ibuprofen has been researched along with lidocaine in 83 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.20) | 18.7374 |
| 1990's | 5 (6.02) | 18.2507 |
| 2000's | 25 (30.12) | 29.6817 |
| 2010's | 40 (48.19) | 24.3611 |
| 2020's | 12 (14.46) | 2.80 |
| Authors | Studies |
|---|---|
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Caron, G; Ermondi, G | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Bennis, K; Ducki, S; Lesage, F; Vivier, D | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Bianchine, JR; Gerber, MC; Gerber, N; Tejwani, GA | 1 |
| Rawling, M; Wiebe, ER | 1 |
| Hamilton, J | 1 |
| Eggers, KA; Smith, AJ; Stacey, MR | 1 |
| Paavola, A; Rosenberg, P; Tarkkila, P; Wahlström, T; Xu, M; Yliruusi, J | 1 |
| Paavola, A; Rosenberg, P; Yliruusi, J | 1 |
| Hadgraft, J; Valenta, C | 1 |
| Beck, M; Gallatin, E; Nist, R; Reader, A | 1 |
| Erickson, TE; Gebhart, GF; Johnson, WT; Law, AS; Locher-Claus, MT | 1 |
| Bramer, T; Dew, N; Edsman, K | 1 |
| Ipp, M; Manley, J; Potash, L; Sgro, M; Shah, V; Taddio, A | 1 |
| Elkharraz, K; Klose, D; Siepmann, F; Siepmann, J | 1 |
| Alencar, FG; Venâncio, Rde A; Zamperini, C | 1 |
| Johnson, CJ; Lambertz, CK; Maxwell, JR; Montgomery, PG | 1 |
| Fry, R; Ring, P | 1 |
| Lundberg, GD | 1 |
| Chhabra, A; Jyoti, B; Nandi, B; Pandey, R; Sinha, R; Subramaniam, R | 1 |
| Kressel, HY | 1 |
| Descamps, M; Klose, D; Siepmann, F; Siepmann, J; Willart, JF | 1 |
| Burke, A; Cansino, C; Edelman, A; Jamshidi, R | 1 |
| Aggarwal, V; Kabi, D; Singla, M | 1 |
| Beck, M; Drum, M; Nusstein, J; Oleson, M; Reader, A | 1 |
| Briggs, M; Nelson, EA | 1 |
| Abbott, PV; Ashouri, R; Askarifard, S; Nakhaee, N; Pardakhti, A; Parirokh, M; Rekabi, AR | 1 |
| Mata, JL; Restolho, J; Saramago, B | 1 |
| Hessler, I; Panfil, EM | 1 |
| Ebtehaj, I; Kaviani, N; Khademi, A; Mohammadi, Z | 1 |
| Almeida, IF; Costa, P; Freire, CS; Neto, CP; Pinto, PC; Rosado, C; Silvestre, AJ; Trovatti, E | 1 |
| Danède, F; Delplace, C; Descamps, M; Klose, D; Kreye, F; Siepmann, F; Siepmann, J | 1 |
| Abbott, PV; Manochehrifar, H; Nakhaee, N; Parirokh, M; Reza Forghani, F; Yosefi, MH | 1 |
| Briggs, M; Martyn-St James, M; Nelson, EA | 1 |
| Abdolrahimi, M; Mokhtari, H; Narimani, S; Nezafati, S; Rahimi, S; Shahi, S; Yavari, HR | 1 |
| Galluzzi, KE; Stanos, SP | 1 |
| Allen, RH; Bartz, D; Bernholc, A; Hubacher, D; Lopez, LM; O'Brien, PA; Zeng, Y | 1 |
| Bhuiyan, AKMMH; Waters, LJ | 1 |
| Abubakr, NH; Elzaki, WM; Ibrahim, YE; Ziada, HM | 1 |
| Byrne, A; Fleming, P; King, G | 1 |
| Chowdhury, SR; Gokara, M; Narayana, VV; Ramachary, DB; Sadarangani, V; Subramanyam, R; Varkala, S | 1 |
| Du, G; Kang, L; Kathuria, H; Li, H; Ruan, X; Sun, Y | 1 |
| Beck, M; Bultema, K; Drum, M; Fowler, S; Nusstein, J; Reader, A | 1 |
| Bogni, A; Carafa, M; Del Favero, E; Di Marzio, L; Marianecci, C; Paolino, D; Pieretti, S; Ponti, J; Rinaldi, F; Rondelli, V; Rossi, F | 1 |
