ibuprofen has been researched along with mefenamic acid in 94 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 37 (39.36) | 18.7374 |
1990's | 10 (10.64) | 18.2507 |
2000's | 13 (13.83) | 29.6817 |
2010's | 27 (28.72) | 24.3611 |
2020's | 7 (7.45) | 2.80 |
Authors | Studies |
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Huang, LJ; Kuo, SC; Nakamura, H | 1 |
Chang, TK; Ensom, MH; Kiang, TK | 1 |
Bain, G; Beher, D; Chen, W; Jiang, X; Munoz, B; Peachey, J; Prasit, P; Shearman, MS; St-Jacques, R; Stock, N; Williamson, TL; Wrigley, JD | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Haque, N; Molvi, KI; Sudarsanam, V; Vasu, KK; Yerande, SG | 1 |
Abdel-Azeem, AZ; Abdel-Hafez, AA; El-Karamany, GS; Farag, HH | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T | 1 |
Kumar, M; Sinha, VR; Thareja, S | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
Bellman, K; Knegtel, RM; Settimo, L | 1 |
Kourounakis, PN; Kourti, M; Rekka, EA; Theodosis-Nobelos, P; Tziona, P | 1 |
Bennis, K; Ducki, S; Lesage, F; Vivier, D | 1 |
Gavalas, A; Kourti, M; Rekka, EA; Theodosis-Nobelos, P | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
Kalgutkar, AS | 1 |
DeRose, EF; Duff, MR; Gabel, SA; Howell, EE; Krahn, JM; London, RE; Pedersen, LC | 1 |
Anderson, JA; Buchanan, WW; Lee, P; Miller, J; Webb, J | 1 |
Huskisson, EC | 1 |
Cavalli-Björkman, K; Jacobson, J; Lundström, V; Nilsson, B; Norbeck, M | 1 |
Hart, FD | 1 |
Leslie, RD | 1 |
Adkinson, NF; Kordansky, D; Norman, PS; Rosenthal, RR | 1 |
Baranova, EIa; Dormidontov, EN; Korshunov, NI | 1 |
Brooks, PM | 1 |
Muirden, KD; Stockman, A; Varigos, GA | 1 |
Lands, WE; Rome, LH | 1 |
Shearman, RP; Smith, ID; Temple, DM | 1 |
Motohashi, M; Yamashita, K; Yashiki, T | 1 |
Raineri-Gerber, I; von Felten, A | 1 |
Wallenstein, MC | 4 |
Breckwoldt, M; Zahradnik, HP | 1 |
Barnard-Jones, K; Davies, RW; Lalla, O; Mann, PG; Welch, RB | 1 |
Penning, TM; Smithgall, TE | 1 |
Ciancio, SG | 1 |
Keat, AC; Keat, EC; Ravi, S | 1 |
Seymour, RA | 1 |
Iizuka, Y; Tanaka, K | 1 |
Prescott, LF | 1 |
Powell, JR; Smith, RP | 1 |
Melvin, JR; Osyamkpe, CO; Sanfilippo, JS; Teichman, J; Wittliff, JL | 1 |
Owen, PR | 1 |
Amadio, P | 1 |
Court, H; Volans, GN | 1 |
Deuben, RR | 1 |
Halbert, DR | 1 |
Fraser, IS | 1 |
Roy, S | 1 |
Gever, LN | 1 |
Cooper, SL | 1 |
Mills, JA; Simon, LS | 1 |
Fudenberg, HH; Jonsson, HT; Smith, CL; Wilson, GB | 1 |
Pedrón Nuevo, DN | 1 |
Duncan, KM; Hart, LL | 1 |
Cahill, RJ; Gilvarry, J; O'Morain, CA; Sant, SM | 1 |
Ghatikar, KN; Keny, S; Khubchandani, RP; Usgaonkar, NG | 1 |
Lownie, JF; Lownie, MA; Reinach, SG | 1 |
Li Wan Po, A; Zhang, WY | 1 |
Curti, C; Mingatto, FE; Pigoso, AA; Rodrigues, T; Santos, AC; Uyemura, SA | 1 |
Bhatnagar, SK; Chandra, J | 1 |
Kaewnopparat, N; Kaewnopparat, S; Kasiwong, S; Phadoongsombut, N; Pinsuwan, S; Rojanasakul, Y; Tantishaiyakul, V; Wiwattanawongsa, K | 1 |
