ibuprofen and metoclopramide

ibuprofen has been researched along with metoclopramide in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.55)18.2507
2000's11 (50.00)29.6817
2010's9 (40.91)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
DeHart, DA; Delaney, J; Ellis, GL; Owens, A1
Acharya, MR; Conley, BA; Doroshow, JH; Figg, WD; Sausville, EA; Sparreboom, A; Venitz, J1
Boey, FY; Tang, YD; Venkatraman, SS; Wang, LW1
Gattani, S; Shiyani, B; Surana, S1
Lee, WL; Loei, C; Loo, SC; Widjaja, E1
Dragoman, MV; Dung, DL; Grossman, D; Habib, N; Huong, NM; Kapp, N; Tamang, A1
Bhai, SF; Gregorie, WD; Harris, NS; Irons, HR; Salas, RN1

Reviews

1 review(s) available for ibuprofen and metoclopramide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for ibuprofen and metoclopramide

ArticleYear
The efficacy of metoclopramide in the treatment of migraine headache.
    Annals of emergency medicine, 1993, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Humans; Ibuprofen; Metoclopramide; Migraine Disorders; Treatment Outcome

1993
Two prophylactic medication approaches in addition to a pain control regimen for early medical abortion < 63 days' gestation with mifepristone and misoprostol: study protocol for a randomized, controlled trial.
    Reproductive health, 2016, Oct-12, Volume: 13, Issue:1

    Topics: Abortifacient Agents, Nonsteroidal; Abortifacient Agents, Steroidal; Abortion, Induced; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Antiemetics; Clinical Protocols; Double-Blind Method; Drug Administration Schedule; Female; Humans; Ibuprofen; Metoclopramide; Mifepristone; Misoprostol; Pain; Pain Management; Postoperative Nausea and Vomiting; Pregnancy; Research Design; Tramadol; Young Adult

2016
Prospective Double-Blinded Randomized Field-Based Clinical Trial of Metoclopramide and Ibuprofen for the Treatment of High Altitude Headache and Acute Mountain Sickness.
    Wilderness & environmental medicine, 2020, Volume: 31, Issue:1

    Topics: Adult; Altitude Sickness; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Cyclooxygenase Inhibitors; Dopamine D2 Receptor Antagonists; Double-Blind Method; Female; Headache; Humans; Ibuprofen; Male; Metoclopramide; Middle Aged; Mountaineering; Nepal; Prospective Studies; Treatment Outcome; Young Adult

2020

Other Studies

18 other study(ies) available for ibuprofen and metoclopramide

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
[More than six billions Euro costs due to illness days. Migraine therapy counts].
    MMW Fortschritte der Medizin, 2003, May-26, Volume: 145 Suppl 2

    Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Aspirin; Cost of Illness; Costs and Cost Analysis; Domperidone; Dopamine Antagonists; Drug Therapy, Combination; Germany; Humans; Ibuprofen; Metoclopramide; Migraine Disorders; Serotonin Receptor Agonists; Sick Leave

2003
Interspecies differences in plasma protein binding of MS-275, a novel histone deacetylase inhibitor.
    Cancer chemotherapy and pharmacology, 2006, Volume: 57, Issue:3

    Topics: Animals; Area Under Curve; Benzamides; Binding, Competitive; Blood Proteins; Dogs; Glycoproteins; Half-Life; Histone Deacetylase Inhibitors; Humans; Ibuprofen; Metoclopramide; Mice; Neoplasms; Orosomucoid; Protein Binding; Pyridines; Rabbits; Rats; Serum Albumin; Species Specificity; Swine; Time Factors

2006
Sustained release of hydrophobic and hydrophilic drugs from a floating dosage form.
    International journal of pharmaceutics, 2007, May-04, Volume: 336, Issue:1

    Topics: Alginates; Delayed-Action Preparations; Gastric Juice; Gels; Glucuronic Acid; Hexuronic Acids; Ibuprofen; Metoclopramide; Microscopy, Electron, Scanning; Niacinamide; Particle Size; Plant Oils; Polymethacrylic Acids; Polyvinyl Alcohol; Sunflower Oil; Water

2007
Formulation and evaluation of bi-layer tablet of metoclopramide hydrochloride and ibuprofen.
    AAPS PharmSciTech, 2008, Volume: 9, Issue:3

    Topics: Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Combinations; Drug Evaluation, Preclinical; Ibuprofen; Metoclopramide; Tablets

2008
Altering the drug release profiles of double-layered ternary-phase microparticles.
    Journal of controlled release : official journal of the Controlled Release Society, 2011, May-10, Volume: 151, Issue:3

    Topics: Chromatography, Gel; Drug Carriers; Drug Compounding; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Lactic Acid; Metoclopramide; Microscopy, Electron, Scanning; Molecular Weight; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility; Spectrum Analysis, Raman; Surface Properties

2011