| Goto, S; Kataoka, H; Komatsu, K; Sakaki, Y; Shimada, Y | 1 |
| Matute Crespo, M; Montero Matamala, A | 1 |
| Jiang, Q; Li, A; Li, X; Ma, C; Yu, S | 1 |
| Tamaki, A; Thuener, J; Weidenbecher, M | 1 |
| Brandenbusch, C; Sadowski, G; Wolbert, F | 1 |
| Brown, SP; Lewandowski, JR; Mann, SK; McQueen, LL; Pham, TN | 1 |
| Almeida, TS; Carvalho, JPF; Freire, CSR; Mota, JP; Rosado, C; Silva, NHCS; Silvestre, AJD; Vilela, C | 1 |
| Cao, Y; Li, C; Meng, X; Wang, H; Zhang, S; Zhang, Y | 1 |
| Bazybek, N; Ma, G; Wei, Y; Wen, K; Wu, Y | 1 |
| Glatz, Z; Michalcová, L; Nevídalová, H | 1 |
| Gill, GS; Jain, N; Kalra, T; Kumar, M; Singla, R | 1 |
| Mori, K; Oshizaka, T; Sugibayashi, K; Takei, C; Todo, H; Usuzaka, E | 1 |
| Kiaee, G; Rezaei Nejad, H; Sadeqi, A; Sonkusale, S; Zeng, W | 1 |
| Alabaz, D; Albayrak, E; Bedir, T; Bozdemir, ŞE; Büyükcam, A; Çelebi, S; Çiftçi, E; İlarslan, EÇ; Kara, A; Kara, M; Kara, SS; Kara, TT; Karakaşlılar, S; Karbuz, A; Kaya, C; Öz, FN; Özdemir, H; Sali, E; Somer, A; Sönmez, G; Sütçü, M; Tezer, H | 1 |
| Badr, AE; Elnaghy, AM; Elsaka, SE; Elshazli, AH | 1 |
| Elnaghy, AM; Elsaka, SE; Elshazli, AH | 1 |
| da Rosa, RA; Lenzi, TL; Silva, IA; Só, GB; Só, MVR; Weissheimer, T | 1 |
11 review(s) available for ibuprofen and lidocaine
| Article | Year |
|---|---|
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship | 2016 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Drug interactions with cimetidine: an update.
Topics: Absorption; Acetaminophen; Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Anti-Bacterial Agents; Anticoagulants; Anticonvulsants; Aspirin; Aziridines; Benzodiazepines; Benzoquinones; Cimetidine; Drug Interactions; Humans; Ibuprofen; Imipramine; Kinetics; Lidocaine; Liver Circulation; Pituitary Gland; Procaine; Xanthines | 1985 |
Topical agents or dressings for pain in venous leg ulcers.
Topics: Administration, Topical; Analgesics, Non-Narcotic; Anesthetics, Local; Bandages; Debridement; Humans; Ibuprofen; Leg Ulcer; Lidocaine; Ointments; Pain; Prilocaine; Randomized Controlled Trials as Topic | 2010 |
[Ulcus curis venosum: topical drugs and dressings in evaluation. How effective are the measures in terms of pain management?].
Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Bandages; Cross-Over Studies; Debridement; Humans; Ibuprofen; Lidocaine; Lidocaine, Prilocaine Drug Combination; Pain Management; Pain Measurement; Prilocaine; Quality of Life; Randomized Controlled Trials as Topic; Varicose Ulcer | 2011 |
Topical agents or dressings for pain in venous leg ulcers.
Topics: Administration, Topical; Analgesics; Anesthetics, Local; Bandages; Debridement; Humans; Ibuprofen; Leg Ulcer; Lidocaine; Lidocaine, Prilocaine Drug Combination; Ointments; Pain; Prilocaine; Randomized Controlled Trials as Topic; Varicose Ulcer | 2012 |
Topical therapies in the management of chronic pain.
