ibuprofen has been researched along with indomethacin in 902 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 332 (36.81) | 18.7374 |
| 1990's | 149 (16.52) | 18.2507 |
| 2000's | 163 (18.07) | 29.6817 |
| 2010's | 198 (21.95) | 24.3611 |
| 2020's | 60 (6.65) | 2.80 |
| Authors | Studies |
|---|---|
| Clark, RL; Lanza, T; Pessolano, AA; Risley, EA; Shen, TY; Van Arman, CG; Witzel, B | 1 |
| Heikes, JE; Sprague, PW | 1 |
| Hannah, J; Holtz, WJ; Houser, RA; Jones, H; Kelly, KW; Matzuk, AR; Ruyle, WV; Sarett, LH; Shen, TY; Witzel, BE | 1 |
| Bell, MR; D'Ambra, TE; Daum, SJ; Eissenstat, MA; Herrmann, JL; Hlasta, DJ; Kumar, V; Philion, RE; Rosi, D; Wetzel, JR | 1 |
| Carty, TJ; Moore, PF; Mylari, BL; Zembrowski, WJ | 1 |
| Capiris, T; Cetenko, WJ; Connor, DT; Dyer, RD; Flynn, DL; Kostlan, CR; Nies, DE; Schrier, DJ; Sircar, JC | 1 |
| Lazer, ES; Matteo, MR; Possanza, GJ | 1 |
| Millonig, RC; Rovnyak, GC; Schwartz, J; Shu, V | 1 |
| Behn, DC; Botton, I; Fellows, CA; Laskowski, SC; Phillips, DK; Schlegel, DC; Speight, PT; Zenitz, BL | 1 |
| Iizuka, Y; Misaka, E; Naruto, S; Tanaka, S; Terada, A; Wachi, K | 1 |
| Boettcher, I; Elger, W; Kirsch, G; Siegmund, F; Wachtel, H | 1 |
| Ariyan, ZS; Fogt, SW; Heilman, RD; Matthews, RJ; Powers, LJ; Rippin, DJ | 1 |
| Copeland, RA; Covington, M; Trzaskos, JM; Wilkerson, WW | 1 |
| Galbraith, W; Gans-Brangs, K; Grubb, M; Hewes, WE; Jaffee, B; Kenney, JP; Kerr, J; Wilkerson, WW; Wong, N | 1 |
| Allen, RC; Bailey, SC; Elliott, ME; Freed, BS; Hamer, RR; Hellyer, L; Helsley, GC; Kurtz, ES; Martin, LL; Przekop, P; Tegeler, JJ; White, J | 1 |
| Bell, RL; Bouska, J; Brooks, CD; Carter, GW; Dellaria, JF; Hulkower, KI; Kolasa, T; Rodriques, KE; Summers, JB | 1 |
| Inui, KI; Masuda, S; Saito, H | 1 |
| Bohlin, L; Danielson, H; Noreen, Y; Perera, P; Ringbom, T | 1 |
| Bohlin, L; Noreen, Y; Perera, P; Ringbom, T; Segura, L | 1 |
| Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S | 1 |
| Cha, SH; Endou, H; Kanai, Y; Kim, DK; Kim, JY; Kusuhara, H; Sekine, T; Sugiyama, Y; Yu, E | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Cihlar, T; Ho, ES; Mulato, AS | 1 |
| Inui, K; Saito, H; Uwai, Y | 1 |
| Cha, SH; Endou, H; Fukushima , JI; Goya, T; Kanai, Y; Kobayashi, Y; Sekine, T | 1 |
| Abe, T; Itoh, T; Kato, Y; Kusuhara, H; Meier, PJ; Shitara, Y; Sugiyama, D; Sugiyama, Y | 1 |
| Cha, SH; Endou, H; Hosoyamada, M; Khamdang, S; Kimura, H; Narikawa, S; Sekine, T; Takeda, M | 1 |
| Borst, P; de Haas, M; Kuil, A; Reid, G; van der Heijden, I; Wielinga, P; Wijnholds, J; Zelcer, N | 1 |
| Faassen, F; Spanings, H; Vogel, G; Vromans, H | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Charitos, C; Doulgkeris, C; Galanakis, D; Gavalas, A; Kourounakis, AP; Kourounakis, PN; Kravaritou, C; Rekka, EA; Tsiakitzis, KC | 1 |
| Beroza, P; Cai, D; Damodaran, K; Gomez, RF; Hsu, N; Keck, JG; Laborde, E; Lum, RT; Macke, TJ; Martin, G; Schow, SR; Simon, RJ; Villar, HO; Wick, MM | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A | 1 |
| Caron, G; Ermondi, G | 1 |
| Knaus, EE; Praveen Rao, PN; Velázquez, C | 1 |
| Backlund, A; Bohlin, L; Gottfries, J; Larsson, J | 1 |
| Bain, G; Beher, D; Chen, W; Jiang, X; Munoz, B; Peachey, J; Prasit, P; Shearman, MS; St-Jacques, R; Stock, N; Williamson, TL; Wrigley, JD | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| El-Fayomi, HM; El-Sadek, ME; Lashine, el-SM; Metwally, KA; Yaseen, SH | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Citro, ML; Keefer, LK; Knaus, EE; Praveen Rao, PN; Velázquez, CA | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Barreiro, EJ; Fraga, CA; Lima, LM; Romeiro, NC; Sant'Anna, CM | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Bhole, RP; Bhusari, KP; Chikhale, RV; Khedekar, PB | 1 |
| Abdellatif, KR; Chowdhury, MA; Das, D; Dong, Y; Knaus, EE; Suresh, MR; Velázquez, CA; Yu, G | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Björklund, E; Congiu, C; Fowler, CJ; Hempel, F; Onnis, V; Söderström, E | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Avdeef, A; Tam, KY | 1 |
| Baumann, K; Dittrich, M; Greiner, C; Hieke, M; Ness, J; Schubert-Zsilavecz, M; Steri, R; Weggen, S; Werz, O; Zettl, H | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P | 1 |
| Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Abdellatif, KR; Chowdhury, MA; DuMond, JF; Huang, Z; King, SB; Knaus, EE; Reisz, JA; Velázquez, CA | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Greiner, C; Hieke, M; Ness, J; Schubert-Zsilavecz, M; Steri, R; Weggen, S; Werz, O; Zettl, H | 1 |
| El Gendy, MA; Jain, S; Jurasz, P; Kashfi, K; Tran, S; Velázquez-Martínez, CA | 1 |
| Alam, MM; Alam, MS; Kalle, AM; Mulakayala, C; Mulakayala, N; Pallu, R; Shafi, S; Vanaja, G | 1 |
| Gust, R; Huang, W; Liu, W; Qian, H; Zhang, H; Zhang, T; Zhou, J; Zhu, H | 1 |
| Kumar, M; Sinha, VR; Thareja, S | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cheng, Y; Gust, R; Liu, W; Zhang, H; Zhang, T; Zhou, J; Zhu, H | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Ambrosi, G; Bauer, J; Elkady, M; Laufer, SA; Luderer, S; Nieß, R; Schaible, AM; Werz, O | 1 |
| Bruno, A; Dovizio, M; Lavecchia, A; Malerba, P; Marcantoni, E; Patrignani, P; Perrone, MG; Scilimati, A; Simone, L; Tacconelli, S; Vitale, P | 1 |
| Bairwa, K; Grover, J; Jachak, SM; Roy, SK; Singh, IN; Srivastava, A | 1 |
| Capim, SL; Dos Santos, GC; Gonçalves, GM; Marinho, BG; Vasconcellos, ML | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Bairwa, K; Grover, J; Jachak, SM; Kumar, V; Singh, V; Sobhia, ME | 1 |
| Bansal, Y; Kaur, M; Silakari, O | 1 |
| Brewster, C; Deering-Rice, CE; Reilly, CA; Rose, TM | 1 |
| Alcaraz, B; Bratoeff, E; Cabeza, M; Camacho-Arroyo, I; Garrido, M; González-Arenas, A | 1 |
| Bharate, SS; Vishwakarma, RA | 1 |
| Chen, T; Guan, J; Liao, J; Luo, J; Qin, X; Talley, JJ; Tortorella, MD; Tu, Z; Zhang, Y | 1 |
| Guo, M; Li, C; Li, YR; Liu, JC; Piao, HR; Sun, LP; Zhang, TY; Zheng, CJ | 1 |
| Kourounakis, PN; Kourti, M; Rekka, EA; Theodosis-Nobelos, P; Tziona, P | 1 |
| Bennis, K; Ducki, S; Lesage, F; Vivier, D | 1 |
| Gavalas, A; Kourti, M; Rekka, EA; Theodosis-Nobelos, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Chi, KQ; Liu, HY; Piao, HR; Sun, LP; Wei, ZY; Yu, ZK; Zheng, CJ | 1 |
| Chen, Y; Liu, L; Nie, X; Shi, D; Wang, J; Wang, Y; Wei, G; Zhang, L; Zheng, C | 1 |
| Kongsaeree, P; Lhinhatrakool, T; Prabpai, S; Seeka, C; Sutthivaiyakit, S; Tewtrakul, S | 1 |
| Cao, Q; Gong, GH; Quan, ZS; Wang, XZ; Zhang, HJ | 1 |
| Amir, M; Somakala, K; Tariq, S | 1 |
| Camps, I; Castelli, MR; Castro, NG; D'Alincourt da Fonseca Peçanha, D; da Silva, FMR; Dardenne, LE; de Freitas Silva, M; de Oliveira Carneiro Junior, W; Dias Viegas, FP; Divino da Rocha, M; Ferreira, FF; Ferreira-Silva, GÁ; Giusti-Paiva, A; Gontijo, VS; Guedes, IA; Ionta, M; Leomil Coelho, LF; Machado, RP; Mancini, KC; Marques de Oliveira, PC; Morais, ÉP; Neves, GA; Orlandi, L; Pereira, RM; Pinheiro de Oliveira, AC; Pruccoli, L; Quaglio Bellozi, PM; Riquiel, MM; Simões de Lima, LM; Tarozzi, A; Vaz, SM; Veloso, MP; Viegas, C; Vilela, FC | 1 |
| Boixareu, N; Campanera, JM; Navarro, L; Pors, K; Pouplana, R; Pujol, MD; Rosell, G; Sánchez, S | 1 |
| Abdel-Maksoud, MS; Ali, EMH; Oh, CH | 1 |
| Capito, JE; El-Manawaty, MA; George, RF; Girgis, AS; Panda, SS; Salman, A; Samir, A; Thomas, SJ | 1 |
| Daniel Pedro-Hernández, L; Hernández-Montalbán, C; Martínez-García, M; Martínez-Klimova, E; Ramírez-Ápan, T | 1 |
| Neha, K; Wakode, S | 1 |
| Bachmann, M; Brandt, F; Kopka, K; Laube, M; Löser, R; Pietzsch, HJ; Pietzsch, J; Ullrich, M; van den Hoff, J; Wodtke, R | 1 |
| Bajpai, A; Basu, S; Chhabria, D; Kirubakaran, S; Mishra, T | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Anderson, JA; Buchanan, WW; Lee, P; Miller, J; Webb, J | 1 |
| Halpern, LM | 1 |
| Huskisson, EC | 1 |
| Akimoto, T; Saito, T; Tachizawa, H; Tsukada, W | 1 |
| Buisseret, PD; Heinzelmann, DI; Lessof, MH; Youlten, LF | 1 |
| Kawai, K; Kuzuna, S; Morimoto, S | 1 |
| Nozu, K | 1 |
| Cavalli-Björkman, K; Jacobson, J; Lundström, V; Nilsson, B; Norbeck, M | 1 |
| Gerrard, JM; Peterson, DA; Rao, GH; White, JG | 1 |
| Arrigoni-Martelli, E; Binderup, L; Bramm, E | 1 |
| Hearron, MS; Miyara, A; Moxley, TE; Royer, GL; Shenker, BM | 1 |
| Mehta, J; Simchowitz, L; Spilberg, I | 1 |
| Horton, R; Stone, RA; Zia, P; Zipser, RD | 1 |
| Brewer, EJ | 1 |
| Brown, KA; Collins, AJ | 1 |
| Kunin, CM; Proctor, RA | 1 |
| Anania, MC; Nencini, P; Paroli, E | 1 |
| Roe, RL | 1 |
| Adkinson, NF; Kordansky, D; Norman, PS; Rosenthal, RR | 1 |
| Cohen, GN; Fisherman, EW | 1 |
| Busson, M; Valtonen, EJ | 1 |
| Ferry, DG; McArthur, AW; Palmer, DG | 1 |
| Burdeĭnyĭ, AP | 1 |
| Gothoni, G; Rejholec, V; Tokola, O; Vapaatalo, H | 1 |
| Balogh, Z; Buchanan, WW; MacLeod, M; Papazoglou, SN | 1 |
| Chen, M; Robertson, RP | 1 |
| Bonomo, I | 1 |
| Janas-Boratyńska, M; Szewczyk, Z | 1 |
| Szary, A | 1 |
| Alphen, GW; Wilhelm, PB | 1 |
| Glenn, TM; Wilkerson, RD | 1 |
| Bowden, RE; Gill, JR; Keiser, HR; Radfar, N; Taylor, AA | 1 |
| Hoefs, JC; Horton, R; Speckart, PF; Zia, PK; Zipser, RD | 1 |
| Fichman, MP; Rude, RK; Zia, PK; Zipser, RD | 1 |
| Spisani, S; Traniello, S; Vanzini, G | 1 |
| MacCarthy, EP; Stokes, GS | 1 |
| Ishikawa, Y; Wada, T | 1 |
| Cioli, V; Corradino, C; Putzolu, S; Rossi, V; Scorza Barcellona, P | 1 |
| Chen, TT; Lanza, FL; Nelson, RS; Rack, MF; Royer, GL; Seckman, CE | 2 |
| Sasaki, H | 1 |
| Ciccolunghi, SN; Reddrop, R; Schubiger, BI | 1 |
| Ohtsuki, H; Okabe, S; Tabata, K | 1 |
| Horton, R; Kaye, Z; Mayeda, S; Zia, PK; Zipser, RD | 1 |
| Gieldanowski, J | 1 |
| Boer, P; Dorhout Mees, EJ; Geyskes, GG; Radó, JP; Simatupang, TA; Vos, J | 1 |
| Bourel, M; Chales, G; Grosbois, B; Lenoir, P; Louboutin, YB; Pawlotsky, Y | 1 |
| Baranova, EIa; Dormidontov, EN; Korshunov, NI | 2 |
| Brooks, PM | 1 |
| Nagai, T; Nambu, N; Shimoda, M; Takahashi, Y; Ueda, H | 1 |
| Demers, LM; Halbert, DR | 1 |
| de Blécourt, JJ | 1 |
| Burry, HC; Dieppe, PA; Grahame, R; Perera, T | 1 |
| Kaye, RL; Pemberton, RE | 1 |
| Rosenthal, SH; Sack, KE | 1 |
| Grahame, R | 1 |
| Donovan, JF; Hearron, MS; Miyara, A; Moxley, TE; Royer, GL | 1 |
| Smiley, JD | 1 |
| Bartter, FC; Bowden, RE; Frölich, JC; Gill, JR; Keiser, HR; Oates, JA; Seyberth, HW; Taylor, AA | 1 |
| Bacon, PA; Chan, R; Collins, AJ; Crook, D | 1 |
| Bartter, FC; Bowden, RE; Frolich, JC; Gill, JR; Hollifield, JW; Keiser, HR; Oates, JA; Radfar, N; Seyberth, H; Taylor, AA | 1 |
| Denman, SJ; Lourie, SH; Schroeder, ET | 1 |
| Turner, R | 1 |
| Bishai, I; Bodach, E; Coceani, F; Heaton, J; Nashat, M; Olley, PM; White, E | 1 |
| Ikeda, S; Tanaka, M; Uchiyama, M | 1 |
| Milazzo, S | 1 |
| Keinänen, S; Kouvalainen, K; Similä, S | 1 |
| Kitchen, EA; Meacock, SC | 1 |
| Docken, W; Kantrowitz, FG | 1 |
| Fitzpatrick, FA; Wynalda, MA | 1 |
| Ghosh, P; Horsburgh, BA; McKenzie, LS; Taylor, TK | 1 |
| Guyonnet, JC; Julou, L | 1 |
| Lands, WE; Rome, LH | 1 |
| Biundo, JJ; Gum, OB; Weiss, TE | 1 |
| McBeath, AA | 1 |
| Shearman, RP; Smith, ID; Temple, DM | 1 |
| Deodger, ShD; Dik, VS; Grennan, DM; Li, P; Starrok, RD | 1 |
| Havelka, S; Hoza, J; Rubín, A | 1 |
| Jin, N; Packer, CS; Patterson, CE; Rhoades, RA | 1 |
| Hla, T; Neilson, K | 1 |
| Chand, D; Gupta, OP; Sharma, N | 1 |
| Gadina, M; Ghezzi, P; Kankova, M; Mantovani, A; Riganti, F; Sironi, M; Zandalasini, M | 1 |
| Aranda, JV; Chemtob, S; Malcolm, D; Parys-Van Ginderdeuren, R; Varma, DR | 1 |
| Baynes, RE; Jones, RD; Nimitz, CT | 1 |
| Ehrhart, IC; el-Kashef, HA; Endrédi, J; Hofman, WF | 1 |
| Bonnet, P; Bourdeau, A; Herviaux, P; Lieberherr, M; Sachs, C; Souberbielle, JC | 1 |
| Frangos, JA; Hsieh, HJ; Li, NQ | 1 |
| Blower, PR; Coates, ME; Melarange, R; Moore, G; Ronaasen, V; Ward, FW | 1 |
| Benincosa, LJ; Morris, ME | 1 |
| Deyrup-Olsen, I; Louie, H; Luchtel, DL; Martin, AW | 1 |
| Bohan, DF; Caruana, C; Francom, SF; Holland, M; Hughes, GS; Means, LK | 1 |
| Drews, G; Garrino, MG; Henquin, JC | 1 |
| Chan, FP; Khoo, NK; Lala, PK; Saarloos, MN | 1 |
| Chen, M; Fiscus, RR; Han, C; Wang, X; Yang, L | 1 |
| Dorman, RV | 1 |
| Sansano, S; Wiesenberg-Böttcher, I; Zimmerli, W | 1 |
| Chen, MZ; Han, QD; Wang, XA; Yang, LH | 1 |
| Bright, TP; McNulty, CJ | 1 |
| Toczołowski, J | 1 |
| Maibach, HI; Surber, C; Wilhelm, KP | 2 |
| Blackburn, WD; Chatham, WW; Heck, LW; Loose, LD | 1 |
| Gross, NJ; Holloway, NO; Narine, KR | 1 |
| Aranda, JV; Barna, T; Beharry, K; Chemtob, S; Varma, DR | 1 |
| Raineri-Gerber, I; von Felten, A | 1 |
| Barthwal, M; Srivastava, K | 1 |
| Bradley, JD; Dahms, TE; Webster, RO; Zanaboni, PB | 1 |
| Gough, DB; Grbic, JT; Mannick, JA; Rodrick, ML | 1 |
| Ehrlich, HP; Rockwell, WB | 1 |
| Dodds, PF; Hutson, DH; Moorhouse, KG | 1 |
| Christensen, HR; Jørgensen, HS; Kampmann, JP | 1 |
| Chandrasekaran, AN; Krishnamurthy, V; Madhavan, R; Parthiban, M; Porkodi, R; Subramaniam, R | 1 |
| Casady, RL; Itoh, T; Magavi, R; Nishihata, T; Rytting, JH | 1 |
| Agarwal, PK; Chandra, M; Misra, R; Pandey, H; Pandeya, SN | 1 |
| Laychock, SG | 1 |
| Alyea, EP; Bernier, M; Hearse, DJ | 1 |
| Aurelian, L; Burnett, JW; Wachsman, M | 1 |
| Bruner, CA; Lee, L; Webb, RC | 1 |
| Momma, K; Takao, A | 1 |
| Connell, MJ; Ferrari, RA; Haubrich, DR; Perrone, MH; Van Liew, DK; Ward, SJ; Zobre, CM | 1 |
