ibuprofen has been researched along with ketoprofen in 316 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (12.03) | 18.7374 |
| 1990's | 42 (13.29) | 18.2507 |
| 2000's | 93 (29.43) | 29.6817 |
| 2010's | 116 (36.71) | 24.3611 |
| 2020's | 27 (8.54) | 2.80 |
| Authors | Studies |
|---|---|
| Behn, DC; Botton, I; Fellows, CA; Laskowski, SC; Phillips, DK; Schlegel, DC; Speight, PT; Zenitz, BL | 1 |
| Inui, KI; Masuda, S; Saito, H | 1 |
| Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Cihlar, T; Ho, ES; Mulato, AS | 1 |
| Inui, K; Saito, H; Uwai, Y | 1 |
| Faller, B; Wohnsland, F | 1 |
| Abe, T; Itoh, T; Kato, Y; Kusuhara, H; Meier, PJ; Shitara, Y; Sugiyama, D; Sugiyama, Y | 1 |
| Cha, SH; Endou, H; Hosoyamada, M; Khamdang, S; Kimura, H; Narikawa, S; Sekine, T; Takeda, M | 1 |
| Borst, P; de Haas, M; Kuil, A; Reid, G; van der Heijden, I; Wielinga, P; Wijnholds, J; Zelcer, N | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Charitos, C; Doulgkeris, C; Galanakis, D; Gavalas, A; Kourounakis, AP; Kourounakis, PN; Kravaritou, C; Rekka, EA; Tsiakitzis, KC | 1 |
| Beroza, P; Cai, D; Damodaran, K; Gomez, RF; Hsu, N; Keck, JG; Laborde, E; Lum, RT; Macke, TJ; Martin, G; Schow, SR; Simon, RJ; Villar, HO; Wick, MM | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A | 1 |
| Caron, G; Ermondi, G | 1 |
| Brozic, P; Gobec, S; Rizner, TL | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Fei, YJ; Ganapathy, V; Gopal, E; Itagaki, S; Miyauchi, S; Prasad, PD; Zhuang, L | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Anderluh, M; Brunskole, M; Gobec, S; Lanisnik Rizner, T; Stefane, B; Stojan, J; Zorko, K | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Avdeef, A; Tam, KY | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P | 1 |
| Akamatsu, M | 1 |
| Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
| Horie, T; Horiguchi, A; Kitamura, S; Kotake, Y; Ohshita, H; Ohta, S; Sanoh, S; Sugihara, K; Tateno, C; Tayama, Y | 1 |
| Kumar, M; Sinha, VR; Thareja, S | 1 |
| Ambrosi, G; Bauer, J; Elkady, M; Laufer, SA; Luderer, S; Nieß, R; Schaible, AM; Werz, O | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Buckley, DB; Funk, RS; Hensley, T; Kazmi, F; Loewen, GJ; Parkinson, A; Pope, C | 1 |
| Capim, SL; Dos Santos, GC; Gonçalves, GM; Marinho, BG; Vasconcellos, ML | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Headey, SJ; Hughes, ML; Laguerre, A; Mohanty, B; Patil, R; Porter, CJ; Scanlon, MJ; Wielens, J; Williams, ML | 1 |
| Dalby, KN; Kaoud, TS; Radwan, MF | 1 |
| Brewster, C; Deering-Rice, CE; Reilly, CA; Rose, TM | 1 |
| Alcaraz, B; Bratoeff, E; Cabeza, M; Camacho-Arroyo, I; Garrido, M; González-Arenas, A | 1 |
| Chen, T; Guan, J; Liao, J; Luo, J; Qin, X; Talley, JJ; Tortorella, MD; Tu, Z; Zhang, Y | 1 |
| Kourounakis, PN; Kourti, M; Rekka, EA; Theodosis-Nobelos, P; Tziona, P | 1 |
| Gavalas, A; Kourti, M; Rekka, EA; Theodosis-Nobelos, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Jones, TA; Nakagawa, A; Smith, CE; Soti, S; Xue, D; Yin, H | 1 |
| Boixareu, N; Campanera, JM; Navarro, L; Pors, K; Pouplana, R; Pujol, MD; Rosell, G; Sánchez, S | 1 |
| Bartolucci, G; Bua, S; Carta, F; Di Cesare Mannelli, L; Ghelardini, C; Gratteri, P; Lucarini, L; Masini, E; Menicatti, M; Micheli, L; Nocentini, A; Selleri, S; Supuran, CT | 1 |
| Altman, RA; Borel, T; Davis, I; de Azambuja, F; Johnson, D; Liu, A; Sorrentino, JP; Udokwu, C; Yang, Y | 1 |
| Anderson, JA; Buchanan, WW; Lee, P; Miller, J; Webb, J | 1 |
| Mann, NS; Sachdev, AJ | 1 |
| Huskisson, EC | 1 |
| Akimoto, T; Saito, T; Tachizawa, H; Tsukada, W | 1 |
| Hart, FD | 1 |
| Miehlke, K | 1 |
| Marini, U; Spotti, D; Visconti, G | 1 |
| Bennett, RM; Calin, A; Giuliano, VJ; Goldman, AL; Montoya, HE; O'Brien, WM; Sakofsky, HY; Schmid, FR; Sukhupunyaraksa, S; Willkens, RF | 1 |
| Giaccai, L; Melani, F; Pengue, L | 1 |
| Saxena, RP; Saxena, U | 1 |
| Burdeĭnyĭ, AP | 1 |
| Pemberton, RE; Strand, LJ | 1 |
| Fumagalli, M; Liverta, C; Montrone, F; Pellegrini, P; Pollini, C; Pontiroli, AE; Ratti, G; Sala, G | 1 |
| Spisani, S; Traniello, S; Vanzini, G | 1 |
| Baron, SH; Bevilacqua, M; Foà, PP; Lengel, F; Micossi, P; Norbiato, G; Pontiroli, AE; Raggi, U; Tamayo, RC | 1 |
| Nagai, T; Nambu, N; Shimoda, M; Takahashi, Y; Ueda, H | 1 |
| Irwin, WJ; Slack, JA | 1 |
| Balme, HW; Franklin, S; Huskisson, EC; Scott, J; Woolf, DL | 1 |
| Grahame, R | 1 |
| Kitchen, EA; Meacock, SC | 1 |
| Guyonnet, JC; Julou, L | 1 |
| Brune, K; Geisslinger, G; Menzel-Soglowek, S | 3 |
| Davies, NW; Francis, HW; Jack, DS; Rumble, RH | 1 |
| Drsata, J; Gregorová, J; Pribová, M | 1 |
| Jones, ME; Knights, KM | 1 |
| Brune, K; Geisslinger, G; Menzel-Soglowek, S; Mollenhauer, J | 1 |
| Aligia, C; Kelloff, G; Kulkarni, N; Reddy, BS; Tokumo, K | 1 |
| Abiteboul, M; Bergmann, JF; Caulin, C; Chassany, O; Genève, J; Segrestaa, JM | 1 |
| Hersh, EV | 1 |
| Ambrus, JL; Chesky, L; Engler, RJ; Haneiwich, S; McFarland, P | 1 |
| Neuvonen, PJ | 1 |
| Casady, RL; Itoh, T; Magavi, R; Nishihata, T; Rytting, JH | 1 |
| Fritz, ME; Green, MD; Mayambala, CS; Odle, BM; Offenbacher, S; Sena, FJ; Smith, MA; van Dyke, TE; Yeh, KC | 1 |
| Kawakubo, H; Matsumoto, K; Nishikawa, K; Suehiro, S; Toyomaki, Y; Yago, H | 1 |
| Blessington, B; Crabb, N; Karkee, S; Northage, A | 1 |
| Paulus, HE; Schlegel, SI | 1 |
| Mehlisch, DR | 1 |
| Atkinson, LK; Goodship, TH; Ward, MK | 1 |
| Sallmann, AR | 2 |
| Jelić-Ivanović, Z; Majkić-Singh, N; Spasić, S; Todorović, P | 1 |
| Machtey, I | 1 |
| Ward, JR | 1 |
| Court, H; Volans, GN | 1 |
| Isomäki, H; Kaarela, K; Kajander, A; Koota, K; Lehtinen, K; Luukkainen, R; Martio, J; Martio, T; Nissilä, M; Nuotio, P | 1 |
| Bailey, RR; Lynn, KL; Munn, E | 1 |
| Keinänen-Kiukaanniemi, S; Kouvalainen, K; Similä, S | 1 |
| Bramanti, G; La Porta, E; Mazzi, G; Mura, P; Papini, P; Pinzauti, S | 1 |
| Bajardi, M; Giammona, G; Palazzo, S; Pitarresi, G; Roccaro, A | 1 |
| Lange, R; Lentz, R | 1 |
| Cymerman, JJ; Frankson, M; Lemon, RR; Maggio, JD; Schilder, H; Torabinejad, M | 1 |
| Dorn, SO; Eleazer, PD; Frankson, M; Jouhari, B; Mullin, RK; Soluti, A; Torabinejad, M | 1 |
| Cederlund, H; Mårdh, PA | 1 |
| Baeyens, W; Donato, MG; Sandra, P; van den Bossche, W | 1 |
| Beck, WS; Brune, K; Geisslinger, G; Menzel, S | 1 |
| English, N; Hughes, V; Wolf, CR | 1 |
| Kantoci, D; Wechter, WJ | 1 |
| Becker, L; Eberlein-König, B; Przybilla, B | 1 |
| Cohen, AF; Hoedemaker, HG; Jacobs, LD; Ouwersloot-van der Meij, MJ; Reints, A; Schoemaker, RC; van Gerven, JM | 1 |
| Davies, NM; Jamali, F; Russell, AS; Wright, MR | 1 |
| Balint, G; Krause, W; Link, R; Otto, J; Pavlik, G | 1 |
| Frölich, JC; Gutzki, FM; Stichtenoth, DO; Tsikas, D | 1 |
| Fox, SM; Johnston, SA | 1 |
| Giri, AK; Khan, KA; Philipose, B; Singh, R | 1 |
| Landt, M; Smith, CH; Way, BA; Wilhite, TR | 1 |
| Blanco, M; Coello, J; Iturriaga, H; Maspoch, S; Pérez-Maseda, C | 1 |
| Aboul-Enein, HY; Baeyens, W; De Kruif, A; Deprez, P; Oda, H; Van Overbeke, A; Vander Weken, G | 1 |
| Abordo, EA; Bowden, K; Huntington, AP; Powell, SL | 1 |
| Dajani, EZ | 1 |
| el-Bary, AA; el-Nabarawi, MA; Mohamed, MI | 1 |
| Nakagawa, H; Shimizu, K; Yamada, K | 1 |
| Autret-Leca, E; Jonville-Béra, AP | 1 |
| de Villiers, MM; Gerber, JJ; Liebenberg, W; Malan, SF | 1 |
| Pedersen-Bjergaard, S; Rasmussen, KE | 1 |
| Courtauld, E; Donnelly, MT; Hawkey, CJ; Richardson, P; Stack, WA | 1 |
| Deninger, MJ; Schoenwald, RD | 1 |
| Allegretti, M; Bertini, R; Biordi, L; Caselli, G; Martinotti, S; Marullo, A; Mascagni, P; Sabbatini, V | 1 |
| Hercegová, A; Polonský, J; Sádecká, J | 1 |
| Mardones, C; Ríos, A; Valcárcel, M | 1 |
| Marrero, I; Olson, NZ; Sunshine, A; Tirado, S | 1 |
| Bujak-Gizycka, B; Kłys, M; Latacz, B; Skupień, E | 1 |
| Mason, JC; Patonay, G; Sowell, J; Strekowski, L | 1 |
| Cooper, S; Doyle, G; Jayawardena, S; Marrero, I; Olson, NZ; Otero, AM; Sunshine, A; Tirado, S | 1 |
| Schmoldt, A; Tsokos, M | 1 |
| Chiang, HN; Wang, LF; Wu, PC | 1 |
| Attwood, D; Bachynsky, J; Kawasaki, N; Kubo, W; Loebenberg, R; Miyazaki, S; Suzuki, S; Takahashi, A | 1 |
| Tanaka, Y | 1 |
| Abushoffa, AM; Crommen, J; Fillet, M; Hubert, P; Servais, AC | 1 |
| Bateman, SD; Erck, R; Li, T; Morris, KR; Wang, JJ | 1 |
| Kristl, A; Legen, I; Zakelj, S | 1 |
| Pina, ME; Salsa, T; Teixeira-Dias, JJ; Veiga, F | 1 |
| Gallagher, SJ; Harwood, J; Heard, CM; Maguire, PB | 1 |
| Goto, J; Kim, J; Kim, JH; Kim, KR; La, S | 1 |
| Balabanova, RM | 1 |
| Cowan, A; Raffa, RB; Tallarida, RJ | 1 |
| Cassely, A; Hoffmann, J; Mechref, Y; Novotny, MV | 1 |
| Bateman, SD; Guillot, MA; Morris, KR; Wang, JJ | 1 |
| Bensman, A; Dunan, O; Guigonis, V; Ulinski, T | 1 |
| Kobayashi, D; Kogo, T; Morimoto, Y; Numajiri, S; Shimamura, T; Tairabune, T; Ueda, H | 1 |
| Aguilar, C; Borrull, F; Calull, M; Macià, A | 1 |
| Kostrun, S; Kujundzić, N; Marković, S; Martić, M; Tatić, I | 1 |
| Bagheri, H; Lacroix, I; Lapeyre-Mestre, M; Montastruc, JL; Pathak, A | 1 |
| Bock, U; Haltner, E; Krause, W; Otto, J | 1 |
| Foster, GD; Thomas, PM | 1 |
| De Alencastro, LF; Grandjean, D; Tarradellas, J; Tauxe-Wuersch, A | 1 |
| Kronberg, L; Lindqvist, N; Tuhkanen, T | 1 |
| Blazević, N; Debeljak, Z; Petrović, M | 1 |
| Quintana, JB; Reemtsma, T; Weiss, S | 1 |
| Lin, AY; Reinhard, M | 1 |
| Araya, H; Hayashi, M; Nagao, S; Tomita, M | 1 |
| Corrigan, OI; Lane, ME; Levis, K; McDonald, GS | 1 |
| Fujii, M; Kokudai, M; Kondoh, M; Noda, S; Okada, H; Shibata, Y; Watanabe, Y | 1 |
| Chen, JS; Huang, SJ; Lin, SC; Lin, YJ; Peng, YS; Wang, LF; Wang, YM | 1 |
| Dawood, MY | 1 |
| Berger, MY; Damen, L; Koes, BW; Merlijn, V; Passchier, J; Verhagen, AP | 1 |
| Blanzat, M; Bordat, P; Consola, S; Garrigues, JC; Perez, E; Rico-Lattes, I | 1 |
| Lukosek, M; Nachajski, MJ; Zgoda, MM | 2 |
| Autret-Leca, E; Blum-Boisgard, C; Deligne, J; Giraudeau, B; Grimaldi, L; Jonville-Béra, AP | 1 |
| Hara, H; Kimura, K; Watanabe, Y | 1 |
| Chagti, KK; Giridhar, R; Halen, PK; Yadav, MR | 1 |
| Larsen, KL; Madsen, F; Woldum, HS | 1 |
| Babazadeh, M | 1 |
| Archibold, EF; Duan, P; Habicht, SC; Kenttämaa, HI; Vinueza, NR | 1 |
