G | 1 |
| Chen, Y; Hao, C; Nie, W; Wang, L; Xu, P; Yin, Y | 1 |
| Barceló, D; López-Doval, JC; Rodríguez-Mozaz, S; Sabater, S; Serra-Compte, A | 1 |
| Bresnick, KA; Hatch, EE; Huybrechts, KF; Mikkelsen, EM; Rothman, KJ; Wang, TR; Wesselink, AK; Wise, LA | 1 |
| Andrews, GP; Jacobs, E; Jones, DS; McCoy, CP; Tian, Y; Wu, H | 1 |
| Parolini, M | 1 |
| Akerman, S; Andreou, AP; Goadsby, PJ; Hoffmann, J; Holland, PR; Summ, O | 1 |
| Hirokawa, T; Kobayashi, T; Misaka, T; Nakagita, T; Narukawa, M; Taketani, C | 1 |
| Arreguin-Campos, R; Caldara, M; Cleij, TJ; Diliën, H; Eersels, K; Heidt, B; Jimenez-Monroy, KL; Lowdon, JW; Rogosic, R; van Grinsven, B | 1 |
| Daković, A; de Gennaro, B; Galzerano, B; Germinario, C; Izzo, F; Langella, A; Rottinghaus, GE; Smiljanić, D | 1 |
| De Aramburu Mera, T; Ochando Díez-Canseco, M; Prados Castaño, M; Reguero Capilla, M | 1 |
| Abranches, DO; Benfica, J; Coutinho, JAP; Sintra, TE; Soares, BP; Ventura, SPM | 1 |
| Madikizela, LM; Ncube, S | 1 |
| Dathe, K; Fietz, AK; Hultzsch, S; Padberg, S; Paulus, W; Schaefer, C | 1 |
| Caban, M; Kumirska, J; Mulkiewicz, E; Stepnowski, P; Świacka, K; Wolecki, D | 1 |
| Davies, GL; Duan, H; Harman, CLG; Strimaite, M; Wang, Y; Williams, GR | 1 |
| Jiang, G; Li, G; Liao, C; Xiong, P; Zhang, H | 1 |
| Ha, MW; Paek, SM | 1 |
| Bączek, T; Chung, DS; Jeong, S; Kwon, JY; Kwon, W; Miękus, N; Valdez, JE | 1 |
| Ghangrekar, MM; Rastogi, A; Tiwari, MK | 1 |
| Carmona, Z; Gutierrez-Suarez, K; Moreno Ríos, AL; Ramos, CG; Silva Oliveira, LF | 1 |
| Eichhorn, T; Hey-Hawkins, E; Kaluđerović, GN; Morgan, I; Predarska, I; Saoud, M | 1 |
| Díaz de León-Martínez, L; Flores-Ramírez, R; Galván-Romero, V; Medellín-Castillo, NA; Meléndez-Marmolejo, J; Ocampo-Pérez, R; Padilla-Ortega, E; Rodríguez-Torres, I; Villarreal-Lucio, S | 1 |
| Bao, W; Davey, DA; Husni, E; Libby, P; Lüscher, TF; Nissen, SE; Obeid, S; Ruschitzka, F; Walker, C; Wang, Q; Wisniewski, LM; Wolski, KE; Xia, F | 1 |
| Boncz, MÁ; López-Serna, R; Muñoz, R; Ruas, G; Scarcelli, PG; Serejo, ML | 1 |
| Barakat, A; Diaz-delCastillo, M; Heegaard, AM; Rice, ASC; Sena, ES; Soliman, N; Vollert, J; Zhang, XY | 1 |
| Kumpangnil, K; Leksomboon, R; Pangjit, K; Udomsuk, L | 1 |
| Hou, Y; Li, S; Li, X; Liang, B; Peng, L; Wang, A; Wang, Z; Xie, L; Yun, H; Zhang, P | 1 |
| Hjemdahl, P; Stiller, CO | 1 |
| Baciu, A; Manea, F; Motoc, S; Pop, A; Vasilie, S | 1 |
| Butty, EM; Chalifoux, NV; Culler, CA; Ehrhardt, CM; Labato, MA; Londoño, LA; Lynch, AM; Mauro, KD; Moyle, RB; Robertson, JB; Suter, SE; Ueda, Y; Vigani, A | 1 |
| Ambriz-Mexicano, I; Galar-Martínez, M; Galíndez-Mayer, J; González-Juárez, S; Juárez-Ramírez, C; Ruiz-Ordaz, N; Santoyo-Tepole, F | 1 |
| Christelle, K; Jaafar, SH; Norhayati, MN | 1 |
| Abdool-Ghany, AA; Gidley, ML; Klaus, J; Sahwell, PJ; Sinigalliano, CD; Solo-Gabriele, HM | 1 |
| Gorenflo, M; Saur, P; van den Anker, JN; van Dyk, M; Welzel, T; Ziesenitz, VC | 1 |
| Kassie, GM; Kerr, M; Moffat, A; Pratt, N; Roughead, EE | 1 |
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| Bila, DM; da Fonseca, EM; da Silva de Freitas, A; de Oliveira Santos, AD; do Nascimento, MTL; Dos Santos, RF; Felix, LC; Hauser-Davis, RA; Neto, JAB; Sanson, AL | 1 |
| Al-Mousa, AA; Alsalem, MI; Altarifi, AA; Neubert, JK; Nuseir, KQ; Qaoud, AK; Younis, BA | 1 |
| Husni, ME; Minhas, D; Nidhaan, A | 1 |
| Dorazilová, J; Dvořák, M; Kubáň, P; Ryšavá, L; Sedláček, P; Vojtová, L | 1 |
| Sun, CK; Tsai, TH | 1 |
| Habara, M; Haraguchi, T; Ikezaki, H; Kawasaki, I; Kojima, H; Ohkawa, K; Ozeki, M; Uchida, T; Uno, R; Yoshida, M | 1 |
| Cappelli, C; Giovannini, T; Gómez, S; Núñez Zarur, F; Restrepo, A; Rojas-Valencia, N | 1 |
| Asonye, C; Dwumfour, N; Karami, S; McCulley, L; Pinnow, E; Pratt, V; Zhou, EH | 1 |
| Guzik, U; Hupert-Kocurek, K; Marchlewicz, A; Wojcieszyńska, D | 1 |
| Lane, NE; Lei, G; Li, X; Wei, J; Zeng, C; Zhang, Y | 1 |
| Bonnesen, K; Ehrenstein, V; Grønkjær, MS; Hallas, J; Lash, TL; Pedersen, L; Schmidt, M; Sørensen, HT | 1 |
| Dresler, T; Förderreuther, S; Gaul, C; Gossrau, G; Jürgens, TP; Ruscheweyh, R; Ruschil, V; Scheidt, J; Straube, A | 1 |
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| Apata, J; Mosholder, AD; Pennap, DD | 1 |
| Bonnesen, K; Ehrenstein, V; Lash, TL; Pedersen, L; Schmidt, M; Sørensen, HT | 1 |
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| Abbasi, S; Haeri, SA; Heydarzadeh, S; Roushani, M | 1 |
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66 review(s) available for ibuprofen and naproxen
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Antiinflammatory drugs.
Topics: Adult; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Benzylidene Compounds; Child; Drug Evaluation; Female; Humans; Ibuprofen; Indenes; Indomethacin; Ketoprofen; Mefenamic Acid; Naproxen; Phenylacetates; Phenylbutazone; Pregnancy; Pregnancy Complications; Propionates; Tolmetin | 1977 |
Drug therapy in rheumatic diseases.
Topics: Acetaminophen; Adrenal Cortex Hormones; Antimalarials; Aspirin; Colchicine; Fenoprofen; Gold; Humans; Ibuprofen; Indomethacin; Levamisole; Naproxen; Penicillamine; Phenylbutazone; Rheumatic Diseases; Tolmetin | 1977 |
[Drug therapy of ankylosing spondyloarthritis (Bechterew's disease)].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Apazone; Butadienes; Cyclophosphamide; Diclofenac; Drug Combinations; Drug Evaluation; Glycolates; Gold; Humans; Ibuprofen; Indomethacin; Ketoprofen; Levamisole; Naproxen; Oxyphenbutazone; Phenylbutazone; Salicylates; Spondylitis, Ankylosing; Sulindac | 1978 |
Treatment of rheumatoid arthritis: a review including newer and experimental anti-inflammatory agents.
Topics: Activities of Daily Living; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin; Aurothioglucose; Fenoprofen; Humans; Ibuprofen; Immunosuppressive Agents; Indomethacin; Naproxen; Oxyphenbutazone; Penicillamine; Phenylbutazone; Physical Therapy Modalities; Tolmetin | 1976 |
Stereoselective metabolism of anti-inflammatory 2-arylpropionates.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Flurbiprofen; Ibuprofen; Naproxen; Stereoisomerism; Suprofen | 1990 |
Non-steroidal and analgesic therapy in the elderly.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Apazone; Aspirin; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Diclofenac; Drug Hypersensitivity; Gastrointestinal Diseases; Hematologic Diseases; Humans; Ibuprofen; Indomethacin; Ketoprofen; Kidney Diseases; Kinetics; Naproxen; Phenylbutazone; Piroxicam; Salicylates; Thiazines | 1986 |
The propionic acids. Gastrointestinal toxicity in various species.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Digestive System; Dogs; Fenoprofen; Flurbiprofen; Haplorhini; Ibuprofen; Naproxen; Propionates; Rats; Species Specificity | 1988 |
Clinical pharmacology of pediatric antipyretic drugs.
Topics: Acetaminophen; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Child, Preschool; Choline; Diclofenac; Drug Combinations; Humans; Ibuprofen; Kinetics; Naproxen; Salicylates | 1985 |
The metabolic chiral inversion of 2-arylpropionic acids--a novel route with pharmacological consequences.
Topics: Animals; Carbazoles; Fenoprofen; Humans; Ibuprofen; Indans; Naproxen; Phenylpropionates; Propionates; Stereoisomerism | 1983 |
Prostaglandins and nonsteroidal antiinflammatory drugs in dysmenorrhea.
Topics: Anti-Inflammatory Agents; Aspirin; Contraceptives, Oral; Dysmenorrhea; Female; Humans; Ibuprofen; Indomethacin; Naproxen; ortho-Aminobenzoates; Phenylpropionates; Prostaglandins | 1983 |
New peripherally-acting oral analgesic agents.
Topics: Administration, Oral; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Diflunisal; Humans; Ibuprofen; Indoprofen; Naproxen; Pain; Pain, Postoperative; Tolmetin | 1983 |
Review of ibuprofen for osteoarthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Meclofenamic Acid; Naproxen; Osteoarthritis; Phenylbutazone; Sulindac; Tolmetin | 1984 |
Update on ibuprofen for rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Piroxicam; Sulindac; Thiazines; Tolmetin | 1984 |
Practical therapeutics: the newer nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Arthritis; Aspirin; Diclofenac; Humans; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone; Phenylbutyrates; Piroxicam; Propionates; Sulindac; Thiazines | 1982 |
Diclofenac sodium: a review of its pharmacological properties and therapeutic use in rheumatic diseases and pain of varying origin.
Topics: Adult; Animals; Arthritis, Rheumatoid; Aspirin; Cyclooxygenase Inhibitors; Diclofenac; Drug Interactions; Female; Gastric Mucosa; Gout; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Osteoarthritis; Pain; Phenylacetates; Platelet Aggregation; Rheumatic Diseases; Spondylitis, Ankylosing; Ulcer | 1980 |
Current status of the etiology and management of dysmenorrhea in adolescence.
Topics: Adolescent; Aspirin; Contraceptives, Oral; Cyclooxygenase Inhibitors; Dysmenorrhea; Female; Humans; Ibuprofen; Indomethacin; Naproxen; ortho-Aminobenzoates; Ovulation; Prostaglandin Antagonists; Prostaglandins; Uterine Contraction | 1982 |
Nonsteroidal antiinflammatory drugs (second of two parts).
Topics: Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Fenoprofen; Humans; Ibuprofen; Mefenamic Acid; Naproxen; Propionates; Sulindac; Tolmetin | 1980 |
Primary dysmenorrhea treatment with prostaglandin inhibitors: a review.
Topics: Adolescent; Adult; Dysmenorrhea; Female; Humans; Ibuprofen; Indomethacin; Middle Aged; Naproxen; ortho-Aminobenzoates; Phenylbutazone; Prostaglandin Antagonists | 1981 |
['Stomach-friendly' NSAIDs: careful optimism?].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Butanones; Gastritis; Humans; Ibuprofen; Misoprostol; Nabumetone; Naproxen; Randomized Controlled Trials as Topic; Risk Factors; Stomach Ulcer | 1995 |
Nonsteroidal antiinflammatory drugs in menorrhagia.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Danazol; Female; Humans; Ibuprofen; Mefenamic Acid; Menorrhagia; Naproxen | 1993 |
Use of carprofen for the treatment of pain and inflammation in dogs.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carbazoles; Clonixin; Cyclooxygenase Inhibitors; Dog Diseases; Dogs; Ibuprofen; Indomethacin; Ketoprofen; Meclofenamic Acid; Meloxicam; Naproxen; Osteoarthritis; Pain; Phenylbutazone; Piroxicam; Thiazines; Thiazoles | 1997 |
Efficacy of minor analgesics in primary dysmenorrhoea: a systematic review.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dysmenorrhea; Female; Humans; Ibuprofen; Mefenamic Acid; Middle Aged; Naproxen; Randomized Controlled Trials as Topic | 1998 |
Non-NSAID pharmacologic treatment options for the management of chronic pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dextropropoxyphene; Humans; Ibuprofen; Naproxen; Osteoarthritis; Pain; Tramadol; Treatment Outcome | 1998 |
Acute nonoliguric renal failure in children associated with nonsteroidal antiinflammatory agents.
Topics: Acute Kidney Injury; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Child, Preschool; Female; Humans; Ibuprofen; Male; Naproxen; Nonprescription Drugs; Oliguria; Pyelonephritis; Risk Factors | 1998 |
[Brufen on the eve of the 21st century].
Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Gout Suppressants; Humans; Ibuprofen; Middle Aged; Naproxen; Osteoarthritis; Piroxicam; Retrospective Studies; Rheumatic Diseases; Time Factors | 1998 |
Distribution and expression of cyclooxygenase (COX) isoenzymes, their physiological roles, and the categorization of nonsteroidal anti-inflammatory drugs (NSAIDs).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Controlled Clinical Trials as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Etodolac; Gene Expression; Humans; Ibuprofen; Indomethacin; Isoenzymes; Meloxicam; Membrane Proteins; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Thiazines; Thiazoles | 1999 |
Celecoxib clinical profile.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cardiovascular Diseases; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Humans; Ibuprofen; In Vitro Techniques; Isoenzymes; Kidney Diseases; Membrane Proteins; Middle Aged; Naproxen; Osteoarthritis; Pain; Peptic Ulcer; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Randomized Controlled Trials as Topic; Sulfonamides; Treatment Outcome | 2000 |
[Meta-analysis on the effect and adverse reaction on patients with osteoarthritis and rheumatoid arthritis treated with non-steroidal anti-inflammatory drugs].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; China; Diclofenac; Humans; Ibuprofen; Meloxicam; Nabumetone; Naproxen; Osteoarthritis; Oxaprozin; Propionates; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiazoles | 2003 |
Migraine headache.
Topics: Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Diclofenac; Drug Therapy, Combination; Ergotamine; Humans; Ibuprofen; Indoles; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Oxazolidinones; Piperidines; Pyrrolidines; Salicylates; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines | 2003 |
Migraine headache.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ergotamine; Humans; Ibuprofen; Indoles; Migraine Disorders; Naproxen; ortho-Aminobenzoates; Oxazolidinones; Piperidines; Pyrrolidines; Salicylates; Sumatriptan; Triazoles; Tryptamines | 2004 |
Ulcers, Helicobacter pylori infection, platelets and gastrointestinal complications of non-steroidal anti-inflammatory drugs: what are the connections?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Cyclooxygenase Inhibitors; Diclofenac; Gastrointestinal Hemorrhage; Helicobacter Infections; Humans; Ibuprofen; Lactones; Naproxen; Peptic Ulcer; Risk Factors; Sulfones | 2002 |
Non-steroidal antiinflammatory drugs and the risk of acute myocardial infarction.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Cohort Studies; Diclofenac; Dose-Response Relationship, Drug; Humans; Ibuprofen; Lactones; Myocardial Infarction; Naproxen; Risk Factors; Sulfones | 2006 |
Primary dysmenorrhea: advances in pathogenesis and management.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Contraceptives, Oral, Combined; Decision Trees; Dysmenorrhea; Female; Humans; Ibuprofen; Ketoprofen; Naproxen | 2006 |
[Are the NSAIDs able to compromising the cardio-preventive efficacy of aspirin?].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Clopidogrel; Cohort Studies; Cyclooxygenase Inhibitors; Drug Interactions; Follow-Up Studies; Humans; Ibuprofen; MEDLINE; Middle Aged; Multivariate Analysis; Naproxen; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk; Thromboxane B2; Ticlopidine; Time Factors | 2006 |
Is any one analgesic superior for episodic tension-type headache?
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diclofenac; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Ibuprofen; Ketoprofen; Naproxen; Nonprescription Drugs; Secondary Prevention; Tension-Type Headache; Treatment Outcome | 2006 |
[A novel class of anti-inflammatory and analgesic drugs--NO-donating NSAIDs].
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiotonic Agents; Cyclooxygenase Inhibitors; Flurbiprofen; Gastrointestinal Diseases; Humans; Ibuprofen; Naproxen; Nitrates; Nitric Oxide Donors | 2007 |
Interventions for pain with intrauterine device insertion.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Intrauterine Devices; Misoprostol; Naproxen; Oxytocics; Pain; Randomized Controlled Trials as Topic | 2009 |
Cardiovascular risk with non-steroidal anti-inflammatory drugs: systematic review of population-based controlled observational studies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Diclofenac; Humans; Ibuprofen; Naproxen | 2011 |
Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Vessels; Coronary Disease; Cyclooxygenase 2 Inhibitors; Diclofenac; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; Ibuprofen; Myocardial Infarction; Naproxen; Stroke; Vascular Diseases | 2013 |
What's new in NSAID pharmacotherapy: oral agents to injectables.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Humans; Hyaluronic Acid; Hydrogen Sulfide; Ibuprofen; Injections; Injections, Intra-Articular; Isoxazoles; Nanoparticles; Naproxen; Nitric Oxide Donors; Vasodilator Agents | 2013 |
Comparative effectiveness of pharmacologic interventions for knee osteoarthritis: a systematic review and network meta-analysis.
Topics: Acetaminophen; Adrenal Cortex Hormones; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Hyaluronic Acid; Ibuprofen; Injections, Intra-Articular; Naproxen; Osteoarthritis, Knee; Pain; Pyrazoles; Sulfonamides; Treatment Outcome; Viscosupplements | 2015 |
[Cardiovascular side effects of non-steroidal anti-inflammatory drugs in the light of recent recommendations. Diclofenac is not more dangerous].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Cardiovascular System; Diclofenac; Drug Interactions; Humans; Ibuprofen; Naproxen | 2015 |
Interventions for pain with intrauterine device insertion.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Intrauterine Devices; Lidocaine; Misoprostol; Naproxen; Oxytocics; Pain; Prilocaine; Randomized Controlled Trials as Topic | 2015 |
Ibuprofen for acute treatment of episodic tension-type headache in adults.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Cyclooxygenase Inhibitors; Diclofenac; Humans; Ibuprofen; Ketoprofen; Naproxen; Numbers Needed To Treat; Pain Measurement; Piroxicam; Randomized Controlled Trials as Topic; Tension-Type Headache; Time Factors | 2015 |
Nonaspirin Nonsteroidal Anti-Inflammatory Drugs and Risk of Hemorrhagic Stroke: A Systematic Review and Meta-Analysis of Observational Studies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cerebral Hemorrhage; Diclofenac; Humans; Ibuprofen; Incidence; Indomethacin; Lactones; Meloxicam; Naproxen; Observational Studies as Topic; Odds Ratio; Piroxicam; Proportional Hazards Models; Stroke; Sulfones; Thiazines; Thiazoles | 2016 |
Nonsteroidal Anti-inflammatory Drugs for Managing Postoperative Endodontic Pain in Patients Who Present with Preoperative Pain: A Systematic Review and Meta-analysis.
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Naproxen; Pain, Postoperative; Root Canal Therapy; Toothache | 2017 |
Non-steroidal anti-inflammatory drugs (NSAIDs) for chronic non-cancer pain in children and adolescents.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Arthritis, Rheumatoid; Aspirin; Celecoxib; Child; Child, Preschool; Chronic Disease; Chronic Pain; Fenoprofen; Humans; Ibuprofen; Lactones; Meloxicam; Methoxsalen; Naproxen; Randomized Controlled Trials as Topic; Sulfones; Thiazines; Thiazoles | 2017 |
Cardiorenal Safety of OTC Analgesics.
Topics: Acetaminophen; Analgesics; Drug Labeling; Heart Diseases; Humans; Ibuprofen; Kidney Diseases; Naproxen; Nonprescription Drugs; Patient Safety; Risk Assessment; Risk Factors | 2018 |
[Cardiovascular risk of non-steroidal anti-inflammatory drugs].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Celecoxib; Drug Interactions; Humans; Ibuprofen; Naproxen; Risk Factors | 2018 |
Efficacy and safety of over-the-counter analgesics for primary dysmenorrhea: A network meta-analysis.
Topics: Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Dysmenorrhea; Female; Humans; Ibuprofen; Ketoprofen; Middle Aged; Naproxen; Network Meta-Analysis; Nonprescription Drugs; Treatment Outcome; Young Adult | 2020 |
Toxicity of the Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) acetylsalicylic acid, paracetamol, diclofenac, ibuprofen and naproxen towards freshwater invertebrates: A review.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Ecosystem; Fresh Water; Humans; Ibuprofen; Invertebrates; Naproxen | 2020 |
Occurrence and ecotoxicological risk assessment of non-steroidal anti-inflammatory drugs in South African aquatic environment: What is known and the missing information?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Environmental Monitoring; Humans; Ibuprofen; Naproxen; Pharmaceutical Preparations; Risk Assessment; Water Pollutants, Chemical | 2021 |
Metabolism of non-steroidal anti-inflammatory drugs by non-target wild-living organisms.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Naproxen; Pharmaceutical Preparations | 2021 |
Recent Advances in the Synthesis of Ibuprofen and Naproxen.
Topics: Electrochemistry; Humans; Hydrogenation; Ibuprofen; Naproxen; Oxidation-Reduction; Stereoisomerism | 2021 |
A review on environmental occurrence, toxicity and microbial degradation of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Naproxen; Phanerochaete; Pharmaceutical Preparations; Water Pollutants, Chemical | 2021 |
Pharmaceuticals as emerging pollutants: Case naproxen an overview.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Environmental Pollutants; Ibuprofen; Naproxen; Pharmaceutical Preparations; Water Pollutants, Chemical | 2022 |
Systematic review and meta-analysis of studies in which burrowing behaviour was assessed in rodent models of disease-associated persistent pain.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Celecoxib; Disease Models, Animal; Gabapentin; Ibuprofen; Male; Naproxen; Pain; Rats; Rodentia | 2022 |
Lessons from 20 years with COX-2 inhibitors: Importance of dose-response considerations and fair play in comparative trials.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Fibrinolytic Agents; Humans; Ibuprofen; Lactones; Naproxen; Prostaglandins; Prostaglandins I; Sulfones; Thromboxanes | 2022 |
Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine-device use.
Topics: Acetaminophen; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Dysmenorrhea; Female; Humans; Ibuprofen; Intrauterine Devices, Medicated; Mefenamic Acid; Menorrhagia; Middle Aged; Naproxen; Thiamine; Tranexamic Acid; Young Adult | 2022 |
Efficacy and Safety of NSAIDs in Infants: A Comprehensive Review of the Literature of the Past 20 Years.
Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Child; Chronic Disease; Diclofenac; Flurbiprofen; Humans; Ibuprofen; Infant; Ketoprofen; Ketorolac; Meloxicam; Naproxen; Niflumic Acid; Pain | 2022 |
Recommendations for the Use of Nonsteroidal Anti-inflammatory Drugs and Cardiovascular Disease Risk: Decades Later, Any New Lessons Learned?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Humans; Ibuprofen; Naproxen | 2023 |
Pharmacokinetic and pharmacodynamic herb-drug interactions of common over-the-counter pain medications.
Topics: Acetaminophen; Aspirin; Herb-Drug Interactions; Humans; Ibuprofen; Naproxen; Pain | 2023 |
Occurrence, toxicity, impact and removal of selected non-steroidal anti-inflammatory drugs (NSAIDs): A review.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Ibuprofen; Naproxen; Wastewater; Water; Water Pollutants, Chemical | 2023 |
73 trial(s) available for ibuprofen and naproxen
| Article | Year |
|---|---|
Prostaglandin synthetase inhibitors and dysmenorrhea. A survey and personal clinical experience.
Topics: Adolescent; Adult; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Evaluation; Dysmenorrhea; Female; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Naproxen; ortho-Aminobenzoates; Placebos; Prostaglandin Antagonists | 1979 |
Drug trial in rheumatoid arthritis: a new design.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Humans; Ibuprofen; Male; Mathematics; Middle Aged; Naproxen; Research Design | 1978 |
Hypersensitivity to five non-steroidal anti-inflammatory agents: ibuprofen, fenoprofen, indomethacin, naproxen and tolmetin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Drug Hypersensitivity; Fenoprofen; Humans; Ibuprofen; Indomethacin; Iodides; Naproxen; Tolmetin | 1978 |
A review of upper-gastrointestinal effects of the newer nonsteroidal antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Evaluation; Fenoprofen; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Ibuprofen; Ketoprofen; Naproxen; Phenylbutazone; Registries; Sulindac; Tolmetin | 1979 |
The effects of ibuprofen, indomethacin, aspirin, naproxen, and placebo on the gastric mucosa of normal volunteers: a gastroscopic and photographic study.
Topics: Adult; Aspirin; Gastric Mucosa; Gastroscopy; Humans; Ibuprofen; Indomethacin; Middle Aged; Naproxen; Placebos | 1979 |
Four new anti-inflammatory drugs: responses and variations.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Fenoprofen; Gastrointestinal Diseases; Humans; Ibuprofen; Ketoprofen; Naproxen; Pain | 1976 |
Visual analogue scales for endoscopic evaluation of nonsteroidal anti-inflammatory drug-induced mucosal damage in the stomach and duodenum.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Duodenal Diseases; Duodenoscopy; Duodenum; Gastric Mucosa; Gastroscopy; Humans; Ibuprofen; Intestinal Mucosa; Male; Middle Aged; Naproxen; Observer Variation; Stomach Diseases | 1990 |
Ibuprofen and naproxen-sodium in the treatment of primary dysmenorrhea: a double-blind cross-over study.
