ibuprofen has been researched along with lactic acid in 67 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.49) | 18.7374 |
| 1990's | 7 (10.45) | 18.2507 |
| 2000's | 14 (20.90) | 29.6817 |
| 2010's | 42 (62.69) | 24.3611 |
| 2020's | 3 (4.48) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Drew, R; Knights, KM | 1 |
| Pinsky, MR | 1 |
| Apstein, CS; Vogel, WM | 1 |
| Jimenez, AE; Passmore, JC | 1 |
| Buxton, DB; Halvorsen, O; Olson, MS; Zhou, W | 1 |
| Arcos, D; Cabañas, MV; Doadrio, AL; Gordo, M; Granado, S; Ragel, CV; Salinas, AJ; San Román, J; Vallet-Regí, M | 1 |
| Eguiburu, JL; Fernandez Berridi, MJ; Gallardo, A; San Román, J | 1 |
| Ikeda, M; Koshika, A; Miyajima, M; Okada, J | 1 |
| Hauser, PC; Tanyanyiwa, J | 1 |
| Ladrón de Guevara-Fernández, S; Ragel, CV; Vallet-Regí, M | 1 |
| Chang, MH; Charron, FM; Coady, MJ; Lapointe, JY; Markowitz, SD; Plata, C; Romero, MF; Sah, JF; Wallendorff, B | 1 |
| Fernández-Carballido, A; Herrero-Vanrell, R; Molina-Martínez, IT; Pastoriza, P | 2 |
| Nicoli, S; Santi, P; Sebastiani, P | 1 |
| Dan, N; Kahn, JB; Metzger, K; Siegel, SJ; Werner, K; Winey, KI | 1 |
| Elkharraz, K; Klose, D; Siepmann, F; Siepmann, J | 1 |
| Depan, D; Kumar, AP; Singh, RP | 1 |
| Gravel, A; Pedro, DF; Vijayan, MM; Wilson, JM | 1 |
| Deng, L; Dong, A; Du, H; Liu, Z; Xing, J; Zeng, Y; Zhang, J | 1 |
| Baruch, L; Ben Itzhak, O; Benny, O; Gilert, A; Machluf, M; Ukobnik, M | 1 |
| El Ghazouani, F; Emond, E; Lamprecht, A; Maincent, P; Sapin, A; Sheikh Hassan, A | 1 |
| Descamps, M; Klose, D; Siepmann, F; Siepmann, J; Willart, JF | 1 |
| Lamprecht, A; Merkwirth, C; Neumann, D | 1 |
| Bruinewoud, H; Gabriel, AF; Hoogenboom, R; Joosten, EA; Kemmere, MF; Keurentjes, JT; Marcus, MA; Péters, FL; Rovers, SA; Stemkens, LF; Tielen, NJ; van Asseldonk, DT; Vertommen, MA | 1 |
| Chen, YY; Wang, XL; Wang, YZ | 1 |
| Dyson, KS; Faisal, A; Hughson, RL | 1 |
| Delplace, C; Klose, D; Siepmann, J | 1 |
| Chen, YD; Guan, FY; Lin, YL; Tan, WA; Wang, LS; Zhang, AQ | 1 |
| Lee, WL; Loei, C; Loo, SC; Widjaja, E | 1 |
| Jin, Y; Ma, FW; Ni, CH; Zhang, WF; Zhou, SB | 1 |
| Cai, X; Du, J; Li, F; Li, Z; Luan, Y; Pang, J | 1 |
| Hong, M; Lee, WL; Loo, SC; Widjaja, E; Yu, PO | 1 |
| Danède, F; Delplace, C; Descamps, M; Klose, D; Kreye, F; Siepmann, F; Siepmann, J | 1 |
| Lee, WL; Li, S; Loo, SC; Low, ZY; Shi, WX | 1 |
| Cui, W; Fan, C; Hu, C; Li, F; Li, XJ; Liu, S | 1 |
| Arra, C; Bonelli, P; Borrelli, A; Carinci, F; Federico, A; Melisi, D; Napolitano, M; Palaia, R; Rimoli, MG; Tuccillo, FM | 1 |
| Eppacher, S; Kruse, J; Lachmann, B; Lauer, R; Noe, CR | 1 |
| Jia, H; Kerr, LL | 1 |
