ibuprofen and lysine

ibuprofen has been researched along with lysine in 62 studies

Research

Studies (62)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (14.52)	18.7374
1990's	11 (17.74)	18.2507
2000's	22 (35.48)	29.6817
2010's	17 (27.42)	24.3611
2020's	3 (4.84)	2.80

Authors

Authors	Studies
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Motta, C	1
Caporalini, S; Pierboni, M; Spadoni, R	1
Marchese, C; Soldati, R; Tassini, T; Zucchi, A	1
Anselmi, F; Fattorini, L; Fioravanti, A; Franci, A; Marcolongo, R	1
Augustin, J; Kerkmann, T; Koselowske, G; Mangold, B; Martin, W; Töberich, H	1
Bird, HA; Fenn, GC; Hill, J; Lee, CE; Woodward, M; Wright, V	1
Voigt, W	1
Pavelka, K; Trnavsky, K	1
Ghezzi, P; White, CW	1
Cecchi, A; Marini, U; Venturino, M	1
Malecek, J; Pavelka, K; Susta, A; Vojtísek, O	1
Alessandrini, A; Gemini, R	1
Barabino, A; Corsini, G; Puppo, F; Zavarise, GM	1
Bidlingmaier, A; Hammermaier, A; Nagyiványi, P; Pabst, G; Waitzinger, J	1
Müller, P; Simon, B	1
Garrett, ER; Gtówka, FK; Hermann, TW	1
Haruta, A; Kodama, H; Otagiri, M; Suenaga, A; Takamura, N; Tsuruoka, M; Yamasaki, K	1
Nerli, B; Picó, G; Romanini, D	1
Müller-Goymann, CC; Schröder, K; Stoye, I	1
de los Santos, AR; Di Girolamo, G; Faletti, A; Gimeno, MA; Martí, ML; Zmijanovich, R	1
Główka, FK	1
Candiani, M; Covini, D; Elli, M; Frigerio, A; Gaffuri, B; Vignali, M; Zanardelli, M	1
Drukker, A; Guignard, JP	1
De Los Santos, AR; Di Girolamo, G; Kaminker, AJ; Kramer, EH; Martí, ML; Sassetti, B	1
Bazzi, MD; Duhaiman, AS; Rabbani, N	1
Artusi, M; Bettini, R; Colombo, G; Colombo, P; Nicoli, S; Padula, C; Rimondi, S; Rizzo, P; Santi, P	1
Davies, C; DeVoss, JJ; Gillam, EM; Graham, SE; Pearson, A; Scott, JR; Witham, K	1
Baydoun, L; Daniels, R; Drust, A; Düvel, A; Goldhagen, T; Müller-Goymann, CC; Schwan, I; Zeidler, C	1
Allegaert, K; Cossey, V; Devlieger, H; Langhendries, JP; Naulaers, G; Van Overmeire, B; Vanhole, C	1
Nicoli, S; Santi, P; Sebastiani, P	1
Cingolani, A; Ferrara, M; Valora, PD; Volonté, MG	1
Barbucci, R; Fini, M; Giardino, R; Giavaresi, G; Lamponi, S; Leone, G; Torricelli, P	1
Berndl, G; Klueglich, M; Liepold, B; Ring, A; Scheuerer, S; Schuijt, C; Trommeshauser, D	1
Allegaert, K; de Hoon, J; Devlieger, H; Guignard, JP; Tibboel, D; Van Overmeire, B; Vanhole, C	1
Bellini, C; Campone, F; Serra, G	1
Coombes, AG; Mohammed, AR; Perrie, Y	1
Chatterjee, N; Daugherty, SE; Fallin, MD; Hayes, RB; Huang, WY; Isaacs, WB; Platz, EA; Shugart, YY; Welch, R	1
Ambat, MT; Aranda, JV; Ostrea, EM	1
Eisinger, MJ; Hirt, D; Langhendries, JP; Marguglio, A; Schepens, P; Treluyer, JM; Urien, S; Van Overmeire, B	1
Corff, KE; Sekar, KC	1
Aranda, JV; Baggs, G; Carlo, WA; Clyman, R; Cox, B; Darko, L; Seth, A; Shalwitz, R; Sosenko, I; Van Overmeire, B; Ward, RM; Wozniak, P	1
Amin, SB; Miravalle, N	1
Bersani, I; Cota, F; De Carolis, MP; De Rosa, G; Romagnoli, C	1
Aghai, ZH; Amendolia, B; Bhat, V; Lynn, M; Ritz, SB	1
Kumarshingri, PS; Sehgal, A	1
Caballero, F; Foradada, M; García-Montoya, E; Miñarro, M; Pérez-Lozano, P; Suñé-Negre, JM; Ticó, JR	1
Al-Remawi, M; Hamaidi, M; Hamam, F	1
Bueno-Perez, R; Calero, S; Dubbeldam, D; Gómez-Álvarez, P; Gutiérrez-Sevillano, JJ; Martin-Calvo, A; Merkling, PJ; van Erp, TS; Vlugt, TJ	1
Kellstein, D; Laurent, AL; Legg, TJ; Leyva, R	1
Masciocchi, N; Vladiskovic, C	1
Kos, B; Obad, J; Šušković, J	1
Antonijoan, RM; Ballester, MR; Coimbra, J; Ferrero-Cafiero, JM; Font, X; Gich, I; Martínez, J; Mathison, Y; Puntes, M; Tarré, M	1