Topics: Adolescent; Adult; Double-Blind Method; Dysmenorrhea; Female; Humans; Ibuprofen; Naproxen; Pain | 1985 |
An endoscopic comparison of the effects of etodolac, indomethacin, ibuprofen, naproxen, and placebo on the gastrointestinal mucosa.
Topics: Acetates; Adolescent; Adult; Endoscopy; Etodolac; Gastric Mucosa; Humans; Ibuprofen; Indomethacin; Intestinal Mucosa; Middle Aged; Naproxen; Placebos | 1987 |
Four popular anti-inflammatories. Which?
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Drug Evaluation; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Piroxicam; Random Allocation | 1988 |
Nabumetone in the treatment of skin and soft tissue injury.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Clinical Trials as Topic; Double-Blind Method; Edema; Female; Humans; Ibuprofen; Joints; Male; Middle Aged; Nabumetone; Naproxen; Pain; Random Allocation; Skin; Sprains and Strains | 1987 |
International experience with diclofenac in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Humans; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone | 1986 |
International experiences with diclofenac in osteoarthritis.
Topics: Aspirin; Clinical Trials as Topic; Diclofenac; Diflunisal; Double-Blind Method; Gastrointestinal Diseases; Humans; Ibuprofen; Indomethacin; Naproxen; Osteoarthritis; Random Allocation; Sulindac | 1986 |
Worldwide safety experience with diclofenac.
Topics: Adult; Aged; Aspirin; Chemical and Drug Induced Liver Injury; Child; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Female; Gastrointestinal Diseases; Gastroscopy; Humans; Ibuprofen; Kidney Diseases; Middle Aged; Naproxen; Occult Blood; Piroxicam; Thiazines | 1986 |
Clinical benefits and comparative safety of piroxicam. Analysis of worldwide clinical trials data.
Topics: Adult; Age Factors; Aged; Clinical Trials as Topic; Female; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Information Systems; Male; Middle Aged; Naproxen; Norway; Osteoarthritis; Peptic Ulcer; Piroxicam; Product Surveillance, Postmarketing; United Kingdom | 1986 |
Effects of ibuprofen, naproxen, and sulindac on prostaglandins in men.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Furosemide; Humans; Ibuprofen; Indenes; Kidney; Male; Naproxen; Prostaglandins; Random Allocation; Renin; Sulindac; Thromboxanes | 1985 |
Relief of morning stiffness: a comparative study of naproxen and ibuprofen.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Random Allocation; Time Factors | 1985 |
Four-way, multicenter, crossover trial of ibuprofen, fenoprofen calcium, naproxen, and tolmetin sodium in osteoarthritis: comparative clinical profiles.
Topics: Adult; Aged; Aspirin; Clinical Trials as Topic; Double-Blind Method; Drug Tolerance; Female; Fenoprofen; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis; Phenylpropionates; Pyrroles; Tolmetin | 1983 |
New peripherally-acting oral analgesic agents.
Topics: Administration, Oral; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Diflunisal; Humans; Ibuprofen; Indoprofen; Naproxen; Pain; Pain, Postoperative; Tolmetin | 1983 |
A multi-centre study of tiaprofenic acid ('Surgam') and five comparative drugs in rheumatoid arthritis and osteoarthritis in general practice.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Osteoarthritis; Patient Compliance; Propionates; Sex Factors; Thiazines | 1983 |
A study of naproxen and ibuprofen in patients with osteoarthritis seen in general practice. The Manchester General Practitioner Group.
Topics: Aged; Clinical Trials as Topic; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis | 1984 |
Review of ibuprofen for osteoarthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Meclofenamic Acid; Naproxen; Osteoarthritis; Phenylbutazone; Sulindac; Tolmetin | 1984 |
Update on ibuprofen for rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Piroxicam; Sulindac; Thiazines; Tolmetin | 1984 |
Effect of ibuprofen, naproxen sodium and paracetamol on intrauterine pressure and menstrual pain in dysmenorrhoea.
Topics: Acetaminophen; Adult; Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea; Female; Humans; Ibuprofen; Naproxen; Pain; Pressure; Uterus | 1984 |
Effect of different prostaglandin synthesis inhibitors on post-occlusive blood flow in human forearm.
Topics: Adolescent; Adult; Aspirin; Cyclooxygenase Inhibitors; Diclofenac; Female; Forearm; Humans; Hyperemia; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Piroxicam; Regional Blood Flow; Thiazines | 1983 |
Prostaglandin synthetase inhibitors in the treatment of primary dysmenorrhea. Outcome trials reviewed.
Topics: Clinical Trials as Topic; Cyclooxygenase Inhibitors; Dysmenorrhea; Female; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Naproxen | 1984 |
Endoscopic studies of gastric and duodenal injury after the use of ibuprofen, aspirin, and other nonsteroidal anti-inflammatory agents.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Aspirin; Buffers; Duodenum; Endoscopy; Female; Gastric Mucosa; Humans; Ibuprofen; Indomethacin; Intestinal Mucosa; Male; Middle Aged; Naproxen; Time Factors; Tolmetin | 1984 |
Differential effects of ibuprofen and naproxen sodium on menstrual prostaglandin release and on prostaglandin production in the rat uterine homogenate.
Topics: Animals; Cell-Free System; Dysmenorrhea; Female; Humans; Ibuprofen; Menstruation; Naproxen; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Uterus | 1984 |
Comparison of the analgesic effect of ten nonsteroidal anti-inflammatory drugs.
Topics: Adult; Aged; Analgesics; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Carbazoles; Diclofenac; Female; Humans; Ibuprofen; Indomethacin; Ketoprofen; Male; Middle Aged; Naproxen; ortho-Aminobenzoates; Quinazolines | 1984 |
Anti-rheumatic efficacy of naproxen.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Digestive System; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen | 1982 |
Double-blind evaluation of naproxen and ibuprofen in periodontal surgery.
Topics: Acetaminophen; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Gingivectomy; Humans; Ibuprofen; Male; Naproxen; Pain, Postoperative; Placebos | 1980 |
Arthritis: anti-inflammatory drugs in practice.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Apazone; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Fenoprofen; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis; Random Allocation | 1981 |
A comparative endoscopic evaluation of the damaging effects of nonsteroidal anti-inflammatory agents on the gastric and duodenal mucosa.
Topics: Adult; Anti-Inflammatory Agents; Duodenum; Endoscopy; Gastric Mucosa; Humans; Ibuprofen; Indomethacin; Intestinal Mucosa; Middle Aged; Naproxen; Tolmetin | 1981 |
Naproxen suppositories in combination with oral naproxen, indomethacin and ibuprofen in the treatment of rheumatoid arthritis.
Topics: Administration, Oral; Adult; Aged; Arthritis, Rheumatoid; Drug Therapy, Combination; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Suppositories | 1980 |
Comparison ketoprofen, ibuprofen and naproxen sodium in the treatment of tension-type headache.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Ibuprofen; Ketoprofen; Male; Middle Aged; Naproxen; Pain Measurement; Prospective Studies; Tension-Type Headache | 1995 |
The effects of nonsteroidal anti-inflammatory drugs on blood pressures of patients with hypertension controlled by verapamil.
Topics: Adolescent; Adult; Aged; Blood Pressure; Double-Blind Method; Drug Interactions; Female; Humans; Hypertension; Ibuprofen; Male; Middle Aged; Naproxen; Verapamil | 1995 |
Assessment of blood pressure during treatment with naproxen or ibuprofen in hypertensive patients treated with hydrochlorothiazide.
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Diastole; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Ibuprofen; Male; Middle Aged; Naproxen; Time Factors | 1993 |
Safety experience with nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in osteoarthritis and rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Diclofenac; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Piroxicam | 1993 |
Efficacy and safety of nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in the elderly.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Diclofenac; Female; Humans; Ibuprofen; Male; Nabumetone; Naproxen; Osteoarthritis; Piroxicam | 1993 |
Efficacy of nabumetone versus diclofenac, naproxen, ibuprofen, and piroxicam in osteoarthritis and rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Diclofenac; Female; Humans; Ibuprofen; Life Style; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; Piroxicam | 1993 |
Nonsteroidal anti-inflammatory drug use in relation to major upper gastrointestinal bleeding.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Diclofenac; Female; Gastrointestinal Hemorrhage; Humans; Hungary; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Piroxicam; Risk Factors; Sweden; United States | 1993 |
[Management of postoperative pain in stomatology with ibuprofen L-arginine and naproxen].
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Female; Humans; Ibuprofen; Informed Consent; Male; Middle Aged; Molar, Third; Naproxen; Pain, Postoperative; Tooth Extraction | 1998 |
Comparative inhibitory activity of rofecoxib, meloxicam, diclofenac, ibuprofen, and naproxen on COX-2 versus COX-1 in healthy volunteers.
Topics: Adolescent; Adult; Bleeding Time; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Female; Humans; Ibuprofen; Isoenzymes; Lactones; Lipopolysaccharides; Meloxicam; Membrane Proteins; Middle Aged; Naproxen; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sulfones; Thiazines; Thiazoles; Thromboxane B2 | 2000 |
The optimal analgesic dose of rofecoxib: Overview of six randomized controlled trials.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Ibuprofen; Isoenzymes; Lactones; Male; Membrane Proteins; Middle Aged; Molar, Third; Naproxen; Pain Measurement; Pain, Postoperative; Proportional Hazards Models; Prostaglandin-Endoperoxide Synthases; Statistics, Nonparametric; Sulfones; Survival Analysis; Time Factors; Tooth Extraction | 2000 |
Pharmacokinetics, safety, and tolerability of BAY 12-9566 and nonsteroidal anti-inflammatory agents (naproxen, ibuprofen) during coadministration in patients with osteoarthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Area Under Curve; Biphenyl Compounds; Chromatography, High Pressure Liquid; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Metalloendopeptidases; Middle Aged; Naproxen; Organic Chemicals; Osteoarthritis; Phenylbutyrates | 2001 |
Comparison of the efficacy and safety of nonprescription doses of naproxen and naproxen sodium with ibuprofen, acetaminophen, and placebo in the treatment of primary dysmenorrhea: a pooled analysis of five studies.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Tolerance; Dysmenorrhea; Female; Humans; Ibuprofen; Naproxen; Nonprescription Drugs; Pain; Time Factors; Treatment Outcome | 2002 |
A randomized, controlled comparison of ibuprofen at the maximal over-the-counter dose compared with prescription-dose celecoxib on upper gastrointestinal mucosal injury.
Topics: Adolescent; Adult; Aged; Celecoxib; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Endoscopy, Gastrointestinal; Female; Gastric Mucosa; Humans; Ibuprofen; Intestinal Mucosa; Male; Maximum Tolerated Dose; Middle Aged; Naproxen; Nonprescription Drugs; Probability; Pyrazoles; Reference Values; Risk Assessment; Sensitivity and Specificity; Sulfonamides | 2004 |
Therapeutic arthritis research and gastrointestinal event trial of lumiracoxib - study design and patient demographics.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Health Status; Humans; Ibuprofen; Isoenzymes; Membrane Proteins; Middle Aged; Naproxen; Organic Chemicals; Osteoarthritis; Peptic Ulcer; Prognosis; Prostaglandin-Endoperoxide Synthases; Risk Factors | 2004 |
Comparison of the analgesic efficacy and safety of nonprescription doses of naproxen sodium and Ibuprofen in the treatment of osteoarthritis of the knee.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Double-Blind Method; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis, Knee; Pain Measurement; Quality of Life; Treatment Outcome | 2004 |
A randomized open label study of pain medications (naproxen, acetaminophen and ibuprofen) for controlling side effects during initiation of IFN beta-1a therapy and during its ongoing use for relapsing-remitting multiple sclerosis.
Topics: Acetaminophen; Adjuvants, Immunologic; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combination; Fatigue; Female; Humans; Ibuprofen; Interferon beta-1a; Interferon-beta; Male; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Naproxen; Pain; Prospective Studies | 2004 |
Pain control during fixed orthodontic appliance therapy.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Facial Pain; Female; Flurbiprofen; Humans; Ibuprofen; Male; Naproxen; Orthodontic Appliances; Orthodontics, Corrective; Pain Measurement; Prospective Studies; Surveys and Questionnaires | 2005 |
Valdecoxib is associated with improved dyspepsia-related health compared with nonspecific NSAIDs in patients with osteoarthritis or rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Dyspepsia; Female; Humans; Ibuprofen; Isoxazoles; Male; Middle Aged; Naproxen; Osteoarthritis; Pain Measurement; Patient Satisfaction; Placebos; Quality of Life; Sulfonamides; Treatment Outcome; Upper Gastrointestinal Tract | 2005 |
Effects of preoperative ibuprofen and naproxen sodium on orthodontic pain.
Topics: Adolescent; Analgesics, Non-Narcotic; Analysis of Variance; Dose-Response Relationship, Drug; Facial Pain; Female; Humans; Ibuprofen; Male; Naproxen; Orthodontic Appliances; Orthodontics, Corrective; Pain Measurement; Pain, Postoperative; Preoperative Care; Prospective Studies; Surveys and Questionnaires | 2005 |
Cardiovascular outcomes in high risk patients with osteoarthritis treated with ibuprofen, naproxen or lumiracoxib.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Female; Heart Defects, Congenital; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis | 2007 |
Effect of risk factors on complicated and uncomplicated ulcers in the TARGET lumiracoxib outcomes study.
Topics: Age Distribution; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Diclofenac; Duodenal Ulcer; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis; Risk Factors; Risk Reduction Behavior; Stomach Ulcer | 2007 |
Clinical trial: comparison of the gastrointestinal safety of lumiracoxib with traditional nonselective nonsteroidal anti-inflammatory drugs early after the initiation of treatment--findings from the Therapeutic Arthritis Research and Gastrointestinal Even
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Statistics as Topic | 2008 |
A comparison of the blood pressure changes of lumiracoxib with those of ibuprofen and naproxen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Creatinine; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Pain Measurement | 2008 |
Rationale, design, and governance of Prospective Randomized Evaluation of Celecoxib Integrated Safety versus Ibuprofen Or Naproxen (PRECISION), a cardiovascular end point trial of nonsteroidal antiinflammatory agents in patients with arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cardiovascular Diseases; Celecoxib; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Follow-Up Studies; Humans; Ibuprofen; Middle Aged; Naproxen; Prospective Studies; Pyrazoles; Sulfonamides; Treatment Outcome | 2009 |
Effects of analgesics on orthodontic pain.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Double-Blind Method; Female; Follow-Up Studies; Humans; Ibuprofen; Male; Mastication; Naproxen; Orthodontic Appliances; Pain; Pain Measurement; Placebos; Premedication; Prospective Studies; Time Factors; Treatment Outcome; Young Adult | 2011 |
Effects of three oral analgesics on postoperative pain following root canal preparation: a controlled clinical trial.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Double-Blind Method; Drug Combinations; Female; Follow-Up Studies; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Pain Measurement; Pain, Postoperative; Placebos; Pulpectomy; Pulpitis; Root Canal Preparation; Tramadol; Young Adult | 2012 |
Responsiveness of the OARSI-OMERACT osteoarthritis pain and function measures.
Topics: Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Disability Evaluation; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Nitric Oxide Donors; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain; Pain Measurement; Severity of Illness Index; Treatment Outcome | 2012 |
Interference of NSAIDs with the thrombocyte inhibitory effect of aspirin: a placebo-controlled, ex vivo, serial placebo-controlled serial crossover study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Administration Schedule; Drug Interactions; Etoricoxib; Female; Humans; Ibuprofen; Male; Meloxicam; Middle Aged; Naproxen; Netherlands; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Pyridines; Risk Assessment; Sulfones; Thiazines; Thiazoles; Time Factors; Young Adult | 2013 |
NSAIDs are associated with lower depression scores in patients with osteoarthritis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Depression; Double-Blind Method; Drug Administration Schedule; Female; Humans; Ibuprofen; Logistic Models; Male; Middle Aged; Multivariate Analysis; Naproxen; Osteoarthritis; Psychological Tests; Pyrazoles; Sulfonamides; Surveys and Questionnaires; Treatment Outcome | 2013 |
Assessment of common nonsteroidal anti-inflammatory medications by whole blood aggregometry: a clinical evaluation for the perioperative setting.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Loss, Surgical; Celecoxib; Cyclooxygenase Inhibitors; Female; Healthy Volunteers; Humans; Ibuprofen; Male; Meloxicam; Middle Aged; Naproxen; Perioperative Care; Platelet Aggregation; Pyrazoles; Sulfonamides; Thiazines; Thiazoles; Young Adult | 2014 |
Analgesic Efficacy of a New Immediate-Release/Extended-Release Formulation of Ibuprofen: Results From Single- and Multiple-Dose Postsurgical Dental Pain Studies.
Topics: Adolescent; Adult; Analgesics; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Ibuprofen; Male; Naproxen; Tablets; Tooth Extraction; Toothache; Treatment Outcome; Young Adult | 2017 |
Cardiovascular Safety of Celecoxib, Naproxen, or Ibuprofen for Arthritis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cardiovascular Diseases; Celecoxib; Cyclooxygenase 2 Inhibitors; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Intention to Treat Analysis; Kidney Diseases; Male; Middle Aged; Naproxen; Risk | 2016 |
Topics: Adult; Arthritis, Rheumatoid; Cardiovascular Diseases; Celecoxib; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Naproxen; Osteoarthritis; Proton Pump Inhibitors; Survival Analysis; United States; United States Food and Drug Administration | 2017 |
The Risk of Major NSAID Toxicity with Celecoxib, Ibuprofen, or Naproxen: A Secondary Analysis of the PRECISION Trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis | 2017 |
Differential blood pressure effects of ibuprofen, naproxen, and celecoxib in patients with arthritis: the PRECISION-ABPM (Prospective Randomized Evaluation of Celecoxib Integrated Safety Versus Ibuprofen or Naproxen Ambulatory Blood Pressure Measurement)
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Blood Pressure; Celecoxib; Coronary Artery Disease; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Hypertension; Ibuprofen; Male; Naproxen; Osteoarthritis; Prospective Studies | 2017 |
Differences in Safety of Nonsteroidal Antiinflammatory Drugs in Patients With Osteoarthritis and Patients With Rheumatoid Arthritis: A Randomized Clinical Trial.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cardiovascular Diseases; Celecoxib; Double-Blind Method; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Kidney Diseases; Male; Middle Aged; Naproxen; Osteoarthritis; Risk Factors; Treatment Outcome | 2018 |
Randomised clinical trial: gastrointestinal events in arthritis patients treated with celecoxib, ibuprofen or naproxen in the PRECISION trial.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, Rheumatoid; Aspirin; Celecoxib; Double-Blind Method; Drug Therapy, Combination; Esomeprazole; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis; Treatment Outcome | 2018 |
Derivation and Validation of a Major Toxicity Risk Score Among Nonsteroidal Antiinflammatory Drug Users Based on Data From a Randomized Controlled Trial.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cardiovascular Diseases; Celecoxib; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis; Reproducibility of Results; Risk Assessment; Risk Factors | 2019 |
Cardiorenal risk of celecoxib compared with naproxen or ibuprofen in arthritis patients: insights from the PRECISION trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cardiovascular Diseases; Celecoxib; Humans; Ibuprofen; Naproxen; Prospective Studies | 2022 |
545 other study(ies) available for ibuprofen and naproxen
| Article | Year |
|---|---|
Synthesis and antiinflammatory activity of cis-4,5,6,7,8,8a,9-hexahydro-alpha-methyl-5H-fluorene-2-acetic acid.
Topics: Animals; Anti-Inflammatory Agents; Arthus Reaction; Edema; Fluorenes; Magnetic Resonance Spectroscopy; Molecular Conformation; Rabbits; Rats; Stereoisomerism | 1977 |
Antinociceptive (aminoalkyl)indoles.
Topics: Analgesia; Analgesics; Animals; Chemical Phenomena; Chemistry; Cyclooxygenase Inhibitors; Indoles; Magnetic Resonance Spectroscopy; Male; Methylation; Mice; Molecular Conformation; Molecular Structure; Muscle Contraction; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Vas Deferens | 1991 |
1,2-Dihydro-1-oxopyrrolo[3,2,1-kl]phenothiazine-2-carboxamides and congeners, dual cyclooxygenase/5-lipoxygenase inhibitors with antiinflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cell Line; Cyclooxygenase Inhibitors; Edema; Indicators and Reagents; Lipoxygenase Inhibitors; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Models, Molecular; Molecular Structure; Prostaglandin Antagonists; Pyrroles; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thiazines | 1990 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Synthesis and antiinflammatory activity of hexahydrothiopyrano[4,3-c]pyrazoles and related analogues.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthus Reaction; Chemical Phenomena; Chemistry; Edema; Guinea Pigs; Hypersensitivity, Delayed; Male; Mice; Pyrazoles; Rats; Rats, Inbred Lew; Rats, Inbred Strains | 1982 |
Nonsteroidal antiinflammatory agents. 14. Synthesis and pharmacological profile of 6-chloro-5-(cyclopentylmethyl)indan-1-carboxylic acid.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Edema; Indans; Indenes; Male; Rats; Rats, Inbred Strains | 1984 |
Effect of structural change on acute toxicity and antiinflammatory activity in a series of imidazothiazoles and thiazolobenzimidazoles.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Chemical Phenomena; Chemistry; Imidazoles; Lethal Dose 50; Locomotion; Male; Mice; Muscle Tonus; Nervous System; Orientation; Rats; Structure-Activity Relationship; Thiazoles | 1981 |
Antiinflammatory 4,5-diarylpyrroles. 2. Activity as a function of cyclooxygenase-2 inhibition.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Pyrroles; Rats; Structure-Activity Relationship | 1995 |
Synthesis and antiinflammatory activity of certain 5,6,7,8-tetrahydroquinolines and related compounds.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Female; Male; Quinolines; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Rats, Wistar | 1995 |
Nonsteroidal anti-inflammatory drugs as scaffolds for the design of 5-lipoxygenase inhibitors.
Topics: Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Drug Design; Humans; Hydroxyurea; Ibuprofen; Indomethacin; Leukocytes; Leukotriene E4; Lipoxygenase Inhibitors; Magnetic Resonance Spectroscopy; Male; Naproxen; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Tumor Cells, Cultured | 1997 |
Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis.
Topics: Animals; Biological Assay; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Kinetics; Placenta; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sheep | 1998 |
New cyclooxygenase-2/5-lipoxygenase inhibitors. 1. 7-tert-buty1-2,3-dihydro-3,3-dimethylbenzofuran derivatives as gastrointestinal safe antiinflammatory and analgesic agents: discovery and variation of the 5-keto substituent.
Topics: Animals; Anti-Inflammatory Agents; Benzofurans; Blood Platelets; Carrageenan; Cyclooxygenase Inhibitors; Edema; Humans; Lipoxygenase Inhibitors; Male; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley | 1998 |
New cyclooxygenase-2/5-lipoxygenase inhibitors. 2. 7-tert-butyl-2,3-dihydro-3,3-dimethylbenzofuran derivatives as gastrointestinal safe antiinflammatory and analgesic agents: variations of the dihydrobenzofuran ring.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzofurans; Blood Platelets; Carrageenan; Cyclooxygenase Inhibitors; Edema; Humans; Lipoxygenase Inhibitors; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley | 1998 |
New cyclooxygenase-2/5-lipoxygenase inhibitors. 3. 7-tert-butyl-2, 3-dihydro-3,3-dimethylbenzofuran derivatives as gastrointestinal safe antiinflammatory and analgesic agents: variations at the 5 position.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Edema; Enzyme Inhibitors; Humans; Isoenzymes; Lipoxygenase Inhibitors; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Structure-Activity Relationship | 1998 |
Ursolic acid from Plantago major, a selective inhibitor of cyclooxygenase-2 catalyzed prostaglandin biosynthesis.
Topics: Animals; Cattle; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; In Vitro Techniques; Isoenzymes; Plantago; Plants, Medicinal; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sheep; Triterpenes; Ursolic Acid | 1998 |
Antioxidant and antiinflammatory activities of anthocyanins and their aglycon, cyanidin, from tart cherries.
Topics: Animals; Anthocyanins; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Benzopyrans; Cyclooxygenase Inhibitors; Fruit; Male; Sheep | 1999 |
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes.
Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis | 1999 |
Phenolic glycosides from Dirca palustris.
Topics: Animals; Antioxidants; Chromatography, Liquid; Chromatography, Thin Layer; Circular Dichroism; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; In Vitro Techniques; Isoenzymes; Liposomes; Magnetic Resonance Spectroscopy; Male; North America; Phenols; Plants, Medicinal; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sheep; Spectrometry, Mass, Fast Atom Bombardment | 1999 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1.
Topics: Adenine; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Biological Transport; Carrier Proteins; Humans; Kidney; Organophosphonates; Structure-Activity Relationship | 2000 |
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water | 2001 |
Comparative inhibitory effects of different compounds on rat oatpl (slc21a1)- and Oatp2 (Slc21a5)-mediated transport.
Topics: Algorithms; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antitubercular; Antimalarials; Biological Transport, Active; Digoxin; Enzyme Inhibitors; Estradiol; Ibuprofen; LLC-PK1 Cells; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Quinidine; Quinine; Rats; Rifampin; Swine | 2002 |
Indanylidenes. 2. Design and synthesis of (E)-2-(4-chloro-6-fluoro-1-indanylidene)-N-methylacetamide, a potent antiinflammatory and analgesic agent without centrally acting muscle relaxant activity.
Topics: Acetamides; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Hypnotics and Sedatives; Indans; Mice; Muscle Relaxants, Central; Rats; Stereoisomerism; Structure-Activity Relationship | 2003 |
Synthesis and evaluation of S-4-(3-thienyl)phenyl-alpha-methylacetic acid.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Models, Molecular; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Thiophenes | 2004 |
Synthesis and pharmacological evaluation of amide conjugates of NSAIDs with L-cysteine ethyl ester, combining potent antiinflammatory and antioxidant properties with significantly reduced gastrointestinal toxicity.
Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cholesterol; Cysteine; Drug Evaluation; Gastrointestinal Diseases; Lipoproteins, LDL; Mice; Rats; Triglycerides | 2004 |
Novel cyclooxygenase-1 inhibitors discovered using affinity fingerprints.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Combinatorial Chemistry Techniques; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Design; Drug Evaluation, Preclinical; Ibuprofen; Inhibitory Concentration 50; Isoenzymes; Models, Molecular; Models, Theoretical; Molecular Structure; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Quantitative Structure-Activity Relationship | 2004 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Nonsteroidal anti-inflammatory drugs and their analogues as inhibitors of aldo-keto reductase AKR1C3: new lead compounds for the development of anticancer agents.
Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Drug Design; Enzyme Inhibitors; Humans; Hydroxyprostaglandin Dehydrogenases; Molecular Structure; Tumor Cells, Cultured | 2005 |
The geminal dimethyl analogue of Flurbiprofen as a novel Abeta42 inhibitor and potential Alzheimer's disease modifying agent.
Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cyclooxygenase Inhibitors; Disease Models, Animal; Flurbiprofen; Mice; Peptide Fragments | 2006 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Towards the first inhibitors of trihydroxynaphthalene reductase from Curvularia lunata: synthesis of artificial substrate, homology modelling and initial screening.
