ibuprofen has been researched along with n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (34.48) | 18.2507 |
| 2000's | 16 (55.17) | 29.6817 |
| 2010's | 3 (10.34) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bohlin, L; Danielson, H; Noreen, Y; Perera, P; Ringbom, T | 1 |
| Bohlin, L; Noreen, Y; Perera, P; Ringbom, T; Segura, L | 1 |
| Backlund, A; Bohlin, L; Gottfries, J; Larsson, J | 1 |
| Choi, HE; Choi, MJ; Jin, JH; Kang, SM; Kim, KJ; Kim, M; Lee, JY; Lee, KT; Shin, JS | 1 |
| An, JY; Kim, NJ; Kim, SW; Lee, HH; Lee, J; Lee, KT; Park, JS; Shin, JS; Son, SH; Yoo, HS; Yu, J | 1 |
| Arai, I; Futaki, N; Hamasaka, Y; Higuchi, S; Iizuka, H; Otomo, S; Yoshikawa, K | 1 |
| Crews, BC; Kalgutkar, AS; Marnett, LJ | 1 |
| Hara, A; Ino, N; Mori, H; Niwa, M; Yoshimi, N | 1 |
| Bell, RL; Hulkower, KI; Otis, ER; Wernimont, AK | 1 |
| Lau, HY; Stenton, GR | 1 |
| Cryer, HG; Fu, M; Lo, CJ; Lo, FR | 1 |
| Langenbach, R; Morham, SG; Young, DA; Zhang, X | 1 |
| Wallace, JL | 1 |
| Attiga, FA; Fernandez, PM; Manyak, MJ; Patierno, SR; Weeraratna, AT | 1 |
| Feinstein, DL; Heneka, MT; Klockgether, T | 1 |
| Danon, A; Rimon, G; Rosenstock, M; Rubin, M | 1 |
| Abboud, HE; Bonacchi, A; Efsen, E; Gentilini, P; Laffi, G; Marra, F; Pastacaldi, S; Pinzani, M; Tosti-Guerra, C; Valente, AJ; Wenzel, UO | 1 |
| Aisen, PS; Mukherjee, P; Pasinetti, GM; Rachita, C | 1 |
| Kim, JM; Manchanda, R; Tsang, BK | 1 |
| Andrews, J; Andrews, P; Djakiew, D; Krygier, S | 1 |
| Burde, T; Rimon, G | 1 |
| Calixto, JB; El Sayah, M | 1 |
| Coleman, CN; Palayoor, ST; Tofilon, PJ | 1 |
| Bari, F; Domoki, F; Nagy, K; Temesvári, P | 1 |
| Beaulieu, P; De Léan, A; Guindon, J; LoVerme, J; Piomelli, D | 1 |
| Han, JA; Kim, SR; Lee, ME; Park, JH; Park, JS; Park, SC | 1 |
| Cerna, D; Coleman, CN; Falduto, MT; John-Aryankalayil, M; Magnuson, SR; Palayoor, ST | 1 |
| Hébert, RL; Nasrallah, R; Robertson, SJ | 1 |
| Cerna, D; Coleman, CN; Falduto, MT; J-Aryankalayil, M; Magnuson, SR; Makinde, AY; Palayoor, ST | 1 |
1 review(s) available for ibuprofen and n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide
| Article | Year |
|---|---|
Distribution and expression of cyclooxygenase (COX) isoenzymes, their physiological roles, and the categorization of nonsteroidal anti-inflammatory drugs (NSAIDs).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Controlled Clinical Trials as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Etodolac; Gene Expression; Humans; Ibuprofen; Indomethacin; Isoenzymes; Meloxicam; Membrane Proteins; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Thiazines; Thiazoles | 1999 |
28 other study(ies) available for ibuprofen and n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide
| Article | Year |
|---|---|
Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis.
Topics: Animals; Biological Assay; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Kinetics; Placenta; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sheep | 1998 |
Ursolic acid from Plantago major, a selective inhibitor of cyclooxygenase-2 catalyzed prostaglandin biosynthesis.
Topics: Animals; Cattle; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; In Vitro Techniques; Isoenzymes; Plantago; Plants, Medicinal; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sheep; Triterpenes; Ursolic Acid | 1998 |
Expanding the ChemGPS chemical space with natural products.
Topics: Biological Products; Combinatorial Chemistry Techniques; Computer Graphics; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship | 2005 |
Synthesis, biological evaluation, and docking analysis of a novel family of 1-methyl-1H-pyrrole-2,5-diones as highly potent and selective cyclooxygenase-2 (COX-2) inhibitors.