Dumičić, A; Kitak, T; Planinšek, O; Šibanc, R; Srčič, S	1
Antonijoan, RM; Ferrero-Cafiero, JM; Font, X; García-Arieta, A; Gich, I; Morales-Alcelay, S; Puntes, M; Tarré, M	1
Botros, YY; Ferris, DP; Hartlieb, KJ; Holcroft, JM; Kandela, I; Nassar, MS; Stern, CL; Stoddart, JF	1
Allegretti, M; Antonosante, A; Aramini, A; Benedetti, E; Brandolini, L; Castelli, V; Catanesi, M; Cimini, A; Cristiano, L; d'Angelo, M; Giordano, A; Luini, A; Mayo, E; Parashuraman, S; Villa, S	1
Addis, R; Hall, J; Hutchings, S; Jenner, B; Miles, L	1
Lange, R; Mück, T; Schepers, C; Weiser, T	1
Abdullah, KM; Al Jaseem, MAJ; Naseem, I; Qais, FA; Shamsi, A	1
Douroumis, D; Mithu, MSH; Muoka, LC; Nandi, U; Ross, SA	1

Reviews

1 review(s) available for ibuprofen and lysine

Article	Year
Treatment of patent ductus arteriosus: indomethacin or ibuprofen? Journal of perinatology : official journal of the California Perinatal Association, 2008, Volume: 28 Suppl 1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Lysine	2008

Trials

17 trial(s) available for ibuprofen and lysine

Article	Year
Pharmacokinetics and absolute bioavailability of ibuprofen after oral administration of ibuprofen lysine in man. Biopharmaceutics & drug disposition, 1990, Volume: 11, Issue:3 Topics: Administration, Oral; Adult; Biological Availability; Chromatography, High Pressure Liquid; Half-Life; Humans; Ibuprofen; Injections, Intravenous; Lysine; Male	1990
A double-blind crossover study to compare lysine acetyl salicylate (Aspergesic) with ibuprofen in the treatment of rheumatoid arthritis. Journal of clinical pharmacy and therapeutics, 1990, Volume: 15, Issue:3 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Double-Blind Method; Female; Humans; Ibuprofen; Lysine; Male; Randomized Controlled Trials as Topic; Salicylates	1990
[The dynamics of the analgesic effect of non-steroidal antirheumatic drugs. Ibuprofenlysinate versus diclofenac]. Fortschritte der Medizin, 1989, Apr-20, Volume: 107, Issue:12 Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Humans; Ibuprofen; Lysine; Pain Measurement; Random Allocation	1989
[Comparative clinical study of the efficacy of and tolerance for lysine para-isobutylphenyl propionate in parallel with indomethacin and pyrasanone]. La Clinica terapeutica, 1980, Jul-31, Volume: 94, Issue:2 Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Drug Tolerance; Female; Humans; Ibuprofen; Indomethacin; Lysine; Male; Middle Aged; Phenylbutazone; Rheumatic Diseases; Time Factors	1980
Gastrointestinal blood loss induced by three different non-steroidal anti-inflammatory drugs. Arzneimittel-Forschung, 1995, Volume: 45, Issue:4 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chromium Radioisotopes; Clonixin; Cyclooxygenase Inhibitors; Erythrocytes; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Lysine; Male; Middle Aged; Occult Blood	1995
Effects of ibuprofen lysinate and acetylsalicylic acid on gastric and duodenal mucosa. Randomized single-blind placebo-controlled endoscopic study in healthy volunteers. Arzneimittel-Forschung, 1994, Volume: 44, Issue:7 Topics: Adult; Aspirin; Duodenum; Endoscopy; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Intestinal Mucosa; Irritants; Lysine; Male; Single-Blind Method	1994