| Barri, T; Jönsson, JA; Karlsson, M; Trtić-Petrović, T | 1 |
| Kołodziejczyk, MK; Lukosek, M; Nachajski, MJ; Woskowicz, MH; Zgoda, MM | 1 |
| Molnár-Perl, I; Palkó, G; Sebok, A; Vasanits-Zsigrai, A; Záray, G | 1 |
| Bandettini, M; Bertelli, E; Caputi, S; Carraro, M; Garau, V; Levrini, L; Lörincz, A; Pelliccioni, GA; Rizzo, S; Salgarello, S; Szûcs, A | 1 |
| Asami, M; Fujiwara, J; Kunikane, S; Manabe, S; Matsuda, M; Simazaki, D | 1 |
| Ivanov, IT; Tsokeva, Z | 1 |
| Hochlowski, JE; Pan, JY; Searle, PA; Tu, NP; Wagenaar, FL | 1 |
| Akgoz, S; Arisoy, ES; Aygun, D; Celebi, S; Citak Kurt, AN; Hacimustafaoglu, M; Karali, Y; Seringec, M | 1 |
| Hosoya, K; Kaya, K; Kubo, T; Mori, T | 1 |
| Es'haghi, Z | 1 |
| Akural, EI; Alahuhta, S; Järvimäki, V; Länsineva, A; Niinimaa, A | 1 |
| Hardikar, MS | 1 |
| Angeletti, M; Censi, R; Di Martino, P; Gashi, Z; Gobetto, R; Malaj, L; Masic, A; Mozzicafreddo, M | 1 |
| Dowling, G; Fabbrocino, S; Gallo, P; Regan, L; Serpe, L | 1 |
| Ali, W; Rawlinson, CF; Williams, AC | 1 |
| Capomacchia, AC; Yuan, X | 1 |
| Kokki, H; Kokki, M | 1 |
| Barcelo, D; Budzinski, H; Castiglioni, S; de Alencastro, LF; Farre, M; Gans, O; Heath, E; Kosjek, T; Langford, K; Loos, R; Petrovic, M; Quintana, JB; Radjenović, J; Rocca, LM; Tsipi, D | 1 |
| Bui, TX; Choi, H | 1 |
| Helenkár, A; Molnár-Perl, I; Sebok, A; Vasanits-Zsigrai, A; Záray, G | 1 |
| Ezoddin, M; Hidalgo, M; Jönsson, JA; Larsson, E; Sagristà, E; Salvadó, V | 1 |
| Miranda, HF; Noriega, V; Prieto, JC; Sierralta, F | 1 |
| Dombi, A; Gajda-Schrantz, K; Illés, E; Mazellier, P; Megyeri, C; Szabó, RK | 1 |
| Hashim, NH; Khan, SJ | 1 |
| Hashim, NH; Khan, SJ; Nghiem, LD; Stuetz, RM | 1 |
| Unlü, B; van Leeuwen, JS; Vermeulen, NP; Vos, JC | 1 |
| Dobor, J; Varga, M; Záray, G | 1 |
| Gersberg, RM; Hua, T; Jinadasa, KB; Tan, SK; Zhang, DQ; Zhu, J | 1 |
| Chen, L; Duan, YP; Meng, XZ; Wen, ZH | 2 |
| Chuang, VT; Ito, T; Kaneko, K; Maruyama, T; Otagiri, M; Suenaga, A; Watanabe, H | 1 |
| Casely-Hayford, MA; Douroumis, D; Favretto, ME; Kallinteri, P; Khan, GM; Onyeagor, ND; Wahab, A | 1 |
| Amidon, GL; Garcia-Arieta, A; Langguth, P; Tsume, Y | 1 |
| Dickenson, ER; Drewes, JE; Hoppe-Jones, C | 1 |
| Kietzmann, M; Stahl, J; Wohlert, M | 1 |
| Chen, L; Duan, YP; Ke, RH; Meng, XZ; Wen, ZH | 1 |
| Almeida, B; Brito, D; Carvalho, G; Crespo, MT; Marques, R; Oehmen, A | 1 |
| Koç, FE; Senel, M | 1 |
| Bouchet, LM; de la Guardia, M; Delgado-Pérez, T; Galian, RE; Pérez-Prieto, J | 1 |
| Larsson, DG; Ramaswamy, BR; Sampath, S; Selvaraj, KK; Shanmugam, G | 1 |
| Dâas, A; Hamdaoui, O | 1 |
| Belsey, NA; Contreras-Rojas, LR; Garrett, NL; Guy, RH; Moger, J; Pickup-Gerlaugh, AJ; Price, GJ | 1 |
| Dong, YB; Kuang, X; Ma, Y; Su, H; Tang, B; Zhang, J | 1 |
| Jakimska, A; Kot-Wasik, A; Namieśnik, J; Reszczyńska, J; Śliwka-Kaszyńska, M | 1 |
| Galluzzi, KE; Stanos, SP | 1 |
| Jia, Y; Tan, J; Tang, J; Wang, Y; Xie, Q; Xu, C | 1 |
| Dawas-Massalha, A; Dosoretz, CG; Gur-Reznik, S; Lerman, S; Sabbah, I | 1 |
| Bursová, M; Cabala, R; Hložek, T | 1 |
| Amidon, GE; Amidon, GL; Krieg, BJ; Taghavi, SM | 1 |
| Gaš, B; Riesová, M; Svobodová, J; Tošner, Z; Ušelová, K; Zusková, I | 1 |
| Ademollo, N; Capri, S; Patrolecco, L | 1 |
| Boyer, TH; Huang, CH; Landry, KA; Sun, P | 1 |
| Caballo, C; Rubio, S; Sicilia, MD | 1 |
| Álvarez-Lueje, A; Toledo-Neira, C | 1 |
| Gjelstad, A; Pedersen-Bjergaard, S; Roldán-Pijuán, M | 1 |
| Akdeniz, A; Anzenbacher, P; Minami, T; Mosca, L | 1 |
| Chen, J; Huang, C; Li, Y; Wang, J; Wang, L; Yang, J | 1 |
| Hu, M; Li, J; Shi, ZG; Xu, L | 1 |
| Lyu, DY; Yan, XP; Yang, CX | 1 |
| Diogo, HP; Mora, E; Moura Ramos, JJ | 1 |
| Bendtsen, L; Derry, S; Moore, RA; Wiffen, PJ | 1 |
| An, S; He, L; Yang, L; Zhang, J; Zhang, L | 1 |
| de Moraes Del Lama, MPF; de Moraes, LAB; de Oliveira, ARM; Moreira, MB; Naal, RMZG; Nikolaou, S; Petta, T; Seuanes, GC | 1 |
| Affouard, F; Correia, NT; Ndjaka, JM; Ottou Abe, MT | 1 |
| Aguilar, C; Borrull, F; Calull, M; García-Vázquez, A | 1 |
| Endo, T; Harada, H; Kobayashi, M; Toyoda, Y | 1 |
| Lee, HK; Li, SF; Naing, NN | 1 |
| Bhuiyan, AKMMH; Waters, LJ | 1 |
| Arzenton, E; Bonaiuti, R; Bortolami, O; Capuano, A; Conforti, A; Donati, M; Lenti, MC; Leone, R; Moretti, U; Motola, D; Rafaniello, C; Sportiello, L; Vaccheri, A; Vannacci, A | 1 |
| Abadal Prades, M; Del Bas Rubia, M; Estrada Ferrer, O; Garcia Torralbo, EM; Heredia Budo, A; Hidalgo Grau, LA; Ruiz Edo, N; Suñol Sala, X | 1 |
| Olender, D; Pawełczyk, A; Sowa-Kasprzak, K; Zaprutko, L | 1 |
| Ahkola, HS; Herve, SH; Knuutinen, JS; Koistinen, J; Lahti, K; Lindholm-Lehto, PC; Vahtera, H | 1 |
| Jordan, J | 1 |
| Caminal, G; Mir-Tutusaus, JA; Sarrà, M | 1 |
| Du, G; Kang, L; Kathuria, H; Li, H; Ruan, X; Sun, Y | 1 |
| Kramulová, B; Marsik, P; Rezek, J; Tauchen, J; Vaněk, T; Židková, M | 1 |
| Wu, M; Ye, H; Zeng, B; Zhao, F | 1 |
| Burton, D; Jamieson, R; Khosravi, K; Price, GW; Zhang, Y | 1 |
| Allegretti, M; Antonosante, A; Aramini, A; Benedetti, E; Brandolini, L; Castelli, V; Catanesi, M; Cimini, A; Cristiano, L; d'Angelo, M; Giordano, A; Luini, A; Mayo, E; Parashuraman, S; Villa, S | 1 |
| Besancenot, V; Bignon, E; Drouot, G; Dumont, E; Eriksson, LA; Gattuso, H; Grandemange, S; Marazzi, M; Monari, A; Morell, C | 1 |
| Canotilho, J; Castro, RAE; Eusébio, MES; Machado, SMT; Maria, TMR | 1 |
| Garg, N; Kumar, R; Singh, A; Siril, PF | 1 |
| Chen, J; Huang, C; Jin, J; Li, Y; Peng, J; Wang, J; Yang, J | 1 |
| Hai, FI; Khan, SJ; McDonald, JA; Nghiem, LD; Nguyen, LN; Price, WE | 1 |
| Chen, J; Huang, C; Jin, J; Li, Y; Ma, H; Peng, J; Yang, J | 1 |
| Iwaki, M; Kawase, A; Kobayashi, Y; Ogiso, T; Shimada, H; Tanahashi, S | 1 |
| Abd Wahib, SM; Abdul Keyon, AS; Kamboh, MA; Sanagi, MM; Wan Ibrahim, WA | 1 |
| Cristina, RH; María Jesús, MV; Miguel Ángel, BL; Rut, FT | 1 |
| Bargelloni, L; Consolandi, G; d'Errico, G; Fattorini, D; Gorbi, S; Mezzelani, M; Milan, M; Regoli, F | 1 |
| Ask, KS; Gjelstad, A; Pedersen-Bjergaard, S; Øiestad, EL | 1 |
| Aggazzotti, G; Castiglioni, S; Fantuzzi, G; Predieri, G; Righi, E; Riva, F; Zuccato, E | 1 |
| Bandari, S; Dumpa, NR; Repka, MA; Sarabu, S; Zhang, F | 1 |
| Escuder-Gilabert, L; Martín-Biosca, Y; Medina-Hernández, MJ; Perez-Baeza, M; Sagrado, S | 1 |
| Araujo, M; Benevent, J; Bouilhac, C; Damase-Michel, C; Hurault-Delarue, C; Lacroix, I; Montastruc, JL; Petiot, D; Vayssière, C; Vidal, S | 1 |
| Bello-López, MÁ; López-Pérez, G; Martín-Valero, MJ; Román-Hidalgo, C | 1 |
| Alshana, U; Hassan, M | 1 |
| Aranda, N; Miranda, HF; Noriega, V; Poblete, P; Prieto, JC; Sierralta, F | 1 |
| Havadej, S; Holečková, B; Staničová, J; Uličný, J; Verebová, V; Želonková, K | 1 |
| Carrasco-Correa, EJ; Giesbers, M; Herrero-Martínez, JM; Simó-Alfonso, EF | 1 |
| Aydin, ME; Aydin, S; Ulvi, A | 1 |
| Bujacz, A; Sekula, B; Szymczak, I; Zielinski, K | 1 |
| Barlow, DJ; Jackson, PJM; Pysz, I; Rahman, KM; Thurston, DE | 1 |
| Chen, Y; Hao, C; Nie, W; Wang, L; Xu, P; Yin, Y | 1 |
| Barceló, D; López-Doval, JC; Rodríguez-Mozaz, S; Sabater, S; Serra-Compte, A | 1 |
| Collazzo, GC; Dotto, GL; Druzian, SP; Foletto, EL; Oliveira, LFS; Streit, AFM; Verdi, RS | 1 |
| Britch, SC; Craft, RM; Hewitt, KA | 1 |
| De Aramburu Mera, T; Ochando Díez-Canseco, M; Prados Castaño, M; Reguero Capilla, M | 1 |
| Bączek, T; Chung, DS; Jeong, S; Kwon, JY; Kwon, W; Miękus, N; Valdez, JE | 1 |
| Ahmed, F; Li, J; Mueller, JF; O'Brien, JW; Samanipour, S; Thai, PK; Thomas, KV; Tscharke, BJ; Yuan, Z | 1 |
| Chaturvedi, K; Dave, RH; Morris, KR; Shah, HS | 1 |
| Gálvez, R; Olmedo-Gaya, MV; Vallecillo, C; Vallecillo-Capilla, M; Vallecillo-Rivas, M | 1 |
| Drouza, C; Papagiouvannis, G; Petrou, A; Rekka, EA; Theodosis-Nobelos, P; Tziona, P | 1 |
| Bădulescu, M; Stefan-van Staden, RI; Ţuchiu, BM; van Staden, JF | 1 |
| Dogan, C; Kemanci, A; Oskay, A; Ozen, M; Seyit, M; Turkcuer, I; Uluturk, M; Yilmaz, A | 1 |
| Ni, J; Pan, B; Xu, N; Xu, X; Xu, Y | 1 |
| Du, G; Fang, Z; Gong, N; Lu, Y; Xing, C; Xing, W; Yu, H; Zhang, B | 1 |
| Alatawi, H; Albalawi, I; Alsefri, S; Hogan, A; Moore, E; O'Sullivan-Carroll, E; Wang, Y | 1 |
| Gorenflo, M; Saur, P; van den Anker, JN; van Dyk, M; Welzel, T; Ziesenitz, VC | 1 |
| Dorazilová, J; Dvořák, M; Kubáň, P; Ryšavá, L; Sedláček, P; Vojtová, L | 1 |
| Alfonsetti, M; Allegretti, M; Benedetti, E; Brandolini, L; Castelli, V; Catanesi, M; Cesta, MC; Cimini, A; Cocchiaro, P; Colagioia, S; d'Angelo, M; Giorgio, C; Tomassetti, M; Zippoli, M | 1 |
| Distefano, GG; Gambaro, A; Picone, M; Volpi Ghirardini, A; Zangrando, R | 1 |
| Ben Attig, J; Cañizares, P; Latrous, L; Lourdes Souza, F; Ríos, Á; Rodrigo, MA; Sáez, C; Zougagh, M | 1 |
| Jamieson, R; Lake, C; Price, GW; Shu, W | 1 |
| Toghrolian, A; Zadsirjan, S; Zargar, N | 1 |
| Masís-Mora, M; Méndez-Rivera, M; Montiel-Mora, JR; Ramírez-Morales, D; Rodríguez-Rodríguez, CE | 1 |
20 review(s) available for ibuprofen and ketoprofen
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Antiinflammatory drugs.
Topics: Adult; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Benzylidene Compounds; Child; Drug Evaluation; Female; Humans; Ibuprofen; Indenes; Indomethacin; Ketoprofen; Mefenamic Acid; Naproxen; Phenylacetates; Phenylbutazone; Pregnancy; Pregnancy Complications; Propionates; Tolmetin | 1977 |
[Drug therapy of ankylosing spondyloarthritis (Bechterew's disease)].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Apazone; Butadienes; Cyclophosphamide; Diclofenac; Drug Combinations; Drug Evaluation; Glycolates; Gold; Humans; Ibuprofen; Indomethacin; Ketoprofen; Levamisole; Naproxen; Oxyphenbutazone; Phenylbutazone; Salicylates; Spondylitis, Ankylosing; Sulindac | 1978 |
Non-steroidal and analgesic therapy in the elderly.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Apazone; Aspirin; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Diclofenac; Drug Hypersensitivity; Gastrointestinal Diseases; Hematologic Diseases; Humans; Ibuprofen; Indomethacin; Ketoprofen; Kidney Diseases; Kinetics; Naproxen; Phenylbutazone; Piroxicam; Salicylates; Thiazines | 1986 |
Non-steroidal anti-inflammatory drugs (NSAID'S) as analgesics in dentistry - a review.
