ibuprofen has been researched along with ketorolac in 76 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.32) | 18.7374 |
| 1990's | 14 (18.42) | 18.2507 |
| 2000's | 19 (25.00) | 29.6817 |
| 2010's | 31 (40.79) | 24.3611 |
| 2020's | 11 (14.47) | 2.80 |
| Authors | Studies |
|---|---|
| Bell, MR; D'Ambra, TE; Daum, SJ; Eissenstat, MA; Herrmann, JL; Hlasta, DJ; Kumar, V; Philion, RE; Rosi, D; Wetzel, JR | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chuang, S; Horne, J; Porter, CJ; Scanlon, MJ; Velkov, T | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Cabrita, EJ; Corvo, MC; Manso, J; Marques, MM; Viegas, A | 1 |
| Kumar, M; Sinha, VR; Thareja, S | 1 |
| Buckley, DB; Funk, RS; Hensley, T; Kazmi, F; Loewen, GJ; Parkinson, A; Pope, C | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Headey, SJ; Hughes, ML; Laguerre, A; Mohanty, B; Patil, R; Porter, CJ; Scanlon, MJ; Wielens, J; Williams, ML | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, TA; Nakagawa, A; Smith, CE; Soti, S; Xue, D; Yin, H | 1 |
| Gasparich, JP; Mayo, ME | 1 |
| Paris, PM; Seaberg, DC; Turturro, MA | 1 |
| Blumenthal, PD; Furman, WR; Givogre, JL; Higgins, MS; Marco, AP | 1 |
| Morrison, NA; Repka, MX | 1 |
| Price, SD; Watson, WA; Wright, JM | 1 |
| Balevi, B | 1 |
| Rømsing, J; Walther-Larsen, S | 1 |
| Frölich, JC; Stichtenoth, DO | 1 |
| Todd, KH | 1 |
| Michael, LR; Southall, DM; Vasko, RM | 1 |
| Hall, SR; Loomis, C; Milne, B | 1 |
| Fowler, CJ; Janson, U; Johnson, RM; Norström, K; Stenström, A; Tiger, G; Wahlström, G | 1 |
| Browne, GS; Day, RO; Ellis, BA; Nelson, C; Nguyen, T; Williams, KM | 1 |
| Bell, A; Hosokawa, A; Jhamandas, K; Milne, B; Powell, KJ; Quirion, R; Sutak, M | 1 |
| Junger, H; Sorkin, LS | 1 |
| Bozzo, J; Escolar, G; Galán, AM; Hernández, MR; Ordinas, A | 1 |
| Browning, RA; Burgess, FW | 1 |
| Coleman, CN; Palayoor, ST; Tofilon, PJ | 1 |
| Ahmad, F; Cheruku, KK; Ghani, A; Pappas, P; Silver, MA; Silverman, PR; Zelinger, A | 1 |
| Permi, J; Rosenberg, PH; Toivonen, J | 1 |
| Coté, CJ; Dsida, R | 1 |
| Wartell, RL | 1 |
| Berger, MY; Bruijn, JK; Damen, L; Koes, BW; Passchier, J; Verhagen, AP | 1 |
| Arora, S; Herbert, M; Wagner, JG | 1 |
| Aranda, JV; Beharry, KD; Valencia, GB | 1 |
| Burke, A; Cansino, C; Edelman, A; Jamshidi, R | 1 |
| Aggarwal, V; Kabi, D; Singla, M | 1 |
| Van Hulle Vincent, C; Wang, E; Wilkie, DJ | 2 |
| Voepel-Lewis, T | 1 |
| Unlü, B; van Leeuwen, JS; Vermeulen, NP; Vos, JC | 1 |
| Craig, KD; Schiavenato, M; von Baeyer, CL | 1 |
| Braaten, KP; Fortin, J; Goldberg, AB; Hurwitz, S | 1 |
| Hsu, JR; Noel, SP; Rathbone, CR; Rivera, JC; Wenke, JC | 1 |
| Dimas, V; Ditthakasem, K; Fearon, JA; Herbert, MA | 1 |
| Aravamuthan, BR; Mar, SS; Williams, KG | 1 |
| Bosoy, D; Cohen, V; Fromm, C; Hossain, R; Jellinek-Cohen, SP; Likourezos, A; Marshall, J; Motov, S; Rockoff, B; Smith, A | 1 |