[Menstrual prostaglandin and dysmenorrhea: modulation by non-steroidal antiinflammatory drugs]. Medicina, 1999, Volume: 59, Issue:3 Topics: Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Double-Blind Method; Dysmenorrhea; Female; Humans; Ibuprofen; Lysine; Menstrual Cycle; Prospective Studies; Prostaglandins; Statistics, Nonparametric	1999
Effect of a single dose of ibuprofen lysinate before embryo transfer on pregnancy rates in cows. Reproduction (Cambridge, England), 2001, Volume: 121, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Embryo Implantation; Embryo Transfer; Female; Ibuprofen; Lysine; Pregnancy; Prospective Studies	2001
Effects of co-administration of ibuprofen-lysine on the pharmacokinetics of amikacin in preterm infants during the first days of life. Biology of the neonate, 2004, Volume: 86, Issue:3 Topics: Amikacin; Bacterial Infections; Double-Blind Method; Gestational Age; Half-Life; Humans; Ibuprofen; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infusions, Intravenous; Lysine; Metabolic Clearance Rate; Placebos; Retrospective Studies	2004
Ibuprofen extrudate, a novel, rapidly dissolving ibuprofen formulation: relative bioavailability compared to ibuprofen lysinate and regular ibuprofen, and food effect on all formulations. Journal of clinical pharmacology, 2005, Volume: 45, Issue:9 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Chemistry, Pharmaceutical; Female; Food-Drug Interactions; Humans; Ibuprofen; Intestinal Absorption; Lysine; Male; Middle Aged; Pharmaceutic Aids; Povidone; Solubility; Tablets; Therapeutic Equivalency	2005
Variants in the alpha-Methylacyl-CoA racemase gene and the association with advanced distal colorectal adenoma. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2007, Volume: 16, Issue:8 Topics: Adenoma; Aged; Alleles; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; Case-Control Studies; Colonic Neoplasms; Female; Genetic Variation; Genotype; Glutamic Acid; Glycine; Haplotypes; Humans; Ibuprofen; Leucine; Lysine; Male; Methionine; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Racemases and Epimerases; Rectal Neoplasms; Serine; Valine	2007
A randomized, double-blind, placebo-controlled trial on intravenous ibuprofen L-lysine for the early closure of nonsymptomatic patent ductus arteriosus within 72 hours of birth in extremely low-birth-weight infants. American journal of perinatology, 2009, Volume: 26, Issue:3 Topics: Double-Blind Method; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Infant, Extremely Low Birth Weight; Infant, Newborn; Injections, Intravenous; Lysine; Male; Time Factors; Treatment Outcome; Ultrasonography	2009
Ibuprofen sodium is absorbed faster than standard Ibuprofen tablets: results of two open-label, randomized, crossover pharmacokinetic studies. Drugs in R&D, 2014, Volume: 14, Issue:4 Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Cross-Over Studies; Female; Gels; Humans; Ibuprofen; Lysine; Male; Middle Aged; Tablets; Therapeutic Equivalency; Time Factors; Young Adult	2014
Ibuprofen lysinate, quicker and less variable: relative bioavailability compared to ibuprofen base in a pediatric suspension dosage form. International journal of clinical pharmacology and therapeutics, 2015, Volume: 53, Issue:11 Topics: Administration, Oral; Adolescent; Adult; Age Factors; Analgesics, Non-Narcotic; Area Under Curve; Biological Availability; Chemistry, Pharmaceutical; Cross-Over Studies; Fasting; Female; Healthy Volunteers; Humans; Ibuprofen; Intestinal Absorption; Isomerism; Lysine; Male; Middle Aged; Pharmaceutical Solutions; Postprandial Period; Therapeutic Equivalency; Young Adult	2015
