ibuprofen and mk 0663

ibuprofen has been researched along with mk 0663 in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (29.17)29.6817
2010's13 (54.17)24.3611
2020's4 (16.67)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Castrejón-Flores, JL; Franco-Hernández, MO; García-Aranda, MI; García-Báez, EV; Gómez-Castro, CZ; Gómez-Gómez, YM; Gonzalez-Padilla, JE; Padilla-Martínez, II; Rosales-Hernández, MC1
Ouellet, M; Percival, MD; Riendeau, D1
Bowen, B; Callegari, P; Evans, J; Harper, S; Hunt, RH; James, C; Quan, H; Rashid, F; Yu, C1
Evans, JK; Harper, S; Hunt, RH; Lee, M; Oxenius, B; Quan, H; Watson, DJ; Yu, C1
Aversano, ML; Boice, JA; Ko, A; Murphy, FT; Reicin, AS; Sheldon, EA; Wiesenhutter, CW; Wittmer, BA1
Berrocal, A; Boice, JA; Cichanowitz, N; Fidelholtz, JL; Ko, A; Littlejohn, TW; Miranda, P; Puopolo, A; Reicin, AS1
Bandy, DP; Boice, J; Christensen, SE; Daniels, SE; Liu, H; Losada, MC; Mehta, A; Peloso, PM1
Derry, S; McQuay, HJ; Moore, AR; Paine, J; Straube, S1
Janovsky, M; Krsiak, M1
Micu, MC; Micu, R; Ostensen, M1
Blanca, M; Blanca-López, N; Campo, P; Canto, G; Doña, I; Fernández, J; Gómez, AI; Jagemann, LR; Laguna, JJ; Rondón, C; Rosado, A; Torres, MJ1
Kasemier, J; Meek, IL; Movig, KL; van de Laar, MA; Vonkeman, HE1
Chen, L; Chitkara, DK; Curtis, SP; Mehta, A; Minkowitz, HS; Papanicolaou, DA; Peloso, PM; Rawal, N; Shah, S; Viscusi, E1
Chang, Q; Di, W; Hua, Q; Li, X; Liu, J; Mehta, A; Yan, L; Yao, Y; Yu, Q; Yu, W; Zhang, X; Zhang, Y; Zhu, X; Zou, Q1
Dulski, M; Paluch, M; Rams-Baron, M; Ratuszna, A; Wojnarowska, Z1
Baglie, S; Baller, EM; Franco, GC; Gevert, MV; Lupepsa, AC; Moro, MG; Sanchez, PK; Tostes, AF1
Khehra, HS; Piepho, HP; Sandhu, SS1
Albuquerque, AFM; Bezerra, MM; Chaves, HV; Costa, FWG; de Barros Silva, PG; de Lima, BB; do Val, DR; Fonteles, CSR; Pereira, KMA; Ribeiro, TR; Soares, ECS1
Bojkova, D; Charlesworth, B; Ciesek, S; Cinatl, J; de Bruin, N; Gribbon, P; Kannt, A; Laughey, WF; Lodhi, I; Pennick, G; Reus, P; Schiffmann, S; Schneider, AK; Sinclair, S; Talmon, S1
Hjemdahl, P; Stiller, CO1
Alvarenga-Brant, R; Costa, FO; Cota, LOM; Esteves-Lima, RP; Mattos-Pereira, GH1

Reviews

3 review(s) available for ibuprofen and mk 0663

ArticleYear
Minimum efficacy criteria for comparisons between treatments using individual patient meta-analysis of acute pain trials: examples of etoricoxib, paracetamol, ibuprofen, and ibuprofen/paracetamol combinations after third molar extraction.
    Pain, 2011, Volume: 152, Issue:5

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Double-Blind Method; Drug Therapy, Combination; Etoricoxib; Female; Humans; Ibuprofen; Male; Molar, Third; Pain, Postoperative; Pyridines; Randomized Controlled Trials as Topic; Sulfones; Tooth Extraction; Treatment Outcome; Young Adult

2011
Comparing the effectiveness profile of pharmacological interventions used for orthodontic pain relief: an arm-based multilevel network meta-analysis of longitudinal data.
    European journal of orthodontics, 2017, Nov-30, Volume: 39, Issue:6

    Topics: Acetaminophen; Analgesics; Drug Administration Schedule; Etoricoxib; Humans; Ibuprofen; Network Meta-Analysis; Orthodontics, Corrective; Pain; Pain Management; Randomized Controlled Trials as Topic

2017
Lessons from 20 years with COX-2 inhibitors: Importance of dose-response considerations and fair play in comparative trials.
    Journal of internal medicine, 2022, Volume: 292, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Fibrinolytic Agents; Humans; Ibuprofen; Lactones; Naproxen; Prostaglandins; Prostaglandins I; Sulfones; Thromboxanes