Topics: Amino Acid Sequence; Ascomycota; Benzopyrans; Enzyme Inhibitors; Fungal Proteins; Melanins; Models, Molecular; Molecular Sequence Data; Oxidoreductases Acting on CH-CH Group Donors; Recombinant Proteins; Structural Homology, Protein; Substrate Specificity | 2008 |
Chlorzoxazone esters of some non-steroidal anti-inflammatory (NSAI) carboxylic acids as mutual prodrugs: design, synthesis, pharmacological investigations and docking studies.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carboxylic Acids; Catalytic Domain; Chlorzoxazone; Computer Simulation; Cyclooxygenase 2; Drug Design; Drug Stability; Esters; Male; Prodrugs; Rats; Rats, Wistar; Structure-Activity Relationship | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence | 2010 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney | 2011 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
Ethanesulfohydroxamic acid ester prodrugs of nonsteroidal anti-inflammatory drugs (NSAIDs): synthesis, nitric oxide and nitroxyl release, cyclooxygenase inhibition, anti-inflammatory, and ulcerogenicity index studies.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase Inhibitors; Edema; Esters; Gastric Mucosa; Humans; Hydroxamic Acids; Ibuprofen; Indomethacin; Male; Naproxen; Nitric Oxide Donors; Nitrogen Oxides; Prodrugs; Rats; Rats, Sprague-Dawley; Stereoisomerism; Stomach Ulcer; Structure-Activity Relationship | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Prediction of in vivo hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver.
Topics: Animals; Cells, Cultured; Child, Preschool; Chimera; Cytochrome P-450 Enzyme System; Drug Evaluation, Preclinical; Drugs, Investigational; Female; Half-Life; Hepatocytes; Humans; Immunomagnetic Separation; Liver; Male; Metabolic Clearance Rate; Mice; Mice, SCID; Recombinant Proteins; Species Specificity; Urokinase-Type Plasminogen Activator | 2012 |
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Modified acidic nonsteroidal anti-inflammatory drugs as dual inhibitors of mPGES-1 and 5-LOX.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Cell Line; Humans; Indomethacin; Intramolecular Oxidoreductases; Lipoxygenase Inhibitors; Microsomes; Prostaglandin-E Synthases; Pyrazoles; Structure-Activity Relationship; Sulfonamides | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
Hybrid fluorescent conjugates of COX-2 inhibitors: search for a COX-2 isozyme imaging cancer biomarker.
Topics: Acridines; Acridones; Biomarkers, Tumor; Celecoxib; Cell Line, Tumor; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Fluorescent Dyes; Humans; Ibuprofen; Microscopy, Confocal; Protein Binding; Pyrazoles; Rhodamines; Structure-Activity Relationship; Sulfonamides | 2013 |
High analgesic and anti-inflammatory in vivo activities of six new hybrids NSAIAs tetrahydropyran derivatives.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Mice; Molecular Structure; Motor Activity; Pyrans | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Inhibition of FAAH, TRPV1, and COX2 by NSAID-serotonin conjugates.
Topics: Amidohydrolases; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Flurbiprofen; Humans; Serotonin; TRPV Cation Channels | 2014 |
Effect of new hybrids based on 5,16-pregnadiene scaffold linked to an anti-inflammatory drug on the growth of a human astrocytoma cell line (U373).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Humans; Molecular Structure; Pregnadienes; Sulindac; Time Factors | 2015 |
Esters of some non-steroidal anti-inflammatory drugs with cinnamyl alcohol are potent lipoxygenase inhibitors with enhanced anti-inflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cinnamates; Edema; Esters; Glycine max; Hyperlipidemias; Indoleacetic Acids; Lipoxygenase Inhibitors; Polyethylene Glycols; Propanols; Propionates; Rats; Thioctic Acid | 2015 |
Amides of non-steroidal anti-inflammatory drugs with thiomorpholine can yield hypolipidemic agents with improved anti-inflammatory activity.
Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholesterol; Cholesterol, LDL; Edema; Hyperlipidemias; Hypolipidemic Agents; Morpholines; Rats; Triglycerides | 2016 |
Design, Synthesis, and Biological Evaluation of Novel Selenium (Se-NSAID) Molecules as Anticancer Agents.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Organoselenium Compounds; Structure-Activity Relationship | 2016 |
Novel triazolothiadiazines act as potent anticancer agents in liver cancer cells through Akt and ASK-1 proteins.
Topics: Antineoplastic Agents; Apoptosis; beta Catenin; Cell Line, Tumor; Cyclin D1; Cytoskeletal Proteins; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; HCT116 Cells; Hepatocytes; Humans; Inhibitory Concentration 50; MAP Kinase Kinase Kinase 5; MCF-7 Cells; Molecular Docking Simulation; Nuclear Proteins; Oxidative Stress; Protein Structure, Secondary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship; Signal Transduction; Thiadiazines; Triazoles | 2016 |
Non-steroidal Anti-inflammatory Drugs Are Caspase Inhibitors.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Caspase Inhibitors; Caspases; Caspases, Initiator; Cell Line; Cell Survival; High-Throughput Screening Assays; Humans; Ibuprofen; Inhibitory Concentration 50; Ketorolac; Naproxen; Small Molecule Libraries; Substrate Specificity | 2017 |
1-Aryl-1H- and 2-aryl-2H-1,2,3-triazole derivatives blockade P2X7 receptor in vitro and inflammatory response in vivo.
Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Inflammation; Lipopolysaccharides; Mice; Molecular Structure; Pleurisy; Receptors, Purinergic P2X7; Structure-Activity Relationship; Triazoles | 2017 |
Lipid Peroxidation and Cyclooxygenase Enzyme Inhibitory Compounds from Prangos haussknechtii.
Topics: Anti-Inflammatory Agents; Antioxidants; Coumarins; Cyclooxygenase Inhibitors; Lipid Peroxidation; Molecular Structure; Plant Extracts; Tetrazoles; Tetrazolium Salts; Thiazoles | 2017 |
Synthesis and biological properties of aryl methyl sulfones.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Carrageenan; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Edema; Humans; Male; Mice; Models, Molecular; Molecular Structure; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Structure-Activity Relationship; Sulfones; Thermodynamics | 2018 |
Mechanisms of Specific versus Nonspecific Interactions of Aggregation-Prone Inhibitors and Attenuators.
Topics: Binding Sites; Buffers; Dose-Response Relationship, Drug; Drug Discovery; False Positive Reactions; Humans; Light; Magnetic Resonance Spectroscopy; Octoxynol; Protein Kinase Inhibitors; Scattering, Radiation; Serum Albumin, Human; Spectrometry, Mass, Electrospray Ionization; Surface Plasmon Resonance; Thermodynamics | 2019 |
Synergistic effect of tolfenamic acid and glycyrrhizic acid on TPA-induced skin inflammation in mice.
Topics: | 2019 |
Synthesis and anticancer activity of open-resorcinarene conjugates.
Topics: Animals; Antineoplastic Agents; Calixarenes; Cell Line, Tumor; Cell Proliferation; Chlorocebus aethiops; COS Cells; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Phenylalanine; Structure-Activity Relationship | 2020 |
The Structural Basis for Nonsteroidal Anti-Inflammatory Drug Inhibition of Human Dihydrofolate Reductase.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Crystallography, X-Ray; Drug Design; Folic Acid; Folic Acid Antagonists; Humans; Models, Molecular; Tetrahydrofolate Dehydrogenase | 2020 |
Diflunisal Derivatives as Modulators of ACMS Decarboxylase Targeting the Tryptophan-Kynurenine Pathway.
Topics: Bacterial Proteins; Binding Sites; Biosynthetic Pathways; Carboxy-Lyases; Catalytic Domain; Crystallography, X-Ray; Diflunisal; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kynurenine; Molecular Docking Simulation; NAD; Pseudomonas fluorescens; Structure-Activity Relationship; Tryptophan | 2021 |
New organoselenides (NSAIDs-Se derivatives) as potential anticancer agents: Synthesis, biological evaluation and in silico calculations.
Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Structure; Organoselenium Compounds; Structure-Activity Relationship; Tumor Cells, Cultured | 2021 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Acute erosive gastritis induced by aspirin, ketoprofen, ibuprofen, and naproxen: its prevention by metiamide and cimetidine.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Mucosa; Gastritis; Guanidines; Histamine H2 Antagonists; Ibuprofen; Imidazoles; Ketoprofen; Male; Metiamide; Naproxen; Rats; Thiourea | 1977 |
The new anti-inflammatory agents: phenylalkanoic acids.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Fenoprofen; Ibuprofen; Naproxen; Phenylpropionates | 1976 |
The new antirheumatic drugs.
Topics: Anti-Inflammatory Agents; Fenoprofen; Flufenamic Acid; Humans; Ibuprofen; Ketoprofen; Mefenamic Acid; Naproxen; Penicillamine; Phenylacetates; Rheumatic Diseases; Salicylates | 1975 |
New non-steroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Fenoprofen; Humans; Ibuprofen; Naproxen; Penicillamine; Tolmetin | 1977 |
New nonsteroidal anti-inflammatory drugs. Prospective survey of relative merits.
Topics: Anti-Inflammatory Agents; Fenoprofen; Humans; Ibuprofen; Naproxen; Rheumatic Diseases; Tolmetin | 1977 |
Old and new pharmaceutical non-steroidal compounds prescribed for the management of patients with rheumatic diseases.
Topics: Anti-Inflammatory Agents; Fenoprofen; Humans; Ibuprofen; Ketoprofen; Naproxen; Rheumatic Diseases; Sulindac; Tolmetin | 1979 |
Inhibition of human leucocytes locomotion by anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Cell Movement; Chemotaxis, Leukocyte; Depression, Chemical; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Neutrophils; Salicylates | 1979 |
Drugs for dysmenorrhea.
Topics: Acetaminophen; Aspirin; Dysmenorrhea; Female; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Nalbuphine; Naproxen; Time Factors | 1979 |
Comparisons of tolerability findings in international clinical trials.
Topics: Arthritis, Rheumatoid; Aspirin; Cardiovascular System; Clinical Trials as Topic; Diclofenac; Drug Tolerance; Follow-Up Studies; Gastrointestinal Diseases; Hematologic Tests; Humans; Ibuprofen; Indomethacin; International Cooperation; Naproxen; Phenylacetates; Time Factors | 1979 |
Nonsteroidal antiinflammatory drugs: new alternatives for rheumatic disease.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Drug Therapy, Combination; Fenoprofen; Humans; Ibuprofen; Naproxen; Phenylpropionates; Pyrroles; Tolmetin | 1978 |
Effect of three nonsteroidal anti-inflammatory agents on platelet function and prostaglandin synthesis in vitro.
Topics: Adenosine Diphosphate; Adult; Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Epinephrine; Female; Humans; Ibuprofen; In Vitro Techniques; Male; Naproxen; Platelet Aggregation; Prostaglandin Antagonists; Prostaglandins | 1978 |
Reduction of renal function by newer nonsteroidal anti-inflammatory drugs.
Topics: Adult; Anti-Inflammatory Agents; Depression, Chemical; Female; Fenoprofen; Humans; Ibuprofen; Kidney; Kidney Function Tests; Lupus Erythematosus, Systemic; Middle Aged; Naproxen; Prostaglandins E | 1978 |
Nonsteroidal anti-inflammatory drug treatment for arthritis.
Topics: Anti-Inflammatory Agents; Arthritis; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Naproxen; Oxyphenbutazone; Phenylbutazone; Salicylates | 1978 |
The identification of ibuprofen and analogues in urine by pyrolysis gas chromatography mass spectrometry.
Topics: Anti-Inflammatory Agents; Chromatography, Gas; Fenoprofen; Humans; Ibuprofen; Ketoprofen; Mass Spectrometry; Naproxen; Propionates | 1978 |
Prostaglandin synthetase activity from human rheumatoid synovial microsomes. Effect of 'aspirin-like' drug therapy.
Topics: Adult; Aged; Arachidonic Acids; Arthritis, Rheumatoid; Aspirin; Cyclooxygenase Inhibitors; Female; Humans; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Microsomes; Middle Aged; Mixed Function Oxygenases; Naproxen; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Prostaglandins F; Synovial Membrane | 1976 |
Aspirin and newer anti-inflammatory agents in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Fenoprofen; Humans; Ibuprofen; Indomethacin; Naproxen; Peptic Ulcer; Phenylbutazone; Tolmetin | 1977 |
Some effects of non-steroidal anti-inflammatory drugs on leucocyte migration.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Cell Movement; Edema; Fenoprofen; Ibuprofen; Indomethacin; Ketoprofen; Leukocytes; Male; Methotrexate; Naproxen; Phenylbutazone; Pleurisy; Rats | 1976 |
New nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Fenoprofen; Humans; Ibuprofen; Naphthaleneacetic Acids; Naproxen; Phenylpropionates; Pyrroles; Tolmetin | 1976 |
Medical management of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Aspirin; Chloroquine; Gold; Humans; Ibuprofen; Indomethacin; Naproxen; Occupational Therapy; Phenylbutazone; Physical Therapy Modalities | 1976 |
More on the new arthritis drugs.
Topics: Arthritis; Fenoprofen; Humans; Ibuprofen; Naproxen; Tolmetin | 1976 |
Relationship between the inhibitory activity on 'RCS' and prostaglandins synthesis and the anti-inflammatory activity of ketoprofen and several other non-steroidal anti-inflammatory agents.
Topics: Abscess; Animals; Anti-Inflammatory Agents; Aorta; Arachidonic Acids; Aspirin; Benzophenones; Colon; Guinea Pigs; Hydroxy Acids; Ibuprofen; In Vitro Techniques; Indomethacin; Ketoprofen; Lung; Muscle Contraction; Naproxen; Phenylbutazone; Prostaglandin Antagonists; Prostaglandins; Pyrans | 1976 |
[Ibuprofen (Brufen) and naproxen (Naprosyn)].
Topics: Humans; Ibuprofen; Naphthaleneacetic Acids; Naproxen; Phenylpropionates; Rheumatic Diseases | 1976 |
[Effects of drugs on cell culture (I)].
Topics: Animals; Cell Division; Drug Evaluation, Preclinical; Ibuprofen; In Vitro Techniques; L Cells; Mice; Naproxen; Phenylacetates; Propylene Glycols; Xanthenes | 1975 |
[Effects of drugs on cell culture (II)].
Topics: Aminopyrine; Cell Division; Cell Line; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Embryo, Mammalian; Fibroblasts; Humans; Ibuprofen; Muscles; Naproxen; Phenylacetates; Skin; Xanthenes | 1975 |
[Effects of drugs on cultured cells (III)].
Topics: Aminopyrine; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ibuprofen; Mitosis; Naproxen; Phenylacetates; Xanthenes | 1975 |
Pharmacological agents used in implant dentistry.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Dental Implantation, Endosseous; Diflunisal; Humans; Ibuprofen; Naproxen; Pain; Steroids | 1992 |
High-performance liquid chromatographic determination of naproxen, ibuprofen and diclofenac in plasma and synovial fluid in man.
Topics: Chromatography, High Pressure Liquid; Diclofenac; Humans; Ibuprofen; Naproxen; Reproducibility of Results; Spectrophotometry, Ultraviolet; Synovial Fluid | 1992 |
Dissociation between prostaglandin levels and blood flow to the retina and choroid in the newborn pig after nonsteroidal antiinflammatory drugs.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Choroid; Ibuprofen; Indomethacin; Naproxen; Osmolar Concentration; Prostaglandins; Regional Blood Flow; Retina; Retinal Vessels; Swine | 1992 |
Effects of NSAIDs on NNK-induced pulmonary and gastric tumorigenesis in A/J mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Carcinogens; Drug Interactions; Female; Ibuprofen; Lung Neoplasms; Mice; Mice, Inbred A; Naproxen; Nitrosamines; Piroxicam; Stomach Neoplasms; Sulindac; Time Factors | 1992 |
Ester and amide prodrugs of ibuprofen and naproxen: synthesis, anti-inflammatory activity, and gastrointestinal toxicity.
Topics: Amides; Animals; Digestive System; Esters; Ibuprofen; Male; Mice; Mice, Inbred Strains; Naproxen; Prodrugs; Rats; Rats, Inbred Strains | 1992 |
Inhibition kinetics of hepatic microsomal long chain fatty acid-CoA ligase by 2-arylpropionic acid non-steroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Coenzyme A Ligases; Fenoprofen; Ibuprofen; Ketoprofen; Kinetics; Male; Microsomes, Liver; Naproxen; Palmitoyl Coenzyme A; Rats; Rats, Inbred Strains; Repressor Proteins; Saccharomyces cerevisiae Proteins; Stereoisomerism; Substrate Specificity; Triglycerides | 1992 |
Effects of NSAIDs on beagle crevicular cyclooxygenase metabolites and periodontal bone loss.
Topics: Administration, Oral; Administration, Topical; Alveolar Bone Loss; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Dinoprostone; Dogs; Flurbiprofen; Gingival Crevicular Fluid; Ibuprofen; Naproxen; Prostaglandins F; Thromboxane B2 | 1992 |
The effects of a salicylate, ibuprofen, and naproxen on the disposition of methotrexate in patients with rheumatoid arthritis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Blood Proteins; Choline; Female; Humans; Ibuprofen; Kidney; Male; Metabolic Clearance Rate; Methotrexate; Middle Aged; Naproxen; Protein Binding; Salicylates | 1992 |
[Pseudoporphyria].
Topics: Adult; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Porphyrias; Quinidine; Skin Diseases; Ultraviolet Rays | 1992 |
Tenidap, in contrast to several available nonsteroidal antiinflammatory drugs, potently inhibits the release of activated neutrophil collagenase.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Hypochlorous Acid; Ibuprofen; In Vitro Techniques; Indoles; Indomethacin; Microbial Collagenase; Naproxen; Neutrophils; Oxindoles; Peroxidase; Piroxicam; Reference Values; Superoxides | 1991 |
Differences in the effects in the newborn piglet of various nonsteroidal antiinflammatory drugs on cerebral blood flow but not on cerebrovascular prostaglandins.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cerebrovascular Circulation; Ibuprofen; Indomethacin; Naproxen; Prostaglandins; Swine | 1991 |
Management of IUD-associated menorrhagia in female rhesus monkeys (Macaca mulatta).
Topics: Aminocaproic Acid; Animals; Anti-Inflammatory Agents; Antifibrinolytic Agents; Endometrium; Female; Ibuprofen; Indomethacin; Intrauterine Devices; Iron; Macaca mulatta; Menorrhagia; Menstrual Cycle; Menstruation; Naproxen; Plant Extracts; Tissue Plasminogen Activator; Tranexamic Acid | 1991 |
Improved in vitro antigen-specific antibody synthesis in two patients with common variable immunodeficiency taking an oral cyclooxygenase and lipoxygenase inhibitor (ketoprofen).
Topics: Administration, Oral; Adolescent; Adult; Antibody Formation; B-Lymphocytes; Cell Differentiation; Child; Cyclooxygenase Inhibitors; Female; Humans; Ibuprofen; Immunologic Deficiency Syndromes; Ketoprofen; Lipoxygenase Inhibitors; Lymphocyte Activation; Male; Middle Aged; Mitogens; Naproxen | 1991 |
A prospective nationwide cross-sectional study of NSAID usage in 1331 patients with ankylosing spondylitis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cross-Sectional Studies; Diclofenac; Female; Gold; Humans; Ibuprofen; Male; Methotrexate; Middle Aged; Naproxen; Penicillamine; Piroxicam; Prednisolone; Prospective Studies; Spondylitis, Ankylosing; Sulfasalazine; United Kingdom | 1990 |
Photoprotective effect of topical anti-inflammatory agents against ultraviolet radiation-induced chronic skin damage in the hairless mouse.
Topics: Administration, Cutaneous; Administration, Topical; Animals; Anti-Inflammatory Agents; Chronic Disease; Female; Hydrocortisone; Ibuprofen; Mice; Mice, Hairless; Naproxen; Photosensitivity Disorders; Skin; Skin Aging; Ultraviolet Rays | 1990 |
A method to predict the percutaneous permeability of various compounds: shed snake skin as a model membrane.
Topics: Animals; Cell Membrane Permeability; Hydrocortisone; Ibuprofen; Indomethacin; Ketoprofen; Models, Biological; Molecular Weight; Naproxen; Particle Size; Progesterone; Skin; Snakes | 1990 |
Inhibition of human periodontal prostaglandin E2 synthesis with selected agents.
Topics: Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dinoprostone; Eicosapentaenoic Acid; Flurbiprofen; Humans; Ibuprofen; Ketoprofen; Meclofenamic Acid; Naproxen; Periodontitis; Periodontium; Vitamin E | 1990 |
Resolution of derivatized acids and amines on JTB-X: a new urea bonded chiral stationary phase.
Topics: Acids; Amines; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry; Fenoprofen; Ibuprofen; Naproxen; Spectrophotometry, Infrared; Stereoisomerism; Urea | 1990 |
Effects of calcium on the vasopressin-sensitive cAMP metabolism in medullary tubules.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Animals; Arginine Vasopressin; Calcimycin; Calcium; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Ibuprofen; Kidney Tubules; Kidney Tubules, Collecting; Male; Naproxen; Rats; Rats, Inbred Strains; Rotenone; Vasopressins | 1985 |
Role of plasminogen activators and leukocytes in IUD-induced inflammation: effect of some anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Endometritis; Epithelium; Female; Ibuprofen; Indomethacin; Intrauterine Devices; Leukocyte Count; Naproxen; Neutrophils; Organ Size; ortho-Aminobenzoates; Plasminogen Activators; Rats; Uterus | 1989 |
Metabolic chiral inversion of anti-inflammatory 2-arylpropionates: lack of reaction in liver homogenates, and study of methine proton acidity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Flurbiprofen; Guinea Pigs; Ibuprofen; Isomerism; Kinetics; Liver; Male; Naproxen; Protons; Rats; Rats, Inbred Strains; Suprofen | 1988 |
Effects of isoxicam and other non-steroidal anti-inflammatory drugs on arachidonic acid metabolism by rat peritoneal leucocytes.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Calcimycin; Hydroxyeicosatetraenoic Acids; Ibuprofen; In Vitro Techniques; Indomethacin; Leukocytes; Male; Naproxen; Piroxicam; Prostaglandins; Rats; Rats, Inbred Strains; Thiazines | 1985 |
Non-steroidal anti-inflammatory drugs and bleeding peptic ulcer.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Duodenal Ulcer; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Osteoarthritis; Peptic Ulcer Hemorrhage; Piroxicam; Smoking; Stomach Ulcer; Surveys and Questionnaires; Thiazines | 1986 |
Analgesic and anti-inflammatory activities in rats of alpha-(3,5-di-t-butyl-4-hydroxybenzylidene)-gamma-butyrolactone (KME-4), and its intestinal damage.
Topics: 4-Butyrolactone; Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Capillary Permeability; Edema; Furans; Ibuprofen; Indomethacin; Intestinal Diseases; Lethal Dose 50; Male; Naproxen; Rats; Rats, Inbred Strains | 1986 |
[Drug therapy of dysmenorrhea].
Topics: Adrenergic beta-Agonists; Adult; Aspirin; Calcium Channel Blockers; Contraceptives, Oral; Dysmenorrhea; Female; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Magnesium; Mefenamic Acid; Models, Biological; Naproxen; Progestins | 1988 |
Acute renal failure associated with acute pyelonephritis and consumption of non-steroidal anti-inflammatory drugs.
Topics: Acute Kidney Injury; Adult; Aged; Anti-Inflammatory Agents; Apazone; Female; Humans; Ibuprofen; Ketoprofen; Middle Aged; Naproxen; Pyelonephritis | 1986 |
Effect of diclofenac sodium on the arachidonic acid cascade.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Leukocytes; Lipoxygenase Inhibitors; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Naproxen; Phospholipids; Piroxicam; Prostaglandins E; Rats; SRS-A; Thiazines; Triglycerides | 1986 |
The history of diclofenac.
Topics: Chemical Phenomena; Chemistry; Diclofenac; Humans; Hydrogen-Ion Concentration; Ibuprofen; Indenes; Indomethacin; Ketoprofen; Naproxen; Phenylbutazone; Piroxicam; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship; Thiazines | 1986 |
Arachidonic acid-induced inflammation: inhibition by dual inhibitor of arachidonic acid metabolism, SK&F 86002.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Ibuprofen; Imidazoles; Inflammation; Male; Masoprocol; Mice; Mice, Inbred BALB C; Naproxen; Peritonitis; Piroxicam; Pyrazoles; Thiazoles | 1987 |
Cell damage unmasks 15-lipoxygenase activity in human neutrophils.
Topics: Acetates; Arachidonate Lipoxygenases; Aspirin; Dose-Response Relationship, Drug; Etodolac; Fluorometry; Flurbiprofen; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; L-Lactate Dehydrogenase; Lipoxygenase; Naproxen; Neutrophils; Phenylbutazone | 1985 |
Inhibition by anti-inflammatory agents of contraction induced by epidermal growth factor-urogastrone in isolated longitudinal smooth muscle strips from guinea-pig stomach.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Auranofin; Cycloheximide; Dexamethasone; Epidermal Growth Factor; Guinea Pigs; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Naproxen; Steroids; Stomach | 1988 |
Piroxicam and gastrointestinal bleeding.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Drug Utilization; Female; Gastrointestinal Hemorrhage; Hospitalization; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Norway; Piroxicam; Prospective Studies | 1986 |
Reversible acute decrease in renal function by NSAIDs in cirrhosis.
Topics: Acute Disease; Creatinine; Female; Humans; Ibuprofen; Indenes; Kidney; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Naproxen; Prostaglandins; Sulindac; Urodynamics | 1987 |
A study of naproxen sodium and ibuprofen in primary dysmenorrhoea.
Topics: Adolescent; Adult; Dysmenorrhea; Female; Humans; Ibuprofen; Naproxen; Random Allocation | 1987 |
[Granulated ibuprofen in rheumatoid arthritis. Comparison of its efficacy and tolerability with naproxen].
Topics: Adult; Aged; Arthritis, Rheumatoid; Dosage Forms; Drug Evaluation; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Random Allocation | 1986 |
Colitis caused by non-steroidal anti-inflammatory drugs.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Female; Flufenamic Acid; Humans; Ibuprofen; Mefenamic Acid; Naproxen; Proctocolitis | 1986 |
NSAID-plasma concentration monitoring--optimizing treatment of R.A.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Humans; Ibuprofen; Indomethacin; Kinetics; Metabolic Clearance Rate; Naproxen; Phenylacetates; Phenylbutazone | 1985 |
The history of diclofenac.
Topics: Diclofenac; History, 20th Century; Ibuprofen; Ketoprofen; Models, Molecular; Naproxen; Phenylbutazone; Piroxicam; Solubility; Structure-Activity Relationship; Thiazines | 1985 |
Plasma volume and protein content in progressive exercise: influence of cyclooxygenase inhibitors.