Impact of Chiral Bioanalytical Methods on the Bioequivalence of Ibuprofen Products Containing Ibuprofen Lysinate and Ibuprofen Base. Chirality, 2016, Volume: 28, Issue:5 Topics: Area Under Curve; Chemistry Techniques, Analytical; Female; Humans; Ibuprofen; Lysine; Male; Stereoisomerism; Therapeutic Equivalency	2016
Predicting rapid analgesic onset of ibuprofen salts compared with ibuprofen acid: T Current medical research and opinion, 2018, Volume: 34, Issue:8 Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Drug Compounding; Female; Humans; Ibuprofen; Lysine; Male	2018
Pharmacokinetic Properties of Ibuprofen (IBU) From the Fixed-Dose Combination IBU/Caffeine (400/100 mg; FDC) in Comparison With 400 mg IBU as Acid or Lysinate Under Fasted and Fed Conditions-Data From 2 Single-Center, Single-Dose, Randomized Crossover Stu Clinical pharmacology in drug development, 2019, Volume: 8, Issue:6 Topics: Adult; Area Under Curve; Caffeine; Cross-Over Studies; Fasting; Female; Food; Food-Drug Interactions; Healthy Volunteers; Humans; Ibuprofen; Lysine; Male; Middle Aged; Postprandial Period; Young Adult	2019

Other Studies

44 other study(ies) available for ibuprofen and lysine

Article	Year
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22 Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption	2007
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
[Therapeutic effectiveness and tolerability of p-isobutylphenylpropionate of lysine, in parenteral administration, in subjects with hyperalgic forms of rheumatic arthropathy]. La Clinica terapeutica, 1979, Nov-15, Volume: 91, Issue:3 Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Back Pain; Brachial Plexus Neuritis; Female; Humans; Ibuprofen; Joint Diseases; Lysine; Male; Middle Aged; Osteoarthritis; Palliative Care; Sciatica; Spinal Diseases	1979
[Lysine p-isobutyl-phenylpropionate in articular and extra-articular osteoarthritis]. La Clinica terapeutica, 1979, Apr-15, Volume: 89, Issue:1 Topics: Adult; Aged; Anti-Inflammatory Agents; Drug Evaluation; Drug Tolerance; Female; Hip Joint; Humans; Ibuprofen; Knee Joint; Lysine; Male; Middle Aged; Osteoarthritis; Spondylitis	1979
[Clinical observations with a preparation with a base of 4-isobutylphenyl-2-propionate of lysine in degenerative rheumatic diseases]. La Clinica terapeutica, 1979, Dec-15, Volume: 91, Issue:5 Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Drug Evaluation; Female; Humans; Ibuprofen; Lysine; Male; Middle Aged	1979
Clinical efficacy and tolerance of galactosoaminoglucuronoglycan sulfate in the treatment of osteoarthritis. Drugs under experimental and clinical research, 1991, Volume: 17, Issue:1 Topics: Adult; Aged; Female; Glycosaminoglycans; Humans; Ibuprofen; Lysine; Male; Middle Aged; Osteoarthritis	1991
[Postoperative monitoring of pain under ibuprofen lysinate]. Deutsche zahnarztliche Zeitschrift, 1990, Volume: 45, Issue:1 Topics: Adult; Female; Humans; Ibuprofen; Lysine; Male; Molar, Third; Pain, Postoperative; Tooth Extraction	1990
Protection against pulmonary oxygen toxicity by interleukin-1 and tumor necrosis factor: role of antioxidant enzymes and effect of cyclooxygenase inhibitors. Biotherapy (Dordrecht, Netherlands), 1989, Volume: 1, Issue:4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Enzymes; Ibuprofen; Interleukin-1; Lung Diseases; Lysine; Male; Oxygen; Rats; Rats, Inbred Strains; Tumor Necrosis Factor-alpha	1989