De Alencastro, LF; Grandjean, D; Tarradellas, J; Tauxe-Wuersch, A | 1 |
Jones, OA; Lester, JN; Voulvoulis, N | 1 |
Atherton, J; Bauman, J; Kohl, C; Lam, W; Lou, Z; Mutlib, A; Reily, M; Walker, GS | 1 |
Nogueira, JM; Portugal, FC; Silva, AR | 1 |
Goli, M; Moattar, F; Ozgoli, G | 1 |
Duggan, KC; Marnett, LJ; Prusakiewicz, JJ; Rouzer, CA | 1 |
Ali, HI; Hegazy, GH | 1 |
Chai, MZ; Flanagan, JU; Squire, CJ; Teague, RM; Turnbull, AP; Yosaatmadja, Y | 1 |
Abedi, H; Ebrahimzadeh, H | 1 |
Krajewska, J; Laudy, AE; Mrowka, A; Tyski, S | 1 |
Abubakr, NH; Elzaki, WM; Ibrahim, YE; Ziada, HM | 1 |
Choo, YW; Fernández, C; Lim, SH; Mariño, EL; Modamio, P; Ooi, IH; Segarra, I; Tan, SY; Tiew, AL; Wong, MM | 1 |
Cooper, G; Crichton, S; Eddleston, M; Kamour, A; Lupton, DJ; Thomas, SH; Thompson, JP; Vale, JA | 1 |
Chan, EWL; Raja, I; Yap, JKY; Yee, ZY | 1 |
Arghavani-Beydokhti, S; Asghari, A; Rajabi, M | 1 |
Chang, CH; Dong, YH; Hwang, JS; Toh, S; Wu, LC | 1 |
Chang, CC; Chen, YR; Chi, NF; Chiou, HY; Hsieh, FI; Wu, HC | 1 |
Sanàti, SE; Seidi, S | 1 |
Escobedo-Hinojosa, W; Hauer, B; Klenk, JM; Kontny, LH; Nebel, BA | 1 |
Abed, A; Abu-Shalhoob, M; Jarrar, Q; Jarrar, Y; Sha'ban, E | 1 |
Hadjmohammadi, MR; Jafari, Z | 1 |
Darvishnejad, F; Ghani, M; Raoof, JB | 1 |
Ding, F; Gao, M; Han, T; Mao, S; Shen, T; Zhao, Q | 1 |
Ikushiro, S; Iwai, Y; Nishikawa, M; Sakaki, T; Sugimoto, H; Takita, T; Yasuda, K; Yasukawa, K; Yogo, Y | 1 |
Christelle, K; Jaafar, SH; Norhayati, MN | 1 |
9 review(s) available for ibuprofen and mefenamic acid
Article | Year |
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UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship | 2016 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Antiinflammatory drugs.
Topics: Adult; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Benzylidene Compounds; Child; Drug Evaluation; Female; Humans; Ibuprofen; Indenes; Indomethacin; Ketoprofen; Mefenamic Acid; Naproxen; Phenylacetates; Phenylbutazone; Pregnancy; Pregnancy Complications; Propionates; Tolmetin | 1977 |
Nonsteroidal antiinflammatory drugs (second of two parts).
Topics: Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Fenoprofen; Humans; Ibuprofen; Mefenamic Acid; Naproxen; Propionates; Sulindac; Tolmetin | 1980 |
Nonsteroidal antiinflammatory drugs in menorrhagia.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Danazol; Female; Humans; Ibuprofen; Mefenamic Acid; Menorrhagia; Naproxen | 1993 |
Efficacy of minor analgesics in primary dysmenorrhoea: a systematic review.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dysmenorrhea; Female; Humans; Ibuprofen; Mefenamic Acid; Middle Aged; Naproxen; Randomized Controlled Trials as Topic | 1998 |
Antipyretics in children.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Child; Cyclooxygenase Inhibitors; Fever; Humans; Ibuprofen; Mefenamic Acid; Sulfonamides | 2002 |
Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine-device use.