| Copeland, S; Johnston, GD; Passmore, AP | 2 |
| Gardner, TJ; Horneffer, PJ; Miller, RH; Pearson, TA; Reitz, BA; Rykiel, MF | 1 |
| Dandona, P; Gill, J; Jeremy, JY | 1 |
| Brune, K; Dietzel, K; Nuernberg, B; Schneider, HT | 1 |
| Elliott, JP; Wiggins, DA | 1 |
| Friedman, MR | 1 |
| Brown, ZA; Hendricks, SK; Moore, DE; Smith, JR | 1 |
| Brune, K; Jurna, I | 1 |
| Czernielewski, J; Duteil, L; Ortonne, JP; Poncet, M; Queille, C | 1 |
| García-Sáinz, JA; Hernández-Sotomayor, SM; Macías-Silva, M | 1 |
| Gerok, W; Häussinger, D; vom Dahl, S; Wettstein, M | 1 |
| Bain, PA; Brown, DS; Campbell, GP; Hesketh, JE; Palmer, RM; Whitelaw, PF | 1 |
| Kadowitz, PJ; Mayeux, PR; McNamara, DB | 1 |
| Martin, SE; Patterson, RE | 1 |
| Easom, RA; Hughes, JH; McDaniel, ML; Turk, J; Wolf, BA | 1 |
| Danilowicz, M; Eling, TE; Luster, MI; Tucker, AN; Vore, SJ | 1 |
| Dasgupta, PK; Murthy, PS; Srivastava, AK; Srivastava, K | 1 |
| DeVos-Doyle, K; Lajos, TZ; Stern, MP; Viguera, MG | 1 |
| Jackson, EK | 1 |
| Basualdo, CA; Jugdutt, BI | 1 |
| Cornell, RP | 1 |
| Nikolov, A | 1 |
| Mills, W; Trancik, T; Vinson, N | 1 |
| Bernáth, Z; Buzás, G; Hajdu, A; Puscas, I | 1 |
| Bergamo, RR; Cominelli, F; Kopple, JD; Zipser, RD | 1 |
| Lee, HJ; McLean, HM | 1 |
| Kawakubo, H; Matsumoto, K; Nishikawa, K; Suehiro, S; Toyomaki, Y; Yago, H | 1 |
| Murayama, M; Namiki, Y | 1 |
| Curi, R; Homem-de-Bittencourt Júnior, PI; Lopes, OU; Pontieri, V | 1 |
| Fujiyoshi, T; Iida, H; Kuwashima, M; Uematsu, T | 1 |
| Abboud, FM; Chapleau, MW | 1 |
| Docherty, JC; Wilson, TW | 1 |
| Bennett, A; Capasso, F; Tavares, IA; Vine, ND | 1 |
| Faulkner, G; Langman, M; Somerville, K | 1 |
| Paulus, HE; Schlegel, SI | 1 |
| Collins-Williams, C | 1 |
| Fujimura, H; Hidaka, T; Hiramatsu, Y; Hosoe, K; Watanabe, K; Yamashita, T | 1 |
| Hogan, RD; Unthank, JL | 1 |
| Bird, H; Okala, B; Othman, H; Padwick, DJ; Smith, JA; Surrall, K | 1 |
| Breckwoldt, M; Zahradnik, HP | 1 |
| Hirsch, J; Ledger, WJ; Witkin, SS | 1 |
| Lanza, F; Lynn, M; Rack, MF; Sanda, M; Wolf, J | 1 |
| Barkley, M; Kimball, ES; Neuman, RG; Weichman, BM; Wilson, BD; Wood, DD | 1 |
| Ducatenzeiler, A; Menezes, J | 1 |
| Caplan, M; Hess, ML; Lucchesi, B; Romson, JL; Rowe, GT | 1 |
| Carlson, EJ; Goldstone, R; Horton, R; Hsueh, WA | 1 |
| Cordasco, DM; Rotrosen, J; Segarnick, DJ | 1 |
| Schuster, VL | 1 |
| Cheng, CY; Leggett, CG; Reese, AC | 1 |
| Harrison, H; Libber, S; Spector, D | 1 |
| Rampart, M; Williams, TJ | 1 |
| Sallmann, AR | 1 |
| Karmazyn, M | 1 |
| Karmali, RA; Marsh, J | 2 |
| Dahms, TE; Lonigro, AJ; Sprague, RS; Stephenson, AH | 1 |
| Kerwin, JL; Simmons, CA; Washino, RK | 1 |
| Cheng, HY; Donowitz, M; Sharp, GW | 1 |
| Dorman, RV; Schwartz, MA; Terrian, DM | 1 |
| Needleman, P; Tripp, CS; Unanue, ER; Wyche, A | 1 |
| Bosma, T; Goad, D; Lazzaro, M; Levine, L; Tashjian, AH; Voelkel, EF | 1 |
| Fiers, W; Goldberg, AL; Kettelhut, IC | 1 |
| Kuhn, DC; Stuart, MJ | 1 |
| Baxter, CS; Lawrence, AT | 1 |
| Lang, SA; Maron, MB | 1 |
| Benson, B; Logan, JL | 1 |
| Bischoff, SB; Dorman, RV; Schwartz, MA; Terrian, DM | 1 |
| Anderson, WP; Bobik, A | 1 |
| el Attar, TM; Lin, HS | 1 |
| Bjornson, AB; Bjornson, HS; Knippenberg, RW | 1 |
| Brune, K; Reinke, M | 1 |
| Nilsson, OS; Persson, PE; Sodemann, B | 2 |
| Bigby, M; Stern, R | 1 |
| Mitzner, WA; Wagner, EM | 1 |
| Bindiger, A; Nichter, LS | 1 |
| Ito, Y; Iwaki, M; Ogiso, T | 1 |
| Greenwood, A; Huskisson, EC | 1 |
| Hollenberg, MD; Itoh, H; Lederis, K; Muramatsu, I; Patel, P | 1 |
| Ishii, K; Kadokawa, T; Motoyoshi, S; Nakamura, H | 1 |
| Bone, RC; Jacobs, ER; Wilson, FJ | 1 |
| Giroud, JP; Hakim, J; Perianin, A | 1 |
| Endroczi, E; Koranyi, L; Kovacs, Z; Mohari, K; Tal, E | 1 |
| Diamantis, W; Gordon, R; Sofia, RD | 1 |
| Penning, TM; Smithgall, TE | 1 |
| Fligiel, SE; He, XM; Varani, J | 1 |
| Bjarnason, I; Levi, AJ; Peters, TJ; Smethurst, P; Williams, P | 1 |
| Fujiyoshi, T; Iida, H; Ikeda, K; Saito, M; Uematsu, T; Yamaura, T | 1 |
| Giercksky, KE | 1 |
| Amano, T; Kohno, Y; Suwa, T; Suzuki, A; Urano, H | 1 |
| Campese, V; Horton, R; McKay, M; Nadler, JL; Vrbanac, J | 1 |
| Zuckner, J | 1 |
| Altman, R | 1 |
| Sultan, C | 1 |
| Burke, J; Hales, C; Jung, W; Shinozawa, Y | 1 |
| Johansson, EA | 1 |
| Goldman, CD; Rudloff, MA; Ternberg, JL | 1 |
| de Jong, PE; Kallenberg, CG; Meyer, S; ter Borg, EJ; van Rijswijk, MH | 1 |
| Brigham, KL; Meyrick, B; Niedermeyer, ME; Okamoto, M | 1 |
| Bille-Hansen, V; Olsen, UB | 1 |
| DeLong, RE; Phillis, JW; Towner, JK | 1 |
| Del Maestro, RF; Farrell, CL; Reichman, HR | 1 |
| Tiegs, G; Wendel, A | 1 |
| Crossley, MJ; Hunneyball, IM; Spowage, M | 1 |
| Brunner, TR; Carlson, RP; Datko, LJ; Purvis, WF; Shaw, GW; Thompson, JL; Welch, TM | 1 |
| Ellis, EF; Gamache, DA | 1 |
| Caulin, C; Dahan, R; Isal, JP; Lagier, G; Simoneau, G | 1 |
| Cook, JA; Halushka, PV; Knapp, RG; Wise, WC | 1 |
| McGill, PE | 1 |
| Akita, S; Satoh, M; Takagi, H | 1 |
| Aihara, H; Higuchi, S; Otomo, S; Shioiri, Y; Tanaka, N | 1 |
| Brigham, KL | 1 |
| Berglund, B; Edlund, A; Kaijser, L; Nowak, J; Patrono, C; Sollevi, A; van Dorne, D; Wennmalm, A | 1 |
| Miyazaki, M; Toda, N; Yamamoto, M | 1 |
| Bagby, GF; O'Brien, WM | 1 |
| Bar, RS; Dolash, S; Kaduce, TL; Marshall, SJ; Sandra, A; Spector, AA | 1 |
| Odessey, R | 1 |
| Ferrier, GR; Karmazyn, M; Moffat, MP | 1 |
| Johnson, A; Malik, AB | 1 |
| Wallenstein, MC | 2 |
| Butler, WR; Figueroa, JP; Grandis, A; Handwerger, S; Huyler, SE; Mann, C; Mitchell, M; Nathanielsz, PW | 1 |
| Davis, D; Fairman, RP; Glauser, FL; Hammond, B; Monroe, P; Sugarman, H | 1 |
| Armstrong, ML; Field, FJ; Mathur, SN; Spector, AA | 1 |
| Kimble, EF; Kothari, HV; Ku, EC; Lee, W; Liauw, L; Tjan, J | 1 |
| diZerega, GS; Nakamura, RM; Shimanuki, T | 1 |
| Gasparich, JP; Mayo, ME | 1 |
| Buchanan, WW; Kassam, YB | 1 |
| Condorelli, M; Cuocolo, A; De Simone, A; Patrignani, P; Ricciardelli, B; Saccà, L; Trimarco, B; Volpe, M | 1 |
| Gilfillan, AM; Rooney, SA | 1 |
| Foley, RJ; Reeves, WB; Weinman, EJ | 1 |
| Jelić-Ivanović, Z; Majkić-Singh, N; Spasić, S; Todorović, P | 1 |
| Flowers, OV; Fortner, G; Kilpatrick, SJ; Reinhardt, LA; Streeter, WC; Wilkin, JK | 1 |
| Grover, GJ; Weiss, HR | 1 |
| Hudyma, EO; Kollenberg, LO; Robbins, JM | 1 |
| Machtey, I | 1 |
| Acosta, D; Sorensen, EM | 1 |
| Iizuka, Y; Tanaka, K | 1 |
| Johnson, KJ; Sulavik, MC; Ward, PA | 1 |
| Ellman, MH | 1 |
| Abramson, S; Edelson, H; Kaplan, H; Ludewig, R; Weissmann, G | 1 |
| Denzlinger, C; Hagmann, W; Keppler, D | 1 |
| Rampton, DS; Sladen, GE | 1 |
| Downie, JW; Karmazyn, M | 1 |
| Gupta, SL; Sarkar, FH | 1 |
| Alvarez, OM; Eaglstein, WH; Levendorf, KD; Mertz, PM; Smerbeck, RV | 1 |
| Anderson, RJ; Gerber, JG; Nies, AS; Schrier, RW | 1 |
| Aiken, JW | 1 |
| Fletcher, JR; Miller, MK; Short, BL; Stroud, CY | 1 |
| Pappius, HM; Wolfe, LS | 2 |
| Brown, RS; Salzman, E; Steer, M; Stemerman, M; Stoff, JS | 1 |
| Aiken, JW; Gorman, RR; Shebuski, RJ | 1 |
| Aiken, JW; Gorman, RR; Miller, OV; Shebuski, RJ | 1 |
| Goldstone, R; Horton, R; Martin, K; Zipser, R | 1 |
| Canfield, SP; Spencer, JE | 1 |
| Claman, HN; Hansbrough, J; Peterson, V; Zapata-Sirvent, R | 1 |
| Butler, RR; Cook, JA; Halushka, PV; Wise, WC | 1 |
| Chan, WY | 1 |
| Calin, A | 1 |
| Clarke, TK; Mungavin, JM | 1 |
| Forman, ES; Gookin, KS; Morrison, JC; Vecchio, TJ; Wiser, WL | 1 |
| Casey, LC; Fink, MP; MacVittie, TJ | 2 |
| Fischer, GW; Golden, SM; Hemming, VG; Noble, SF; O'Brien, WF | 1 |
| Altman, RD | 1 |
| Ward, JR | 1 |
| Melvin, JR; Osyamkpe, CO; Sanfilippo, JS; Teichman, J; Wittliff, JL | 1 |
| Bonney, RJ; Galavage, M; Goldenberg, M; Humes, JL; Kuehl, FA; Sadowski, S; Subers, E | 1 |
| Hoak, JC | 1 |
| Carlsson, I; Wennmalm, A | 1 |
| Owen, PR | 1 |
| Furst, DE | 1 |
| Goodwin, JS | 1 |
| Bailey, JM; Ekborg, SL; Vanderhoek, JY | 1 |
| Bjelle, A; Mjörndal, T | 1 |
| Dunn, MJ | 1 |
| Holingsworth, EB; Patrick, GA | 1 |
| Giri, SN; Scheinholtz, RM; Schwartz, LW; Siegel, DM | 1 |
| Alessandrini, A; Gemini, R | 1 |
| Lanza, FL | 1 |
| Giroud, JP; Hakim, J; Perianin, A; Roch-Arveiller, M | 1 |
| Bhalla, AK; Simon, LS | 1 |
| Paradisi, L; Parola, M; Torrielli, MV | 1 |
| Cronberg, S; Söderberg, I; Wallmark, E | 1 |
| Mashiah, V; Yaron, I; Yaron, M | 1 |
| Davies, J; Fletcher, J; Sheppard, K | 1 |
| Court, H; Volans, GN | 1 |
| Ehrlich, HP | 1 |
| Elattar, TM; Lin, HS; Tira, DE | 1 |
| Aihara, H; Amanuma, F; Hashimoto, S; Kameyama, T; Okuyama, S; Orikasa, S; Sakagawa, T; Tarumoto, Y; Tsutsui, Y; Yamada, C | 1 |
| Bartter, FC; Chan, JC; Gill, JR | 1 |
| Diwan, PV; Kulkarni, DR | 1 |
| Cikrit, D; Grosfeld, JL; Gross, K; Kamman, K; Katz, S; Ross, D; Weber, TR; Wolfe, M | 1 |
| Isomäki, H; Kaarela, K; Kajander, A; Koota, K; Lehtinen, K; Luukkainen, R; Martio, J; Martio, T; Nissilä, M; Nuotio, P | 1 |
| Fox, DA; Jick, H | 1 |
| De Leon, FD; Sanfilippo, JS; Toledo, AA; Yussman, MA | 1 |
| Babayan, RK; Krane, RJ; Kraus, SE; Siroky, MB | 1 |
| Albrecht, RF; Hoffman, WE; Miletich, DJ; Pelligrino, D | 1 |
| Obel, AO | 1 |
| Ciofalo, VB; Diamantis, W; Melton, J; Sofia, RD | 1 |
| Fraser, IS | 1 |
| Avery, GS; Brogden, RN; Heel, RC; Pakes, GE; Speight, TM | 1 |
| Barabino, A; Corsini, G; Puppo, F; Zavarise, GM | 1 |
| Ballard, JO; Eyster, ME; Gordon, RA | 1 |
| Metz, SA | 1 |
| Kuna, ST; Levine, S | 1 |
| Fujimori, I; Fukui, M; Hara, K; Hayakawa, Y; Hayashida, K; Horiuchi, N; Ikebe, A; Izumikawa, K; Kaji, M; Kashiwagi, S; Katayama, T; Kitamoto, O; Kobayashi, H; Kohno, M; Komori, M; Sekita, K; Shingu, T; Suzuyama, Y; Tanaka, T; Yamaguchi, K | 1 |
| Arruda, JA | 1 |
| Alvin, PE; Litt, IF | 1 |
| Chang, TW | 1 |
| Bennedsen, J; Nielsen, H | 1 |
| Blackshear, JL; Davidman, M; Stillman, MT | 1 |
| Bailey, RR; Lynn, KL; Munn, E | 1 |
| Cook, JA; Halushka, PV; Wise, WC | 1 |
| Zizic, TM | 1 |
| Barrett, DC; Bunton, RW; Palmer, DG | 1 |
| Cefalo, RC; Fletcher, JR; Lewis, PE; O'Brien, WF; Ramwell, PW | 1 |
| Coceani, F; Olley, PM | 1 |
| Fischer, M | 1 |
| Antonipillai, I; Mulrow, PJ; Tan, SY | 1 |
| Chan, JC | 1 |
| Settipane, GA | 1 |
| Fujimoto, WY; Metz, SA; Robertson, RP | 1 |
| Becker, LC; Jugdutt, BI | 1 |
| Dingfelder, JR | 1 |
| Zawada, ET | 1 |
| Fletcher, JR; Miller, MK; Short, BL | 1 |
| Folts, JD; Gallagher, K; Rowe, GG | 1 |
| Deykin, D; Janson, P; McMahon, L | 1 |
| Gaĭgalene, BA | 1 |
| Edwards, EK; Frost, P; Horwitz, SN | 1 |
| Lindsley, CB | 1 |
| Pang, CY; Sasaki, GH | 1 |
| Phillis, JW; Wu, PH | 1 |
| Curzio, M; Negro, F; Paradisi, L; Parola, M; Torrielli, MV | 1 |
| Aleksandrovskaia, TN; Androsova, SO; Kutirina, IM; Lukovnikova, LP; Nikishova, TA | 1 |
| Beckett, W; Feigen, LP; Kadowitz, PJ; King, LW; Ray, J | 1 |
| Chaudhury, RR; Gupta, U; Malhotra, N; Varma, SK | 1 |
| Boer, P; Mees, EJ; Radó, J; Simatupang, T | 1 |
| Fung, WP; Matz, L; Papadimitriou, JM | 1 |
| Lieb, J | 1 |
| Brennan, M | 1 |
| Massing, GK; Mockridge, PB; Wilkerson, RD | 1 |
| Fudenberg, HH; Jonsson, HT; Smith, CL; Wilson, GB | 1 |
| Khan, MA; Kushner, I; Schoenberg, LM | 1 |
| Brandt, KD; Palmoski, MJ | 1 |
| Galasko, CS; Lacey, E; Rushton, S; Samuel, AW | 1 |
| Engler, C; Seifert, MH | 1 |
| Ban, TA; Buchanan, D; Frolich, JC; Ragheb, M | 1 |
| Hüge, W; Stobbe, H | 1 |
| Locatelli, L; Panerai, AE; Sacerdote, P | 1 |
| Aeberhard, EE; Arabolos, NS; Barrett, CT; Castro, FE; Griscavage, JM; Henderson, SA; Ignarro, LJ | 1 |
| Cabrini, DA; Calixto, JB; Silva, AM | 1 |
| Azzopardi, D; Edwards, AD; Marks, KA; Patel, J; Roberts, I | 1 |
| Katski, W; Toczołowski, J | 1 |
| Chemtob, S; Hanna, N; Lachapelle, P; Orquin, J; Roy, MS; Varma, DR | 1 |
| Chatterjee, S; Johnson, DC | 1 |
| Chemtob, S; Li, DY; Varma, DR | 1 |
| King, RL; Levine, RA; Nandi, J; Wagner, KA | 1 |
| Pettipher, ER; Wimberly, DJ | 1 |
| Flaim, SF; Hazard, DR; Hogan, J; Peters, RM | 1 |
| Fiscus, RR; Han, C; Jones, SB; Wang, X; Yang, L | 1 |
| Goel, A; Raghava, GP; Singh, AM; Varshney, GC | 1 |
| Curi, R; de Bittencourt Júnior, PI; Hirata, MH; Williams, JF; Yano, MM | 1 |
| Rola-Pleszczynski, M; Thivierge, M | 1 |
| Klimes, J; Sedlácek, J; Sochor, J; Zahradnícek, M | 1 |
| Costa, A; Forsling, ML; Grossman, A; Yasin, SA | 1 |
| Baran, H; Hornykiewicz, O; Lassmann, H; Vass, K | 1 |
| Audet, M; Barriault, C; Tuchweber, B; Yousef, IM | 1 |
| Baeyens, W; Donato, MG; Sandra, P; van den Bossche, W | 1 |
| Degiulio, PA; Wagerle, LC | 1 |
| Cirillo, R; Lidbury, PS; Vane, JR | 1 |
| Akarasereenont, P; Flower, RJ; Mitchell, JA; Thiemermann, C; Vane, JR | 1 |
| Häglund, BO; Sundelöf, LO; Upadrashta, SM | 1 |
| House, SD; Slater, C | 1 |
| Howell, TH; Williams, RC | 1 |
| Alfredsson, L; Kaufman, DW; Kelly, JP; Koff, RS; Laszlo, A; Shapiro, S; Sheehan, JE; Wiholm, BE | 1 |
| Arai, I; Futaki, N; Hamasaka, Y; Higuchi, S; Iizuka, H; Otomo, S; Yoshikawa, K | 1 |
| Buxton, DB; Halvorsen, O; Olson, MS; Zhou, W | 1 |
| Chemtob, S; Malcolm, DD; Robillard, JE; Segar, JL | 1 |
| Altman, RD; Banovac, K; Hornicek, FJ; Keer, R; Latta, LL; Renfree, K | 1 |
| Cahill, RJ; Gilvarry, J; O'Morain, CA; Sant, SM | 1 |
| Ferrel, RJ; Jones, DL; Kroenke, K; Landry, FJ; Tomich, DJ | 1 |
| Hempel, SL; Hunninghake, GW; Monick, MM | 1 |
| Mue, S; Ohuchi, K; Watanabe, M; Yamada, M | 1 |
| English, N; Hughes, V; Wolf, CR | 1 |
| Cromlish, W; Ethier, D; Evans, JF; Falgueyret, JP; Francis, DA; Greig, GM; Kargman, S; Kennedy, B; O'Neill, GP; Riendeau, D; Tagari, P; Wong, E; Yergey, JA | 1 |
