ibuprofen has been researched along with naloxone in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (22.22) | 18.7374 |
| 1990's | 3 (11.11) | 18.2507 |
| 2000's | 10 (37.04) | 29.6817 |
| 2010's | 8 (29.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strassburg, CP; Tukey, RH | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Chen, MZ; Han, QD; Wang, XA; Yang, LH | 1 |
| Breslow, MJ; Miller, CF; Nishijima, MK; Traystman, RJ | 1 |
| Ekström, BF; Kuenzig, M; Schwartz, SI | 1 |
| Almqvist, PM; Ekström, B; Haglund, U; Kuenzig, M; Schwartz, SI | 2 |
| Hamburger, SA; Judy, WV; Toth, PD | 1 |
| Chapman, RW; Chipkin, RE | 1 |
| Björkman, R | 1 |
| Forsling, ML; Yasin, SA | 1 |
| Altemeier, WA; Easley, RB | 1 |
| Buerkle, H; Dunbar, SA; Karamov, IG | 1 |
| Baisden, M; Bowles, WR; Hodges, JS; Jureidini, B; Ryan, JL; Swift, JQ | 1 |
4 review(s) available for ibuprofen and naloxone
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Central antinociceptive effects of non-steroidal anti-inflammatory drugs and paracetamol. Experimental studies in the rat.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Behavior, Animal; Brain; Chemoreceptor Cells; Diclofenac; Ibuprofen; Male; Mechanoreceptors; Naloxone; Nociceptors; Pain; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Serotonin; Spinal Cord; Thermoreceptors | 1995 |
1 trial(s) available for ibuprofen and naloxone
| Article | Year |
|---|---|
Gender differences in analgesia for endodontic pain.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Likelihood Functions; Linear Models; Male; Naloxone; Pain Measurement; Pain, Postoperative; Pentazocine; Periapical Periodontitis; Prospective Studies; Pulpitis; Root Canal Therapy; Sex Factors; Surveys and Questionnaires; Toothache | 2008 |
22 other study(ies) available for ibuprofen and naloxone
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
[Antiinflammatory drugs inhibit the elevation of plasma CGRP concentration in endotoxin shock in rats].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcitonin Gene-Related Peptide; Ibuprofen; Indomethacin; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Shock, Septic | 1991 |
Effect of naloxone and ibuprofen on organ blood flow during endotoxic shock in pig.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Hemodynamics; Ibuprofen; Microspheres; Naloxone; Regional Blood Flow; Shock, Septic; Swine; Thromboxane B2 | 1988 |
Pulmonary platelet trapping in Escherichia coli endotoxin-injected dogs treated with methylprednisolone, ibuprofen and naloxone.
Topics: Animals; Blood Platelets; Blood Pressure; Diarrhea; Dogs; Endotoxins; Escherichia coli; Female; Hematocrit; Ibuprofen; Leukocyte Count; Male; Methylprednisolone; Naloxone; Platelet Count; Respiratory Distress Syndrome; Shock, Septic | 1986 |
Effect of high dose corticosteroids alone or combined with other drugs on survival in septic shock.
Topics: Animals; Dogs; Drug Therapy, Combination; Endotoxins; Humans; Ibuprofen; Methylprednisolone; Naloxone; Shock, Septic | 1985 |
Increased survival of endotoxin-injected dogs treated with methylprednisolone, naloxone, and ibuprofen.
Topics: Animals; Blood Cell Count; Blood Pressure; Dogs; Drug Therapy, Combination; Endotoxins; Female; Ibuprofen; Male; Methylprednisolone; Naloxone; Shock, Septic; Time Factors | 1984 |
The effects of vasoactive mediator antagonists on endotoxic shock in dogs. I.
Topics: Animals; Blood Pressure; Disease Models, Animal; Dogs; Endorphins; Hemodynamics; Ibuprofen; Male; Naloxone; Prostaglandins; Shock, Septic; Vascular Resistance | 1984 |
Enkephalin heptapeptide (Tyr-Gly-Gly-Phe-Met-Arg-Phe)-induced bronchospasm in guinea pigs: a non-naloxone reversible phenomenon.
Topics: Animals; Bronchi; Chromones; Dose-Response Relationship, Drug; Enkephalin, Methionine; Guinea Pigs; Ibuprofen; Imidazoles; Male; Naloxone; Pressure; Trachea; Vagotomy | 1984 |
Mechanisms of melatonin inhibition of neurohypophysial hormone release from the rat hypothalamus in vitro.
Topics: Animals; Atenolol; Atropine; Haloperidol; Hypothalamus; Ibuprofen; In Vitro Techniques; Male; Mecamylamine; Melatonin; Naloxone; Oxytocin; Phentolamine; Rats; Rats, Wistar; Receptors, Neurotransmitter; Reproducibility of Results; Vasopressins | 1998 |
Central nervous system manifestations of an ibuprofen overdose reversed by naloxone.
Topics: Acidosis; Anti-Inflammatory Agents, Non-Steroidal; Antidotes; Central Nervous System; Central Nervous System Diseases; Drug Overdose; Female; Humans; Ibuprofen; Infant; Naloxone | 2000 |
The effect of spinal ibuprofen on opioid withdrawal in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Hyperalgesia; Ibuprofen; Injections, Spinal; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Pain Threshold; Rats; Rats, Sprague-Dawley; Reaction Time; Substance Withdrawal Syndrome | 2000 |