ibuprofen has been researched along with mannitol in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.23) | 18.7374 |
| 1990's | 1 (3.23) | 18.2507 |
| 2000's | 9 (29.03) | 29.6817 |
| 2010's | 16 (51.61) | 24.3611 |
| 2020's | 4 (12.90) | 2.80 |
| Authors | Studies |
|---|---|
| Duffy, EM; Jorgensen, WL | 1 |
| Faassen, F; Spanings, H; Vogel, G; Vromans, H | 1 |
| Caron, G; Ermondi, G | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Bhatia, G; Khanna, AK; Kumar, M; Modukuri, RK; Rai, S; Sashidhara, KV; Shukla, R; Sonkar, R | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Caplan, M; Hess, ML; Lucchesi, B; Romson, JL; Rowe, GT | 1 |
| Ford, J; Houston, JB; Martin, SW | 1 |
| Candiani, C; Giorgini, A; Mandelli, G; Podda, M; Sacchetta, AC; Selmi, C; Zermiani, P; Zuin, M | 1 |
| Abatzoglou, N; Benedetti, C; Cartilier, L; Léonard, G; McDermott, L; Simard, JS | 1 |
| Pabari, RM; Ramtoola, Z | 1 |
| Busignies, V; Diarra, H; Mazel, V; Tchoreloff, P | 1 |
| Al-Khattawi, A; Alyami, H; Ma, X; Mohammed, AR; Townsend, B | 1 |
| Stebbins, ND; Uhrich, KE; Yu, W | 1 |
| Holm, R; Lagunas, C; Mo, J; Nielsen, CU; Noori, B; Nøhr, MK; Rasmussen, RN | 1 |
| Paul, S; Sun, CC | 1 |
| Afrose, A; George, G; Howes, T; Islam, N; Rashid, A; Rintoul, L; White, ET | 1 |
| Healy, AM; Madi, AM; O'Connell, P; Serrano, DR; Twamley, B; Walsh, D; Worku, ZA | 1 |
| Korhonen, O; Laitinen, R; Ojarinta, R; Saarinen, J; Strachan, CJ | 1 |
| Eda, T; Kagawa, Y; Miyazaki, Y; Uchino, T | 1 |
| Ivone, R; Lin, X; Shen, J; Wang, X; Xie, L; Yang, G; Yang, Y | 1 |
| Berkenkemper, S; Keizer, HL; Kleinebudde, P; Lindenberg, M; Szepes, A | 1 |
| Breitkreutz, J; Kokott, M; Lura, A; Wiedey, R | 1 |
1 review(s) available for ibuprofen and mannitol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for ibuprofen and mannitol
| Article | Year |
|---|---|
Gastrointestinal tolerability of ibuprofen administered in two pharmaceutical formulations.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Female; Gastric Mucosa; Gastrointestinal Diseases; Humans; Ibuprofen; Intestinal Mucosa; Lactulose; Male; Mannitol; Middle Aged; Occult Blood; Permeability; Sucrose | 2000 |
29 other study(ies) available for ibuprofen and mannitol
| Article | Year |
|---|---|
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caco-2 Cells; Cell Membrane Permeability; Heterocyclic Compounds; Humans; Protein Transport | 2003 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Synthesis and anti-inflammatory activity of novel biscoumarin-chalcone hybrids.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chalcone; Coumarins; Edema; Microsomes; Rats | 2011 |
Identification of hydrogen peroxide and hydroxyl radicals as mediators of leukocyte-induced myocardial dysfunction. Limitation of infarct size with neutrophil inhibition and depletion.
Topics: Adenosine Triphosphatases; Animals; Butylated Hydroxytoluene; Calcium; Catalase; Dogs; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Ibuprofen; Indomethacin; Leukocytes; Male; Mannitol; Myocardial Infarction; Myocardium; Neutrophils; Sarcoplasmic Reticulum; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1985 |
Assessment of intestinal permeability changes induced by nonsteroidal anti-inflammatory drugs in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Carbon Radioisotopes; Cell Membrane Permeability; Chromium Radioisotopes; Dose-Response Relationship, Drug; Edetic Acid; Ibuprofen; Intestines; Inulin; Lactulose; Male; Mannitol; Methods; Peptic Ulcer; Piroxicam; Rats; Rats, Sprague-Dawley; Tritium | 1995 |
Cohesive, multicomponent, dense powder flow characterization by NIR.