Topics: Adult; Blood Proteins; Capillary Permeability; Cyclooxygenase Inhibitors; Hematocrit; Hemoglobins; Humans; Ibuprofen; Male; Naproxen; Physical Exertion; Plasma Volume; Time Factors | 1985 |
The effects of diclofenac sodium on arachidonic acid metabolism.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Chemotaxis, Leukocyte; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indomethacin; Leukocytes; Lipoxygenase; Naproxen; Phospholipases A; Phospholipases A2; Phospholipids; Piroxicam; Prostaglandins E; SRS-A; Thiazines; Triglycerides | 1985 |
Effects of diclofenac sodium on arachidonic acid metabolism.
Topics: Arachidonic Acid; Arachidonic Acids; Diclofenac; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Leukocytes; Monocytes; Naproxen; Neutrophils; Piroxicam; SRS-A; Thiazines | 1985 |
Comparative effects of four prostaglandin synthesis inhibitors on the obstructed kidney in the dog.
Topics: Animals; Blood Pressure; Dogs; Female; Ibuprofen; Indomethacin; Ketorolac; Kidney Pelvis; Naproxen; Pressure; Prostaglandin Antagonists; Tolmetin; Ureteral Obstruction | 1986 |
European experience with flurbiprofen. A new analgesic/anti-inflammatory agent.
Topics: Aspirin; Drug Evaluation; Europe; Flurbiprofen; Humans; Ibuprofen; Indomethacin; Naproxen; Propionates | 1986 |
Arachidonic acid metabolites stimulate phosphatidylcholine secretion in primary cultures of type II pneumocytes.
Topics: Animals; Arachidonic Acids; Catechols; Cells, Cultured; Dose-Response Relationship, Drug; Flufenamic Acid; Ibuprofen; In Vitro Techniques; Indomethacin; Lung; Male; Masoprocol; Naproxen; Phosphatidylcholines; Rats; Rats, Inbred Strains | 1985 |
Nephrotoxicity from nonsteroidal anti-inflammatory drugs.
Topics: Acute Disease; Acute Kidney Injury; Aged; Anti-Inflammatory Agents; Aspirin; Female; Humans; Hyperkalemia; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Nephritis, Interstitial | 1985 |
[Non-steroidal anti-inflammatory agents in juvenile rheumatoid arthritis].
Topics: Anti-Inflammatory Agents; Arthritis, Juvenile; Aspirin; Child; Humans; Ibuprofen; Naproxen | 1985 |
Nonsteroidal anti-inflammatory agents. A review of the literature.
Topics: Absorption; Anti-Inflammatory Agents; Aspirin; Diflunisal; Drug Interactions; Female; Fenoprofen; Half-Life; Humans; Ibuprofen; Indomethacin; Kinetics; Meclofenamic Acid; Naproxen; Phenylbutazone; Piroxicam; Pregnancy; Thiazines; Tolmetin | 1985 |
Diclofenac sodium in the treatment of rheumatoid arthritis and osteoarthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Diclofenac; Double-Blind Method; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Osteoarthritis; Pain | 1985 |
Diclofenac in the treatment of painful joints and traumatic tendinitis (including strains and sprains): a brief review.
Topics: Diclofenac; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Joint Diseases; Ketoprofen; Naproxen; Pain; Sprains and Strains; Tendinopathy | 1985 |
Naproxen sodium, ibuprofen and a placebo in dysmenorrhea.
Topics: Activities of Daily Living; Adult; Double-Blind Method; Dysmenorrhea; Female; Humans; Ibuprofen; Naproxen; Palliative Care; Placebos | 1982 |
Comparative effects of long term treatment with etodolac, naproxen and ibuprofen on articular and bone changes associated with adjuvant arthritis in rats.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Body Weight; Bone and Bones; Cartilage, Articular; Etodolac; Ibuprofen; Naproxen; Radiography; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Comparison of the effects of sulindac with other cyclooxygenase inhibitors on prostaglandin excretion and renal function in normal and chronic bile duct-ligated dogs and swine.
Topics: Animals; Bile Ducts; Cyclooxygenase Inhibitors; Dogs; Female; Glomerular Filtration Rate; Ibuprofen; Indenes; Kidney; Ligation; Liver Diseases; Naproxen; Prostaglandins; Sulindac; Swine; Swine, Miniature | 1984 |
Drug prescription patterns for rheumatic disorders in Sweden.
Topics: Administration, Oral; Anti-Inflammatory Agents; Chloroquine; Drug Prescriptions; Drug Utilization; Gold Sodium Thiomalate; Hospitals, University; Humans; Ibuprofen; Indomethacin; Naproxen; Penicillamine; Pharmacy Service, Hospital; Phenylbutazone; Rheumatic Diseases; Rheumatology; Suppositories; Sweden | 1984 |
A clinical evaluation of the antiarthritic agents.
Topics: Anti-Inflammatory Agents; Antimalarials; Arthritis; Aspirin; Diflunisal; Fenoprofen; Glucocorticoids; Gold; Humans; Ibuprofen; Immunosuppressive Agents; Indomethacin; Naproxen; ortho-Aminobenzoates; Penicillamine; Piroxicam; Prostaglandin Antagonists; Salicylates; Sulindac; Thiazines; Tolmetin | 1984 |
Effect on platelet aggregation of oral administration of 10 non-steroidal analgesics to humans.
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Diclofenac; Diflunisal; Epinephrine; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Oxyphenbutazone; Piroxicam; Platelet Aggregation; Thiazines; Time Factors | 1984 |
Effect of ibuprofen and naproxen on implantation and pregnancy in rat.
Topics: Animals; Embryo Implantation; Female; Ibuprofen; Male; Naproxen; Pregnancy; Pregnancy, Animal; Rats | 1984 |
Peripherally acting analgesics.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Aspirin; Diflunisal; Fenoprofen; Humans; Ibuprofen; Mefenamic Acid; Naproxen; Pain; Primary Health Care | 1984 |
Poisoning after overdose with non-steroidal anti-inflammatory drugs.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Child, Preschool; Diflunisal; Female; Fenoprofen; Feprazone; Humans; Ibuprofen; Indomethacin; Ketoprofen; London; Male; Mefenamic Acid; Naproxen; Oxyphenbutazone; Phenylbutazone; Piroxicam; Thiazines; Tolmetin | 1984 |
[Comparative efficacy of brufen, naproxen and acetylsalicylic acid in the treatment of torpid rheumatism].
Topics: Anti-Inflammatory Agents; Aspirin; Humans; Ibuprofen; Naproxen; Rheumatic Diseases | 1983 |
Hematuria and the use of nonsteroidal anti-inflammatory drugs.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Female; Hematuria; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen | 1984 |
Comparative gastric ulcerogenic effects of meseclazone, 5-chlorosalicylic acid and other nonsteroidal anti-inflammatory drugs following acute and repeated oral administration to rats.
Topics: Animals; Anti-Inflammatory Agents; Benzoxazines; Biotransformation; Fenoprofen; Ibuprofen; Indomethacin; Male; Naproxen; Oxazines; Peptic Ulcer Hemorrhage; Phenylbutazone; Rats; Salicylates; Stomach Ulcer; Time Factors; Tolmetin | 1980 |
Dysmenorrhoea: effective new approaches to a controversial problem.
Topics: Cyclooxygenase Inhibitors; Dysmenorrhea; Female; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Naproxen | 1980 |
Antagonistic effect of non-steroidal anti-inflammatory drugs on frusemide-induced diuresis in cardiac failure.
Topics: Aged; Diuresis; Female; Furosemide; Heart Failure; Humans; Ibuprofen; Male; Naproxen | 1981 |
Effect of nonsteroidal antiinflammatory drugs on human monocyte chemotaxis in vitro.
Topics: Anti-Inflammatory Agents; Cell Survival; Chemotaxis, Leukocyte; Humans; Ibuprofen; Indomethacin; Monocytes; Naproxen | 1983 |
Renal papillary necrosis following regular consumption of non-steroidal anti-inflammatory drugs.
Topics: Aged; Anti-Inflammatory Agents; Humans; Ibuprofen; Indomethacin; Ketoprofen; Kidney Papillary Necrosis; Male; Middle Aged; Naproxen; Osteoarthritis | 1982 |
Oral antipyretic therapy evaluation of the propionic acid derivatives ibuprofen, ketoprofen, fenoprofen and naproxen.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Fenoprofen; Fever; Ibuprofen; Ketoprofen; Naproxen | 1980 |
Dysmenorrhea: a new approach to an old problem.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Dysmenorrhea; Female; Humans; Ibuprofen; Mefenamic Acid; Naproxen | 1981 |
Rheumatoid arthritis IV: non-steroidal anti-inflammatory agents use in treatment.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Fenoprofen; Humans; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone; Tolmetin | 1982 |
Osteoarthritis and non-steroidal and anti-inflammatory drugs: a multi-centre comparative study.
Topics: Aged; Diclofenac; Female; Hip Joint; Humans; Ibuprofen; Indenes; Knee Joint; Male; Naproxen; Osteoarthritis; Sulindac | 1982 |
Cognitive dysfunction associated with naproxen and ibuprofen in the elderly.
Topics: Aged; Arthritis, Rheumatoid; Cognition Disorders; Female; Humans; Ibuprofen; Joint Diseases; Male; Naproxen | 1982 |
Current review and comparison of the new nonsteroidal anti-inflammatory agents.
Topics: Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Drug Administration Schedule; Fenoprofen; Humans; Ibuprofen; Naproxen; Prostaglandins; Sulindac; Tolmetin | 1980 |
Effective of acetylsalicylic acid, indomethacin, phenylbutazone, paracetamol, ibuprofen and naproxen on canine gastric mucosa: a histological and ultrastructural study.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Aspirin; Dogs; Gastric Mucosa; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone | 1981 |
The effects of four platelet inhibitors on human platelets using two adhesiveness test systems.
Topics: Adult; Aspirin; Collagen; Female; Glass; Humans; Ibuprofen; In Vitro Techniques; Male; Naproxen; Phosphodiesterase Inhibitors; Platelet Adhesiveness; Pyrimidines | 1980 |
Nonsteroidal antiinflammatory drugs: effects on normal and interleukin 1 treated human articular chondrocyte metabolism in vitro.
Topics: Cartilage, Articular; Cell Division; Cells, Cultured; Collagenases; Diclofenac; Dinoprostone; Extracellular Matrix; Humans; Ibuprofen; Interleukin-1; Interleukin-6; Naproxen; Reference Values; Salicylates | 1995 |
Alterations in the electroretinogram of newborn piglets by propionic acid-derivative nonsteroidal antiinflammatory drugs but not by indomethacin and diclofenac.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Electroretinography; Flurbiprofen; Ibuprofen; Indomethacin; Naproxen; Photoreceptor Cells; Propionates; Prostaglandins; Retina; Swine | 1995 |
Pharmacokinetic analysis of diethylcarbonate prodrugs of ibuprofen and naproxen.
Topics: Animals; Diethyl Pyrocarbonate; Dogs; Drug Stability; Ibuprofen; Naproxen; Prodrugs | 1995 |
Effects of nonsteroidal antiinflammatory drugs on oxidative pathways in A/J mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Deoxyguanosine; Dinoprostone; DNA; DNA Damage; Female; Ibuprofen; Lipid Peroxidation; Liver; Lung; Lung Neoplasms; Mice; Mice, Inbred A; Naproxen; Nitrosamines; Oxidation-Reduction; Oxidative Stress; Piroxicam; Sulindac | 1995 |
Surgically induced diffuse scleritis following cataract surgery.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anesthesia, General; Cataract Extraction; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Scleritis | 1994 |
Determination of drugs by direct injection of plasma into a biocompatible extraction column based on a protein-entrapped hydrophobic phase.
Topics: Biocompatible Materials; Blood Proteins; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Ibuprofen; Naproxen; Pharmaceutical Preparations; Phenytoin; Propranolol; Reproducibility of Results | 1994 |
A method for the determination of UDP-glucuronosyltransferase activity toward arylcarboxylic acids.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbon Radioisotopes; Carboxylic Acids; Chromatography, Liquid; Clofibric Acid; Enzyme Activation; Glucuronates; Glucuronosyltransferase; Ibuprofen; Kinetics; Male; Methods; Naproxen; Phenylpropionates; Rats; Rats, Wistar; Reproducibility of Results; Uridine Diphosphate Glucuronic Acid | 1993 |
Assessing physician choice of nonsteroidal antiinflammatory drugs in a health maintenance organization.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Drug Utilization Review; Health Maintenance Organizations; Humans; Ibuprofen; Michigan; Middle Aged; Naproxen; Practice Patterns, Physicians'; Retrospective Studies | 1993 |
Reinduction of the hypnotic effects of thiopental with NSAIDs by decreasing thiopental plasma protein binding in humans.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Proteins; Female; Humans; Hypnotics and Sedatives; Ibuprofen; In Vitro Techniques; Longitudinal Studies; Middle Aged; Naproxen; Protein Binding; Salicylates; Salicylic Acid; Sleep; Temperature; Thiopental | 1993 |
Do non-steroidal anti-inflammatory drugs have an effect on gastric cell turnover?
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Bromodeoxyuridine; Cell Division; Diclofenac; Gastric Mucosa; Gastroscopy; Humans; Ibuprofen; Immunohistochemistry; Indomethacin; Mefenamic Acid; Naproxen; Pyloric Antrum | 1995 |
Novel separation scheme for capillary electrophoresis of enantiomers.
Topics: Aspartic Acid; Buffers; Cyclodextrins; Dansyl Compounds; Electrophoresis, Capillary; Glutamic Acid; Hydrogen-Ion Concentration; Ibuprofen; Metaproterenol; Methamphetamine; Naproxen; Pharmaceutical Preparations; Stereoisomerism | 1995 |
In vitro plasma protein binding of zileuton and its N-dehydroxylated metabolite.
Topics: Adult; Anti-Allergic Agents; Anti-Inflammatory Agents; Anticoagulants; Blood Proteins; Chromatography, High Pressure Liquid; Drug Interactions; Female; Hematocrit; Humans; Hydroxylation; Hydroxyurea; Ibuprofen; In Vitro Techniques; Isotope Labeling; Lipoxygenase Inhibitors; Male; Naproxen; Prednisolone; Protein Binding; Salicylates; Stereoisomerism; Terfenadine; Theophylline; Warfarin | 1995 |
Enhancement by cyclo-oxygenase inhibitors of platelet-activating factor production in thapsigargin-stimulated macrophages.
Topics: Animals; Arachidonic Acid; Bucladesine; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Ibuprofen; Indomethacin; Macrophages, Peritoneal; Male; Naproxen; Platelet Activating Factor; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Terpenes; Thapsigargin | 1995 |
The effect of octanoic acid on the binding of the enantiomers of ibuprofen and naproxen to human serum albumin: a chromatographic implication.
Topics: Calorimetry; Caprylates; Chromatography; Ibuprofen; Naproxen; Protein Binding; Serum Albumin; Stereoisomerism; Thermodynamics | 1996 |
Displacement of valproic acid and carbamazepine from protein binding in normal and uremic sera by tolmetin, ibuprofen, and naproxen: presence of inhibitor in uremic serum that blocks valproic acid-naproxen interactions.
Topics: Binding, Competitive; Blood Proteins; Carbamazepine; Cyclooxygenase Inhibitors; Drug Interactions; Humans; Ibuprofen; Naproxen; Protein Binding; Reference Values; Tolmetin; Uremia; Valproic Acid | 1996 |
In vitro displacement of phenytoin from protein binding by nonsteroidal antiinflammatory drugs tolmetin, ibuprofen, and naproxen in normal and uremic sera.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Humans; Ibuprofen; Naproxen; Phenytoin; Protein Binding; Serum Albumin; Tolmetin; Uremia | 1996 |
Phototoxicity of non-steroidal anti-inflammatory drugs: in vitro studies with visible light.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dermatitis, Phototoxic; Diclofenac; Erythrocytes; Hemolysis; Humans; Ibuprofen; In Vitro Techniques; Ketoprofen; Light; Naproxen; Phenylbutazone; Photosensitizing Agents; Piroxicam; Propionates | 1996 |
Assessment of the antiexudative and antiproliferative activities of non-steroidal anti-inflammatory drugs in inflammatory models developed in rats by subcutaneous implantation of bacterial cell walls from the dental plaque.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Cell Division; Cell Wall; Child; Dental Plaque; DNA Replication; Duodenum; Edema; Exudates and Transudates; Granuloma; Growth Inhibitors; Humans; Ibuprofen; Indomethacin; Inflammation; Intestinal Mucosa; Naproxen; Rats; Sulindac | 1996 |
Effects of the combined oral administration of NSAIDs and dextromethorphan on behavioral symptoms indicative of arthritic pain in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Behavior, Animal; Dextromethorphan; Diclofenac; Drug Interactions; Drug Therapy, Combination; Etodolac; Ibuprofen; Injections, Intraperitoneal; Male; Naproxen; Pain; Piroxicam; Rats; Rats, Sprague-Dawley | 1996 |
A quantitative circular dichroic investigation of the binding of the enantiomers of ibuprofen and naproxen to human serum albumin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Naproxen; Protein Binding; Serum Albumin; Stereoisomerism | 1997 |
Benzydamine inhibits the release of tumor necrosis factor-alpha and monocyte chemotactic protein-1 by Candida albicans-stimulated human peripheral blood cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzydamine; Candidiasis; Chemokine CCL2; Female; Humans; Ibuprofen; Lymphocytes; Naproxen; Tumor Necrosis Factor-alpha; Vaginitis | 1997 |
Comparative mutagenic and genotoxic effects of three propionic acid derivatives ibuprofen, ketoprofen and naproxen.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Marrow Cells; Ibuprofen; In Vitro Techniques; Ketoprofen; Male; Mice; Microsomes, Liver; Mutagenicity Tests; Mutagens; Naproxen; Rats; Salmonella typhimurium; Sister Chromatid Exchange | 1997 |
Measurement of plasma ibuprofen by gas chromatography-mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Cystic Fibrosis; Drug Monitoring; Fenoprofen; Gas Chromatography-Mass Spectrometry; Humans; Ibuprofen; Ketoprofen; Naproxen; Sensitivity and Specificity | 1997 |
Development of an HPLC assay to study the effect of endogenous and exogenous substances on heat-induced aggregation of human serum albumin.
Topics: Acids, Acyclic; Albumins; Anti-Inflammatory Agents, Non-Steroidal; Bilirubin; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dicarboxylic Acids; Diclofenac; Electrophoresis, Polyacrylamide Gel; Hot Temperature; Humans; Ibuprofen; In Vitro Techniques; Naproxen; Nephelometry and Turbidimetry; Protein Denaturation; Serum Albumin; Sodium Chloride | 1998 |
Gastrointestinal toxicity of over-the-counter analgesics.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Gastric Mucosa; Humans; Ibuprofen; Intestinal Mucosa; Intestines; Ketoprofen; Naproxen; Nonprescription Drugs; Peptic Ulcer; Stomach; Time Factors | 1998 |
Pseudomethemoglobinemia: a case report and review of sulfhemoglobinemia.
Topics: Acetaminophen; Adolescent; Cimetidine; Diagnosis, Differential; Female; Humans; Ibuprofen; Methemoglobinemia; Naproxen; Oximetry; Suicide, Attempted; Sulfhemoglobinemia | 1998 |
Naproxen sodium did not lead to substantially more upper gastrointestinal tract bleeding than ibuprofen during short term use as an analgesic.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Databases, Factual; Female; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Male; Naproxen; Nonprescription Drugs; Risk | 1998 |
Effect of chemical structure on the release of certain propionic acid derivatives from their dosage forms.
Topics: Capsules; Chemical Phenomena; Chemistry, Physical; Dosage Forms; Drug Compounding; Drug Stability; Drug Storage; Flurbiprofen; Humans; Ibuprofen; Ketoprofen; Molecular Structure; Naproxen; Propionates; Suppositories | 1998 |
Kinetic basis for selective inhibition of cyclo-oxygenases.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Ibuprofen; Indomethacin; Inhibitory Concentration 50; Isoenzymes; Kinetics; Male; Membrane Proteins; Mice; Naproxen; Oxygen; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sheep; Structure-Activity Relationship; Sulfonamides; Tetramethylphenylenediamine; Thermodynamics | 1999 |
Low-dose diclofenac, naproxen, and ibuprofen cohort study.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Cohort Studies; Diclofenac; Dose-Response Relationship, Drug; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Female; Gastrointestinal Hemorrhage; Hematologic Diseases; Humans; Ibuprofen; Male; Middle Aged; Naproxen | 1999 |
Mechanism of drug release from poly(L-lactic acid) matrix containing acidic or neutral drugs.
Topics: Biodegradation, Environmental; Crystallization; Delayed-Action Preparations; Diffusion; Griseofulvin; Hydrogen-Ion Concentration; Ibuprofen; Indomethacin; Lactic Acid; Naproxen; Polymers; Progesterone; Solubility; Testosterone | 1999 |
Hydrogen-stretching vibrational circular dichroism spectroscopy: absolute configuration and solution conformation of selected pharmaceutical molecules.
Topics: Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Circular Dichroism; Flecainide; Hydrogen; Ibuprofen; Models, Molecular; Molecular Conformation; Molecular Structure; Naphthalenes; Naproxen; Propranolol; Pyrrolidinones; Quinidine; Vibration | 1999 |
Cleavage of tertiary amidomethyl ester prodrugs of carboxylic acids by rat liver homogenates.
Topics: Amides; Animals; Benzoic Acid; Carboxylic Acids; Clofibric Acid; Diclofenac; Drug Interactions; Esters; Hydrolases; Hydrolysis; Ibuprofen; In Vitro Techniques; Liver; Male; Naproxen; Physostigmine; Proadifen; Probenecid; Prodrugs; Rats; Rats, Sprague-Dawley; Refractometry; Solubility; Structure-Activity Relationship; Time Factors; Valproic Acid | 1999 |
Pharmacoepidemiology of non-steroidal anti-inflammatory drug use in Nottingham general practices.
Topics: Adolescent; Adult; Age Factors; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Prescriptions; Family Practice; Humans; Ibuprofen; Inflammation; Medical Records Systems, Computerized; Middle Aged; Naproxen; Patient Compliance; Pharmacoepidemiology; United Kingdom | 2000 |
Ibuprofen versus other non-steroidal anti-inflammatory drugs: use in general practice and patient perception.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Prescriptions; Humans; Ibuprofen; Medical Records Systems, Computerized; Middle Aged; Naproxen; Patient Satisfaction; Surveys and Questionnaires; United Kingdom | 2000 |
Liquid-phase microextraction and capillary electrophoresis of acidic drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Naproxen | 2000 |
Preference for nonsteroidal antiinflammatory drugs versus acetaminophen and concomitant use of both types of drugs in patients with osteoarthritis.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Data Collection; Diclofenac; Female; Humans; Ibuprofen; Male; Naproxen; Osteoarthritis; Patient Satisfaction; Self Administration; Surveys and Questionnaires | 2000 |
Determination of some antirheumatics by capillary isotachophoresis.
Topics: Antirheumatic Agents; Electrophoresis, Capillary; Fenoprofen; Humans; Ibuprofen; Ketoprofen; Naproxen | 2000 |
Synthesis and characteristics of the human serum albumin-triazine chiral stationary phase.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Atropine; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Fenoprofen; Glutamic Acid; Humans; Ibuprofen; Naproxen; Protein Binding; Serum Albumin; Silicon Dioxide; Spectrophotometry, Ultraviolet; Stereoisomerism; Triazines; Tryptophan; Warfarin | 2000 |
Uniform-sized molecularly imprinted polymers for 2-arylpropionic acid derivatives selectively modified with hydrophilic external layer and their applications to direct serum injection analysis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Ibuprofen; Male; Naproxen; Polymers; Propionates; Rats; Rats, Sprague-Dawley | 2000 |
Treatment of pseudotumors with nonsteroidal antiinflammatory drugs.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Biopsy, Needle; Child; Colonic Diseases; Drug Administration Schedule; Female; Follow-Up Studies; Granuloma, Plasma Cell; Humans; Hydronephrosis; Ibuprofen; Male; Naproxen; Tomography, X-Ray Computed; Treatment Outcome | 2000 |
Analysis of nonsteroidal antiinflammatory drugs in meconium and its relation to persistent pulmonary hypertension of the newborn.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bronchodilator Agents; Extracorporeal Membrane Oxygenation; Female; Gas Chromatography-Mass Spectrometry; Humans; Ibuprofen; Infant, Newborn; Logistic Models; Meconium; Naproxen; Nitric Oxide; Persistent Fetal Circulation Syndrome; Pregnancy; Prenatal Exposure Delayed Effects; Risk | 2001 |
Determination of ibuprofen and naproxen in tablets.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calibration; Electrophoresis; Ibuprofen; Naproxen; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Tablets | 2001 |
[Two complex suicidal poisonings with drugs and their medicolegal aspects].
Topics: Adult; Atenolol; Chromatography, High Pressure Liquid; Diclofenac; Estazolam; Fatal Outcome; Female; Humans; Ibuprofen; Illicit Drugs; Ketoprofen; Male; Metronidazole; Naproxen; Poland; Suicide, Attempted; Theophylline; Tolperisone | 2001 |
I'm taking over-the-counter ibuprofen every day for neck pain. Recently, my doctor gave me a prescription for naproxen for my arthritis. Should I be concerned about taking these two together?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Interactions; Humans; Ibuprofen; Naproxen | 2001 |
Binding constant determination of drugs toward subdomain IIIA of human serum albumin by near-infrared dye-displacement capillary electrophoresis.
Topics: Binding, Competitive; Clofibrate; Coloring Agents; Electrophoresis, Capillary; Humans; Ibuprofen; Imipramine; Indoles; Ketoprofen; Kinetics; Naproxen; Protein Binding; Protein Structure, Tertiary; Quinidine; Serum Albumin; Stereoisomerism; Sulfonic Acids | 2001 |
Nonsteroidal anti-inflammatory drugs for perioperative pain control.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Etodolac; Humans; Ibuprofen; Indomethacin; Ketorolac; Lactones; Nabumetone; Naproxen; Pain, Postoperative; Piroxicam; Pyrazoles; Sulfonamides; Sulfones; Time Factors | 2001 |
Three new vanadyl(IV) complexes with non-steroidal anti-inflammatory drugs (Ibuprofen, Naproxen and Tolmetin). Bioactivity on osteoblast-like cells in culture.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Dose-Response Relationship, Drug; Ibuprofen; Mice; Naproxen; Organometallic Compounds; Osteoblasts; Rats; Spectrum Analysis; Tolmetin; Tumor Cells, Cultured; Vanadates | 2002 |
Hypersensitivity reactions associated with exposure to naproxen and ibuprofen: a cohort study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Drug Hypersensitivity; Hospitalization; Humans; Ibuprofen; Medical Record Linkage; Multivariate Analysis; Naproxen; Scotland | 2001 |
Activation of peroxisome proliferator-activated receptor isoforms and inhibition of prostaglandin H(2) synthases by ibuprofen, naproxen, and indomethacin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Ibuprofen; Indomethacin; Naproxen; Prostaglandin-Endoperoxide Synthases; Protein Isoforms; Rats; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Tumor Cells, Cultured | 2001 |
Non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease: an observational cohort study.