| Copeland, RA; Covington, M; Davis, JP; Dowling, R; Giannaras, J; Nurnberg, S; Orwat, MJ; Pinto, D; Rider, NL; Trzaskos, JM; Williams, JM | 1 |
| Brant, R; Campbell, NR; Hogan, DB; Jennett, P; MacLeod, N | 1 |
| Haberman, HF; Kumar, JR; Ranadive, NS | 1 |
| Akatsu, T; Consolaro, A; Guimarães, SA; Tago, EM | 1 |
| Khalil, RM | 1 |
| Kliewer, SA; Lehmann, JM; Lenhard, JM; Oliver, BB; Ringold, GM | 1 |
| Furukawa, M; Horie, Y; Nakatsugi, S; Terada, N; Yoshimura, T | 1 |
| Furukawa, M; Nakatsugi, S; Sugimoto, N | 1 |
| Leffler, CW; Parfenova, H | 1 |
| Jansen, JB; Peters, WH; Tiemessen, DM; van Lieshout, EM | 1 |
| Warashina, A | 1 |
| Amano, F; Kawaguchi, M; Takahashi, M; Tanaka, Y | 1 |
| Fox, SM; Johnston, SA | 1 |
| Creten, WL; Follens, I; Hartmann, S; Van Acker, KJ; Van Overmeire, B | 1 |
| Hadházy, P; Kocsis, E; Koltai, MZ; Pogátsa, G; Pósa, I; Rösen, P; Winkler, G | 1 |
| Klimes, J; Sedlácek, J; Sochor, J | 1 |
| Hara, A; Ino, N; Mori, H; Niwa, M; Yoshimi, N | 1 |
| Bell, RL; Hulkower, KI; Otis, ER; Wernimont, AK | 1 |
| Akai, H; Denda, A; Endoh, T; Kitayama, W; Kobayashi, Y; Konishi, Y; Nakae, D; Noguchi, O; Okajima, E; Tang, Q; Tsujiuchi, T; Tsutsumi, M | 1 |
| Bray, M; Fumagalli, M; Lattanzio, M; Mosca, F; Tosetto, C | 1 |
| Serrero, G; Ye, H | 1 |
| Lau, HY; Stenton, GR | 1 |
| Abordo, EA; Bowden, K; Huntington, AP; Powell, SL | 1 |
| Davis, CS; McCaw, R; Robbins, ME; Spector, AA; Vartak, S | 1 |
| Nagai, T; Príborský, J; Takayama, K | 1 |
| Kokoska, ER; Miller, TA; Smith, GS | 1 |
| Gupta, P | 1 |
| Biaggioni, I; Black, BK; Jordan, J; Norman, R; Robertson, D; Shannon, JR | 1 |
| Peters, WH; Roelofs, HM; Tiemessen, DM; Van Lieshout, EM | 1 |
| Palmieri, L; Panicucci, P; Ronca, F; Ronca, G | 1 |
| Agnello, D; Ghezzi, P; Lozza, G; Monopoli, A; Sacco, S; Sottocorno, M; Villa, P | 1 |
| Dendrinou-Samara, C; Ekateriniadou, LV; Kessissoglou, DP; Kortsaris, AH; Kyriakidis, DA; Raptopoulou, CP; Terzis, A; Tsotsou, G | 1 |
| Alpert, D; Schwenger, P; Skolnik, EY; Vilcek, J | 1 |
| Dallob, A; De Lepeleire, I; De Schepper, P; Ehrich, EW; Gertz, BJ; Mehlisch, DR; Porras, A; Riendeau, D; Seibold, JR; Van Hecken, A; Wittreich, J; Yuan, W | 1 |
| Gierse, JK; Isakson, PC; Koboldt, CM; Seibert, K; Walker, MC | 1 |
| Ahmad, M; Li, WQ; Morin, I; Su, S; Zafarullah, M | 1 |
| Brock, RW; Hughson, RL; Naylor, HL; Shoemaker, JK | 1 |
| Bähr, OR; Deininger, M; Gulbins, E; Heneka, M; Meyermann, R; Naumann, U; Roller, A; Streffer, J; Weller, M; Winter, S | 1 |
| Avitsur, R; Weidenfeld, J; Yirmiya, R | 1 |
| Hu, HP; Koorevaar, CT; Lemmens, A; van Kampen, A | 1 |
| Ikeda, M; Koshika, A; Miyajima, M; Okada, J | 1 |
| Langenbach, R; Morham, SG; Young, DA; Zhang, X | 1 |
| Allen, RG; Barrington, KJ; Finer, NN; Henderson, CR; Speziale, MV | 1 |
| Bolle, P; Fidanza, S; Tucci, P | 1 |
| McCarthy, DO | 1 |
| Chiang, N; Clària, J; Gaya, J; Pueyo, G; Romano, M; Serhan, CN; Titos, E | 1 |
| Ohlsson, A | 1 |
| Azzopardi, D; Edwards, AD; Hamilton, P; Patel, J; Roberts, I | 1 |
| Wallace, JL | 1 |
| Schrör, K; Weber, A; Yildirim, H | 1 |
| Ascoli, F; Bari, M; Erba, F; Finazzi-Agrò, A; Fiorucci, L; Maccarrone, M | 1 |
| Bali, M; Baudouin-Legros, M; Brouillard, F; Costa de Beauregard, MA; Cougnon, M; Edelman, A; Labarthe, R; Lipecka, J; Tondelier, D; Torossi, T | 1 |
| Calixto, JB; Cechinel-Filho, V; Vaz, ZR; Yunes, RA; Zunino, L | 1 |
| De Carolis, MP; Delogu, AB; Papacci, P; Piersigilli, F; Polimeni, V; Romagnoli, C; Tortorolo, G; Zecca, E | 1 |
| Deninger, MJ; Schoenwald, RD | 1 |
| SoRelle, R | 1 |
| Degroote, K; Langhendries, JP; Lecoutere, D; Smets, K; Van de Broek, H; Van Overmeire, B; Weyler, J | 1 |
| Clyman, RI | 1 |
| Börjesson, M; Fowler, CJ; Tiger, G | 1 |
| Endo, H; Hayashi, T; Iguchi, A; Nakamura, A; Ogawa, O; Sumi, D; Thakur, NK; Umegaki, H; Yoshimura, J | 1 |
| Bani, D; Ciuffi, M; Failli, P; Franchi-Micheli, S; Mazzetti, L; Zilletti, L | 1 |
| Cotton, RB | 1 |
| Danon, A; Rimon, G; Rosenstock, M; Rubin, M | 1 |
| Cuzzolin, L; Dal Cerè, M; Fanos, V | 1 |
| Casalaz, D | 1 |
| Choi, JC; Hahn, SJ; Jo, YH; Kim, CJ; Kim, MS; Min, DS; Rhie, DJ; Sim, SS; Yoon, SH | 1 |
| Abboud, HE; Bonacchi, A; Efsen, E; Gentilini, P; Laffi, G; Marra, F; Pastacaldi, S; Pinzani, M; Tosti-Guerra, C; Valente, AJ; Wenzel, UO | 1 |
| Mardones, C; Ríos, A; Valcárcel, M | 1 |
| Adamska, E | 1 |
| Abdullah, AS; Al-Hashimi, AH; Jawad, AM | 1 |
| Ouellet, M; Percival, MD | 1 |
| Barbarini, M; Bray, M; Colnaghi, M; Fumagalli, M; Gagliardi, L; Mosca, F; Pugni, L | 1 |
| Hammerman, C; Kaplan, M | 1 |
| Han, S; Purdy, RE; Sangha, DS | 1 |
| Brodskaia, SA; Ivanov, SN; Savenkov, MP | 1 |
| Browning, RA; Burgess, FW | 1 |
| Bulter, T; Das, P; Eriksen, JL; Findlay, KA; Golde, TE; Kang, DE; Koo, EH; Marquez-Sterling, N; Murphy, MP; Pietrzik, CU; Sagi, SA; Smith, TE; Wang, R; Weggen, S | 1 |
| Gomes, BC; Kasof, GM; Liu, D; Lorenzi, MV; Lu, JJ; Mongan, KN; Speer, B | 1 |
| Feller, DR; Jaradat, MS; Noonan, DJ; Phornchirasilp, S; Rangwala, SM; Romstedt, KJ; Shams, G; Sutton, M; Wongsud, B | 1 |
| Aggarwal, R; Bajpai, A; Deorari, AK; Paul, VK | 1 |
| Bakroeva, M; Formanek, M; Knerer, B; Kornfehl, J; Thurnher, D | 1 |
| Klime, J; Kríz, J; Sochor, J | 1 |
| Freeman, ML; Gius, D; Guis, D; Harris, S; Holt, JT; Marnett, LJ; Meredith, MJ; Nguyen, TT; Sekhar, KR; Spitz, DR; Summar, ML | 1 |
| Bettiol, T; Chiandetti, L; Lago, P; Pitassi, I; Saia, OS; Salvadori, S; Vianello, A | 1 |
| Djibril, NM; Fackovcova, D; Kriska, M; Kristova, V; Kurtansky, A | 1 |
| Amit, T; Avramovich, Y; Youdim, MB | 1 |
| Downing, SJ; Leese, HJ; Maguiness, SD; Tay, JI; Watson, A | 1 |
| Sharma, HS; Winkler, T | 1 |
| Bergman, M; Bessler, H; Punsky, I; Sirota, L; Ziyada, S | 1 |
| Davis, P; Roberts, RS; Schmidt, B; Solimano, A; Wright, LL | 1 |
| Burde, T; Rimon, G | 1 |
| Calixto, JB; El Sayah, M | 1 |
| Guignard, JP | 1 |
| Khowsathit, P; Limrungsikul, A; Supapannachart, S | 1 |
| Morley, GM | 1 |
| Andrews, CS; Craig, DQ; Murphy, JR | 1 |
| Hansen, TW | 1 |
| Van Overmeire, B | 1 |
| Brooks, G; Crabbe, MJ; Harper, JV; Shattock, MJ; Wang, Y; Yu, XM | 1 |
| Maliarova, LP; Riabkova, AA; Savel'ev, VS; Shostak, NA | 1 |
| Bennett, P; Pan, H; Sawdy, R; Sullivan, M | 1 |
| Charoenchaitrakoo, KM; Dehghani, F; Foster, NR; Warwick, B | 1 |
| Cowan, A; Raffa, RB; Tallarida, RJ | 1 |
| Itoh, Y; Maiguma, T; Makino, K; Oishi, R; Sendo, T; Teshima, D; Yano, T | 1 |
| Chen, JY; Huang, TC; Lee, HS; Su, CM; Su, PH | 1 |
| Swartz, EN | 1 |
| Chotigeat, U; Jirapapa, K; Layangkool, T | 1 |
| Bradbury, CM; Gius, D; Hunt, CR; Lagunas, L; Laszlo, A | 1 |
| Avery, JK | 1 |
| Hennessy, A; Makris, A; Thornton, C | 1 |
| Chu, SJ; Feng, NH; Lin, HI; Wang, D | 1 |
| Gotoh, T; Hoshino, T; Hwang, HJ; Mima, S; Mizushima, T; Mori, M; Takenaka, H; Tomisato, W; Tsuchiya, T; Tsutsumi, S | 1 |
| Al-Majid, S; Hitt, A; McCarthy, DO; Whitney, P | 1 |
| Chemtob, S; Van Overmeire, B | 1 |
| Lucas, R; Mitchell, JA; Vojnovic, I; Warner, TD | 1 |
| Aranda, JV; Parker, GC; Thomas, RL; Van Overmeire, B | 1 |
| Giagoudakis, G; Markantonis, SL | 1 |
| Distefano, G | 1 |
| Benini, D; Cuzzolin, L; Errico, G; Fanos, V; Verlato, G | 1 |
| Bari, F; Domoki, F; Nagy, K; Temesvári, P | 1 |
| Downing, JE; Ingram, MJ; Madden, JC; Rostron, C | 1 |
| Faggian, D; Favaro, F; Lago, P; Plebani, M; Trevisanuto, D; Vedovato, S; Zanardo, V | 1 |
| Praticò, D; Townsend, KP | 1 |
| Cano Sánchez, A; Carrasco Moreno, JI; Fernández Gilino, C; Gimeno Navarro, A; Gutiérrez Laso, A; Izquierdo Macián, I; Morcillo Sopena, F | 1 |
| Ohlsson, A; Shah, S; Walia, R | 2 |
| Bag, J; Mosser, DD; Wang, Q | 1 |
| Balashov, AM | 1 |
| Albano, RM; Assis, MC; Bozza, PT; Coelho, MG; Gayer, CR; Lopes, UG; Marques, EA; Nascimento, DO; Paiva, DD; Plotkowski, MC; Raymond, B; Saliba, AM; Silva, MC; Touqui, L | 1 |
| Jaillard, S; Larrue, B; Magnenant, E; Rakza, T; Storme, L; Warembourg, H | 1 |
| Jarnagin, K; Kolaja, K; Pearson, CI; Sagartz, J; Tugendreich, S | 1 |
| Mandula, H; Parepally, JM; Smith, QR | 1 |
| Abad-Santos, P; Aranda, JV; Beharry, KD; Gharraee, Z; Hasan, J; Jan, A; Modanlou, HD; Nageotte, S; Sills, JH | 1 |
| Aranda, JV; Thomas, R | 1 |
| Martin, BR; Razdan, RK; Wiley, JL | 1 |
| Bertini, S; Bonardi, S; Coruzzi, G; Giovannini, E; Grandi, D; Menozzi, A; Pozzoli, C; Solenghi, E; Vasina, V | 1 |
| Allegaert, K; Anderson, BJ; Rayyan, M | 1 |
| Bosch, EP; Boulton, P; Dodick, DW; Purdy, RA | 1 |
| Blanzat, M; Bordat, P; Consola, S; Garrigues, JC; Perez, E; Rico-Lattes, I | 1 |
| Alajakku, K; Boldrup, L; Cocco, MT; Fowler, CJ; Holt, S; Onnis, V; Paylor, B; Sundström, A; Vandevoorde, S | 1 |
| Abdel-Meguid, IE; Aly, H; Badrawi, N; Ghawas, M; Hammad, TA; Lotfy, W | 1 |
| Hall, CE; Ingram, MJ; Moss, GP; Zeller, E | 1 |
| Atherton, J; Bauman, J; Kohl, C; Lam, W; Lou, Z; Mutlib, A; Reily, M; Walker, GS | 1 |
| Craig, DQ; Harding, L; Reading, M | 1 |
| Cherif, A; Jabnoun, S; Khrouf, N | 1 |
| Dahlstrom, JE; Falk, MC; Kent, AL; Koina, ME; Maxwell, LE; Willenborg, D | 1 |
| Chen, HH; Chiu, HY; Hsieh, HY; Lin, HC; Su, BH; Tsai, YC | 1 |
| Choi, H; Chung, M; Kim, I; Kim, M; Kim, O; Lee, S; Lim, H; Lim, W; Park, J | 1 |
| Badiee, Z; Fakhraee, SH; Kazemian, M; Kelishadi, R; Mojtahedzadeh, S | 1 |
| Fernández Gilino, C; Gimeno Navarro, A; Gutiérrez Laso, A; Izquierdo Macián, I; Modesto Alapont, V; Morcillo Sopena, F | 1 |
| Abad-Santos, M; Abad-Santos, P; Aranda, JV; Beharry, KD; Gharraee, Z; Hasan, J; Modanlou, HD; Stavitsky, Y | 1 |
| Eling, TE; Kim, JI; Moon, Y; Yang, H | 1 |
| Bag, J; Wang, Q | 1 |
| Czirr, E; Esselmann, H; Leuchtenberger, S; Lichtenthaler, SF; Maler, J; Ness, J; Pietrzik, CU; Weggen, S; Wiltfang, J | 1 |
| Corff, KE; Sekar, KC | 1 |
| Bromiker, R; Hammerman, C; Jacobson, S; Kaplan, M; Nir, A; Schimmel, MS; Shchors, I | 1 |
| Chiozza, L; Faggian, D; Favaro, F; Trevisanuto, D; Vedovato, S; Zanardo, V | 1 |
| Chakraborty, H; Mondal, S; Sarkar, M | 1 |
| Pai, VB; Puthoff, TD; Sakadjian, A | 1 |
| Berns, M; Helfenstein, D; Koehne, P; Obladen, M; Rheinlaender, C; Walch, E | 1 |
| Hayakawa, K; Hiramatsu, N; Kitamura, M; Okamura, M; Paton, AW; Paton, JC; Takano, Y; Yao, J | 1 |
| Asami, M; Fujiwara, J; Kunikane, S; Manabe, S; Matsuda, M; Simazaki, D | 1 |
| Desikan, S; Haddadin, R; Hussain, M; Qian, F; Smith, RL | 1 |
| Cabral Marques, HM; Feio, G; Figueirinhas, JL; Pinto, JF; Salústio, PJ | 1 |
| McCrea, HJ; Ment, LR | 1 |
| Baquero, H; Borbonet, D; Cabañas, F; Fajardo, C; Goldsmit, G; Golombek, SG; Lemus, L; Miura, E; Pellicer, A; Pérez, JM; Rogido, M; Sola, A; van Overmeire, B; Zambosco, G | 1 |
| Imamura, S; Ito, K; Momma, K; Nakanishi, T; Sugiyama, K; Sun, F; Toyoshima, K | 1 |
| Bertram, JF; Dahlstrom, JE; Douglas-Denton, R; Falk, MC; Kent, AL; Koina, ME; Maxwell, LE; Shadbolt, B; Willenborg, D | 1 |
| Collins, C; Henderson, SC; Herrick, B; Klausner, AP; Koo, HP; Miner, AS; Ratz, PH | 1 |
| Choi, KH; Chung, MW; Kim, KB; Kim, SH; Lee, HJ; Oh, HY; Oh, JS; Um, SY | 1 |
| Arakawa, H; Matsuoka, N; Morita, M; Nishimura, S; Osoda, K; Shirai, F; Yamazaki, M | 1 |
| Abad-Santos, M; Abad-Santos, P; Aranda, JV; Beharry, KD; Brock, RS; Gebrekristos, B; Kuniyoshi, K; Modanlou, HD | 1 |
| Bratlid, D; Farstad, T | 1 |
| Allegaert, K | 1 |
| Abraham, RM; Curtis, M; Hooper, DC; Luzi, P; Rafi, MA; Wenger, DA | 1 |
| Bromiker, R; Hammerman, C; Kaplan, M; Nir, A; Schimmel, MS; Shchors, I | 1 |
| Boubred, F; Mercanti, I; Simeoni, U | 1 |
| Aranda, JV; Beharry, KD; Valencia, GB | 1 |
| Bello, R; Birk, E; Hernandez, A; Klinger, G; Linder, N; Pushkov, Y; Rosen, C; Sirota, L | 1 |
| Cotten, CM; Dang, CN; Goldberg, RN; Katakam, LI; Smith, PB | 1 |
| Kock, JL; Kriel, WM; Leeuw, NJ; Ncango, DM; Pohl, CH; Swart, CW; van Wyk, PW | 1 |
| Czernik, C; Helfenstein, D; Koehne, P; Obladen, M; Pees, C; Rheinlaender, C; Walch, E | 1 |
| Benitz, WE | 1 |
| Aronoff, DM; Carlos, D; Faccioli, LH; Lourenço, EV; Machado, ER; Ramos, SG; Silva, EV; Sorgi, CA; Souza, GE; Ueta, MT | 1 |
| Ohlsson, A; Shah, SS; Walia, R | 3 |
| Garg, S; Kurup, B | 1 |
| Abbott, PV; Ashouri, R; Askarifard, S; Nakhaee, N; Pardakhti, A; Parirokh, M; Rekabi, AR | 1 |
| Chen, H; Gan, T; Lv, R; Wei, W; Xia, Z; Yang, F | 1 |
| Attia, J; Craven, PD; Jones, LJ; Thakkinstian, A; Wright, I | 1 |
| Sekar, KC | 1 |
| Cristofoletti, R; Fabricio, AS; Lindsey, CJ; Melo, MC; Soares, DM; Souza, GE; Veiga-Souza, FH | 1 |
| Aperia, A; Casper, C; Li, Y; Marcoux, MO; Plat-Willson, G; Zelenina, M | 1 |
| Brissaud, O; Guichoux, J | 1 |
| Cotten, CM; Ethington, PN; Goldberg, RN; Katakam, L; Smith, PB | 1 |
| Deorari, A; Sasi, A | 1 |
| An, H; Jiang, DM; Luo, XJ; Ou, YS; Quan, ZX; Tan, C; Tang, K | 1 |
| Aschner, M; Gupta, RC; Milatovic, D; Yu, Y; Zaja-Milatovic, S | 1 |
| Kushnir, A; Pinheiro, JM | 1 |
| Fisher, D; Gilpin, CJ; Li, H; Li, S; Mukhopadhyay, D; Wang, H; Xing, B | 1 |
| Ciarmoli, E; Mosca, F; Schena, F | 1 |
| Dani, C | 1 |
| Cheng, KW; Constantinides, PP; Rigas, B; Wong, CC; Xie, G; Zhou, D; Zhu, CH | 1 |
| Unlü, B; van Leeuwen, JS; Vermeulen, NP; Vos, JC | 1 |
| Junyaprasert, VB; Kreuter, J; Sripha, K; Suksiriworapong, J | 1 |
| Dessì, A; Fanos, V; Marcialis, MA; Pusceddu, M | 1 |
| Adrouche-Amrani, L; Gluck, KM; Green, RS; Lin, J | 1 |