2022

Trials

11 trial(s) available for ibuprofen and mk 0663

ArticleYear
Complementary studies of the gastrointestinal safety of the cyclo-oxygenase-2-selective inhibitor etoricoxib.
    Alimentary pharmacology & therapeutics, 2003, Volume: 17, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Duodenal Ulcer; Etoricoxib; Female; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Isoenzymes; Male; Membrane Proteins; Middle Aged; Occult Blood; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Pyridines; Stomach Ulcer; Sulfones

2003
The gastrointestinal safety of the COX-2 selective inhibitor etoricoxib assessed by both endoscopy and analysis of upper gastrointestinal events.
    The American journal of gastroenterology, 2003, Volume: 98, Issue:8

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Endoscopy; Etoricoxib; Female; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Incidence; Isoenzymes; Male; Membrane Proteins; Meta-Analysis as Topic; Middle Aged; Peptic Ulcer; Peptic Ulcer Perforation; Prostaglandin-Endoperoxide Synthases; Pyridines; Sulfones; Treatment Outcome

2003
Evaluation of the comparative efficacy of etoricoxib and ibuprofen for treatment of patients with osteoarthritis: A randomized, double-blind, placebo-controlled trial.
    Mayo Clinic proceedings, 2005, Volume: 80, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Double-Blind Method; Etoricoxib; Female; Humans; Ibuprofen; Male; Middle Aged; Osteoarthritis; Pyridines; Sulfones

2005
A randomized placebo-controlled trial comparing the efficacy of etoricoxib 30 mg and ibuprofen 2400 mg for the treatment of patients with osteoarthritis.
    Osteoarthritis and cartilage, 2007, Volume: 15, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Cyclooxygenase Inhibitors; Double-Blind Method; Etoricoxib; Female; Humans; Ibuprofen; Male; Middle Aged; Osteoarthritis; Pain Measurement; Placebos; Pyridines; Statistics as Topic; Sulfones; Treatment Outcome

2007
Evaluation of the dose range of etoricoxib in an acute pain setting using the postoperative dental pain model.
    The Clinical journal of pain, 2011, Volume: 27, Issue:1

    Topics: Acetaminophen; Adolescent; Adult; Anesthesia, Dental; Anti-Inflammatory Agents, Non-Steroidal; Codeine; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Etoricoxib; Female; Humans; Ibuprofen; Least-Squares Analysis; Male; Molar, Third; Pain; Pain Measurement; Pain, Postoperative; Pyridines; Sulfones; Tooth Extraction; Tooth, Impacted; Treatment Outcome; Young Adult

2011
Response to a selective COX-2 inhibitor in patients with urticaria/angioedema induced by nonsteroidal anti-inflammatory drugs.
    Allergy, 2011, Volume: 66, Issue:11

    Topics: Acetaminophen; Adolescent; Adult; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2 Inhibitors; Drug Hypersensitivity; Etoricoxib; Humans; Hypersensitivity, Immediate; Ibuprofen; Pyridines; Single-Blind Method; Sulfones; Urticaria; Young Adult

2011
Interference of NSAIDs with the thrombocyte inhibitory effect of aspirin: a placebo-controlled, ex vivo, serial placebo-controlled serial crossover study.
    European journal of clinical pharmacology, 2013, Volume: 69, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Administration Schedule; Drug Interactions; Etoricoxib; Female; Humans; Ibuprofen; Male; Meloxicam; Middle Aged; Naproxen; Netherlands; Platelet Aggregation Inhibitors; Platelet Function Tests; Prospective Studies; Pyridines; Risk Assessment; Sulfones; Thiazines; Thiazoles; Time Factors; Young Adult

2013
Evaluation of etoricoxib in patients undergoing total knee replacement surgery in a double-blind, randomized controlled trial.
    BMC musculoskeletal disorders, 2013, Oct-24, Volume: 14

    Topics: Aged; Arthroplasty, Replacement, Knee; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Etoricoxib; Female; Humans; Ibuprofen; Male; Middle Aged; Morphine; Narcotics; Pain, Postoperative; Pyridines; Sulfones

2013
Etoricoxib in the treatment of primary dysmenorrhea in Chinese patients: a randomized controlled trial.
    Current medical research and opinion, 2014, Volume: 30, Issue:9

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; China; Cross-Over Studies; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Dysmenorrhea; Etoricoxib; Female; Humans; Ibuprofen; Pain Measurement; Pyridines; Severity of Illness Index; Sulfones; Treatment Outcome

2014
Effect of pre-emptive analgesia on clinical parameters and tissue levels of TNF-α and IL-1β in third molar surgery: a triple-blind, randomized, placebo-controlled study.
    International journal of oral and maxillofacial surgery, 2017, Volume: 46, Issue:12