Topics: Age Distribution; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bias; Cause of Death; Cohort Studies; Coronary Disease; Death Certificates; Drug Prescriptions; Female; Humans; Ibuprofen; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Naproxen; Patient Admission; Platelet Aggregation Inhibitors; Registries; Regression Analysis; Risk Factors; Tennessee | 2002 |
Nonsteroidal drugs and Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Naproxen | 2002 |
Characterization, quantification, and bioactivities of anthocyanins in Cornus species.
Topics: Anthocyanins; Antioxidants; Celecoxib; Chromatography, High Pressure Liquid; Cornus; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Fruit; Ibuprofen; Isoenzymes; Lactones; Naproxen; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Sulfones | 2002 |
Awareness and use of over-the-counter pain medications: a survey of emergency department patients.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Aspirin; Drug Utilization; Female; Health Knowledge, Attitudes, Practice; Humans; Ibuprofen; Male; Multivariate Analysis; Naproxen; Nonprescription Drugs; Prospective Studies; Regression Analysis | 2002 |
Trends in medication use for osteoarthritis treatment.
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Drug Utilization; Female; Humans; Ibuprofen; Male; Middle Aged; Nabumetone; Naproxen; Osteoarthritis; United States | 2002 |
Effect of combined chemotherapy and anti-inflammatory drugs on murine schistosomiasis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Helminth; Drug Therapy, Combination; Granuloma; Hypersensitivity; Ibuprofen; Liver; Liver Function Tests; Mice; Naproxen; Praziquantel; Schistosoma mansoni; Schistosomiasis mansoni; Schistosomicides | 2002 |
Bioactivity of alkamides isolated from Echinacea purpurea (L.) Moench.
Topics: Aedes; Amides; Animals; Anti-Inflammatory Agents; Aspirin; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Echinacea; Ibuprofen; Isoenzymes; Lactones; Lethal Dose 50; Naproxen; Phytotherapy; Plant Extracts; Plant Roots; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Sulfones | 2002 |
Effect of inflammatory mediators on the physiology of the human Fallopian tube.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Diclofenac; Dose-Response Relationship, Drug; Electric Conductivity; Electrophysiology; Epithelial Cells; Fallopian Tubes; Female; Histamine; Humans; Ibuprofen; Indomethacin; Inflammation Mediators; Muscle Contraction; Muscle, Smooth; Naproxen; Pelvic Pain; Platelet Activating Factor | 2002 |
Kinetics and hydrolysis mechanism of polymeric prodrugs containing ibuprofen, ketoprofen, and naproxen as pendent agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Stability; Edema; Female; Hydrogen-Ion Concentration; Hydrolysis; Ibuprofen; Ketoprofen; Kinetics; Methacrylates; Naproxen; Polymers; Prodrugs; Rats; Rats, Wistar; Solubility; Treatment Outcome | 2002 |
Intercalation and controlled release of pharmaceutically active compounds from a layered double hydroxide.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Diclofenac; Gemfibrozil; Hydrogen-Ion Concentration; Hydroxides; Ibuprofen; Naproxen; ortho-Aminobenzoates; Phenylacetates; Valproic Acid | 2001 |
Superior effectiveness of ibuprofen compared with other NSAIDs for reducing the survival of human prostate cancer cells.
Topics: Acetaminophen; Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Division; Humans; Ibuprofen; In Situ Nick-End Labeling; Male; Mice; Naproxen; Nitrobenzenes; Prostatic Neoplasms; Sulfonamides; Tumor Cells, Cultured | 2002 |
COX-2 selective non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Coronary Disease; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Humans; Ibuprofen; Isoenzymes; Lactones; Male; Medicaid; Membrane Proteins; Middle Aged; Naproxen; Product Surveillance, Postmarketing; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Regression Analysis; Retrospective Studies; Risk Factors; Sulfonamides; Sulfones; Tennessee | 2002 |
In vitro detection of (S)-naproxen and ibuprofen binding to plaques in the Alzheimer's brain using the positron emission tomography molecular imaging probe 2-(1-[6-[(2-[(18)F]fluoroethyl)(methyl)amino]-2-naphthyl]ethylidene)malononitrile.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Anti-Inflammatory Agents, Non-Steroidal; Autoradiography; Binding Sites; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Female; Humans; Ibuprofen; In Vitro Techniques; Naproxen; Nitriles; Plaque, Amyloid; Radiopharmaceuticals; Tomography, Emission-Computed | 2003 |
Rofecoxib in rheumatoid arthritis: new indication. No better that other NSAIDS.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Contraindications; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Humans; Ibuprofen; Lactones; Naproxen; Sulfonamides; Treatment Outcome; United States | 2003 |
Complexation trends and binding constants between dextrin oligomers and small molecules as measured through affinity capillary electrophoresis.
Topics: Analgesics; Carbohydrate Sequence; Dextrins; Electrophoresis, Capillary; Fluorescent Dyes; Glucans; Ibuprofen; Ketoprofen; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Naproxen; Oligosaccharides; Protein Binding; Pyrenes; Staining and Labeling | 2003 |
Persistence with COX-2 inhibitors in managed care: an analysis of claims data.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Drug Utilization Review; Female; Health Care Costs; Humans; Ibuprofen; Insurance Claim Review; Isoenzymes; Lactones; Male; Managed Care Programs; Membrane Proteins; Middle Aged; Naproxen; Patient Compliance; Proportional Hazards Models; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Regression Analysis; Sulfonamides; Sulfones; United States | 2003 |
Incidence of outpatient physician claims for upper gastrointestinal symptoms among new users of celecoxib, ibuprofen, and naproxen in an insured population in the United States.
Topics: Abdominal Pain; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Dyspepsia; Female; Humans; Ibuprofen; Incidence; Insurance Claim Reporting; Male; Middle Aged; Naproxen; Nausea; Outpatients; Poisson Distribution; Proportional Hazards Models; Pyrazoles; Risk Factors; Sulfonamides; United States; Vomiting | 2003 |
Potential interaction between acenocoumarol and diclofenac, naproxen and ibuprofen and role of CYP2C9 genotype.
Topics: Acenocoumarol; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Aryl Hydrocarbon Hydroxylases; Chi-Square Distribution; Cohort Studies; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C9; Diclofenac; Drug Interactions; Female; Genotype; Humans; Ibuprofen; International Normalized Ratio; Male; Middle Aged; Naproxen; Retrospective Studies; Sex Factors; Time Factors; Warfarin | 2004 |
Application of capillary electrophoresis with different sample stacking strategies for the determination of a group of nonsteroidal anti-inflammatory drugs in the low microg x L(-1) concentration range.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Electrophoresis, Capillary; Fenoprofen; Ibuprofen; Ketoprofen; Naproxen; Water | 2004 |
Longer use of COX-2-specific inhibitors compared to nonspecific nonsteroidal antiinflammatory drugs: a longitudinal study of 3639 patients in community practice.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Community Health Services; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Fibromyalgia; Follow-Up Studies; Humans; Ibuprofen; Isoenzymes; Lactones; Longitudinal Studies; Male; Membrane Proteins; Middle Aged; Naproxen; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Sulfones; Surveys and Questionnaires | 2004 |
Assessment of arginine 97 and lysine 72 as determinants of substrate specificity in cytochrome P450 2C9 (CYP2C9).
Topics: Animals; Arginine; Aryl Hydrocarbon Hydroxylases; Base Sequence; Binding Sites; Cytochrome P-450 CYP2C9; Diclofenac; Escherichia coli; Gene Expression; Hemeproteins; Holoenzymes; Humans; Ibuprofen; Lysine; Models, Molecular; Mutagenesis, Site-Directed; NADPH-Ferrihemoprotein Reductase; Naproxen; Peptide Fragments; Recombinant Proteins; Sequence Homology, Nucleic Acid; Substrate Specificity | 2004 |
Over-the-counter pain reliever and aspirin use within a sample of long-term cyclooxygenase 2 users.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Nonprescription Drugs; Pyrazoles; Sulfonamides | 2004 |
Nonsteroidal antiinflammatory drugs and the risk of myocardial infarction in the general population.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiotonic Agents; Case-Control Studies; Cohort Studies; Comorbidity; Coronary Disease; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Drug Synergism; Drug Utilization; Female; Follow-Up Studies; Humans; Ibuprofen; Lactones; Male; Middle Aged; Myocardial Infarction; Naproxen; Odds Ratio; Risk Factors; Spain; Sulfones | 2004 |
Nanosizing drug particles in supercritical fluid processing.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Ibuprofen; Nanotechnology; Naproxen; Particle Size; Solubility | 2004 |
Synthesis of precursor of anti-inflammatory agents by using highly reactive zinc.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Catalysis; Electrolysis; Humans; Ibuprofen; Naphthalenes; Naproxen; Prodrugs; Propionates; Suprofen; Zinc | 2004 |
Evidence in practice--number 3: Cox 2 inhibitors.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Diclofenac; Evidence-Based Medicine; Humans; Ibuprofen; Middle Aged; Naproxen; Organic Chemicals; Osteoarthritis; Stomach Ulcer | 2004 |
Sulfone COX-2 inhibitors increase susceptibility of human LDL and plasma to oxidative modification: comparison to sulfonamide COX-2 inhibitors and NSAIDs.
Topics: Animals; Antioxidants; Celecoxib; Cholesterol, LDL; Chromans; Cyclooxygenase Inhibitors; Diclofenac; Humans; Ibuprofen; Isoprostanes; Isoxazoles; Lactones; Meloxicam; Naproxen; Oxidation-Reduction; Pyrazoles; Sulfonamides; Sulfones; Thiazines; Thiazoles | 2004 |
Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Benzothiazoles; Biphenyl Compounds; Blood-Brain Barrier; Brain; Cell Line, Tumor; Congo Red; Curcumin; Diamines; Humans; Ibuprofen; Mice; Mice, Transgenic; Naproxen; Peptide Fragments; Plaque, Amyloid; Protein Binding; Protein Denaturation; Protein Structure, Quaternary; Pyridazines; Solubility; Thiazoles | 2005 |
Nonprescription dental pain relief.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Humans; Ibuprofen; Naproxen; Toothache | 2004 |
Tracking acidic pharmaceuticals, caffeine, and triclosan through the wastewater treatment process.
Topics: Caffeine; Diclofenac; Ibuprofen; Ketoprofen; Meclofenamic Acid; Models, Chemical; Naproxen; Pharmaceutical Preparations; Triclosan; Waste Disposal, Fluid; Water Pollutants, Chemical | 2005 |
Patients exposed to rofecoxib and celecoxib have different odds of nonfatal myocardial infarction.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bias; Case-Control Studies; Celecoxib; Confounding Factors, Epidemiologic; Cyclooxygenase Inhibitors; Diclofenac; Female; Humans; Ibuprofen; Lactones; Male; Middle Aged; Myocardial Infarction; Naproxen; Odds Ratio; Pyrazoles; Risk Factors; Sulfonamides; Sulfones | 2005 |
Cellular mechanisms of acetaminophen: role of cyclo-oxygenase.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Cell Line; Cyclooxygenase Inhibitors; Diclofenac; Enzyme Activation; Humans; Ibuprofen; Indomethacin; Lactones; Lung; Naproxen; Oxidation-Reduction; Prostaglandin-Endoperoxide Synthases; Protein Biosynthesis; Sulfones; tert-Butylhydroperoxide; Transcription, Genetic | 2005 |
[Extra-thermodynamic properties of 2-arylpropionic acids on a chiral-AGP column by high performance liquid chromatography].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Ibuprofen; Naproxen; Propionates; Stereoisomerism; Thermodynamics | 2004 |
Ask the doctor. I am a 60-year-old man with several risk factors for heart disease. I take Aleve twice a day. Do I still need to take aspirin, or is the Aleve enough? I often take ibuprofen for my headaches or aching back. Now my doctor wants me to start
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Drug Interactions; Humans; Ibuprofen; Male; Middle Aged; Myocardial Infarction; Naproxen | 2005 |
Determination of protein-ligand binding affinity by NMR: observations from serum albumin model systems.
Topics: Animals; Calorimetry; Cattle; Ibuprofen; Ligands; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Naproxen; Protein Binding; Proteins; Salicylates; Serum Albumin; Tryptophan; Warfarin | 2005 |
Measuring the mass of an electron by LC/TOF-MS: a study of "twin ions".
Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Carbon Dioxide; Chromatography, Liquid; Diclofenac; Electrons; Formates; Ibuprofen; Ions; Naproxen; Protons; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2005 |
Interactions of poly(vinylpyrrolidone) with ibuprofen and naproxen: experimental and modeling studies.
Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Drug Interactions; Ibuprofen; Magnetic Resonance Imaging; Microscopy, Electron, Scanning; Models, Molecular; Naproxen; Povidone; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Technology, Pharmaceutical; X-Ray Diffraction | 2005 |
Occurrence of acidic pharmaceuticals in raw and treated sewages and in receiving waters.
Topics: Bezafibrate; Diclofenac; Environmental Pollutants; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Molecular Structure; Naproxen; Sewage; Water | 2005 |
Sensing of antipyretic carboxylates by simple chromogenic calix[4]pyrroles.
Topics: Analgesics, Non-Narcotic; Animals; Anions; Biosensing Techniques; Blood Proteins; Calixarenes; Carboxylic Acids; Humans; Ibuprofen; Naproxen; Nuclear Magnetic Resonance, Biomolecular; Porphyrins; Salicylates; Serum Albumin, Bovine; Spectrophotometry | 2005 |
Pathways and metabolites of microbial degradation of selected acidic pharmaceutical and their occurrence in municipal wastewater treated by a membrane bioreactor.
Topics: Aerobiosis; Amides; Bezafibrate; Biodegradation, Environmental; Bioreactors; Cities; Diclofenac; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Sewage; Spectrometry, Mass, Electrospray Ionization; Time Factors; Waste Disposal, Fluid; Water Pollutants, Chemical | 2005 |
Multiple ligand binding sites on A beta(1-40) fibrils.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Binding Sites; Congo Red; Fluorescent Dyes; Humans; Ibuprofen; Ligands; Models, Chemical; Molecular Structure; Naproxen; Peptide Fragments; Protein Binding; Thiazoles | 2005 |
Photodegradation of common environmental pharmaceuticals and estrogens in river water.
Topics: Chromatography, High Pressure Liquid; Environmental Monitoring; Estrogens; Gemfibrozil; Half-Life; Ibuprofen; Ketoprofen; Naproxen; Oxygen; Pharmaceutical Preparations; Photolysis; Propranolol; Rivers; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Water Pollutants, Chemical | 2005 |
Is there an association between the use of different types of nonsteroidal antiinflammatory drugs and radiologic progression of osteoarthritis? The Rotterdam Study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Disease Progression; Female; Follow-Up Studies; Humans; Ibuprofen; Logistic Models; Male; Middle Aged; Naproxen; Netherlands; Osteoarthritis, Hip; Osteoarthritis, Knee; Pharmacies; Piroxicam; Radiography; Risk Factors | 2005 |
Drug entrapment in silica microspheres through a single step sol-gel process and in vitro release behavior.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Gels; Ibuprofen; In Vitro Techniques; Materials Testing; Microspheres; Naproxen; Particle Size; Silicon Dioxide | 2006 |
Patterns of use and public perception of over-the-counter pain relievers: focus on nonsteroidal antiinflammatory drugs.
Topics: Acetaminophen; Adult; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Data Collection; Female; Health Education; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Nonprescription Drugs; Pain; Patient Compliance; Public Opinion; Self Medication; United States | 2005 |
Risk of serious upper gastrointestinal toxicity with over-the-counter nonaspirin nonsteroidal anti-inflammatory drugs.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Gastrointestinal Diseases; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Nonprescription Drugs; Random Allocation; Risk Factors; Upper Gastrointestinal Tract | 2005 |
[Study results of routine clinical practice. Do rheumatism patients get substandard care?].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclooxygenase 2 Inhibitors; Germany; Humans; Ibuprofen; Myocardial Infarction; Naproxen; Peptic Ulcer; Quality Assurance, Health Care; Retrospective Studies; Risk Assessment; Risk Factors | 2005 |
Drug testing. Massive trial of Celebrex seeks to settle safety concerns.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Confounding Factors, Epidemiologic; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Interactions; Heart Diseases; Humans; Ibuprofen; Membrane Proteins; Naproxen; Pyrazoles; Randomized Controlled Trials as Topic; Research Design; Sulfonamides | 2005 |
Competitive binding of ibuprofen and naproxen to bovine serum albumin : modified form of drug-drug displacement interaction at the binding site.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Binding, Competitive; Cattle; Drug Interactions; Ibuprofen; Naproxen; Serum Albumin | 2005 |
Comparative assessment of two indices of drug induced permeability changes in the perfused rat intestine.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Glycine; Ibuprofen; In Vitro Techniques; Intestinal Mucosa; Intestines; Ketoprofen; Naproxen; Permeability; Phenylalanine; Polyethylene Glycols; Rats | 2006 |
[Analysis of the use and adverse effects of non-steroidal anti-inflammatory drugs: a pilot study].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Utilization; Female; History, 18th Century; Humans; Ibuprofen; Male; Naproxen; Rheumatic Diseases | 2006 |
Accumulation of non-steroidal anti-inflammatory drugs by gingival fibroblasts.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport, Active; Fibroblasts; Gingiva; Humans; Hydrogen-Ion Concentration; Ibuprofen; Naproxen; Tumor Necrosis Factor-alpha | 2006 |
Temporal relationship between use of NSAIDs, including selective COX-2 inhibitors, and cardiovascular risk.
Topics: Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Celecoxib; Cohort Studies; Cyclooxygenase 2 Inhibitors; Etodolac; Female; Humans; Ibuprofen; Lactones; Male; Middle Aged; Naproxen; Pyrazoles; Sulfonamides; Sulfones; Time Factors; United States; Veterans | 2006 |
Chondroitin sulfate-based anti-inflammatory macromolecular prodrugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Carrageenan; Chemical Phenomena; Chemistry, Physical; Chondroitin ABC Lyase; Chondroitin Sulfates; Edema; Excipients; Hydrolysis; Ibuprofen; Ketoprofen; Magnetic Resonance Spectroscopy; Male; Naproxen; Polyethylene Glycols; Prodrugs; Rats; Rats, Wistar; Solubility; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared | 2006 |
Quantitative assessment of the gastrointestinal and cardiovascular risk-benefit of celecoxib compared to individual NSAIDs at the population level.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cardiovascular Diseases; Celecoxib; Computer Simulation; Coronary Disease; Cyclooxygenase Inhibitors; Diclofenac; Female; Heart Failure; Humans; Ibuprofen; Male; Middle Aged; Models, Statistical; Naproxen; Peptic Ulcer; Population Surveillance; Pyrazoles; Risk Assessment; Risk Factors; Stroke; Sulfonamides; United States | 2007 |
Gastrointestinal complications of over-the-counter nonsteroidal antiinflammatory drugs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Child, Preschool; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Infant; Infant, Newborn; Insurance Claim Review; Male; Middle Aged; Naproxen; Odds Ratio; Retrospective Studies | 2006 |
Overuse of over-the-counter analgesics by emergency department patients.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Aspirin; Cross-Sectional Studies; Drug Utilization; Emergency Service, Hospital; Female; Hospitals, University; Hospitals, Urban; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Nonprescription Drugs; United States | 2006 |
Signal enhancement in HPLC/microcoil NMR using automated column trapping.
Topics: Chromatography, High Pressure Liquid; Ibuprofen; Magnetic Resonance Spectroscopy; Naproxen; Phenylbutazone | 2006 |
Factors affecting the formation of eutectic solid dispersions and their dissolution behavior.
Topics: Drug Carriers; Fenofibrate; Flurbiprofen; Griseofulvin; Ibuprofen; Models, Chemical; Molecular Weight; Naproxen; Polyethylene Glycols; Sodium Dodecyl Sulfate; Solubility; Transition Temperature; Water | 2007 |
Non-carboxylic analogues of arylpropionic acids: synthesis, anti-inflammatory activity and ulcerogenic potential.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Flurbiprofen; Ibuprofen; Male; Naproxen; Propionates; Rats; Stomach Ulcer; Structure-Activity Relationship; Thiadiazoles; Thiazoles | 2007 |
Simultaneous assessment of short-term gastrointestinal benefits and cardiovascular risks of selective cyclooxygenase 2 inhibitors and nonselective nonsteroidal antiinflammatory drugs: an instrumental variable analysis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Lactones; Male; Multivariate Analysis; Myocardial Infarction; Naproxen; Pyrazoles; Rheumatic Diseases; Risk Assessment; Risk Factors; Sulfonamides; Sulfones | 2006 |
New warnings about painkillers, new advice on what you can do.
Topics: Antacids; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Drug Interactions; Humans; Ibuprofen; Lactones; Naproxen; Sulfones | 2006 |
Calculation methods to perform mass balances of micropollutants in sewage treatment plants. application to pharmaceutical and personal care products (PPCPs).
Topics: Algorithms; Benzopyrans; Environmental Monitoring; Estrogens; Household Products; Ibuprofen; Industry; Naproxen; Pharmaceutical Preparations; Sewage; Sulfamethoxazole; Tetrahydronaphthalenes; Waste Disposal, Fluid; Water Pollutants, Chemical | 2007 |
Micellar solubilization of selected non-steroidal therapeutic agents by new surface-active agents of the class of the products of oxyethylation of ursodeoxycholic acid.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Ketoprofen; Micelles; Naproxen; Pharmaceutical Preparations; Solubility; Solutions; Surface-Active Agents; Ursodeoxycholic Acid; Viscosity | 2006 |
Smoking, caffeine, and nonsteroidal anti-inflammatory drugs in families with Parkinson disease.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Beverages; Caffeine; Case-Control Studies; Family Health; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Odds Ratio; Parkinson Disease; Risk Factors; Smoking; Tea | 2007 |
Signal suppression/enhancement in HPLC-ESI-MS/MS from concomitant medications.
Topics: Calibration; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Humans; Ibuprofen; Molecular Structure; Naproxen; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Signal Processing, Computer-Assisted; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2007 |
Genetic susceptibility to nonsteroidal anti-inflammatory drug-related gastroduodenal bleeding: role of cytochrome P450 2C9 polymorphisms.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Case-Control Studies; Celecoxib; Cytochrome P-450 CYP2C9; Diclofenac; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Odds Ratio; Peptic Ulcer; Peptic Ulcer Hemorrhage; Piroxicam; Polymorphism, Single Nucleotide; Pyrazoles; Risk Assessment; Risk Factors; Sulfonamides | 2007 |
Photocatalytic degradation of non-steroidal anti-inflammatory drugs with TiO2 and simulated solar irradiation.
Topics: Aliivibrio fischeri; Anti-Inflammatory Agents, Non-Steroidal; Catalysis; Diclofenac; Ibuprofen; Luminescence; Naproxen; Photolysis; Sunlight; Titanium; Water Pollutants, Chemical | 2008 |
Equilibrium solubilization of lipophilic therapeutic agents by aqueous solutions of products of catalytic oxyethylation of Croda-type lanolin as model excipients of the class of non-ionic surface active agents.
Topics: Administration, Cutaneous; Algorithms; Catalysis; Chemistry, Pharmaceutical; Ethylenes; Excipients; Ibuprofen; Ketoprofen; Lanolin; Models, Chemical; Naproxen; Pharmaceutical Vehicles; Solubility; Solutions; Structure-Activity Relationship; Surface-Active Agents; Thermodynamics; Viscosity; Water | 2007 |
The influence of mobile phase demixion on thin-layer chromatographic enantioseparation of ibuprofen and naproxen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Thin Layer; Circular Dichroism; Ibuprofen; Naproxen; Stereoisomerism | 2007 |
Etoricoxib: new drug. Avoid using cox-2 inhibitors for pain.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cardiovascular Diseases; Clinical Trials as Topic; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Gastrointestinal Diseases; Gout; Humans; Ibuprofen; Naproxen; Pain; Pyridines; Sulfones | 2007 |
Cyclooxygenase-2 inhibitors and most traditional nonsteroidal anti-inflammatory drugs cause similar moderately increased risks of cardiovascular disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Clinical Trials as Topic; Cyclooxygenase 2 Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Humans; Ibuprofen; Meta-Analysis as Topic; Myocardial Infarction; Naproxen; Risk | 2008 |
Patterns of pregnancy exposure to prescription FDA C, D and X drugs in a Canadian population.
Topics: Adult; Albuterol; Contraceptives, Oral; Cross-Sectional Studies; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Female; Gestational Age; Humans; Ibuprofen; Infant, Newborn; Naproxen; Population Surveillance; Pregnancy; Prenatal Exposure Delayed Effects; Saskatchewan; Trimethoprim, Sulfamethoxazole Drug Combination; United States; United States Food and Drug Administration | 2008 |
Design, synthesis and in vitro evaluation of vinyl ether type polymeric prodrugs of ibuprofen, ketoprofen and naproxen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Hydrogen-Ion Concentration; Hydrolysis; Ibuprofen; Ketoprofen; Magnetic Resonance Spectroscopy; Naproxen; Polymers; Prodrugs; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Vinyl Compounds | 2008 |
Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity.
Topics: Amyloid beta-Peptides; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Furans; Hippocampus; Ibuprofen; Inflammation Mediators; Interleukin-1beta; Male; Memory; Memory Disorders; Mice; Mice, Inbred C57BL; Naproxen; Neuronal Plasticity; Peptide Fragments; Rats; Synapses; Tumor Necrosis Factor-alpha | 2008 |
Identification of the carboxylic acid functionality by using electrospray ionization and ion-molecule reactions in a modified linear quadrupole ion trap mass spectrometer.
Topics: Acetates; Anti-Inflammatory Agents, Non-Steroidal; Borates; Carboxylic Acids; Cations, Monovalent; Ibuprofen; Ketoprofen; Methanol; Naproxen; Sodium; Spectrometry, Mass, Electrospray Ionization | 2008 |
Solubilizing and lithogenolitic properties of water solutions of non-ionic surfactants of cholesterol oxyethylenation products.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Catalysis; Cholesterol; Ethylene Oxide; Ibuprofen; Ions; Ketoprofen; Lithiasis; Micelles; Models, Theoretical; Naproxen; Solubility; Solutions; Surface-Active Agents; Water | 2007 |
Identification and quantification of ibuprofen, naproxen, ketoprofen and diclofenac present in waste-waters, as their trimethylsilyl derivatives, by gas chromatography mass spectrometry.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Gas Chromatography-Mass Spectrometry; Hungary; Ibuprofen; Ketoprofen; Naproxen; Trimethylsilyl Compounds; Waste Disposal, Fluid; Water Pollutants, Chemical | 2008 |
Monitoring the synthetic procedures of commercial drugs by 2H NMR spectroscopy: the case of ibuprofen and naproxen.
Topics: Deuterium; Ibuprofen; Magnetic Resonance Spectroscopy; Naproxen; Pharmaceutical Preparations | 2008 |
Does the varied use of NSAIDs explain the differences in the risk of myocardial infarction?