Topics: Acetaminophen; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Dysmenorrhea; Female; Humans; Ibuprofen; Intrauterine Devices, Medicated; Mefenamic Acid; Menorrhagia; Middle Aged; Naproxen; Thiamine; Tranexamic Acid; Young Adult | 2022 |
13 trial(s) available for ibuprofen and mefenamic acid
Article | Year |
---|---|
Evaluation of analgesic action and efficacy of antirheumatic drugs. Study of 10 drugs in 684 patients with rheumatoid arthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Flurbiprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Mefenamic Acid; Pain; Phenylacetates; Placebos; Prednisone; Salicylates | 1976 |
Prostaglandin synthetase inhibitors and dysmenorrhea. A survey and personal clinical experience.
Topics: Adolescent; Adult; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Evaluation; Dysmenorrhea; Female; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Naproxen; ortho-Aminobenzoates; Placebos; Prostaglandin Antagonists | 1979 |
Mefenamic acid compared with ibuprofen in the treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Humans; Ibuprofen; Male; Mefenamic Acid; Middle Aged; Phenylpropionates | 1977 |
Asthma improved by nonsteroidal anti-inflammatory drugs.
Topics: Airway Resistance; Anti-Inflammatory Agents; Aspirin; Asthma; Clinical Trials as Topic; Female; Forced Expiratory Volume; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Middle Aged; Phenylbutazone; Placebos; Respiratory Function Tests; Sodium Salicylate; Spirometry; Tartrazine | 1978 |
Comparison of effectiveness of mefenamic acid and ibuprofen in treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Humans; Ibuprofen; Male; Mefenamic Acid; Phenylpropionates | 1976 |
Mefenamic acid versus ibuprofen in osteoarthritis--a double-blind cross-over study.
Topics: Clinical Trials as Topic; Double-Blind Method; Female; Humans; Ibuprofen; Male; Mefenamic Acid; Osteoarthritis | 1986 |
Mefenamic acid, ibuprofen, and dysmenorrhea.
Topics: Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea; Female; Humans; Ibuprofen; Mefenamic Acid | 1984 |
Prostaglandin synthetase inhibitors in the treatment of primary dysmenorrhea. Outcome trials reviewed.
Topics: Clinical Trials as Topic; Cyclooxygenase Inhibitors; Dysmenorrhea; Female; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Naproxen | 1984 |
[Treatment of primary dysmenorrhea. Comparative study of ibuprofen and mefenamic acid].
Topics: Adolescent; Adult; Double-Blind Method; Dysmenorrhea; Female; Humans; Ibuprofen; Mefenamic Acid; Pain Measurement | 1995 |
Choice of antipyretic in children.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Female; Fever; Humans; Ibuprofen; Infant; Male; Mefenamic Acid; Time Factors | 1995 |
Comparison of the safety and efficacy of a combination analgesic Myprodol and Ponstan in the treatment of dental pain.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Codeine; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Male; Mefenamic Acid; Molar, Third; Pain, Postoperative; Tooth Extraction; Tooth, Impacted; Tooth, Unerupted | 1992 |
Comparison of effects of ginger, mefenamic acid, and ibuprofen on pain in women with primary dysmenorrhea.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Dysmenorrhea; Female; Humans; Ibuprofen; Mefenamic Acid; Patient Satisfaction; Phytotherapy; Plant Preparations; Rhizome; Young Adult; Zingiber officinale | 2009 |
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Lidocaine; Male; Mefenamic Acid; Pain; Pain Measurement; Pain, Postoperative; Placebos; Pulpitis; Root Canal Preparation; Root Canal Therapy | 2016 |
72 other study(ies) available for ibuprofen and mefenamic acid
Article | Year |
---|---|
Studies on heterocyclic compounds. 6. Synthesis and analgesic and antiinflammatory activities of 3,4-dimethylpyrano[2,3-c]pyrazol-6-one derivatives.
Topics: Analgesia; Analgesics; Animals; Anti-Inflammatory Agents; Biological Assay; Female; Indicators and Reagents; Isomerism; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Mice, Inbred Strains; Pyrans; Pyrazoles; Spectrophotometry; Structure-Activity Relationship | 1984 |
The geminal dimethyl analogue of Flurbiprofen as a novel Abeta42 inhibitor and potential Alzheimer's disease modifying agent.
Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cyclooxygenase Inhibitors; Disease Models, Animal; Flurbiprofen; Mice; Peptide Fragments | 2006 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Syntheses of new tetrasubstituted thiophenes as novel anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Rats; Structure-Activity Relationship; Thiophenes | 2007 |
Chlorzoxazone esters of some non-steroidal anti-inflammatory (NSAI) carboxylic acids as mutual prodrugs: design, synthesis, pharmacological investigations and docking studies.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carboxylic Acids; Catalytic Domain; Chlorzoxazone; Computer Simulation; Cyclooxygenase 2; Drug Design; Drug Stability; Esters; Male; Prodrugs; Rats; Rats, Wistar; Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney | 2011 |
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Esters of some non-steroidal anti-inflammatory drugs with cinnamyl alcohol are potent lipoxygenase inhibitors with enhanced anti-inflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cinnamates; Edema; Esters; Glycine max; Hyperlipidemias; Indoleacetic Acids; Lipoxygenase Inhibitors; Polyethylene Glycols; Propanols; Propionates; Rats; Thioctic Acid | 2015 |
Amides of non-steroidal anti-inflammatory drugs with thiomorpholine can yield hypolipidemic agents with improved anti-inflammatory activity.
Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholesterol; Cholesterol, LDL; Edema; Hyperlipidemias; Hypolipidemic Agents; Morpholines; Rats; Triglycerides | 2016 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Designing around Structural Alerts in Drug Discovery.
Topics: Drug Design; Drug Development; Drug Discovery; Drug-Related Side Effects and Adverse Reactions; Humans; Molecular Structure; Pharmaceutical Preparations; Structure-Activity Relationship | 2020 |
The Structural Basis for Nonsteroidal Anti-Inflammatory Drug Inhibition of Human Dihydrofolate Reductase.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Crystallography, X-Ray; Drug Design; Folic Acid; Folic Acid Antagonists; Humans; Models, Molecular; Tetrahydrofolate Dehydrogenase | 2020 |
The new antirheumatic drugs.
Topics: Anti-Inflammatory Agents; Fenoprofen; Flufenamic Acid; Humans; Ibuprofen; Ketoprofen; Mefenamic Acid; Naproxen; Penicillamine; Phenylacetates; Rheumatic Diseases; Salicylates | 1975 |
Drugs for dysmenorrhea.
Topics: Acetaminophen; Aspirin; Dysmenorrhea; Female; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Nalbuphine; Naproxen; Time Factors | 1979 |
[Antirheumatic non-steroid drugs in the treatment of rheumatoid arthritis].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Drug Evaluation; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Phenylbutazone | 1978 |
Nonsteroidal anti-inflammatory drug treatment for arthritis.
Topics: Anti-Inflammatory Agents; Arthritis; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Naproxen; Oxyphenbutazone; Phenylbutazone; Salicylates | 1978 |
Structural requirements for time-dependent inhibition of prostaglandin biosynthesis by anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Fatty Acids; Flurbiprofen; Ibuprofen; Indomethacin; Kinetics; Meclofenamic Acid; Mefenamic Acid; Oxygen Consumption; Oxygenases; Prostaglandins; Structure-Activity Relationship | 1975 |
The antagonism by anti-inflammatory analgesics of prostaglandin f 2 alpha-induced contractions of human and rabbit myometrium in vitro.
Topics: Abortion, Induced; Animals; Anti-Inflammatory Agents; Aspirin; Drug Antagonism; Female; Ibuprofen; Indomethacin; Mefenamic Acid; Myometrium; Phenylbutazone; Pregnancy; Pregnancy Trimester, Second; Prostaglandin Antagonists; Prostaglandins F; Rabbits; Stimulation, Chemical; Uterine Contraction; Uterus | 1975 |
Column-switching techniques for high-performance liquid chromatography of ibuprofen and mefenamic acid in human serum with short-wavelength ultraviolet detection.
Topics: Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Ibuprofen; Mefenamic Acid; Spectrophotometry, Ultraviolet | 1991 |
[Inhibition of thrombocyte function by non-steroidal anti-rheumatic agents: a comparative study between diclofenac, acemetacin, mefenamic acid and ibuprofen].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Cyclooxygenase Inhibitors; Diclofenac; Humans; Ibuprofen; Indomethacin; Malondialdehyde; Mefenamic Acid; Platelet Aggregation; Thromboxanes | 1991 |
Attenuation of epileptogenesis by nonsteroidal anti-inflammatory drugs in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Behavior, Animal; Electrodes; Electroencephalography; Electrophysiology; Epilepsy; Female; Ibuprofen; Mefenamic Acid; Pentylenetetrazole; Rats; Rats, Inbred Strains | 1991 |
[Drug therapy of dysmenorrhea].