Topics: Administration, Cutaneous; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Chronic Pain; Diclofenac; Humans; Ibuprofen; Irritants; Ketoprofen; Lidocaine; Musculoskeletal Pain; Neoplasms; Neuralgia; Neuralgia, Postherpetic; Osteoarthritis, Knee; Palliative Care | 2013 |
Interventions for pain with intrauterine device insertion.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Intrauterine Devices; Lidocaine; Misoprostol; Naproxen; Oxytocics; Pain; Prilocaine; Randomized Controlled Trials as Topic | 2015 |
Superior Laryngeal Nerve Neuralgia: Case Series and Review of Anterior Neck Pain Syndromes.
Topics: Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Female; Humans; Ibuprofen; Injections; Laryngeal Nerves; Lidocaine; Male; Middle Aged; Neck Pain; Neuralgia; Pain Measurement; Retreatment; Syndrome; Triamcinolone Acetonide; Young Adult | 2019 |
Recent research and development of local anesthetic-loaded microspheres.
Topics: Anesthetics, Local; Animals; Bupivacaine; Delayed-Action Preparations; Dexmedetomidine; Drug Carriers; Drug Compounding; Drug Liberation; Emulsions; Humans; Hydrogels; Ibuprofen; Lactates; Lidocaine; Microfluidics; Microspheres; Polyesters; Polyethylene Glycols; Polylactic Acid-Polyglycolic Acid Copolymer; Solvents; Temperature | 2020 |
Do NSAIDs used prior to standard inferior alveolar nerve blocks improve the analgesia of mandibular molars with irreversible pulpitis? An umbrella review.
Topics: Analgesia; Anesthesia, Dental; Anesthetics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Humans; Ibuprofen; Lidocaine; Mandibular Nerve; Molar; Nerve Block; Pulpitis | 2023 |
19 trial(s) available for ibuprofen and lidocaine
| Article | Year |
|---|---|
Pain control in abortion.
Topics: Abortion, Therapeutic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Female; Humans; Ibuprofen; Lidocaine; Pain; Pain Measurement; Pregnancy; Prospective Studies | 1995 |
Topical ibuprofen for skin analgesia prior to venepuncture.
Topics: Administration, Topical; Analgesia; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Catheterization, Peripheral; Double-Blind Method; Drug Combinations; Humans; Ibuprofen; Lidocaine; Lidocaine, Prilocaine Drug Combination; Pain; Phlebotomy; Prilocaine | 1996 |
Pain reduction in untreated irreversible pulpitis using an intraosseous injection of Depo-Medrol.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Ibuprofen; Injections; Jaw; Lidocaine; Male; Methylprednisolone; Methylprednisolone Acetate; Pain Measurement; Placebos; Prospective Studies; Pulpitis; Sodium Chloride; Statistics as Topic; Statistics, Nonparametric; Surveys and Questionnaires; Toothache | 2000 |
Different substances and dry-needling injections in patients with myofascial pain and headaches.
Topics: Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Drug Combinations; Female; Follow-Up Studies; Glucocorticoids; Headache; Humans; Ibuprofen; Injections, Intramuscular; Lidocaine; Male; Middle Aged; Needles; Pain Measurement; Temporomandibular Joint Dysfunction Syndrome; Time Factors | 2008 |
Premedication to reduce discomfort during screening mammography.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Lidocaine; Mammography; Mass Screening; Middle Aged; Pain; Placebo Effect; Premedication; Treatment Outcome | 2008 |
Comparison of topical lignocaine gel and fentanyl for perioperative analgesia in children undergoing cataract surgery.