[Lack of interaction between ibuprofen lysinate and oral anticoagulants]. La Clinica terapeutica, 1985, Jan-15, Volume: 112, Issue:1 Topics: Aged; Anticoagulants; Drug Interactions; Female; Humans; Ibuprofen; Lysine; Male; Middle Aged	1985
[Ibuprofenlysinate in the treatment of osteoarthrosis]. Fysiatricky a reumatologicky vestnik, 1983, Volume: 61, Issue:1 Topics: Adult; Aged; Female; Humans; Ibuprofen; Lysine; Male; Middle Aged; Osteoarthritis	1983
[Evaluation of the effect of ibuprofen lysinate on lymphocytic transformation in vitro. Comparison with meglumine indomethacinate, phenylbutazone, and lysine acetylsalicylate]. Il Farmaco; edizione pratica, 1980, Volume: 35, Issue:4 Topics: Anti-Inflammatory Agents; Aspirin; Humans; Ibuprofen; Indomethacin; Lymphocyte Activation; Lysine; Meglumine; Phenylbutazone	1980
Bioavailability of racemic ibuprofen and its lysinate from suppositories in rabbits. Journal of pharmaceutical sciences, 1993, Volume: 82, Issue:11 Topics: Animals; Biological Availability; Dose-Response Relationship, Drug; Female; Ibuprofen; Lysine; Male; Rabbits; Stereoisomerism; Suppositories; Surface-Active Agents	1993
Mode of interaction of loop diuretics with human serum albumin and characterization of binding site. Pharmaceutical research, 1996, Volume: 13, Issue:7 Topics: Binding Sites; Diuretics; Fluorescent Dyes; Furosemide; Humans; Ibuprofen; Lysine; Protein Binding; Serum Albumin; Sulfonamides; Warfarin	1996
Structural specificity requirements in the binding of beta lactam antibiotics to human serum albumin. Chemico-biological interactions, 1997, May-02, Volume: 104, Issue:2-3 Topics: Acid-Base Equilibrium; Anti-Inflammatory Agents, Non-Steroidal; Bilirubin; Binding Sites; Binding, Competitive; Cephalosporins; Coumarins; Esterases; Fatty Acids; Glycosylation; Histidine; Humans; Hydrogen-Ion Concentration; Ibuprofen; Indicators and Reagents; Kinetics; Ligands; Lysine; Protein Binding; Serum Albumin; Spectrometry, Fluorescence; Structure-Activity Relationship; Temperature; Ultrafiltration	1997
Transformation of a liposomal dispersion containing ibuprofen lysinate and phospholipids into mixed micelles - physico-chemical characterization and influence on drug permeation through excised human stratum corneum. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 1998, Volume: 46, Issue:2 Topics: Cell Membrane Permeability; Drug Carriers; Epidermis; Humans; Ibuprofen; In Vitro Techniques; Liposomes; Lysine; Micelles; Microscopy, Electron; Phosphatidylcholines; Phospholipids	1998
Stereoselective pharmacokinetics of ibuprofen and its lysinate from suppositories in rabbits. International journal of pharmaceutics, 2000, Apr-20, Volume: 199, Issue:2 Topics: Animals; Chromatography, High Pressure Liquid; Ibuprofen; Lysine; Rabbits; Rectum; Stereoisomerism; Suppositories	2000
Ibuprofen-lysine for closure of patent ductus arteriosus. Acta paediatrica (Oslo, Norway : 1992), 2001, Volume: 90, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Ductus Arteriosus, Patent; Humans; Ibuprofen; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Kidney; Lysine	2001