Topics: Anti-Inflammatory Agents; Benzoquinones; Binding Sites; Catalytic Domain; Cell Survival; Cells, Cultured; Cyclooxygenase 2 Inhibitors; Hydrogen Bonding; Inhibitory Concentration 50; Macrophages; Models, Molecular; Molecular Docking Simulation; Protein Binding; Pyrroles; Structure-Activity Relationship | 2014 |
Identification and structure activity relationship of novel flavone derivatives that inhibit the production of nitric oxide and PGE
Topics: Animals; Anti-Inflammatory Agents; Dinoprostone; Flavones; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; RAW 264.7 Cells; Structure-Activity Relationship | 2017 |
NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Cyclooxygenase Inhibitors; Diclofenac; Edema; Fever; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Nitrobenzenes; Pain; Phenylpropionates; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Stomach Ulcer; Sulfonamides | 1993 |
Kinetics of the interaction of nonsteroidal antiinflammatory drugs with prostaglandin endoperoxide synthase-1 studied by limited proteolysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclooxygenase Inhibitors; Hemin; Ibuprofen; Kinetics; Molecular Structure; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostanoic Acids; Protein Binding; Protein Conformation; Sulfonamides; Thiazoles; Trypsin | 1996 |
Apoptosis induced by NS-398, a selective cyclooxygenase-2 inhibitor, in human colorectal cancer cell lines.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Division; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; Ibuprofen; Indomethacin; Isoenzymes; Membrane Proteins; Nitrobenzenes; Piroxicam; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Tumor Cells, Cultured | 1997 |
Stimulus dependence of non-steroidal antiinflammatory drug potency in a cellular assay of prostaglandin H synthase-2.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Drug Interactions; Humans; Ibuprofen; Indans; Indomethacin; Interleukin-1; Meclofenamic Acid; Nitrobenzenes; Okadaic Acid; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Sulfonamides; Tumor Necrosis Factor-alpha | 1997 |
Effects of non-steroidal anti-inflammatory drugs and cyclooxygenase-2 specific inhibitors on mediator release from rat peritoneal mast cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Enzyme Activation; Flurbiprofen; Histamine Release; Ibuprofen; Immunoglobulin E; Indans; Indomethacin; Isoenzymes; Male; Mast Cells; Naphthaleneacetic Acids; Nitrobenzenes; Peritoneal Cavity; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Sulfonamides | 1998 |
Regulation of macrophage eicosanoid generation is dependent on nuclear factor kappaB.
Topics: Animals; Cell Line; Cyclooxygenase Inhibitors; Dinoprostone; Escherichia coli; Gene Expression Regulation, Enzymologic; Ibuprofen; Lipopolysaccharides; Macrophages; Mice; Multiple Trauma; NF-kappa B; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Tosylphenylalanyl Chloromethyl Ketone; Transcriptional Activation | 1998 |
Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arachidonic Acid; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Embryo, Mammalian; Fibroblasts; Ibuprofen; Indomethacin; Isoenzymes; Membrane Proteins; Mice; Mice, Knockout; Nitrobenzenes; Oncogene Proteins, Viral; Piroxicam; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins p21(ras); RNA, Messenger; Simian virus 40; Sulfonamides; Sulindac | 1999 |
Inhibitors of prostaglandin synthesis inhibit human prostate tumor cell invasiveness and reduce the release of matrix metalloproteinases.
Topics: 3T3 Cells; Acetophenones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cell Movement; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Eicosanoids; Enzyme Inhibitors; Humans; Ibuprofen; Isoenzymes; Lipoxygenase; Lipoxygenase Inhibitors; Male; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Membrane Proteins; Mice; Neoplasm Invasiveness; Nitrobenzenes; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostatic Neoplasms; Sulfonamides; Tissue Inhibitor of Metalloproteinases; Tumor Cells, Cultured; Umbelliferones | 2000 |
Peroxisome proliferator-activated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase expression and cell death in vivo.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Death; Cerebellum; Chromans; Cyclooxygenase Inhibitors; Down-Regulation; Ibuprofen; Immunohistochemistry; In Situ Nick-End Labeling; Interferon-gamma; Ligands; Lipopolysaccharides; Male; Microinjections; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrobenzenes; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Sulfonamides; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2000 |
Prostaglandin H synthase-2 inhibitors interfere with prostaglandin H synthase-1 inhibition by nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Cattle; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Ibuprofen; Indomethacin; Isoenzymes; Male; Microsomes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sulfonamides; Thiophenes | 2001 |
Agonist-specific regulation of monocyte chemoattractant protein-1 expression by cyclooxygenase metabolites in hepatic stellate cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cells, Cultured; Chemokine CCL2; Cyclic AMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Gene Expression; Humans; Ibuprofen; Indomethacin; Interleukin-1; Isoenzymes; Liver; Membrane Proteins; NF-kappa B; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2001 |
Non-steroidal anti-inflammatory drugs protect against chondrocyte apoptotic death.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Caspase 3; Caspases; Cell Line; Cell Nucleus; Cell Survival; Chondrocytes; Cyclooxygenase Inhibitors; Cytochrome c Group; Dose-Response Relationship, Drug; Ibuprofen; Nitrobenzenes; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; RNA, Messenger; Staurosporine; Sulfonamides; Time Factors | 2001 |
Role of prostaglandins in the suppression of apoptosis in hen granulosa cells by transforming growth factor alpha.