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Administration Schedule; Epidemiologic Methods; Female; Humans; Ibuprofen; Male; Middle Aged; Myocardial Infarction; Naproxen; Sex Factors; Time Factors | 2008 |
Chemoenzymatic and microbial dynamic kinetic resolutions.
Topics: Alcohols; Carboxylic Acids; Catalysis; Chemistry, Organic; Enzymes; Esterification; Esters; Fenoprofen; Fungal Proteins; Hydrolysis; Ibuprofen; Kinetics; Molecular Structure; Naproxen; Stereoisomerism; Suprofen | 2009 |
Advances in stir bar sorptive extraction for the determination of acidic pharmaceuticals in environmental water matrices Comparison between polyurethane and polydimethylsiloxane polymeric phases.
Topics: Chromatography, High Pressure Liquid; Diclofenac; Dimethylpolysiloxanes; Gemfibrozil; Ibuprofen; Mefenamic Acid; Naproxen; Polyurethanes; Reproducibility of Results; Water Pollutants, Chemical; Water Purification | 2008 |
Supramolecular solid-phase extraction of ibuprofen and naproxen from sewage based on the formation of mixed supramolecular aggregates prior to their liquid chromatographic/photometric determination.
Topics: Chromatography, Liquid; Ibuprofen; Naproxen; Photometry; Sewage; Sodium Dodecyl Sulfate; Solid Phase Extraction; Spain; Water Pollutants, Chemical | 2008 |
Removal of selected pharmaceuticals by chlorination, coagulation-sedimentation and powdered activated carbon treatment.
Topics: Antipyrine; Charcoal; Clofibric Acid; Diclofenac; Fenoprofen; Gemfibrozil; Halogenation; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Water Pollutants, Chemical; Water Purification; Water Supply | 2008 |
Estimation of drug solubility in polymers via differential scanning calorimetry and utilization of the fox equation.
Topics: Algorithms; Calorimetry, Differential Scanning; Chromatography, High Pressure Liquid; Complex Mixtures; Crystallization; Glass; Ibuprofen; Indomethacin; Molecular Structure; Naproxen; Pharmaceutical Preparations; Polyethylene Glycols; Polymers; Solubility; Thermography; Transition Temperature | 2009 |
Skin disposition of menthol after its application in the presence of drug substances.
Topics: Adult; Epidermis; Female; Humans; Ibuprofen; Menthol; Middle Aged; Naproxen; Salicylates; Skin; Tartrates | 2008 |
Effect of chirality on PVP/drug interaction within binary physical mixtures of ibuprofen, ketoprofen, and naproxen: a DSC study.
Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Hot Temperature; Ibuprofen; Ketoprofen; Molecular Structure; Naproxen; Povidone; Stereoisomerism | 2009 |
Novel beta-cyclodextrin derivative functionalized polymethacrylate-based monolithic columns for enantioselective separation of ibuprofen and naproxen enantiomers in capillary electrochromatography.
Topics: beta-Cyclodextrins; Capillary Electrochromatography; Electrolytes; Equipment Reuse; Ibuprofen; Methylmethacrylates; Naproxen; Reproducibility of Results; Solvents; Stereoisomerism | 2009 |
Assessment of the pharmaceutical active compounds removal in wastewater treatment systems at enantiomeric level. Ibuprofen and naproxen.
Topics: Ibuprofen; Naproxen; Stereoisomerism; Waste Disposal, Fluid; Water Purification | 2009 |
The membrane-activity of Ibuprofen, Diclofenac, and Naproxen: a physico-chemical study with lecithin phospholipids.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry; Calorimetry, Differential Scanning; Diclofenac; Dimyristoylphosphatidylcholine; Fluorescence Resonance Energy Transfer; Ibuprofen; Lecithins; Liposomes; Naproxen; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Thermodynamics | 2009 |
Determination of widely used non-steroidal anti-inflammatory drugs in water samples by in situ derivatization, continuous hollow fiber liquid-phase microextraction and gas chromatography-flame ionization detector.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Gas; Drug Residues; Flame Ionization; Ibuprofen; Ketoprofen; Naproxen; Reproducibility of Results; Water Pollutants, Chemical | 2009 |
Convenient synthesis of Ibuprofen and naproxen aminoacyl, dipeptidoyl and ester derivatives.
Topics: Amino Acids; Anti-Inflammatory Agents, Non-Steroidal; Dipeptides; Esters; Ibuprofen; Naproxen; Prodrugs; Stigmasterol | 2009 |
Preparation and characterization of nanoparticles based on dextran-drug conjugates.
Topics: Dextrans; Drug Carriers; Drug Stability; Ibuprofen; Microscopy, Electron, Scanning; Molecular Structure; Nanoparticles; Naproxen; Particle Size | 2009 |
Differences in the interaction between aryl propionic acid derivatives and poly(vinylpyrrolidone) K30: A multi-methodological approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Carbon Isotopes; Crystallization; Drug Stability; Flurbiprofen; Hot Temperature; Humidity; Hydrogen Bonding; Ibuprofen; Ketoprofen; Magnetic Resonance Spectroscopy; Molecular Structure; Molecular Weight; Naproxen; Phase Transition; Phenylbutyrates; Polymers; Povidone; Static Electricity; X-Ray Diffraction | 2009 |
Degradation and adsorption of selected pharmaceuticals and personal care products (PPCPs) in agricultural soils.
Topics: Adsorption; Benzhydryl Compounds; Biodegradation, Environmental; Clofibric Acid; Diclofenac; Household Products; Ibuprofen; Naproxen; Pharmaceutical Preparations; Phenols; Soil; Soil Microbiology; Soil Pollutants; Triclosan | 2009 |
NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cell Cycle; Disease Models, Animal; Female; Humans; Ibuprofen; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microglia; Mutation; Naproxen; Neurons; Protein Processing, Post-Translational; Recombinant Proteins | 2009 |
Cardiovascular risks of nonsteroidal antiinflammatory drugs in patients after hospitalization for serious coronary heart disease.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Celecoxib; Cohort Studies; Coronary Artery Disease; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Follow-Up Studies; Hospitalization; Humans; Ibuprofen; Incidence; Lactones; Male; Middle Aged; Myocardial Infarction; Naproxen; Outpatients; Pyrazoles; Retrospective Studies; Risk Factors; Stroke; Sulfonamides; Sulfones; Tennessee | 2009 |
A molecular mechanism for ibuprofen-mediated RhoA inhibition in neurons.
Topics: Anilides; Animals; Animals, Newborn; Benzophenones; Cells, Cultured; Cerebellum; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Ganglia, Spinal; Gene Expression Regulation; Hypoglycemic Agents; Ibuprofen; Mice; Mice, Inbred C57BL; Naproxen; Neurites; Neurons; PC12 Cells; PPAR gamma; Rats; rhoA GTP-Binding Protein; RNA, Small Interfering; Signal Transduction; Transfection; Tubulin; Tyrosine | 2010 |
Second interlaboratory exercise on non-steroidal anti-inflammatory drug analysis in environmental aqueous samples.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemistry Techniques, Analytical; Diclofenac; Environmental Monitoring; Filtration; Gas Chromatography-Mass Spectrometry; Ibuprofen; Ketoprofen; Naproxen; Reproducibility of Results; Water Pollutants, Chemical; Water Purification | 2010 |
Periorbital edema associated with separate courses of ibuprofen and naproxen.
Topics: Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Edema; Eye Diseases; Female; Humans; Ibuprofen; Naproxen; Osteoarthritis | 2010 |
The role of the acquisition methods in the analysis of the non-steroidal anti-inflammatory drugs in Danube River by gas chromatography-mass spectrometry.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Gas Chromatography-Mass Spectrometry; Ibuprofen; Ketoprofen; Limit of Detection; Naproxen; Rivers; Water Pollutants, Chemical | 2010 |
Binding of nonsteroidal anti-inflammatory drugs to Abeta fibril.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Binding, Competitive; Computer Simulation; Humans; Ibuprofen; Kinetics; Models, Molecular; Molecular Sequence Data; Molecular Structure; Naproxen; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Temperature | 2010 |
APP intracellular domain impairs adult neurogenesis in transgenic mice by inducing neuroinflammation.
Topics: Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ibuprofen; Immunohistochemistry; In Vitro Techniques; Inflammation; Male; Mice; Mice, Transgenic; Naproxen; Nerve Tissue Proteins; Neurogenesis; Nuclear Proteins | 2010 |
Occurrence, temporal evolution and risk assessment of pharmaceutically active compounds in Doñana Park (Spain).
Topics: Environmental Monitoring; Estrogens; Fresh Water; Gemfibrozil; Ibuprofen; Industrial Waste; Naproxen; Pharmaceutical Preparations; Propranolol; Risk Assessment; Rivers; Seasons; Spain; Time Factors | 2010 |
Determination of non-steroidal anti-inflammatory drugs in sewage sludge by direct hollow fiber supported liquid membrane extraction and liquid chromatography-mass spectrometry.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Fractionation; Chromatography, Liquid; Diclofenac; Ibuprofen; Ketoprofen; Mass Spectrometry; Naproxen; Reproducibility of Results; Sewage | 2010 |
Capacity of a horizontal subsurface flow constructed wetland system for the removal of emerging pollutants: an injection experiment.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Environmental Restoration and Remediation; Ibuprofen; Naproxen; Perfume; Tetrahydronaphthalenes; Waste Disposal, Fluid; Water Movements; Water Pollutants, Chemical; Wetlands | 2010 |
A primer on pain relief.
Topics: Acetaminophen; Analgesia; Analgesics; Aspirin; Humans; Ibuprofen; Naproxen; Nonprescription Drugs; Pain | 2010 |
Nonsteroidal anti-inflammatory drug naproxen destabilizes Aβ amyloid fibrils: a molecular dynamics investigation.
Topics: Amino Acid Sequence; Amyloid; Amyloid beta-Peptides; Anti-Inflammatory Agents, Non-Steroidal; Ibuprofen; Models, Molecular; Molecular Dynamics Simulation; Molecular Sequence Data; Naproxen; Protein Conformation; Solvents | 2010 |
Demographic, medical, and behavioral characteristics associated with over the counter non-steroidal anti-inflammatory drug use in a population-based cohort: results from the Multi-Ethnic Study of Atherosclerosis.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Ethnicity; Female; Health Status; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Nonprescription Drugs; Pain; Prescription Drugs; United States | 2011 |
Sorption and degradation of wastewater-associated non-steroidal anti-inflammatory drugs and antibiotics in soils.
Topics: Adsorption; Aerobiosis; Agricultural Irrigation; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Biodegradation, Environmental; Diclofenac; Ibuprofen; Naproxen; Soil; Soil Microbiology; Sulfamethoxazole; Trimethoprim; Water Pollutants, Chemical | 2011 |
Uptake from water, biotransformation, and biliary excretion of pharmaceuticals by rainbow trout.
Topics: Animals; Bile; Biotransformation; Bisoprolol; Carbamazepine; Diclofenac; Fresh Water; Ibuprofen; Naproxen; Oncorhynchus mykiss; Pharmaceutical Preparations; Water Pollutants, Chemical | 2011 |
Duration of treatment with nonsteroidal anti-inflammatory drugs and impact on risk of death and recurrent myocardial infarction in patients with prior myocardial infarction: a nationwide cohort study.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Comorbidity; Contraindications; Cyclooxygenase 2 Inhibitors; Denmark; Diclofenac; Female; Humans; Ibuprofen; Incidence; Male; Middle Aged; Myocardial Infarction; Naproxen; Prognosis; Proportional Hazards Models; Recurrence; Registries; Risk Factors | 2011 |
Harmful effects of NSAIDs among patients with hypertension and coronary artery disease.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure; Celecoxib; Confounding Factors, Epidemiologic; Coronary Artery Disease; Diclofenac; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypertension; Ibuprofen; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Multicenter Studies as Topic; Multivariate Analysis; Myocardial Infarction; Naproxen; Odds Ratio; Proportional Hazards Models; Pyrazoles; Randomized Controlled Trials as Topic; Stroke; Sulfonamides; Verapamil | 2011 |
Enantioselective analysis of ibuprofen, ketoprofen and naproxen in wastewater and environmental water samples.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Gas Chromatography-Mass Spectrometry; Ibuprofen; Ketoprofen; Linear Models; Naproxen; Reproducibility of Results; Sewage; Solid Phase Extraction; Stereoisomerism; Tandem Mass Spectrometry; Waste Disposal, Fluid; Water Pollutants, Chemical | 2011 |
Biotransformation of three pharmaceutical active compounds by the fungus Phanerochaete chrysosporium in a fed batch stirred reactor under air and oxygen supply.
Topics: Air; Anti-Inflammatory Agents; Batch Cell Culture Techniques; Biodegradation, Environmental; Bioreactors; Biotransformation; Diclofenac; Ibuprofen; Kinetics; Naproxen; Oxidation-Reduction; Oxygen; Phanerochaete; Water Pollutants, Chemical | 2012 |
Validation and use of in vivo solid phase micro-extraction (SPME) for the detection of emerging contaminants in fish.
Topics: Animals; Atrazine; Benzhydryl Compounds; Carbamazepine; Diclofenac; Environmental Monitoring; Fishes; Fluoxetine; Gemfibrozil; Ibuprofen; Naproxen; Phenols; Solid Phase Extraction; Solid Phase Microextraction; Waste Disposal, Fluid; Water Pollutants, Chemical | 2011 |
Enantiospecific fate of ibuprofen, ketoprofen and naproxen in a laboratory-scale membrane bioreactor.
Topics: Bioreactors; Ibuprofen; Ketoprofen; Laboratories; Membranes, Artificial; Naproxen; Reference Standards; Stereoisomerism; Tandem Mass Spectrometry; Waste Disposal, Fluid | 2011 |
NSAID-sensitive antihistamine-induced urticaria/angioedema.
Topics: Adult; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Drug Hypersensitivity; Histamine H1 Antagonists, Non-Sedating; Humans; Ibuprofen; Loratadine; Male; Naproxen; Skin Tests; Urticaria | 2011 |
Stereoselective inhibitory effect of flurbiprofen, ibuprofen and naproxen on human organic anion transporters hOAT1 and hOAT3.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Flurbiprofen; Humans; Ibuprofen; Inhibitory Concentration 50; Naproxen; Oocytes; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Stereoisomerism; Xenopus laevis | 2011 |
An examination of the thermodynamics of fusion, vaporization, and sublimation of ibuprofen and naproxen by correlation gas chromatography.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Gas; Ibuprofen; Naproxen; Stereoisomerism; Thermodynamics | 2012 |
Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Line, Tumor; Cell Survival; Drug Interactions; Drug Therapy, Combination; Enzyme Inhibitors; Female; HEK293 Cells; Humans; Hydrolysis; Ibuprofen; Indomethacin; Inhibitory Concentration 50; Kinetics; Mice; Mice, Inbred BALB C; Mice, Nude; Naproxen; Nitrophenols; Organophosphates; Organophosphorus Compounds; Phenylglyoxal; Stomach Neoplasms; Sulindac; Transfection; Valproic Acid; Xenograft Model Antitumor Assays | 2012 |
Effect of carboxylic acid on micelles of a neutral amphiphilic dendro-calix[4]arene.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calixarenes; Carboxylic Acids; Hydrogen Bonding; Ibuprofen; Micelles; Naproxen; Phenols; Solubility; Surface-Active Agents; Water | 2012 |
Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; ATP-Binding Cassette Transporters; Biological Transport, Active; Cytochrome P-450 Enzyme System; Diclofenac; Electron Transport; Genes, MDR; Ibuprofen; Indomethacin; Ketoprofen; Ketorolac; Mitochondria; Naproxen; Reactive Oxygen Species; Sulindac; Tolmetin; Yeasts | 2012 |
A connection between the binding properties of imprinted and nonimprinted polymers: a change of perspective in molecular imprinting.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Ibuprofen; Molecular Imprinting; Naproxen; Polymerization; Polymers | 2012 |
Emerging pollutants in sewage, surface and drinking water in Galicia (NW Spain).
Topics: Atenolol; Benzophenones; Diclofenac; Drinking Water; Environmental Monitoring; Flame Retardants; Ibuprofen; Insecticides; Naproxen; Organophosphates; Plasticizers; Salicylic Acid; Seasons; Sewage; Spain; Sunscreening Agents; Triclosan; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Pollution, Chemical | 2012 |
Biofilm controlled sorption of selected acidic drugs on river sediments characterized by different organic carbon content.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biofilms; Carbon; Diclofenac; Gas Chromatography-Mass Spectrometry; Geologic Sediments; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Naproxen; Rivers; Water Pollutants, Chemical | 2012 |
Hydrogen sulfide-releasing NSAIDs inhibit the growth of human cancer cells: a general property and evidence of a tissue type-independent effect.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Aspirin; Cell Line, Tumor; Cell Proliferation; Growth Inhibitors; Humans; Hydrogen Sulfide; Ibuprofen; Naproxen; Sulindac; Thiones | 2012 |
Risk assessment of premature drug release during wet granulation of ordered mesoporous silica loaded with poorly soluble compounds itraconazole, fenofibrate, naproxen, and ibuprofen.
Topics: Calorimetry, Differential Scanning; Carboxymethylcellulose Sodium; Excipients; Fenofibrate; Ibuprofen; Itraconazole; Naproxen; Particle Size; Porosity; Powders; Risk Assessment; Silicon Dioxide; Solubility; Temperature | 2012 |
Determination of non-steroidal anti-inflammatory drugs in water samples by solid-phase microextraction based sol-gel technique using poly(ethylene glycol) grafted multi-walled carbon nanotubes coated fiber.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Gas; Diclofenac; Gels; Hydrogen-Ion Concentration; Ibuprofen; Nanotubes, Carbon; Naproxen; Polyethylene Glycols; Salts; Solid Phase Microextraction; Temperature; Time Factors; Water Pollutants, Chemical | 2012 |
Insight into NSAID-induced membrane alterations, pathogenesis and therapeutics: characterization of interaction of NSAIDs with phosphatidylcholine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line, Tumor; Cell Membrane Permeability; Fluorescent Dyes; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Lipid Bilayers; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Naproxen; Phosphatidylcholines; Pyridinium Compounds; Spectroscopy, Fourier Transform Infrared; Surface Plasmon Resonance | 2012 |
Bioavailability of pharmaceuticals in waters close to wastewater treatment plants: use of fish bile for exposure assessment.
Topics: Animals; Anti-Inflammatory Agents; Bile; Biological Availability; Carbamazepine; Chromatography, Liquid; Citalopram; Cyclohexanols; Diclofenac; Finland; Ibuprofen; Liver; Male; Naproxen; Oncorhynchus mykiss; Plasma; Venlafaxine Hydrochloride; Wastewater; Water Pollutants, Chemical | 2012 |
Rejection of pharmaceuticals by forward osmosis membranes.
Topics: Carbamazepine; Diclofenac; Filtration; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Membranes, Artificial; Naproxen; Osmosis; Pharmaceutical Preparations; Water Pollutants, Chemical; Water Purification | 2012 |
Acidic pharmaceuticals in domestic wastewater and receiving water from hyper-urbanization city of China (Shanghai): environmental release and ecological risk.
Topics: China; Cities; Diclofenac; Environmental Monitoring; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Risk Assessment; Urbanization; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Water Pollution, Chemical | 2013 |
Curcumin binds to Aβ1-40 peptides and fibrils stronger than ibuprofen and naproxen.
Topics: Amyloid; Amyloid beta-Peptides; Binding Sites; Curcumin; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Models, Molecular; Naproxen; Peptide Fragments | 2012 |
Predictability of metabolism of ibuprofen and naproxen using chimeric mice with human hepatocytes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chimera; Cytochrome P-450 Enzyme System; Hepatocytes; Humans; Ibuprofen; Inactivation, Metabolic; Male; Metabolome; Mice; Mice, SCID; Microsomes, Liver; Naproxen; Rats; Rats, Sprague-Dawley | 2012 |
Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3.
Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anti-Inflammatory Agents, Non-Steroidal; Flufenamic Acid; Flurbiprofen; Hydroxyprostaglandin Dehydrogenases; Ibuprofen; Indomethacin; Meclofenamic Acid; Mefenamic Acid; Naproxen; Sulindac; Tolmetin | 2012 |
The role of microbial adaptation and biodegradable dissolved organic carbon on the attenuation of trace organic chemicals during groundwater recharge.
Topics: 2-Methyl-4-chlorophenoxyacetic Acid; 2,4-Dichlorophenoxyacetic Acid; Adaptation, Physiological; Biodegradation, Environmental; Carbon; Clofibric Acid; Gemfibrozil; Groundwater; Ibuprofen; Ketoprofen; Naproxen; Organic Chemicals; Soil Microbiology; Water Microbiology; Water Pollutants, Chemical; Water Purification | 2012 |
Pre-concentration of non-steroidal anti-inflammatory drugs in water using dispersive liquid-liquid and single-drop microextraction with high-performance liquid chromatography.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Diclofenac; Ibuprofen; Liquid Phase Microextraction; Naproxen; Water Pollutants, Chemical | 2012 |
Use of nonsteroidal anti-inflammatory drugs among healthy people and specific cerebrovascular safety.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Brain Ischemia; Cohort Studies; Denmark; Diclofenac; Humans; Ibuprofen; Intracranial Hemorrhages; Naproxen; Odds Ratio; Proportional Hazards Models; Risk; Stroke | 2014 |
Comparative effects of non-steroidal anti-inflammatory drugs (NSAIDs) on blood pressure in patients with hypertension.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure; Celecoxib; Drug Interactions; Female; Humans; Hypertension; Ibuprofen; Indiana; Linear Models; Male; Middle Aged; Naproxen; Odds Ratio; Propensity Score; Pyrazoles; Retrospective Studies; Risk Assessment; Risk Factors; Sulfonamides; Treatment Outcome | 2012 |
Determination of non-steroidal anti-inflammatory drugs in urine by hollow-fiber liquid membrane-protected solid-phase microextraction based on sol-gel fiber coating.
Topics: 1-Octanol; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Gas; Diclofenac; Drug Stability; Humans; Ibuprofen; Limit of Detection; Linear Models; Nanotubes, Carbon; Naproxen; Phase Transition; Porosity; Reproducibility of Results; Sodium Chloride; Solid Phase Microextraction; Temperature | 2012 |
The anti-inflammatory drugs diclofenac, naproxen and ibuprofen are found in the bile of wild fish caught downstream of a wastewater treatment plant.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile; Cyprinidae; Diclofenac; Environmental Monitoring; Female; Ibuprofen; Lakes; Male; Naproxen; Waste Disposal, Fluid; Water Pollutants, Chemical | 2013 |
NMR spectrometry isotopic fingerprinting: a tool for the manufacturer for tracking active pharmaceutical ingredients from starting materials to final medicines.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Carbon Isotopes; Chemistry, Pharmaceutical; Counterfeit Drugs; Deuterium; Fraud; Ibuprofen; Magnetic Resonance Spectroscopy; Naproxen; Principal Component Analysis; Quality Control; Technology, Pharmaceutical | 2013 |
Multi-phase partitioning, ecological risk and fate of acidic pharmaceuticals in a wastewater receiving river: the role of colloids.
Topics: Aquatic Organisms; Clofibric Acid; Colloids; Diclofenac; Ecotoxicology; Geologic Sediments; Ibuprofen; Ketoprofen; Models, Theoretical; Naproxen; Pharmaceutical Preparations; Risk Assessment; Rivers; Wastewater; Water Pollutants, Chemical | 2013 |
A new method for the enhancement of electromembrane extraction efficiency using carbon nanotube reinforced hollow fiber for the determination of acidic drugs in spiked plasma, urine, breast milk and wastewater samples.
Topics: Electrochemical Techniques; Electrophoresis, Capillary; Female; Humans; Hydrogen-Ion Concentration; Ibuprofen; Iran; Limit of Detection; Membranes, Artificial; Milk, Human; Models, Chemical; Nanotubes, Carbon; Naproxen; Pharmaceutical Preparations; Reproducibility of Results; Wastewater; Water Pollutants, Chemical | 2013 |
Effects of ibuprofen, diclofenac, naproxen, and piroxicam on the course of pregnancy and pregnancy outcome: a prospective cohort study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Diclofenac; Female; Humans; Ibuprofen; Infant, Low Birth Weight; Infant, Newborn; Naproxen; Norway; Piroxicam; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Risk; Young Adult | 2013 |
Detection of target proteins by fluorescence anisotropy.
Topics: Biotin; Cyclooxygenase 1; Fluorescence Polarization; Ibuprofen; Kinetics; Ligands; Molecular Structure; Naproxen; Progesterone; Streptavidin; Thermodynamics | 2013 |
Evaluating the fate of six common pharmaceuticals using a reactive transport model: insights from a stream tracer test.
Topics: Adsorption; Bezafibrate; Chromatography, High Pressure Liquid; Clofibric Acid; Ibuprofen; Metoprolol; Models, Theoretical; Naproxen; Pharmaceutical Preparations; Rivers; Sensitivity and Specificity; Sweden; Tandem Mass Spectrometry; Water Movements; Water Pollutants, Chemical | 2013 |
[Occurrence and risk assessment of five selected PPCPs in municipal wastewater treatment plant and the receiving water].
Topics: China; Cities; Clofibric Acid; Diclofenac; Environmental Monitoring; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Risk Assessment; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2013 |
Sensing chiral drugs by using CdSe/ZnS nanoparticles capped with N-acetyl-L-cysteine methyl ester.
Topics: Acetylcysteine; Cadmium Compounds; Circular Dichroism; Esters; Flurbiprofen; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Quantum Dots; Selenium Compounds; Spectrometry, Fluorescence; Stereoisomerism; Sulfides; Zinc Compounds | 2013 |
Non-steroidal anti-inflammatory drugs in Indian rivers.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Humans; Ibuprofen; India; Ketoprofen; Naproxen; Rivers; Sewage; Solid Phase Extraction; Water Pollutants, Chemical | 2014 |
Burrowing as a non-reflex behavioural readout for analgesic action in a rat model of sub-chronic knee joint inflammation.
Topics: Analgesia; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Chronic Disease; Disease Models, Animal; Ibuprofen; Inflammation; Knee Joint; Male; Naproxen; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Reflex | 2014 |
Biodegradable polyesters containing ibuprofen and naproxen as pendant groups.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biocompatible Materials; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Fibroblasts; Ibuprofen; Mice; Molecular Structure; Naproxen; Polyesters; Structure-Activity Relationship | 2013 |
More pain for painkillers.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Humans; Ibuprofen; Naproxen; Pain; Pyrazoles; Risk Factors; Safety-Based Drug Withdrawals; Sulfonamides; United States; United States Food and Drug Administration | 2013 |
Occurrence and removal of selected micropollutants in a water treatment plant.