Topics: Adrenergic beta-Agonists; Adult; Aspirin; Calcium Channel Blockers; Contraceptives, Oral; Dysmenorrhea; Female; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Magnesium; Mefenamic Acid; Models, Biological; Naproxen; Progestins | 1988 |
Attenuation of penicillin models of epilepsy by nonsteroidal anti-inflammatory drugs.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Brain; Cyclooxygenase Inhibitors; Disease Models, Animal; Epilepsy; Female; Ibuprofen; Mefenamic Acid; Penicillins; Prostaglandins; Rats; Rats, Inbred Strains; Thromboxanes | 1987 |
Inhibition of trans-dihydrodiol oxidation by the non-steroidal anti-inflammatory drugs.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Anti-Inflammatory Agents; Aspirin; Benzopyrenes; Dihydroxydihydrobenzopyrenes; Flufenamic Acid; Ibuprofen; Indomethacin; Liver; Male; Meclofenamic Acid; Mefenamic Acid; Oxidoreductases; Rats; Sulindac; Tolmetin | 1986 |
Drugs in dentistry. NSAIDs.
Topics: Anti-Inflammatory Agents; Dental Care; Diflunisal; Humans; Ibuprofen; Meclofenamic Acid; Mefenamic Acid; Suprofen | 1986 |
Colitis caused by non-steroidal anti-inflammatory drugs.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Female; Flufenamic Acid; Humans; Ibuprofen; Mefenamic Acid; Naproxen; Proctocolitis | 1986 |
Prescribing analgesics.
Topics: Acetaminophen; Aged; Analgesics; Anticoagulants; Aspirin; Child; Codeine; Diflunisal; Drug Hypersensitivity; Female; Humans; Ibuprofen; Mefenamic Acid; Meperidine; Pain, Postoperative; Pentazocine; Pregnancy; Tooth | 1985 |
Differential effects of prostaglandin synthetase inhibitors on EEG in rat.
Topics: Acetaminophen; Animals; Cyclooxygenase Inhibitors; Electroencephalography; Female; Ibuprofen; Indomethacin; Meclofenamic Acid; Mefenamic Acid; Motor Activity; Rats; Rats, Inbred Strains | 1985 |
Differential effect of prostaglandin synthetase inhibitor pretreatment on pentylenetetrazol-induced seizures in rat.
Topics: Acetaminophen; Animals; Behavior, Animal; Cyclooxygenase Inhibitors; Electric Stimulation; Electroencephalography; Female; Hydrogen-Ion Concentration; Ibuprofen; Indomethacin; Meclofenamic Acid; Mefenamic Acid; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures | 1985 |
][A new method for screening of analgesics applied to heat induced inflammatory pain].
Topics: Aminopyrine; Analgesics; Animals; Aspirin; Burns; Drug Evaluation, Preclinical; Flufenamic Acid; Habituation, Psychophysiologic; Hot Temperature; Ibuprofen; Indomethacin; Inflammation; Mefenamic Acid; Phenylbutazone; Pyrroles; Rats | 1974 |
Clinical features and management of analgesic poisoning.
Topics: Acetaminophen; Acetylcysteine; Analgesics; Analgesics, Opioid; Humans; Ibuprofen; Mefenamic Acid; Phenylbutazone; Salicylates | 1984 |
Influence of certain prostaglandin synthetase inhibitors on cytoplasmic estrogen receptors in the uterus.
