ibuprofen and lactose

ibuprofen has been researched along with lactose in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.78)18.7374
1990's5 (13.89)18.2507
2000's13 (36.11)29.6817
2010's12 (33.33)24.3611
2020's5 (13.89)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Dwivedi, SK; Mitchell, AG; Oates, RJ1
Buchanan, WW; Downie, WW; Jasani, MK; Samuels, BM1
Jiabi, Z; Khan, GM1
Khan, GM; Zhu, JB1
Craig, DQ; Lever, TJ; Price, DM; Reading, M; Royall, PG1
Cox, PJ; Khan, KA; Munday, DL; Sujja-areevath, J1
Barra, J; Doelker, E; Falson-Rieg, F; Ullrich, A1
Hadgraft, J; Iervolino, M; Raghavan, SL1
Cappello, B; Hadgraft, J; Iervolino, M; Raghavan, SL1
Conde, C; Popo, M; Romañach, RJ; Romero-Torres, S1
Medvecká, G; Rabisková, M; Vostalová, L1
Costa, FO; Pais, AA; Sousa, JJ1
Dyas, AM; Fell, JT; Ford, JL; MacLeod, GS; Roberts, M; Rowe, PH; Smith, GW1
Conway, BR; Grattan, TJ; Irwin, WJ; Shaw, LR1
Dangor, CM; Lutchman, D; Perumal, D1
Knight, P; Podczeck, F1
Khan, GM; Meidan, VM1
Airaksinen, S; Antikainen, O; Lipsanen, T; Räikkönen, H; Yliruusi, J1
Knight, PE; Newton, JM; Podczeck, F1
Albertini, B; Calogerà, G; Passerini, N; Rodriguez, L1
Anwar, J; de Matas, M; Leusen, FJ; Shariare, MH; York, P1
Hu, DR; Ke, X; Tian, C; Tian, JL; Zhang, YL1
Mu, B; O'Donnell, KP; Sheskey, PJ; Thompson, MR; Weatherley, S1
Agarwal, K; Hicks, I; Kane, A; Kathiria, L; Kushner, J; Langdon, BA; Li, F; Ranade, G; Song, D1
Gorton, L; Knöös, P; Ludwig, R; Piculell, L; Schulz, C; Wahlgren, M1
Paul, S; Sun, CC1
Beránek, J; Dammer, O; Schöngut, M; Štěpánek, F; Tomas, J; Zadražil, A1
Emady, HN; Li, C; Zhang, L; Zhu, N1
Eda, T; Kagawa, Y; Miyazaki, Y; Uchino, T1
Ivone, R; Lin, X; Shen, J; Wang, X; Xie, L; Yang, G; Yang, Y1
Méndez, R; Romañach, RJ; Sierra-Vega, NO1
Gil-Chávez, J; Leopold, CS; Padhi, SSP; Smirnova, I1
Kagawa, Y; Miyazaki, Y; Uchino, T1

Trials

1 trial(s) available for ibuprofen and lactose

ArticleYear
Ibuprofen in rheumatoid arthritis. Clinical study of analgesic and anti-inflammatory activity.
    Annals of the rheumatic diseases, 1968, Volume: 27, Issue:5

    Topics: Adult; Aged; Alanine Transaminase; Arthritis, Rheumatoid; Aspartate Aminotransferases; Aspirin; Double-Blind Method; Female; Humans; Ibuprofen; Lactose; Male; Middle Aged; Pain; Prednisolone

1968

Other Studies

35 other study(ies) available for ibuprofen and lactose

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Peak offset times as an indication of stress relaxation during tableting on a rotary tablet press.
    The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:10

    Topics: Acetaminophen; Calcium Phosphates; Cellulose; Ibuprofen; Lactose; Pressure; Tablets; Technology, Pharmaceutical

1991
Formulation and in vitro evaluation of ibuprofen-Carbopol 974P-NF controlled release matrix tablets. III: Influence of co-excipients on release rate of the drug.
    Journal of controlled release : official journal of the Controlled Release Society, 1998, Jul-31, Volume: 54, Issue:2