| Fuller, MP; Gillam-Krakauer, M; Johnston, PG; Reese, J | 1 |
| Bührer, C; Neumann, R; Schulzke, SM | 1 |
| Bin-Nun, A; Hammerman, C; Kaplan, M | 1 |
| Walther, FJ | 1 |
| Cantwell, MM; Hughes, CM; Murray, LJ; Parsons, C; Reid, J | 1 |
| Bhatt, M; Mehta, R; Petrova, A | 1 |
| Agarwal, G; Maheshwari, A; Mezu-Ndubuisi, OJ; Ohler, KH; Pham, JT; Raghavan, A | 1 |
| Boubred, F; Buffat, C; Fayol, L; Grandvuillemin, I; Ligi, I; Mercanti, I; Millet, V; Simeoni, U | 1 |
| Forbes, RT; Gray, J; Hulse, WL | 1 |
| An, H; Jiang, D; Luo, X; Ou, Y; Quan, Z; Tan, C; Tang, K | 1 |
| Aliaga, ME; Lopez-Alarcón, C; Sandoval-Acuña, C; Speisky, H | 1 |
| Pacifici, GM | 2 |
| Dilmen, U; Erdeve, O; Ozdemir, R; Yurttutan, S | 1 |
| Häussinger, D; Kircheis, G | 1 |
| Ertan, M; Kazkayası, I; Okay, G; Oztürk, Eİ; Sarıgöl, D; Tel, BC; Tozkoparan, B; Uzgören-Baran, A | 1 |
| Bührer, C; Dame, C; Felderhoff-Müser, U; Hansmann, G; Horn, PA; Hüning, B; Koehne, P; Metze, BC; Sallmon, H; Stein, A; Weber, SC | 1 |
| Chai, MZ; Flanagan, JU; Squire, CJ; Teague, RM; Turnbull, AP; Yosaatmadja, Y | 1 |
| Harirforoosh, S; Pettit, WL; Wyatt, JE | 1 |
| Heo, MJ; Lee, OS; Lim, SC | 1 |
| Laraba-Djebari, F; Sebia-Amrane, F | 1 |
| Chen, HN; Hsiao, CC; Lee, CH; Lee, ML; Tsao, LY | 1 |
| Cheng, GQ; Zhang, CC | 1 |
| Aoyama, M; Asai, H; Asai, K; Kakita, H; Nagaya, Y; Saitoh, S | 1 |
| Bali, V; Harabor, A; Kamaluddeen, M; Sivanandan, S; Soraisham, AS | 1 |
| Bebawy, M; Haghi, M; Mamlouk, M; Mamlouk, S; Mulay, V; Traini, D; Young, PM | 1 |
| Attridge, JT; Carey, WA; Clyman, R; Couser, R; Derrick, M; Fujii, A; Gillam-Krakauer, M; Hassinger, DC; Jegatheesan, P; Jhaveri, N; Mammel, M; Mulrooney, N; Polin, R; Porta, N; Reese, J; Sanocka, U; Swanson, JR; Walsh, M; Wickremasinghe, A; Yanowitz, TD | 1 |
| Ahmad, Z; Bouropoulos, N; Fatouros, DG; Karavasili, C; Kontopoulou, I; Rehman, IU; Smith, A; van der Merwe, SM | 1 |
| Carey, WA; Clyman, R; Cochran, CM; Fabio, A; Fujii, A; Gillam-Krakauer, M; Jegatheesan, P; Lau, J; Reese, J; Tran, VT; Walsh, M; Yanowitz, TD | 1 |
| Bueters, RR; Klaasen, A; Schreuder, MF; van den Heuvel, LP | 1 |
| Agarwal, S; Anand, P; Dubey, NK; Dudeja, A; Maria, A; Yadav, DK; Yadav, S | 1 |
| Coceani, F | 1 |
| Chan, NM; Kwan, KF; Law, CW | 1 |
| Du, L; Jin, Y; Li, M; Liu, B; Zhu, W; Zuo, J | 1 |
| Hashimoto, T; Ono, K; Satoh, T | 1 |
| Kimura, S; Nagane, K; Ogawa, N; Ukai, K; Yamamoto, H | 1 |
| Alabed, S; Burls, A; Cabello, JB; Irving, GJ; Qintar, M | 1 |
| Bertram, JF; Cullen-McEwen, LA; Dahlstrom, JE; Falk, MC; Gubhaju, L; Kent, AL; Koina, ME; Lynnhtun, J; Shadbolt, B | 1 |
| Amidon, GE; Amidon, GL; Krieg, BJ; Taghavi, SM | 1 |
| Danielsen, B; Dueñas, GV; Durand, DJ; Lee, HC; Powers, RJ | 1 |
| Ambadwar, PB; Bird, TM; ElHassan, NO; Jaquiss, RD; Kaiser, JR; King, AJ; Robbins, JM | 1 |
| Erdeve, O; Oncel, MY | 1 |
| Malikiwi, A; Roufaeil, C; Sehgal, A; Tan, K | 1 |
| Bonamy, AK; Gudmundsdottir, A; Håkansson, S; Johansson, S; Källen, K; Norman, M | 2 |
| Menon, D; Nair, S; Narayanan, D | 1 |
| Chessell, L; de Boer, C; Dutta, S; Fusch, C; Gaal, B; Gardner, VA; Hjartarson, A; Janes, M; McDonald, K; Purcha, M; Shahid, S; Singh, B; Watson, J; Wilson, J | 1 |
| Cheng, F; Deng, X; Huang, J; Jiang, J; Lu, W; Shen, X; Tang, Y; Xu, Z; Zhang, C; Zou, S | 1 |
| Aranda, JV; Bany-Mohammed, F; Beharry, KD; Inayat, M; Jacinto, J; Tay, C; Valencia, A | 1 |
| Meyer, S | 1 |
| Ohlsson, A; Shah, PS | 3 |
| Daniel, S; Koren, G; Levy, A; Lunenfeld, E | 1 |
| Olsson, KW; Sindelar, R | 1 |
| Hsu, JR; Noel, SP; Rathbone, CR; Rivera, JC; Wenke, JC | 1 |
| Coboeken, K; Ince, I; Meyer, M; Schmidt, S; Schnizler, K; Somani, AA; Thelen, K; Trame, MN; Willmann, S; Zheng, S | 1 |
| Clark, RH; Gulack, BC; Hornik, CP; Laughon, MM; Sankar, MN; Smith, PB | 1 |
| Amabilino, DB; Amirthalingam, E; Andrade, B; Calpena, AC; Garduño-Ramírez, ML; Halbaut, L; Limón, D; Pérez-García, L; Rodrigues, M | 1 |
| Klingler, FM; Merk, D; Proschak, E; Schmidt, J; Schubert-Zsilavecz, M; Steinhilber, D | 1 |
| Matteson, EL; Thongprayoon, C; Ungprasert, P | 1 |
| Doods, H; Gould, SA; Lamla, T; Pekcec, A | 1 |
| Hussain, N; Lainwala, S | 1 |
| Aho, J; Baldursdottir, S; Botker, J; Edinger, M; Rantanen, J | 1 |
| Deyo, RA; Enthoven, WT; Koes, BW; Roelofs, PD; van Tulder, MW | 1 |
| Hansmann, G; Koehne, P; Sallmon, H | 1 |
| Bapat, RV; Klebanoff, MA; Newman, TB; Reagan, PB; Slaughter, JL | 1 |
| Jang, IS; Nakamura, M | 1 |
| Agarwal, R; Sivanandan, S | 1 |
| Vettukattil, JJ | 1 |
| Baral, VR; Tan, ZH | 1 |
| McPherson, CC; Rostas, SE | 1 |
| Haw, MP | 1 |
| Aune, D; Florez, ID; Mbuagbaw, L; Mitra, S; Tamayo, ME; Thabane, L; Veroniki, AA | 1 |
| Choi, KH; Chung, MW; Lee, HJ; Park, JH; Um, SY | 1 |
| Jaraba Caballero, MP; Parraga Quiles, MJ; Rodríguez Benítez, MV; Ruiz González, MD; Tofé Valera, I | 1 |
| Brownell, EA; Campbell, BT; Hagadorn, JI; Herbst, KW; Johnson, KR; Lainwala, S; Trzaski, JM | 1 |
| Bancalari, E | 1 |
| Keim-Malpass, J; Prescott, S | 1 |
| Chen, CM; Florens, A; Huang, FK; Kuo, YT; Lin, YJ; Rehan, VK; Tsai, ML; Wu, SY; Yeh, TF | 1 |
| Leão, RM; Zugaib, J | 1 |
| El Amrousy, D; El-Mahdy, H; El-Mashad, AE; Elgendy, M | 1 |
| Kramulová, B; Marsik, P; Rezek, J; Tauchen, J; Vaněk, T; Židková, M | 1 |
| Bancalari, E; Jain, D | 1 |
| Ahmadi, S; Farahani, Z; Kalani, M; Khalesi, N; Shariat, M | 1 |
| Lavín, P; López, M; Miranda, J; Rincón, Y; Salas, R | 1 |
| Gould, JB; Lee, HC; Ngo, S; Profit, J | 1 |
| Bixler, GM; Clark, RH; Powers, GC; Tolia, VN; Walker, MW | 1 |
| Bell, EF; Bethany Ball, M; Boghossian, NS; Brumbaugh, JE; Dagle, JM; Das, A; Do, BT; Sanchez, PJ; Shankaran, S; Stoll, BJ; Vohr, BR; Wyckoff, MH | 1 |
| Benitz, WE; Bhombal, S | 1 |
| Laitinen, R; Lerminiaux, L; Ojarinta, R | 1 |
| Akanbi, S; Gratopp, A; Koehne, P; Rheinländer, C; Sallmon, H; Weber, SC | 1 |
| Bochmann, ES; Gryczke, A; Steffens, KE; Wagner, KG | 1 |
| Du, J; Hu, Y; Jiang, Y; Jin, H | 1 |
| Kannankeril, PJ; Lewis, TR; Reese, J; Shelton, EL; Van Driest, SL | 1 |
| Gupta, S; Wyllie, JP | 1 |
| Florez, ID; Mbuagbaw, L; Mitra, S; Sadeghirad, B; Tamayo, ME; Thabane, L; Vanniyasingam, T; Veroniki, AA; Zea, AM; Zhang, Y | 1 |
| Azam, MW; Khan, AU; Khan, SN; Maryam, L; Sharma, A | 1 |
| Brede, K; Genina, N; Hempel, NJ; Knopp, MM; Löbmann, K; Olesen, NE | 1 |
| Brown, LD; Stremming, JE; Wright, CJ | 1 |
| Nichols, CG; Shelton, EL; Singh, GK | 1 |
| Jatuwattana, C; Khuwuthyakorn, V; Silvilairat, S; Tantiprapha, W | 1 |
| Carnielli, VP; Cogo, PE; Colaneri, M; Pedini, A; Pozzi, M; Romagnoli, V; Santoni, M; Scutti, G | 1 |
| Abou-Setta, AM; Dingwall, O; Elsayed, YN; Farooqui, MA; Jeyaraman, MM; Rabbani, R; Tagin, M; Zarychanski, R | 1 |
| Korhonen, O; Laitinen, R; Ojarinta, R; Saarinen, J; Strachan, CJ | 1 |
| Casey, PH; Collins, RT; Gossett, JM; Lyle, RE; Rettiganti, M; Robbins, JM | 1 |
| Aucott, SW; Bulbul, A; Carey, WA; Clyman, RI; Derrick, M; Dong, L; Erdeve, O; Farooqi, A; Fernandez, E; Håkansson, S; Hassinger, DC; Hayashi, M; Heuchan, AM; Kaempf, J; Katheria, A; Leone, T; Liebowitz, M; Lindqvist, J; Nelson, K; Perez, J; Sankar, M; Sauberan, J; Serize, A; Singh, J; Wickremasinghe, A | 1 |
| Ferguson, JM | 1 |
| Bussmann, N; EL-Khuffash, A | 1 |
| Fujioka, A; Imamura, K; Imanaka, H; Ishida, N; Matsuura, T; Okamoto, T; Sekitoh, T; Takeda, K; Yamamoto, K | 1 |
| Kaur, S; Soraisham, AS; Stritzke, A | 1 |
| Kumar, J; Yadav, A | 1 |
| Aucott, SW; Bulbul, A; Carey, WA; Clyman, RI; Derrick, M; Dong, L; Erdeve, O; Farooqi, A; Håkansson, S; Hassinger, DC; Hayashi, M; Heuchan, AM; Kaempf, J; Katheria, A; Kimball, A; Leone, T; Liebowitz, M; Lindqvist, J; Nelson, K; Perez, J; Sankar, M; Sauberan, J; Serize, A; Singh, J; Wickremasinghe, A; Wolf, IS | 1 |
| Allegaert, K; Cristea, S; Falcao, AC; Falcao, F; Knibbe, CAJ; Krekels, EHJ; Silva, R; Smits, A | 1 |
| Aydin, T; Bode, C; Bührer, C; Endesfelder, S; Hort, S; Klippstein, T; Koehne, P; Kubinski, A; Sallmon, H | 1 |
| Khuwuthyakorn, V; Silvilairat, S; Tantiprabha, W | 1 |
| Hajhashemi, V; Mesripour, A; Shahnooshi, S | 1 |
| Mamontov, E; Sharma, VK; Tyagi, M | 1 |
| Brinkmann, J; Huxoll, F; Luebbert, C; Sadowski, G | 1 |
| Matsuda, A; Nishizaki, N; Obinata, K; Shimizu, T; Watanabe, A; Yoneyama, T | 1 |
| Ei-Saie, A; Maheshwari, A; Neu, J; Pammi, M; Xiong, T | 1 |
| Aceti, A; Beghetti, I; Corvaglia, L; Faldella, G; Galletti, S; Martini, S | 1 |
| Ohlsson, A; Shah, SS | 1 |
| Adams, M; Bassler, D; Hakansson, S; Helenius, K; Isayama, T; Jain, A; Kusuda, S; Lee, SK; Lehtonen, L; Norman, M; Reichman, B; Shah, PS; Yang, J | 1 |
| Brinkmann, J; Luebbert, C; Rest, F; Sadowski, G | 1 |
| Davidson, JM; Ferguson, J; Ivey, E; Philip, R; Talati, AJ; Weems, MF | 1 |
| Andrews, GP; Jacobs, E; Jones, DS; McCoy, CP; Tian, Y; Wu, H | 1 |
| Guo, H; Huang, Y; Lin, HC; Liu, H; Peng, H; Shen, X; Yao, S; Zhou, M; Zhou, P | 1 |
| Bonsante, F; Gambacorta, S; Gouyon, B; Gouyon, JB; Iacobelli, S; Laforgia, N; Lorrain, S | 1 |
| Akerman, S; Andreou, AP; Goadsby, PJ; Hoffmann, J; Holland, PR; Summ, O | 1 |
| Böckenholt, K; Erdmann, H; Göpel, W; Härtel, C; Herting, E; Hoppenz, M; Marissen, J; Rausch, TK | 1 |
| Beroukhim, RS; Cumbermack, KM; Ferrer, Q; Freud, LR; Glickstein, JS; LaFranchi, T; Makhoul, M; Morris, SA; Pedra, SR; Phoon, CK; Sun, HY; Tworetzky, W; Wilkins-Haug, LE | 1 |
| Dey, A; Jain, A; Louis, D | 1 |
| Alves, RR; Castelo, RJS; Faim, DRO; Francisco, ASS; Pires, AMGS; Tiago, JAM | 1 |
| Ishiguro, A; Kabe, K; Kanai, M; Masutani, S; Matsumura, S; Namba, F; Oshima, A | 1 |
| Disher, T; Mitra, S; Scrivens, A; von Kursell, AM | 1 |
| Aikio, O; Hallman, M; Rozé, JC; Treluyer, JM | 1 |
| Breatnach, CR; Bussmann, N; Cleary, B; El-Khuffash, A; Franklin, O; McCallion, N; McNamara, PJ; Smith, A | 1 |
| Amin, S; Manalastas, M; Nicoski, P; Weiss, MG; Zaheer, F | 1 |
| Abou Mehrem, A; Adie, M; Alvaro, R; Ben Fadel, N; Bhattacharya, S; Bodani, J; Canning, R; Dorling, J; Drolet, C; Gardner, CE; Hatfield, T; Hyderi, A; Jain, A; Jasani, B; Kanungo, J; Khurshid, F; Kumaran, K; Lapointe, A; Louis, D; Mitra, S; Morin, A; Shah, P; Soraisham, A; Stavel, M; Ting, JY; Weisz, D; Ye, XY | 1 |
| Iwersen-Bergmann, S; May, A; Mehnert, J; Möller, M; Schröder, C | 1 |
| Bäumer, S; Eckardt, L; Ellermann, C; Fehr, M; Frommeyer, G; Leitz, PR; Wegner, F; Willy, K; Wolfes, J | 1 |
| Anson, BJ; Bonham, C; Brito-Sierra, CA; Ghosh, AK; Hattori, SI; Kovela, S; Kuhn, R; Lendy, EK; Mesecar, AD; Mitsuya, H; Shahabi, D; Sirohi, D; Yadav, M | 1 |
| Chatziravdeli, VI; Dardiotis, E; Doxani, C; Katsaras, DN; Katsaras, GN; Mitsiakos, G; Papavasileiou, GN; Stefanidis, I; Touloupaki, M | 1 |
| Vidavalur, R | 1 |
| de Boode, WP; El-Khuffash, A; Hundscheid, T; McNamara, PJ | 1 |
| Barlow, DJ; Ishkhanyan, H; Lawrence, MJ; Lorenz, CD; Rhys, NH | 1 |
| Abdaljalil, H; Abu-Omar, R; Bin-Nun, A; Hammerman, C; Kasirer, Y; Mimouni, F; Nitzan, I; Schorrs, I | 1 |
| Jain, A; Jasani, B; Shahroor, M; Weisz, D; Yeung, T | 1 |
| Aldrete, MC; Guerrero-González, M; Meraz-Rios, MA | 1 |
| Du, G; Fang, Z; Gong, N; Lu, Y; Xing, C; Xing, W; Yu, H; Zhang, B | 1 |
| Aziz, KB; Harnett, S; Hudak, ML; Makker, K; Shah, SD; Zhang, M | 1 |
| Al-Turkait, A; Choonara, I; Ojha, S; Szatkowski, L | 1 |
| Manalastas, M; Nnamdi-Nwosu, O; Okwundu, C; Olowoyeye, A | 1 |
| Avino, D; de Baat, T; De Bisschop, B; de Boode, WP; de Vries, WB; Derriks, F; Dijk, PH; Dijkman, KP; Donders, R; Henriksen, TB; Hocq, C; Hundscheid, T; Kooi, EMW; Kroon, AA; Kyng, KJ; Meeus, M; Mulder, AL; Mulder-de Tollenaer, SM; Nuytemans, DHGM; Onland, W; van Kaam, AH; Van Overmeire, B; Vijlbrief, DC; Villamor, E; Visser, R; Zecic, A | 1 |
| Engbers, AGJ; Flint, RB; Knibbe, CAJ; Pfister, M; Samiee-Zafarghandy, S; Simons, SHP; Smit, C; van den Anker, JN; van Donge, T | 1 |
| Jasani, B; Mitra, S; Shah, PS | 1 |
| Kobayashi, H; Miyosawa, Y; Motoki, N; Utsumi, M; Yamazaki, S; Yokota, S | 1 |
| Ibara, S; Ieiri, S; Ikee, T; Ikoma, S; Kawano, M; Kawano, T; Machigashira, S; Masuya, R; Matsukubo, M; Murakami, M; Muto, M; Nakame, K; Noguchi, H; Sugita, K; Torikai, M | 1 |
| Abdelnaser, A; Bekheit, MS; Bokhtia, RM; Dawood, AS; Ghanim, AM; Girgis, AS; Nasr, S; Panda, SS; Said, MF; Samir, N; Sharma, H; Sharma, SK; Wade, M | 1 |
| Campbell-Yeo, M; Dorling, J; Hatfield, T; Johnston, BC; Mitra, S | 1 |
| Borges-Luján, M; González-Luis, G; Villamor, E | 1 |
| Jain, A; Jasani, B; Reese, J; Weisz, DE | 1 |
| Delaney, CA; Sallmon, H | 1 |
| Hua, L; Jia, X; Lou, X; Xu, L; Zhang, Z; Zhao, M | 1 |
| Fukuoka, N; Honda, M; Kawada, K; Kikuchi, K; Mikami, M; Motojima, Y; Namba, F; Ogawa, K; Sakatani, S; Sako, M; Ueda, K | 1 |
| de Boode, WP; Mitra, S; Shah, PS; Weisz, DE | 1 |
| Al-Lohedan, HA; Al-Sanea, ASS; Ali, MS; Jain, M; Muthukumaran, J; Tariq, M | 1 |
| Abounahia, F; Abushanab, D; Al-Badriyeh, D; Al-Shaibi, S; Awaisu, A | 1 |
| Jensen, EA; McCulley, DJ; Mitra, S; Wright, CJ | 1 |
| Ahmed, A; Cheema, HA; Dani, SS; Ghelani, SJ; Hayat, T; Ijaz, SH; Kulkarni, A; Majeed, Z; Minhas, AMK; Shahid, A; Tariq, MH; Titus, A | 1 |
| Bell, A; Eschweiler, J; Hildebrand, F; Maffulli, N; Migliorini, F; Schneider, J | 1 |
121 review(s) available for ibuprofen and indomethacin
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship | 2016 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Quinoxaline: An insight into the recent pharmacological advances.