Topics: Animals; Binding Sites; Cyclooxygenase Inhibitors; Cytoplasm; Female; Ibuprofen; Indomethacin; Mefenamic Acid; Rats; Rats, Inbred Strains; Receptors, Estrogen; Sulindac; Time Factors; Uterus | 1983 |
Peripherally acting analgesics.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Aspirin; Diflunisal; Fenoprofen; Humans; Ibuprofen; Mefenamic Acid; Naproxen; Pain; Primary Health Care | 1984 |
Poisoning after overdose with non-steroidal anti-inflammatory drugs.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Child, Preschool; Diflunisal; Female; Fenoprofen; Feprazone; Humans; Ibuprofen; Indomethacin; Ketoprofen; London; Male; Mefenamic Acid; Naproxen; Oxyphenbutazone; Phenylbutazone; Piroxicam; Thiazines; Tolmetin | 1984 |
Nonopioid analgesics for patients with dental pain.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dental Care; Diflunisal; Humans; Ibuprofen; Kinetics; Mefenamic Acid | 1984 |
Menstrual delay and dysfunctional uterine bleeding associated with antiprostaglandin therapy for dysmenorrhea.
Topics: Adult; Dysmenorrhea; Female; Humans; Ibuprofen; Mefenamic Acid; Menstruation Disturbances; Prostaglandin Antagonists; Uterine Hemorrhage | 1983 |
Dysmenorrhoea: effective new approaches to a controversial problem.
Topics: Cyclooxygenase Inhibitors; Dysmenorrhea; Female; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Naproxen | 1980 |
A double-blind comparison of a propionic acid derivative (ibuprofen) and a fenamate (mefenamic acid) in the treatment of dysmenorrhea.
Topics: Adult; Double-Blind Method; Dysmenorrhea; Female; Humans; Ibuprofen; Mefenamic Acid; Pain | 1983 |
From arthritis pain to dysmenorrhea: a new indication for prostaglandin inhibitors.
Topics: Arthritis; Dysmenorrhea; Female; Humans; Ibuprofen; Mefenamic Acid; Prostaglandin Antagonists | 1980 |
Dysmenorrhea: a new approach to an old problem.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Dysmenorrhea; Female; Humans; Ibuprofen; Mefenamic Acid; Naproxen | 1981 |
Effects of dialyzable leukocyte extracts (DLE) with transfer factor activity on leukocyte migration in vitro. IV. Two distinct effects of DLE on leukocyte migration can be produced by prostaglandins.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Anti-Inflammatory Agents; Antigens; Cell Migration Inhibition; Dialysis; Humans; Ibuprofen; Immunity, Cellular; Indomethacin; Leukocytes; Mefenamic Acid; Molecular Weight; Neutrophils; Prostaglandins; Prostaglandins A; Prostaglandins E; Prostaglandins F; Transfer Factor; Tuberculin | 1980 |
Do non-steroidal anti-inflammatory drugs have an effect on gastric cell turnover?
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Bromodeoxyuridine; Cell Division; Diclofenac; Gastric Mucosa; Gastroscopy; Humans; Ibuprofen; Immunohistochemistry; Indomethacin; Mefenamic Acid; Naproxen; Pyloric Antrum | 1995 |
Influence of nonsteroidal anti-inflammatory drugs on calcium efflux in isolated rat renal cortex mitochondria and aspects of the mechanisms involved.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Cyclosporine; Diclofenac; Dipyrone; Ibuprofen; In Vitro Techniques; Ion Transport; Kidney Cortex; Male; Mefenamic Acid; Mitochondria; NAD; NADP; Oxidation-Reduction; Piroxicam; Rats; Rats, Wistar; Salicylic Acid | 1998 |
Characterization of mefenamic acid-guaiacol ester: stability and transport across Caco-2 cell monolayers.
Topics: Animals; Biological Transport; Caco-2 Cells; Cell Membrane; Drug Stability; Guaiacol; Humans; Ibuprofen; Mefenamic Acid; Swine | 2002 |
Occurrence of several acidic drugs in sewage treatment plants in Switzerland and risk assessment.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Clofibric Acid; Diclofenac; Environmental Monitoring; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Mefenamic Acid; No-Observed-Adverse-Effect Level; Risk Assessment; Sewage; Switzerland; Waste Disposal, Fluid; Water Pollutants, Chemical | 2005 |
The occurrence and removal of selected pharmaceutical compounds in a sewage treatment works utilising activated sludge treatment.
Topics: Acetaminophen; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; England; Environmental Pollutants; Gas Chromatography-Mass Spectrometry; Ibuprofen; Mefenamic Acid; Pharmaceutical Preparations; Propranolol; Sewage; Waste Management | 2007 |
Determination of degradation pathways and kinetics of acyl glucuronides by NMR spectroscopy.