    Topics: Acrylic Resins; Anti-Inflammatory Agents, Non-Steroidal; Cellulose; Delayed-Action Preparations; Drug Carriers; Excipients; Ibuprofen; In Vitro Techniques; Lactose; Polyvinyls; Solubility; Starch; Tablets

1998
Studies on drug release kinetics from ibuprofen-carbomer hydrophilic matrix tablets: influence of co-excipients on release rate of the drug.
    Journal of controlled release : official journal of the Controlled Release Society, 1999, Feb-01, Volume: 57, Issue:2

    Topics: Acrylic Resins; Cellulose; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Excipients; Hydrogen-Ion Concentration; Ibuprofen; Kinetics; Lactose; Models, Theoretical; Polyvinyls; Solubility; Starch; Tablets

1999
An investigation into the use of micro-thermal analysis for the solid state characterisation of an HPMC tablet formulation.
    International journal of pharmaceutics, 1999, Dec-01, Volume: 192, Issue:1

    Topics: Differential Thermal Analysis; Drug Compounding; Excipients; Ibuprofen; Lactose; Methylcellulose; Microscopy, Atomic Force; Oxazines; Tablets

1999
Development and evaluation of a multiple-unit oral sustained release dosage form for S(+)-ibuprofen: preparation and release kinetics.
    International journal of pharmaceutics, 1999, Dec-20, Volume: 193, Issue:1

    Topics: Capsules; Cellulose; Chemistry, Pharmaceutical; Delayed-Action Preparations; Excipients; Gelatin; Ibuprofen; In Vitro Techniques; Karaya Gum; Lactose; Methylcellulose; Oxazines; Polysaccharides, Bacterial; Statistics as Topic; Talc; Time Factors

1999
Color as an indicator of the organization and compactibility of binary powder mixes.
    Pharmaceutical development and technology, 2000, Volume: 5, Issue:1

    Topics: Cellulose; Color; Colorimetry; Ibuprofen; Lactose; Methylcellulose; Microscopy, Electron, Scanning; Niflumic Acid; Oxazines; Particle Size; Powders; Spectrum Analysis; Surface Properties; Tablets; Tensile Strength

2000
Membrane penetration enhancement of ibuprofen using supersaturation.
    International journal of pharmaceutics, 2000, Apr-05, Volume: 198, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Cyclodextrins; Diffusion; Drug Stability; Ibuprofen; Lactose; Methylcellulose; Oxazines; Permeability; Solubility

2000
Penetration enhancement of ibuprofen from supersaturated solutions through human skin.
    International journal of pharmaceutics, 2001, Jan-05, Volume: 212, Issue:1

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Crystallization; Cyclodextrins; Diffusion; Humans; Ibuprofen; Lactose; Methylcellulose; Oxazines; Skin

2001
Blend uniformity analysis using stream sampling and near infrared spectroscopy.
    AAPS PharmSciTech, 2002, Volume: 3, Issue:3

    Topics: Calibration; Chemistry, Pharmaceutical; Ibuprofen; Lactose; Models, Chemical; Powders; Reference Standards; Spectroscopy, Near-Infrared; Technology, Pharmaceutical

2002
[Release of diltiazem chloride and ibuprofen from hydrophilic matrix tablets].
    Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 2003, Volume: 52, Issue:6

    Topics: Cardiovascular Agents; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diltiazem; Ibuprofen; Lactose; Methylcellulose; Oxazines; Solubility; Tablets

2003
Analysis of formulation effects in the dissolution of ibuprofen pellets.
    International journal of pharmaceutics, 2004, Feb-11, Volume: 270, Issue:1-2

    Topics: Calcium Phosphates; Chemistry, Pharmaceutical; Citric Acid; Compressive Strength; Excipients; Hydrogen-Ion Concentration; Ibuprofen; Lactose; Microscopy, Electron, Scanning; Porosity; Solubility; Surface Properties; Tablets

2004
Effect of punch tip geometry and embossment on the punch tip adherence of a model ibuprofen formulation.
    The Journal of pharmacy and pharmacology, 2004, Volume: 56, Issue:7

    Topics: Adhesiveness; Compressive Strength; Ibuprofen; Lactose; Tablets; Technology, Pharmaceutical