Topics: Animals; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents; Antihypertensive Agents; Antineoplastic Agents; Humans; Quinoxalines | 2018 |
Thieno[2,3-d]pyrimidine as a promising scaffold in medicinal chemistry: Recent advances.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Chemistry, Pharmaceutical; Humans; Inflammation; Neoplasms; Pyrimidines; Structure-Activity Relationship | 2019 |
Contemporary advances of cyclic molecules proposed for inflammation.
Topics: Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Humans; Inflammation; Molecular Structure; Structure-Activity Relationship | 2021 |
Antiinflammatory drugs.
Topics: Adult; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Benzylidene Compounds; Child; Drug Evaluation; Female; Humans; Ibuprofen; Indenes; Indomethacin; Ketoprofen; Mefenamic Acid; Naproxen; Phenylacetates; Phenylbutazone; Pregnancy; Pregnancy Complications; Propionates; Tolmetin | 1977 |
Drug therapy in rheumatic diseases.
Topics: Acetaminophen; Adrenal Cortex Hormones; Antimalarials; Aspirin; Colchicine; Fenoprofen; Gold; Humans; Ibuprofen; Indomethacin; Levamisole; Naproxen; Penicillamine; Phenylbutazone; Rheumatic Diseases; Tolmetin | 1977 |
[Drug therapy of ankylosing spondyloarthritis (Bechterew's disease)].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Apazone; Butadienes; Cyclophosphamide; Diclofenac; Drug Combinations; Drug Evaluation; Glycolates; Gold; Humans; Ibuprofen; Indomethacin; Ketoprofen; Levamisole; Naproxen; Oxyphenbutazone; Phenylbutazone; Salicylates; Spondylitis, Ankylosing; Sulindac | 1978 |
Treatment of rheumatoid arthritis: a review including newer and experimental anti-inflammatory agents.
Topics: Activities of Daily Living; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin; Aurothioglucose; Fenoprofen; Humans; Ibuprofen; Immunosuppressive Agents; Indomethacin; Naproxen; Oxyphenbutazone; Penicillamine; Phenylbutazone; Physical Therapy Modalities; Tolmetin | 1976 |
Rheumatoid arthritis: an overview.
Topics: Adult; Arthritis; Arthritis, Reactive; Arthritis, Rheumatoid; Aspirin; Diagnosis, Differential; Female; Gold; Humans; Ibuprofen; Indomethacin; Lupus Erythematosus, Systemic; Male; Osteoarthritis; Phenylbutazone; Radiography | 1976 |
Myocardial infarct expansion during indomethacin or ibuprofen therapy for symptomatic post infarction pericarditis. Influence of other pharmacologic agents during early remodelling.
Topics: Adrenergic alpha-Antagonists; Drug Therapy, Combination; Echocardiography; Ibuprofen; Indomethacin; Myocardial Infarction; Nitroglycerin; Pericarditis; Prednisone; Prospective Studies; Time Factors | 1989 |
Non-steroidal and analgesic therapy in the elderly.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Apazone; Aspirin; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Diclofenac; Drug Hypersensitivity; Gastrointestinal Diseases; Hematologic Diseases; Humans; Ibuprofen; Indomethacin; Ketoprofen; Kidney Diseases; Kinetics; Naproxen; Phenylbutazone; Piroxicam; Salicylates; Thiazines | 1986 |
Cutaneous reactions to nonsteroidal anti-inflammatory drugs. A review.
Topics: Acetates; Anti-Inflammatory Agents; Aspirin; Drug Eruptions; Humans; Ibuprofen; Indomethacin; ortho-Aminobenzoates; Piroxicam; Propionates; Pruritus; Pyrazoles; Pyrazolones; Salicylates; Skin; Skin Diseases; Stevens-Johnson Syndrome; Thiazines | 1985 |
[Dysmenorrhea in the female adolescent. Clinical, biological and therapeutic data].
Topics: Adolescent; Dinoprost; Dysmenorrhea; Female; France; Humans; Ibuprofen; Indomethacin; ortho-Aminobenzoates; Prostaglandin Antagonists; Prostaglandins F; United States | 1986 |
Metabolites of arachidonic acid in experimental lung vascular injury.
Topics: Animals; Arachidonic Acids; Endotoxins; Humans; Ibuprofen; Imidazoles; Indomethacin; Lung; Lung Injury; Lymph; Meclofenamic Acid; Methylprednisolone; Sheep | 1985 |
Rare adverse reactions to nonsteroidal antiinflammatory drugs (3).
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Chemical and Drug Induced Liver Injury; Colitis; Digestive System; Esophagus; Female; Humans; Ibuprofen; Indomethacin; Liver; Male; Middle Aged; Pancreatitis; Phenylbutazone; Propionates; Sialadenitis | 1985 |
Prostaglandins and the regulation of renal circulation and function.
Topics: Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Body Water; Glomerular Filtration Rate; Humans; Ibuprofen; Indomethacin; Kidney; Liver Cirrhosis, Alcoholic; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Regional Blood Flow; Vasodilation | 1982 |
Prostaglandins and nonsteroidal antiinflammatory drugs in dysmenorrhea.
Topics: Anti-Inflammatory Agents; Aspirin; Contraceptives, Oral; Dysmenorrhea; Female; Humans; Ibuprofen; Indomethacin; Naproxen; ortho-Aminobenzoates; Phenylpropionates; Prostaglandins | 1983 |
Clinical use of tolmetin sodium in patients with ankylosing spondylitis: a review.
Topics: Clinical Trials as Topic; Double-Blind Method; Humans; Ibuprofen; Indomethacin; Pyrroles; Spondylitis, Ankylosing; Tolmetin | 1983 |
Non-steroidal anti-inflammatory drugs (NSAID'S) as analgesics in dentistry - a review.
Topics: Analgesics; Anti-Inflammatory Agents; Aspirin; Dental Care; Diflunisal; Humans; Ibuprofen; Indomethacin; Ketoprofen; Oxyphenbutazone; Pain, Postoperative; Phenylbutazone | 1983 |
Review of ibuprofen for osteoarthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Meclofenamic Acid; Naproxen; Osteoarthritis; Phenylbutazone; Sulindac; Tolmetin | 1984 |
Update on ibuprofen for rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Piroxicam; Sulindac; Thiazines; Tolmetin | 1984 |
Mechanisms of action: aspirin.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Endothelium; Humans; Ibuprofen; In Vitro Techniques; Indomethacin; Salicylates; Salicylic Acid; Thromboxanes | 1983 |
Mechanism of action of nonsteroidal anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Arthritis, Rheumatoid; Carbazoles; Cell Movement; Cyclooxygenase Inhibitors; Gastritis; Humans; Ibuprofen; Immunoglobulin M; Indomethacin; Lymphocytes; Neutrophils; Piroxicam; Prostaglandin Antagonists; Prostaglandins E; Rheumatoid Factor; Thiazines | 1984 |
Practical therapeutics: the newer nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Arthritis; Aspirin; Diclofenac; Humans; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone; Phenylbutyrates; Piroxicam; Propionates; Sulindac; Thiazines | 1982 |
Diclofenac sodium: a review of its pharmacological properties and therapeutic use in rheumatic diseases and pain of varying origin.
Topics: Adult; Animals; Arthritis, Rheumatoid; Aspirin; Cyclooxygenase Inhibitors; Diclofenac; Drug Interactions; Female; Gastric Mucosa; Gout; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Osteoarthritis; Pain; Phenylacetates; Platelet Aggregation; Rheumatic Diseases; Spondylitis, Ankylosing; Ulcer | 1980 |
Anti-inflammatory agents as inhibitors of prostaglandin synthesis in man.
Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Drug Interactions; Female; Humans; Ibuprofen; Indomethacin; Inflammation; Kinetics; Male; Prostaglandin Antagonists; Prostaglandins; Prostaglandins E; Prostaglandins F; Salicylates; Sex Factors | 1981 |
Current status of the etiology and management of dysmenorrhea in adolescence.
Topics: Adolescent; Aspirin; Contraceptives, Oral; Cyclooxygenase Inhibitors; Dysmenorrhea; Female; Humans; Ibuprofen; Indomethacin; Naproxen; ortho-Aminobenzoates; Ovulation; Prostaglandin Antagonists; Prostaglandins; Uterine Contraction | 1982 |
Role of prostaglandins, prostacyclin, and thromboxanes in the control of prenatal patency and postnatal closure of the ductus arteriosus.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Ductus Arteriosus; Ductus Arteriosus, Patent; Epoprostenol; Female; Ibuprofen; Indomethacin; Labor, Obstetric; Oxygen; Pregnancy; Prostaglandins; Prostaglandins E; Thromboxanes | 1980 |
[Piroxicam--a step forward in the treatment of rheumatism].
Topics: Anti-Inflammatory Agents; Arthritis; Humans; Ibuprofen; Indomethacin; Piroxicam; Pyridines; Rheumatic Diseases; Spondylitis, Ankylosing; Thiazines | 1980 |
Bartter's syndrome.
Topics: Adolescent; Adrenalectomy; Bartter Syndrome; Child; Child, Preschool; Diagnosis, Differential; Female; Growth Disorders; Humans; Hyperaldosteronism; Hypokalemia; Ibuprofen; Indomethacin; Kidney; Male; Potassium; Prognosis | 1980 |
Adverse reactions of aspirin and related drugs.
Topics: Aspirin; Bronchial Spasm; Drug Hypersensitivity; Humans; Ibuprofen; Indomethacin; Prostaglandins; Urticaria | 1981 |
Prostaglandin inhibition and myocardial infarct size.
Topics: Acute Disease; Animals; Aspirin; Coronary Disease; Humans; Ibuprofen; Indomethacin; Models, Biological; Myocardial Infarction; Prognosis; Prostaglandin Antagonists; Prostaglandins | 1981 |
Primary dysmenorrhea treatment with prostaglandin inhibitors: a review.
Topics: Adolescent; Adult; Dysmenorrhea; Female; Humans; Ibuprofen; Indomethacin; Middle Aged; Naproxen; ortho-Aminobenzoates; Phenylbutazone; Prostaglandin Antagonists | 1981 |
Renal consequences of nonsteroidal antiinflammatory drugs.
Topics: Acidosis; Acute Kidney Injury; Aged; Anti-Inflammatory Agents; Bartter Syndrome; Female; Humans; Hyponatremia; Hypotension, Orthostatic; Ibuprofen; Indomethacin; Kidney; Kidney Failure, Chronic; Lupus Erythematosus, Systemic; Nephrotic Syndrome; Prostaglandin Antagonists; Sodium; Vasopressins | 1982 |
Nonsteroidal antiinflammatory drugs as inhibitors of periodontal disease progression.
Topics: Alveolar Bone Loss; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Resorption; Flurbiprofen; Humans; Ibuprofen; Indomethacin; Inflammation; Periodontal Diseases; Prostaglandin Antagonists; Prostaglandins | 1993 |
Use of carprofen for the treatment of pain and inflammation in dogs.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carbazoles; Clonixin; Cyclooxygenase Inhibitors; Dog Diseases; Dogs; Ibuprofen; Indomethacin; Ketoprofen; Meclofenamic Acid; Meloxicam; Naproxen; Osteoarthritis; Pain; Phenylbutazone; Piroxicam; Thiazines; Thiazoles | 1997 |
Distribution and expression of cyclooxygenase (COX) isoenzymes, their physiological roles, and the categorization of nonsteroidal anti-inflammatory drugs (NSAIDs).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Controlled Clinical Trials as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Etodolac; Gene Expression; Humans; Ibuprofen; Indomethacin; Isoenzymes; Meloxicam; Membrane Proteins; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Thiazines; Thiazoles | 1999 |
NSAID-induced nephrotoxicity from the fetus to the child.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Ductus Arteriosus, Patent; Female; Fetus; Humans; Ibuprofen; Indomethacin; Infant; Infant, Newborn; Pregnancy; Prenatal Exposure Delayed Effects; Prostaglandins; Renal Insufficiency | 2001 |
[Ibuprofen--a new application for pharmacological closure of patent ductus arteriosus in preterm infants. Preliminary report].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bronchopulmonary Dysplasia; Clinical Trials as Topic; Ductus Arteriosus, Patent; Enterocolitis, Necrotizing; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Treatment Outcome | 2000 |
[Cerebral oxygenation and near-infrared rays spectrophotometry].
Topics: Blood Transfusion; Brain; Catheterization; Cerebrovascular Circulation; Hemodynamics; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Oxygen; Phlebotomy; Pulmonary Surfactants; Spectroscopy, Near-Infrared; Suction; Umbilicus | 2000 |
Comparative tolerability of pharmacological treatments for patent ductus arteriosus.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature | 2001 |
Patent ductus arteriosus in preterm neonates.
Topics: Cyclooxygenase Inhibitors; Diagnosis, Differential; Ductus Arteriosus, Patent; Echocardiography; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Water-Electrolyte Balance | 2001 |
The use of ibuprofen in neonates in the treatment of patent ductus arteriosus.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Treatment Outcome | 2003 |
Is indomethacin or ibuprofen better for medical closure of the patent ductus arteriosus?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Agents; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn | 2003 |
The pharmacologic closure of the patent ductus arteriosus.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Nitric Oxide; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Receptors, Prostaglandin | 2005 |
A meta-analysis of ibuprofen versus indomethacin for closure of patent ductus arteriosus.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Creatinine; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Oxygen Inhalation Therapy; Randomized Controlled Trials as Topic; Urination | 2005 |
[The pharmacological manipulation of Botallo's duct in the duct-dependent congenital cardiopathies and in the preterm infants with respiratory distress. A review and personal findings].
Topics: Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Agents; Cerebral Angiography; Cyanosis; Cyclooxygenase Inhibitors; Ductus Arteriosus; Ductus Arteriosus, Patent; Heart Defects, Congenital; Heart Failure; Hemodynamics; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Respiratory Distress Syndrome, Newborn; Vasodilator Agents | 2005 |
Novel therapeutic opportunities for Alzheimer's disease: focus on nonsteroidal anti-inflammatory drugs.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Animals; Animals, Genetically Modified; Anti-Inflammatory Agents, Non-Steroidal; Cell Culture Techniques; Cyclooxygenase Inhibitors; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Flurbiprofen; Humans; Ibuprofen; Indomethacin; Inflammation; Models, Biological; Models, Chemical; Models, Genetic; NF-kappa B; Peptides; Peroxisome Proliferator-Activated Receptors; PPAR gamma; Prostaglandin-Endoperoxide Synthases | 2005 |
Ibuprofen for the treatment of patent ductus arteriosus in preterm and/or low birth weight infants.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Enzyme Inhibitors; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Randomized Controlled Trials as Topic | 2005 |
[Non-steroid anti-inflammatory drugs in the treatment of Alzheimer's disease].
Topics: Aged; Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Indomethacin; Mice; Sulindac | 2005 |
Systematic review: intravenous Ibuprofen in preterm newborns.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Injections, Intravenous; Male; Randomized Controlled Trials as Topic | 2006 |
[Ibuprofen versus indomethacin in the preterm persistent patent ductus arteriosus therapy: review and meta-analysis].