| Dayno, J; Niebler, G | 1 |
| Aranda, JV; Beharry, KD; Cai, CL; Lazzaro, D; Salomone, F; Valencia, AM; Valencia, GB | 1 |
| Krawczeski, CD; Kwiatkowski, DM; Montez-Rath, ME; Sutherland, SM; Uber, AM | 1 |
| Isenberg, DL; Wasserman, DD | 1 |
| Baratta, JL; Dayan, AC; Pitchon, DN; Schwenk, ES; Viscusi, ER | 1 |
| Balzer, S; Beck, M; Drum, M; Fowler, S; Nusstein, J; Reader, A; Watts, K | 1 |
| Gutmann, JL; Jinatongthai, P; Nagendrababu, V; Pulikkotil, SJ; Teerawattanapong, N; Veettil, SK | 1 |
| Dwarica, DS; Nihira, MA; Pickett, SD; Quiroz, LH; Zhao, YD | 1 |
| Aranda, N; Miranda, HF; Noriega, V; Poblete, P; Prieto, JC; Sierralta, F | 1 |
| Allen, IE; Auerbach, A; Bongiovanni, T; Lancaster, E; Ledesma, Y; Steinman, MA; Whitaker, E; Wick, E | 1 |
| Cortijo-Brown, A; Davitt, M; Feliciano, C; Friedman, BW; Irizarry, E; Restivo, A; Salama, M | 1 |
| Kelley-Quon, LI; Kim, E; Kingston, P; Lascano, D; Ourshalimian, S; Russell, CJ | 1 |
| Akira, R; Bassi, APF; Chiba, F; de Lima Neto, TJ; Faverani, LP; Grossi-Oliveira, GA; Han, M; Miloro, M; Momesso, GAC; Polo, TOB; Rios, BR; Silva, WPP; Sumida, DH | 1 |
| Slawson, DC | 1 |
| Gorenflo, M; Saur, P; van den Anker, JN; van Dyk, M; Welzel, T; Ziesenitz, VC | 1 |
| Chiu, SH; Indermuhle, P; Mori, C; Zelko, M | 1 |
| Abdelbaser, I; ALseoudy, MM; El-Emam, EM; Mageed, NA | 1 |
| Elnaghy, AM; Elsaka, SE; Elshazli, AH | 1 |
| Amaddeo, A; Barbi, E; Barbieri, F; Cozzi, G; De Nardi, L; Ghirardo, S; Maestro, A; Ronfani, L; Trevisan, M; Zanon, D | 1 |
9 review(s) available for ibuprofen and ketorolac
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Peri-operative use of nonsteroidal anti-inflammatory drugs in children: analgesic efficacy and bleeding.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Diclofenac; Drug Administration Schedule; Humans; Ibuprofen; Infant; Ketorolac; Pain, Postoperative; Postoperative Hemorrhage; Randomized Controlled Trials as Topic; Tolmetin | 1997 |
Symptomatic treatment of migraine in children: a systematic review of medication trials.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Child, Preschool; Controlled Clinical Trials as Topic; Dihydroergotamine; Female; Humans; Ibuprofen; Ketorolac; Male; Migraine Disorders; Prochlorperazine; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Sulfonamides; Sumatriptan | 2005 |
Myth: parenteral ketorolac provides more effective analgesia than oral ibuprofen.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Emergency Service, Hospital; Humans; Ibuprofen; Infusions, Parenteral; Ketorolac; Pain | 2007 |
Nonsteroidal anti-inflammatory drugs (NSAIDs) in the newborn - which ones?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Hemorrhage; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Ketorolac | 2009 |
Updates on Multimodal Analgesia for Orthopedic Surgery.