| Luo, R; Neu, B; Venkatraman, SS | 1 |
| Choi, SY; Choy, YB; Heo, CY; Kim, BH; Kim, MH; Lee, JE; Lee, SH; Park, CG; Park, HJ; Park, JH; Park, M; Park, S | 1 |
| Arias, ML; Boemo, RL; Carreras, N; Immich, AP; Tornero, JA | 1 |
| Dvořáčkov, K; Kejdušová, M; Vetchý, D; Vysloužil, J | 1 |
| Bédouet, L; Labarre, D; Laurent, A; Moine, L; Nguyen, VN; Pascale, F | 1 |
| Ben-Gal, TS; Gilboa, E; Shemesh, M; Zilberman, M | 1 |
| Shemesh, M; Zilberman, M | 1 |
| Baldino, L; Cardea, S; Reverchon, E; Scognamiglio, M | 1 |
| Chang, J; Shi, M; Wu, C; Zhai, D; Zhao, L | 1 |
| Chen, Y; Cui, W; Yang, Z; Yuan, Z; Zhao, J; Zheng, Q | 1 |
| Bian, C; Han, X; Li, X; Lin, H; Ma, J; Qu, F; Wu, X; Xiang, D | 1 |
| Chen, W; Hu, Y; Tong, Z; Wang, C; Zou, S | 1 |
| Chen, W; Gu, X; Hu, M; Hu, Y; Huang, J; Tong, Z; Wang, C; Yang, Y | 1 |
| Doležel, P; Dvořáčková, K; Kejdušová, M; Košťál, V; Lukáč, R; Mašek, J; Mašková, E; Vetchý, D; Vysloužil, J | 1 |
| Ding, Y; He, F; Ni, C; Shi, G; Wu, L; Zhang, X | 1 |
| Du, Z; Hu, Y; Huang, J; Ma, S; Wang, C; Yang, Z; Yi, H; Zhou, W | 1 |
| Gheibi, N; Jamshidi-Adegani, F; Sahmani, M; Seyedjafari, E; Soleimani, M | 1 |
| Ghannoum, M; Gosselin, S; Grunbaum, AM; Kazim, S; Villeneuve, E | 1 |
| Calpena, AC; Camins, A; Cano, A; Egea, MA; Espina, M; Ettcheto, M; García, ML; Sánchez-López, E; Silva, AM; Souto, EB | 1 |
| Bernstein, J; Huegel, J; Kim, DH; Kuntz, AF; Mauck, RL; Qu, F; Riggin, CN; Soslowsky, LJ; Steinberg, DR | 1 |
| Feng, J; Huang, S; Shang, Q; Yang, S; Zhang, A | 1 |
| Klanke, C; Luebbert, C; Sadowski, G | 1 |
| Araújo, F; Bermejo, M; González-Álvarez, I; González-Álvarez, M; Lozoya-Agullo, I; Merino-Sanjuán, M; Sarmento, B | 1 |
| Akbas, S; Aktas, Y; Arslan, FB; Capan, Y; Colak, N; Guedon, I; Ozdemir, B; Ozdemir, S; Ozkan, T; Sahin, A; Sarcan, ET; Spiroux, F; Ultav, G; Yuksel, S | 1 |
| Lewitus, DY; Shpigel, T; Uziel, A | 1 |
| Fujita, T; Kono, Y; Yuri, T | 1 |
| Al-Thamarani, S; Gardouh, A | 1 |
| Al-Mousa, AA; Alsalem, MI; Altarifi, AA; Neubert, JK; Nuseir, KQ; Qaoud, AK; Younis, BA | 1 |
67 other study(ies) available for ibuprofen and lactic acid
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
The effects of ibuprofen enantiomers on hepatocyte intermediary metabolism and mitochondrial respiration.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Hydroxybutyrates; Ibuprofen; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Mitochondria, Liver; Oxidative Phosphorylation; Oxygen Consumption; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Stereoisomerism | 1992 |
Cardiovascular response in canine endotoxic shock: effect of ibuprofen pretreatment.
