ibuprofen and midazolam

ibuprofen has been researched along with midazolam in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (45.45)29.6817
2010's10 (45.45)24.3611
2020's2 (9.09)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ong, CK; Seymour, RA; Tan, JM1
Allen, RH; Fitzmaurice, G; Goldberg, AB; Kumar, D; Lifford, KL1
Britto, LR; Guelmann, M; Soares, F; Vertucci, FJ1
Chandra, A; Colborn, DK; Hoberman, A; Hooper, EG; Kurs-Lasky, M; Reis, EC; Rockette, HE; Shaikh, N1
Aarons, L; Johnson, TN; Ogungbenro, K; Rostami-Hodjegan, A; Salem, F; Vajjah, P1
Allorto, NL; Clarke, DL; Wall, SL1
Abduljalil, K; Jamei, M; Johnson, TN; Pan, X; Pansari, A1
Banzi, R; Bruschettini, M; Calevo, MG; Ley, D; Paraskevas, T; Romantsik, O; Stróżyk, A1

Reviews

2 review(s) available for ibuprofen and midazolam

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacological pain and sedation interventions for the prevention of intraventricular hemorrhage in preterm infants on assisted ventilation - an overview of systematic reviews.
    The Cochrane database of systematic reviews, 2023, 08-11, Volume: 8

    Topics: Acetaminophen; Analgesics, Opioid; Cerebral Hemorrhage; Female; Heroin; Humans; Ibuprofen; Infant, Newborn; Infant, Premature; Midazolam; Pain; Perinatal Death; Phenobarbital; Respiration, Artificial; Systematic Reviews as Topic

2023

Trials

3 trial(s) available for ibuprofen and midazolam

ArticleYear
Sedation with midazolam leads to reduced pain after dental surgery.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:5

    Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Endpoint Determination; Female; Humans; Hypnotics and Sedatives; Ibuprofen; Male; Midazolam; Molar, Third; Oral Surgical Procedures; Pain Measurement; Pain, Postoperative; Preanesthetic Medication; Single-Blind Method

2004
Pain management in young children undergoing diagnostic tympanocentesis.
    Clinical pediatrics, 2011, Volume: 50, Issue:3

    Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Biopsy, Fine-Needle; Child, Preschool; Codeine; Diagnostic Techniques, Otological; Drug Administration Schedule; Drug Therapy, Combination; Ear, Middle; Female; Humans; Hypnotics and Sedatives; Ibuprofen; Infant; Male; Midazolam; Otitis Media; Pain; Pain Measurement; Treatment Outcome; Tympanic Membrane

2011
Preterm Physiologically Based Pharmacokinetic Model. Part II: Applications of the Model to Predict Drug Pharmacokinetics in the Preterm Population.
    Clinical pharmacokinetics, 2020, Volume: 59, Issue:4

    Topics: Administration, Intravenous; Administration, Oral; Alfentanil; Anti-Bacterial Agents; Caffeine; Computer Simulation; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Female; Gentamicins; Gestational Age; Humans; Hypnotics and Sedatives; Ibuprofen; Infant, Newborn; Kidney; Liver; Male; Metabolic Clearance Rate; Midazolam; Models, Biological; Narcotics; Predictive Value of Tests; Premature Birth; Vancomycin

2020

Other Studies

17 other study(ies) available for ibuprofen and midazolam

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
    Contraception, 2006, Volume: 74, Issue:5

    Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Midazolam; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Regression Analysis

2006
Interdisciplinary approach to endodontic therapy for uncooperative children in a dental school environment.
    Journal of dental education, 2006, Volume: 70, Issue:12

    Topics: Anesthesia, Dental; Anesthetics, Combined; Child; Child Behavior; Chloral Hydrate; Conscious Sedation; Dental Care for Children; Endodontics; Female; Humans; Hydroxyzine; Hypnotics and Sedatives; Ibuprofen; Male; Meperidine; Midazolam; Patient Care Team; Pediatric Dentistry; Retrospective Studies; Root Canal Therapy; Schools, Dental

2006
Precision criteria to derive sample size when designing pediatric pharmacokinetic studies: which measure of variability should be used?
    Journal of clinical pharmacology, 2014, Volume: 54, Issue:3

    Topics: Adult; Area Under Curve; Biomedical Research; Caffeine; Child; Child, Preschool; Female; Humans; Ibuprofen; Infant; Infant, Newborn; Itraconazole; Male; Midazolam; Models, Biological; Pharmacokinetics; Sample Size; Theophylline

2014
Analgesia protocols for burns dressings: Challenges with implementation.
    Burns : journal of the International Society for Burn Injuries, 2019, Volume: 45, Issue:7

    Topics: Academic Medical Centers; Acetaminophen; Analgesics; Anesthetics, Inhalation; Bandages; Burns; Child; Clinical Competence; Fentanyl; Guideline Adherence; Hospitals, Community; Humans; Hypnotics and Sedatives; Ibuprofen; Ketamine; Methoxyflurane; Midazolam; Morphine; Pain Management; Pain Measurement; Pain, Procedural; Practice Guidelines as Topic; Practice Patterns, Physicians'; South Africa; Tertiary Care Centers; Tramadol

2019