Topics: Acylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile; Chromatography, Liquid; Cyclooxygenase Inhibitors; Diclofenac; Drug Stability; Flufenamic Acid; Glucuronides; Half-Life; Ibuprofen; Indomethacin; Kinetics; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mefenamic Acid; Molecular Structure; Rats; Rats, Sprague-Dawley; Stereoisomerism; Technology, Pharmaceutical; Tolmetin | 2007 |
Advances in stir bar sorptive extraction for the determination of acidic pharmaceuticals in environmental water matrices Comparison between polyurethane and polydimethylsiloxane polymeric phases.
Topics: Chromatography, High Pressure Liquid; Diclofenac; Dimethylpolysiloxanes; Gemfibrozil; Ibuprofen; Mefenamic Acid; Naproxen; Polyurethanes; Reproducibility of Results; Water Pollutants, Chemical; Water Purification | 2008 |
Differential sensitivity and mechanism of inhibition of COX-2 oxygenation of arachidonic acid and 2-arachidonoylglycerol by ibuprofen and mefenamic acid.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Binding, Competitive; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Endocannabinoids; Glycerides; Ibuprofen; Mefenamic Acid; Mice; Oxygen; Protein Binding | 2009 |
Design, synthesis, biological evaluation, and comparative Cox1 and Cox2 docking of p-substituted benzylidenamino phenyl esters of ibuprofenic and mefenamic acids.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Drug Design; Edema; Ibuprofen; Male; Mefenamic Acid; Models, Molecular; Prostaglandin-Endoperoxide Synthases; Protein Binding; Rats; Rats, Wistar; Stomach Ulcer | 2012 |
Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3.
Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anti-Inflammatory Agents, Non-Steroidal; Flufenamic Acid; Flurbiprofen; Hydroxyprostaglandin Dehydrogenases; Ibuprofen; Indomethacin; Meclofenamic Acid; Mefenamic Acid; Naproxen; Sulindac; Tolmetin | 2012 |
Electromembrane-surrounded solid-phase microextraction coupled to ion mobility spectrometry for the determination of nonsteroidal anti-inflammatory drugs: A rapid screening method in complicated matrices.
Topics: Aniline Compounds; Anti-Inflammatory Agents, Non-Steroidal; Electric Conductivity; Electrochemistry; Electrodes; Graphite; Hydrogen-Ion Concentration; Ibuprofen; Limit of Detection; Mass Spectrometry; Mefenamic Acid; Membranes, Artificial; Solid Phase Microextraction; Temperature | 2015 |
The Influence of Efflux Pump Inhibitors on the Activity of Non-Antibiotic NSAIDS against Gram-Negative Rods.
Topics: Acetaminophen; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Escherichia coli; Gram-Negative Bacteria; Ibuprofen; Mefenamic Acid; Microbial Sensitivity Tests; Naproxen | 2016 |
Sunitinib DDI with paracetamol, diclofenac, mefenamic acid and ibuprofen shows sex-divergent effects on the tissue uptake and distribution pattern of sunitinib in mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrier Proteins; Diclofenac; Drug Interactions; Female; Ibuprofen; Indoles; Male; Mefenamic Acid; Mice; Mice, Inbred ICR; Pyrroles; Sex Characteristics; Sunitinib; Tissue Distribution | 2016 |
Central nervous system toxicity of mefenamic acid overdose compared with other NSAIDs: an analysis of cases reported to the United Kingdom National Poisons Information Service.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Diclofenac; Dose-Response Relationship, Drug; Drug Overdose; Female; Humans; Ibuprofen; Infant; Infant, Newborn; Logistic Models; Male; Mefenamic Acid; Middle Aged; Multivariate Analysis; Naproxen; Neurotoxicity Syndromes; Poison Control Centers; Sex Factors; United Kingdom; Young Adult | 2017 |
Synergistic effect of non-steroidal anti-inflammatory drugs (NSAIDs) on antibacterial activity of cefuroxime and chloramphenicol against methicillin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cefuroxime; Chloramphenicol; Diclofenac; Drug Combinations; Drug Interactions; Drug Resistance, Multiple, Bacterial; Drug Synergism; Ibuprofen; Mefenamic Acid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Staphylococcus aureus | 2017 |