Topics: Acidosis; Animals; Disease Models, Animal; Dogs; Hemodynamics; Ibuprofen; Lactates; Lactic Acid; Oxygen Consumption; Shock, Septic; Vascular Resistance | 1992 |
Coronary arterial vasodilator effect of ibuprofen.
Topics: Adenosine; Animals; Coronary Vessels; Ibuprofen; In Vitro Techniques; Lactates; Lactic Acid; Myocardium; Oxygen; Rabbits; Vascular Resistance; Vasodilator Agents | 1982 |
Effectiveness of dual cyclooxygense and leukotriene blockade with ibuprofen and LY203647 during canine endotoxic shock.
Topics: Acetophenones; Acid-Base Equilibrium; Animals; Aspartate Aminotransferases; Blood Glucose; Blood Pressure; Dogs; Glomerular Filtration Rate; Ibuprofen; Lactates; Lactic Acid; Renal Circulation; Shock, Septic; SRS-A; Tetrazoles | 1993 |
Glycogenolytic and haemodynamic responses to bovine serum albumin in isolated perfused livers from sensitized rats.
Topics: Animals; Azepines; Calcium; Glycogen; Hemodynamics; Ibuprofen; In Vitro Techniques; Indomethacin; Lactates; Lactic Acid; Liver; Male; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Triazoles | 1993 |
Preparation, characterization, and in vitro release of ibuprofen from AI2O3/PLA/PMMA composites.
Topics: Aluminum Oxide; Anti-Inflammatory Agents, Non-Steroidal; Biocompatible Materials; Buffers; Chromatography, High Pressure Liquid; Composite Resins; Ibuprofen; Indicators and Reagents; Lactic Acid; Magnetic Resonance Spectroscopy; Polyesters; Polymers; Polymethyl Methacrylate; Spectrophotometry, Ultraviolet; Stereoisomerism | 1998 |
Preparation and in vitro release studies of ibuprofen-loaded films and microspheres made from graft copolymers of poly(L-lactic acid) on acrylic backbones.
Topics: Acrylates; Anti-Inflammatory Agents, Non-Steroidal; Drug Carriers; Hydrolysis; Ibuprofen; Lactic Acid; Magnetic Resonance Spectroscopy; Microscopy, Electron, Scanning; Microspheres; Polyesters; Polymers; Spectrophotometry, Ultraviolet | 1998 |
Mechanism of drug release from poly(L-lactic acid) matrix containing acidic or neutral drugs.
Topics: Biodegradation, Environmental; Crystallization; Delayed-Action Preparations; Diffusion; Griseofulvin; Hydrogen-Ion Concentration; Ibuprofen; Indomethacin; Lactic Acid; Naproxen; Polymers; Progesterone; Solubility; Testosterone | 1999 |
High-voltage capacitively coupled contactless conductivity detection for microchip capillary electrophoresis.
Topics: Acetaminophen; Citric Acid; Electric Conductivity; Electrodes; Electrophoresis, Capillary; Ibuprofen; Lactic Acid; Metals, Heavy; Salicylic Acid; Sensitivity and Specificity | 2002 |
Bioactive glass-polymer materials for controlled release of ibuprofen.
Topics: Apatites; Biocompatible Materials; Calcium; Glass; Ibuprofen; Ions; Kinetics; Lactic Acid; Microscopy, Electron, Scanning; Polyesters; Polymers; Polymethyl Methacrylate; Temperature; Time Factors; X-Ray Diffraction | 2003 |
The human tumour suppressor gene SLC5A8 expresses a Na+-monocarboxylate cotransporter.