Topics: Administration, Topical; Analgesics, Opioid; Anesthesia, Intravenous; Anesthesia, Local; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cataract Extraction; Child; Child, Preschool; Double-Blind Method; Female; Fentanyl; Heart Rate; Humans; Ibuprofen; Injections, Intravenous; Lidocaine; Male; Prospective Studies | 2009 |
Paracervical block with combined ketorolac and lidocaine in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Ketorolac; Lidocaine; Pain; Pregnancy; Young Adult | 2009 |
Comparative evaluation of effect of preoperative oral medication of ibuprofen and ketorolac on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical tri
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Ketorolac; Lidocaine; Male; Mandibular Nerve; Nerve Block; Preanesthetic Medication; Premedication; Prospective Studies; Pulpitis; Root Canal Therapy; Statistics, Nonparametric; Young Adult | 2010 |
Effect of preoperative ibuprofen on the success of the inferior alveolar nerve block in patients with irreversible pulpitis.
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Bicuspid; Chi-Square Distribution; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Lidocaine; Male; Mandible; Mandibular Nerve; Molar; Nerve Block; Preanesthetic Medication; Premedication; Prospective Studies; Pulpitis; Root Canal Therapy; Statistics, Nonparametric | 2010 |
The effect of premedication with ibuprofen and indomethacin on the success of inferior alveolar nerve block for teeth with irreversible pulpitis.
Topics: Adult; Analysis of Variance; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Indomethacin; Lidocaine; Male; Mandible; Mandibular Nerve; Molar; Nerve Block; Pain; Pain Measurement; Preanesthetic Medication; Premedication; Prospective Studies; Pulpitis; Root Canal Therapy; Treatment Outcome; Young Adult | 2010 |
The effect of orally administered ketamine on requirement for anesthetics and postoperative pain in mandibular molar teeth with irreversible pulpitis.
Topics: Adjuvants, Anesthesia; Administration, Oral; Adolescent; Adult; Analgesics; Anesthesia, Dental; Anesthetics, Dissociative; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Dental Pulp Test; Double-Blind Method; Humans; Ibuprofen; Ketamine; Lidocaine; Mandible; Mandibular Nerve; Middle Aged; Molar; Nerve Block; Pain, Postoperative; Pulpitis; Root Canal Therapy; Surveys and Questionnaires; Toothache; Young Adult | 2011 |
Effect of bupivacaine on postoperative pain for inferior alveolar nerve block anesthesia after single-visit root canal treatment in teeth with irreversible pulpitis.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Double-Blind Method; Epinephrine; Female; Follow-Up Studies; Humans; Ibuprofen; Lidocaine; Male; Mandibular Nerve; Middle Aged; Nerve Block; Pain Measurement; Pain, Postoperative; Pulpitis; Root Canal Therapy; Vasoconstrictor Agents; Young Adult | 2012 |
Effect of premedication with ibuprofen and dexamethasone on success rate of inferior alveolar nerve block for teeth with asymptomatic irreversible pulpitis: a randomized clinical trial.
Topics: Adult; Anesthetics, Local; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Asymptomatic Diseases; Dental Pulp Test; Dexamethasone; Double-Blind Method; Female; Follow-Up Studies; Humans; Ibuprofen; Lidocaine; Lip; Male; Mandibular Nerve; Molar; Nerve Block; Pain Measurement; Placebos; Premedication; Prospective Studies; Pulpitis; Root Canal Preparation | 2013 |
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Lidocaine; Male; Mefenamic Acid; Pain; Pain Measurement; Pain, Postoperative; Placebos; Pulpitis; Root Canal Preparation; Root Canal Therapy | 2016 |
Pain Reduction in Untreated Symptomatic Irreversible Pulpitis Using Liposomal Bupivacaine (Exparel): A Prospective, Randomized, Double-blind Trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Dental; Anesthesia, Local; Bupivacaine; Double-Blind Method; Emergency Medical Services; Epinephrine; Female; Humans; Ibuprofen; Lidocaine; Liposomes; Male; Mandibular Nerve; Narcotics; Nerve Block; Pain; Pain Measurement; Prospective Studies; Pulpitis; Root Canal Therapy; Vasoconstrictor Agents; Young Adult | 2016 |
Evaluating Combined Effect of Oral Premedication with Ibuprofen and Dexamethasone on Success of Inferior Alveolar Nerve Block in Mandibular Molars with Symptomatic Irreversible Pulpitis: A Prospective, Double-blind, Randomized Clinical Trial.