2004
The effect of selected water-soluble excipients on the dissolution of paracetamol and Ibuprofen.
    Drug development and industrial pharmacy, 2005, Volume: 31, Issue:6

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Bicarbonates; Buffers; Drug Implants; Excipients; Gastrointestinal Tract; Humans; Hydrogen-Ion Concentration; Ibuprofen; Lactose; Models, Biological; Potassium Compounds; Sodium Bicarbonate; Sodium Chloride; Solubility; Tartrates; Technology, Pharmaceutical; Viscosity; Water

2005
Formulation of rate-modulating pellets for the release of ibuprofen: an extrusion-spheronization process.
    Journal of microencapsulation, 2005, Volume: 22, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cellulose; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Delivery Systems; Drug Implants; Drug Stability; Humans; Hydrogen-Ion Concentration; Ibuprofen; Lactose; Methylcellulose; Microscopy, Electron, Scanning; Models, Chemical; Particle Size; Polymethacrylic Acids; Viscosity

2005
The evaluation of formulations for the preparation of pellets with high drug loading by extrusion/spheronization.
    Pharmaceutical development and technology, 2006, Volume: 11, Issue:3

    Topics: Ascorbic Acid; Buffers; Cellulose; Chemistry, Pharmaceutical; Drug Implants; Evaluation Studies as Topic; Hydrogen-Ion Concentration; Ibuprofen; Lactose; Particle Size; Powders; Rheology; Solubility; Technology, Pharmaceutical; Water

2006
Drug release kinetics from tablet matrices based upon ethylcellulose ether-derivatives: a comparison between different formulations.
    Drug development and industrial pharmacy, 2007, Volume: 33, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cellulose; Chemistry, Pharmaceutical; Delayed-Action Preparations; Ethers; Excipients; Ibuprofen; Kinetics; Lactose; Methylcellulose; Particle Size; Solubility; Tablets; Viscosity

2007
Effect of fluidisation activity on end-point detection of a fluid bed drying process.
    International journal of pharmaceutics, 2008, Jun-05, Volume: 357, Issue:1-2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Desiccation; Drug Compounding; Excipients; Humidity; Ibuprofen; Indicators and Reagents; Lactose; Povidone; Powders; Temperature

2008
The rheological properties of modified microcrystalline cellulose containing high levels of model drugs.
    Journal of pharmaceutical sciences, 2009, Volume: 98, Issue:6

    Topics: Ascorbic Acid; Carboxymethylcellulose Sodium; Cellulose; Elasticity; Excipients; Ibuprofen; Lactose; Pressure; Rheology; Stress, Mechanical; Viscosity; Water

2009
Melt granulation of pharmaceutical powders: a comparison of high-shear mixer and fluidised bed processes.
    International journal of pharmaceutics, 2010, May-31, Volume: 391, Issue:1-2

    Topics: Compressive Strength; Drug Compounding; Drug Stability; Drug Storage; Ibuprofen; Lactose; Particle Size; Polyethylene Glycols; Porosity; Powders; Rheology; Solubility; Temperature

2010
Prediction of the mechanical behaviour of crystalline solids.
    Pharmaceutical research, 2012, Volume: 29, Issue:1

    Topics: Acetaminophen; Albuterol; Anisotropy; Chromatography, Gas; Crystallization; Ibuprofen; Lactose; Particle Size; Powders; Stress, Mechanical; Surface Properties; Thermodynamics

2012
[Micromeritic evaluation of the direct compression excipient LubriTose AN].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2012, Volume: 47, Issue:5

    Topics: Drug Compounding; Elasticity; Excipients; Glycerides; Ibuprofen; Lactose; Lubricants; Lubrication; Particle Size; Pressure; Technology, Pharmaceutical; Tensile Strength

2012
Hot-melt granulation in a twin screw extruder: effects of processing on formulations with caffeine and Ibuprofen.
    Journal of pharmaceutical sciences, 2013, Volume: 102, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Drug Compounding; Drug Stability; Hot Temperature; Ibuprofen; Lactose; Particle Size; Solubility; X-Ray Diffraction

