ibuprofen and naloxone

ibuprofen has been researched along with naloxone in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19906 (22.22)18.7374
1990's3 (11.11)18.2507
2000's10 (37.04)29.6817
2010's8 (29.63)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Chang, TK; Ensom, MH; Kiang, TK1
Lombardo, F; Obach, RS; Waters, NJ1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chen, MZ; Han, QD; Wang, XA; Yang, LH1
Breslow, MJ; Miller, CF; Nishijima, MK; Traystman, RJ1
Ekström, BF; Kuenzig, M; Schwartz, SI1
Almqvist, PM; Ekström, B; Haglund, U; Kuenzig, M; Schwartz, SI2
Hamburger, SA; Judy, WV; Toth, PD1
Chapman, RW; Chipkin, RE1
Björkman, R1
Forsling, ML; Yasin, SA1
Altemeier, WA; Easley, RB1
Buerkle, H; Dunbar, SA; Karamov, IG1
Baisden, M; Bowles, WR; Hodges, JS; Jureidini, B; Ryan, JL; Swift, JQ1

Reviews

4 review(s) available for ibuprofen and naloxone

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Central antinociceptive effects of non-steroidal anti-inflammatory drugs and paracetamol. Experimental studies in the rat.
    Acta anaesthesiologica Scandinavica. Supplementum, 1995, Volume: 103

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Behavior, Animal; Brain; Chemoreceptor Cells; Diclofenac; Ibuprofen; Male; Mechanoreceptors; Naloxone; Nociceptors; Pain; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Serotonin; Spinal Cord; Thermoreceptors

1995

Trials

1 trial(s) available for ibuprofen and naloxone

ArticleYear
Gender differences in analgesia for endodontic pain.
    Journal of endodontics, 2008, Volume: 34, Issue:5

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Likelihood Functions; Linear Models; Male; Naloxone; Pain Measurement; Pain, Postoperative; Pentazocine; Periapical Periodontitis; Prospective Studies; Pulpitis; Root Canal Therapy; Sex Factors; Surveys and Questionnaires; Toothache

2008

Other Studies

22 other study(ies) available for ibuprofen and naloxone

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
[Antiinflammatory drugs inhibit the elevation of plasma CGRP concentration in endotoxin shock in rats].
    Sheng li xue bao : [Acta physiologica Sinica], 1991, Volume: 43, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcitonin Gene-Related Peptide; Ibuprofen; Indomethacin; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Shock, Septic

1991
Effect of naloxone and ibuprofen on organ blood flow during endotoxic shock in pig.
    The American journal of physiology, 1988, Volume: 255, Issue:1 Pt 2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Hemodynamics; Ibuprofen; Microspheres; Naloxone; Regional Blood Flow; Shock, Septic; Swine; Thromboxane B2

1988
Pulmonary platelet trapping in Escherichia coli endotoxin-injected dogs treated with methylprednisolone, ibuprofen and naloxone.
    Acta chirurgica Scandinavica, 1986, Volume: 152

    Topics: Animals; Blood Platelets; Blood Pressure; Diarrhea; Dogs; Endotoxins; Escherichia coli; Female; Hematocrit; Ibuprofen; Leukocyte Count; Male; Methylprednisolone; Naloxone; Platelet Count; Respiratory Distress Syndrome; Shock, Septic

1986
Effect of high dose corticosteroids alone or combined with other drugs on survival in septic shock.
    Acta chirurgica Scandinavica. Supplementum, 1985, Volume: 526

    Topics: Animals; Dogs; Drug Therapy, Combination; Endotoxins; Humans; Ibuprofen; Methylprednisolone; Naloxone; Shock, Septic

1985
Increased survival of endotoxin-injected dogs treated with methylprednisolone, naloxone, and ibuprofen.
    Circulatory shock, 1984, Volume: 14, Issue:2

    Topics: Animals; Blood Cell Count; Blood Pressure; Dogs; Drug Therapy, Combination; Endotoxins; Female; Ibuprofen; Male; Methylprednisolone; Naloxone; Shock, Septic; Time Factors

1984
The effects of vasoactive mediator antagonists on endotoxic shock in dogs. I.
    Circulatory shock, 1984, Volume: 12, Issue:4

    Topics: Animals; Blood Pressure; Disease Models, Animal; Dogs; Endorphins; Hemodynamics; Ibuprofen; Male; Naloxone; Prostaglandins; Shock, Septic; Vascular Resistance

1984
Enkephalin heptapeptide (Tyr-Gly-Gly-Phe-Met-Arg-Phe)-induced bronchospasm in guinea pigs: a non-naloxone reversible phenomenon.
    Life sciences, 1984, May-07, Volume: 34, Issue:19

    Topics: Animals; Bronchi; Chromones; Dose-Response Relationship, Drug; Enkephalin, Methionine; Guinea Pigs; Ibuprofen; Imidazoles; Male; Naloxone; Pressure; Trachea; Vagotomy

1984
Mechanisms of melatonin inhibition of neurohypophysial hormone release from the rat hypothalamus in vitro.
    Brain research bulletin, 1998, Volume: 45, Issue:1

    Topics: Animals; Atenolol; Atropine; Haloperidol; Hypothalamus; Ibuprofen; In Vitro Techniques; Male; Mecamylamine; Melatonin; Naloxone; Oxytocin; Phentolamine; Rats; Rats, Wistar; Receptors, Neurotransmitter; Reproducibility of Results; Vasopressins

1998
Central nervous system manifestations of an ibuprofen overdose reversed by naloxone.
    Pediatric emergency care, 2000, Volume: 16, Issue:1

    Topics: Acidosis; Anti-Inflammatory Agents, Non-Steroidal; Antidotes; Central Nervous System; Central Nervous System Diseases; Drug Overdose; Female; Humans; Ibuprofen; Infant; Naloxone

2000
The effect of spinal ibuprofen on opioid withdrawal in the rat.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Hyperalgesia; Ibuprofen; Injections, Spinal; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Pain Threshold; Rats; Rats, Sprague-Dawley; Reaction Time; Substance Withdrawal Syndrome

2000