Topics: Animals; Carboxylic Acids; Cation Transport Proteins; Cell Membrane; Colon; Colonic Neoplasms; Cyclooxygenase Inhibitors; Fatty Acids, Volatile; Humans; Hydrogen-Ion Concentration; Ibuprofen; Kinetics; Lactic Acid; Membrane Potentials; Microelectrodes; Monocarboxylic Acid Transporters; Oocytes; Patch-Clamp Techniques; RNA, Messenger; Sodium; Symporters; Xenopus laevis | 2004 |
Biodegradable ibuprofen-loaded PLGA microspheres for intraarticular administration. Effect of Labrafil addition on release in vitro.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Ibuprofen; Injections, Intra-Articular; Lactic Acid; Microspheres; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility; Surface Properties | 2004 |
Effect of lactic acid and iontophoresis on drug permeation across rabbit ear skin.
Topics: Acetaminophen; Administration, Topical; Animals; Biological Availability; Buspirone; Cell Membrane Permeability; Drug Evaluation, Preclinical; Ear; Excipients; Ibuprofen; Iontophoresis; Lactic Acid; Lysine; Rabbits; Skin Absorption | 2005 |
Sterilized ibuprofen-loaded poly(D,L-lactide-co-glycolide) microspheres for intra-articular administration: effect of gamma-irradiation and storage.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biocompatible Materials; Calorimetry, Differential Scanning; Chromatography, Gel; Delayed-Action Preparations; Drug Compounding; Drug Delivery Systems; Drug Storage; Gamma Rays; Humans; Ibuprofen; Knee Joint; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Sterilization; Surface Properties; X-Ray Diffraction | 2004 |
Effect of drug type on the degradation rate of PLGA matrices.
Topics: Anti-Inflammatory Agents; Antipsychotic Agents; Aspirin; Biocompatible Materials; Corticosterone; Delayed-Action Preparations; Diffusion; Drug Carriers; Haloperidol; Hydrochlorothiazide; Hydrolysis; Ibuprofen; Kinetics; Lactic Acid; Models, Chemical; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility; Thiothixene; Time Factors | 2006 |
PLGA-based drug delivery systems: importance of the type of drug and device geometry.
Topics: Chemistry, Pharmaceutical; Delayed-Action Preparations; Diffusion; Drug Carriers; Drug Delivery Systems; Ibuprofen; Kinetics; Lactic Acid; Lidocaine; Microspheres; Models, Theoretical; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2008 |
Cell proliferation and controlled drug release studies of nanohybrids based on chitosan-g-lactic acid and montmorillonite.
Topics: Bentonite; Biocompatible Materials; Cell Proliferation; Chitosan; Drug Delivery Systems; HL-60 Cells; Humans; Ibuprofen; Lactic Acid; Nanostructures; Nanotechnology; Stress, Mechanical; Tensile Strength; Tissue Engineering; X-Ray Diffraction | 2009 |
Non-steroidal anti-inflammatory drugs disturb the osmoregulatory, metabolic and cortisol responses associated with seawater exposure in rainbow trout.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; Gills; Glycolysis; Hydrocortisone; Ibuprofen; Immunohistochemistry; Lactic Acid; Liver; Liver Glycogen; Oncorhynchus mykiss; Receptors, Glucocorticoid; Salicylates; Seawater; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Water-Electrolyte Balance | 2009 |
A novel hydrophilic adhesive matrix with self-enhancement for drug percutaneous permeation through rat skin.
Topics: Adhesives; Administration, Cutaneous; Analgesics, Non-Narcotic; Animals; Anti-Infective Agents; Drug Delivery Systems; Drug Stability; Glycerol; Ibuprofen; Lactic Acid; Povidone; Pressure; Rats; Salicylic Acid; Skin; Water | 2009 |
Alginate-PLL cell encapsulation system Co-entrapping PLGA-microspheres for the continuous release of anti-inflammatory drugs.
Topics: Alginates; Animals; Anti-Inflammatory Agents; Capsules; Cell Line; Cell Survival; Cricetinae; Delayed-Action Preparations; Drug Carriers; Feasibility Studies; Glucuronic Acid; Hexuronic Acids; Ibuprofen; Lactic Acid; Male; Materials Testing; Mice; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polylysine | 2009 |
Composite microparticles with in vivo reduction of the burst release effect.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Injections, Subcutaneous; Lactic Acid; Male; Microspheres; Nanoparticles; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Wistar | 2009 |
Drug release from PLGA-based microparticles: effects of the "microparticle:bulk fluid" ratio.
