ibuprofen has been researched along with methotrexate in 46 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (13.04) | 18.7374 |
1990's | 8 (17.39) | 18.2507 |
2000's | 17 (36.96) | 29.6817 |
2010's | 15 (32.61) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Andrews, PR; Craik, DJ; Martin, JL | 1 |
Topliss, JG; Yoshida, F | 1 |
Faller, B; Wohnsland, F | 1 |
Cha, SH; Endou, H; Fukushima , JI; Goya, T; Kanai, Y; Kobayashi, Y; Sekine, T | 1 |
Cha, SH; Endou, H; Hosoyamada, M; Khamdang, S; Kimura, H; Narikawa, S; Sekine, T; Takeda, M | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
Eraly, SA; Kaler, G; Khandelwal, A; Nagle, M; Nigam, SK; Swaan, PW; Truong, DM | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Kitchen, EA; Meacock, SC | 1 |
Bradley, JD; Brater, DC; Hall, SD; Jones, DR; Krohn, K; Tracy, TS | 1 |
Calin, A; Elswood, J | 1 |
Coates, J; Friedman, H; Jamali, F; Russell, AS; Skeith, KJ | 1 |
Campbell, JR; Maloley, PA; Montgomery, HA; Nelson, E | 1 |
Carmichael, AJ; Ryatt, KS | 1 |
Cassano, WF | 1 |
Constable, TJ; Ryatt, KS; Wallis, PJ | 1 |
Jaffe, IA | 1 |
Fraunfelder, FT | 1 |
Creinin, MD | 1 |
Connolly, KM; Noel, LS; Smith-Oliver, T; Stimpson, SS; Yarnall, DP | 1 |
Lewinski, UH; Schifter, T | 1 |
Murray, KJ; Nistala, K | 1 |
Balabanova, RM | 1 |
Cimmino, MA; Garlaschi, G; Parodi, M; Silvestri, E | 1 |
Akiyoshi, K; Izumi, T; Kawano, T; Korematsu, S; Maeda, T; Miyahara, H; Sato, K; Suenobu, S; Yamada, H | 1 |
Hoshika, A; Kawashima, H; Nagao, R; Sato, S; Suzuki, K; Tsuyuki, K | 1 |
Ash, Z; Aydin, SZ; Del Galdo, F; Emery, P; Marzo-Ortega, H; McGonagle, D; Wakefield, RJ | 1 |
Dilek, E; Polat, MF | 1 |
3 review(s) available for ibuprofen and methotrexate
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Current concepts of pharmacotherapy in rheumatoid arthritis].
Topics: Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cyclooxygenase Inhibitors; Cyclophosphamide; Cyclosporine; Double-Blind Method; Drug Therapy, Combination; Feasibility Studies; Female; Glucocorticoids; Humans; Ibuprofen; Immunosuppressive Agents; Isoxazoles; Ketoprofen; Leflunomide; Male; Methotrexate; Prednisolone; Prognosis; Randomized Controlled Trials as Topic; Risk Factors; Sulfasalazine; Time Factors | 2003 |
Optical coherence tomography: a new tool to assess nail disease in psoriasis?
Topics: Aged; Arthritis, Psoriatic; Dermatologic Agents; Female; Humans; Ibuprofen; Methotrexate; Nail Diseases; Tomography, Optical Coherence; Ultrasonography | 2011 |
1 trial(s) available for ibuprofen and methotrexate
Article | Year |
---|---|
Methotrexate and misoprostol for abortion at 57-63 days gestation.
Topics: Abortion, Induced; Acetaminophen; Administration, Oral; Adult; Chorionic Gonadotropin; Codeine; Colic; Drug Therapy, Combination; Female; Humans; Ibuprofen; Injections, Intramuscular; Methotrexate; Mifepristone; Misoprostol; Pilot Projects; Pregnancy; Pregnancy Trimester, First; Time Factors | 1994 |
42 other study(ies) available for ibuprofen and methotrexate
Article | Year |
---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water | 2001 |
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; Gene Library; Humans; Kidney Tubules, Proximal; Molecular Sequence Data; Oocytes; Organic Anion Transporters, Sodium-Independent; Sequence Homology, Amino Acid; Tissue Distribution; Transfection; Xenopus laevis | 2001 |
Characterization of methotrexate transport and its drug interactions with human organic anion transporters.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cells, Cultured; Humans; Indomethacin; Kinetics; Liver-Specific Organic Anion Transporter 1; Methotrexate; Mice; Mice, Transgenic; Nerve Tissue Proteins; Organic Anion Transporters, Sodium-Independent; Phenylbutazone; Potassium Channels; Potassium Channels, Tandem Pore Domain; Probenecid | 2002 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members.
Topics: Binding Sites; Hydrophobic and Hydrophilic Interactions; Kinetics; Molecular Structure; Organic Anion Transport Protein 1; Organic Anion Transporters; Static Electricity; Substrate Specificity | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Some effects of non-steroidal anti-inflammatory drugs on leucocyte migration.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Cell Movement; Edema; Fenoprofen; Ibuprofen; Indomethacin; Ketoprofen; Leukocytes; Male; Methotrexate; Naproxen; Phenylbutazone; Pleurisy; Rats | 1976 |
The effects of a salicylate, ibuprofen, and naproxen on the disposition of methotrexate in patients with rheumatoid arthritis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Blood Proteins; Choline; Female; Humans; Ibuprofen; Kidney; Male; Metabolic Clearance Rate; Methotrexate; Middle Aged; Naproxen; Protein Binding; Salicylates | 1992 |
A prospective nationwide cross-sectional study of NSAID usage in 1331 patients with ankylosing spondylitis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cross-Sectional Studies; Diclofenac; Female; Gold; Humans; Ibuprofen; Male; Methotrexate; Middle Aged; Naproxen; Penicillamine; Piroxicam; Prednisolone; Prospective Studies; Spondylitis, Ankylosing; Sulfasalazine; United Kingdom | 1990 |
Lack of significant interaction between low dose methotrexate and ibuprofen or flurbiprofen in patients with arthritis.