Topics: Analgesics; Anti-Inflammatory Agents; Aspirin; Dental Care; Diflunisal; Humans; Ibuprofen; Indomethacin; Ketoprofen; Oxyphenbutazone; Pain, Postoperative; Phenylbutazone | 1983 |
Update on ibuprofen for rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Piroxicam; Sulindac; Thiazines; Tolmetin | 1984 |
Calculation of inversion half-lives of aryl propionic acid class nonsteroidal antiinflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Fenoprofen; Half-Life; Humans; Ibuprofen; Ketoprofen; Models, Biological; Stereoisomerism | 1996 |
Use of carprofen for the treatment of pain and inflammation in dogs.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carbazoles; Clonixin; Cyclooxygenase Inhibitors; Dog Diseases; Dogs; Ibuprofen; Indomethacin; Ketoprofen; Meclofenamic Acid; Meloxicam; Naproxen; Osteoarthritis; Pain; Phenylbutazone; Piroxicam; Thiazines; Thiazoles | 1997 |
Method development of enantiomer separations by affinity capillary electrophoresis, cyclodextrin electrokinetic chromatography and capillary electrophoresis-mass spectrometry.
Topics: Chromatography, Micellar Electrokinetic Capillary; Cyclodextrins; Electrophoresis, Capillary; Ibuprofen; Ketoprofen; Mass Spectrometry; Static Electricity; Stereoisomerism; Vanilmandelic Acid; Warfarin | 2002 |
[Current concepts of pharmacotherapy in rheumatoid arthritis].
Topics: Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cyclooxygenase Inhibitors; Cyclophosphamide; Cyclosporine; Double-Blind Method; Drug Therapy, Combination; Feasibility Studies; Female; Glucocorticoids; Humans; Ibuprofen; Immunosuppressive Agents; Isoxazoles; Ketoprofen; Leflunomide; Male; Methotrexate; Prednisolone; Prognosis; Randomized Controlled Trials as Topic; Risk Factors; Sulfasalazine; Time Factors | 2003 |
Primary dysmenorrhea: advances in pathogenesis and management.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Contraceptives, Oral, Combined; Decision Trees; Dysmenorrhea; Female; Humans; Ibuprofen; Ketoprofen; Naproxen | 2006 |
Is any one analgesic superior for episodic tension-type headache?
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diclofenac; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Ibuprofen; Ketoprofen; Naproxen; Nonprescription Drugs; Secondary Prevention; Tension-Type Headache; Treatment Outcome | 2006 |
Chiral non-steroidal anti-inflammatory drugs--a review.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Etodolac; Humans; Ibuprofen; Ketoprofen; Tromethamine | 2008 |
Topical therapies in the management of chronic pain.
Topics: Administration, Cutaneous; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Chronic Pain; Diclofenac; Humans; Ibuprofen; Irritants; Ketoprofen; Lidocaine; Musculoskeletal Pain; Neoplasms; Neuralgia; Neuralgia, Postherpetic; Osteoarthritis, Knee; Palliative Care | 2013 |
Ibuprofen for acute treatment of episodic tension-type headache in adults.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Cyclooxygenase Inhibitors; Diclofenac; Humans; Ibuprofen; Ketoprofen; Naproxen; Numbers Needed To Treat; Pain Measurement; Piroxicam; Randomized Controlled Trials as Topic; Tension-Type Headache; Time Factors | 2015 |
Topical NSAIDs for Acute Musculoskeletal Pain in Adults.
Topics: Acute Pain; Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Ibuprofen; Ketoprofen; Musculoskeletal Pain; Treatment Outcome | 2016 |
Efficacy and safety of over-the-counter analgesics for primary dysmenorrhea: A network meta-analysis.
Topics: Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Dysmenorrhea; Female; Humans; Ibuprofen; Ketoprofen; Middle Aged; Naproxen; Network Meta-Analysis; Nonprescription Drugs; Treatment Outcome; Young Adult | 2020 |
Efficacy and Safety of NSAIDs in Infants: A Comprehensive Review of the Literature of the Past 20 Years.
Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Child; Chronic Disease; Diclofenac; Flurbiprofen; Humans; Ibuprofen; Infant; Ketoprofen; Ketorolac; Meloxicam; Naproxen; Niflumic Acid; Pain | 2022 |
30 trial(s) available for ibuprofen and ketoprofen
| Article | Year |
|---|---|
Evaluation of analgesic action and efficacy of antirheumatic drugs. Study of 10 drugs in 684 patients with rheumatoid arthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Flurbiprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Mefenamic Acid; Pain; Phenylacetates; Placebos; Prednisone; Salicylates | 1976 |
Double-blind, multi-centre parallel trial of ketoprofen and ibuprofen in the treatment of rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Benzophenones; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Ibuprofen; Ketoprofen; Male; Middle Aged; Phenylpropionates | 1977 |
[Results of a double-blind controlled study of the comparative effects of ketoprofen and ibuprofen in orthopedic patients].
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Humans; Ibuprofen; Joint Diseases; Ketoprofen; Male; Middle Aged; Phenylpropionates; Spinal Diseases | 1978 |
A comparative trial of ketoprofen and ibuprofen in patients with rheumatic disease.
Topics: Clinical Trials as Topic; Humans; Ibuprofen; Ketoprofen; Phenylpropionates; Rheumatic Diseases | 1978 |
A review of upper-gastrointestinal effects of the newer nonsteroidal antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Evaluation; Fenoprofen; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Ibuprofen; Ketoprofen; Naproxen; Phenylbutazone; Registries; Sulindac; Tolmetin | 1979 |
A double-blind cross-over evaluation of ketoprofen (Orudis) and ibuprofen in the management of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Ibuprofen; Ketoprofen; Male; Middle Aged; Phenylpropionates; Placebos | 1979 |
Aspirin stimulates insulin and glucagon secretion and increases glucose tolerance in normal and diabetic subjects.
Topics: Adult; Aged; Aspirin; Blood Glucose; Diabetes Mellitus; Glucagon; Glucose; Humans; Ibuprofen; Insulin; Ketoprofen; Middle Aged; Placebos | 1978 |
Four new anti-inflammatory drugs: responses and variations.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Fenoprofen; Gastrointestinal Diseases; Humans; Ibuprofen; Ketoprofen; Naproxen; Pain | 1976 |
Ketoprofen - clinical efficacy.
Topics: Acetaminophen; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Aspirin; Benzophenones; Clinical Trials as Topic; Gout; Humans; Ibuprofen; Indomethacin; Ketoprofen; Phenylbutazone; Placebos; Sciatica; Spondylitis, Ankylosing | 1976 |
Endoscopic evaluation of the effect of ketoprofen, ibuprofen and aspirin on the gastroduodenal mucosa.
Topics: Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Double-Blind Method; Female; Gastric Mucosa; Gastroscopy; Humans; Ibuprofen; Ketoprofen; Male | 1992 |
The effect of magnesium hydroxide on the oral absorption of ibuprofen, ketoprofen and diclofenac.
Topics: Adult; Biological Availability; Diclofenac; Female; Humans; Ibuprofen; Intestinal Absorption; Ketoprofen; Magnesium Hydroxide | 1991 |
Ketoprofen, ibuprofen, and placebo in the treatment of primary dysmenorrhea: a double-blind crossover comparison.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea; Female; Humans; Ibuprofen; Ketoprofen; Pain; Phenylpropionates; Random Allocation | 1988 |
Update on ibuprofen for rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Piroxicam; Sulindac; Thiazines; Tolmetin | 1984 |
Comparison of the analgesic effect of ten nonsteroidal anti-inflammatory drugs.
Topics: Adult; Aged; Analgesics; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Carbazoles; Diclofenac; Female; Humans; Ibuprofen; Indomethacin; Ketoprofen; Male; Middle Aged; Naproxen; ortho-Aminobenzoates; Quinazolines | 1984 |
Comparison ketoprofen, ibuprofen and naproxen sodium in the treatment of tension-type headache.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Ibuprofen; Ketoprofen; Male; Middle Aged; Naproxen; Pain Measurement; Prospective Studies; Tension-Type Headache | 1995 |
Effectiveness of various medications on postoperative pain following complete instrumentation.
Topics: Acetaminophen; Adult; Analysis of Variance; Chi-Square Distribution; Codeine; Dental Anxiety; Erythromycin; Humans; Ibuprofen; Ketoprofen; Methylprednisolone; Pain Measurement; Pain, Postoperative; Penicillins; Regression Analysis; Root Canal Irrigants; Root Canal Therapy; Salicylates; Salicylic Acid; Surveys and Questionnaires; Time Factors; Toothache | 1994 |
Effectiveness of various medications on postoperative pain following root canal obturation.
Topics: Acetaminophen; Adult; Aged; Analysis of Variance; Chi-Square Distribution; Codeine; Erythromycin; Female; Humans; Ibuprofen; Ketoprofen; Male; Methylprednisolone; Middle Aged; Pain Measurement; Pain, Postoperative; Penicillins; Prospective Studies; Regression Analysis; Root Canal Obturation; Salicylates; Salicylic Acid | 1994 |
Self-medication of a single headache episode with ketoprofen, ibuprofen or placebo, home-monitored with an electronic patient diary.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Headache; Humans; Ibuprofen; Ketoprofen; Placebos; Self Medication | 1996 |
[Topical treatment of soft tissue rheumatism and athletic injuries. Effectiveness and tolerance of a new ketoprofen gel].
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Athletic Injuries; Double-Blind Method; Female; Fibromyalgia; Gels; Humans; Ibuprofen; Ketoprofen; Male; Middle Aged; Pain Measurement; Polymyalgia Rheumatica; Treatment Outcome | 1996 |
Effects of ketoprofen and ibuprofen on platelet aggregation and prostanoid formation in man.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Female; Humans; Ibuprofen; Ketoprofen; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandins; Thromboxane B2 | 1996 |
Dose-dependent effects of ketoprofen on the human gastric mucosa in comparison with ibuprofen.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Gastric Mucosa; Humans; Ibuprofen; Ketoprofen; Male; Prostaglandins; Self Medication; Stomach Ulcer; Therapeutic Equivalency | 2000 |
Onset and duration of analgesia for low-dose ketoprofen in the treatment of postoperative dental pain.
Topics: Adolescent; Adult; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Ibuprofen; Ketoprofen; Male; Pain, Postoperative; Time Factors; Tooth Extraction | 1998 |
Onset of analgesia for liquigel ibuprofen 400 mg, acetaminophen 1000 mg, ketoprofen 25 mg, and placebo in the treatment of postoperative dental pain.
Topics: Abdominal Pain; Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Gels; Headache; Humans; Ibuprofen; Ketoprofen; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Time Factors; Tooth Extraction; Treatment Outcome | 2001 |
[Comparative in vitro and in vivo studies on the permeation and penetration of ketoprofen and ibuprofen in human skin].
Topics: Administration, Topical; Adult; Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Diffusion Chambers, Culture; Female; Gels; Humans; Ibuprofen; In Vitro Techniques; Ketoprofen; Permeability; Skin Absorption | 2004 |
Antipyretic effect of ketoprofen.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Fever; Humans; Ibuprofen; Infant; Ketoprofen; Male; Time Factors; Treatment Outcome | 2009 |
Effects of combination treatment with ketoprofen 100 mg + acetaminophen 1000 mg on postoperative dental pain: a single-dose, 10-hour, randomized, double-blind, active- and placebo-controlled clinical trial.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Deglutition; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Ketoprofen; Male; Oral Surgical Procedures; Pain Measurement; Pain, Postoperative; Time Factors; Tooth, Impacted; Treatment Outcome; Young Adult | 2009 |
Ketoprofen versus paracetamol (acetaminophen) or ibuprofen in the management of fever: results of two randomized, double-blind, double-dummy, parallel-group, repeated-dose, multicentre, phase III studies in children.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Double-Blind Method; Female; Fever; Humans; Ibuprofen; Infant; Ketoprofen; Male; Prospective Studies; Treatment Outcome | 2010 |
ANALGESIC EFFICACY OF TRAMADOL/DEXKETOPROFEN VS IBUPROFEN AFTER IMPACTED LOWER THIRD MOLAR EXTRACTION: A RANDOMIZED CONTROLLED CLINICAL TRIAL.
Topics: Analgesics; Double-Blind Method; Drug Combinations; Humans; Ibuprofen; Ketoprofen; Molar, Third; Pain, Postoperative; Tooth Extraction; Tramadol; Tromethamine | 2021 |
Comparative evaluation of the effectiveness of intravenous paracetamol, dexketoprofen and ibuprofen in acute low back pain.
Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Humans; Ibuprofen; Ketoprofen; Low Back Pain; Tromethamine | 2022 |
Analgesic Efficacy of Ketoprofen Transdermal Patch versus Ibuprofen Oral Tablet on Postendodontic Pain in Patients with Irreversible Pulpitis: A Randomized Clinical Trial.
Topics: Analgesics; Double-Blind Method; Humans; Ibuprofen; Ketoprofen; Pain, Postoperative; Pulpitis; Transdermal Patch | 2023 |
267 other study(ies) available for ibuprofen and ketoprofen
| Article | Year |
|---|---|
Bulky amine analogues of ketoprofen: potent antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Edema; Indicators and Reagents; Ketoprofen; Magnetic Resonance Spectroscopy; Male; Phenylpropionates; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1984 |
Interactions of nonsteroidal anti-inflammatory drugs with rat renal organic anion transporter, OAT-K1.
Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Carrier Proteins; Drug Interactions; Indomethacin; Ketoprofen; Kidney; Male; Methotrexate; Rats; Rats, Wistar; Tetraethylammonium Compounds | 1997 |
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes.
Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis | 1999 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1.
Topics: Adenine; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Biological Transport; Carrier Proteins; Humans; Kidney; Organophosphonates; Structure-Activity Relationship | 2000 |
Interaction between methotrexate and nonsteroidal anti-inflammatory drugs in organic anion transporter.
Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Carrier Proteins; Kinetics; Methotrexate; Oocytes; Probenecid; Uricosuric Agents; Xenopus laevis | 2000 |
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water | 2001 |
Comparative inhibitory effects of different compounds on rat oatpl (slc21a1)- and Oatp2 (Slc21a5)-mediated transport.
Topics: Algorithms; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antitubercular; Antimalarials; Biological Transport, Active; Digoxin; Enzyme Inhibitors; Estradiol; Ibuprofen; LLC-PK1 Cells; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Quinidine; Quinine; Rats; Rifampin; Swine | 2002 |
Characterization of methotrexate transport and its drug interactions with human organic anion transporters.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cells, Cultured; Humans; Indomethacin; Kinetics; Liver-Specific Organic Anion Transporter 1; Methotrexate; Mice; Mice, Transgenic; Nerve Tissue Proteins; Organic Anion Transporters, Sodium-Independent; Phenylbutazone; Potassium Channels; Potassium Channels, Tandem Pore Domain; Probenecid | 2002 |
The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs.
Topics: Adenosine Triphosphate; Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cell Line; Cell Membrane; Diffusion; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Humans; Insecta; Multidrug Resistance-Associated Proteins; Prostaglandins; Prostaglandins A; Prostaglandins F; Ribosomal Proteins; RNA Interference; RNA, Small Interfering; Thromboxane B2; Time Factors | 2003 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Synthesis and pharmacological evaluation of amide conjugates of NSAIDs with L-cysteine ethyl ester, combining potent antiinflammatory and antioxidant properties with significantly reduced gastrointestinal toxicity.
Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cholesterol; Cysteine; Drug Evaluation; Gastrointestinal Diseases; Lipoproteins, LDL; Mice; Rats; Triglycerides | 2004 |
Novel cyclooxygenase-1 inhibitors discovered using affinity fingerprints.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Combinatorial Chemistry Techniques; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Design; Drug Evaluation, Preclinical; Ibuprofen; Inhibitory Concentration 50; Isoenzymes; Models, Molecular; Models, Theoretical; Molecular Structure; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Quantitative Structure-Activity Relationship | 2004 |
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism | 2005 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Nonsteroidal anti-inflammatory drugs and their analogues as inhibitors of aldo-keto reductase AKR1C3: new lead compounds for the development of anticancer agents.
Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Drug Design; Enzyme Inhibitors; Humans; Hydroxyprostaglandin Dehydrogenases; Molecular Structure; Tumor Cells, Cultured | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Interaction of ibuprofen and other structurally related NSAIDs with the sodium-coupled monocarboxylate transporter SMCT1 (SLC5A8).
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cation Transport Proteins; Cell Line; Dose-Response Relationship, Drug; Fenoprofen; Humans; Ibuprofen; Membrane Potentials; Molecular Structure; Monocarboxylic Acid Transporters; Niacin; Oocytes; Propionates; Sodium; Structure-Activity Relationship; Transfection; Xenopus laevis | 2006 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Towards the first inhibitors of trihydroxynaphthalene reductase from Curvularia lunata: synthesis of artificial substrate, homology modelling and initial screening.
Topics: Amino Acid Sequence; Ascomycota; Benzopyrans; Enzyme Inhibitors; Fungal Proteins; Melanins; Models, Molecular; Molecular Sequence Data; Oxidoreductases Acting on CH-CH Group Donors; Recombinant Proteins; Structural Homology, Protein; Substrate Specificity | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence | 2010 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney | 2011 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Prediction of in vivo hepatic clearance and half-life of drug candidates in human using chimeric mice with humanized liver.
Topics: Animals; Cells, Cultured; Child, Preschool; Chimera; Cytochrome P-450 Enzyme System; Drug Evaluation, Preclinical; Drugs, Investigational; Female; Half-Life; Hepatocytes; Humans; Immunomagnetic Separation; Liver; Male; Metabolic Clearance Rate; Mice; Mice, SCID; Recombinant Proteins; Species Specificity; Urokinase-Type Plasminogen Activator | 2012 |
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship | 2012 |
Modified acidic nonsteroidal anti-inflammatory drugs as dual inhibitors of mPGES-1 and 5-LOX.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Cell Line; Humans; Indomethacin; Intramolecular Oxidoreductases; Lipoxygenase Inhibitors; Microsomes; Prostaglandin-E Synthases; Pyrazoles; Structure-Activity Relationship; Sulfonamides | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
Lysosomal sequestration (trapping) of lipophilic amine (cationic amphiphilic) drugs in immortalized human hepatocytes (Fa2N-4 cells).
Topics: Adrenergic beta-Antagonists; Amines; Ammonium Chloride; Antidepressive Agents, Tricyclic; Atorvastatin; Cell Line, Transformed; Diuretics; Hepatocytes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imipramine; Lysosomes; Monensin; Nigericin; Propranolol; Pyrroles | 2013 |
High analgesic and anti-inflammatory in vivo activities of six new hybrids NSAIAs tetrahydropyran derivatives.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Mice; Molecular Structure; Motor Activity; Pyrans | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Characterization of two distinct modes of drug binding to human intestinal fatty acid binding protein.
Topics: Fatty Acid-Binding Proteins; Fluorescent Dyes; Humans; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Spectrometry, Fluorescence | 2014 |
Propyphenazone-based analogues as prodrugs and selective cyclooxygenase-2 inhibitors.
Topics: | 2014 |
Inhibition of FAAH, TRPV1, and COX2 by NSAID-serotonin conjugates.
Topics: Amidohydrolases; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Flurbiprofen; Humans; Serotonin; TRPV Cation Channels | 2014 |
Effect of new hybrids based on 5,16-pregnadiene scaffold linked to an anti-inflammatory drug on the growth of a human astrocytoma cell line (U373).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Humans; Molecular Structure; Pregnadienes; Sulindac; Time Factors | 2015 |
Synthesis and Evaluation of Novel Erlotinib-NSAID Conjugates as More Comprehensive Anticancer Agents.
Topics: | 2015 |
Esters of some non-steroidal anti-inflammatory drugs with cinnamyl alcohol are potent lipoxygenase inhibitors with enhanced anti-inflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cinnamates; Edema; Esters; Glycine max; Hyperlipidemias; Indoleacetic Acids; Lipoxygenase Inhibitors; Polyethylene Glycols; Propanols; Propionates; Rats; Thioctic Acid | 2015 |
Amides of non-steroidal anti-inflammatory drugs with thiomorpholine can yield hypolipidemic agents with improved anti-inflammatory activity.
Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholesterol; Cholesterol, LDL; Edema; Hyperlipidemias; Hypolipidemic Agents; Morpholines; Rats; Triglycerides | 2016 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Non-steroidal Anti-inflammatory Drugs Are Caspase Inhibitors.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Caspase Inhibitors; Caspases; Caspases, Initiator; Cell Line; Cell Survival; High-Throughput Screening Assays; Humans; Ibuprofen; Inhibitory Concentration 50; Ketorolac; Naproxen; Small Molecule Libraries; Substrate Specificity | 2017 |
Synthesis and biological properties of aryl methyl sulfones.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Carrageenan; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Edema; Humans; Male; Mice; Models, Molecular; Molecular Structure; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Structure-Activity Relationship; Sulfones; Thermodynamics | 2018 |
Bioisosteric Development of Multitarget Nonsteroidal Anti-Inflammatory Drug-Carbonic Anhydrases Inhibitor Hybrids for the Management of Rheumatoid Arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Carbonic Anhydrase Inhibitors; Cyclooxygenase Inhibitors; Drug Design; Drug Development; Humans; Male; Molecular Dynamics Simulation; Pain; Rats; Rats, Sprague-Dawley | 2020 |
Diflunisal Derivatives as Modulators of ACMS Decarboxylase Targeting the Tryptophan-Kynurenine Pathway.
Topics: Bacterial Proteins; Binding Sites; Biosynthetic Pathways; Carboxy-Lyases; Catalytic Domain; Crystallography, X-Ray; Diflunisal; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kynurenine; Molecular Docking Simulation; NAD; Pseudomonas fluorescens; Structure-Activity Relationship; Tryptophan | 2021 |
Acute erosive gastritis induced by aspirin, ketoprofen, ibuprofen, and naproxen: its prevention by metiamide and cimetidine.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Mucosa; Gastritis; Guanidines; Histamine H2 Antagonists; Ibuprofen; Imidazoles; Ketoprofen; Male; Metiamide; Naproxen; Rats; Thiourea | 1977 |
Prostaglandin synthetase systems in rat and rabbit renal medulla and inhibition by non-steroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Ibuprofen; Indomethacin; Ketoprofen; Kidney; Kidney Medulla; Male; Microsomes; Phenylbutazone; Prostaglandins E; Prostaglandins F; Rabbits; Rats | 1977 |
The new antirheumatic drugs.
Topics: Anti-Inflammatory Agents; Fenoprofen; Flufenamic Acid; Humans; Ibuprofen; Ketoprofen; Mefenamic Acid; Naproxen; Penicillamine; Phenylacetates; Rheumatic Diseases; Salicylates | 1975 |
Old and new pharmaceutical non-steroidal compounds prescribed for the management of patients with rheumatic diseases.
Topics: Anti-Inflammatory Agents; Fenoprofen; Humans; Ibuprofen; Ketoprofen; Naproxen; Rheumatic Diseases; Sulindac; Tolmetin | 1979 |
[Comparative study of the gastroduodenal tolerability of some non-steroid drugs with analgesic-anti-inflammatory action].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Digestive System; Female; Humans; Ibuprofen; Joint Diseases; Ketoprofen; Male; Middle Aged | 1979 |
Inhibition of human leucocytes locomotion by anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Cell Movement; Chemotaxis, Leukocyte; Depression, Chemical; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Neutrophils; Salicylates | 1979 |
Bioavailability of powdered inclusion compounds of nonsteroidal antiinflammatory drugs with beta-cyclodextrin in rabbits and dogs.
Topics: Animals; Anti-Inflammatory Agents; Biological Availability; Dextrins; Dogs; Flufenamic Acid; Ibuprofen; Indomethacin; Ketoprofen; Powders; Rabbits; Starch | 1978 |
The identification of ibuprofen and analogues in urine by pyrolysis gas chromatography mass spectrometry.
Topics: Anti-Inflammatory Agents; Chromatography, Gas; Fenoprofen; Humans; Ibuprofen; Ketoprofen; Mass Spectrometry; Naproxen; Propionates | 1978 |
Some effects of non-steroidal anti-inflammatory drugs on leucocyte migration.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Cell Movement; Edema; Fenoprofen; Ibuprofen; Indomethacin; Ketoprofen; Leukocytes; Male; Methotrexate; Naproxen; Phenylbutazone; Pleurisy; Rats | 1976 |
Relationship between the inhibitory activity on 'RCS' and prostaglandins synthesis and the anti-inflammatory activity of ketoprofen and several other non-steroidal anti-inflammatory agents.
Topics: Abscess; Animals; Anti-Inflammatory Agents; Aorta; Arachidonic Acids; Aspirin; Benzophenones; Colon; Guinea Pigs; Hydroxy Acids; Ibuprofen; In Vitro Techniques; Indomethacin; Ketoprofen; Lung; Muscle Contraction; Naproxen; Phenylbutazone; Prostaglandin Antagonists; Prostaglandins; Pyrans | 1976 |
Pure enantiomers of 2-arylpropionic acids: tools in pain research and improved drugs in rheumatology.
Topics: Animals; Humans; Ibuprofen; Ketoprofen; Pain; Propionates; Research; Rheumatic Diseases; Stereoisomerism | 1992 |
Enantiospecific gas chromatographic-mass spectrometric procedure for the determination of ketoprofen and ibuprofen in synovial fluid and plasma: application to protein binding studies.
Topics: Gas Chromatography-Mass Spectrometry; Humans; Ibuprofen; Ketoprofen; Protein Binding; Reference Values; Reproducibility of Results; Stereoisomerism; Synovial Fluid | 1992 |
Inhibition of aromatic amino acid decarboxylase by a group of non-steroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aromatic Amino Acid Decarboxylase Inhibitors; Butyrates; Fenoprofen; Ibuprofen; In Vitro Techniques; Ketoprofen; Liver; ortho-Aminobenzoates; Rats; Structure-Activity Relationship | 1992 |
Inhibition kinetics of hepatic microsomal long chain fatty acid-CoA ligase by 2-arylpropionic acid non-steroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Coenzyme A Ligases; Fenoprofen; Ibuprofen; Ketoprofen; Kinetics; Male; Microsomes, Liver; Naproxen; Palmitoyl Coenzyme A; Rats; Rats, Inbred Strains; Repressor Proteins; Saccharomyces cerevisiae Proteins; Stereoisomerism; Substrate Specificity; Triglycerides | 1992 |
Metabolic chiral inversion of 2-arylpropionates in rat H4IIE and human Hep G2 hepatoma cells. Relationship to in vivo metabolism.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biotransformation; Flurbiprofen; Humans; Ibuprofen; Ketoprofen; Rats; Species Specificity; Stereoisomerism; Tumor Cells, Cultured | 1992 |
Inhibition of colon carcinogenesis by prostaglandin synthesis inhibitors and related compounds.
Topics: Animals; Azoxymethane; Colonic Neoplasms; Glycyrrhetinic Acid; Ibuprofen; Ketoprofen; Male; Piroxicam; Random Allocation; Rats; Rats, Inbred F344 | 1992 |
The efficacy and safety of ketoprofen in postsurgical dental pain.
Topics: Double-Blind Method; Humans; Ibuprofen; Ketoprofen; Molar, Third; Pain Measurement; Pain, Postoperative; Random Allocation; Safety; Tooth Extraction; Tooth, Impacted | 1991 |
Improved in vitro antigen-specific antibody synthesis in two patients with common variable immunodeficiency taking an oral cyclooxygenase and lipoxygenase inhibitor (ketoprofen).
Topics: Administration, Oral; Adolescent; Adult; Antibody Formation; B-Lymphocytes; Cell Differentiation; Child; Cyclooxygenase Inhibitors; Female; Humans; Ibuprofen; Immunologic Deficiency Syndromes; Ketoprofen; Lipoxygenase Inhibitors; Lymphocyte Activation; Male; Middle Aged; Mitogens; Naproxen | 1991 |
Stereoselective high-performance liquid chromatographic determination of ketoprofen, ibuprofen and fenoprofen in plasma using a chiral alpha 1-acid glycoprotein column.
Topics: 1-Propanol; Chromatography, High Pressure Liquid; Fenoprofen; Humans; Ibuprofen; Ketoprofen; Orosomucoid; Stereoisomerism | 1990 |
A method to predict the percutaneous permeability of various compounds: shed snake skin as a model membrane.
Topics: Animals; Cell Membrane Permeability; Hydrocortisone; Ibuprofen; Indomethacin; Ketoprofen; Models, Biological; Molecular Weight; Naproxen; Particle Size; Progesterone; Skin; Snakes | 1990 |
Inhibition of human periodontal prostaglandin E2 synthesis with selected agents.
Topics: Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dinoprostone; Eicosapentaenoic Acid; Flurbiprofen; Humans; Ibuprofen; Ketoprofen; Meclofenamic Acid; Naproxen; Periodontitis; Periodontium; Vitamin E | 1990 |
Study on the in vitro assay method for evaluating the inhibitory effect of various substances on the production of plasma kallikrein.
Topics: Aminopyrine; Aspirin; Humans; Ibuprofen; Indomethacin; Kallikreins; Ketoprofen; Kinetics; Kinins; Morphine; Pentazocine; Prekallikrein | 1989 |
Chromatographic approaches to the quality control of chiral propionate anti-inflammatory drugs and herbicides.
Topics: 2-Methyl-4-chlorophenoxyacetic Acid; 2,4-Dichlorophenoxyacetic Acid; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry; Chromatography, Gas; Flurbiprofen; Herbicides; Ibuprofen; Ketoprofen; Quality Control; Stereoisomerism | 1989 |
Acute renal failure associated with acute pyelonephritis and consumption of non-steroidal anti-inflammatory drugs.
Topics: Acute Kidney Injury; Adult; Aged; Anti-Inflammatory Agents; Apazone; Female; Humans; Ibuprofen; Ketoprofen; Middle Aged; Naproxen; Pyelonephritis | 1986 |
The history of diclofenac.
Topics: Chemical Phenomena; Chemistry; Diclofenac; Humans; Hydrogen-Ion Concentration; Ibuprofen; Indenes; Indomethacin; Ketoprofen; Naproxen; Phenylbutazone; Piroxicam; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship; Thiazines | 1986 |
The history of diclofenac.
Topics: Diclofenac; History, 20th Century; Ibuprofen; Ketoprofen; Models, Molecular; Naproxen; Phenylbutazone; Piroxicam; Solubility; Structure-Activity Relationship; Thiazines | 1985 |
Effects of some anti-inflammatory drugs on 12 blood constituents: protocol for the study of in vivo effects of drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Blood Chemical Analysis; Blood Urea Nitrogen; Cholesterol; Creatinine; Diclofenac; Humans; Ibuprofen; Indomethacin; Iron; Ketoprofen; Prospective Studies; Retrospective Studies; Serum Albumin; Time Factors; Triglycerides; Uric Acid | 1985 |
Diclofenac in the treatment of painful joints and traumatic tendinitis (including strains and sprains): a brief review.