Topics: Acetaminophen; Amines; Analgesia; Celecoxib; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Ibuprofen; Ketamine; Ketorolac; Orthopedic Procedures; Pain, Postoperative | 2018 |
Efficacy and Safety of Oral Premedication on Pain after Nonsurgical Root Canal Treatment: A Systematic Review and Network Meta-analysis of Randomized Controlled Trials.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Databases, Bibliographic; Female; Humans; Ibuprofen; Ketorolac; Male; Middle Aged; Pain, Postoperative; Piroxicam; Prednisolone; Premedication; Randomized Controlled Trials as Topic; Root Canal Therapy; Sulindac; Treatment Outcome; Young Adult | 2019 |
Systematic Review and Meta-Analysis of the Association Between Non-Steroidal Anti-Inflammatory Drugs and Operative Bleeding in the Perioperative Period.
Topics: Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Blood Loss, Surgical; Blood Transfusion; Diclofenac; Humans; Ibuprofen; Ketorolac; Pain, Postoperative; Pain, Procedural; Perioperative Period; Postoperative Hemorrhage; Surgical Procedures, Operative; Treatment Outcome | 2021 |
Efficacy and Safety of NSAIDs in Infants: A Comprehensive Review of the Literature of the Past 20 Years.
Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Child; Chronic Disease; Diclofenac; Flurbiprofen; Humans; Ibuprofen; Infant; Ketoprofen; Ketorolac; Meloxicam; Naproxen; Niflumic Acid; Pain | 2022 |
16 trial(s) available for ibuprofen and ketorolac
| Article | Year |
|---|---|
Intramuscular ketorolac versus oral ibuprofen in acute musculoskeletal pain.
Topics: Administration, Oral; Adolescent; Adult; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Humans; Ibuprofen; Injections, Intravenous; Ionophores; Ketorolac; Middle Aged; Musculoskeletal Diseases; Pain; Prospective Studies; Tolmetin; Wounds and Injuries | 1995 |
Recovery from outpatient laparoscopic tubal ligation is not improved by preoperative administration of ketorolac or ibuprofen.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Ketorolac; Laparoscopy; Pain, Postoperative; Premedication; Prospective Studies; Sterilization, Tubal; Time Factors; Tolmetin; Treatment Outcome | 1994 |
Ketorolac versus acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Ibuprofen; Injections, Intravenous; Ketorolac; Male; Middle Aged; Pain, Postoperative; Prospective Studies; Strabismus; Tolmetin | 1994 |
Efficacy of nonsteroidal anti-inflammatory medications for prevention of atrial fibrillation following coronary artery bypass graft surgery.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Atrial Fibrillation; Coronary Artery Bypass; Female; Humans; Ibuprofen; Ketorolac; Male; Middle Aged; Postoperative Complications; Risk Factors | 2004 |
Analgesia and discharge following preincisional ilioinguinal and iliohypogastric nerve block combined with general or spinal anaesthesia for inguinal herniorrhaphy.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Analgesia; Analgesics, Opioid; Anesthesia, General; Anesthesia, Spinal; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Codeine; Female; Fentanyl; Hernia, Inguinal; Humans; Ibuprofen; Ketorolac; Length of Stay; Male; Middle Aged; Nerve Block; Pain Measurement; Pain, Postoperative; Treatment Outcome | 2004 |
Paracervical block with combined ketorolac and lidocaine in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Adult; Anesthesia, Obstetrical; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Ketorolac; Lidocaine; Pain; Pregnancy; Young Adult | 2009 |
Comparative evaluation of effect of preoperative oral medication of ibuprofen and ketorolac on anesthetic efficacy of inferior alveolar nerve block with lidocaine in patients with irreversible pulpitis: a prospective, double-blind, randomized clinical tri
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Ketorolac; Lidocaine; Male; Mandibular Nerve; Nerve Block; Preanesthetic Medication; Premedication; Prospective Studies; Pulpitis; Root Canal Therapy; Statistics, Nonparametric; Young Adult | 2010 |
Intramuscular ketorolac versus oral ibuprofen for pain relief in first-trimester surgical abortion: a randomized clinical trial.