Topics: Alprostadil; Animals; Apoptosis; Arachidonic Acid; Arachidonic Acids; Aristolochic Acids; Cells, Cultured; Chickens; Chromatin; Culture Media, Serum-Free; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; DNA Fragmentation; Enzyme Inhibitors; Female; Granulosa Cells; Ibuprofen; Nitrobenzenes; Phenanthrenes; Phospholipases A; Prostaglandins; Prostaglandins E; Prostaglandins F; Sulfonamides; Transforming Growth Factor alpha | 2001 |
Superior effectiveness of ibuprofen compared with other NSAIDs for reducing the survival of human prostate cancer cells.
Topics: Acetaminophen; Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Division; Humans; Ibuprofen; In Situ Nick-End Labeling; Male; Mice; Naproxen; Nitrobenzenes; Prostatic Neoplasms; Sulfonamides; Tumor Cells, Cultured | 2002 |
On the interaction of specific prostaglandin H synthase-2 inhibitors with prostaglandin H synthase-1.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Binding, Competitive; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ibuprofen; In Vitro Techniques; Indomethacin; Isoenzymes; Male; Microsomes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sheep; Sulfonamides | 2002 |
Study of the mechanisms involved in the bradykinin-induced contraction of the pig iris sphincter muscle in vitro.
Topics: Animals; Atropine; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanethidine; Ibuprofen; Imidazoles; In Vitro Techniques; Indomethacin; Iris; Kallidin; Muscle Contraction; Muscle, Smooth; Nitrobenzenes; Propionates; Quinolines; Salicylates; Sulfonamides; Swine; Tetrodotoxin; Thromboxane-A Synthase | 2003 |
Ibuprofen-mediated reduction of hypoxia-inducible factors HIF-1alpha and HIF-2alpha in prostate cancer cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Basic Helix-Loop-Helix Transcription Factors; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation, Neoplastic; Glucose Transporter Type 1; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Ibuprofen; Isoenzymes; Ketorolac; Male; Membrane Proteins; Monosaccharide Transport Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostatic Neoplasms; Sulfonamides; Time Factors; Trans-Activators; Transcription Factors; Up-Regulation; Vascular Endothelial Growth Factor A | 2003 |
Selective inhibitors differentially affect cyclooxygenase-dependent pial arteriolar responses in newborn pigs.
Topics: Acetaminophen; Animals; Animals, Newborn; Arterioles; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Hypercapnia; Hypotension; Ibuprofen; Indomethacin; Male; Methacholine Chloride; Nitrobenzenes; Pia Mater; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Swine; Vasoconstriction; Vasodilation | 2005 |
Synergistic antinociceptive effects of anandamide, an endocannabinoid, and nonsteroidal anti-inflammatory drugs in peripheral tissue: a role for endogenous fatty-acid ethanolamides?
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Capsaicin; Chromatography, High Pressure Liquid; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Edema; Endocannabinoids; Formaldehyde; Ibuprofen; Lactones; Male; Mass Spectrometry; Nitrobenzenes; Pain Measurement; Peripheral Nervous System; Polyunsaturated Alkamides; Rats; Rats, Wistar; Sulfonamides; Sulfones; TRPV Cation Channels | 2006 |
Selective COX-2 inhibitors modulate cellular senescence in human dermal fibroblasts in a catalytic activity-independent manner.
Topics: Aspirin; Caveolin 1; Celecoxib; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Fibroblasts; Flurbiprofen; Humans; Ibuprofen; Kinetics; Models, Biological; NF-kappa B; Nitrobenzenes; Pyrazoles; Reactive Oxygen Species; Skin; Skin Aging; Sulfonamides; Tumor Suppressor Protein p53 | 2008 |
NS-398, ibuprofen, and cyclooxygenase-2 RNA interference produce significantly different gene expression profiles in prostate cancer cells.
Topics: Angiopoietin-Like Protein 4; Angiopoietins; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Hot Temperature; Humans; Ibuprofen; Male; Matrix Metalloproteinase 3; Nitrobenzenes; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; RNA Interference; Sulfonamides | 2009 |
Chronic COX inhibition reduces diabetes-induced hyperfiltration, proteinuria, and renal pathological markers in 36-week B6-Ins2(Akita) mice.
Topics: Albuminuria; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Body Weight; Creatinine; Cyclin-Dependent Kinase Inhibitor p27; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Disease Models, Animal; Fibronectins; Ibuprofen; Kidney; Kidney Failure, Chronic; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nitrobenzenes; Organ Size; Prostaglandins; Sulfonamides | 2009 |
Gene expression profile of coronary artery cells treated with nonsteroidal anti-inflammatory drugs reveals off-target effects.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Celecoxib; Cell Proliferation; Cells, Cultured; Coronary Vessels; Dose-Response Relationship, Drug; Endothelial Cells; Gene Expression Profiling; Gene Expression Regulation; Humans; Ibuprofen; Microarray Analysis; Molecular Targeted Therapy; Muscle, Smooth, Vascular; Nitrobenzenes; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides | 2012 |