Topics: Diclofenac; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Joint Diseases; Ketoprofen; Naproxen; Pain; Sprains and Strains; Tendinopathy | 1985 |
Poisoning after overdose with non-steroidal anti-inflammatory drugs.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Child, Preschool; Diflunisal; Female; Fenoprofen; Feprazone; Humans; Ibuprofen; Indomethacin; Ketoprofen; London; Male; Mefenamic Acid; Naproxen; Oxyphenbutazone; Phenylbutazone; Piroxicam; Thiazines; Tolmetin | 1984 |
Renal papillary necrosis following regular consumption of non-steroidal anti-inflammatory drugs.
Topics: Aged; Anti-Inflammatory Agents; Humans; Ibuprofen; Indomethacin; Ketoprofen; Kidney Papillary Necrosis; Male; Middle Aged; Naproxen; Osteoarthritis | 1982 |
Oral antipyretic therapy evaluation of the propionic acid derivatives ibuprofen, ketoprofen, fenoprofen and naproxen.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Fenoprofen; Fever; Ibuprofen; Ketoprofen; Naproxen | 1980 |
[In vitro studies on the rates of intestinal absorption of sparsely soluble drugs of different particle size].
Topics: Animals; Chloramphenicol; Ibuprofen; Intestinal Absorption; Ketoprofen; Membranes, Artificial; Models, Biological; Particle Size; Phenylpropionates; Solubility; Structure-Activity Relationship; Sulfadimethoxine | 1980 |
In vitro release of ketoprofren and ibuprofen from viscoelastic gels.
Topics: Elasticity; Excipients; Gels; Ibuprofen; Ketoprofen; Viscosity | 1995 |
Antimicrobial activities of N-acetylcysteine and some non-steroidal antiinflammatory drugs.
Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Candida albicans; Escherichia coli; Humans; Ibuprofen; Infant, Newborn; Ketoprofen; Microbial Sensitivity Tests; Staphylococcus | 1993 |
The determination of non-steroidal antiinflammatory drugs in pharmaceuticals by capillary zone electrophoresis and micellar electrokinetic capillary chromatography.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Buffers; Calibration; Chemistry, Pharmaceutical; Chromatography; Diclofenac; Dosage Forms; Electrophoresis; Ibuprofen; Indomethacin; Ketoprofen; Micelles; Piroxicam; Reference Standards; Regression Analysis; Reproducibility of Results | 1994 |
Metabolic chiral inversion of 2-arylpropionates in different tumor cell lines.
Topics: Animals; Carcinoma, Hepatocellular; Cell Count; Culture Media; Flurbiprofen; Humans; Ibuprofen; Ketoprofen; Liver Neoplasms; Liver Neoplasms, Experimental; Propionates; Rats; Species Specificity; Stereoisomerism; Tumor Cells, Cultured | 1993 |
Stereoselectivity of biliary excretion of 2-arylpropionates in rats.
Topics: Animals; Bile; Flurbiprofen; Ibuprofen; Injections, Intravenous; Ketoprofen; Male; Rats; Rats, Sprague-Dawley; Stereoisomerism | 1993 |
Induction of cytochrome P-450 BM-3 (CYP 102) by non-steroidal anti-inflammatory drugs in Bacillus megaterium.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacillus megaterium; Bacterial Proteins; Base Sequence; Cytochrome P-450 Enzyme System; Enzyme Induction; Gene Expression; Ibuprofen; Indomethacin; Ketoprofen; Kinetics; Mammals; Mixed Function Oxygenases; Molecular Sequence Data; NADPH-Ferrihemoprotein Reductase; Oligodeoxyribonucleotides; Repressor Proteins; Transcription Factors | 1996 |
Phototoxicity of non-steroidal anti-inflammatory drugs: in vitro studies with visible light.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Dermatitis, Phototoxic; Diclofenac; Erythrocytes; Hemolysis; Humans; Ibuprofen; In Vitro Techniques; Ketoprofen; Light; Naproxen; Phenylbutazone; Photosensitizing Agents; Piroxicam; Propionates | 1996 |
Effect of the enantiomers of flurbiprofen, ibuprofen, and ketoprofen on intestinal permeability.
Topics: Animals; Dose-Response Relationship, Drug; Flurbiprofen; Ibuprofen; Intestinal Absorption; Ketoprofen; Male; Rats; Rats, Sprague-Dawley; Stereoisomerism | 1996 |
Comparative mutagenic and genotoxic effects of three propionic acid derivatives ibuprofen, ketoprofen and naproxen.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Marrow Cells; Ibuprofen; In Vitro Techniques; Ketoprofen; Male; Mice; Microsomes, Liver; Mutagenicity Tests; Mutagens; Naproxen; Rats; Salmonella typhimurium; Sister Chromatid Exchange | 1997 |
Measurement of plasma ibuprofen by gas chromatography-mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Cystic Fibrosis; Drug Monitoring; Fenoprofen; Gas Chromatography-Mass Spectrometry; Humans; Ibuprofen; Ketoprofen; Naproxen; Sensitivity and Specificity | 1997 |
Separation of profen enantiomers by capillary electrophoresis using cyclodextrins as chiral selectors.
Topics: Cyclodextrins; Electrophoresis, Capillary; Fenoprofen; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Methanol; Osmolar Concentration; Phenylpropionates; Stereoisomerism; Temperature; Time Factors | 1998 |
HPLC on Chiralcel OJ-R for enantiomer separation and analysis of ketoprofen, from horse plasma, as the 9-aminophenanthrene derivative.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoates; Biotransformation; Cellulose; Chromatography, High Pressure Liquid; Fluorescent Dyes; Horses; Ibuprofen; Ketoprofen; Male; Phenanthrenes; Stereoisomerism | 1998 |
Prodrugs. Part 3. 2-Formylphenyl esters of indomethacin, ketoprofen and ibuprofen and 6-substituted 2-formyl and 2-acylphenyl esters of aspirin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ibuprofen; Indomethacin; Ketoprofen; Male; Prodrugs; Rats; Rats, Wistar | 1998 |
Gastrointestinal toxicity of over-the-counter analgesics.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Gastric Mucosa; Humans; Ibuprofen; Intestinal Mucosa; Intestines; Ketoprofen; Naproxen; Nonprescription Drugs; Peptic Ulcer; Stomach; Time Factors | 1998 |
Effect of chemical structure on the release of certain propionic acid derivatives from their dosage forms.
Topics: Capsules; Chemical Phenomena; Chemistry, Physical; Dosage Forms; Drug Compounding; Drug Stability; Drug Storage; Flurbiprofen; Humans; Ibuprofen; Ketoprofen; Molecular Structure; Naproxen; Propionates; Suppositories | 1998 |
Chiral discrimination in the transport of ketoprofen and ibuprofen esters through an aqueous phase mediated by various serum albumins.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Hydrogen-Ion Concentration; Ibuprofen; In Vitro Techniques; Ketoprofen; Rats; Serum Albumin; Serum Albumin, Bovine; Solubility; Stereoisomerism; Temperature; Water | 1999 |
[Pharmacology of antipyretics: applications to their use in pediatrics].
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child; Child, Preschool; Humans; Ibuprofen; Ketoprofen | 1999 |
The dissolution and complexing properties of ibuprofen and ketoprofen when mixed with N-methylglucamine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Hot Temperature; Ibuprofen; Ketoprofen; Meglumine; Powders; Solubility; Water; X-Ray Diffraction | 1999 |
Liquid-phase microextraction and capillary electrophoresis of acidic drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Naproxen | 2000 |
Uptake of ibuprofen, indomethacin and ketoprofen into isolated rabbit parietal cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cold Temperature; Hydrogen-Ion Concentration; Ibuprofen; Indomethacin; Ketoprofen; Male; Parietal Cells, Gastric; Rabbits | 2000 |
R- and S-isomers of nonsteroidal anti-inflammatory drugs differentially regulate cytokine production.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Dinoprostone; Female; Flurbiprofen; Ibuprofen; In Vitro Techniques; Interleukin-10; Interleukin-6; Ketoprofen; Lipopolysaccharides; Macrophages, Peritoneal; Mice; RNA, Messenger; Stereoisomerism; Tumor Necrosis Factor-alpha | 2000 |
Determination of some antirheumatics by capillary isotachophoresis.
Topics: Antirheumatic Agents; Electrophoresis, Capillary; Fenoprofen; Humans; Ibuprofen; Ketoprofen; Naproxen | 2000 |
Determination of nonsteroidal anti-inflammatory drugs in biological fluids by automatic on-line integration of solid-phase extraction and capillary electrophoresis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Automation; Chromatography, Micellar Electrokinetic Capillary; Humans; Ibuprofen; Indomethacin; Ketoprofen; Phenylbutyrates; Tolmetin | 2001 |
[Two complex suicidal poisonings with drugs and their medicolegal aspects].
Topics: Adult; Atenolol; Chromatography, High Pressure Liquid; Diclofenac; Estazolam; Fatal Outcome; Female; Humans; Ibuprofen; Illicit Drugs; Ketoprofen; Male; Metronidazole; Naproxen; Poland; Suicide, Attempted; Theophylline; Tolperisone | 2001 |
Binding constant determination of drugs toward subdomain IIIA of human serum albumin by near-infrared dye-displacement capillary electrophoresis.
Topics: Binding, Competitive; Clofibrate; Coloring Agents; Electrophoresis, Capillary; Humans; Ibuprofen; Imipramine; Indoles; Ketoprofen; Kinetics; Naproxen; Protein Binding; Protein Structure, Tertiary; Quinidine; Serum Albumin; Stereoisomerism; Sulfonic Acids | 2001 |
Contribution of nonsteroidal anti-inflammatory drugs to deaths associated with peptic ulcer disease: a prospective toxicological analysis of autopsy blood samples.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cause of Death; Chromatography, High Pressure Liquid; Diclofenac; Female; Humans; Ibuprofen; Intestinal Mucosa; Ketoprofen; Male; Middle Aged; Peptic Ulcer; Prospective Studies; Survival Rate | 2001 |
Kinetics and hydrolysis mechanism of polymeric prodrugs containing ibuprofen, ketoprofen, and naproxen as pendent agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Stability; Edema; Female; Hydrogen-Ion Concentration; Hydrolysis; Ibuprofen; Ketoprofen; Kinetics; Methacrylates; Naproxen; Polymers; Prodrugs; Rats; Rats, Wistar; Solubility; Treatment Outcome | 2002 |
Percutaneous absorption of non-steroidal anti-inflammatory drugs from in situ gelling xyloglucan formulations in rats.
Topics: Administration, Cutaneous; Administration, Topical; Animals; Anti-Inflammatory Agents; Biological Availability; Cellulose; Drug Carriers; Gels; Glucans; Ibuprofen; In Vitro Techniques; Ketoprofen; Male; Membranes; Poloxamer; Polysaccharides; Rats; Rats, Wistar; Skin Absorption; Xylans | 2002 |
Enhancement of selectivity and resolution in the enantioseparation of uncharged compounds using mixtures of oppositely charged cyclodextrins in capillary electrophoresis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclodextrins; Electrophoresis, Capillary; Fenoprofen; Flurbiprofen; Ibuprofen; Ketoprofen; Static Electricity; Stereoisomerism | 2003 |
Modeling of adhesion in tablet compression--I. Atomic force microscopy and molecular simulation.
Topics: Adhesiveness; Chemistry, Pharmaceutical; Compressive Strength; Drug Compounding; Flurbiprofen; Ibuprofen; Iron; Ketoprofen; Microscopy, Atomic Force; Models, Molecular; Surface Properties; Tablets; X-Ray Diffraction | 2003 |
Polarised transport of monocarboxylic acid type drugs across rat jejunum in vitro: the effect of mucolysis and ATP-depletion.
Topics: Adenosine Triphosphate; Animals; Biological Transport, Active; Carboxylic Acids; Cell Membrane Permeability; Cysteine; Gemfibrozil; Hydrogen-Ion Concentration; Ibuprofen; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Jejunum; Ketoprofen; Male; Membranes, Artificial; Rats; Rats, Wistar; Sodium Azide | 2003 |
Effect of polymer hydration on the kinetic release of drugs: a study of ibuprofen and ketoprofen in HPMC matrices.
Topics: Calorimetry, Differential Scanning; Excipients; Humidity; Hypromellose Derivatives; Ibuprofen; Ketoprofen; Kinetics; Methylcellulose; Polymers; Solubility; Temperature; Thermogravimetry; Time Factors; Water | 2003 |
The in vitro delivery of NSAIDs across skin was in proportion to the delivery of essential fatty acids in the vehicle--evidence that solutes permeate skin associated with their solvation cages?
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fish Oils; Ibuprofen; In Vitro Techniques; Ketoprofen; Permeability; Pharmaceutical Vehicles; Skin Absorption; Swine | 2003 |
Simultaneous chiral discrimination of multiple profens by cyclodextrin-modified capillary electrophoresis in normal and reversed polarity modes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclodextrins; Electrophoresis, Capillary; Flurbiprofen; Hexadimethrine Bromide; Ibuprofen; Ketoprofen; Phenylpropionates; Stereoisomerism | 2003 |
Antinociceptive synergy, additivity, and subadditivity with combinations of oral glucosamine plus nonopioid analgesics in mice.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Disease Models, Animal; Drug Therapy, Combination; Glucosamine; Ibuprofen; Indomethacin; Ketoprofen; Mice; Pain; Piroxicam | 2003 |
Complexation trends and binding constants between dextrin oligomers and small molecules as measured through affinity capillary electrophoresis.
Topics: Analgesics; Carbohydrate Sequence; Dextrins; Electrophoresis, Capillary; Fluorescent Dyes; Glucans; Ibuprofen; Ketoprofen; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Naproxen; Oligosaccharides; Protein Binding; Pyrenes; Staining and Labeling | 2003 |
Modeling of adhesion in tablet compression. II. Compaction studies using a compaction simulator and an instrumented tablet press.
Topics: Adhesiveness; Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Drug Compounding; Flurbiprofen; Ibuprofen; Ketoprofen; Lubrication; Pressure; Surface Properties; Tablets | 2004 |
Acute renal failure after treatment with non-steroidal anti-inflammatory drugs.
Topics: Acute Kidney Injury; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Causality; Child; Child, Preschool; Female; Humans; Hypovolemia; Ibuprofen; Ketoprofen; Male; Renal Plasma Flow | 2004 |
Investigation of the release test method for the topical application of pharmaceutical preparations: release test of cataplasm including nonsteroidal anti-inflammatory drugs using artificial sweat.
Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Flurbiprofen; Humans; Ibuprofen; Ketoprofen; Kinetics; Solubility; Sweat; Tablets | 2004 |
Application of capillary electrophoresis with different sample stacking strategies for the determination of a group of nonsteroidal anti-inflammatory drugs in the low microg x L(-1) concentration range.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Electrophoresis, Capillary; Fenoprofen; Ibuprofen; Ketoprofen; Naproxen; Water | 2004 |
Synthesis, biological activity and molecular modeling studies of novel COX-1 inhibitors.
Topics: Adsorption; Benzoates; Binding Sites; Biological Availability; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Design; Enzyme Activation; Ethane; Ibuprofen; Isoenzymes; Ketoprofen; Ligands; Models, Molecular; Molecular Conformation; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship | 2004 |
Nonsteroidal anti-inflammatory drug-induced liver injury: a case-control study in primary care.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Cholestasis; Diclofenac; Drug Therapy, Combination; Female; Flurbiprofen; Hepatocytes; Humans; Ibuprofen; Ketoprofen; Liver; Male; Meloxicam; Middle Aged; Niflumic Acid; Primary Health Care; Salicylates; Sex Distribution; Statistics, Nonparametric; Thiazines; Thiazoles; Time Factors | 2004 |
Tracking acidic pharmaceuticals, caffeine, and triclosan through the wastewater treatment process.
