ibuprofen and itraconazole

ibuprofen has been researched along with itraconazole in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (27.78)29.6817
2010's12 (66.67)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Guo, M; Li, C; Li, YR; Liu, JC; Piao, HR; Sun, LP; Zhang, TY; Zheng, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Costa-de-Oliveira, S; Mårdh, PA; Pina-Vaz, C; Ricardo, E; Rodrigues, AG1
Augustijns, P; Chen, H; Jammaer, JA; Martens, JA; Mellaerts, R; Van den Mooter, G; Van Humbeeck, J; Van Speybroeck, M1
Alves, SH; Azevedo, MI; Rossato, L; Santurio, JM; Spader, TB; Tronco-Alves, GR; Venturini, TP; Weiler, CB1
Alves, SH; Argenta, JS; Cavalheiro, AS; Ferreiro, L; Maboni, G; Pereira, DI; Pereira, PL; Pötter, L; Sallis, ES; Santurio, JM; Silveira, F; Zanette, RA1
Backhuijs, F; Martens, JA; Van den Mooter, G; Vialpando, M1
Aarons, L; Johnson, TN; Ogungbenro, K; Rostami-Hodjegan, A; Salem, F; Vajjah, P1
Bartoszewicz, M; Król, J; Nawrot, U1

Reviews

1 review(s) available for ibuprofen and itraconazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

17 other study(ies) available for ibuprofen and itraconazole

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Synthesis and biological evaluation of 1,3-diaryl pyrazole derivatives as potential antibacterial and anti-inflammatory agents.
    Bioorganic & medicinal chemistry letters, 2015, Nov-15, Volume: 25, Issue:22

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Candida albicans; Drug Resistance, Multiple, Bacterial; Furans; Gram-Negative Bacteria; Gram-Positive Cocci; Ibuprofen; Indomethacin; Mice; Pyrazoles

2015
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Potent synergic effect between ibuprofen and azoles on Candida resulting from blockade of efflux pumps as determined by FUN-1 staining and flow cytometry.
    The Journal of antimicrobial chemotherapy, 2005, Volume: 56, Issue:4

    Topics: Antifungal Agents; Candida; Drug Resistance, Fungal; Drug Synergism; Flow Cytometry; Fluconazole; Fungal Proteins; Ibuprofen; Itraconazole; Microbial Sensitivity Tests; Pyrimidines; Staining and Labeling; Triazoles; Voriconazole

2005
Physical state of poorly water soluble therapeutic molecules loaded into SBA-15 ordered mesoporous silica carriers: a case study with itraconazole and ibuprofen.
    Langmuir : the ACS journal of surfaces and colloids, 2008, Aug-19, Volume: 24, Issue:16

    Topics: Calorimetry, Differential Scanning; Computer Simulation; Ibuprofen; Itraconazole; Molecular Structure; Porosity; Silicon Dioxide; Solubility; Water

2008
In vitro synergisms obtained by amphotericin B and voriconazole associated with non-antifungal agents against Fusarium spp.
    Diagnostic microbiology and infectious disease, 2011, Volume: 71, Issue:2

    Topics: Amphotericin B; Antifungal Agents; Drug Synergism; Fungi; Fusarium; Ibuprofen; Itraconazole; Microbial Sensitivity Tests; Pyrimidines; Triazoles; Voriconazole

2011
In vitro and in vivo susceptibility of two-drug and three-drug combinations of terbinafine, itraconazole, caspofungin, ibuprofen and fluvastatin against Pythium insidiosum.
    Veterinary microbiology, 2012, May-25, Volume: 157, Issue:1-2

    Topics: Animals; Antifungal Agents; Caspofungin; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Echinocandins; Fatty Acids, Monounsaturated; Fluvastatin; Ibuprofen; Indoles; Itraconazole; Lipopeptides; Male; Microbial Sensitivity Tests; Naphthalenes; Pythiosis; Pythium; Rabbits; Terbinafine

2012
Risk assessment of premature drug release during wet granulation of ordered mesoporous silica loaded with poorly soluble compounds itraconazole, fenofibrate, naproxen, and ibuprofen.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2012, Volume: 81, Issue:1

    Topics: Calorimetry, Differential Scanning; Carboxymethylcellulose Sodium; Excipients; Fenofibrate; Ibuprofen; Itraconazole; Naproxen; Particle Size; Porosity; Powders; Risk Assessment; Silicon Dioxide; Solubility; Temperature

2012
Precision criteria to derive sample size when designing pediatric pharmacokinetic studies: which measure of variability should be used?
    Journal of clinical pharmacology, 2014, Volume: 54, Issue:3

    Topics: Adult; Area Under Curve; Biomedical Research; Caffeine; Child; Child, Preschool; Female; Humans; Ibuprofen; Infant; Infant, Newborn; Itraconazole; Male; Midazolam; Models, Biological; Pharmacokinetics; Sample Size; Theophylline

2014
Anti-candidal activity of selected analgesic drugs used alone and in combination with fluconazole, itraconazole, voriconazole, posaconazole and isavuconazole.
    Journal de mycologie medicale, 2018, Volume: 28, Issue:2

    Topics: Acetaminophen; Analgesics; Antifungal Agents; Aspirin; Candida; Candida albicans; Candida glabrata; Candidiasis; Dipyrone; Drug Resistance, Fungal; Fluconazole; Humans; Ibuprofen; Itraconazole; Meloxicam; Microbial Sensitivity Tests; Nitriles; Pyridines; Triazoles; Voriconazole

2018