Topics: Abortion, Induced; Administration, Oral; Adolescent; Adult; Analgesia; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Ibuprofen; Injections, Intramuscular; Ketorolac; Young Adult | 2014 |
A Randomized Controlled Trial of Oral Versus Intravenous Administration of a Nonnarcotic Analgesia Protocol Following Pediatric Craniosynostosis Corrections on Nausea and Vomiting Rates.
Topics: Acetaminophen; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Child; Child, Preschool; Craniosynostoses; Female; Humans; Ibuprofen; Infant; Infusions, Intravenous; Ketorolac; Length of Stay; Male; Operative Time; Postoperative Nausea and Vomiting; Prospective Studies; Single-Blind Method | 2015 |
Ibuprofen and Acetaminophen Versus Intranasal Ketorolac (Sprix) in an Untreated Endodontic Pain Model: A Randomized, Double-blind Investigation.
Topics: Acetaminophen; Acute Pain; Administration, Intranasal; Administration, Oral; Adult; Dental Pulp Necrosis; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Ketorolac; Male; Periapical Periodontitis; Pulpitis; Severity of Illness Index; Treatment Outcome; Young Adult | 2019 |
Comparing Ketorolac With Ibuprofen for Postoperative Pain: A Randomized Clinical Trial.
Topics: Administration, Intravenous; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Ketorolac; Middle Aged; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Prospective Studies | 2020 |
A randomized controlled trial of ibuprofen versus ketorolac versus diclofenac for acute, nonradicular low back pain.
Topics: Acute Pain; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Humans; Ibuprofen; Ketorolac; Low Back Pain | 2021 |
A triple-blind randomized clinical trial of different associations between dexamethasone and non-steroids anti-inflammatories for preemptive action in third molar extractions.
Topics: Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Drug Therapy, Combination; Etodolac; Female; Glucocorticoids; Humans; Ibuprofen; Ketorolac; Male; Molar, Third; Phenylpropionates; Prospective Studies; Tooth Extraction; Young Adult | 2021 |
Comparison of intravenous ibuprofen versus ketorolac for postoperative analgesia in children undergoing lower abdominal surgery: A randomized, controlled, non-inferiority study.
Topics: Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Child; Double-Blind Method; Humans; Ibuprofen; Ketorolac; Morphine; Pain, Postoperative; Tolmetin | 2022 |
Effectiveness of oral premedication of meloxicam, ketorolac, dexamethasone, and ibuprofen on the success rate of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a prospective, double-blind, randomized controlled trial.
Topics: Anesthesia, Dental; Anesthetics, Local; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Ketorolac; Lidocaine; Mandibular Nerve; Meloxicam; Nerve Block; Pain; Premedication; Prospective Studies; Pulpitis | 2023 |
Oral ibuprofen versus oral ketorolac for children with moderate and severe acute traumatic pain: a randomized comparative study.
Topics: Acute Pain; Administration, Oral; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Child; Double-Blind Method; Humans; Ibuprofen; Ketorolac | 2023 |
51 other study(ies) available for ibuprofen and ketorolac
| Article | Year |
|---|---|
Antinociceptive (aminoalkyl)indoles.
Topics: Analgesia; Analgesics; Animals; Chemical Phenomena; Chemistry; Cyclooxygenase Inhibitors; Indoles; Magnetic Resonance Spectroscopy; Male; Methylation; Mice; Molecular Conformation; Molecular Structure; Muscle Contraction; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Vas Deferens | 1991 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Characterization of the drug binding specificity of rat liver fatty acid binding protein.
Topics: Anilino Naphthalenesulfonates; Animals; Fatty Acid-Binding Proteins; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Fluorescence; Substrate Specificity | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Binding of ibuprofen, ketorolac, and diclofenac to COX-1 and COX-2 studied by saturation transfer difference NMR.
