ibuprofen has been researched along with leukotriene b4 in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (43.48) | 18.7374 |
| 1990's | 9 (39.13) | 18.2507 |
| 2000's | 4 (17.39) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, PB; Konstan, MW; Vargo, KM | 1 |
| Eberl, R; Partsch, G; Schwarzer, C | 1 |
| Fusco, AC; Salafsky, B; Whitely, K; Yohe, S | 1 |
| Docherty, JC; Wilson, TW | 1 |
| Jung, TT | 1 |
| Fusco, AC; Salafsky, B | 1 |
| Gordon, AH; Limãos, EA; Ribeiro, EB | 1 |
| Greaves, MW | 1 |
| Mandell, BF | 1 |
| Ferguson, MK; Michelassi, F; Shahinian, HK | 1 |
| Denzlinger, C; Hagmann, W; Keppler, D | 1 |
| Lefer, AM; Reibel, DK; Roth, DM | 1 |
| Rola-Pleszczynski, M; Thivierge, M | 1 |
| Heckenberger, R; Palmér, M; Schrör, K; Strobach, H; Villanueva, M | 1 |
| Hargreaves, KM; Hinrichs, JE; O'Brien, TP; Roszkowski, MT; Wolff, LF | 1 |
| De Lepeleire, I; De Schepper, PJ; Depré, M; Larson, P; Lin, C; Porras, A; Schwartz, J; Van Hecken, A; Verbesselt, R | 1 |
| Ghosh, J; Myers, CE | 1 |
| Degenhardt, V; Juergens, UR; Stöber, M; Vetter, H | 1 |
| Housholder, G; Hutchins, M; Montgomery, E; Rittman, B; Rittman, G; Suchina, J | 1 |
| Bagherzadeh, H; Unterhalt, B | 1 |
| Bikádi, Z; Lockwood, SF; Zsila, F | 1 |
| Barnes, PJ; Ciabattoni, G; Ciappi, G; Kharitonov, SA; Lauriola, L; Macagno, F; Montuschi, P; Parente, P; Valente, S | 1 |
| Daley, BJ; Enderson, BL; Gillis, RC; Karlstad, MD; Kestler, DP | 1 |
4 trial(s) available for ibuprofen and leukotriene b4
| Article | Year |
|---|---|
Effect of a non-steroidal anti-inflammatory drug on tissue levels of immunoreactive prostaglandin E2, immunoreactive leukotriene, and pain after periodontal surgery.
Topics: Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Dinoprostone; Double-Blind Method; Extracellular Space; Female; Humans; Ibuprofen; Immunoenzyme Techniques; Leukotriene B4; Male; Microdialysis; Middle Aged; Pain Measurement; Pain, Postoperative; Periodontitis; Periodontium; Prostaglandin Antagonists; Statistics, Nonparametric | 1996 |
Pharmacokinetic and pharmacodynamic interaction between the lipoxygenase inhibitor MK-0591 and the cyclooxygenase inhibitor ibuprofen in man.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Digestive System; Double-Blind Method; Drug Interactions; Drug Tolerance; Humans; Ibuprofen; Indoles; Kidney; Leukotriene B4; Leukotriene E4; Lipoxygenase Inhibitors; Male; Quinolines; Thromboxane B2 | 1998 |
New insights in the bronchodilatory and anti-inflammatory mechanisms of action of theophylline.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Bronchodilator Agents; Cyclic AMP; Cyclooxygenase Inhibitors; Dinoprostone; Drug Interactions; Female; Humans; Ibuprofen; Leukotriene B4; Lipopolysaccharides; Male; Monocytes; Stimulation, Chemical; Theophylline | 1999 |
Effects of cyclo-oxygenase inhibition on exhaled eicosanoids in patients with COPD.
Topics: Blood Gas Analysis; Cross-Over Studies; Cyclooxygenase Inhibitors; Dinoprostone; Double-Blind Method; Eicosanoids; Female; Forced Expiratory Volume; Humans; Ibuprofen; Lactones; Leukotriene B4; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Sputum; Sulfones; Thromboxane B2; Vital Capacity | 2005 |
19 other study(ies) available for ibuprofen and leukotriene b4
| Article | Year |
|---|---|
Ibuprofen attenuates the inflammatory response to Pseudomonas aeruginosa in a rat model of chronic pulmonary infection. Implications for antiinflammatory therapy in cystic fibrosis.
Topics: Animals; Body Weight; Chronic Disease; Cystic Fibrosis; Dinoprostone; Humans; Ibuprofen; Leukotriene B4; Lung; Lung Diseases; Neutrophils; Pseudomonas Infections; Rats | 1990 |
The effects of ibuprofen and diclofenac on the chemotaxis and adenosine triphosphate level of polymorphonuclear cells in vitro.
Topics: Adenosine Triphosphate; Cell Survival; Cells, Cultured; Chemotaxis, Leukocyte; Diclofenac; Humans; Ibuprofen; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Trypan Blue | 1990 |
Schistosoma mansoni: pH dependence of cercarial eicosanoid production, penetration, and transformation.
Topics: Agar; Animals; Eicosanoic Acids; Hydrogen-Ion Concentration; Hydroxyeicosatetraenoic Acids; Ibuprofen; In Vitro Techniques; Leukotriene B4; Morphogenesis; Movement; Prostaglandins; Schistosoma mansoni; SRS-A; Umbelliferones | 1987 |
Indomethacin increases the formation of lipoxygenase products in calcium ionophore stimulated human neutrophils.