[Effects of lysine clonixinate on platelet function. Comparison with other non-steroidal anti-inflammatory agents]. Medicina, 2001, Volume: 61, Issue:3 Topics: Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Platelets; Clonixin; Diclofenac; Flow Cytometry; Humans; Ibuprofen; Lysine; Male; P-Selectin; Platelet Aggregation; Platelet Count; Platelet Function Tests	2001
Inhibition of camel lens zeta-crystallin by aspirin and aspirin-like analgesics. The international journal of biochemistry & cell biology, 2002, Volume: 34, Issue:1 Topics: Acetaminophen; Analgesics; Animals; Aspirin; Binding Sites; Binding, Competitive; Camelus; Crystallins; Ibuprofen; In Vitro Techniques; Kinetics; Lysine; NADP; Phenanthrenes; Pyridoxal Phosphate	2002
Post-iontophoresis transport of ibuprofen lysine across rabbit ear skin. International journal of pharmaceutics, 2003, Nov-06, Volume: 266, Issue:1-2 Topics: Animals; Biological Transport; Ear; Ibuprofen; In Vitro Techniques; Iontophoresis; Lysine; Permeability; Rabbits; Skin	2003
Assessment of arginine 97 and lysine 72 as determinants of substrate specificity in cytochrome P450 2C9 (CYP2C9). Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:4 Topics: Animals; Arginine; Aryl Hydrocarbon Hydroxylases; Base Sequence; Binding Sites; Cytochrome P-450 CYP2C9; Diclofenac; Escherichia coli; Gene Expression; Hemeproteins; Holoenzymes; Humans; Ibuprofen; Lysine; Models, Molecular; Mutagenesis, Site-Directed; NADPH-Ferrihemoprotein Reductase; Naproxen; Peptide Fragments; Recombinant Proteins; Sequence Homology, Nucleic Acid; Substrate Specificity	2004
Comparison of different ibuprofen-amino acid compounds with respect to emulsifying and cytotoxic properties. International journal of pharmaceutics, 2004, Apr-15, Volume: 274, Issue:1-2 Topics: Adult; Animals; Arginine; Cornea; Drug Combinations; Drug Stability; Emulsifying Agents; Emulsions; Erythrocytes; Hemolysis; Humans; Ibuprofen; Lysine; Male; Surface Tension; Swine	2004
Effect of lactic acid and iontophoresis on drug permeation across rabbit ear skin. International journal of pharmaceutics, 2005, Mar-23, Volume: 292, Issue:1-2 Topics: Acetaminophen; Administration, Topical; Animals; Biological Availability; Buspirone; Cell Membrane Permeability; Drug Evaluation, Preclinical; Ear; Excipients; Ibuprofen; Iontophoresis; Lactic Acid; Lysine; Rabbits; Skin Absorption	2005
Stability of ibuprofen in injection solutions. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2005, Mar-15, Volume: 62, Issue:6 Topics: Anti-Inflammatory Agents, Non-Steroidal; Child, Preschool; Chromatography, High Pressure Liquid; Drug Stability; Drug Storage; Humans; Ibuprofen; Injections, Intravenous; Lysine; Pediatrics; Phlebitis; Solutions	2005
Hyaluronic acid hydrogel added with ibuprofen-lysine for the local treatment of chondral lesions in the knee: in vitro and in vivo investigations. Journal of biomedical materials research. Part B, Applied biomaterials, 2005, Volume: 75, Issue:1 Topics: Animals; Cell Line; Chondrocytes; Hyaluronic Acid; Hydrogel, Polyethylene Glycol Dimethacrylate; Ibuprofen; Knee Joint; Lysine; Male; Rabbits	2005
Nonselective cyclo-oxygenase inhibitors and glomerular filtration rate in preterm neonates. Pediatric nephrology (Berlin, Germany), 2005, Volume: 20, Issue:11 Topics: Amikacin; Aspirin; Cyclooxygenase Inhibitors; Glomerular Filtration Rate; Humans; Ibuprofen; Infant, Newborn; Lysine	2005
