ibuprofen and l 663536

ibuprofen has been researched along with l 663536 in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (38.46)18.2507
2000's6 (46.15)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ambrosi, G; Bauer, J; Elkady, M; Laufer, SA; Luderer, S; Nieß, R; Schaible, AM; Werz, O1
Ballatore, C; Brunden, KR; Cornec, AS; James, MJ; Kovalevich, J; Lee, VM; Makani, V; Monti, L; Oukoloff, K; Smith, AB; Trojanowski, JQ; Vijayendran, KG; Yao, Y1
Baudendistel, LJ; Bradley, JD; Dahms, TE; Tanaka, H1
Garcia, I; Maier, RV; Williams, JG1
Haberman, HF; Kumar, JR; Ranadive, NS1
Ghosh, J; Myers, CE2
Ascoli, F; Bari, M; Erba, F; Finazzi-Agrò, A; Fiorucci, L; Maccarrone, M1
Bani, D; Ciuffi, M; Failli, P; Franchi-Micheli, S; Mazzetti, L; Zilletti, L1
Castonguay, A; Miller, MS; Schuller, HM; Walker, K; Weddle, DL; Zhang, L1
Daley, BJ; Enderson, BL; Gillis, RC; Karlstad, MD1
Groneberg, DA; Schmidt, R; Staats, P; Wagner, U1
Daley, BJ; Enderson, BL; Gillis, RC; Karlstad, MD; Kestler, DP1

Other Studies

13 other study(ies) available for ibuprofen and l 663536

ArticleYear
Modified acidic nonsteroidal anti-inflammatory drugs as dual inhibitors of mPGES-1 and 5-LOX.
    Journal of medicinal chemistry, 2012, Oct-25, Volume: 55, Issue:20

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Cell Line; Humans; Indomethacin; Intramolecular Oxidoreductases; Lipoxygenase Inhibitors; Microsomes; Prostaglandin-E Synthases; Pyrazoles; Structure-Activity Relationship; Sulfonamides

2012
Multitargeted Imidazoles: Potential Therapeutic Leads for Alzheimer's and Other Neurodegenerative Diseases.
    Journal of medicinal chemistry, 2017, 06-22, Volume: 60, Issue:12

    Topics: Alzheimer Disease; Animals; Arachidonate 5-Lipoxygenase; Chemistry Techniques, Synthetic; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Female; Humans; Imidazoles; Leukotrienes; Lipoxygenase Inhibitors; Male; Mice, Inbred Strains; Microtubules; Molecular Targeted Therapy; Neurodegenerative Diseases; Prostaglandins; Rats; Structure-Activity Relationship

2017
Mechanisms of increased pulmonary microvascular permeability induced by FMLP in isolated rabbit lungs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 73, Issue:5

    Topics: Animals; Capillary Permeability; Catalase; Cyclooxygenase Inhibitors; Ibuprofen; In Vitro Techniques; Indoles; Leukocyte Count; Leukotriene Antagonists; Leukotrienes; Lung; Meclofenamic Acid; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Pulmonary Circulation; Pulmonary Edema; Pulmonary Wedge Pressure; Rabbits

1992
Prostaglandin E2 mediates lipopolysaccharide-induced macrophage procoagulant activity by a cyclic adenosine monophosphate-dependent pathway.
    Surgery, 1993, Volume: 114, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Blood Coagulation Factors; Cyclic AMP; Dinoprostone; Ibuprofen; Imidazoles; Indoles; Lipopolysaccharides; Macrophages, Alveolar; Rabbits

1993
Modulation of 8-methoxypsoralen-photoinduced cutaneous inflammatory reactions by various chemotherapeutic agents in vivo.
    Photochemistry and photobiology, 1996, Volume: 63, Issue:4

    Topics: Acetophenones; Animals; Capillary Permeability; Erythema; Ibuprofen; Indoles; Indomethacin; Masoprocol; Methoxsalen; Neutrophils; PUVA Therapy; Quinacrine; Rabbits; Skin

1996
Arachidonic acid stimulates prostate cancer cell growth: critical role of 5-lipoxygenase.
    Biochemical and biophysical research communications, 1997, Jun-18, Volume: 235, Issue:2

    Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Benzoquinones; Cell Division; Cyclooxygenase Inhibitors; Eicosanoids; Enzyme Inhibitors; Flavanones; Flavonoids; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indoles; Lipoxygenase Inhibitors; Male; Masoprocol; Proadifen; Prostatic Neoplasms; Tumor Cells, Cultured