Topics: Aspirin; Calcimycin; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; In Vitro Techniques; Indomethacin; Kinetics; Leukotriene B4; Lipoxygenase; Neutrophils; SRS-A | 1987 |
Prostaglandins, leukotrienes, and other arachidonic acid metabolites in the pathogenesis of otitis media.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Chinchilla; Dinoprostone; Disease Models, Animal; Humans; Hydrocortisone; Hydroxyeicosatetraenoic Acids; Ibuprofen; Leukotriene B4; Middle Ear Ventilation; Otitis Media with Effusion; Penicillin G; Prostaglandins; Prostaglandins E; SRS-A; Temporal Bone; Thromboxane B2 | 1988 |
Schistosoma mansoni: cercarial eicosanoid production and penetration response inhibited by esculetin and ibuprofen.
Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acids; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Hydroxyeicosatetraenoic Acids; Ibuprofen; Larva; Leukotriene B4; Linoleic Acid; Linoleic Acids; Lipoxygenase Inhibitors; Movement; Prostaglandins E; Radioimmunoassay; Schistosoma mansoni; Umbelliferones | 1985 |
Effect of endogenous pyrogen, corticosteroids and inhibitors of prostaglandins and leukotrienes on the plasma concentrations of haptoglobin and fibrinogen in rats.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adrenal Cortex Hormones; Adrenalectomy; Animals; Anti-Inflammatory Agents; Fibrinogen; Haptoglobins; Ibuprofen; Leukotriene B4; Male; Prostaglandin Antagonists; Pyrazoles; Pyrogens; Rats; Rats, Inbred Strains | 1985 |
Pharmacology and significance of nonsteroidal anti-inflammatory drugs in the treatment of skin diseases.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Dermatitis; Eicosanoic Acids; Humans; Ibuprofen; Leukotriene B4; Lipoxygenase Inhibitors; Propionates; Prostaglandins; Skin; Skin Diseases | 1987 |
Independent regulation of leukotriene B4-elicited polymorphonuclear leukocyte exocytosis and superoxide generation by a serum factor.
Topics: Exocytosis; Glucuronidase; Humans; Ibuprofen; Leukopenia; Leukotriene B4; Lupus Erythematosus, Systemic; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Stimulation, Chemical; Superoxides; Zymosan | 1987 |
Effects of leukotrienes B4, C4, and D4 on rat mesenteric microcirculation.
Topics: Acetophenones; Animals; Arterioles; Cell Adhesion; Endothelium; Ibuprofen; Leukotriene B4; Mesentery; Rats; Rats, Inbred Strains; Splanchnic Circulation; SRS-A; Tetrazoles; Vasoconstriction; Venules | 1987 |
Role of peptide leukotrienes and their hepatobiliary elimination in endotoxin action.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Bile; Chromones; Dexamethasone; Diethylcarbamazine; Endotoxins; Female; Ibuprofen; Indomethacin; Leukotriene B4; Liver; Metabolic Clearance Rate; Mice; Pyrazoles; Rats; Rats, Inbred Strains; Shock, Septic; SRS-A | 1984 |
Altered coronary vascular responsiveness to leukotrienes in alloxan-diabetic rats.
Topics: Aging; Animals; Blood Pressure; Coronary Circulation; Diabetes Mellitus, Experimental; Ibuprofen; Leukotriene B4; Male; Myocardial Contraction; Perfusion; Prostaglandin Antagonists; Rats; Rats, Inbred Strains; SRS-A; Vascular Resistance | 1984 |
Involvement of both cyclooxygenase and lipoxygenase pathways in platelet-activating factor-induced interleukin-6 production by alveolar macrophages.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Arachidonate 5-Lipoxygenase; Aspirin; Bucladesine; Cyclooxygenase Inhibitors; Dinoprostone; Ibuprofen; Indomethacin; Interleukin-6; Leukotriene B4; Macrophages, Alveolar; Male; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 1994 |
Equipotent inhibition by R(-)-, S(+)- and racemic ibuprofen of human polymorphonuclear cell function in vitro.
Topics: Blood Platelets; Cyclooxygenase Inhibitors; Glucuronidase; Humans; Ibuprofen; In Vitro Techniques; Leukotriene B4; Neutrophils; Platelet Aggregation; Stereoisomerism; Superoxides; Thromboxane B2 | 1993 |
Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Antineoplastic Agents; Apoptosis; Cell Membrane; Dietary Fats; Drug Combinations; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glycyrrhiza; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indoles; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mitochondria; Models, Biological; Nucleosomes; Oxidative Stress; Paeonia; Permeability; Phosphatidylserines; Prostatic Neoplasms; Tumor Cells, Cultured | 1998 |
Comparison of acetaminophen, ibuprofen, and nabumetone therapy in rats with pulpal pathosis.
Topics: Acetaminophen; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Dental Pulp Exposure; Dinoprostone; Ibuprofen; Leukotriene Antagonists; Leukotriene B4; Male; Nabumetone; Prostaglandin Antagonists; Rats; Rats, Wistar | 1999 |
[Nitramine analogues of ibuprofen].
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Cyclooxygenase Inhibitors; Ibuprofen; Leukotriene B4; Lipoxygenase Inhibitors; Rats | 2001 |
In vitro binding of leukotriene B4 (LTB4) to human serum albumin: evidence from spectroscopic, molecular modeling, and competitive displacement studies.
Topics: Binding Sites; Binding, Competitive; Circular Dichroism; Humans; Ibuprofen; Leukotriene B4; Ligands; Models, Molecular; Molecular Structure; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Serum Albumin; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 2005 |
Regulation of apoptosis in eicosapentaenoic acid-treated HL-60 cells.
Topics: Apoptosis; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Cyclooxygenase Inhibitors; Eicosapentaenoic Acid; Enzyme Inhibitors; Fatty Acids, Unsaturated; Flavanones; Guaiacol; HL-60 Cells; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indoles; Leukotriene B4; Lignans; Lipoxygenase Inhibitors; Neutrophils; Respiratory Distress Syndrome | 2007 |