Topics: Administration, Oral; Aged; Arthritis, Rheumatoid; Drug Interactions; Female; Flurbiprofen; Humans; Ibuprofen; Injections, Intramuscular; Male; Methotrexate; Middle Aged | 1990 |
Severe reversible thrombocytopenia resulting from butoconazole cream.
Topics: Administration, Intravaginal; Antifungal Agents; Female; Humans; Ibuprofen; Imidazoles; Methotrexate; Middle Aged; Ointments; Thrombocytopenia | 1990 |
Pneumocystis carinii pneumonia following methotrexate.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Lymphopenia; Methotrexate; Pneumonia, Pneumocystis | 1990 |
Serious methotrexate toxicity caused by interaction with ibuprofen.
Topics: Adolescent; Drug Interactions; Humans; Ibuprofen; Male; Methotrexate | 1989 |
Pneumocystis carinii pneumonia complicating low dose methotrexate treatment for psoriatic arthropathy.
Topics: Adolescent; Arthritis; Drug Synergism; Drug Therapy, Combination; Female; Humans; Ibuprofen; Immunosuppression Therapy; Methotrexate; Pneumonia, Pneumocystis; Psoriasis | 1989 |
On the treatment of rheumatoid arthritis with M&Ms (Motrin & methotrexate)
Topics: Arthritis, Rheumatoid; Drug Therapy, Combination; Humans; Ibuprofen; Methotrexate | 1988 |
Interim report: National Registry of possible Drug-induced Ocular Side Effects.
Topics: Contact Lenses; Drug-Related Side Effects and Adverse Reactions; Eye Diseases; Fluorouracil; Humans; Ibuprofen; Methotrexate; Neomycin; Practolol; Registries; Sterilization; Tamoxifen; Timolol; United States; United States Food and Drug Administration | 1980 |
Elevated levels of TNF in the joints of adjuvant arthritic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Biological Assay; Cells, Cultured; Cyclosporine; Edema; Freund's Adjuvant; Ibuprofen; Isoxazoles; Joints; L Cells; Leflunomide; Macrophages, Peritoneal; Male; Methotrexate; Mice; Mycobacterium tuberculosis; Rabbits; Rats; Rats, Inbred Lew; Tumor Necrosis Factor-alpha | 1993 |
Adult onset Still's disease associated with Epstein-Barr virus infection in a 66-year-old woman.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Antinuclear; Antirheumatic Agents; Arthralgia; Blood Sedimentation; Female; Ferritins; Fever; Herpesviridae Infections; Herpesvirus 4, Human; Humans; Ibuprofen; Methotrexate; Middle Aged; Rheumatoid Factor; Still's Disease, Adult-Onset; Tumor Virus Infections | 1998 |
Co-existent sickle cell disease and juvenile rheumatoid arthritis. Two cases with delayed diagnosis and severe destructive arthropathy.
Topics: Adolescent; Anemia, Sickle Cell; Arthritis, Juvenile; Disease Progression; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Ibuprofen; Magnetic Resonance Imaging; Methotrexate; Physical Therapy Modalities; Risk Assessment; Severity of Illness Index; Time Factors | 2001 |
Magnetic resonance imaging in the differential diagnosis between polymyalgia rheumatica and elderly onset rheumatoid arthritis.
Topics: Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Diagnosis, Differential; Diagnostic Errors; Glucocorticoids; Hand; Hand Joints; Humans; Ibuprofen; Magnetic Resonance Imaging; Male; Methotrexate; Methylprednisolone; Polymyalgia Rheumatica; Prednisolone; Radiography; Treatment Outcome | 2006 |
A relapse of systemic type juvenile idiopathic arthritis after a rubella vaccination in a patient during a long-term remission period.
Topics: Arthritis, Juvenile; Child; Female; Heart Failure; Humans; Ibuprofen; Methotrexate; Recurrence; Rubella Vaccine; Vaccination; Vaccines, Attenuated | 2009 |
A case of juvenile idiopathic polyarticular arthritis complicated by IgA deficiency in 22q11 deletion syndrome.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Juvenile; Child; Chromosome Deletion; Chromosomes, Human, Pair 22; Drug Therapy, Combination; Female; Humans; Ibuprofen; IgA Deficiency; Methotrexate; Synovitis | 2011 |
In Vitro Inhibition Of Three Different Drugs Used In Rheumatoid Arthritis Treatment On Human Serum Paraoxanase 1 Enzyme Activity.
Topics: Antirheumatic Agents; Aryldialkylphosphatase; Catalytic Domain; Dose-Response Relationship, Drug; Humans; Ibuprofen; In Vitro Techniques; Meloxicam; Methotrexate; Thiazines; Thiazoles | 2016 |