Topics: Buffers; Delayed-Action Preparations; Drug Delivery Systems; Hydrogen-Ion Concentration; Ibuprofen; Lactic Acid; Lidocaine; Membrane Fluidity; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Propranolol | 2010 |
Nanoparticle design characterized by in silico preparation parameter prediction using ensemble models.
Topics: Analgesics, Non-Narcotic; Drug Carriers; Ibuprofen; Lactic Acid; Models, Statistical; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymethacrylic Acids; Solvents | 2010 |
Externally triggered glass transition switch for localized on-demand drug delivery.
Topics: Analgesics, Non-Narcotic; Animals; Coloring Agents; Drug Delivery Systems; Glass; Ibuprofen; Infrared Rays; Lactic Acid; Male; Polyesters; Polymers; Rats; Rats, Sprague-Dawley | 2009 |
Synthesis of poly(p-dioxanone) catalyzed by Zn L-lactate under microwave irradiation and its application in ibuprofen delivery.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Catalysis; Dioxanes; Drug Carriers; Ibuprofen; Lactic Acid; Microwaves; Polymers; Zinc | 2010 |
Prolonged ischaemia impairs muscle blood flow and oxygen uptake dynamics during subsequent heavy exercise.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Blood Pressure; Brachial Artery; Carbon Dioxide; Exercise; Forearm; Hand Strength; Humans; Ibuprofen; Ischemia; Kinetics; Lactic Acid; Male; Muscle, Skeletal; Oxygen Consumption; Physical Fitness; Regional Blood Flow; Young Adult | 2010 |
Unintended potential impact of perfect sink conditions on PLGA degradation in microparticles.
Topics: Calorimetry, Differential Scanning; Carbamazepine; Chemistry, Pharmaceutical; Chromatography, Gel; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Hydrogen-Ion Concentration; Ibuprofen; Kinetics; Lactic Acid; Microscopy, Electron, Scanning; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Solubility; Technology, Pharmaceutical; Transition Temperature | 2011 |
[Preparation of ibuprofen/sPEG-b-PLLA copolymer microspheres and its in vitro release properties].
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Drug Carriers; Ibuprofen; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Microspheres; Particle Size; Polyesters; Polyethylene Glycols; Polymers; Spectroscopy, Fourier Transform Infrared | 2010 |
Altering the drug release profiles of double-layered ternary-phase microparticles.
Topics: Chromatography, Gel; Drug Carriers; Drug Compounding; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Lactic Acid; Metoclopramide; Microscopy, Electron, Scanning; Molecular Weight; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility; Spectrum Analysis, Raman; Surface Properties | 2011 |
[Drug release properties of sodium alginate hydrophobically modified by star polylactic acid].
Topics: Alginates; Biocompatible Materials; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Glucuronic Acid; Hexuronic Acids; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Nanostructures; Polyesters; Polymers | 2010 |
Ibuprofen-loaded poly(lactic-co-glycolic acid) films for controlled drug release.
Topics: Calorimetry, Differential Scanning; Delayed-Action Preparations; Drug Delivery Systems; Ibuprofen; Kinetics; Lactic Acid; Microscopy, Electron, Scanning; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Powder Diffraction | 2011 |
Designing multilayered particulate systems for tunable drug release profiles.
Topics: Calorimetry, Differential Scanning; Chromatography, Gel; Ibuprofen; Lactic Acid; Microscopy, Electron, Scanning; Molecular Weight; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyls; Spectrum Analysis, Raman | 2012 |
Impact of the experimental conditions on drug release from parenteral depot systems: From negligible to significant.
Topics: Dexamethasone; Drug Implants; Ibuprofen; Infusions, Parenteral; Kinetics; Lactic Acid; Lidocaine; Lipids; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prilocaine; Propranolol; Theophylline; X-Ray Diffraction | 2012 |
Modeling of drug release from biodegradable triple-layered microparticles.