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Lidocaine; Mandibular Nerve; Molar; Nerve Block; Premedication; Prospective Studies; Pulpitis | 2021 |
The effectiveness of topical 1% lidocaine with systemic oral analgesics for ear pain with acute otitis media.
Topics: Acetaminophen; Acute Disease; Analgesics; Anti-Bacterial Agents; Child; Child, Preschool; Earache; Humans; Ibuprofen; Lidocaine; Otitis Media; Pain | 2022 |
Effect of preoperative tramadol, ibuprofen, ibuprofen/acetaminophen on the anaesthetic efficacy of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis.
Topics: Acetaminophen; Anesthesia, Dental; Anesthetics, Local; Double-Blind Method; Humans; Ibuprofen; Lidocaine; Mandibular Nerve; Nerve Block; Pulpitis; Tramadol | 2023 |
Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial.
Topics: Anesthesia, Dental; Anesthetics, Local; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Ketorolac; Lidocaine; Mandibular Nerve; Meloxicam; Nerve Block; Pain; Premedication; Prospective Studies; Pulpitis | 2023 |
53 other study(ies) available for ibuprofen and lidocaine
| Article | Year |
|---|---|
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Premature babies and pharmacology.
Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Central Nervous System Stimulants; Drug Combinations; Humans; Ibuprofen; Infant, Newborn; Infant, Premature; Lidocaine; Lidocaine, Prilocaine Drug Combination; Pharmacology; Prilocaine | 1995 |
Controlled release gel of ibuprofen and lidocaine in epidural use--analgesia and systemic absorption in pigs.
Topics: Absorption; Analgesia, Epidural; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Biological Availability; Delayed-Action Preparations; Drug Delivery Systems; Dura Mater; Female; Gels; Ibuprofen; Injections, Epidural; Lidocaine; Poloxalene; Surface-Active Agents; Swine | 1998 |
Controlled release and dura mater permeability of lidocaine and ibuprofen from injectable poloxamer-based gels.
Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Dura Mater; Gels; Hydrogen-Ion Concentration; Ibuprofen; Injections; Lidocaine; Permeability; Poloxalene; Viscosity | 1998 |
pH, pK(a) and dermal delivery.
Topics: Administration, Cutaneous; Humans; Hydrogen-Ion Concentration; Ibuprofen; Lidocaine; Permeability | 2000 |
Effects of pre-emptive morphine, ibuprofen or local anesthetic on fos expression in the spinal trigeminal nucleus following tooth pulp exposure in the rat.
Topics: Analgesics, Opioid; Analysis of Variance; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Dental Pulp Exposure; Ibuprofen; Lidocaine; Morphine; Pain, Postoperative; Preoperative Care; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Toothache; Trigeminal Caudal Nucleus | 2005 |
Catanionic mixtures involving a drug: a rather general concept that can be utilized for prolonged drug release from gels.
Topics: Anions; Cations; Chemistry, Pharmaceutical; Cryoelectron Microscopy; Delayed-Action Preparations; Diffusion; Gels; Hydrogen-Ion Concentration; Ibuprofen; Kinetics; Lidocaine; Micelles; Orphenadrine; Pharmaceutical Preparations; Rheology; Sodium Dodecyl Sulfate; Solubility; Surface-Active Agents | 2006 |
Routine immunization practices: use of topical anesthetics and oral analgesics.
Topics: Acetaminophen; Administration, Oral; Administration, Topical; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Canada; Child; Child, Preschool; Cluster Analysis; Drug Utilization; Female; Humans; Ibuprofen; Interviews as Topic; Lidocaine; Linear Models; Male; Mothers; Pain; Practice Patterns, Physicians'; Prilocaine; Sampling Studies; Surveys and Questionnaires; Tetracaine; Vaccines | 2007 |
PLGA-based drug delivery systems: importance of the type of drug and device geometry.
Topics: Chemistry, Pharmaceutical; Delayed-Action Preparations; Diffusion; Drug Carriers; Drug Delivery Systems; Ibuprofen; Kinetics; Lactic Acid; Lidocaine; Microspheres; Models, Theoretical; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2008 |
Delayed retrobulbar haemorrhage associated with a repeat sub-Tenon's block.