Topics: Calibration; Chemistry, Pharmaceutical; Excipients; Ibuprofen; Least-Squares Analysis; Mannitol; Models, Statistical; Multivariate Analysis; Powders; Reproducibility of Results; Rheology; Spectroscopy, Near-Infrared; Technology, Pharmaceutical | 2007 |
Application of face centred central composite design to optimise compression force and tablet diameter for the formulation of mechanically strong and fast disintegrating orodispersible tablets.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Calcium Compounds; Chemistry, Pharmaceutical; Compressive Strength; Excipients; Factor Analysis, Statistical; Hardness; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Kinetics; Linear Models; Mannitol; Models, Chemical; Particle Size; Porosity; Reproducibility of Results; Silicates; Solubility; Starch; Tablets; Technology, Pharmaceutical | 2012 |
On the links between elastic constants and effective elastic behavior of pharmaceutical compacts: importance of poisson's ratio and use of bulk modulus.
Topics: Analgesics, Non-Narcotic; Calcium Phosphates; Cellulose; Drug Compounding; Elastic Modulus; Ibuprofen; Mannitol; Powders; Stress, Mechanical; Tablets | 2013 |
Evidence-based nanoscopic and molecular framework for excipient functionality in compressed orally disintegrating tablets.
Topics: Cellulose; Chemistry, Pharmaceutical; Drug Compounding; Excipients; Ibuprofen; Mannitol; Tablets; Theophylline | 2014 |
Linear, Mannitol-Based Poly(anhydride-esters) with High Ibuprofen Loading and Anti-Inflammatory Activity.
Topics: 3T3 Cells; Animals; Anti-Inflammatory Agents; Biocompatible Materials; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Delivery Systems; Elastomers; Fibroblasts; Ibuprofen; Mannitol; Mice; Polyesters; Polymers; Spectroscopy, Fourier Transform Infrared | 2015 |
A Transporter of Ibuprofen is Upregulated in MDCK I Cells under Hyperosmotic Culture Conditions.
Topics: Animals; Cell Line; Dogs; Ibuprofen; Madin Darby Canine Kidney Cells; Mannitol; Membrane Transport Proteins; Osmolar Concentration; Raffinose; Sodium Chloride; Urea | 2016 |
The suitability of common compressibility equations for characterizing plasticity of diverse powders.
Topics: Algorithms; Calcium Phosphates; Celecoxib; Cellulose; Compressive Strength; Excipients; Hardness; Ibuprofen; Lactose; Mannitol; Powders; Stearic Acids | 2017 |
Preparation of Ibuprofen Microparticles by Antisolvent Precipitation Crystallization Technique: Characterization, Formulation, and In Vitro Performance.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Precipitation; Crystallization; Drug Compounding; Excipients; Freeze Drying; Hypromellose Derivatives; Ibuprofen; Leucine; Mannitol; Particle Size; Poloxamer; Solubility; Solvents; Spectrum Analysis, Raman | 2018 |
Engineering of pharmaceutical cocrystals in an excipient matrix: Spray drying versus hot melt extrusion.
Topics: Crystallization; Desiccation; Drug Compounding; Excipients; Hot Temperature; Ibuprofen; Mannitol; Niacinamide; Polyethylene Glycols; Polyvinyls; Pyrrolidines; Xylitol | 2018 |
Preparation and characterization of multi-component tablets containing co-amorphous salts: Combining multimodal non-linear optical imaging with established analytical methods.
Topics: Administration, Oral; Arginine; Chemistry, Pharmaceutical; Drug Combinations; Drug Stability; Excipients; Ibuprofen; Indomethacin; Mannitol; Optical Imaging; Povidone; Salts; Solubility; Spectroscopy, Fourier Transform Infrared; Tablets; Technology, Pharmaceutical; X-Ray Diffraction; Xylitol | 2018 |
Small-Scale Spherical Granulation Using a Planetary Centrifugal Mixer.
Topics: Calorimetry, Differential Scanning; Centrifugation; Ibuprofen; Lactose; Mannitol; Particle Size; Powder Diffraction; Starch; Surface Properties | 2020 |
A tunable extruded 3D printing platform using thermo-sensitive pastes.
Topics: Cellulose; Delayed-Action Preparations; Diclofenac; Excipients; Gelatin; Glycerol; Hydrodynamics; Hypromellose Derivatives; Ibuprofen; Lactose; Mannitol; Printing, Three-Dimensional; Rheology; Technology, Pharmaceutical; Viscosity; Water | 2020 |
Functionality of disintegrants with different mechanisms after roll compaction.
Topics: Carboxymethylcellulose Sodium; Cellulose; Drug Compounding; Excipients; Ibuprofen; Mannitol; Povidone; Sodium Dodecyl Sulfate; Solubility; Tablets; Tensile Strength | 2020 |
Evaluation of two novel co-processed excipients for direct compression of orodispersible tablets and mini-tablets.
Topics: Acetaminophen; Chemistry, Pharmaceutical; Drug Compounding; Enalapril; Excipients; Ibuprofen; Mannitol; Tablets; Tensile Strength | 2021 |