    Topics: Adolescent; Adult; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Cyclooxygenase 2 Inhibitors; Etoricoxib; Female; Humans; Ibuprofen; Interleukin-1beta; Male; Molar, Third; Pain Management; Pain Measurement; Pain, Postoperative; Placebos; Pyridines; Sulfones; Tooth Extraction; Treatment Outcome; Tumor Necrosis Factor-alpha

2017
Preemptive effects of etoricoxib, acetaminophen, nimesulide, and ibuprofen on postoperative pain management after single-implant surgery: A randomized clinical trial.
    Clinical oral implants research, 2023, Volume: 34, Issue:11

    Topics: Acetaminophen; Dental Implants; Double-Blind Method; Etoricoxib; Female; Humans; Ibuprofen; Male; Middle Aged; Pain, Postoperative

2023

Other Studies

10 other study(ies) available for ibuprofen and mk 0663

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Anti-inflammatory effect and inhibition of nitric oxide production by targeting COXs and iNOS enzymes with the 1,2-diphenylbenzimidazole pharmacophore.
    Bioorganic & medicinal chemistry, 2020, 05-01, Volume: 28, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzimidazoles; Cattle; Cyclooxygenase 1; Cyclooxygenase 2; Dose-Response Relationship, Drug; Edema; Enzyme Inhibitors; Humans; Inflammation; Male; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Structure-Activity Relationship

2020
Investigational COX-2 inhibitor relieves pain in dental model.
    Current pain and headache reports, 2001, Volume: 5, Issue:1

    Topics: Adolescent; Adult; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Etoricoxib; Humans; Ibuprofen; Middle Aged; Pain; Pyridines; Randomized Controlled Trials as Topic; Sulfones; Tooth Extraction; Treatment Outcome

2001
A high level of cyclooxygenase-2 inhibitor selectivity is associated with a reduced interference of platelet cyclooxygenase-1 inactivation by aspirin.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Dec-04, Volume: 98, Issue:25

    Topics: Acetylation; Animals; Aspirin; Blood Platelets; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Etoricoxib; Humans; Ibuprofen; In Vitro Techniques; Isoenzymes; Isoxazoles; Lactones; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Pyridines; Sheep; Sulfonamides; Sulfones

2001
Codeine did not increase analgesic efficacy of coxibs in contrast to that of paracetamol or ibuprofen: isobolographic analysis in mice.
    Neuro endocrinology letters, 2011, Volume: 32, Issue:2

    Topics: Acetaminophen; Acetic Acid; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Celecoxib; Codeine; Cyclooxygenase 2 Inhibitors; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Etoricoxib; Ibuprofen; Male; Mice; Mice, Inbred Strains; Models, Animal; Pain; Pyrazoles; Pyridines; Regression Analysis; Sulfonamides; Sulfones

2011
Luteinized unruptured follicle syndrome increased by inactive disease and selective cyclooxygenase 2 inhibitors in women with inflammatory arthropathies.
    Arthritis care & research, 2011, Volume: 63, Issue:9

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Chi-Square Distribution; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Female; Fertility; Humans; Ibuprofen; Infertility, Female; Inflammation; Norway; Ovarian Follicle; Ovulation; Pregnancy; Prospective Studies; Pyridines; Rheumatic Diseases; Risk Assessment; Risk Factors; Sulfones; Ultrasonography

2011
Evidence of slow Debye-like relaxation in the anti-inflammatory agent etoricoxib.
    Physical review. E, Statistical, nonlinear, and soft matter physics, 2015, Volume: 92, Issue:2

    Topics: Computer Simulation; Cyclooxygenase 2 Inhibitors; Dielectric Spectroscopy; Etoricoxib; Hydrogen Bonding; Ibuprofen; Models, Chemical; Protons; Pyridines; Sulfones; Temperature

2015
Gastric and renal effects of COX-2 selective and non-selective NSAIDs in rats receiving low-dose aspirin therapy.
    Brazilian oral research, 2016, Nov-28, Volume: 30, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Creatinine; Cyclooxygenase 2 Inhibitors; Etoricoxib; Gastric Mucosa; Ibuprofen; Kidney; Kidney Diseases; Male; Platelet Aggregation Inhibitors; Pyridines; Random Allocation; Rats, Wistar; Risk Factors; Stomach Diseases; Sulfones; Time Factors; Treatment Outcome

2016
Ibuprofen, Flurbiprofen, Etoricoxib or Paracetamol Do Not Influence ACE2 Expression and Activity In Vitro or in Mice and Do Not Exacerbate In-Vitro SARS-CoV-2 Infection.
    International journal of molecular sciences, 2022, Jan-19, Volume: 23, Issue:3

    Topics: Acetaminophen; Angiotensin-Converting Enzyme 2; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caco-2 Cells; COVID-19; Disease Progression; Enzyme Activation; Etoricoxib; Flurbiprofen; Gene Expression Regulation, Enzymologic; Humans; Ibuprofen; Male; Mice; Mice, Inbred C57BL; SARS-CoV-2; Virus Internalization

2022