2013
A quality-by-design study for an immediate-release tablet platform: examining the relative impact of active pharmaceutical ingredient properties, processing methods, and excipient variability on drug product quality attributes.
    Journal of pharmaceutical sciences, 2014, Volume: 103, Issue:2

    Topics: Carboxymethylcellulose Sodium; Cellulose; Chemistry, Pharmaceutical; Drug Compounding; Excipients; Hardness; Ibuprofen; Lactose; Lubricants; Particle Size; Powders; Pressure; Solubility; Stearic Acids; Tablets; Theophylline

2014
Quantifying the release of lactose from polymer matrix tablets with an amperometric biosensor utilizing cellobiose dehydrogenase.
    International journal of pharmaceutics, 2014, Jul-01, Volume: 468, Issue:1-2

    Topics: Acrylates; Biosensing Techniques; Carbohydrate Dehydrogenases; Excipients; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Imines; Kinetics; Lactose; Polyethylenes; Polymers; Quaternary Ammonium Compounds; Sodium Dodecyl Sulfate; Solubility; Surface-Active Agents; Tablets; Technology, Pharmaceutical

2014
The suitability of common compressibility equations for characterizing plasticity of diverse powders.
    International journal of pharmaceutics, 2017, Oct-30, Volume: 532, Issue:1

    Topics: Algorithms; Calcium Phosphates; Celecoxib; Cellulose; Compressive Strength; Excipients; Hardness; Ibuprofen; Lactose; Mannitol; Powders; Stearic Acids

2017
Probing the early stages of tablet disintegration by stress relaxation measurement.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018, Nov-01, Volume: 124

    Topics: Excipients; Hydrogen-Ion Concentration; Ibuprofen; Lactose; Stress, Mechanical; Tablets; Tensile Strength

2018
Synchrotron-based X-ray in-situ imaging techniques for advancing the understanding of pharmaceutical granulation.
    International journal of pharmaceutics, 2019, Dec-15, Volume: 572

    Topics: Acetaminophen; Carboxymethylcellulose Sodium; Cellulose; Drug Compounding; Excipients; Humans; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Lactose; Molecular Imaging; Particle Size; Powders; Synchrotrons; Technology, Pharmaceutical; X-Rays

2019
Small-Scale Spherical Granulation Using a Planetary Centrifugal Mixer.
    Chemical & pharmaceutical bulletin, 2020, Volume: 68, Issue:3

    Topics: Calorimetry, Differential Scanning; Centrifugation; Ibuprofen; Lactose; Mannitol; Particle Size; Powder Diffraction; Starch; Surface Properties

2020
A tunable extruded 3D printing platform using thermo-sensitive pastes.
    International journal of pharmaceutics, 2020, Jun-15, Volume: 583

    Topics: Cellulose; Delayed-Action Preparations; Diclofenac; Excipients; Gelatin; Glycerol; Hydrodynamics; Hypromellose Derivatives; Ibuprofen; Lactose; Mannitol; Printing, Three-Dimensional; Rheology; Technology, Pharmaceutical; Viscosity; Water

2020
Real-time quantification of low-dose cohesive formulations within a sampling interface for flowing powders.
    International journal of pharmaceutics, 2020, Oct-15, Volume: 588

    Topics: Cellulose; Drug Compounding; Excipients; Ibuprofen; Lactose; Particle Size; Powders; Quality Control; Spectroscopy, Near-Infrared; Stearic Acids; Technology, Pharmaceutical

2020
Application of Aquasolv Lignin in ibuprofen-loaded pharmaceutical formulations obtained via direct compression and wet granulation.
    International journal of biological macromolecules, 2021, Mar-31, Volume: 174

    Topics: Cellulose; Drug Carriers; Drug Compounding; Drug Dosage Calculations; Excipients; Ibuprofen; Lactose; Legislation, Drug; Lignin; Tablets; Wettability

2021
Effect of batch size on the granule properties in planetary centrifugal granulation.
    Die Pharmazie, 2022, 04-10, Volume: 77, Issue:3

    Topics: Drug Compounding; Ibuprofen; Lactose; Particle Size; Powders; Starch

2022