Topics: 2,4-Dichlorophenoxyacetic Acid; Adsorption; Benzhydryl Compounds; Carbamazepine; Chlorine; Endocrine Disruptors; Environmental Monitoring; Halogenation; Ibuprofen; Naproxen; Phenols; Republic of Korea; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification | 2014 |
Ibuprofen does not seem to increase global malformation risk but NSAID use in late pregnancy remains a concern.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans; Ibuprofen; Naproxen; Piroxicam; Pregnancy; Pregnancy Complications; Pregnancy Outcome | 2014 |
Optimization of naproxen and ibuprofen removal in photolysis using a Box-Behnken design: effect of Fe(III), NO3-, and humic acid.
Topics: Humic Substances; Hydroxyl Radical; Ibuprofen; Iron; Kinetics; Models, Theoretical; Naproxen; Nitrates; Photolysis; Regression Analysis; Ultraviolet Rays; Water Pollutants, Chemical; Water Purification | 2014 |
Fluorophore-labeled cyclooxygenase-2 inhibitors for the imaging of cyclooxygenase-2 overexpression in cancer: synthesis and biological studies.
Topics: 4-Chloro-7-nitrobenzofurazan; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cell Line, Tumor; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Fluorescent Dyes; HCT116 Cells; Humans; Ibuprofen; Microscopy, Confocal; Naproxen; Protein Binding; Pyrazoles; Sulfonamides | 2014 |
High-performance liquid chromatographic enantioseparation of racemic drugs based on homochiral metal-organic framework.
Topics: Benzoin; Benzyl Alcohols; Chromatography, High Pressure Liquid; Coordination Complexes; Ethylenediamines; Ibuprofen; Ketoprofen; Naproxen; Porosity; Pyridines; Stereoisomerism; Zinc | 2014 |
Genotoxic response and oxidative stress induced by diclofenac, ibuprofen and naproxen in Daphnia magna.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biomarkers; Daphnia; Diclofenac; DNA Damage; Ibuprofen; Lipid Peroxidation; Mexico; Mutagenicity Tests; Naproxen; No-Observed-Adverse-Effect Level; Oxidative Stress; Protein Carbonylation; Superoxide Dismutase; Time Factors; Toxicity Tests, Acute; Water Pollutants, Chemical | 2014 |
Determination of naproxen in human plasma by GC-MS.
Topics: Adult; Gas Chromatography-Mass Spectrometry; Healthy Volunteers; Humans; Ibuprofen; Liquid-Liquid Extraction; Naproxen; Sensitivity and Specificity | 2014 |
Non-steroidal anti-inflammatory drugs and cancer risk in women: results from the Women's Health Initiative.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Female; Humans; Ibuprofen; Incidence; Middle Aged; Naproxen; Neoplasms; Postmenopause; Prospective Studies; Risk | 2014 |
Cardiovascular safety of NSAIDs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Ibuprofen; Naproxen | 2014 |
A fast and reliable empirical approach for estimating solubility of crystalline drugs in polymers for hot melt extrusion formulations.
Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallization; Drug Stability; Glass; Hot Temperature; Ibuprofen; Naproxen; Pharmaceutical Preparations; Polyethylene Glycols; Polymers; Polyvinyls; Solubility; Transition Temperature | 2014 |
Anti-inflammatory drugs interacting with Zn (II) metal ion based on thiocyanate and azide ligands: synthesis, spectroscopic studies, DFT calculations and antibacterial assays.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Azides; Escherichia coli; Ibuprofen; Naproxen; Staphylococcus aureus; Thiocyanates; Zinc | 2014 |
Removal of acidic pharmaceuticals within a nitrifying recirculating biofilter.
Topics: Adsorption; Bacteria; Biofilms; Diclofenac; DNA, Bacterial; Filtration; Gemfibrozil; Genes, Bacterial; Ibuprofen; Naproxen; Nitrification; Waste Disposal, Fluid; Water Pollutants, Chemical | 2014 |
Ask the doctor. Is it okay to take both aspirin and ibuprofen therapies?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Contraindications; Drug Interactions; Heart Diseases; Humans; Ibuprofen; Naproxen | 2014 |
Functional adrenal insufficiency complicating an overdose of naproxen and ibuprofen.
Topics: Acidosis; Adolescent; Adrenal Insufficiency; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Dopamine; Dopamine Agents; Drug Overdose; Humans; Hydrocortisone; Hypotension; Ibuprofen; Male; Naproxen; Shock; Suicide, Attempted; Vasoconstrictor Agents | 2015 |
Chromatographycally efficient microspherical composites of molecularly imprinted xerogels deposited inside mesoporous silica.
Topics: Gels; Ibuprofen; Microscopy, Electron, Scanning; Microspheres; Molecular Imprinting; Naproxen; Porosity; Silicon Dioxide | 2014 |
[Simultaneous determination of nine pharmaceuticals personal care products in waters by solid phase extraction-gas chromatography-mass spectrometry].
Topics: Acetaminophen; Agricultural Irrigation; Benzhydryl Compounds; Clofibric Acid; Diclofenac; Gas Chromatography-Mass Spectrometry; Ibuprofen; Ketoprofen; Naproxen; Phenols; Salicylic Acid; Solid Phase Extraction; Triclosan; Water; Water Pollutants, Chemical | 2014 |
Fast ibuprofen, ketoprofen and naproxen simultaneous determination in human serum for clinical toxicology by GC-FID.
Topics: Chromatography, Gas; Humans; Ibuprofen; Ketoprofen; Naproxen | 2014 |
Binary mixtures of diclofenac with paracetamol, ibuprofen, naproxen, and acetylsalicylic acid and these pharmaceuticals in isolated form induce oxidative stress on Hyalella azteca.
Topics: Acetaminophen; Amphipoda; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers; Catalase; Diclofenac; Glutathione Peroxidase; Ibuprofen; Lipid Peroxidation; Naproxen; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Superoxide Dismutase; Water Pollutants, Chemical | 2014 |
Determination of thermodynamic values of acidic dissociation constants and complexation constants of profens and their utilization for optimization of separation conditions by Simul 5 Complex.
Topics: Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Computer Simulation; Electrophoresis, Capillary; Flurbiprofen; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Magnetic Resonance Spectroscopy; Naproxen; Osmolar Concentration; Software; Thermodynamics; Viscosity | 2014 |
Occurrence of selected pharmaceuticals in the principal sewage treatment plants in Rome (Italy) and in the receiving surface waters.
Topics: Carbamazepine; Chromatography, Liquid; Diclofenac; Environmental Monitoring; Estrone; Gemfibrozil; Humans; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Risk Assessment; Rivers; Rome; Seasons; Solid Phase Extraction; Tandem Mass Spectrometry; Waste Disposal, Fluid; Water Pollutants, Chemical | 2015 |
Ion-exchange selectivity of diclofenac, ibuprofen, ketoprofen, and naproxen in ureolyzed human urine.
Topics: Acetaminophen; Anion Exchange Resins; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Diclofenac; Humans; Hydrogen Bonding; Ibuprofen; Ion Exchange; Ketoprofen; Kinetics; Molecular Structure; Naproxen; Static Electricity; Urea; Waste Disposal, Fluid; Water Pollutants, Chemical | 2015 |
Distinct enantiomeric signals of ibuprofen and naproxen in treated wastewater and sewer overflow.
Topics: Ibuprofen; Naproxen; Sewage; Stereoisomerism; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2014 |
Marginally designed new profen analogues have the potential to inhibit cyclooxygenase enzymes.
Topics: Arachidonate 5-Lipoxygenase; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Design; Flurbiprofen; Ibuprofen; Lipoxygenase Inhibitors; Molecular Structure; Naproxen; Propionates; Structure-Activity Relationship | 2015 |
Enantioselective determination of representative profens in wastewater by a single-step sample treatment and chiral liquid chromatography-tandem mass spectrometry.
Topics: Chromatography, Liquid; Ibuprofen; Ketoprofen; Limit of Detection; Naproxen; Stereoisomerism; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical | 2015 |
Sensing of enantiomeric excess in chiral carboxylic acids.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Carboxylic Acids; Crystallography, X-Ray; Fluorescence; Fluorescent Dyes; Ibuprofen; Ketoprofen; Models, Molecular; Molecular Structure; Naproxen; Stereoisomerism | 2015 |
[[Chiral separation of five arylpropionic acid drugs and determination of their enantiomers in pharmaceutical preparations by reversed-phase high performance liquid chromatography with cellulose-tris-(4-methylbenzoate) stationary phase]].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Benzopyrans; Cellulose; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Flurbiprofen; Ibuprofen; Naproxen; Phenylpropionates; Propionates; Stereoisomerism | 2014 |
Dendrimer-functionalized mesoporous silica as a reversed-phase/anion-exchange mixed-mode sorbent for solid phase extraction of acid drugs in human urine.
Topics: Adsorption; Chromatography, High Pressure Liquid; Dendrimers; Female; Humans; Ibuprofen; Ion Exchange; Ketoprofen; Naproxen; Pharmaceutical Preparations; Porosity; Silicon Dioxide; Solid Phase Extraction; Solvents; Spectroscopy, Fourier Transform Infrared | 2015 |
NSAIDs and spontaneous abortions - true effect or an indication bias?
Topics: Abortion, Spontaneous; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans; Ibuprofen; Indomethacin; Israel; Middle Aged; Naproxen; Pregnancy; Retrospective Studies; Time Factors; Young Adult | 2015 |
Effects of over-the-counter analgesic use on reproductive hormones and ovulation in healthy, premenopausal women.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anovulation; Aspirin; Female; Follicular Phase; Follow-Up Studies; Humans; Ibuprofen; Naproxen; New York; Ovulation; Premenopause; Progesterone; Young Adult | 2015 |
Cyclosporin A-sensitive cytotoxicity of flurbiprofen non-stereoselectively mediated by cytochrome P450 metabolism in three-dimensional cultured rat hepatocytes.
Topics: Adenosine Triphosphate; Animals; Chemical and Drug Induced Liver Injury; Cyclosporine; Cytochrome P-450 Enzyme System; Flurbiprofen; Hepatocytes; Ibuprofen; L-Lactate Dehydrogenase; Male; Mitochondria; Naproxen; Phenylpropionates; Rats; Rats, Wistar; Stereoisomerism | 2015 |
Prevalence, trends, patterns and associations of analgesic use in Germany.
Topics: Acetaminophen; Adolescent; Adult; Age Factors; Aged; Analgesics; Aspirin; Diclofenac; Drug Therapy; Female; Germany; Health Surveys; Humans; Ibuprofen; Logistic Models; Male; Middle Aged; Multivariate Analysis; Naproxen; Nonprescription Drugs; Pain; Prevalence; Sex Factors; Social Class; Young Adult | 2015 |
Validated HPLC-UV method for determination of naproxen in human plasma with proven selectivity against ibuprofen and paracetamol.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Humans; Ibuprofen; Naproxen; Spectrophotometry, Ultraviolet | 2016 |
Study of Binding Properties Between Two New Ibuprofen and Naproxen Based Acyl Hydrazone Derivatives and Trypsin.
Topics: Binding Sites; Hydrazones; Ibuprofen; Molecular Structure; Naproxen; Spectrometry, Fluorescence; Thermodynamics; Trypsin | 2016 |
Cost-effectiveness of nonsteroidal anti-inflammatory drugs and opioids in the treatment of knee osteoarthritis in older patients with multiple comorbidities.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Comorbidity; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Female; Health Services Research; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Nonprescription Drugs; Osteoarthritis, Knee; Pain; Pain Measurement; Proton Pump Inhibitors; Quality-Adjusted Life Years; Sensitivity and Specificity; Tramadol; Treatment Outcome; United States | 2016 |
Single-drop microextraction combined in-line with capillary electrophoresis for the determination of nonsteroidal anti-inflammatory drugs in urine samples.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Electrophoresis, Capillary; Equipment Design; Humans; Ibuprofen; Ketoprofen; Limit of Detection; Liquid Phase Microextraction; Naproxen; Urinalysis | 2016 |
Occurrence of non-steroidal anti-inflammatory drugs in Tehran source water, municipal and hospital wastewaters, and their ecotoxicological risk assessment.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Liquid; Diclofenac; Ecotoxicology; Environmental Monitoring; Hospitals; Ibuprofen; Iran; Mass Spectrometry; Naproxen; Risk Assessment; Rivers; Solid Phase Extraction; Wastewater; Water Pollutants, Chemical | 2015 |
Graphene oxide-based dispersive solid-phase extraction combined with in situ derivatization and gas chromatography-mass spectrometry for the determination of acidic pharmaceuticals in water.
Topics: Diclofenac; Gas Chromatography-Mass Spectrometry; Graphite; Ibuprofen; Ketoprofen; Naproxen; Osmolar Concentration; Pharmaceutical Preparations; Solid Phase Extraction; Solvents; Water; Water Pollutants, Chemical | 2015 |
The Influence of Efflux Pump Inhibitors on the Activity of Non-Antibiotic NSAIDS against Gram-Negative Rods.
Topics: Acetaminophen; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Escherichia coli; Gram-Negative Bacteria; Ibuprofen; Mefenamic Acid; Microbial Sensitivity Tests; Naproxen | 2016 |
Acylated-naproxen as the surface-active template in the preparation of micro- and nanospherical imprinted xerogels by emulsion techniques.
Topics: Acylation; Chemistry Techniques, Analytical; Emulsions; Gels; Ibuprofen; Microspheres; Molecular Imprinting; Nanospheres; Naproxen; Surface-Active Agents | 2016 |
Indomethacin inhibits tetrodotoxin-resistant Na(+) channels at acidic pH in rat nociceptive neurons.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Female; Hydrogen-Ion Concentration; Ibuprofen; Indomethacin; Kinetics; Male; Membrane Potentials; Naproxen; Nociceptors; Patch-Clamp Techniques; Rats, Sprague-Dawley; Sodium Channels; Trigeminal Ganglion | 2016 |
NSAIDs and serious cardiovascular disorders: especially cox-2 inhibitors and diclofenac.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Ibuprofen; Naproxen | 2016 |
Use of non-steroidal anti-inflammatory drugs correlates with the risk of venous thromboembolism in knee osteoarthritis patients: a UK population-based case-control study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Humans; Ibuprofen; Lactones; Logistic Models; Male; Meloxicam; Middle Aged; Naproxen; Odds Ratio; Osteoarthritis, Knee; Risk Factors; Sulfones; Thiazines; Thiazoles; Treatment Outcome; United Kingdom; Venous Thromboembolism | 2016 |
Common pain relievers may increase heart problems. High-dosage ibuprofen and diclofenac linked to elevated risk of death; naproxen, acetaminophen offer alternatives.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Ibuprofen; Naproxen; Pain | 2010 |
Ultrasound-assisted magnetic dispersive solid-phase microextraction: A novel approach for the rapid and efficient microextraction of naproxen and ibuprofen employing experimental design with high-performance liquid chromatography.
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Equipment Design; Humans; Ibuprofen; Magnetics; Naproxen; Solid Phase Microextraction; Ultrasonics; Water Pollutants, Chemical | 2016 |
Hybrid Compounds Strategy in the Synthesis of Oleanolic Acid Skeleton-NSAID Derivatives.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Ibuprofen; Inflammation; Ketoprofen; Molecular Structure; Naproxen; Oleanolic Acid | 2016 |
Suitability of passive sampling for the monitoring of pharmaceuticals in Finnish surface waters.
Topics: Calibration; Carbamazepine; Chromatography, Liquid; Diclofenac; Environmental Monitoring; Finland; Ibuprofen; Ketoprofen; Lakes; Naproxen; Pharmaceutical Preparations; Rivers; Seasons; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical | 2016 |
Sorption, photodegradation, and chemical transformation of naproxen and ibuprofen in soils and water.
Topics: Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Environmental Monitoring; Ibuprofen; Naproxen; Photolysis; Soil Pollutants; South Carolina; Water Pollutants, Chemical | 2016 |
Determination of ibuprofen, naproxen and diclofenac in aqueous samples using a multi-template molecularly imprinted polymer as selective adsorbent for solid-phase extraction.
Topics: Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Diclofenac; Drug Residues; Ibuprofen; Indicators and Reagents; Molecular Imprinting; Naproxen; Pharmaceutical Solutions; Polymers; Reproducibility of Results; Rivers; Solid Phase Extraction; Wastewater; Water Pollutants, Chemical | 2016 |
Biophysical study of the non-steroidal anti-inflammatory drugs (NSAID) ibuprofen, naproxen and diclofenac with phosphatidylserine bilayer membranes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Lipid Bilayers; Naproxen; Phosphatidylserines | 2016 |
Hyperbranched polyglycerol/graphene oxide nanocomposite reinforced hollow fiber solid/liquid phase microextraction for measurement of ibuprofen and naproxen in hair and waste water samples.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Glycerol; Graphite; Hair; Humans; Ibuprofen; Limit of Detection; Liquid Phase Microextraction; Nanocomposites; Naproxen; Oxides; Polymers; Solid Phase Microextraction; Wastewater; Water Pollutants | 2016 |
Enantioselective simultaneous analysis of selected pharmaceuticals in environmental samples by ultrahigh performance supercritical fluid based chromatography tandem mass spectrometry.
Topics: Aminorex; Carbazoles; Chloramphenicol; Chromatography, High Pressure Liquid; Chromatography, Supercritical Fluid; Flurbiprofen; Humans; Ibuprofen; Ifosfamide; Imidazoles; Indoprofen; Molecular Structure; Naproxen; Ofloxacin; Omeprazole; Praziquantel; Solid Phase Extraction; Stereoisomerism; Tandem Mass Spectrometry; Tetramisole; Water Pollutants, Chemical | 2016 |
Unusual anti-leukemia activity of nanoformulated naproxen and other non-steroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Chemical Precipitation; Chemistry, Pharmaceutical; Drug Liberation; Humans; Ibuprofen; Leukemia; Nanoparticles; Naproxen; Particle Size; Solubility; Spectroscopy, Fourier Transform Infrared; Temperature; X-Ray Diffraction | 2016 |
The fate of selected pharmaceuticals in solar stills: Transfer, thermal degradation or photolysis?
Topics: Ampicillin; Carbamazepine; Diclofenac; Drug Residues; Ibuprofen; Naproxen; Photolysis; Sunlight; Water Pollutants, Chemical | 2017 |
Adsorptive Removal of Pharmaceuticals and Personal Care Products from Water with Functionalized Metal-organic Frameworks: Remarkable Adsorbents with Hydrogen-bonding Abilities.
Topics: Adsorption; Benzophenones; Humans; Hydrogen Bonding; Ibuprofen; Naproxen; Wastewater; Water Purification | 2016 |
Central nervous system toxicity of mefenamic acid overdose compared with other NSAIDs: an analysis of cases reported to the United Kingdom National Poisons Information Service.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Diclofenac; Dose-Response Relationship, Drug; Drug Overdose; Female; Humans; Ibuprofen; Infant; Infant, Newborn; Logistic Models; Male; Mefenamic Acid; Middle Aged; Multivariate Analysis; Naproxen; Neurotoxicity Syndromes; Poison Control Centers; Sex Factors; United Kingdom; Young Adult | 2017 |
Preconception use of pain-relievers and time-to-pregnancy: a prospective cohort study.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Opioid; Aspirin; Female; Humans; Ibuprofen; Internet; Naproxen; Pain; Pregnancy; Prospective Studies; Time-to-Pregnancy | 2017 |
Minimizing pain medication use and its associated costs following robotic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Drug Costs; Electronic Health Records; Endometrial Neoplasms; Female; Humans; Ibuprofen; Middle Aged; Minimally Invasive Surgical Procedures; Morphine; Naproxen; Pain, Postoperative; Retrospective Studies; Robotic Surgical Procedures | 2017 |
Calculated Resonance Vibrational Raman Optical Activity Spectra of Naproxen and Ibuprofen.
Topics: Ibuprofen; Naproxen; Quantum Theory; Spectrum Analysis, Raman; Vibration | 2016 |
Poly(aryleneethynylene) Tongue That Identifies Nonsteroidal Anti-Inflammatory Drugs in Water: A Test Case for Combating Counterfeit Drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Counterfeit Drugs; Diclofenac; Ibuprofen; Naproxen; Water | 2017 |
Non-steroidal anti-inflammatory drugs in the watercourses of Elbe basin in Czech Republic.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Czech Republic; Diclofenac; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Rivers; Water Pollutants, Chemical | 2017 |
Inflammation: NSAIDs and cardiovascular risk in arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cardiovascular Diseases; Celecoxib; Humans; Ibuprofen; Inflammation; Naproxen; Risk Factors | 2017 |
Rates of Nonsteroidal Anti-Inflammatory Drug Use in Patients with Established Cardiovascular Disease: A Retrospective, Cross-Sectional Study from NHANES 2009-2010.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cross-Sectional Studies; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Nutrition Surveys; Prescription Drugs; Retrospective Studies | 2017 |
Hydrophobin-nanofibrillated cellulose stabilized emulsions for encapsulation and release of BCS class II drugs.
Topics: Cellulose; Delayed-Action Preparations; Drug Liberation; Emulsions; Fungal Proteins; Ibuprofen; Nanofibers; Naproxen; Oleic Acids; Soybean Oil; Trichoderma; Viscosity | 2017 |
Therapy: Cardiovascular safety of celecoxib, naproxen and ibuprofen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular System; Celecoxib; Clinical Trials as Topic; Cyclooxygenase 2 Inhibitors; Humans; Ibuprofen; Naproxen; Osteoarthritis; Outcome Assessment, Health Care; Safety | 2017 |
Mass spectrometry based in vitro assay investigations on the transformation of pharmaceutical compounds by oxidative enzymes.
Topics: Acetaminophen; Carbamazepine; Diclofenac; Horseradish Peroxidase; Ibuprofen; Laccase; Mass Spectrometry; Naproxen; Oxidation-Reduction; Sotalol; Sulfamethoxazole; Water Pollutants, Chemical; Water Purification | 2017 |
Sorption and desorption of selected non-steroidal anti-inflammatory drugs in an agricultural loam-textured soil.
Topics: Adsorption; Agriculture; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Ketoprofen; Naproxen; Soil; Soil Pollutants | 2017 |
Evaluation of
Topics: Aminosalicylic Acid; Anti-Inflammatory Agents, Non-Steroidal; Antitubercular Agents; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Cimetidine; Drug Interactions; HEK293 Cells; Humans; Ibuprofen; Liver-Specific Organic Anion Transporter 1; Naproxen; Octamer Transcription Factor-1; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organic Cation Transporter 2; Probenecid; Proton Pump Inhibitors; Quinidine; Rifampin; Verapamil | 2017 |
Transport behavior of the pharmaceutical compounds carbamazepine, sulfamethoxazole, gemfibrozil, ibuprofen, and naproxen, and the lifestyle drug caffeine, in saturated laboratory columns.
Topics: Caffeine; Carbamazepine; Filtration; Gemfibrozil; Ibuprofen; Naproxen; Ontario; Silicon Dioxide; Sulfamethoxazole; Water Pollutants, Chemical | 2017 |
Cardiovascular Safety of Celecoxib, Naproxen, or Ibuprofen for Arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Celecoxib; Humans; Ibuprofen; Naproxen; Pyrazoles; Sulfonamides | 2017 |
Cardiovascular Safety of Celecoxib, Naproxen, or Ibuprofen for Arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Celecoxib; Humans; Ibuprofen; Naproxen; Pyrazoles; Sulfonamides | 2017 |
NSAIDs for high-risk patients: none, celecoxib, or naproxen?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Humans; Ibuprofen; Naproxen; Pyrazoles; Sulfonamides | 2017 |
Inclusion Complexes of a New Family of Non-Ionic Amphiphilic Dendrocalix[4]arene and Poorly Water-Soluble Drugs Naproxen and Ibuprofen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Calixarenes; Drug Carriers; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Models, Molecular; Naproxen; Solubility; Surface-Active Agents; Water | 2017 |
Direct Conjugation of Emerging Contaminants in Arabidopsis: Indication for an Overlooked Risk in Plants?
Topics: Animals; Arabidopsis; Humans; Ibuprofen; Naproxen; Soil; Wastewater; Water Pollutants, Chemical | 2017 |
[Cardiovascular safety of celecoxib : Prospective Randomized Evaluation of Celecoxib Integrated Safety versus Ibuprofen or Naproxen (PRECISION)].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Double-Blind Method; Humans; Ibuprofen; Naproxen; Prospective Studies; Pyrazoles; Sulfonamides | 2017 |
Evaluation of anti-inflammatory and ulcerogenic potential of zinc-ibuprofen and zinc-naproxen complexes in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; Carrageenan; Edema; Gastric Mucosa; Ibuprofen; Inflammation; Male; Naproxen; Organometallic Compounds; Rats; Rats, Wistar; Zinc; Zinc Compounds | 2017 |
Non-inferiority versus superiority drug claims: the (not so) subtle distinction.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Celecoxib; Cyclooxygenase 2 Inhibitors; Data Interpretation, Statistical; Drug Approval; Drug Therapy; Equivalence Trials as Topic; Humans; Ibuprofen; Models, Statistical; Naproxen; Research Design; Risk Assessment; Risk Factors; Treatment Outcome | 2017 |
Occurrence of naproxen, ibuprofen, and diclofenac residues in wastewater and river water of KwaZulu-Natal Province in South Africa.
Topics: Chromatography, High Pressure Liquid; Cities; Diclofenac; Dose-Response Relationship, Drug; Environmental Monitoring; Ibuprofen; Naproxen; Rivers; Solid Phase Extraction; South Africa; Wastewater; Water Pollutants, Chemical | 2017 |
Controlled-release nanoencapsulating microcapsules to combat inflammatory diseases.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Capsules; Celecoxib; Cimetidine; Delayed-Action Preparations; Diffusion; Drug Combinations; Drug Compounding; Drug Liberation; Drug Stability; Gastric Juice; Histamine H2 Antagonists; Ibuprofen; Inflammation; Kinetics; Models, Chemical; Nanocapsules; Nanotechnology; Naproxen; Polymers; Solubility; Technology, Pharmaceutical | 2017 |
Use of multicriteria decision analysis for assessing the benefit and risk of over-the-counter analgesics.
Topics: Analgesics; Aspirin; Decision Support Techniques; Gastrointestinal Diseases; Humans; Ibuprofen; Naproxen; Nonprescription Drugs; Pain; Risk Assessment | 2017 |
NSAIDs relieve osteoarthritis (OA) pain, but cardiovascular safety in question even for diclofenac, ibuprofen, naproxen, and celecoxib: what are the alternatives?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Diclofenac; Humans; Ibuprofen; Naproxen; Network Meta-Analysis; Osteoarthritis; Pain | 2017 |
NSAIDs and cardiac arrest: Non-steroidal anti-inflammatory drug use is associated with increased risk of Out-of-hospital Cardiac Arrest: A nationwide Case-Time-Control study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Celecoxib; Denmark; Humans; Ibuprofen; Lactones; Naproxen; Out-of-Hospital Cardiac Arrest; Risk Factors; Sulfones | 2017 |
Levetiracetam+nonsteroidal anti-inflammatory drug binary systems: A contribution to the development of new solid dosage forms.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Drug Combinations; Drug Liberation; Flurbiprofen; Ibuprofen; Ketoprofen; Levetiracetam; Naproxen; Piracetam; Stereoisomerism | 2017 |
Preparation of a reversed-phase/anion-exchange mixed-mode spherical sorbent by Pickering emulsion polymerization for highly selective solid-phase extraction of acidic pharmaceuticals from wastewater.