Topics: Animals; Binding, Competitive; Catalytic Domain; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Female; Ibuprofen; Ketorolac; Magnetic Resonance Spectroscopy; Male; Sheep | 2011 |
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship | 2012 |
Lysosomal sequestration (trapping) of lipophilic amine (cationic amphiphilic) drugs in immortalized human hepatocytes (Fa2N-4 cells).
Topics: Adrenergic beta-Antagonists; Amines; Ammonium Chloride; Antidepressive Agents, Tricyclic; Atorvastatin; Cell Line, Transformed; Diuretics; Hepatocytes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imipramine; Lysosomes; Monensin; Nigericin; Propranolol; Pyrroles | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Characterization of two distinct modes of drug binding to human intestinal fatty acid binding protein.
Topics: Fatty Acid-Binding Proteins; Fluorescent Dyes; Humans; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Spectrometry, Fluorescence | 2014 |
Non-steroidal Anti-inflammatory Drugs Are Caspase Inhibitors.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Caspase Inhibitors; Caspases; Caspases, Initiator; Cell Line; Cell Survival; High-Throughput Screening Assays; Humans; Ibuprofen; Inhibitory Concentration 50; Ketorolac; Naproxen; Small Molecule Libraries; Substrate Specificity | 2017 |
Comparative effects of four prostaglandin synthesis inhibitors on the obstructed kidney in the dog.
Topics: Animals; Blood Pressure; Dogs; Female; Ibuprofen; Indomethacin; Ketorolac; Kidney Pelvis; Naproxen; Pressure; Prostaglandin Antagonists; Tolmetin; Ureteral Obstruction | 1986 |
NSAID use and efficacy in the emergency department: single doses of oral ibuprofen versus intramuscular ketorolac.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Emergency Service, Hospital; Female; Hospitals, Teaching; Hospitals, Urban; Humans; Ibuprofen; Injections, Intramuscular; Ketorolac; Male; Pain; Pain Measurement; Retrospective Studies; Tolmetin | 1994 |
Ketorolac versus ibuprofen: a simple cost-efficacy comparison for dental use.
Topics: Analgesics; Cost-Benefit Analysis; Humans; Ibuprofen; Ketorolac; Pain, Postoperative; Tolmetin; Tooth Extraction; Toothache | 1994 |
Anesthesiology.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Ketorolac; Pain, Postoperative; Piroxicam; Tolmetin | 1998 |
If you have no destination, any road will do.
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Ketorolac; Musculoskeletal System; Pain; Research Design; Tolmetin | 1998 |
Intrathecal NSAIDS attenuate inflammation-induced neuropeptide release from rat spinal cord slices.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Cyclooxygenase Inhibitors; Freund's Adjuvant; Hyperalgesia; Ibuprofen; In Vitro Techniques; Injections, Spinal; Ketorolac; Male; Myelitis; Neuropeptides; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tolmetin | 1998 |
Spinal action of ketorolac, S(+)- and R(-)-ibuprofen on non-noxious activation of the catechol oxidation in the rat locus coeruleus: evidence for a central role of prostaglandins in the strychnine model of allodynia.
Topics: Anesthesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Catechols; Electrophysiology; Glycine Agents; Ibuprofen; Injections, Spinal; Ketorolac; Locus Coeruleus; Oxidation-Reduction; Pain; Physical Stimulation; Rats; Spinal Cord; Strychnine; Tolmetin | 1999 |
Inhibition of anandamide hydrolysis by the enantiomers of ibuprofen, ketorolac, and flurbiprofen.
Topics: Aging; Animals; Arachidonic Acids; Brain; Cell Extracts; Cell Survival; Dose-Response Relationship, Drug; Endocannabinoids; Flurbiprofen; Glioma; Hydrolysis; Ibuprofen; Inhibitory Concentration 50; Ketorolac; Kinetics; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Stereoisomerism; Time Factors; Tolmetin; Tumor Cells, Cultured | 1999 |
Stereoselective and substrate-dependent inhibition of hepatic mitochondria beta-oxidation and oxidative phosphorylation by the non-steroidal anti-inflammatory drugs ibuprofen, flurbiprofen, and ketorolac.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Coenzyme A; Flurbiprofen; Ibuprofen; Ketorolac; Lipid Metabolism; Male; Mitochondria, Liver; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Palmitic Acid; Rats; Rats, Wistar; Stereoisomerism; Tolmetin | 1999 |
Comparative effects of cyclo-oxygenase and nitric oxide synthase inhibition on the development and reversal of spinal opioid tolerance.