Topics: Biocompatible Materials; Biodegradation, Environmental; Diffusion; Drug Delivery Systems; Ibuprofen; Lactic Acid; Models, Chemical; Molecular Weight; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyls; Time Factors | 2012 |
Prevention of peritendinous adhesions with electrospun ibuprofen-loaded poly(L-lactic acid)-polyethylene glycol fibrous membranes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bandages; Chickens; Diffusion; Drug Implants; Electrochemistry; Ibuprofen; Lactic Acid; Membranes, Artificial; Polyesters; Polyethylene; Polymers; Porosity; Rotation; Tenotomy; Tissue Adhesions; Treatment Outcome | 2013 |
Ibuprofen delivered by poly(lactic-co-glycolic acid) (PLGA) nanoparticles to human gastric cancer cells exerts antiproliferative activity at very low concentrations.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Ibuprofen; Lactic Acid; Nanocapsules; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Stomach Neoplasms; Treatment Outcome | 2012 |
Lactic acid oligomers (OLAs) as prodrug moieties.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Buffers; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Humans; Ibuprofen; Indicators and Reagents; Isomerism; Lactic Acid; Polyethylene Glycols; Prodrugs; Protein Binding | 2013 |
Sustained ibuprofen release using composite poly(lactic-co-glycolic acid)/titanium dioxide nanotubes from Ti implant surface.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Ibuprofen; Lactic Acid; Nanotubes; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prostheses and Implants; Tensile Strength; Titanium | 2013 |
Layer-by-layer polyelectrolyte-polyester hybrid microcapsules for encapsulation and delivery of hydrophobic drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcium Carbonate; Capsules; Drug Carriers; Electrolytes; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Lactic Acid; Magnetite Nanoparticles; Particle Size; Polyamines; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polystyrenes; Pyrrolidinones | 2013 |
Surgical suture assembled with polymeric drug-delivery sheet for sustained, local pain relief.
Topics: Analgesics; Animals; Delayed-Action Preparations; Diffusion; Equipment Design; Equipment Failure Analysis; Ibuprofen; Lactic Acid; Male; Materials Testing; Pain Measurement; Pain, Postoperative; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Sutures; Tensile Strength; Treatment Outcome; Wound Closure Techniques | 2013 |
Drug delivery systems using sandwich configurations of electrospun poly(lactic acid) nanofiber membranes and ibuprofen.
Topics: Cell Survival; Drug Delivery Systems; HeLa Cells; Humans; Ibuprofen; Kinetics; Lactic Acid; Membranes, Artificial; Nanofibers; Polyesters; Polymers; Time Factors; Toxicity Tests | 2013 |
Influence of formulation and process parameters on the characteristics of PLGA-based microparticles with controlled drug release.
Topics: Acetates; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Liberation; Ibuprofen; Lactic Acid; Methylene Chloride; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solvents | 2013 |
Synthesis of hydrophilic intra-articular microspheres conjugated to ibuprofen and evaluation of anti-inflammatory activity on articular explants.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Delayed-Action Preparations; Dialysis; Dinoprostone; Hydrolysis; Ibuprofen; Injections, Intra-Articular; L-Lactate Dehydrogenase; Lactic Acid; Lipopolysaccharides; Magnetic Resonance Spectroscopy; Microspheres; Organ Culture Techniques; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prostaglandin-Endoperoxide Synthases; Sheep; Synovial Membrane | 2014 |
Controlled release of analgesic drugs from porous bioresorbable structures for various biomedical applications.
Topics: Analgesics; Biocompatible Materials; Bupivacaine; Delayed-Action Preparations; Drug Delivery Systems; Emulsions; Ibuprofen; Lactic Acid; Microscopy, Electron, Scanning; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Surface-Active Agents; Tissue Engineering | 2014 |
Structure-property effects of novel bioresorbable hybrid structures with controlled release of analgesic drugs for wound healing applications.