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Echocardiography; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature | 2007 |
Ibuprofen for the treatment of patent ductus arteriosus in preterm and/or low birth weight infants.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Randomized Controlled Trials as Topic | 2008 |
Treatment of patent ductus arteriosus: indomethacin or ibuprofen?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Lysine | 2008 |
Ibuprofen lysine for the prevention and treatment of patent ductus arteriosus.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Female; Fetus; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Pregnancy; Randomized Controlled Trials as Topic; Regional Blood Flow | 2008 |
The diagnosis, management, and postnatal prevention of intraventricular hemorrhage in the preterm neonate.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Coagulants; Cyclooxygenase Inhibitors; Factor VIIa; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Phenobarbital | 2008 |
Therapeutic closure of the ductus arteriosus: benefits and limitations.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Evidence-Based Medicine; Gestational Age; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases | 2009 |
Nonsteroidal anti-inflammatory drugs (NSAIDs) in the newborn - which ones?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Hemorrhage; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Ketorolac | 2009 |
Treatment of persistent patent ductus arteriosus in preterm infants: time to accept the null hypothesis?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cardiac Surgical Procedures; Confidence Intervals; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Ligation; Respiratory Distress Syndrome, Newborn; Treatment Outcome | 2010 |
Ibuprofen for the treatment of patent ductus arteriosus in preterm and/or low birth weight infants.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Randomized Controlled Trials as Topic | 2010 |
Network meta-analysis of indomethacin versus ibuprofen versus placebo for PDA in preterm infants.
Topics: Cardiovascular Agents; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Randomized Controlled Trials as Topic; Treatment Outcome | 2011 |
Protective strategies to prevent patent ductus arteriosus.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Ligation; Time Factors | 2010 |
Patent ductus arteriosus in preterm infants.
Topics: Biomarkers; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Echocardiography; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Natriuretic Peptide, Brain | 2011 |
Patent ductus arteriosus: wait and see?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Patient Selection; Watchful Waiting | 2011 |
Should we definitively abandon prophylaxis for patent ductus arteriosus in preterm new-borns?
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Extremely Low Birth Weight; Infant, Newborn; Infant, Premature, Diseases; Intracranial Hemorrhages; Ligation | 2011 |
Evidence-based use of indomethacin and ibuprofen in the neonatal intensive care unit.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Evidence-Based Medicine; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Intensive Care Units, Neonatal | 2012 |
Oral ibuprofen versus intravenous ibuprofen or intravenous indomethacin for the treatment of patent ductus arteriosus in preterm infants: a systematic review and meta-analysis.
Topics: Administration, Oral; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infusions, Intravenous; Randomized Controlled Trials as Topic | 2012 |
Managing the patent ductus arteriosus in the premature neonate: a new look at what we thought we knew.
Topics: Acetaminophen; Biomarkers; Dose-Response Relationship, Drug; Ductus Arteriosus, Patent; Echocardiography; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Male; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Precision Medicine; Pregnancy; Time Factors | 2012 |
Non-steroidal anti-inflammatory drugs for the treatment of cancer cachexia: a systematic review.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cachexia; Celecoxib; Cyclooxygenase 2 Inhibitors; Humans; Ibuprofen; Indomethacin; Neoplasms; Pyrazoles; Quality of Life; Sulfonamides; Treatment Outcome | 2013 |
Clinical pharmacology of the loop diuretics furosemide and bumetanide in neonates and infants.
Topics: Acetazolamide; Bumetanide; Drug Therapy, Combination; Ductus Arteriosus, Patent; Extracorporeal Membrane Oxygenation; Furosemide; Humans; Hydrocephalus; Hypercalcemia; Ibuprofen; Indomethacin; Infant; Infant, Newborn; Infant, Premature; Sodium Potassium Chloride Symporter Inhibitors | 2012 |
[Hepatic encephalopathy].
Topics: Amino Acids, Branched-Chain; Ammonia; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Automobile Driving; Brain; Diet, Protein-Restricted; Disability Evaluation; Gastrointestinal Agents; Hepatic Encephalopathy; Humans; Ibuprofen; Indomethacin; Lactulose; Nerve Net; Neuroglia; Neurologic Examination; Neuronal Plasticity; Neuropsychological Tests; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Probiotics; Prognosis; Rifamycins; Rifaximin | 2012 |
Pharmacogenetics of nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Aspirin; Celecoxib; Cytochrome P-450 CYP2C9; Diclofenac; Humans; Ibuprofen; Indomethacin; Pharmacogenetics; Pyrazoles; Sulfonamides | 2012 |
[Progresses in treatment of patent ductus arteriosus in premature infants].
Topics: Ductus Arteriosus; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Ligation; Treatment Outcome | 2012 |
Ibuprofen for the treatment of patent ductus arteriosus in preterm and/or low birth weight infants.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Enterocolitis, Necrotizing; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Randomized Controlled Trials as Topic | 2013 |
Therapeutic manipulation of the ductus arteriosus: current options and future prospects.
Topics: Ductus Arteriosus, Patent; Female; Forecasting; Hemodynamics; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Male | 2014 |
Clinical pharmacology of ibuprofen and indomethacin in preterm infants with patent ductus arteriosus.
Topics: Cyclooxygenase Inhibitors; Dinoprostone; Drug Administration Schedule; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Male; Pregnancy; Treatment Outcome | 2014 |
Colchicine for pericarditis.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colchicine; Humans; Ibuprofen; Indomethacin; Pericarditis; Randomized Controlled Trials as Topic; Recurrence | 2014 |
Safety of therapeutics used in management of patent ductus arteriosus in preterm infants.
Topics: Acetaminophen; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant; Infant, Newborn; Infant, Premature; Pregnancy | 2015 |
Guidelines for feeding very low birth weight infants.
Topics: Breast Feeding; Canada; Enema; Enteral Nutrition; Fetal Blood; Food, Fortified; Gastroesophageal Reflux; Glycerol; Humans; Hypotension; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Meta-Analysis as Topic; Milk, Human; Nutrition Policy; Nutritional Status; Randomized Controlled Trials as Topic; Ventilation | 2015 |
Ibuprofen for the treatment of patent ductus arteriosus in preterm or low birth weight (or both) infants.
Topics: Administration, Oral; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Enterocolitis, Necrotizing; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Injections, Intravenous; Randomized Controlled Trials as Topic; Treatment Failure | 2015 |
Paracetamol (acetaminophen) for patent ductus arteriosus in preterm or low-birth-weight infants.
Topics: Acetaminophen; Administration, Oral; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Oxygen Inhalation Therapy; Randomized Controlled Trials as Topic | 2015 |
Nonaspirin Nonsteroidal Anti-Inflammatory Drugs and Risk of Hemorrhagic Stroke: A Systematic Review and Meta-Analysis of Observational Studies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cerebral Hemorrhage; Diclofenac; Humans; Ibuprofen; Incidence; Indomethacin; Lactones; Meloxicam; Naproxen; Observational Studies as Topic; Odds Ratio; Piroxicam; Proportional Hazards Models; Stroke; Sulfones; Thiazines; Thiazoles | 2016 |
Non-steroidal anti-inflammatory drugs for chronic low back pain.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Diclofenac; Disability Evaluation; Humans; Ibuprofen; Indomethacin; Low Back Pain; Pain Measurement; Piroxicam; Randomized Controlled Trials as Topic | 2016 |
Recent Advances in the Treatment of Preterm Newborn Infants with Patent Ductus Arteriosus.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Cardiac Catheterization; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Intensive Care Units, Neonatal; Ligation | 2016 |
Pharmacological Closure of Patent Ductus Arteriosus: Selecting the Agent and Route of Administration.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Decision Making; Drug Administration Routes; Ductus Arteriosus, Patent; Epoprostenol; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Premature; Renal Insufficiency | 2016 |
Principles of Clinical Management of Patent Ductus Arteriosus in Extremely Preterm Neonates.
Topics: Acetaminophen; Anterior Cerebral Artery; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Echocardiography, Doppler, Pulsed; Hemodynamics; Humans; Ibuprofen; Indomethacin; Infant, Extremely Premature; Infant, Low Birth Weight; Infant, Newborn; Infusions, Intravenous; Ligation; Practice Guidelines as Topic; Randomized Controlled Trials as Topic | 2016 |
Pharmacotherapy for Patent Ductus Arteriosus: Current Options and Outstanding Questions.
Topics: Acetaminophen; Cost-Benefit Analysis; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Extremely Premature; Infant, Newborn; Infant, Very Low Birth Weight; Infusions, Intravenous; Practice Guidelines as Topic; Randomized Controlled Trials as Topic | 2016 |
Surgical Intervention in Preterm Neonates with Patent Ductus Arteriosus.
Topics: Bronchopulmonary Dysplasia; Combined Modality Therapy; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Enterocolitis, Necrotizing; Humans; Ibuprofen; Indomethacin; Infant, Extremely Premature; Infant, Newborn; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Ligation; Postoperative Complications; Practice Guidelines as Topic; Respiratory Distress Syndrome, Newborn | 2016 |
Patent Ductus Arteriosus and Short- and Long-Term Respiratory Outcomes.
Topics: Bronchopulmonary Dysplasia; Ductus Arteriosus, Patent; Hemodynamics; Humans; Ibuprofen; Indomethacin; Infant, Extremely Premature; Infant, Newborn; Lung; Randomized Controlled Trials as Topic | 2016 |
Patent Ductus Arteriosus in the Preterm Infant: Diagnostic and Treatment Options.
Topics: Biomarkers; Cardiac Catheterization; Conservative Treatment; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Echocardiography; Enterocolitis, Necrotizing; Fluid Therapy; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Natriuretic Peptide, Brain; Peptide Fragments; Renal Insufficiency; Septal Occluder Device | 2017 |
The use of non-steroidal anti-inflammatory drugs for patent ductus arteriosus closure in preterm infants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Treatment Outcome | 2017 |
Prediction of Therapeutic Response to Cyclooxygenase Inhibitors in Preterm Infants with Patent Ductus Arteriosus.
Topics: Biomarkers, Pharmacological; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Echocardiography; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature | 2018 |
Genetics of the patent ductus arteriosus (PDA) and pharmacogenetics of PDA treatment.
Topics: Acetaminophen; Animals; Disease Models, Animal; Ductus Arteriosus, Patent; Genetic Predisposition to Disease; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Pharmacogenetics | 2018 |
Prophylactic and early targeted treatment of patent ductus arteriosus.
Topics: Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature | 2018 |
Association of Placebo, Indomethacin, Ibuprofen, and Acetaminophen With Closure of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Infants: A Systematic Review and Meta-analysis.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Bayes Theorem; Cerebral Hemorrhage; Ductus Arteriosus, Patent; Enterocolitis, Necrotizing; Hemodynamics; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Randomized Controlled Trials as Topic; Risk Factors | 2018 |
Paracetamol (acetaminophen) for patent ductus arteriosus in preterm or low birth weight infants.
Topics: Acetaminophen; Administration, Oral; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Injections, Intravenous; Oxygen Inhalation Therapy; Randomized Controlled Trials as Topic; Treatment Outcome | 2018 |
Novel drug targets for ductus arteriosus manipulation: Looking beyond prostaglandins.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; KATP Channels; Models, Animal; Proof of Concept Study; Vascular Patency | 2018 |
Pre-symptomatic targeted treatment of patent ductus arteriosus in preterm newborns: A systematic review and meta-analysis.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Echocardiography; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Randomized Controlled Trials as Topic | 2019 |
Pharmacotherapy for patent ductus arteriosus closure.
Topics: Acetaminophen; Administration, Oral; Antipyretics; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infusions, Intravenous; Treatment Outcome | 2019 |
An Overview of Systematic Reviews of Randomized-Controlled Trials for Preventing Necrotizing Enterocolitis in Preterm Infants.
Topics: Administration, Oral; Adrenal Cortex Hormones; Ductus Arteriosus, Patent; Enterocolitis, Necrotizing; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Meta-Analysis as Topic; Pregnancy; Premature Birth; Probiotics; Randomized Controlled Trials as Topic; Systematic Reviews as Topic | 2020 |
To Feed or Not to Feed: A Critical Overview of Enteral Feeding Management and Gastrointestinal Complications in Preterm Neonates with a Patent Ductus Arteriosus.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Enteral Nutrition; Gastrointestinal Diseases; Hemodynamics; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; PubMed; Splanchnic Circulation | 2019 |
Paracetamol (acetaminophen) for patent ductus arteriosus in preterm or low birth weight infants.
Topics: Acetaminophen; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Odds Ratio; Randomized Controlled Trials as Topic | 2020 |
Ibuprofen for the prevention of patent ductus arteriosus in preterm and/or low birth weight infants.
Topics: Cerebral Hemorrhage; Cyclooxygenase Inhibitors; Drug-Related Side Effects and Adverse Reactions; Ductus Arteriosus, Patent; Enterocolitis, Necrotizing; Enzyme Inhibitors; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Randomized Controlled Trials as Topic | 2020 |
Early treatment versus expectant management of hemodynamically significant patent ductus arteriosus for preterm infants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cause of Death; Cerebral Intraventricular Hemorrhage; Chronic Disease; Ductus Arteriosus, Patent; Enterocolitis, Necrotizing; Hemodynamics; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Ligation; Lung Diseases; Pneumothorax; Randomized Controlled Trials as Topic; Time Factors; Time-to-Treatment; Watchful Waiting | 2020 |
Early closure mechanisms of the ductus arteriosus in immature infants.
Topics: Ductus Arteriosus; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant; Infant, Newborn; Infant, Premature | 2021 |
Acetaminophen Therapy for Persistent Patent Ductus Arteriosus.
Topics: Acetaminophen; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Extremely Premature; Infant, Newborn | 2021 |
Comparative safety and efficacy of paracetamol versus non-steroidal anti-inflammatory agents in neonates with patent ductus arteriosus: A systematic review and meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Randomized Controlled Trials as Topic | 2022 |
Efficacy and Costs of Three Pharmacotherapies for Patent Ductus Arteriosus Closure in Premature Infants.
Topics: Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight | 2022 |
Dual Therapy vs. Monotherapy for the Patent Ductus Arteriosus: A Systematic Review.
Topics: Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature | 2022 |
Efficacy and safety of high versus standard dose ibuprofen for patent ductus arteriosus treatment in preterm infants: A systematic review and meta-analysis.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature | 2022 |
Dual medication therapy (acetaminophen and ibuprofen) for the management of patent ductus arteriosus in preterm infants: a systematic review and meta-analysis.
Topics: Acetaminophen; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature | 2022 |
A Network Meta-Analysis of Intravenous Versus Oral Acetaminophen for Patent Ductus Arteriosus.
Topics: Acetaminophen; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Network Meta-Analysis; Randomized Controlled Trials as Topic | 2023 |
Paracetamol (acetaminophen) for patent ductus arteriosus in preterm or low birth weight infants.
Topics: Acetaminophen; Drug Therapy, Combination; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Randomized Controlled Trials as Topic | 2022 |
Association of patent ductus arteriosus with fetal factors and endotypes of prematurity.
Topics: Ductus Arteriosus, Patent; Female; Fetal Growth Retardation; Humans; Ibuprofen; Indomethacin; Infant; Infant, Extremely Premature; Infant, Newborn; Premature Birth | 2023 |
Combination pharmacotherapy for patent ductus arteriosus: Rationale and evidence.
Topics: Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature | 2023 |
Interventions for patent ductus arteriosus (PDA) in preterm infants: an overview of Cochrane Systematic Reviews.
Topics: Acetaminophen; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Prostaglandin Antagonists; Systematic Reviews as Topic | 2023 |
Acetaminophen for the patent ductus arteriosus: has safety been adequately demonstrated?
Topics: Acetaminophen; Cytochrome P-450 CYP2E1; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Extremely Premature; Infant, Low Birth Weight; Infant, Newborn | 2023 |
Expectant management of patent ductus arteriosus for preterm infants: A meta-analysis of randomized controlled trials.
Topics: Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Randomized Controlled Trials as Topic; Watchful Waiting | 2023 |
87 trial(s) available for ibuprofen and indomethacin
| Article | Year |
|---|---|
Evaluation of analgesic action and efficacy of antirheumatic drugs. Study of 10 drugs in 684 patients with rheumatoid arthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Flurbiprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Mefenamic Acid; Pain; Phenylacetates; Placebos; Prednisone; Salicylates | 1976 |
Prostaglandin-synthesis inhibitors in prophylaxis of food intolerance.
Topics: Acute Disease; Adult; Animals; Aspirin; Bivalvia; Chickens; Clinical Trials as Topic; Dairy Products; Eggs; Female; Food Hypersensitivity; Gastrointestinal Diseases; Humans; Ibuprofen; Indomethacin; Male; Meat; Middle Aged; Prostaglandins E; Prostaglandins F; Swine; Zea mays | 1978 |
Prostaglandin synthetase inhibitors and dysmenorrhea. A survey and personal clinical experience.
Topics: Adolescent; Adult; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Evaluation; Dysmenorrhea; Female; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Naproxen; ortho-Aminobenzoates; Placebos; Prostaglandin Antagonists | 1979 |
A long-term double-blind clinical trial of ibuprofen and indomethacin in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Double-Blind Method; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Time Factors | 1975 |
Asthma improved by nonsteroidal anti-inflammatory drugs.
Topics: Airway Resistance; Anti-Inflammatory Agents; Aspirin; Asthma; Clinical Trials as Topic; Female; Forced Expiratory Volume; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Middle Aged; Phenylbutazone; Placebos; Respiratory Function Tests; Sodium Salicylate; Spirometry; Tartrazine | 1978 |
Hypersensitivity to five non-steroidal anti-inflammatory agents: ibuprofen, fenoprofen, indomethacin, naproxen and tolmetin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Drug Hypersensitivity; Fenoprofen; Humans; Ibuprofen; Indomethacin; Iodides; Naproxen; Tolmetin | 1978 |
A comparative study on ibuprofen (Brufen) and indomethacin in non-articular rheumatism.
Topics: Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Indomethacin; Male; Rheumatic Diseases | 1978 |
A comparative study of indomethacin and ibuprofen.
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged | 1979 |
Tolfenamic acid in the treatment of rheumatoid arthritis.
Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Drug Evaluation; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; ortho-Aminobenzoates; Phenylbutazone; Prednisone; Time Factors | 1979 |
A crossover clinical trial of piroxicam, indomethacin and ibuprofen in rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Tolerance; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Pyridines; Thiazines | 1979 |
Analysis of the Brazilian literature on diclofenac sodium (Voltarol).
Topics: Arthritis, Rheumatoid; Brazil; Clinical Trials as Topic; Diclofenac; Drug Tolerance; Female; Humans; Ibuprofen; Indomethacin; Male; Osteoarthritis; Time Factors | 1979 |
The effects of ibuprofen, indomethacin, aspirin, naproxen, and placebo on the gastric mucosa of normal volunteers: a gastroscopic and photographic study.
Topics: Adult; Aspirin; Gastric Mucosa; Gastroscopy; Humans; Ibuprofen; Indomethacin; Middle Aged; Naproxen; Placebos | 1979 |
Renal prostaglandins and sodium balance in normal man.
Topics: Adult; Diet, Sodium-Restricted; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Prostaglandins E; Sodium; Water-Electrolyte Balance | 1979 |
[Treatment of arthrosis deformans with indomethacin and ibuprofen; a comparative study].
Topics: Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Phenylpropionates | 1975 |
Sulindac in osteoarthrosis of the hip.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Osteoarthritis | 1976 |
Ketoprofen - clinical efficacy.
Topics: Acetaminophen; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Aspirin; Benzophenones; Clinical Trials as Topic; Gout; Humans; Ibuprofen; Indomethacin; Ketoprofen; Phenylbutazone; Placebos; Sciatica; Spondylitis, Ankylosing | 1976 |
A six-month double-blind trial of ibuprofen and indomethacin in osteoarthritis.
Topics: Adult; Central Nervous System; Clinical Trials as Topic; Digestive System; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Osteoarthritis; Pain; Physical Exertion; Propionates | 1975 |
Synergistic effects of oral nonsteroidal drugs and topical corticosteroids in the therapy of sunburn in humans.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents; Betamethasone; Biopsy; Blood Flow Velocity; Drug Synergism; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Ibuprofen; Indomethacin; Lasers; Male; Middle Aged; Random Allocation; Skin; Sunburn | 1992 |
Interaction between digoxin and indomethacin or ibuprofen.