Topics: Analgesics, Opioid; Animals; Cyclooxygenase Inhibitors; Drug Tolerance; Enzyme Inhibitors; Ibuprofen; Injections, Intraperitoneal; Injections, Spinal; Ketorolac; Male; Morphine; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nociceptors; Rats; Rats, Sprague-Dawley; Spinal Cord; Tolmetin | 1999 |
Isoprostanes induce plasma extravasation in rat skin.
Topics: Animals; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; F2-Isoprostanes; Ibuprofen; Inflammation; Injections, Subcutaneous; Isoprostanes; Ketorolac; Male; Rats | 2000 |
Prohemorrhagic potential of dipyrone, ibuprofen, ketorolac, and aspirin: mechanisms associated with blood flow and erythrocyte deformability.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Abdominal; Aspirin; Dipyrone; Endothelium, Vascular; Erythrocyte Deformability; Hemorrhagic Disorders; Humans; Ibuprofen; Ketorolac; Platelet Aggregation; Rabbits; Regional Blood Flow | 2001 |
Nonsteroidal anti-inflammatory drugs for perioperative pain control.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Etodolac; Humans; Ibuprofen; Indomethacin; Ketorolac; Lactones; Nabumetone; Naproxen; Pain, Postoperative; Piroxicam; Pyrazoles; Sulfonamides; Sulfones; Time Factors | 2001 |
Ibuprofen-mediated reduction of hypoxia-inducible factors HIF-1alpha and HIF-2alpha in prostate cancer cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Basic Helix-Loop-Helix Transcription Factors; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation, Neoplastic; Glucose Transporter Type 1; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Ibuprofen; Isoenzymes; Ketorolac; Male; Membrane Proteins; Monosaccharide Transport Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostatic Neoplasms; Sulfonamides; Time Factors; Trans-Activators; Transcription Factors; Up-Regulation; Vascular Endothelial Growth Factor A | 2003 |
Nonsteroidal antiinflammatory drugs and hemorrhage following tonsillectomy: do we have the data?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Ketorolac; Postoperative Hemorrhage; Tonsillectomy | 2004 |
Parecoxib versus ibuprofen.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Humans; Ibuprofen; Injections, Intramuscular; Isoxazoles; Ketorolac; Pain, Postoperative; Tooth Extraction | 2005 |
Pediatric nurses' beliefs and pain management practices: an intervention pilot.
Topics: Analgesics; Feasibility Studies; Humans; Ibuprofen; Ketorolac; Nurses; Pain; Pediatric Nursing; Pilot Projects; Surveys and Questionnaires; Workforce | 2011 |
Bridging the gap between pain assessment and treatment: time for a new theoretical approach?
Topics: Analgesics; Humans; Ibuprofen; Ketorolac; Nurses; Pain; Pediatric Nursing; Workforce | 2011 |
Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; ATP-Binding Cassette Transporters; Biological Transport, Active; Cytochrome P-450 Enzyme System; Diclofenac; Electron Transport; Genes, MDR; Ibuprofen; Indomethacin; Ketoprofen; Ketorolac; Mitochondria; Naproxen; Reactive Oxygen Species; Sulindac; Tolmetin; Yeasts | 2012 |
Self-report is a primary source of information about pain, but it is not infallible: a comment on "response to Voepel-Lewis's letter to the editor, 'bridging the gap between pain assessment and treatment: time for a new theoretical approach?'".
Topics: Analgesics; Humans; Ibuprofen; Ketorolac; Nurses; Pain; Pediatric Nursing; Workforce | 2013 |
Response to Schiavenato, von Baeyer, and Craig's letter to the editor.