Topics: Absorption, Physicochemical; Analgesics; Animals; Biocompatible Materials; Bupivacaine; Cryoelectron Microscopy; Delayed-Action Preparations; Ibuprofen; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Steam; Structure-Activity Relationship; Sus scrofa; Tensile Strength; Water; Wound Healing | 2014 |
3D PLLA/ibuprofen composite scaffolds obtained by a supercritical fluids assisted process.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biocompatible Materials; Drug Delivery Systems; Humans; Ibuprofen; Lactic Acid; Materials Testing; Microscopy, Electron, Scanning; Molecular Conformation; Polyesters; Polymers; Porosity; Tissue Engineering; Tissue Scaffolds | 2014 |
Nanosized mesoporous bioactive glass/poly(lactic-co-glycolic acid) composite-coated CaSiO3 scaffolds with multifunctional properties for bone tissue engineering.
Topics: 3T3 Cells; Animals; Bone Substitutes; Calcium Compounds; Coated Materials, Biocompatible; Equipment Failure Analysis; Ibuprofen; Lactic Acid; Materials Testing; Mice; Nanocapsules; Nanopores; Osteoblasts; Osteogenesis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Prosthesis Design; Silicates; Tissue Engineering; Tissue Scaffolds | 2014 |
Regulating inflammation using acid-responsive electrospun fibrous scaffolds for skin scarless healing.
Topics: Animals; Ibuprofen; Inflammation; Lactic Acid; Male; Polyesters; Polymers; Rats; Rats, Sprague-Dawley; Skin; Tissue Scaffolds; Wound Healing | 2014 |
Hierarchical porous bioactive glasses/PLGA-magnetic SBA-15 for dual-drug release.
Topics: Ceramics; Drug Delivery Systems; Drug Liberation; Durapatite; HeLa Cells; Humans; Hydrogen Bonding; Ibuprofen; Lactic Acid; Magnetics; Metformin; Microscopy, Electron, Scanning; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Silicon Dioxide | 2014 |
Mineralization and drug release of hydroxyapatite/poly(l-lactic acid) nanocomposite scaffolds prepared by Pickering emulsion templating.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Durapatite; Emulsions; Ibuprofen; Lactic Acid; Microscopy, Electron, Scanning; Minerals; Nanocomposites; Polyesters; Polymers; Tissue Scaffolds; X-Ray Diffraction | 2014 |
Facile fabrication of poly(L-lactic acid)-grafted hydroxyapatite/poly(lactic-co-glycolic acid) scaffolds by Pickering high internal phase emulsion templates.
Topics: Animals; Anti-Inflammatory Agents; Bone and Bones; Cell Proliferation; Cell Survival; Durapatite; Emulsions; Ibuprofen; Lactic Acid; Mesenchymal Stem Cells; Mice; Minerals; Molecular Weight; Nanocomposites; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tissue Engineering; Tissue Scaffolds | 2014 |
Influence of different formulations and process parameters during the preparation of drug-loaded PLGA microspheres evaluated by multivariate data analysis.
Topics: Acetates; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Excipients; Ibuprofen; Lactic Acid; Methylene Chloride; Microspheres; Multivariate Analysis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Solubility; Solvents | 2014 |
Drug release behavior of poly (lactic-glycolic acid) grafting from sodium alginate (ALG-g-PLGA) prepared by direct polycondensation.
Topics: Alginates; Anti-Inflammatory Agents, Non-Steroidal; Calcium Chloride; Colloids; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Liberation; Drug Stability; Hot Temperature; Hydrogels; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Indicators and Reagents; Lactic Acid; Microscopy, Electron, Scanning; Nanoparticles; Nanospheres; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties | 2015 |
Facile fabrication of poly(L-lactic acid) microsphere-incorporated calcium alginate/hydroxyapatite porous scaffolds based on Pickering emulsion templates.
Topics: Alginates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cell Proliferation; Cells, Cultured; Drug Liberation; Durapatite; Emulsions; Gluconates; Glucuronic Acid; Hexuronic Acids; Humans; Hydrogen-Ion Concentration; Hydrolysis; Ibuprofen; Lactic Acid; Lactones; Mesenchymal Stem Cells; Microscopy, Confocal; Microscopy, Electron, Scanning; Microspheres; Nanoparticles; Polyesters; Polymers; Porosity; Serum Albumin, Bovine; Tissue Engineering; Tissue Scaffolds | 2016 |
Prevention of adhesion bands by ibuprofen-loaded PLGA nanofibers.
