ibuprofen and metoprolol

ibuprofen has been researched along with metoprolol in 39 studies

Research

Studies (39)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	20 (51.28)	29.6817
2010's	18 (46.15)	24.3611
2020's	1 (2.56)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Faller, B; Wohnsland, F	1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Caron, G; Ermondi, G	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R	1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Avdeef, A; Tam, KY	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Akamatsu, M	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Evers, S; Gerber, WD; Naumann, E; Pothmann, R; Uberall, M	1
Brosi, K; Croissant, B; Hermann, D; Mann, K	1
Dokoumetzidis, A; Macheras, P; Papadopoulou, V	1
Le Brun, V; Siepmann, F; Siepmann, J	1
Gutkowski, W; Janion, M; Sielski, J; Stepień, A	1
Cosijns, A; De Beer, T; Evrard, B; Nikolakakis, I; Nizet, D; Remon, JP; Siepmann, F; Siepmann, J; Vervaet, C	1
Peuravuori, J; Pihlaja, K	1
Heikkinen, AT; Korjamo, T; Mönkkönen, J	1
Kunkel, U; Radke, M; Riml, J; Wörman, A	1
Cornelius, G; Dixon, G; Fancher, RM; Ford, K; Foster, KA; Gudmundsson, OS; Hageman, MJ; Proszynski, M; Sun, H	1
Butkovskyi, A; Hernandez Leal, L; Meulepas, RJW; Rijnaarts, HHM; Sevenou, L; Zeeman, G	1
Lowinger, MB; Ormes, JD; Small, JH; Su, Y; Williams, RO; Zhang, F	1
Bouwman, H; Kümmerer, K; Kylin, H; Nantaba, F; Palm, WU; Wasswa, J	1

Reviews

2 review(s) available for ibuprofen and metoprolol

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Treatment of idiopathic headache in childhood - recommendations of the German Migraine and Headache Society (DMKG)]. Schmerz (Berlin, Germany), 2002, Volume: 16, Issue:1 Topics: Acetaminophen; Adrenergic beta-Antagonists; Age Factors; Analgesics, Non-Narcotic; Biofeedback, Psychology; Child; Flunarizine; GABA Agents; Headache; Humans; Ibuprofen; Metoprolol; Migraine Disorders; Practice Guidelines as Topic; Propranolol; Relaxation Therapy; Serotonin Receptor Agonists; Sumatriptan; Tension-Type Headache; Valproic Acid; Vasodilator Agents	2002

Article

Year

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Drug discovery today, 2016, Volume: 21, Issue:4

Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

[Treatment of idiopathic headache in childhood - recommendations of the German Migraine and Headache Society (DMKG)].

Schmerz (Berlin, Germany), 2002, Volume: 16, Issue:1

Topics: Acetaminophen; Adrenergic beta-Antagonists; Age Factors; Analgesics, Non-Narcotic; Biofeedback, Psychology; Child; Flunarizine; GABA Agents; Headache; Humans; Ibuprofen; Metoprolol; Migraine Disorders; Practice Guidelines as Topic; Propranolol; Relaxation Therapy; Serotonin Receptor Agonists; Sumatriptan; Tension-Type Headache; Valproic Acid; Vasodilator Agents