Topics: Butylene Glycols; Emulsions; Environmental Monitoring; Ibuprofen; Ketoprofen; Limit of Detection; Naproxen; Pharmaceutical Preparations; Polymerization; Reproducibility of Results; Solid Phase Extraction; Wastewater; Water Pollutants, Chemical | 2017 |
Continuous transformation of chiral pharmaceuticals in enzymatic membrane bioreactors for advanced wastewater treatment.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bioreactors; Biotransformation; Ibuprofen; Ketoprofen; Membranes, Artificial; Naproxen; Wastewater; Water Pollutants, Chemical | 2017 |
Safety of non-steroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Celecoxib; Humans; Ibuprofen; Naproxen; Prospective Studies | 2017 |
Multifunctionalized mesoporous silica as an efficient reversed-phase/anion exchange mixed-mode sorbent for solid-phase extraction of four acidic nonsteroidal anti-inflammatory drugs in environmental water samples.
Topics: Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Environmental Monitoring; Fresh Water; Ibuprofen; Ketoprofen; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Naproxen; Silanes; Silicon Dioxide; Solid Phase Extraction; Spectroscopy, Fourier Transform Infrared; Wastewater; Water Pollutants, Chemical | 2017 |
Penetration and pharmacokinetics of non-steroidal anti-inflammatory drugs in rat prostate tissue.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Celecoxib; Chromatography, Liquid; Comparative Effectiveness Research; Diclofenac; Disease Models, Animal; Ibuprofen; Inflammation; Male; Naproxen; Pelvic Pain; Prostate; Prostatitis; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2018 |
Correlation between glucuronidation and covalent adducts formation with proteins of nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Flurbiprofen; Glucuronides; Ibuprofen; Ketoprofen; Male; Microsomes, Liver; Naproxen; Propionates; Protein Binding; Rats, Wistar | 2018 |
Pain Treatment Practices of Community-Dwelling Black Older Adults.
Topics: Aged; Anthropology, Cultural; Black or African American; Codeine; Exercise Therapy; Faith Healing; Female; Healthcare Disparities; Housing for the Elderly; Humans; Hydrocodone; Ibuprofen; Male; Medicine, Traditional; Middle Aged; Naproxen; Pain; Pain Management; Pain Measurement; Psychometrics; Qualitative Research; Surveys and Questionnaires; Tramadol | 2018 |
Use of Polymer Inclusion Membranes (PIMs) as support for electromembrane extraction of non-steroidal anti-inflammatory drugs and highly polar acidic drugs.
Topics: Amoxicillin; Anti-Inflammatory Agents, Non-Steroidal; Cellulose; Electrochemical Techniques; Hippurates; Ibuprofen; Ketoprofen; Membranes, Artificial; Naproxen; Niacin; ortho-Aminobenzoates; Quaternary Ammonium Compounds; Salicylic Acid | 2018 |
Degradation of anti-inflammatory drugs in municipal wastewater by heterogeneous photocatalysis and electro-Fenton process.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Hydrogen Peroxide; Ibuprofen; Naproxen; Wastewater; Water Pollutants, Chemical | 2019 |
Comparative cardiovascular safety of nonsteroidal anti-inflammatory drugs in patients with hypertension: a population-based cohort study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular System; Celecoxib; Cyclooxygenase 2 Inhibitors; Databases, Pharmaceutical; Diclofenac; Female; Hospitalization; Humans; Hypertension; Ibuprofen; Male; Mefenamic Acid; Middle Aged; Naproxen; Risk Factors | 2018 |
Synthesis and antinociceptive evaluation of bioisosteres and hybrids of naproxen, ibuprofen and paracetamol.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Female; Ibuprofen; Imaging, Three-Dimensional; Molecular Docking Simulation; Naproxen; Pain Measurement; Rats; Rats, Wistar | 2018 |
Acute pancreatitis with long-term celecoxib vs. ibuprofen or naproxen: data from the PRECISION trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Celecoxib; Humans; Ibuprofen; Naproxen; Pancreatitis; Risk; Taiwan | 2018 |
The Aspirin-NSAID Interaction: More Data, But a Lack of Clarity Remains.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Ibuprofen; Naproxen | 2018 |
Comparative study of substituted poly(4-vinylbenzyl chloride/ethylene glycol dimethacrylate) sorbents for enrichment of selected pharmaceuticals and estrogens from aqueous samples.
Topics: Adsorption; Antipyrine; Carbamazepine; Estradiol; Estriol; Estrogens; Estrone; Ibuprofen; Methacrylates; Naproxen; Polyethylene Glycols; Polymerization; Polyvinyls; Water Pollutants, Chemical; Water Purification | 2018 |
Transformation, CO
Topics: 2-Methyl-4-chlorophenoxyacetic Acid; Biofilms; Carbon Dioxide; Deltaproteobacteria; Diclofenac; Firmicutes; Gammaproteobacteria; Ibuprofen; In Situ Hybridization, Fluorescence; Naproxen; RNA, Ribosomal, 16S; Waste Disposal, Fluid; Wastewater; Water Microbiology; Water Pollutants, Chemical | 2018 |
Editorial: gastrointestinal safety of COX-2 selective and nonselective NSAIDs-the impact of the PRECISION trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Humans; Ibuprofen; Naproxen | 2018 |
Editorial: gastrointestinal safety of COX-2 selective and nonselective NSAIDs-the impact of the PRECISION trial. Authors' reply.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Humans; Ibuprofen; Naproxen | 2018 |
Preparation, Characterization, and Formulation Development of Drug-Drug Protic Ionic Liquids of Diphenhydramine with Ibuprofen and Naproxen.
Topics: Diphenhydramine; Drug Carriers; Ibuprofen; Ionic Liquids; Magnetic Resonance Spectroscopy; Naproxen | 2018 |
Solid-phase extraction of drugs with cuttlefish bone powder as a sorbent.
Topics: Adsorption; Animals; Bone and Bones; Carbamazepine; Decapodiformes; Ibuprofen; Molecular Structure; Naproxen; Particle Size; Powders; Solid Phase Extraction; Surface Properties | 2018 |
Diclofenac use and cardiovascular risks: series of nationwide cohort studies.
Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cohort Studies; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Humans; Ibuprofen; Male; Middle Aged; Naproxen; Propensity Score; Risk Factors | 2018 |
Comparative study of the toxicity between three non-steroidal anti-inflammatory drugs and their UV/Na
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carps; Diclofenac; Ecological Parameter Monitoring; Environmental Pollutants; Environmental Pollution; Fish Diseases; Ibuprofen; Medical Waste Disposal; Naproxen; Oxidation-Reduction; Photolysis; Sodium Compounds; Sulfates; Toxicity Tests, Acute; Ultraviolet Rays; Wastewater; Water Purification | 2018 |
Conformational study of the electronic interactions and nitric oxide release potential of new S‑nitrosothiols esters derivatives of ibuprofen, naproxen and phenyl acids substituted (SNO-ESTERS): Synthesis, infrared spectroscopy analysis and theoretical ca
Topics: Electrons; Esterification; Ibuprofen; Models, Molecular; Molecular Conformation; Naproxen; Nitric Oxide Donors; Quantum Theory; S-Nitrosothiols; Spectrophotometry, Infrared; Static Electricity | 2019 |
Experimental and theoretical investigations of cyclometalated ruthenium(ii) complex containing CCC-pincer and anti-inflammatory drugs as ligands: synthesis, characterization, inhibition of cyclooxygenase and in vitro cytotoxicity activities in various can
Topics: Adamantane; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Coordination Complexes; Cyclooxygenase Inhibitors; Drug Stability; HEK293 Cells; Humans; Ibuprofen; Ligands; MCF-7 Cells; Molecular Docking Simulation; Molecular Structure; Naproxen; Organophosphorus Compounds; Reactive Oxygen Species; Ruthenium | 2019 |
C18-Coated Solid-Phase Microextraction Fibers for the Quantification of Partitioning of Organic Acids to Proteins, Lipids, and Cells.
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Cattle; Cells, Cultured; Diclofenac; Genistein; HEK293 Cells; Humans; Ibuprofen; Kinetics; Liposomes; Naproxen; Phospholipids; Serum Albumin, Bovine; Solid Phase Microextraction; Torsemide; Warfarin | 2019 |
Photocatalytic degradation of pharmaceutical micro-pollutants using ZnO.
Topics: Catalysis; Environmental Pollutants; Equipment Design; Ibuprofen; Kinetics; Naproxen; Pharmaceutical Preparations; Photochemical Processes; Photolysis; Progesterone; Ultraviolet Rays; Waste Management; Zinc Oxide | 2019 |
Syntheses and cytotoxicity of phosphatidylcholines containing ibuprofen or naproxen moieties.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caco-2 Cells; Cell Line; Cytotoxins; Epithelial Cells; Humans; Ibuprofen; Lysophosphatidylcholines; Naproxen; Palmitic Acid; Phosphatidylcholines; Phospholipids; Swine | 2019 |
Simultaneous enantiomeric analysis of non-steroidal anti-inflammatory drugs in environment by chiral LC-MS/MS: A pilot study in Beijing, China.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Beijing; Chromatography, High Pressure Liquid; Environmental Monitoring; Flurbiprofen; Ibuprofen; Naproxen; Pilot Projects; Rivers; Stereoisomerism; Tandem Mass Spectrometry; Water Pollutants, Chemical | 2019 |
Chitosan tailor-made membranes as biopolymeric support for electromembrane extraction.
Topics: Amoxicillin; Biopolymers; Chitosan; Electrochemical Techniques; Hippurates; Humans; Ibuprofen; Ketoprofen; Naproxen; Niacin; ortho-Aminobenzoates; Salicylic Acid | 2019 |
Nickel-iron layered double hydroxide nanostructures for micro solid phase extraction of nonsteroidal anti-inflammatory drugs, followed by quantitation by HPLC-UV.
Topics: Adsorption; Alloys; Anti-Inflammatory Agents, Non-Steroidal; Biosensing Techniques; Chromatography, High Pressure Liquid; Diclofenac; Humans; Hydroxides; Ibuprofen; Iron; Limit of Detection; Mefenamic Acid; Metal Nanoparticles; Naproxen; Nickel; Reproducibility of Results; Solid Phase Microextraction; Surface Properties | 2019 |
NSAID choice: lessons from PRECISION.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Celecoxib; Humans; Ibuprofen; Naproxen; Pain; Treatment Outcome | 2019 |
Evaluation of the photosynthetic parameters, emission of volatile organic compounds and ultrastructure of common green leafy vegetables after exposure to non-steroidal anti-inflammatory drugs (NSAIDs).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Atriplex; Diclofenac; Environmental Pollutants; Ibuprofen; Lactuca; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Naproxen; Photosynthesis; Plant Leaves; Spinacia oleracea; Volatile Organic Compounds | 2019 |
Oxyfunctionalization of nonsteroidal anti-inflammatory drugs by filamentous-fungi.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Basidiomycota; Cytochrome P-450 Enzyme System; Diclofenac; Fungi; Ibuprofen; Mefenamic Acid; Mucor; Naproxen; Proteomics | 2019 |
Bioremoval of non-steroidal anti-inflammatory drugs by Pseudoxanthomonas sp. DIN-3 isolated from biological activated carbon process.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Charcoal; Diclofenac; Ecosystem; Ibuprofen; Naproxen | 2019 |
A nanohybrid composed of polyoxotungstate and graphene oxide for dispersive micro solid-phase extraction of non-steroidal anti-inflammatory drugs prior to their quantitation by HPLC.
Topics: Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Diclofenac; Graphite; Ibuprofen; Limit of Detection; Nanostructures; Naproxen; Polymers; Porosity; Solid Phase Extraction; Spectrophotometry, Ultraviolet; Tungsten Compounds; Water Pollutants, Chemical | 2019 |
Biological removal of pharmaceuticals by Navicula sp. and biotransformation of bezafibrate.
Topics: Atenolol; Bezafibrate; Biodegradation, Environmental; Carbamazepine; Diatoms; Fresh Water; Ibuprofen; Inactivation, Metabolic; Naproxen; Pharmaceutical Preparations; Sulfamethoxazole; Water Pollutants, Chemical | 2020 |
Monitoring the release of anti-inflammatory and analgesic pharmaceuticals in the receiving environment.
Topics: Analgesics; Anti-Inflammatory Agents; Diclofenac; Environmental Monitoring; Hospitals; Humans; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Seasons; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2019 |
An exploratory study of enantioselective behavior of Sol-Gel encapsulated human serum albumin using frontal analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Naproxen; Phase Transition; Serum Albumin, Human; Stereoisomerism | 2019 |
Evaluation of the binding properties of drugs to albumin from DSC thermograms.
Topics: Calorimetry, Differential Scanning; Ibuprofen; Isoniazid; Naproxen; Protein Binding; Serum Albumin, Bovine; Warfarin | 2020 |
Ecotoxicity screening evaluation of selected pharmaceuticals and their transformation products towards various organisms.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Araceae; Ecotoxicology; Ibuprofen; Naproxen; Water Pollutants, Chemical | 2020 |
Solubility of Pharmaceutical Ingredients in Natural Edible Oils.
Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cinnarizine; Coconut Oil; Drug Compounding; Drug Delivery Systems; Excipients; Felodipine; Fenofibrate; Griseofulvin; Ibuprofen; Indomethacin; Models, Molecular; Naproxen; Plant Oils; Solubility; Soybean Oil; Spectrum Analysis, Raman; Thermodynamics; Transition Temperature; Triglycerides | 2020 |
Diet quality and NSAIDs promote changes in formation of prostaglandins by an aquatic invertebrate.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Diclofenac; Diet; Ibuprofen; Invertebrates; Ketoprofen; Lipid Metabolism; Naproxen; Prostaglandins | 2020 |
Association Between Male Use of Pain Medication and Fecundability.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Birth Rate; Cohort Studies; Female; Fertility; Humans; Ibuprofen; Infertility, Male; Male; Naproxen; Pain; Pregnancy; Surveys and Questionnaires | 2020 |
The design and development of high drug loading amorphous solid dispersion for hot-melt extrusion platform.
Topics: Chemistry, Pharmaceutical; Drug Carriers; Drug Stability; Drug Storage; Excipients; Humidity; Ibuprofen; Indomethacin; Naproxen; Polymers; Polymethacrylic Acids; Solubility; Thermodynamics | 2020 |
Differential actions of indomethacin: clinical relevance in headache.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Headache; Humans; Ibuprofen; Indomethacin; Naproxen | 2021 |
Ibuprofen, a Nonsteroidal Anti-Inflammatory Drug, is a Potent Inhibitor of the Human Sweet Taste Receptor.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzene Derivatives; Cell Line; Dose-Response Relationship, Drug; Humans; Ibuprofen; Molecular Docking Simulation; Molecular Structure; Naproxen; Receptors, G-Protein-Coupled | 2020 |
A Molecularly Imprinted Polymer-based Dye Displacement Assay for the Rapid Visual Detection of Amphetamine in Urine.
Topics: Amphetamine; Amphetamines; Brompheniramine; Bupropion; Coloring Agents; Dose-Response Relationship, Drug; Electrochemical Techniques; False Positive Reactions; Humans; Ibuprofen; Limit of Detection; Molecular Imprinting; Molecularly Imprinted Polymers; Naproxen; Pheniramine; Piperidines; Polymers; Powders; Quetiapine Fumarate; Substance Abuse Detection; Urine | 2020 |
Removal of non-steroidal anti-inflammatory drugs from water by zeolite-rich composites: The interference of inorganic anions on the ibuprofen and naproxen adsorption.
Topics: Adsorption; Hydrogen-Ion Concentration; Ibuprofen; Kinetics; Missouri; Naproxen; Pharmaceutical Preparations; Water; Water Pollutants, Chemical; Zeolites | 2021 |
Fixed Drug Eruption After Ingestion of Naproxen in a Patient Who Tolerated Ibuprofen and Dexketoprofen.
Topics: Administration, Oral; Adult; Allergens; Anti-Inflammatory Agents, Non-Steroidal; Drug Eruptions; Female; Humans; Ibuprofen; Immunization; Ketoprofen; Naproxen; Tromethamine | 2021 |
Cholinium-based ionic liquids as bioinspired hydrotropes to tackle solubility challenges in drug formulation.
Topics: Chemistry, Pharmaceutical; Choline; Drug Compounding; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Ionic Liquids; Ions; Naproxen; Solubility; Water | 2021 |
First trimester naproxen exposure and outcome of pregnancy - A German case series.
Topics: Abortion, Spontaneous; Anencephaly; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Female; Germany; Humans; Ibuprofen; Live Birth; Maternal Exposure; Naproxen; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, First; Pregnancy Trimester, Second; Stillbirth | 2021 |
Layered terbium hydroxides for simultaneous drug delivery and imaging.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caco-2 Cells; Cell Survival; Diclofenac; Drug Delivery Systems; Drug Liberation; Drug Stability; Erythrocytes; Female; HEK293 Cells; Hemolysis; Humans; Hydroxides; Ibuprofen; Ion Exchange; Naproxen; Optical Imaging; Rats, Wistar; Terbium | 2021 |
Adsorption removal of ibuprofen and naproxen from aqueous solution with Cu-doped Mil-101(Fe).
Topics: Adsorption; Humans; Ibuprofen; Naproxen; Spectroscopy, Fourier Transform Infrared; Water; Water Pollutants, Chemical | 2021 |
Facile and highly efficient three-phase single drop microextraction in-line coupled with capillary electrophoresis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Electrophoresis, Capillary; Humans; Ibuprofen; Ketoprofen; Naproxen | 2021 |
Cisplatin-cyclooxygenase inhibitor conjugates, free and immobilised in mesoporous silica SBA-15, prove highly potent against triple-negative MDA-MB-468 breast cancer cell line.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cisplatin; Cyclooxygenase Inhibitors; Female; Flurbiprofen; Humans; Ibuprofen; Molecular Structure; Naproxen; Platinum; Silicon Dioxide | 2022 |
Design and application of molecularly imprinted polymers for adsorption and environmental assessment of anti-inflammatory drugs in wastewater samples.
Topics: Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Emulsions; Ibuprofen; Molecular Imprinting; Molecularly Imprinted Polymers; Naproxen; Wastewater | 2022 |
Influence of the hydraulic retention time on the removal of emerging contaminants in an anoxic-aerobic algal-bacterial photobioreactor coupled with anaerobic digestion.
Topics: Acetaminophen; Anaerobiosis; Bacteria, Aerobic; Bioreactors; Ciprofloxacin; Dexamethasone; Enrofloxacin; Ibuprofen; Naproxen; Photobioreactors; Progesterone; Sewage; Sulfamethoxazole; Tetracyclines; Trimethoprim; Tylosin; Waste Disposal, Fluid | 2022 |
The Effects of Ibuprofen, Naproxen and Diclofenac on cell Apoptosis, Cell Proliferation and Histology Changes in Human Cholangiocarcinoma Cell Lines.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cell Line, Tumor; Cell Proliferation; Cholangiocarcinoma; Diclofenac; Humans; Ibuprofen; Lipids; Naproxen | 2022 |
Weak electrostimulation enhanced the microbial transformation of ibuprofen and naproxen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Electric Stimulation Therapy; Ibuprofen; NAD; Naproxen | 2022 |
Highly sensitive and simultaneous electrochemical determinations of non-steroidal anti-inflammatory drugs in water using nanostructured carbon-based paste electrodes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Electrochemical Techniques; Electrodes; Fullerenes; Graphite; Ibuprofen; Nanotubes, Carbon; Naproxen; Reproducibility of Results | 2022 |
Outcomes of nonsteroidal anti-inflammatory drug toxicosis treated with therapeutic plasma exchange in 62 dogs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dog Diseases; Dogs; Drug Overdose; Ibuprofen; Naproxen; Plasma Exchange; Retrospective Studies | 2022 |
Integrated adsorption and biological removal of the emerging contaminants ibuprofen, naproxen, atrazine, diazinon, and carbaryl in a horizontal tubular bioreactor.
Topics: Adsorption; Atrazine; Bioreactors; Carbaryl; Charcoal; Diazinon; Ibuprofen; Naproxen; Wastewater; Water; Water Pollutants, Chemical; Water Purification | 2022 |
Fecal indicator bacteria levels at a marine beach before, during, and after the COVID-19 shutdown period and associations with decomposing seaweed and human presence.
Topics: Acetaminophen; Animals; Bacteria; Bathing Beaches; Caffeine; COVID-19; Dogs; Enterococcus; Environmental Monitoring; Feces; Humans; Ibuprofen; Naproxen; Seaweed; Water; Water Microbiology | 2022 |
Medicine-Induced Acute Kidney Injury Findings from Spontaneous Reporting Systems, Sequence Symmetry Analysis and a Case-Control Study with a Focus on Medicines Used in Primary Care.
Topics: Acute Kidney Injury; Adverse Drug Reaction Reporting Systems; Amlodipine; Amphotericin B; Australia; Case-Control Studies; Ciprofloxacin; Diclofenac; Furosemide; Humans; Ibuprofen; Metformin; Naproxen; Omeprazole; Primary Health Care; Ramipril; Simvastatin; Spironolactone; Sulfamethoxazole; Telmisartan; Trimethoprim; Valacyclovir; Zoledronic Acid | 2022 |
2022 Taiwan Guidelines for Acute Treatment of Migraine.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Caffeine; Calcitonin Gene-Related Peptide Receptor Antagonists; Child; Diclofenac; Female; Headache; Humans; Ibuprofen; Migraine Disorders; Morphine Derivatives; Naproxen; Nasal Sprays; Pregnancy; Prochlorperazine; Taiwan; Tramadol; Tryptamines | 2022 |
Semi-quantification of the binding constant based on bond breaking in a combined acoustic-gravitational field.
Topics: Acoustics; Ciprofloxacin; Glycogen; Ibuprofen; Mannans; Naproxen; Serum Albumin, Bovine | 2022 |
Pharmaceuticals, natural and synthetic hormones and phenols in sediments from an eutrophic estuary, Jurujuba Sound, Guanabara Bay, Brazil.
Topics: Bays; Brazil; Diclofenac; Endocrine Disruptors; Environmental Monitoring; Estradiol; Estriol; Estrogens; Estrone; Estuaries; Gemfibrozil; Ibuprofen; Naproxen; Pharmaceutical Preparations; Phenols; Water Pollutants, Chemical | 2022 |
Preclinical comparison of antinociceptive effects between ibuprofen, diclofenac, naproxen, and acetaminophen on acid-stimulated body stretching and acid-depressed feeding behaviors in rats.
Topics: Acetaminophen; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Feeding Behavior; Ibuprofen; Lactic Acid; Male; Naproxen; Pain; Rats | 2022 |
Fully soluble polymeric foams for in-vial dried blood spot collection and analysis of acidic drugs by capillary electrophoresis.
Topics: Electrophoresis, Capillary; Ibuprofen; Ketoprofen; Naproxen; Solvents | 2023 |
Masking the Taste of Fixed-Dose Combination Drugs: Particular NSAIDs Can Efficiently Mask the Bitterness of Famotidine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Famotidine; Flurbiprofen; Ibuprofen; Naproxen; Taste | 2023 |
Water Maintains the UV-Vis Spectral Features During the Insertion of Anionic Naproxen and Ibuprofen into Model Cell Membranes.
Topics: Cell Membrane; Ibuprofen; Lipids; Naproxen; Quantum Theory; Water | 2023 |
Trends in pediatric nonprescription analgesic/antipyretic exposures during the COVID-19 pandemic.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Child; Child, Preschool; COVID-19; Female; Humans; Ibuprofen; Male; Naproxen; Nonprescription Drugs; Pandemics; Poison Control Centers; United States | 2023 |
Evaluation of the Defined Bacterial Consortium Efficacy in the Biodegradation of NSAIDs.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Naproxen; Sewage | 2023 |
Interactions of Nonsteroidal Antiinflammatory Drugs and Aspirin and Risk of Cardiovascular Disease in Patients With Osteoarthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Humans; Ibuprofen; Naproxen; Osteoarthritis | 2023 |
Impact of Lifestyle and Socioeconomic Position on the Association Between Non-steroidal Anti-inflammatory Drug Use and Major Adverse Cardiovascular Events: A Case-Crossover Study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cross-Over Studies; Diclofenac; Humans; Ibuprofen; Life Style; Myocardial Infarction; Naproxen; Risk Factors; Socioeconomic Factors | 2023 |
What do patients' efficacy and tolerability ratings of acute migraine medication tell us? Cross-sectional data from the DMKG Headache Registry.
Topics: Adult; Analgesics, Non-Narcotic; Cross-Sectional Studies; Female; Headache; Humans; Ibuprofen; Middle Aged; Migraine Disorders; Naproxen; Registries; Tryptamines | 2023 |
Effect of biosolids amendment on the fate and mobility of non-steroidal anti-inflammatory drugs (NSAIDs) in a field-based lysimeter cell study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biosolids; Ibuprofen; Ketoprofen; Naproxen; Sand; Soil; Soil Pollutants | 2023 |
The use of analgesics for intentional self-poisoning: Trends in U.S. poison center data.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Aspirin; Child; COVID-19; Female; Humans; Ibuprofen; Male; Naproxen; Pandemics; Poison Control Centers; Poisons; Young Adult | 2023 |
Impact of hemoglobin A1c level on the association between non-steroidal anti-inflammatory drug use and cardiovascular events in patients with type 2 diabetes: A population-based cohort study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Diabetes Mellitus, Type 2; Diclofenac; Glycated Hemoglobin; Humans; Ibuprofen; Myocardial Infarction; Naproxen; Risk Factors | 2023 |
Cardiovascular risks of continuing vs. initiating NSAIDs after first-time myocardial infarction or heart failure: a nationwide cohort study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Cohort Studies; Diclofenac; Heart Disease Risk Factors; Heart Failure; Humans; Ibuprofen; Myocardial Infarction; Naproxen; Risk Factors | 2023 |
Effect of salinity on the toxicity of diclofenac, ibuprofen and naproxen toward cyanobacterium Synechocystis salina.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Naproxen; Salinity; Water Pollutants, Chemical | 2023 |
Solar energy-based electromembrane extraction using agarose gel for the determination of nonsteroidal anti-inflammatory drugs from biological samples: An environmentally friendly strategy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Hydrogen-Ion Concentration; Ibuprofen; Limit of Detection; Membranes, Artificial; Naproxen; Sepharose; Solar Energy; Solvents | 2023 |
Oral Nonprescription Pain Medications for Adults.
Topics: Administration, Oral; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Naproxen; Nonprescription Drugs; Pain | 2023 |
Thermally-activated gelatin-chitosan-MOF hybrid aerogels for efficient removal of ibuprofen and naproxen.
Topics: Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Chitosan; Gelatin; Ibuprofen; Kinetics; Naproxen; Water Pollutants, Chemical | 2024 |