Topics: Animals; Cell Adhesion; Ibuprofen; Lactic Acid; Male; Mice; Microscopy, Electron, Scanning; Models, Animal; Nanofibers; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spectroscopy, Fourier Transform Infrared | 2016 |
Massive acetaminophen overdose: effect of hemodialysis on acetaminophen and acetylcysteine kinetics.
Topics: Acetaminophen; Acetylcysteine; Acidosis, Lactic; Adolescent; Coma; Drug Overdose; Emergency Service, Hospital; Ethanol; Female; Half-Life; Humans; Ibuprofen; Lactic Acid; Liver; Renal Dialysis | 2016 |
PEGylated PLGA nanospheres optimized by design of experiments for ocular administration of dexibuprofen-in vitro, ex vivo and in vivo characterization.
Topics: Administration, Ophthalmic; Animals; Biological Availability; Cell Death; Cornea; Drug Liberation; Ibuprofen; Inflammation; Lactic Acid; Male; Nanospheres; Permeability; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Sclera | 2016 |
Electrospun PLGA Nanofiber Scaffolds Release Ibuprofen Faster and Degrade Slower After In Vivo Implantation.
Topics: Animals; Drug Implants; Ibuprofen; Lactic Acid; Nanofibers; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley | 2017 |
The binary complex of poly(PEGMA-co-MAA) hydrogel and PLGA nanoparticles as a novel oral drug delivery system for ibuprofen delivery.
Topics: 3T3 Cells; Administration, Oral; Animals; Cell Survival; Hep G2 Cells; Humans; Ibuprofen; Lactic Acid; Methacrylates; Mice; Nanoparticles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2017 |
Investigating phase separation in amorphous solid dispersions via Raman mapping.
Topics: Humidity; Ibuprofen; Lactic Acid; Microscopy; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spectrum Analysis, Raman; Temperature | 2018 |
PLGA nanoparticles are effective to control the colonic release and absorption on ibuprofen.
Topics: Animals; Colon; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Ibuprofen; Intestinal Absorption; Lactic Acid; Male; Nanoparticles; Permeability; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Wistar | 2018 |
Using PVA and TPGS as combined emulsifier in nanoprecipitation method improves characteristics and anticancer activity of ibuprofen loaded PLGA nanoparticles.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Breast Neoplasms; Caco-2 Cells; Chemistry, Pharmaceutical; Colorectal Neoplasms; Drug Liberation; Emulsifying Agents; Female; Humans; Ibuprofen; Lactic Acid; MCF-7 Cells; Mice; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Vitamin E | 2017 |
SPHRINT - Printing Drug Delivery Microspheres from Polymeric Melts.
Topics: Delayed-Action Preparations; Drug Compounding; Drug Delivery Systems; Ibuprofen; Lactic Acid; Microspheres; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Printing; Solvents | 2018 |
Transport characteristics of 5-aminosalicylic acid into colonic epithelium: Involvement of sodium-coupled monocarboxylate transporter SMCT1-mediated transport system.
Topics: Animals; Biological Transport; Ibuprofen; Intestinal Mucosa; Lactic Acid; Male; Mesalamine; Mice, Inbred ICR; Monocarboxylic Acid Transporters; Niacin; Sodium; Substrate Specificity; Tritium | 2020 |
Enhanced oral bioavailability and gastroprotective effect of ibuprofen through mixed polymer-lipid nanoparticles.
Topics: Biological Availability; Drug Carriers; Ibuprofen; Lactic Acid; Lipids; Nanoparticles; Particle Size; Polymers | 2021 |
Preclinical comparison of antinociceptive effects between ibuprofen, diclofenac, naproxen, and acetaminophen on acid-stimulated body stretching and acid-depressed feeding behaviors in rats.
Topics: Acetaminophen; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Feeding Behavior; Ibuprofen; Lactic Acid; Male; Naproxen; Pain; Rats | 2022 |