Topics: Aged; Aged, 80 and over; Digoxin; Drug Interactions; Female; Fluorescence Polarization Immunoassay; Humans; Ibuprofen; Indomethacin; Male; Middle Aged | 1991 |
The effects of ibuprofen and indomethacin on renal function in the presence and absence of frusemide in healthy volunteers on a restricted sodium diet.
Topics: Adult; Blood Pressure; Diet, Sodium-Restricted; Furosemide; Glomerular Filtration Rate; Humans; Ibuprofen; Indomethacin; Inulin; Kidney; Kidney Function Tests; Male; Natriuresis; p-Aminohippuric Acid; Potassium; Renal Circulation; Renin; Sodium | 1990 |
The effective treatment of postpericardiotomy syndrome after cardiac operations. A randomized placebo-controlled trial.
Topics: Cardiac Surgical Procedures; Double-Blind Method; Female; Heart Diseases; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Placebos; Postpericardiotomy Syndrome; Randomized Controlled Trials as Topic | 1990 |
Prevention of non-steroidal anti-inflammatory agents induced acute gastric mucosal lesions by carbonic anhydrase inhibitors. An endoscopic study.
Topics: Acetazolamide; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Mucosa; Gastroscopy; Humans; Ibuprofen; Indomethacin; Male; Phenylbutazone; Random Allocation; Stomach Ulcer | 1989 |
A comparison of the effects of ibuprofen and indomethacin upon renal haemodynamics and electrolyte excretion in the presence and absence of frusemide.
Topics: Adult; Creatinine; Electrolytes; Furosemide; Humans; Ibuprofen; Indomethacin; Male; p-Aminohippuric Acid; Potassium; Renal Circulation; Renin; Time Factors | 1989 |
An endoscopic comparison of the effects of etodolac, indomethacin, ibuprofen, naproxen, and placebo on the gastrointestinal mucosa.
Topics: Acetates; Adolescent; Adult; Endoscopy; Etodolac; Gastric Mucosa; Humans; Ibuprofen; Indomethacin; Intestinal Mucosa; Middle Aged; Naproxen; Placebos | 1987 |
Treatment of nephrogenic diabetes insipidus with prostaglandin synthesis inhibitors.
Topics: Adolescent; Blood Urea Nitrogen; Child; Chlorothiazide; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Diabetes Insipidus; Diuresis; Drug Therapy, Combination; Humans; Ibuprofen; Indomethacin; Kidney Concentrating Ability; Male; Natriuresis; Osmolar Concentration; Urine | 1986 |
Four popular anti-inflammatories. Which?
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Drug Evaluation; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Piroxicam; Random Allocation | 1988 |
International experience with diclofenac in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Humans; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone | 1986 |
International experiences with diclofenac in osteoarthritis.
Topics: Aspirin; Clinical Trials as Topic; Diclofenac; Diflunisal; Double-Blind Method; Gastrointestinal Diseases; Humans; Ibuprofen; Indomethacin; Naproxen; Osteoarthritis; Random Allocation; Sulindac | 1986 |
Proquazone: a treatment for lymphocytic infiltration of the skin. Comparative study with 2 other nonsteroid anti-inflammatory drugs.
Topics: Adult; Aged; Clinical Trials as Topic; Erythema; Female; Humans; Ibuprofen; Indomethacin; Lymphocytes; Male; Middle Aged; Quinazolines | 1987 |
Prostaglandins and nicotinate-provoked increase in cutaneous blood flow.
Topics: Administration, Oral; Administration, Topical; Adult; Aspirin; Double-Blind Method; Doxepin; Drug Interactions; Erythema; Female; Humans; Ibuprofen; Indomethacin; Male; Nicotinic Acids; Prostaglandins; Random Allocation; Skin; Structure-Activity Relationship; Vasodilation | 1985 |
Clinical use of tolmetin sodium in patients with ankylosing spondylitis: a review.
Topics: Clinical Trials as Topic; Double-Blind Method; Humans; Ibuprofen; Indomethacin; Pyrroles; Spondylitis, Ankylosing; Tolmetin | 1983 |
A multi-centre study of tiaprofenic acid ('Surgam') and five comparative drugs in rheumatoid arthritis and osteoarthritis in general practice.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Osteoarthritis; Patient Compliance; Propionates; Sex Factors; Thiazines | 1983 |
Comparative efficacy of ibuprofen, indomethacin, and placebo in the treatment of primary dysmenorrhea.
Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea; Female; Humans; Ibuprofen; Indomethacin; Random Allocation; Time Factors | 1983 |
Review of ibuprofen for osteoarthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Meclofenamic Acid; Naproxen; Osteoarthritis; Phenylbutazone; Sulindac; Tolmetin | 1984 |
Update on ibuprofen for rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Clinical Trials as Topic; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Piroxicam; Sulindac; Thiazines; Tolmetin | 1984 |
Effect of different prostaglandin synthesis inhibitors on post-occlusive blood flow in human forearm.
Topics: Adolescent; Adult; Aspirin; Cyclooxygenase Inhibitors; Diclofenac; Female; Forearm; Humans; Hyperemia; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Piroxicam; Regional Blood Flow; Thiazines | 1983 |
Prostaglandin synthetase inhibitors in the treatment of primary dysmenorrhea. Outcome trials reviewed.
Topics: Clinical Trials as Topic; Cyclooxygenase Inhibitors; Dysmenorrhea; Female; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Naproxen | 1984 |
[Comparative clinical study of the efficacy of and tolerance for lysine para-isobutylphenyl propionate in parallel with indomethacin and pyrasanone].
Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Drug Tolerance; Female; Humans; Ibuprofen; Indomethacin; Lysine; Male; Middle Aged; Phenylbutazone; Rheumatic Diseases; Time Factors | 1980 |
Endoscopic studies of gastric and duodenal injury after the use of ibuprofen, aspirin, and other nonsteroidal anti-inflammatory agents.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Aspirin; Buffers; Duodenum; Endoscopy; Female; Gastric Mucosa; Humans; Ibuprofen; Indomethacin; Intestinal Mucosa; Male; Middle Aged; Naproxen; Time Factors; Tolmetin | 1984 |
Comparison of the analgesic effect of ten nonsteroidal anti-inflammatory drugs.
Topics: Adult; Aged; Analgesics; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Carbazoles; Diclofenac; Female; Humans; Ibuprofen; Indomethacin; Ketoprofen; Male; Middle Aged; Naproxen; ortho-Aminobenzoates; Quinazolines | 1984 |
[A clinical study on the effect of K-708 (acemetacin)--a double blind comparative study with ibuprofen in upper respiratory tract inflammation with fever (author's transl)].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Double-Blind Method; Female; Fever; Humans; Ibuprofen; Indoleacetic Acids; Indomethacin; Male; Middle Aged; Respiratory Tract Infections | 1981 |
A comparative endoscopic evaluation of the damaging effects of nonsteroidal anti-inflammatory agents on the gastric and duodenal mucosa.
Topics: Adult; Anti-Inflammatory Agents; Duodenum; Endoscopy; Gastric Mucosa; Humans; Ibuprofen; Indomethacin; Intestinal Mucosa; Middle Aged; Naproxen; Tolmetin | 1981 |
Naproxen suppositories in combination with oral naproxen, indomethacin and ibuprofen in the treatment of rheumatoid arthritis.
Topics: Administration, Oral; Adult; Aged; Arthritis, Rheumatoid; Drug Therapy, Combination; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Suppositories | 1980 |
Nonsteroidal anti-inflammatory drug use in relation to major upper gastrointestinal bleeding.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Control Studies; Diclofenac; Female; Gastrointestinal Hemorrhage; Humans; Hungary; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Piroxicam; Risk Factors; Sweden; United States | 1993 |
Treatment of patent ductus arteriosus with ibuprofen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Administration Schedule; Ductus Arteriosus, Patent; Echocardiography, Doppler; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Injections, Intravenous; Prospective Studies; Respiratory Distress Syndrome, Newborn; Urination | 1997 |
Comparative evaluation of the effects of indomethacin and ibuprofen on cerebral perfusion and oxygenation in preterm infants with patent ductus arteriosus.
Topics: Blood Flow Velocity; Brain; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ductus Arteriosus, Patent; Echoencephalography; Electron Transport Complex IV; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Male; Oximetry; Oxygen Inhalation Therapy; Regional Blood Flow; Ultrasonography, Doppler | 1997 |
Ibuprofen vs indomethacin for treatment of PDA in preterm infants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Drug Administration Schedule; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; India; Indomethacin; Infant, Newborn; Infant, Premature; Injections, Intravenous; Male; Treatment Outcome | 1998 |
Contrasting actions of pressor agents in severe autonomic failure.
Topics: Aged; Autonomic Agents; Blood Pressure; Caffeine; Catecholamines; Female; Heart Rate; Humans; Hypotension, Orthostatic; Ibuprofen; Indomethacin; Male; Methylphenidate; Phenylpropanolamine; Regression Analysis; Single-Blind Method; Yohimbine | 1998 |
Characterization of rofecoxib as a cyclooxygenase-2 isoform inhibitor and demonstration of analgesia in the dental pain model.
Topics: Adult; Analgesics, Non-Narcotic; Animals; CHO Cells; Cricetinae; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Female; Humans; Ibuprofen; Indomethacin; Isoenzymes; Lactones; Male; Models, Biological; Pain; Prostaglandin-Endoperoxide Synthases; Sulfones; Tooth | 1999 |
Prostaglandin inhibition causes an increase in reactive hyperaemia after ischaemic exercise in human forearm.
Topics: Adult; Cyclooxygenase Inhibitors; Forearm; Humans; Hyperemia; Ibuprofen; Indomethacin; Ischemia; Male; Muscle, Skeletal; Physical Exertion; Platelet Aggregation; Prostaglandin Antagonists; Prostaglandins; Regional Blood Flow; Stress, Mechanical; Vasodilation | 1999 |
No effective prophylaxis of heterotopic ossification with short-term ibuprofen.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Ossification, Heterotopic; Osteoarthritis, Hip; Postoperative Complications; Prospective Studies; Treatment Failure | 1999 |
Randomized double-blind controlled trial comparing the effects of ibuprofen with indomethacin on cerebral hemodynamics in preterm infants with patent ductus arteriosus.
Topics: Brain; Double-Blind Method; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Regional Blood Flow | 2000 |
Prophylactic ibuprofen therapy of patent ductus arteriosus in preterm infants.
Topics: Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infusions, Intravenous; Male | 2000 |
A comparison of ibuprofen and indomethacin for closure of patent ductus arteriosus.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Oliguria; Prospective Studies; Respiratory Distress Syndrome, Newborn; Survival Rate; Treatment Outcome | 2000 |
[Antihypertensive effect of enalapril and lisinopril administered in combination with nonsteroid anti-inflammatory agents].
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Drug Antagonism; Enalapril; Female; Humans; Hypertension; Ibuprofen; Indomethacin; Lisinopril; Male; Middle Aged; Osteochondritis | 2001 |
Safety and efficacy of ibuprofen versus indomethacin in preterm infants treated for patent ductus arteriosus: a randomised controlled trial.
Topics: Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Male; Treatment Outcome | 2002 |
Ibuprofen prophylaxis in preterm neonates.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Hypertension, Pulmonary; Hypoxia; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature, Diseases | 2002 |
Oral ibuprofen and indomethacin for treatment of patent ductus arteriosus in premature infants: a randomized trial at Ramathibodi Hospital.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Prospective Studies | 2002 |
Comparison of ibuprofen and indomethacin therapy for patent ductus arteriosus in preterm infants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Infusions, Intravenous; Male; Respiratory Distress Syndrome, Newborn | 2003 |
A comparison of oral ibuprofen and intravenous indomethacin for closure of patent ductus arteriosus in preterm infants.
Topics: Administration, Oral; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Injections, Intravenous; Male; Statistics, Nonparametric; Treatment Outcome | 2003 |
Relationships between the concentrations of prostaglandins and the nonsteroidal antiinflammatory drugs indomethacin, diclofenac, and ibuprofen.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Capsules; Cross-Over Studies; Diclofenac; Dinoprostone; Dose-Response Relationship, Drug; Female; Humans; Ibuprofen; Indomethacin; Male; Tablets; Time Factors | 2005 |
[Ibuprofen versus indomethacin in the treatment of patent ductus arteriosus in preterm infants].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male | 2005 |
Impact of ibuprofen administration on renal drug clearance in the first weeks of life.
Topics: Age Factors; Amikacin; Anti-Bacterial Agents; Aspirin; Betamethasone; Birth Weight; Cyclooxygenase Inhibitors; Double-Blind Method; Ductus Arteriosus, Patent; Female; Glomerular Filtration Rate; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infusions, Intravenous; Kidney; Metabolic Clearance Rate; Postmenopause; Pregnancy; Time Factors; Vancomycin | 2006 |
Oral Ibuprofen and ductus arteriosus in premature infants: a randomized pilot study.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Echocardiography, Doppler; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infusions, Intravenous; Male; Pilot Projects; Severity of Illness Index; Single-Blind Method; Suspensions; Treatment Outcome | 2007 |
Comparison of ibuprofen and indometacin for early-targeted treatment of patent ductus arteriosus in extremely premature infants: a randomised controlled trial.
Topics: Analysis of Variance; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Prospective Studies; Treatment Outcome; Ultrasonography | 2008 |
Comparison of oral ibuprofen and indomethacin therapy for patent ductus arteriosus in preterm infants.
Topics: Administration, Oral; Ductus Arteriosus, Patent; Enterocolitis, Necrotizing; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature | 2007 |
Ibuprofen versus continuous indomethacin in premature neonates with patent ductus arteriosus: is the difference in the mode of administration?
Topics: Blood Flow Velocity; Cerebral Arteries; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Glomerular Filtration Rate; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infusions, Intravenous; Kidney; Mesenteric Artery, Superior; Treatment Outcome | 2008 |
Pharmacological closure of patent ductus arteriosus: effects on pulse pressure and on endothelin-1 and vasopressin excretion.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arginine Vasopressin; Blood Pressure; Ductus Arteriosus, Patent; Endothelin-1; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Treatment Failure | 2008 |
The effect of premedication with ibuprofen and indomethacin on the success of inferior alveolar nerve block for teeth with irreversible pulpitis.
Topics: Adult; Analysis of Variance; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Indomethacin; Lidocaine; Male; Mandible; Mandibular Nerve; Molar; Nerve Block; Pain; Pain Measurement; Preanesthetic Medication; Premedication; Prospective Studies; Pulpitis; Root Canal Therapy; Treatment Outcome; Young Adult | 2010 |
Enteral feeding during indomethacin and ibuprofen treatment of a patent ductus arteriosus.
Topics: Combined Modality Therapy; Ductus Arteriosus, Patent; Enteral Nutrition; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Male; Prospective Studies; Time Factors | 2013 |
Superior mesenteric artery blood flow velocities following medical treatment of a patent ductus arteriosus.
Topics: Blood Flow Velocity; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Enteral Nutrition; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Male; Mesenteric Artery, Superior; Ultrasonography, Doppler | 2014 |
Comparison of oral ibuprofen with oral indomethacin for PDA closure in Indian preterm neonates: a randomized controlled trial.
Topics: Administration, Oral; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; India; Indomethacin; Infant, Newborn; Infant, Premature; Male; Treatment Outcome | 2014 |
Randomized Trial to Compare Renal Function and Ductal Response between Indomethacin and Ibuprofen Treatment in Extremely Low Birth Weight Infants.
Topics: Creatinine; Cyclooxygenase Inhibitors; Double-Blind Method; Ductus Arteriosus; Ductus Arteriosus, Patent; Echocardiography; Female; Glomerular Filtration Rate; Humans; Ibuprofen; Indomethacin; Infant, Extremely Low Birth Weight; Infant, Newborn; Kidney; Male; Taiwan; Time Factors; Treatment Outcome; United States | 2017 |
Comparative study of the efficacy and safety of paracetamol, ibuprofen, and indomethacin in closure of patent ductus arteriosus in preterm neonates.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analysis of Variance; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Gestational Age; Humans; Ibuprofen; Indomethacin; Infant, Extremely Premature; Infant, Newborn; Infant, Very Low Birth Weight; Infusions, Intravenous; Intensive Care Units, Neonatal; Male; Prospective Studies | 2017 |
A Comparison of Early Ibuprofen and Indomethacin Administration to Prevent Intraventricular Hemorrhage Among Preterm Infants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cerebral Hemorrhage; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Incidence; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Iran; Male; Prevalence; Prospective Studies; Treatment Outcome | 2016 |
Efficacy of pharmacologic closure of patent ductus arteriosus in small-for-gestational-age extremely preterm infants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Extremely Premature; Infant, Newborn; Infant, Small for Gestational Age; Male | 2017 |
Oral indomethacin versus oral ibuprofen for treatment of patent ductus arteriosus: a randomised controlled study in very low-birthweight infants.
Topics: Administration, Oral; Cardiovascular Agents; Ductus Arteriosus, Patent; Echocardiography; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Very Low Birth Weight; Male; Treatment Outcome | 2018 |
PDA-TOLERATE Trial: An Exploratory Randomized Controlled Trial of Treatment of Moderate-to-Large Patent Ductus Arteriosus at 1 Week of Age.
Topics: Acetaminophen; Conservative Treatment; Continuous Positive Airway Pressure; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Gestational Age; Humans; Ibuprofen; Indomethacin; Infant, Extremely Premature; Infant, Newborn; Male; Prospective Studies; Single-Blind Method; Treatment Outcome | 2019 |
Comparative effectiveness of drugs used to constrict the patent ductus arteriosus: a secondary analysis of the PDA-TOLERATE trial (NCT01958320).
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Conservative Treatment; Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Extremely Premature; Infant, Newborn; Male; San Francisco; Treatment Outcome; Vasoconstriction | 2019 |
A randomized trial of intravenous acetaminophen versus indomethacin for treatment of hemodynamically significant PDAs in VLBW infants.
Topics: Acetaminophen; Administration, Oral; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant | 2021 |
Patent ductus arteriosus shunt elimination results in a reduction in adverse outcomes: a post hoc analysis of the PDA RCT cohort.
Topics: Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature | 2021 |
Relative effectiveness and safety of pharmacotherapeutic agents for patent ductus arteriosus (PDA) in preterm infants: a protocol for a multicentre comparative effectiveness study (CANRxPDA).
Topics: Canada; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant; Infant, Low Birth Weight; Infant, Newborn; Multicenter Studies as Topic; Observational Studies as Topic | 2021 |
Indomethacin has no effect on trigeminally provoked parasympathetic output.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Headache; Humans; Ibuprofen; Indomethacin; Paroxysmal Hemicrania; Trigeminal Autonomic Cephalalgias | 2022 |
Expectant Management or Early Ibuprofen for Patent Ductus Arteriosus.
Topics: Bronchopulmonary Dysplasia; Ductus Arteriosus, Patent; Echocardiography; Enterocolitis, Necrotizing; Humans; Ibuprofen; Indomethacin; Infant; Infant, Extremely Premature; Infant, Low Birth Weight; Infant, Newborn; Infant, Newborn, Diseases; Watchful Waiting | 2023 |
Platelets and ductus arteriosus closure in neonates.
Topics: Animals; Cyclooxygenase Inhibitors; Ductus Arteriosus; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant; Infant, Extremely Premature; Infant, Newborn; Mice | 2023 |
Cardiopulmonary Ultrasound-Guided Treatment of Premature Infants with Respiratory Failure and Patent Ductus Arteriosus: A Randomized, Controlled Trial.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Prospective Studies; Respiratory Insufficiency; Ultrasonography; Ultrasonography, Interventional | 2023 |
iPAPP: study protocol for a multicentre randomised controlled trial comparing safety and efficacy of intravenous paracetamol and indomethacin for the treatment of patent ductus arteriosus in preterm infants.