2002

Other Studies

37 other study(ies) available for ibuprofen and metoprolol

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes. Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6 Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water	2001
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
QSAR study on permeability of hydrophobic compounds with artificial membranes. Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11 Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship	2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability? Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Importance of physicochemical properties for the design of new pesticides. Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7 Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests	2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
[Drug-induced headache and pain reduction medication with amitriptyline in an 11-year old pupil]. Der Nervenarzt, 2004, Volume: 75, Issue:5 Topics: Amitriptyline; Analgesics; Antihypertensive Agents; Aspirin; Child; Dipyrone; Headache Disorders; Humans; Ibuprofen; Male; Metoprolol; Migraine Disorders; Students; Treatment Outcome	2004
Analysis of dissolution data using modified versions of Noyes-Whitney equation and the Weibull function. Pharmaceutical research, 2006, Volume: 23, Issue:2 Topics: Adrenergic beta-Antagonists; Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Ibuprofen; Metoprolol; Models, Statistical; Pharmaceutical Preparations; Solubility	2006
Drugs acting as plasticizers in polymeric systems: a quantitative treatment. Journal of controlled release : official journal of the Controlled Release Society, 2006, Oct-27, Volume: 115, Issue:3 Topics: Chemistry, Pharmaceutical; Chlorpheniramine; Delayed-Action Preparations; Diffusion; Drug Carriers; Ibuprofen; Kinetics; Metoprolol; Models, Chemical; Plasticizers; Polymethacrylic Acids; Solubility; Tensile Strength; Transition Temperature	2006
Is the intra-aortic balloon pump a method of brain protection during cardiogenic shock after drug intoxication? The Journal of emergency medicine, 2010, Volume: 38, Issue:2 Topics: Adolescent; Adrenergic beta-Antagonists; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Brain Diseases; Calcium Channel Blockers; Female; Humans; Ibuprofen; Intra-Aortic Balloon Pumping; Metoprolol; Shock, Cardiogenic; Suicide, Attempted; Verapamil	2010
Porous pellets as drug delivery system. Drug development and industrial pharmacy, 2009, Volume: 35, Issue:6 Topics: Acetaminophen; Cellulose; Chemistry, Pharmaceutical; Drug Delivery Systems; Excipients; Ibuprofen; Metoprolol; Porosity; Sodium Chloride; Spectrum Analysis, Raman	2009
Phototransformations of selected pharmaceuticals under low-energy UVA-vis and powerful UVB-UVA irradiations in aqueous solutions--the role of natural dissolved organic chromophoric material. Analytical and bioanalytical chemistry, 2009, Volume: 394, Issue:6 Topics: Carbamazepine; Ibuprofen; Kinetics; Metoprolol; Molecular Structure; Molecular Weight; Nitrates; Photochemical Processes; Solid Phase Extraction; Solubility; Solutions; Ultraviolet Rays; Warfarin	2009
Determination of permeation resistance distribution in in vitro cell monolayer permeation experiments. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2010, May-12, Volume: 40, Issue:2 Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Caco-2 Cells; Cell Culture Techniques; Cell Membrane Permeability; Humans; Hydrogen-Ion Concentration; Ibuprofen; Metoprolol; Models, Biological; Propranolol	2010
Evaluating the fate of six common pharmaceuticals using a reactive transport model: insights from a stream tracer test. The Science of the total environment, 2013, Aug-01, Volume: 458-460 Topics: Adsorption; Bezafibrate; Chromatography, High Pressure Liquid; Clofibric Acid; Ibuprofen; Metoprolol; Models, Theoretical; Naproxen; Pharmaceutical Preparations; Rivers; Sensitivity and Specificity; Sweden; Tandem Mass Spectrometry; Water Movements; Water Pollutants, Chemical	2013
Utility of gastric-retained alginate gels to modulate pharmacokinetic profiles in rats. Journal of pharmaceutical sciences, 2013, Volume: 102, Issue:8 Topics: Administration, Oral; Alginates; Animals; Antihypertensive Agents; Celecoxib; Cyclooxygenase Inhibitors; Delayed-Action Preparations; Gastric Mucosa; Gels; Glucuronic Acid; Hexuronic Acids; Ibuprofen; Male; Metoprolol; Permeability; Pyrazoles; Rats; Rats, Sprague-Dawley; Solubility; Sulfonamides	2013
Micropollutant removal from black water and grey water sludge in a UASB-GAC reactor. Water science and technology : a journal of the International Association on Water Pollution Research, 2018, Volume: 77, Issue:3-4 Topics: Anaerobiosis; Benzopyrans; Bioreactors; Carbon; Diclofenac; Ibuprofen; Metoprolol; Sewage; Triclosan; Waste Disposal, Fluid; Water Pollutants, Chemical	2018
How broadly can poly(urethane)-based implants be applied to drugs of varied properties? International journal of pharmaceutics, 2019, Sep-10, Volume: 568 Topics: Dextrans; Diffusion; Drug Implants; Emtricitabine; Fluorescein-5-isothiocyanate; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Membranes, Artificial; Metoprolol; Molecular Weight; Permeability; Polyurethanes; Porosity	2019
Spatial trends and ecotoxic risk assessment of selected pharmaceuticals in sediments from Lake Victoria, Uganda, East Africa. The Science of the total environment, 2024, Jan-01, Volume: 906 Topics: Anti-Bacterial Agents; Ciprofloxacin; Ecosystem; Environmental Monitoring; Ibuprofen; Lakes; Levofloxacin; Metoprolol; Pharmaceutical Preparations; Risk Assessment; Uganda; Water Pollutants, Chemical	2024