Topics: Caffeine; Diclofenac; Ibuprofen; Ketoprofen; Meclofenamic Acid; Models, Chemical; Naproxen; Pharmaceutical Preparations; Triclosan; Waste Disposal, Fluid; Water Pollutants, Chemical | 2005 |
Occurrence of several acidic drugs in sewage treatment plants in Switzerland and risk assessment.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Clofibric Acid; Diclofenac; Environmental Monitoring; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Mefenamic Acid; No-Observed-Adverse-Effect Level; Risk Assessment; Sewage; Switzerland; Waste Disposal, Fluid; Water Pollutants, Chemical | 2005 |
Occurrence of acidic pharmaceuticals in raw and treated sewages and in receiving waters.
Topics: Bezafibrate; Diclofenac; Environmental Pollutants; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Molecular Structure; Naproxen; Sewage; Water | 2005 |
Optimization of gas chromatographic method for the enantioseparation of arylpropionic non-steroidal anti-inflammatory drug methyl esters.
Topics: Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Catalysis; Chemistry, Pharmaceutical; Chromatography; Chromatography, Gas; Cyclodextrins; Drug Industry; Esters; Fenoprofen; Ibuprofen; Ketoprofen; Pressure; Stereoisomerism; Temperature | 2005 |
Pathways and metabolites of microbial degradation of selected acidic pharmaceutical and their occurrence in municipal wastewater treated by a membrane bioreactor.
Topics: Aerobiosis; Amides; Bezafibrate; Biodegradation, Environmental; Bioreactors; Cities; Diclofenac; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Sewage; Spectrometry, Mass, Electrospray Ionization; Time Factors; Waste Disposal, Fluid; Water Pollutants, Chemical | 2005 |
Photodegradation of common environmental pharmaceuticals and estrogens in river water.
Topics: Chromatography, High Pressure Liquid; Environmental Monitoring; Estrogens; Gemfibrozil; Half-Life; Ibuprofen; Ketoprofen; Naproxen; Oxygen; Pharmaceutical Preparations; Photolysis; Propranolol; Rivers; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Water Pollutants, Chemical | 2005 |
The novel formulation design of self-emulsifying drug delivery systems (SEDDS) type O/W microemulsion I: enhancing effects on oral bioavailability of poorly water soluble compounds in rats and beagle dogs.
Topics: Animals; Area Under Curve; Benzofurans; Biological Availability; Dogs; Drug Delivery Systems; Drug Design; Emulsions; Gastric Mucosa; Ibuprofen; Indoles; Ketoprofen; Lipids; Male; Particle Size; Rats; Rats, Sprague-Dawley; Solubility; Surface-Active Agents | 2005 |
Comparative assessment of two indices of drug induced permeability changes in the perfused rat intestine.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Glycine; Ibuprofen; In Vitro Techniques; Intestinal Mucosa; Intestines; Ketoprofen; Naproxen; Permeability; Phenylalanine; Polyethylene Glycols; Rats | 2006 |
Fluidity and tableting characteristics of a powder solid dispersion of the low melting drugs ketoprofen and ibuprofen with crospovidone.
Topics: Cellulose; Chemistry, Pharmaceutical; Drug Compounding; Drug Stability; Excipients; Ibuprofen; Ketoprofen; Povidone; Powders; Solubility; Tablets; Transition Temperature; X-Ray Diffraction | 2006 |
Chondroitin sulfate-based anti-inflammatory macromolecular prodrugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Carrageenan; Chemical Phenomena; Chemistry, Physical; Chondroitin ABC Lyase; Chondroitin Sulfates; Edema; Excipients; Hydrolysis; Ibuprofen; Ketoprofen; Magnetic Resonance Spectroscopy; Male; Naproxen; Polyethylene Glycols; Prodrugs; Rats; Rats, Wistar; Solubility; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared | 2006 |
Design of original bioactive formulations based on sugar-surfactant/non-steroidal anti-inflammatory catanionic self-assemblies: a new way of dermal drug delivery.
Topics: Administration, Topical; Animals; Anions; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cations; Drug Carriers; Drug Delivery Systems; Drug Design; Ear; Edema; Ibuprofen; Indomethacin; Ketoprofen; Male; Mice; Permeability; Pharmaceutical Preparations; Skin Absorption; Surface-Active Agents; Swine | 2007 |
Micellar solubilization of selected non-steroidal therapeutic agents by new surface-active agents of the class of the products of oxyethylation of ursodeoxycholic acid.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Ketoprofen; Micelles; Naproxen; Pharmaceutical Preparations; Solubility; Solutions; Surface-Active Agents; Ursodeoxycholic Acid; Viscosity | 2006 |
Antipyretic drug use in children in French office based medical practice.
Topics: Acetaminophen; Age Factors; Analgesics, Non-Narcotic; Aspirin; Child; Child, Preschool; Drug Therapy, Combination; Fever; France; Humans; Ibuprofen; Infant; Infant, Newborn; Ketoprofen; Physicians' Offices; Practice Guidelines as Topic; Practice Patterns, Physicians' | 2007 |
Elimination of selected acidic pharmaceuticals from municipal wastewater by an activated sludge system and membrane bioreactors.
Topics: Bioreactors; Diclofenac; Ibuprofen; Ketoprofen; Membranes, Artificial; Molecular Weight; Pharmaceutical Preparations; Sewage; Water Purification | 2007 |
Combining anticholinergic and anti-inflammatory activities into a single moiety: a novel approach to reduce gastrointestinal toxicity of ibuprofen and ketoprofen.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholinergic Antagonists; Drug Design; Esters; Female; Gastrointestinal Tract; Humans; Ibuprofen; Ketoprofen; Male; Models, Animal; Peptic Ulcer; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2007 |
Equilibrium solubilization of lipophilic therapeutic agents by aqueous solutions of products of catalytic oxyethylation of Croda-type lanolin as model excipients of the class of non-ionic surface active agents.
Topics: Administration, Cutaneous; Algorithms; Catalysis; Chemistry, Pharmaceutical; Ethylenes; Excipients; Ibuprofen; Ketoprofen; Lanolin; Models, Chemical; Naproxen; Pharmaceutical Vehicles; Solubility; Solutions; Structure-Activity Relationship; Surface-Active Agents; Thermodynamics; Viscosity; Water | 2007 |
Cyclodextrin controlled release of poorly water-soluble drugs from hydrogels.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Anti-Inflammatory Agents; beta-Cyclodextrins; Chemistry, Pharmaceutical; Cross-Linking Reagents; Delayed-Action Preparations; Diffusion; Drug Carriers; Drug Compounding; gamma-Cyclodextrins; Hydrogels; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Kinetics; Methacrylates; Models, Chemical; Particle Size; Polyethylene Glycols; Povidone; Prednisolone; Solubility; Water | 2008 |
Design, synthesis and in vitro evaluation of vinyl ether type polymeric prodrugs of ibuprofen, ketoprofen and naproxen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Hydrogen-Ion Concentration; Hydrolysis; Ibuprofen; Ketoprofen; Magnetic Resonance Spectroscopy; Naproxen; Polymers; Prodrugs; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Vinyl Compounds | 2008 |
Identification of the carboxylic acid functionality by using electrospray ionization and ion-molecule reactions in a modified linear quadrupole ion trap mass spectrometer.
Topics: Acetates; Anti-Inflammatory Agents, Non-Steroidal; Borates; Carboxylic Acids; Cations, Monovalent; Ibuprofen; Ketoprofen; Methanol; Naproxen; Sodium; Spectrometry, Mass, Electrospray Ionization | 2008 |
Characterization of drug-protein binding process by employing equilibrium sampling through hollow-fiber supported liquid membrane and Bjerrum and Scatchard plots.
Topics: Amides; Anesthetics, Local; Anti-Anxiety Agents; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Binding Sites; Binding, Competitive; Blood Proteins; Fluvoxamine; Glycoproteins; Humans; Ibuprofen; Ketoprofen; Kinetics; Membranes, Artificial; Pharmaceutical Preparations; Protein Binding; Proteins; Ropivacaine; Serum Albumin; Stereoisomerism | 2008 |
Solubilizing and lithogenolitic properties of water solutions of non-ionic surfactants of cholesterol oxyethylenation products.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Catalysis; Cholesterol; Ethylene Oxide; Ibuprofen; Ions; Ketoprofen; Lithiasis; Micelles; Models, Theoretical; Naproxen; Solubility; Solutions; Surface-Active Agents; Water | 2007 |
Identification and quantification of ibuprofen, naproxen, ketoprofen and diclofenac present in waste-waters, as their trimethylsilyl derivatives, by gas chromatography mass spectrometry.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Gas Chromatography-Mass Spectrometry; Hungary; Ibuprofen; Ketoprofen; Naproxen; Trimethylsilyl Compounds; Waste Disposal, Fluid; Water Pollutants, Chemical | 2008 |
Prescriptions of NSAIDs to patients undergoing third molar surgery : an observational, prospective, multicentre survey.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Dental Health Surveys; Diclofenac; Drug Prescriptions; Female; Humans; Hungary; Ibuprofen; Italy; Ketoprofen; Male; Molar, Third; Pain Measurement; Pain, Postoperative; Prospective Studies; Sulfonamides; Treatment Outcome | 2008 |
Removal of selected pharmaceuticals by chlorination, coagulation-sedimentation and powdered activated carbon treatment.
Topics: Antipyrine; Charcoal; Clofibric Acid; Diclofenac; Fenoprofen; Gemfibrozil; Halogenation; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Water Pollutants, Chemical; Water Purification; Water Supply | 2008 |
Effect of chirality on PVP/drug interaction within binary physical mixtures of ibuprofen, ketoprofen, and naproxen: a DSC study.
Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Hot Temperature; Ibuprofen; Ketoprofen; Molecular Structure; Naproxen; Povidone; Stereoisomerism | 2009 |
Purification of high-throughput organic synthesis libraries by counter-current chromatography.
Topics: Acylation; Chromatography, High Pressure Liquid; Countercurrent Distribution; Dimethyl Sulfoxide; Equipment Design; Ibuprofen; Ketoprofen; Methanol; Organic Chemicals; Small Molecule Libraries; Solubility; Solvents | 2009 |
Importance of surface properties of affinity resin for capturing a target protein, cyclooxygenase-1.
Topics: Animals; Aspirin; Chromatography, Affinity; Cyclooxygenase 1; Ibuprofen; Ketoprofen; Ligands; Protein Binding; Proteins; Rats; Resins, Synthetic; Surface Properties | 2009 |
Determination of widely used non-steroidal anti-inflammatory drugs in water samples by in situ derivatization, continuous hollow fiber liquid-phase microextraction and gas chromatography-flame ionization detector.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Gas; Drug Residues; Flame Ionization; Ibuprofen; Ketoprofen; Naproxen; Reproducibility of Results; Water Pollutants, Chemical | 2009 |
Differences in the interaction between aryl propionic acid derivatives and poly(vinylpyrrolidone) K30: A multi-methodological approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Carbon Isotopes; Crystallization; Drug Stability; Flurbiprofen; Hot Temperature; Humidity; Hydrogen Bonding; Ibuprofen; Ketoprofen; Magnetic Resonance Spectroscopy; Molecular Structure; Molecular Weight; Naproxen; Phase Transition; Phenylbutyrates; Polymers; Povidone; Static Electricity; X-Ray Diffraction | 2009 |
Determination of ibuprofen, ketoprofen, diclofenac and phenylbutazone in bovine milk by gas chromatography-tandem mass spectrometry.
Topics: Animals; Cattle; Diclofenac; Drug Residues; Food Analysis; Food Contamination; Gas Chromatography-Mass Spectrometry; Ibuprofen; Ketoprofen; Milk; Phenylbutazone; Sensitivity and Specificity; Tandem Mass Spectrometry | 2008 |
Stochiometrically governed molecular interactions in drug: poloxamer solid dispersions.
Topics: Crystallization; Differential Thermal Analysis; Drug Carriers; Drug Compounding; Hydrogen Bonding; Ibuprofen; Ketoprofen; Phase Transition; Poloxamer; Solubility | 2010 |
Physicochemical studies of binary eutectic of ibuprofen and ketoprofen for enhanced transdermal drug delivery.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Chemical Phenomena; Drug Combinations; Drug Delivery Systems; Ibuprofen; Ketoprofen; Permeability; Skin; Skin Absorption; Snakes; Solubility; Thermodynamics | 2010 |
Second interlaboratory exercise on non-steroidal anti-inflammatory drug analysis in environmental aqueous samples.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemistry Techniques, Analytical; Diclofenac; Environmental Monitoring; Filtration; Gas Chromatography-Mass Spectrometry; Ibuprofen; Ketoprofen; Naproxen; Reproducibility of Results; Water Pollutants, Chemical; Water Purification | 2010 |
Influence of ionic strength, anions, cations, and natural organic matter on the adsorption of pharmaceuticals to silica.
Topics: Adsorption; Anions; Carbamazepine; Cations; Diclofenac; Ibuprofen; Ketoprofen; Osmolar Concentration; Pharmaceutical Preparations; Silicon Dioxide; Soil | 2010 |
The role of the acquisition methods in the analysis of the non-steroidal anti-inflammatory drugs in Danube River by gas chromatography-mass spectrometry.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Gas Chromatography-Mass Spectrometry; Ibuprofen; Ketoprofen; Limit of Detection; Naproxen; Rivers; Water Pollutants, Chemical | 2010 |
Determination of non-steroidal anti-inflammatory drugs in sewage sludge by direct hollow fiber supported liquid membrane extraction and liquid chromatography-mass spectrometry.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Fractionation; Chromatography, Liquid; Diclofenac; Ibuprofen; Ketoprofen; Mass Spectrometry; Naproxen; Reproducibility of Results; Sewage | 2010 |
Interaction between dexibuprofen and dexketoprofen in the orofacial formalin test in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Drug Interactions; Face; Ibuprofen; Ketoprofen; Male; Mice; Mouth; Pain Measurement; Stereoisomerism | 2011 |
Phototransformation of ibuprofen and ketoprofen in aqueous solutions.
Topics: Chromatography, High Pressure Liquid; Environmental Restoration and Remediation; Gas Chromatography-Mass Spectrometry; Ibuprofen; Ketoprofen; Kinetics; Mass Spectrometry; Oxygen; Photolysis; Ultraviolet Rays; Water; Water Pollutants, Chemical | 2011 |
Enantioselective analysis of ibuprofen, ketoprofen and naproxen in wastewater and environmental water samples.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Gas Chromatography-Mass Spectrometry; Ibuprofen; Ketoprofen; Linear Models; Naproxen; Reproducibility of Results; Sewage; Solid Phase Extraction; Stereoisomerism; Tandem Mass Spectrometry; Waste Disposal, Fluid; Water Pollutants, Chemical | 2011 |
Enantiospecific fate of ibuprofen, ketoprofen and naproxen in a laboratory-scale membrane bioreactor.
Topics: Bioreactors; Ibuprofen; Ketoprofen; Laboratories; Membranes, Artificial; Naproxen; Reference Standards; Stereoisomerism; Tandem Mass Spectrometry; Waste Disposal, Fluid | 2011 |
Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; ATP-Binding Cassette Transporters; Biological Transport, Active; Cytochrome P-450 Enzyme System; Diclofenac; Electron Transport; Genes, MDR; Ibuprofen; Indomethacin; Ketoprofen; Ketorolac; Mitochondria; Naproxen; Reactive Oxygen Species; Sulindac; Tolmetin; Yeasts | 2012 |
Biofilm controlled sorption of selected acidic drugs on river sediments characterized by different organic carbon content.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biofilms; Carbon; Diclofenac; Gas Chromatography-Mass Spectrometry; Geologic Sediments; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Naproxen; Rivers; Water Pollutants, Chemical | 2012 |
Batch versus continuous feeding strategies for pharmaceutical removal by subsurface flow constructed wetland.