Coupling of two centrifugeless ultrasound-assisted dispersive solid/liquid phase microextractions as a highly selective, clean, and efficient method for determination of ultra-trace amounts of non-steroidal anti-inflammatory drugs in complicated matrices.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Hydrogen-Ion Concentration; Hydroxides; Ibuprofen; Limit of Detection; Liquid Phase Microextraction; Mefenamic Acid; Nanotubes, Carbon; Solid Phase Microextraction; Solvents; Ultrasonic Waves; Wastewater | 2018 |
Comparative cardiovascular safety of nonsteroidal anti-inflammatory drugs in patients with hypertension: a population-based cohort study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular System; Celecoxib; Cyclooxygenase 2 Inhibitors; Databases, Pharmaceutical; Diclofenac; Female; Hospitalization; Humans; Hypertension; Ibuprofen; Male; Mefenamic Acid; Middle Aged; Naproxen; Risk Factors | 2018 |
Effect on Risk of Stroke and Acute Myocardial Infarction of Nonselective Nonsteroidal Anti-Inflammatory Drugs in Patients With Rheumatoid Arthritis.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Diclofenac; Female; Humans; Ibuprofen; Logistic Models; Male; Mefenamic Acid; Meloxicam; Middle Aged; Myocardial Infarction; Odds Ratio; Risk Factors; Stroke | 2018 |
Nickel-iron layered double hydroxide nanostructures for micro solid phase extraction of nonsteroidal anti-inflammatory drugs, followed by quantitation by HPLC-UV.
Topics: Adsorption; Alloys; Anti-Inflammatory Agents, Non-Steroidal; Biosensing Techniques; Chromatography, High Pressure Liquid; Diclofenac; Humans; Hydroxides; Ibuprofen; Iron; Limit of Detection; Mefenamic Acid; Metal Nanoparticles; Naproxen; Nickel; Reproducibility of Results; Solid Phase Microextraction; Surface Properties | 2019 |
Oxyfunctionalization of nonsteroidal anti-inflammatory drugs by filamentous-fungi.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Basidiomycota; Cytochrome P-450 Enzyme System; Diclofenac; Fungi; Ibuprofen; Mefenamic Acid; Mucor; Naproxen; Proteomics | 2019 |
Relative Expression of Mouse Udp-glucuronosyl Transferase 2b1 Gene in the Livers, Kidneys, and Hearts: The Influence of Nonsteroidal Anti-inflammatory Drug Treatment.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Glucuronosyltransferase; Ibuprofen; Kidney; Liver; Male; Mefenamic Acid; Meloxicam; Mice, Inbred BALB C; Myocardium | 2019 |
A banana peel/silicon glue coated stir bar for extraction of aspirin, diclofenac, ibuprofen and mefenamic acid followed by high performance liquid chromatography-UV detection.
Topics: Aspirin; Chromatography, High Pressure Liquid; Diclofenac; Humans; Ibuprofen; Mefenamic Acid; Musa; Reproducibility of Results; Silicon; Spectrophotometry, Ultraviolet | 2020 |
In-situ synthesis of nanocubic cobalt oxide @ graphene oxide nanocomposite reinforced hollow fiber-solid phase microextraction for enrichment of non-steroidal anti-inflammatory drugs from human urine prior to their quantification via high-performance liqu
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Cobalt; Diclofenac; Female; Graphite; Humans; Ibuprofen; Limit of Detection; Male; Mefenamic Acid; Nanocomposites; Oxides; Solid Phase Microextraction; Ultraviolet Rays | 2021 |
Efficient removal of mefenamic acid and ibuprofen on organo-Vts with a quinoline-containing gemini surfactant: Adsorption studies and model calculations.
Topics: Adsorption; Ibuprofen; Kinetics; Mefenamic Acid; Quinolines; Spectroscopy, Fourier Transform Infrared; Surface-Active Agents; Water Pollutants, Chemical | 2022 |
Metabolism of non-steroidal anti-inflammatory drugs (NSAIDs) by Streptomyces griseolus CYP105A1 and its variants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bacterial Proteins; Cytochrome P-450 Enzyme System; Diclofenac; Flufenamic Acid; Humans; Ibuprofen; Meclofenamic Acid; Mefenamic Acid; Streptomyces | 2022 |