Topics: Analgesics; Humans; Ibuprofen; Ketorolac; Nurses; Pain; Pediatric Nursing; Workforce | 2013 |
Locally Delivered Nonsteroidal Antiinflammatory Drug: A Potential Option for Heterotopic Ossification Prevention.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Proliferation; Cell Survival; Cells, Cultured; Disease Models, Animal; DNA Replication; Female; Humans; Ibuprofen; Indomethacin; Ketorolac; Male; Ossification, Heterotopic; Osteoblasts; Rats; Skin; Time Factors; Wound Healing; Wounds and Injuries | 2015 |
Factors Associated With Discharge After Initial Emergency Treatment of Pediatric Migraine.
Topics: Administration, Intranasal; Administration, Intravenous; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Child; Emergency Service, Hospital; Emergency Treatment; Female; Humans; Ibuprofen; Ketorolac; Male; Migraine Disorders; Pain; Pain Measurement; Patient Discharge; Retrospective Studies; Treatment Outcome | 2017 |
Development of an opioid reduction protocol in an emergency department.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Chronic Pain; Emergency Service, Hospital; Humans; Ibuprofen; Ketorolac; Pain Measurement; Patient Satisfaction; Severity of Illness Index; Time Factors | 2015 |
Effect size comparison of ketorolac nasal spray and commonly prescribed oral combination opioids for pain relief after third molar extraction surgery.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Female; Humans; Hydrocodone; Ibuprofen; Ketorolac; Male; Molar, Third; Nasal Sprays; Oxycodone; Pain Measurement; Pain, Postoperative; Randomized Controlled Trials as Topic; Tooth Extraction; Tramadol; Treatment Outcome; Young Adult | 2016 |
Human retinal endothelial cells and astrocytes cultured on 3-D scaffolds for ocular drug discovery and development.
Topics: Astrocytes; Biomimetics; Coculture Techniques; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Dinoprost; Dinoprostone; Drug Discovery; Drug Interactions; Endothelial Cells; Humans; Ibuprofen; Ketorolac; Retina; Thromboxane B2 | 2018 |
Nephrotoxin exposure and acute kidney injury in critically ill children undergoing congenital cardiac surgery.
Topics: Acute Kidney Injury; Adolescent; Aspirin; Cardiac Surgical Procedures; Child; Child, Preschool; Critical Illness; Enalapril; Female; Heart Defects, Congenital; Humans; Ibuprofen; Infant; Ketorolac; Male; Piperacillin, Tazobactam Drug Combination; Postoperative Complications; Retrospective Studies; Vancomycin | 2018 |
A Case of Acute Traumatic Lumbar Paraspinal Compartment Syndrome.
Topics: Accidental Falls; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Compartment Syndromes; Female; Humans; Ibuprofen; Ketorolac; Lumbosacral Region; Morphine; Obesity, Morbid; Paraspinal Muscles; Tomography, X-Ray Computed | 2018 |
Nitric Oxide and Opioids Involvement in Isobolographic Nsaids Antinociception.
Topics: Acetaminophen; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Ibuprofen; Ketoprofen; Ketorolac; Mice; Nitric Oxide; Pain; Pain Measurement | 2019 |
Ketorolac use and risk of bleeding after appendectomy in children with perforated appendicitis.
Topics: Appendectomy; Appendicitis; Child; Hemorrhage; Humans; Ibuprofen; Ketorolac; Retrospective Studies | 2022 |
Ibuprofen, Ketorolac, and Diclofenac Are Equivalent for the Treatment of Acute, Nonradicular Low Back Pain.
Topics: Acute Pain; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Humans; Ibuprofen; Ketorolac; Low Back Pain | 2022 |
Use of Scheduled Nonopioid Analgesia to Decrease Inpatient Opioid Consumption After Scheduled Cesarean Birth.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Female; Humans; Ibuprofen; Inpatients; Ketorolac; Oxycodone; Pain, Postoperative; Pregnancy | 2022 |