Topics: Acetaminophen; Acetazolamide; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Cataract Extraction; Diagnosis, Differential; Diuretics; Edema; Eye; Female; Humans; Hyaluronoglucosaminidase; Ibuprofen; Lidocaine; Methylprednisolone; Middle Aged; Nerve Block; Postoperative Complications; Retrobulbar Hemorrhage; Tomography, X-Ray Computed; Visual Acuity | 2008 |
How to make screening mammography less uncomfortable.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Lidocaine; Mammography; Mass Screening; Middle Aged; Pain; Placebo Effect; Premedication; Treatment Outcome | 2008 |
Comment from the editor on Lambertz et al in the September 2008 issue.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Female; Humans; Ibuprofen; Lidocaine; Mammography; Mass Screening; Middle Aged; Pain; Placebo Effect; Premedication; Treatment Outcome | 2009 |
Drug release from PLGA-based microparticles: effects of the "microparticle:bulk fluid" ratio.
Topics: Buffers; Delayed-Action Preparations; Drug Delivery Systems; Hydrogen-Ion Concentration; Ibuprofen; Lactic Acid; Lidocaine; Membrane Fluidity; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Propranolol | 2010 |
Peculiar surface behavior of some ionic liquids based on active pharmaceutical ingredients.
Topics: Dioctyl Sulfosuccinic Acid; Ibuprofen; Ionic Liquids; Lidocaine; Pharmaceutical Preparations; Quaternary Ammonium Compounds; Ranitidine; Surface Tension; Temperature | 2011 |
Bacterial cellulose membranes applied in topical and transdermal delivery of lidocaine hydrochloride and ibuprofen: in vitro diffusion studies.
Topics: Administration, Cutaneous; Administration, Topical; Cellulose; Diffusion; Drug Delivery Systems; Humans; Ibuprofen; In Vitro Techniques; Lidocaine; Permeability; Skin | 2012 |
Impact of the experimental conditions on drug release from parenteral depot systems: From negligible to significant.
Topics: Dexamethasone; Drug Implants; Ibuprofen; Infusions, Parenteral; Kinetics; Lactic Acid; Lidocaine; Lipids; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prilocaine; Propranolol; Theophylline; X-Ray Diffraction | 2012 |
[Shingles symptoms are gone but not the pain].
Topics: Administration, Cutaneous; Administration, Oral; Aged; Amines; Amitriptyline; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Cyclohexanecarboxylic Acids; Dipyrone; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Guideline Adherence; Humans; Ibuprofen; Lidocaine; Neuralgia, Postherpetic; Phenols; Pregabalin; Tapentadol; Treatment Failure | 2015 |
Ionisation effects on the permeation of pharmaceutical compounds through silicone membrane.
Topics: Benzoic Acid; Chemistry, Pharmaceutical; Chromatography, Gas; Hydrogen-Ion Concentration; Ibuprofen; Ions; Ketoprofen; Lidocaine; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Silicon; Surface Properties; Triazoles | 2016 |
A case of severe NSAID exacerbated respiratory disease (NERD) following a dental procedure in a child.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Cyclooxygenase 2 Inhibitors; Drug Hypersensitivity; Dyspnea; Humans; Ibuprofen; Lidocaine; Male; Respiratory Sounds; Tooth Extraction | 2016 |
Unravelling the binding mechanism and protein stability of human serum albumin while interacting with nefopam analogues: a biophysical and insilico approach.
Topics: Analgesics, Non-Narcotic; Binding Sites; Binding, Competitive; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Kinetics; Lidocaine; Molecular Docking Simulation; Molecular Dynamics Simulation; Nefopam; Phenylbutazone; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Stability; Serum Albumin, Human; Solutions; Thermodynamics | 2017 |
Fabrication of non-dissolving analgesic suppositories using 3D printed moulds.