1997
Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Oct-27, Volume: 95, Issue:22

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Antineoplastic Agents; Apoptosis; Cell Membrane; Dietary Fats; Drug Combinations; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glycyrrhiza; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indoles; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mitochondria; Models, Biological; Nucleosomes; Oxidative Stress; Paeonia; Permeability; Phosphatidylserines; Prostatic Neoplasms; Tumor Cells, Cultured

1998
Human mast cells take up and hydrolyze anandamide under the control of 5-lipoxygenase and do not express cannabinoid receptors.
    FEBS letters, 2000, Feb-25, Volume: 468, Issue:2-3

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Amides; Arachidonate 5-Lipoxygenase; Arachidonic Acids; Binding, Competitive; Biological Transport; Cannabinoids; Cell Line; Cyclooxygenase Inhibitors; Endocannabinoids; Ethanolamines; Humans; Ibuprofen; Indoles; Indomethacin; Kinetics; Lipoxygenase Inhibitors; Mast Cells; Palmitic Acids; Polyunsaturated Alkamides; Receptors, Cannabinoid; Receptors, Drug; Tritium

2000
Mechanical stretch reveals different components of endothelial-mediated vascular tone in rat aortic strips.
    British journal of pharmacology, 2000, Volume: 131, Issue:7

    Topics: Acetylcholine; Aminoquinolines; Animals; Aorta, Thoracic; Cyclooxygenase Inhibitors; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Unsaturated; Guanylate Cyclase; Ibuprofen; In Vitro Techniques; Indoles; Indomethacin; Lipoxygenase Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Wistar; Stress, Mechanical; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents

2000
The cyclooxygenase inhibitor ibuprofen and the FLAP inhibitor MK886 inhibit pancreatic carcinogenesis induced in hamsters by transplacental exposure to ethanol and the tobacco carcinogen NNK.
    Journal of cancer research and clinical oncology, 2002, Volume: 128, Issue:10

    Topics: Adenocarcinoma; Animals; Arachidonic Acid; Cricetinae; Cyclooxygenase Inhibitors; DNA Primers; Ethanol; Female; Genes, p53; Genes, ras; Ibuprofen; Indoles; Lipoxygenase Inhibitors; Male; Maternal-Fetal Exchange; Mesocricetus; Nitrosamines; Pancreas; Pancreatic Neoplasms; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Pregnancy

2002
Role of downstream metabolic processing of proinflammatory fatty acids by 5-lipoxygenase in HL-60 cell apoptosis.
    The Journal of trauma, 2003, Volume: 54, Issue:1

    Topics: Apoptosis; Arachidonate 5-Lipoxygenase; Benzoquinones; Cyclooxygenase Inhibitors; DNA Fragmentation; Fatty Acids, Unsaturated; Fish Oils; Flavanones; Flavonoids; Flow Cytometry; HL-60 Cells; Humans; Ibuprofen; In Situ Nick-End Labeling; Indoles; Inflammation; Lipoxygenase Inhibitors; Necrosis; Neutrophils; Prostaglandin-Endoperoxide Synthases; Respiratory Distress Syndrome

2003
The cysteinyl-leukotriene-1 receptor antagonist zafirlukast is a potent secretagogue in rat and human airways.
    European journal of pharmacology, 2005, Dec-19, Volume: 527, Issue:1-3

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetates; Animals; Arachidonic Acid; Bronchi; Chromones; Cyclooxygenase Inhibitors; Cyclopropanes; Dose-Response Relationship, Drug; Humans; Ibuprofen; Indoles; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Membrane Proteins; Morpholines; Phenylcarbamates; Phosphoinositide-3 Kinase Inhibitors; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Leukotriene; Sulfides; Sulfonamides; Tosyl Compounds; Trachea

2005
Regulation of apoptosis in eicosapentaenoic acid-treated HL-60 cells.
    The Journal of surgical research, 2007, Volume: 137, Issue:1

    Topics: Apoptosis; Arachidonate 12-Lipoxygenase; Arachidonate 15-Lipoxygenase; Arachidonate 5-Lipoxygenase; Cyclooxygenase Inhibitors; Eicosapentaenoic Acid; Enzyme Inhibitors; Fatty Acids, Unsaturated; Flavanones; Guaiacol; HL-60 Cells; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indoles; Leukotriene B4; Lignans; Lipoxygenase Inhibitors; Neutrophils; Respiratory Distress Syndrome

2007