Pulmonary hypertension following L-lysine ibuprofen therapy in a preterm infant with patent ductus arteriosus. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2006, Jun-20, Volume: 174, Issue:13 Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Fatal Outcome; Humans; Hypertension, Pulmonary; Hypoxia; Ibuprofen; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Lysine	2006
Amino acids as cryoprotectants for liposomal delivery systems. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2007, Volume: 30, Issue:5 Topics: Amino Acids; Arginine; Chemistry, Pharmaceutical; Cholesterol; Cryoprotective Agents; Drug Carriers; Drug Compounding; Freeze Drying; Histidine; Ibuprofen; Lipids; Liposomes; Lysine; Particle Size; Phosphatidylcholines; Solubility; Technology, Pharmaceutical; Temperature; Time Factors; Trehalose; Viscosity; Water	2007
Effect of ibuprofen L-lysinate on bilirubin binding to albumin as measured by saturation index and horseradish peroxidase assays. Journal of perinatology : official journal of the California Perinatal Association, 2008, Volume: 28, Issue:4 Topics: Anti-Inflammatory Agents, Non-Steroidal; Bilirubin; Dose-Response Relationship, Drug; Horseradish Peroxidase; Humans; Ibuprofen; In Vitro Techniques; Infant, Newborn; Infant, Premature; Lysine; Protein Binding; Serum Albumin	2008
An optimized ibuprofen dosing scheme for preterm neonates with patent ductus arteriosus, based on a population pharmacokinetic and pharmacodynamic study. British journal of clinical pharmacology, 2008, Volume: 65, Issue:5 Topics: Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Ductus Arteriosus, Patent; Humans; Ibuprofen; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Infusions, Intravenous; Logistic Models; Lysine; Respiratory Distress Syndrome, Newborn	2008
Effect of ibuprofen on bilirubin-albumin binding affinity in premature infants. Journal of perinatal medicine, 2011, Volume: 39, Issue:1 Topics: Albumins; Bilirubin; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Hyperbilirubinemia; Ibuprofen; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Lysine; Male; Prospective Studies	2011
Ibuprofen lysinate and sodium ibuprofen for prophylaxis of patent ductus arteriosus in preterm neonates. Indian pediatrics, 2012, Volume: 49, Issue:1 Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Infant, Newborn; Infant, Premature, Diseases; Lysine; Retrospective Studies; Treatment Outcome	2012
Severe pulmonary hypertension with therapeutic L-lysine ibuprofen in 2 preterm neonates. Pediatrics, 2012, Volume: 129, Issue:5 Topics: Anti-Inflammatory Agents, Non-Steroidal; Diseases in Twins; Ductus Arteriosus, Patent; Echocardiography; Fatal Outcome; Humans; Hypertension, Pulmonary; Ibuprofen; Infant, Newborn; Infant, Premature, Diseases; Infant, Small for Gestational Age; Lysine; Male	2012
Pulmonary hypertension in an infant treated with ibuprofen. Indian journal of pediatrics, 2013, Volume: 80, Issue:8 Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Hypertension, Pulmonary; Ibuprofen; Infant, Premature; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Lysine	2013
Characterization of alginate beads loaded with ibuprofen lysine salt and optimization of the preparation method. International journal of pharmaceutics, 2014, Jan-02, Volume: 460, Issue:1-2 Topics: Alginates; Anti-Inflammatory Agents, Non-Steroidal; Calcium Chloride; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Glucuronic Acid; Hexuronic Acids; Hydrogen-Ion Concentration; Ibuprofen; Lysine; Microscopy, Electron, Scanning	2014