Topics: Biodegradation, Environmental; Caffeine; Carbamazepine; Clofibric Acid; Diclofenac; Ibuprofen; Ketoprofen; Kinetics; Pharmaceutical Preparations; Waste Disposal, Fluid; Water Movements; Water Pollutants, Chemical; Wetlands | 2012 |
Acidic pharmaceuticals in domestic wastewater and receiving water from hyper-urbanization city of China (Shanghai): environmental release and ecological risk.
Topics: China; Cities; Diclofenac; Environmental Monitoring; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Risk Assessment; Urbanization; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Water Pollution, Chemical | 2013 |
Arginine 485 of human serum albumin interacts with the benzophenone moiety of ketoprofen in the binding pocket of subdomain III A and III B.
Topics: Affinity Labels; Amino Acid Sequence; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Autoradiography; Benzophenones; Binding Sites; Chromatography, High Pressure Liquid; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Humans; Ibuprofen; Ketoprofen; Ligands; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Mutation; Photochemistry; Pichia; Protein Conformation; Recombinant Proteins; Serum Albumin | 2012 |
Development of poly(glycerol adipate) nanoparticles loaded with non-steroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Carriers; Ibuprofen; Ketoprofen; Nanoparticles; Polyesters | 2012 |
In silico prediction of drug dissolution and absorption with variation in intestinal pH for BCS class II weak acid drugs: ibuprofen and ketoprofen.
Topics: Absorption; Biopharmaceutics; Computer Simulation; Humans; Hydrogen-Ion Concentration; Ibuprofen; Intestinal Mucosa; Ketoprofen; Models, Biological; Mouth Mucosa; Predictive Value of Tests; Solubility; Tablets; Therapeutic Equivalency | 2012 |
The role of microbial adaptation and biodegradable dissolved organic carbon on the attenuation of trace organic chemicals during groundwater recharge.
Topics: 2-Methyl-4-chlorophenoxyacetic Acid; 2,4-Dichlorophenoxyacetic Acid; Adaptation, Physiological; Biodegradation, Environmental; Carbon; Clofibric Acid; Gemfibrozil; Groundwater; Ibuprofen; Ketoprofen; Naproxen; Organic Chemicals; Soil Microbiology; Water Microbiology; Water Pollutants, Chemical; Water Purification | 2012 |
Microneedle pretreatment enhances the percutaneous permeation of hydrophilic compounds with high melting points.
Topics: Acetaminophen; Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Diclofenac; Female; Hydrophobic and Hydrophilic Interactions; Ibuprofen; In Vitro Techniques; Ketoprofen; Needles; Skin Absorption; Transition Temperature | 2012 |
Multi-phase partitioning, ecological risk and fate of acidic pharmaceuticals in a wastewater receiving river: the role of colloids.
Topics: Aquatic Organisms; Clofibric Acid; Colloids; Diclofenac; Ecotoxicology; Geologic Sediments; Ibuprofen; Ketoprofen; Models, Theoretical; Naproxen; Pharmaceutical Preparations; Risk Assessment; Rivers; Wastewater; Water Pollutants, Chemical | 2013 |
Modelling the biodegradation of non-steroidal anti-inflammatory drugs (NSAIDs) by activated sludge and a pure culture.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bacteria; Biodegradation, Environmental; Computer Simulation; Ibuprofen; Ketoprofen; Kinetics; Models, Biological; Phylogeny; Portugal; Sewage | 2013 |
Solubility enhancement of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) using polypolypropylene oxide core PAMAM dendrimers.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Dendrimers; Diflunisal; Drug Delivery Systems; Ibuprofen; Ketoprofen; Polymers; Propylene Glycols; Solubility; Temperature | 2013 |
[Occurrence and risk assessment of five selected PPCPs in municipal wastewater treatment plant and the receiving water].
Topics: China; Cities; Clofibric Acid; Diclofenac; Environmental Monitoring; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Risk Assessment; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2013 |
Sensing chiral drugs by using CdSe/ZnS nanoparticles capped with N-acetyl-L-cysteine methyl ester.
Topics: Acetylcysteine; Cadmium Compounds; Circular Dichroism; Esters; Flurbiprofen; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Quantum Dots; Selenium Compounds; Spectrometry, Fluorescence; Stereoisomerism; Sulfides; Zinc Compounds | 2013 |
Non-steroidal anti-inflammatory drugs in Indian rivers.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Humans; Ibuprofen; India; Ketoprofen; Naproxen; Rivers; Sewage; Solid Phase Extraction; Water Pollutants, Chemical | 2014 |
Removal of non-steroidal anti-inflammatory drugs ibuprofen and ketoprofen from water by emulsion liquid membrane.
Topics: Carbonates; Emulsions; Hexanes; Hexoses; Ibuprofen; Ketoprofen; Membranes, Artificial; Sodium Chloride; Solutions; Sulfuric Acids; Surface-Active Agents; Water Purification | 2014 |
Evaluation of drug delivery to intact and porated skin by coherent Raman scattering and fluorescence microscopies.
Topics: Ablation Techniques; Animals; Crystallization; Dermatologic Surgical Procedures; Drug Delivery Systems; Hot Temperature; Ibuprofen; In Vitro Techniques; Ketoprofen; Mice; Microscopy, Fluorescence; Nanoparticles; Porosity; Propylene Glycol; Skin; Spectrum Analysis, Raman; Swine | 2014 |
High-performance liquid chromatographic enantioseparation of racemic drugs based on homochiral metal-organic framework.
Topics: Benzoin; Benzyl Alcohols; Chromatography, High Pressure Liquid; Coordination Complexes; Ethylenediamines; Ibuprofen; Ketoprofen; Naproxen; Porosity; Pyridines; Stereoisomerism; Zinc | 2014 |
Elucidation of transformation pathway of ketoprofen, ibuprofen, and furosemide in surface water and their occurrence in the aqueous environment using UHPLC-QTOF-MS.
Topics: Chromatography, Liquid; Ecotoxicology; Environment; Environmental Monitoring; Furosemide; Ibuprofen; Ketoprofen; Kinetics; Mass Spectrometry; Photochemistry; Photolysis; Rivers; Wastewater; Water Pollutants, Chemical; Water Purification; Xenon | 2014 |
[Simultaneous determination of nine pharmaceuticals personal care products in waters by solid phase extraction-gas chromatography-mass spectrometry].
Topics: Acetaminophen; Agricultural Irrigation; Benzhydryl Compounds; Clofibric Acid; Diclofenac; Gas Chromatography-Mass Spectrometry; Ibuprofen; Ketoprofen; Naproxen; Phenols; Salicylic Acid; Solid Phase Extraction; Triclosan; Water; Water Pollutants, Chemical | 2014 |
Co-metabolic oxidation of pharmaceutical compounds by a nitrifying bacterial enrichment.
Topics: Ammonium Compounds; Bacteria; Biodegradation, Environmental; Biotransformation; Cell Membrane; Diffusion; Ibuprofen; Ketoprofen; Kinetics; Nitrification; Oxidation-Reduction; Pharmaceutical Preparations | 2014 |
Fast ibuprofen, ketoprofen and naproxen simultaneous determination in human serum for clinical toxicology by GC-FID.
Topics: Chromatography, Gas; Humans; Ibuprofen; Ketoprofen; Naproxen | 2014 |
In vivo predictive dissolution: transport analysis of the CO2 , bicarbonate in vivo buffer system.
Topics: Bicarbonates; Buffers; Carbon Dioxide; Chemistry, Pharmaceutical; Diffusion; Equipment Design; Hydrogen-Ion Concentration; Ibuprofen; Indomethacin; Ketoprofen; Kinetics; Models, Chemical; Solubility; Technology, Pharmaceutical | 2014 |
Determination of thermodynamic values of acidic dissociation constants and complexation constants of profens and their utilization for optimization of separation conditions by Simul 5 Complex.
Topics: Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Computer Simulation; Electrophoresis, Capillary; Flurbiprofen; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Magnetic Resonance Spectroscopy; Naproxen; Osmolar Concentration; Software; Thermodynamics; Viscosity | 2014 |
Occurrence of selected pharmaceuticals in the principal sewage treatment plants in Rome (Italy) and in the receiving surface waters.
Topics: Carbamazepine; Chromatography, Liquid; Diclofenac; Environmental Monitoring; Estrone; Gemfibrozil; Humans; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Risk Assessment; Rivers; Rome; Seasons; Solid Phase Extraction; Tandem Mass Spectrometry; Waste Disposal, Fluid; Water Pollutants, Chemical | 2015 |
Ion-exchange selectivity of diclofenac, ibuprofen, ketoprofen, and naproxen in ureolyzed human urine.
Topics: Acetaminophen; Anion Exchange Resins; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Diclofenac; Humans; Hydrogen Bonding; Ibuprofen; Ion Exchange; Ketoprofen; Kinetics; Molecular Structure; Naproxen; Static Electricity; Urea; Waste Disposal, Fluid; Water Pollutants, Chemical | 2015 |
Enantioselective determination of representative profens in wastewater by a single-step sample treatment and chiral liquid chromatography-tandem mass spectrometry.
Topics: Chromatography, Liquid; Ibuprofen; Ketoprofen; Limit of Detection; Naproxen; Stereoisomerism; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical | 2015 |
Ionic liquids for improving the extraction of NSAIDs in water samples using dispersive liquid-liquid microextraction by high performance liquid chromatography-diode array-fluorescence detection.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Diclofenac; Fluorescence; Ibuprofen; Imidazoles; Ionic Liquids; Ketoprofen; Liquid Phase Microextraction; Water Pollutants, Chemical | 2015 |
Parallel artificial liquid membrane extraction of acidic drugs from human plasma.
Topics: Calibration; Chromatography, High Pressure Liquid; Diclofenac; Equipment Design; Flurbiprofen; Gemfibrozil; Humans; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Liquid-Liquid Extraction; Membranes, Artificial; Pharmaceutical Preparations; Polypropylenes; Polyvinyls | 2015 |
Sensing of enantiomeric excess in chiral carboxylic acids.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Carboxylic Acids; Crystallography, X-Ray; Fluorescence; Fluorescent Dyes; Ibuprofen; Ketoprofen; Models, Molecular; Molecular Structure; Naproxen; Stereoisomerism | 2015 |
Dendrimer-functionalized mesoporous silica as a reversed-phase/anion-exchange mixed-mode sorbent for solid phase extraction of acid drugs in human urine.
Topics: Adsorption; Chromatography, High Pressure Liquid; Dendrimers; Female; Humans; Ibuprofen; Ion Exchange; Ketoprofen; Naproxen; Pharmaceutical Preparations; Porosity; Silicon Dioxide; Solid Phase Extraction; Solvents; Spectroscopy, Fourier Transform Infrared | 2015 |
A novel two-dimensional liquid chromatographic system for the online toxicity prediction of pharmaceuticals and related substances.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Chlorophyta; Chromatography, Liquid; Computer Simulation; Daphnia; Diclofenac; Drug Contamination; Drug-Related Side Effects and Adverse Reactions; Fishes; Ibuprofen; Ketoprofen; Lethal Dose 50; Models, Biological; Pharmaceutical Preparations; Photolysis | 2015 |
Fabrication of aluminum terephthalate metal-organic framework incorporated polymer monolith for the microextraction of non-steroidal anti-inflammatory drugs in water and urine samples.
Topics: Adsorption; Aluminum; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Ibuprofen; Ketoprofen; Limit of Detection; Methacrylates; Phenylbutyrates; Phthalic Acids; Salts; Solid Phase Extraction; Water | 2015 |
The Slow Molecular Mobility in Amorphous Ketoprofen and Ibuprofen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Ibuprofen; Ketoprofen; Molecular Dynamics Simulation; Phase Transition; Temperature | 2015 |
Exploring the copper(II)-aminotriazole complex-binding sites of human serum albumin.
Topics: Amitrole; Binding Sites; Binding, Competitive; Circular Dichroism; Coordination Complexes; Copper; Humans; Ibuprofen; Ketoprofen; Molecular Docking Simulation; Serum Albumin; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared | 2015 |
Novel binuclear μ-oxo diruthenium complexes combined with ibuprofen and ketoprofen: Interaction with relevant target biomolecules and anti-allergic potential.
Topics: Animals; Anti-Allergic Agents; beta-N-Acetylhexosaminidases; Cell Degranulation; Cell Line, Tumor; Coordination Complexes; Cytochrome P-450 Enzyme System; Ibuprofen; Immunoglobulin E; Ketoprofen; Male; Mast Cells; Microsomes, Liver; Rats; Rats, Wistar; Ruthenium; Spectrometry, Mass, Electrospray Ionization | 2015 |
A comparative study of ibuprofen and ketoprofen glass-forming liquids by molecular dynamics simulations.
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Dimerization; Glass; Hydrogen Bonding; Ibuprofen; Ketoprofen; Molecular Dynamics Simulation | 2015 |
Single-drop microextraction combined in-line with capillary electrophoresis for the determination of nonsteroidal anti-inflammatory drugs in urine samples.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Electrophoresis, Capillary; Equipment Design; Humans; Ibuprofen; Ketoprofen; Limit of Detection; Liquid Phase Microextraction; Naproxen; Urinalysis | 2016 |
Cysteine amide adduct formation from carboxylic acid drugs via UGT-mediated bioactivation in human liver microsomes.
Topics: Amides; Anti-Inflammatory Agents, Non-Steroidal; Carboxylic Acids; Chromatography, High Pressure Liquid; Cysteine; Diclofenac; Glucuronosyltransferase; Humans; Ibuprofen; In Vitro Techniques; Ketoprofen; Microsomes, Liver; Spectrometry, Mass, Electrospray Ionization | 2015 |
Graphene oxide-based dispersive solid-phase extraction combined with in situ derivatization and gas chromatography-mass spectrometry for the determination of acidic pharmaceuticals in water.
Topics: Diclofenac; Gas Chromatography-Mass Spectrometry; Graphite; Ibuprofen; Ketoprofen; Naproxen; Osmolar Concentration; Pharmaceutical Preparations; Solid Phase Extraction; Solvents; Water; Water Pollutants, Chemical | 2015 |
Ionisation effects on the permeation of pharmaceutical compounds through silicone membrane.
Topics: Benzoic Acid; Chemistry, Pharmaceutical; Chromatography, Gas; Hydrogen-Ion Concentration; Ibuprofen; Ions; Ketoprofen; Lidocaine; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Silicon; Surface Properties; Triazoles | 2016 |
Risk of acute and serious liver injury associated to nimesulide and other NSAIDs: data from drug-induced liver injury case-control study in Italy.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Humans; Ibuprofen; Italy; Ketoprofen; Male; Middle Aged; Multivariate Analysis; Risk; Sulfonamides | 2016 |
Selective non-antibiotic treatment in sigmoid diverticulitis: is it time to change the traditional approach?
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Diverticulitis, Colonic; Drug Therapy, Combination; Female; Humans; Ibuprofen; Ketoprofen; Male; Middle Aged; Patient Selection; Sigmoid Diseases; Tromethamine | 2016 |
Hybrid Compounds Strategy in the Synthesis of Oleanolic Acid Skeleton-NSAID Derivatives.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Humans; Ibuprofen; Inflammation; Ketoprofen; Molecular Structure; Naproxen; Oleanolic Acid | 2016 |
Suitability of passive sampling for the monitoring of pharmaceuticals in Finnish surface waters.
Topics: Calibration; Carbamazepine; Chromatography, Liquid; Diclofenac; Environmental Monitoring; Finland; Ibuprofen; Ketoprofen; Lakes; Naproxen; Pharmaceutical Preparations; Rivers; Seasons; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical | 2016 |
Continuous treatment of non-sterile hospital wastewater by Trametes versicolor: How to increase fungal viability by means of operational strategies and pretreatments.