Topics: Analgesics; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diclofenac; Drug Liberation; Elastic Modulus; Ibuprofen; Ketoprofen; Lidocaine; Mice; Printing, Three-Dimensional; Silicone Elastomers; Solubility; Suppositories; Tensile Strength | 2016 |
pH-sensitive niosomes: Effects on cytotoxicity and on inflammation and pain in murine models.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; BALB 3T3 Cells; Cells, Cultured; Disease Models, Animal; Fibroblasts; Humans; Hydrogen-Ion Concentration; Ibuprofen; Inflammation; Lidocaine; Liposomes; Mice; Pain; Pain Measurement; Surface-Active Agents | 2017 |
Melting Process of the Peritectic Mixture of Lidocaine and Ibuprofen Interpreted by Site Percolation Theory Model.
Topics: Calorimetry, Differential Scanning; Hot Temperature; Ibuprofen; Kinetics; Lidocaine; Magnetic Resonance Spectroscopy; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman | 2017 |
Pharmacological advances in the multimodal management of perioperative analgesia.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Clinical Trials as Topic; Combined Modality Therapy; Dexmedetomidine; Drug Therapy, Combination; Humans; Ibuprofen; Ketamine; Lidocaine; Magnesium; Ondansetron; Pain Management; Pain, Postoperative; Pregabalin | 2017 |
Evaluation of local anesthetic effects of Lidocaine-Ibuprofen ionic liquid stabilized silver nanoparticles in Male Swiss mice.
Topics: Anesthetics; Animals; Ibuprofen; Ionic Liquids; Lidocaine; Male; Metal Nanoparticles; Mice; Microscopy, Electron, Transmission; Pain Threshold; Particle Size; Rats; Rats, Hairless; Silver; Spectrophotometry, Ultraviolet; X-Ray Diffraction | 2018 |
Selecting Excipients Forming Therapeutic Deep Eutectic Systems-A Mechanistic Approach.
Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallization; Drug Compounding; Drug Delivery Systems; Excipients; Humidity; Ibuprofen; Lidocaine; Phenylacetates; Solubility; Transition Temperature; Water | 2019 |
Revealing Intermolecular Hydrogen Bonding Structure and Dynamics in a Deep Eutectic Pharmaceutical by Magic-Angle Spinning NMR Spectroscopy.
Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Drug Combinations; Hydrogen; Hydrogen Bonding; Ibuprofen; Ionic Liquids; Lidocaine; Liquid Crystals; Magnetic Resonance Spectroscopy; Protons; Solvents; Temperature | 2020 |
Topical Drug Delivery Systems Based on Bacterial Nanocellulose: Accelerated Stability Testing.
Topics: Administration, Topical; Bacteria; Biocompatible Materials; Caffeine; Cellulose; Diclofenac; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Stability; Humans; Ibuprofen; Lidocaine; Nanoparticles | 2020 |
Enhancement of transdermal delivery of artemisinin using microemulsion vehicle based on ionic liquid and lidocaine ibuprofen.
Topics: Administration, Cutaneous; Animals; Artemisinins; Drug Carriers; Drug Delivery Systems; Emulsions; Ibuprofen; Ionic Liquids; Lidocaine; Mice; Molecular Conformation; Particle Size; Skin Absorption; Surface Properties | 2020 |
Applicability of capillary electrophoresis-frontal analysis for displacement studies: Effect of several drugs on l-tryptophan and lidocaine binding to human serum albumin.
Topics: Binding Sites; Chlorpropamide; Diclofenac; Electrophoresis, Capillary; Flurbiprofen; Humans; Ibuprofen; Lidocaine; Phenylbutazone; Serum Albumin, Human; Tolbutamide; Tryptophan | 2020 |
Use of Silicone Membrane Permeation to Assess Thermodynamic Activities of Ionic Liquids and Their Component Cation and Anion.
Topics: Anions; Cations; Ibuprofen; Ionic Liquids; Lidocaine; Molecular Structure; Silicones; Thermodynamics | 2021 |
Hard polymeric porous microneedles on stretchable substrate for transdermal drug delivery.
Topics: Administration, Cutaneous; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Carriers; Drug Compounding; Drug Delivery Systems; Drug Liberation; Hardness; Ibuprofen; Lidocaine; Miniaturization; Needles; Polymers; Porosity; Skin Absorption; Sus scrofa; Tensile Strength | 2022 |