Quality by design approach to prepare oleoyl alginate derivative and its use in transdermal delivery. Pharmaceutical development and technology, 2015, Volume: 20, Issue:2 Topics: Administration, Cutaneous; Alginates; Animals; Drug Carriers; Drug Design; Gels; Ibuprofen; In Vitro Techniques; Lysine; Oleic Acids; Particle Size; Polysaccharides; Rabbits; Skin; Skin Absorption; Solubility; Spectroscopy, Fourier Transform Infrared; Surface Properties; Surface Tension; Viscosity	2015
Enantioselective adsorption of ibuprofen and lysine in metal-organic frameworks. Chemical communications (Cambridge, England), 2014, Sep-25, Volume: 50, Issue:74 Topics: Adsorption; Ibuprofen; Lysine; Metals; Porosity; Pyridines; Stereoisomerism	2014
Reversibly changing a painkiller structure: a hot topic for a cold case--ibuprofen lysine salt. Journal of pharmaceutical and biomedical analysis, 2015, Mar-25, Volume: 107 Topics: Calorimetry, Differential Scanning; Crystallization; Crystallography, X-Ray; Ibuprofen; Lysine; Molecular Conformation; Phase Transition; Temperature; X-Ray Diffraction	2015
Antimicrobial activity of ibuprofen: new perspectives on an "Old" non-antibiotic drug. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2015, Apr-25, Volume: 71 Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspergillus; Bacteria; Candida albicans; Ibuprofen; Lysine	2015
Determination of Solubility Parameters of Ibuprofen and Ibuprofen Lysinate. Molecules (Basel, Switzerland), 2015, Dec-03, Volume: 20, Issue:12 Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Gas; Drug Carriers; Excipients; Ibuprofen; Lysine; Solvents; Technology, Pharmaceutical	2015
Encapsulation of Ibuprofen in CD-MOF and Related Bioavailability Studies. Molecular pharmaceutics, 2017, 05-01, Volume: 14, Issue:5 Topics: Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Cyclodextrins; gamma-Cyclodextrins; Ibuprofen; Lysine; Solubility	2017
Differential protein modulation by ketoprofen and ibuprofen underlines different cellular response by gastric epithelium. Journal of cellular physiology, 2018, Volume: 233, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arginine; Cell Survival; Cytoprotection; Drug Combinations; Epithelial Cells; Ethanol; Gastric Mucosa; Gene Expression Profiling; Gene Regulatory Networks; Humans; Ibuprofen; Ketoprofen; Lysine; MCF-7 Cells; Oligonucleotide Array Sequence Analysis; Real-Time Polymerase Chain Reaction; Time Factors; Transcriptome	2018
Mechanistic insight into glycation inhibition of human serum albumin by vitamin B9: Multispectroscopic and molecular docking approach. International journal of biological macromolecules, 2021, Jun-30, Volume: 181 Topics: Binding Sites; Circular Dichroism; Folic Acid; Glycation End Products, Advanced; Glycosylation; Humans; Ibuprofen; Lysine; Molecular Docking Simulation; Osmolar Concentration; Protein Carbonylation; Protein Structure, Secondary; Serum Albumin, Human; Spectrometry, Fluorescence; Spectrum Analysis; Sulfhydryl Compounds; Thermodynamics; Warfarin	2021
Comparative taste-masking evaluation of microencapsulated bitter drugs using Smartseal 30D and ReadyMix for paediatric dosage forms. AAPS PharmSciTech, 2021, Apr-21, Volume: 22, Issue:4 Topics: Administration, Oral; Child; Dosage Forms; Drug Compounding; Humans; Ibuprofen; Lysine; Pharmaceutical Preparations; Polymers; Solubility; Taste	2021