Topics: Biomass; Bioreactors; Hospitals; Ibuprofen; Ketoprofen; Laccase; Medical Waste; Medical Waste Disposal; Trametes; Ultraviolet Rays; Waste Disposal, Fluid; Water Microbiology; Water Pollutants, Chemical | 2016 |
Fabrication of non-dissolving analgesic suppositories using 3D printed moulds.
Topics: Analgesics; Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diclofenac; Drug Liberation; Elastic Modulus; Ibuprofen; Ketoprofen; Lidocaine; Mice; Printing, Three-Dimensional; Silicone Elastomers; Solubility; Suppositories; Tensile Strength | 2016 |
Non-steroidal anti-inflammatory drugs in the watercourses of Elbe basin in Czech Republic.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Czech Republic; Diclofenac; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Rivers; Water Pollutants, Chemical | 2017 |
High-Quality Metal-Organic Framework ZIF-8 Membrane Supported on Electrodeposited ZnO/2-methylimidazole Nanocomposite: Efficient Adsorbent for the Enrichment of Acidic Drugs.
Topics: Adsorption; Aspirin; Electroplating; Healthy Volunteers; Humans; Ibuprofen; Imidazoles; Ketoprofen; Metal-Organic Frameworks; Nanocomposites; Zeolites; Zinc Oxide | 2017 |
Sorption and desorption of selected non-steroidal anti-inflammatory drugs in an agricultural loam-textured soil.
Topics: Adsorption; Agriculture; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Ketoprofen; Naproxen; Soil; Soil Pollutants | 2017 |
Differential protein modulation by ketoprofen and ibuprofen underlines different cellular response by gastric epithelium.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arginine; Cell Survival; Cytoprotection; Drug Combinations; Epithelial Cells; Ethanol; Gastric Mucosa; Gene Expression Profiling; Gene Regulatory Networks; Humans; Ibuprofen; Ketoprofen; Lysine; MCF-7 Cells; Oligonucleotide Array Sequence Analysis; Real-Time Polymerase Chain Reaction; Time Factors; Transcriptome | 2018 |
Ibuprofen and ketoprofen potentiate UVA-induced cell death by a photosensitization process.
Topics: Apoptosis; Cell Death; Cell Line, Tumor; Cell Survival; Drug Synergism; Humans; Ibuprofen; Ketoprofen; Models, Molecular; Molecular Structure; Photosensitizing Agents; Structure-Activity Relationship; Ultraviolet Rays | 2017 |
Levetiracetam+nonsteroidal anti-inflammatory drug binary systems: A contribution to the development of new solid dosage forms.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Drug Combinations; Drug Liberation; Flurbiprofen; Ibuprofen; Ketoprofen; Levetiracetam; Naproxen; Piracetam; Stereoisomerism | 2017 |
Solid lipid nanoparticles for the controlled delivery of poorly water soluble non-steroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Ibuprofen; Ketoprofen; Lipids; Mice; Nanoparticles; Particle Size; RAW 264.7 Cells; Solubility; Temperature; Water | 2018 |
Preparation of a reversed-phase/anion-exchange mixed-mode spherical sorbent by Pickering emulsion polymerization for highly selective solid-phase extraction of acidic pharmaceuticals from wastewater.
Topics: Butylene Glycols; Emulsions; Environmental Monitoring; Ibuprofen; Ketoprofen; Limit of Detection; Naproxen; Pharmaceutical Preparations; Polymerization; Reproducibility of Results; Solid Phase Extraction; Wastewater; Water Pollutants, Chemical | 2017 |
Continuous transformation of chiral pharmaceuticals in enzymatic membrane bioreactors for advanced wastewater treatment.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bioreactors; Biotransformation; Ibuprofen; Ketoprofen; Membranes, Artificial; Naproxen; Wastewater; Water Pollutants, Chemical | 2017 |
Multifunctionalized mesoporous silica as an efficient reversed-phase/anion exchange mixed-mode sorbent for solid-phase extraction of four acidic nonsteroidal anti-inflammatory drugs in environmental water samples.
Topics: Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Environmental Monitoring; Fresh Water; Ibuprofen; Ketoprofen; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Naproxen; Silanes; Silicon Dioxide; Solid Phase Extraction; Spectroscopy, Fourier Transform Infrared; Wastewater; Water Pollutants, Chemical | 2017 |
Correlation between glucuronidation and covalent adducts formation with proteins of nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Flurbiprofen; Glucuronides; Ibuprofen; Ketoprofen; Male; Microsomes, Liver; Naproxen; Propionates; Protein Binding; Rats, Wistar | 2018 |
Magnetic sporopollenin-cyanopropyltriethoxysilane-dispersive micro-solid phase extraction coupled with high performance liquid chromatography for the determination of selected non-steroidal anti-inflammatory drugs in water samples.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biopolymers; Carotenoids; Chromatography, High Pressure Liquid; Environmental Monitoring; Fresh Water; Ibuprofen; Ketoprofen; Limit of Detection; Magnetics; Solid Phase Microextraction; Wastewater; Water Pollutants, Chemical | 2018 |
Use of Polymer Inclusion Membranes (PIMs) as support for electromembrane extraction of non-steroidal anti-inflammatory drugs and highly polar acidic drugs.
Topics: Amoxicillin; Anti-Inflammatory Agents, Non-Steroidal; Cellulose; Electrochemical Techniques; Hippurates; Ibuprofen; Ketoprofen; Membranes, Artificial; Naproxen; Niacin; ortho-Aminobenzoates; Quaternary Ammonium Compounds; Salicylic Acid | 2018 |
Long-term exposure of Mytilus galloprovincialis to diclofenac, Ibuprofen and Ketoprofen: Insights into bioavailability, biomarkers and transcriptomic changes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Biomarkers; Diclofenac; Ecotoxicology; Ibuprofen; Ketoprofen; Mytilus; Transcriptome; Water Pollutants, Chemical | 2018 |
Dried blood spots and parallel artificial liquid membrane extraction-A simple combination of microsampling and microextraction.
Topics: Amitriptyline; Chromatography, High Pressure Liquid; Dried Blood Spot Testing; Fenoprofen; Flurbiprofen; Healthy Volunteers; Humans; Ibuprofen; Ketoprofen; Liquid-Liquid Extraction; Membranes, Artificial; Quetiapine Fumarate; Tandem Mass Spectrometry | 2018 |
Illicit drugs and pharmaceuticals in swimming pool waters.
Topics: Amphetamines; Carbamazepine; Chromatography, High Pressure Liquid; Cocaine; Environmental Monitoring; Humans; Ibuprofen; Illicit Drugs; Ketoprofen; Pharmaceutical Preparations; Solid Phase Extraction; Swimming Pools; Water Pollutants, Chemical | 2018 |
Chronotherapeutic Drug Delivery of Ketoprofen and Ibuprofen for Improved Treatment of Early Morning Stiffness in Arthritis Using Hot-Melt Extrusion Technology.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Calorimetry, Differential Scanning; Delayed-Action Preparations; Drug Chronotherapy; Drug Compounding; Drug Delivery Systems; Drug Implants; Ibuprofen; Ketoprofen; Solubility; X-Ray Diffraction | 2018 |
Direct chromatographic study of the enantioselective biodegradation of ibuprofen and ketoprofen by an activated sludge.
Topics: Biodegradation, Environmental; Calibration; Chromatography, High Pressure Liquid; Ibuprofen; Ketoprofen; Kinetics; Sewage; Stereoisomerism; Wastewater | 2018 |
Non-steroidal anti-inflammatory drug prescriptions from the 6
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Databases, Factual; Drug Prescriptions; Female; Humans; Ibuprofen; Ketoprofen; Niflumic Acid; Pregnancy | 2019 |
Chitosan tailor-made membranes as biopolymeric support for electromembrane extraction.
Topics: Amoxicillin; Biopolymers; Chitosan; Electrochemical Techniques; Hippurates; Humans; Ibuprofen; Ketoprofen; Naproxen; Niacin; ortho-Aminobenzoates; Salicylic Acid | 2019 |
Switchable-hydrophilicity solvent liquid-liquid microextraction of non-steroidal anti-inflammatory drugs from biological fluids prior to HPLC-DAD determination.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Centrifugation; Chromatography, High Pressure Liquid; Etodolac; Flurbiprofen; Humans; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Ketoprofen; Linear Models; Liquid Phase Microextraction; Milk, Human; Organic Chemicals; Reproducibility of Results; Saliva; Sodium Hydroxide; Solvents | 2019 |
Nitric Oxide and Opioids Involvement in Isobolographic Nsaids Antinociception.
Topics: Acetaminophen; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Ibuprofen; Ketoprofen; Ketorolac; Mice; Nitric Oxide; Pain; Pain Measurement | 2019 |
Fungicide Tebuconazole Influences the Structure of Human Serum Albumin Molecule.
Topics: Calorimetry, Differential Scanning; Fungicides, Industrial; Humans; Ibuprofen; Ketoprofen; Molecular Docking Simulation; Protein Binding; Serum Albumin, Human; Spectrometry, Fluorescence; Thermodynamics; Triazoles | 2019 |
Hybrid monoliths with metal-organic frameworks in spin columns for extraction of non-steroidal drugs prior to their quantitation by reversed-phase HPLC.
Topics: Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Flurbiprofen; Humans; Ibuprofen; Ketoprofen; Limit of Detection; Metal-Organic Frameworks; Methylmethacrylates; Solid Phase Microextraction | 2019 |
Monitoring the release of anti-inflammatory and analgesic pharmaceuticals in the receiving environment.
Topics: Analgesics; Anti-Inflammatory Agents; Diclofenac; Environmental Monitoring; Hospitals; Humans; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Seasons; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2019 |
Structural investigations of stereoselective profen binding by equine and leporine serum albumins.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Calorimetry; Crystallography, X-Ray; Hares; Horses; Ibuprofen; Ketoprofen; Models, Molecular; Protein Conformation; Serum Albumin; Stereoisomerism; Suprofen; Thermodynamics | 2020 |
UPLC-based assay to assess the hydrophobicity of Antibody-Drug Conjugate (ADC) payloads.
Topics: Biological Assay; Calicheamicins; Chromatography, High Pressure Liquid; Doxorubicin; Flurbiprofen; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Immunoconjugates; Irinotecan; Ketoprofen; Maytansine; Molecular Conformation; Norfloxacin; Pentachlorophenol; Protein Multimerization; Structure-Activity Relationship; Tandem Mass Spectrometry; Tolnaftate | 2020 |
Diet quality and NSAIDs promote changes in formation of prostaglandins by an aquatic invertebrate.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Diclofenac; Diet; Ibuprofen; Invertebrates; Ketoprofen; Lipid Metabolism; Naproxen; Prostaglandins | 2020 |
Adsorption of ibuprofen, ketoprofen, and paracetamol onto activated carbon prepared from effluent treatment plant sludge of the beverage industry.
Topics: Acetaminophen; Adsorption; Anti-Inflammatory Agents, Non-Steroidal; Beverages; Charcoal; Humans; Ibuprofen; Ketoprofen; Kinetics; Sewage; Waste Disposal, Fluid; Wastewater; Water; Water Pollutants, Chemical | 2021 |
Antinociception produced by nonsteroidal anti-inflammatory drugs in female vs male rats.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Freund's Adjuvant; Hyperalgesia; Ibuprofen; Inflammation; Ketoprofen; Male; Pain; Rats; Rats, Sprague-Dawley; Sex Factors | 2021 |
Fixed Drug Eruption After Ingestion of Naproxen in a Patient Who Tolerated Ibuprofen and Dexketoprofen.
Topics: Administration, Oral; Adult; Allergens; Anti-Inflammatory Agents, Non-Steroidal; Drug Eruptions; Female; Humans; Ibuprofen; Immunization; Ketoprofen; Naproxen; Tromethamine | 2021 |
Facile and highly efficient three-phase single drop microextraction in-line coupled with capillary electrophoresis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Electrophoresis, Capillary; Humans; Ibuprofen; Ketoprofen; Naproxen | 2021 |
In-sewer stability of selected analgesics and their metabolites.
Topics: Analgesics; Carboxylic Acids; Diclofenac; Ibuprofen; Ketoprofen | 2021 |
Modeling of Adhesion in Tablet Compression at the Molecular Level Using Thermal Analysis and Molecular Simulations.
Topics: Adhesiveness; Calorimetry, Differential Scanning; Compressive Strength; Flurbiprofen; Ibuprofen; Ketoprofen; Models, Molecular; Tablets | 2022 |
Enhancement of the Anti-Inflammatory Activity of NSAIDs by Their Conjugation with 3,4,5-Trimethoxybenzyl Alcohol.
Topics: Amino Acids; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Edema; Ibuprofen; Ketoprofen; Molecular Docking Simulation; Rats | 2022 |
Disposable stochastic sensors for fast analysis of ibuprofen, ketoprofen, and flurbiprofen in their topical pharmaceutical formulations.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Carbon; Copper; Drug Compounding; Flurbiprofen; Ibuprofen; Ketoprofen | 2022 |
Pharmaceuticals and personal care products (PPCPs) in water, sediment and freshwater mollusks of the Dongting Lake downstream the Three Gorges Dam.
Topics: Animals; China; Cosmetics; Ecosystem; Environmental Monitoring; Geologic Sediments; Ibuprofen; Ketoprofen; Lakes; Mollusca; Pharmaceutical Preparations; Risk Assessment; Water; Water Pollutants, Chemical | 2022 |
An Evolving Role of Aqueous Piperazine to Improve the Solubility of Non-Steroidal Anti-Inflammatory Drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Flurbiprofen; Ibuprofen; Indomethacin; Ketoprofen; Phenylbutazone; Piperazine; Powders; Salts; Solubility; Spectroscopy, Fourier Transform Infrared; Sulindac; Water; X-Ray Diffraction | 2022 |
Rapid determination of NSAIDs by capillary and microchip electrophoresis with capacitively coupled contactless conductivity detection in wastewater.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Electric Conductivity; Electrophoresis, Capillary; Electrophoresis, Microchip; Ibuprofen; Ketoprofen; Methanol; Pharmaceutical Preparations; Wastewater | 2022 |
Fully soluble polymeric foams for in-vial dried blood spot collection and analysis of acidic drugs by capillary electrophoresis.
Topics: Electrophoresis, Capillary; Ibuprofen; Ketoprofen; Naproxen; Solvents | 2023 |
Differential Effects of Nonsteroidal Anti-Inflammatory Drugs in an In Vitro Model of Human Leaky Gut.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Ketoprofen; Oxidative Stress | 2023 |
Neonicotinoids and pharmaceuticals in hair of the Red fox (Vulpes vulpes) from the Cavallino-Treporti peninsula, Italy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Foxes; Hair; Humans; Ibuprofen; Insecticides; Italy; Ketoprofen; Neonicotinoids; Pharmaceutical Preparations; Sertraline | 2023 |
Advanced oxidation and a metrological strategy based on CLC-MS for the removal of pharmaceuticals from pore & surface water.
Topics: Diclofenac; Ibuprofen; Ketoprofen; Pharmaceutical Preparations; Water; Water Pollutants, Chemical | 2023 |
Effect of biosolids amendment on the fate and mobility of non-steroidal anti-inflammatory drugs (NSAIDs) in a field-based lysimeter cell study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biosolids; Ibuprofen; Ketoprofen; Naproxen; Sand; Soil; Soil Pollutants | 2023 |
On-farm Occurrence of Pharmaceuticals and Their Environmental Hazard: Case Study of a Tropical Dairy farm.
Topics: Acetaminophen; Animals; Caffeine; Carbamazepine; Environmental Monitoring; Farms; Ibuprofen; Ketoprofen; Pharmaceutical Preparations; Risperidone; Wastewater; Water; Water Pollutants, Chemical | 2023 |