Topics: Acetaminophen; Administration, Intravenous; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Multicenter Studies as Topic; Randomized Controlled Trials as Topic | 2023 |
697 other study(ies) available for ibuprofen and indomethacin
| Article | Year |
|---|---|
2-(Substituted phenyl)oxazolo[4,5-b]pyridines and 2-(substituted phenyl)oxazolo[5,4-b]pyridines as nonacidic antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cyclooxygenase Inhibitors; Edema; Gastric Mucosa; Lethal Dose 50; Mice; Pyridines; Rats; Structure-Activity Relationship | 1978 |
Synthesis and antiinflammatory activity of cis-4,5,6,7,8,8a,9-hexahydro-alpha-methyl-5H-fluorene-2-acetic acid.
Topics: Animals; Anti-Inflammatory Agents; Arthus Reaction; Edema; Fluorenes; Magnetic Resonance Spectroscopy; Molecular Conformation; Rabbits; Rats; Stereoisomerism | 1977 |
Novel analgesic-antiinflammatory salicylates.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry; Dogs; Rats; Salicylates; Structure-Activity Relationship | 1978 |
Antinociceptive (aminoalkyl)indoles.
Topics: Analgesia; Analgesics; Animals; Chemical Phenomena; Chemistry; Cyclooxygenase Inhibitors; Indoles; Magnetic Resonance Spectroscopy; Male; Methylation; Mice; Molecular Conformation; Molecular Structure; Muscle Contraction; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Vas Deferens | 1991 |
1,2-Dihydro-1-oxopyrrolo[3,2,1-kl]phenothiazine-2-carboxamides and congeners, dual cyclooxygenase/5-lipoxygenase inhibitors with antiinflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cell Line; Cyclooxygenase Inhibitors; Edema; Indicators and Reagents; Lipoxygenase Inhibitors; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Models, Molecular; Molecular Structure; Prostaglandin Antagonists; Pyrroles; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Thiazines | 1990 |
Nonsteroidal antiinflammatory drug hydroxamic acids. Dual inhibitors of both cyclooxygenase and 5-lipoxygenase.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonate Lipoxygenases; Cyclooxygenase Inhibitors; Hydroxamic Acids; Ibuprofen; Indomethacin; Lipoxygenase Inhibitors; Meclofenamic Acid | 1990 |
Benzimidazole derivatives with atypical antiinflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experimental; Benzimidazoles; Carrageenan; Cyclooxygenase Inhibitors; Edema; Exocytosis; Humans; Lysosomes; Male; Neutrophils; Rats; Rats, Inbred Lew; Structure-Activity Relationship | 1987 |
Synthesis and antiinflammatory activity of hexahydrothiopyrano[4,3-c]pyrazoles and related analogues.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthus Reaction; Chemical Phenomena; Chemistry; Edema; Guinea Pigs; Hypersensitivity, Delayed; Male; Mice; Pyrazoles; Rats; Rats, Inbred Lew; Rats, Inbred Strains | 1982 |
Bulky amine analogues of ketoprofen: potent antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Edema; Indicators and Reagents; Ketoprofen; Magnetic Resonance Spectroscopy; Male; Phenylpropionates; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1984 |
Synthesis and antiinflammatory activity of [(cycloalkylmethyl)phenyl]acetic acids and related compounds.
Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Female; Fever; Ibuprofen; Indomethacin; Inflammation; Male; Phenylacetates; Phenylpropionates; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Structure-Activity Relationship | 1984 |
Nonsteroidal antiinflammatory agents. 14. Synthesis and pharmacological profile of 6-chloro-5-(cyclopentylmethyl)indan-1-carboxylic acid.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Edema; Indans; Indenes; Male; Rats; Rats, Inbred Strains | 1984 |
Effect of structural change on acute toxicity and antiinflammatory activity in a series of imidazothiazoles and thiazolobenzimidazoles.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Chemical Phenomena; Chemistry; Imidazoles; Lethal Dose 50; Locomotion; Male; Mice; Muscle Tonus; Nervous System; Orientation; Rats; Structure-Activity Relationship; Thiazoles | 1981 |
Antiinflammatory 4,5-diarylpyrroles. 2. Activity as a function of cyclooxygenase-2 inhibition.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Pyrroles; Rats; Structure-Activity Relationship | 1995 |
Antiinflammatory 4,5-diarylpyrroles: synthesis and QSAR.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Disease Models, Animal; Drug Tolerance; Male; Pyrroles; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 1994 |
Dibenzoxepinone hydroxylamines and hydroxamic acids: dual inhibitors of cyclooxygenase and 5-lipoxygenase with potent topical antiinflammatory activity.
Topics: 3T3 Cells; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Cyclooxygenase Inhibitors; Dibenzoxepins; Dinoprostone; Hydroxamic Acids; Hydroxyeicosatetraenoic Acids; Hydroxylamines; Lipoxygenase Inhibitors; Mice; Molecular Structure; Structure-Activity Relationship | 1996 |
Nonsteroidal anti-inflammatory drugs as scaffolds for the design of 5-lipoxygenase inhibitors.
Topics: Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Drug Design; Humans; Hydroxyurea; Ibuprofen; Indomethacin; Leukocytes; Leukotriene E4; Lipoxygenase Inhibitors; Magnetic Resonance Spectroscopy; Male; Naproxen; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Tumor Cells, Cultured | 1997 |
Interactions of nonsteroidal anti-inflammatory drugs with rat renal organic anion transporter, OAT-K1.
Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Carrier Proteins; Drug Interactions; Indomethacin; Ketoprofen; Kidney; Male; Methotrexate; Rats; Rats, Wistar; Tetraethylammonium Compounds | 1997 |
Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis.
Topics: Animals; Biological Assay; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Kinetics; Placenta; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sheep | 1998 |
Ursolic acid from Plantago major, a selective inhibitor of cyclooxygenase-2 catalyzed prostaglandin biosynthesis.
Topics: Animals; Cattle; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; In Vitro Techniques; Isoenzymes; Plantago; Plants, Medicinal; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sheep; Triterpenes; Ursolic Acid | 1998 |
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes.
Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis | 1999 |
Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta.
Topics: Amino Acid Sequence; Animals; Anion Transport Proteins; Biological Transport; Carrier Proteins; Cloning, Molecular; Dehydroepiandrosterone Sulfate; Estrone; Humans; Kidney; Kinetics; Membrane Proteins; Molecular Sequence Data; Ochratoxins; Oocytes; Placenta; RNA, Messenger; Sequence Alignment; Sulfates; Xenopus | 2000 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1.
Topics: Adenine; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Biological Transport; Carrier Proteins; Humans; Kidney; Organophosphonates; Structure-Activity Relationship | 2000 |
Interaction between methotrexate and nonsteroidal anti-inflammatory drugs in organic anion transporter.
Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Carrier Proteins; Kinetics; Methotrexate; Oocytes; Probenecid; Uricosuric Agents; Xenopus laevis | 2000 |
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; Gene Library; Humans; Kidney Tubules, Proximal; Molecular Sequence Data; Oocytes; Organic Anion Transporters, Sodium-Independent; Sequence Homology, Amino Acid; Tissue Distribution; Transfection; Xenopus laevis | 2001 |
Comparative inhibitory effects of different compounds on rat oatpl (slc21a1)- and Oatp2 (Slc21a5)-mediated transport.
Topics: Algorithms; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antitubercular; Antimalarials; Biological Transport, Active; Digoxin; Enzyme Inhibitors; Estradiol; Ibuprofen; LLC-PK1 Cells; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Quinidine; Quinine; Rats; Rifampin; Swine | 2002 |
Characterization of methotrexate transport and its drug interactions with human organic anion transporters.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cells, Cultured; Humans; Indomethacin; Kinetics; Liver-Specific Organic Anion Transporter 1; Methotrexate; Mice; Mice, Transgenic; Nerve Tissue Proteins; Organic Anion Transporters, Sodium-Independent; Phenylbutazone; Potassium Channels; Potassium Channels, Tandem Pore Domain; Probenecid | 2002 |
The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs.
Topics: Adenosine Triphosphate; Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cell Line; Cell Membrane; Diffusion; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Humans; Insecta; Multidrug Resistance-Associated Proteins; Prostaglandins; Prostaglandins A; Prostaglandins F; Ribosomal Proteins; RNA Interference; RNA, Small Interfering; Thromboxane B2; Time Factors | 2003 |
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caco-2 Cells; Cell Membrane Permeability; Heterocyclic Compounds; Humans; Protein Transport | 2003 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Synthesis and pharmacological evaluation of amide conjugates of NSAIDs with L-cysteine ethyl ester, combining potent antiinflammatory and antioxidant properties with significantly reduced gastrointestinal toxicity.
Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cholesterol; Cysteine; Drug Evaluation; Gastrointestinal Diseases; Lipoproteins, LDL; Mice; Rats; Triglycerides | 2004 |
Novel cyclooxygenase-1 inhibitors discovered using affinity fingerprints.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Combinatorial Chemistry Techniques; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Design; Drug Evaluation, Preclinical; Ibuprofen; Inhibitory Concentration 50; Isoenzymes; Models, Molecular; Models, Theoretical; Molecular Structure; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Quantitative Structure-Activity Relationship | 2004 |
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism | 2005 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Novel nonsteroidal antiinflammatory drugs possessing a nitric oxide donor diazen-1-ium-1,2-diolate moiety: design, synthesis, biological evaluation, and nitric oxide release studies.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Azo Compounds; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Esters; Guinea Pigs; Ibuprofen; In Vitro Techniques; Indomethacin; Membrane Proteins; Nitric Oxide; Nitric Oxide Donors; Prodrugs; Prostaglandin-Endoperoxide Synthases; Pyrrolidines; Rats; Stomach Ulcer; Structure-Activity Relationship | 2005 |
Expanding the ChemGPS chemical space with natural products.
Topics: Biological Products; Combinatorial Chemistry Techniques; Computer Graphics; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship | 2005 |
The geminal dimethyl analogue of Flurbiprofen as a novel Abeta42 inhibitor and potential Alzheimer's disease modifying agent.
Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cyclooxygenase Inhibitors; Disease Models, Animal; Flurbiprofen; Mice; Peptide Fragments | 2006 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Non-carboxylic analogues of arylpropionic acids: synthesis, anti-inflammatory activity and ulcerogenic potential.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Flurbiprofen; Ibuprofen; Male; Naproxen; Propionates; Rats; Stomach Ulcer; Structure-Activity Relationship; Thiadiazoles; Thiazoles | 2007 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
O2-acetoxymethyl-protected diazeniumdiolate-based NSAIDs (NONO-NSAIDs): synthesis, nitric oxide release, and biological evaluation studies.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme Activation; Methylation; Molecular Structure; Nitric Oxide; Oleic Acid; Oxygen; Rats; Sheep; Stomach Ulcer; Structure-Activity Relationship | 2007 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
NSAIDs revisited: putative molecular basis of their interactions with peroxisome proliferator-activated gamma receptor (PPARgamma).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Catalytic Domain; Computational Biology; Drug Design; Ligands; Models, Molecular; PPAR gamma; Protein Conformation; Software | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Synthesis and pharmacological investigation of 3-(substituted 1-phenylethanone)-4-(substituted phenyl)-1, 2, 3, 4-tetrahydropyrimidine-5-carboxylates.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Blood Pressure; Edema; Hypertension; Inflammation; Male; Mice; Pain Measurement; Pyrimidines; Rats; Stomach; Ulcer | 2009 |
Dinitroglyceryl and diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of aspirin, indomethacin and ibuprofen: synthesis, biological evaluation and nitric oxide release studies.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Drug Design; Humans; Ibuprofen; Indomethacin; Nitric Oxide; Nitric Oxide Donors; Prodrugs; Rats; Sheep | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Synthesis and evaluation of paracetamol esters as novel fatty acid amide hydrolase inhibitors.
Topics: Amidohydrolases; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Benzoates; Cell Line, Tumor; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Inhibitors; Inhibitory Concentration 50; Kinetics; Magnetic Resonance Spectroscopy; Polyunsaturated Alkamides; Pyridines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Spectrophotometry, Infrared; Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Design, synthesis, and biological evaluation of a novel class of gamma-secretase modulators with PPARgamma activity.
Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Caproates; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; Cricetulus; Cyclooxygenase Inhibitors; Drug Design; Humans; Peptide Fragments; PPAR gamma; Pyrimidines; Receptors, Notch; Sheep; Structure-Activity Relationship; Transcriptional Activation | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence | 2010 |
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney | 2011 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
Ethanesulfohydroxamic acid ester prodrugs of nonsteroidal anti-inflammatory drugs (NSAIDs): synthesis, nitric oxide and nitroxyl release, cyclooxygenase inhibition, anti-inflammatory, and ulcerogenicity index studies.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase Inhibitors; Edema; Esters; Gastric Mucosa; Humans; Hydroxamic Acids; Ibuprofen; Indomethacin; Male; Naproxen; Nitric Oxide Donors; Nitrogen Oxides; Prodrugs; Rats; Rats, Sprague-Dawley; Stereoisomerism; Stomach Ulcer; Structure-Activity Relationship | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
SAR studies of acidic dual γ-secretase/PPARγ modulators.
Topics: Amyloid Precursor Protein Secretases; Animals; Caproates; Cell Survival; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Conformation; PPAR gamma; Recombinant Proteins; Sheep; Stereoisomerism; Structure-Activity Relationship | 2011 |
Nitric oxide release is not required to decrease the ulcerogenic profile of nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Binding Sites; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Edema; Humans; Ibuprofen; Indomethacin; Nitric Oxide; Nitric Oxide Donors; Peptic Ulcer; Phenylethyl Alcohol; Prodrugs; Rats; Recombinant Proteins; Structure-Activity Relationship | 2012 |
Synthesis of novel 2-mercapto benzothiazole and 1,2,3-triazole based bis-heterocycles: their anti-inflammatory and anti-nociceptive activities.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzothiazoles; Click Chemistry; Cyclooxygenase Inhibitors; Edema; Female; Humans; Male; Models, Molecular; Nociception; Rats; Rats, Wistar; Triazoles | 2012 |
Design and synthesis of thiourea derivatives containing a benzo[5,6]cyclohepta[1,2-b]pyridine moiety as potential antitumor and anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Biological Assay; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclization; Disease Models, Animal; Drug Design; Female; Humans; Inhibitory Concentration 50; Mice; Pyrimidines; Thiourea | 2012 |
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Synthesis and biological evaluation of cyanoguanidine derivatives of loratadine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Ear Diseases; Guanidines; HT29 Cells; Humans; Loratadine; Male; MCF-7 Cells; Mice; Mice, Inbred Strains; Molecular Structure; Structure-Activity Relationship; Xylenes | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Modified acidic nonsteroidal anti-inflammatory drugs as dual inhibitors of mPGES-1 and 5-LOX.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Cell Line; Humans; Indomethacin; Intramolecular Oxidoreductases; Lipoxygenase Inhibitors; Microsomes; Prostaglandin-E Synthases; Pyrazoles; Structure-Activity Relationship; Sulfonamides | 2012 |
Synthesis, pharmacological characterization, and docking analysis of a novel family of diarylisoxazoles as highly selective cyclooxygenase-1 (COX-1) inhibitors.
Topics: Animals; Blood Platelets; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Epoprostenol; Female; Fibrinolytic Agents; Furans; Humans; Isoxazoles; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet-Rich Plasma; Structure-Activity Relationship; Thromboxane A2 | 2013 |
Rotenoids from Boerhaavia diffusa as potential anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Female; Flavonoids; India; Molecular Structure; Nyctaginaceae; Plant Roots; Rats; Rats, Sprague-Dawley; Rotenone | 2013 |
High analgesic and anti-inflammatory in vivo activities of six new hybrids NSAIAs tetrahydropyran derivatives.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Mice; Molecular Structure; Motor Activity; Pyrans | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Synthesis, biological evaluation, molecular docking and theoretical evaluation of ADMET properties of nepodin and chrysophanol derivatives as potential cyclooxygenase (COX-1, COX-2) inhibitors.
Topics: Absorption, Physicochemical; Animals; Anthraquinones; Catalytic Domain; Chemistry Techniques, Synthetic; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Female; Inhibitory Concentration 50; Molecular Docking Simulation; Naphthalenes; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2014 |
Benzimidazole--ibuprofen/mesalamine conjugates: potential candidates for multifactorial diseases.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Benzimidazoles; Edema; Ibuprofen; Immunomodulation; Mesalamine; Mice; Molecular Structure; Neoplasms; Rats; Rats, Wistar; Sheep | 2015 |
Inhibition of FAAH, TRPV1, and COX2 by NSAID-serotonin conjugates.
Topics: Amidohydrolases; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Flurbiprofen; Humans; Serotonin; TRPV Cation Channels | 2014 |
Effect of new hybrids based on 5,16-pregnadiene scaffold linked to an anti-inflammatory drug on the growth of a human astrocytoma cell line (U373).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Humans; Molecular Structure; Pregnadienes; Sulindac; Time Factors | 2015 |
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics | 2015 |
Synthesis and Evaluation of Novel Erlotinib-NSAID Conjugates as More Comprehensive Anticancer Agents.
Topics: | 2015 |
Synthesis and biological evaluation of 1,3-diaryl pyrazole derivatives as potential antibacterial and anti-inflammatory agents.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Candida albicans; Drug Resistance, Multiple, Bacterial; Furans; Gram-Negative Bacteria; Gram-Positive Cocci; Ibuprofen; Indomethacin; Mice; Pyrazoles | 2015 |
Esters of some non-steroidal anti-inflammatory drugs with cinnamyl alcohol are potent lipoxygenase inhibitors with enhanced anti-inflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cinnamates; Edema; Esters; Glycine max; Hyperlipidemias; Indoleacetic Acids; Lipoxygenase Inhibitors; Polyethylene Glycols; Propanols; Propionates; Rats; Thioctic Acid | 2015 |
Amides of non-steroidal anti-inflammatory drugs with thiomorpholine can yield hypolipidemic agents with improved anti-inflammatory activity.
Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholesterol; Cholesterol, LDL; Edema; Hyperlipidemias; Hypolipidemic Agents; Morpholines; Rats; Triglycerides | 2016 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Synthesis and biological evaluation of chalcone derivatives containing aminoguanidine or acylhydrazone moieties.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Candida albicans; Cell Line; Cell Proliferation; Chalcone; Dose-Response Relationship, Drug; Guanidines; Humans; Hydrazones; Microbial Sensitivity Tests; Molecular Structure; Salmonella typhimurium; Structure-Activity Relationship | 2016 |
Synthesis and biological evaluation of novel podophyllotoxin-NSAIDs conjugates as multifunctional anti-MDR agents against resistant human hepatocellular carcinoma Bel-7402/5-FU cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Line; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Liver Neoplasms; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship | 2017 |
Anti-inflammatory 12,20-Epoxypregnane and 11,12-seco-Pregnane Glycosides from the Stems of Hoya kerrii.
Topics: Animals; Anti-Inflammatory Agents; Apocynaceae; Crystallography, X-Ray; Cyclooxygenase 2; Dose-Response Relationship, Drug; Glycosides; Inhibitory Concentration 50; Lipopolysaccharides; Macrophages; Mice; Molecular Conformation; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase Type II; Nuclear Magnetic Resonance, Biomolecular; Plant Stems; Pregnanes; Thailand | 2017 |
Design, synthesis, anti-inflammatory activity, and molecular docking studies of perimidine derivatives containing triazole.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytokines; Dose-Response Relationship, Drug; Drug Design; Mice; Molecular Docking Simulation; Molecular Structure; Quinazolines; RAW 264.7 Cells; Structure-Activity Relationship; Triazoles | 2017 |
Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates.
Topics: Acetylcholinesterase; Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Drug Discovery; Hep G2 Cells; Humans; Hydrazones; Indans; Models, Molecular; Molecular Structure; Neuroprotective Agents; Piperidines; Structure-Activity Relationship | 2018 |
Synthesis and biological properties of aryl methyl sulfones.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Carrageenan; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Edema; Humans; Male; Mice; Models, Molecular; Molecular Structure; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Structure-Activity Relationship; Sulfones; Thermodynamics | 2018 |
Synthesis, pharmacological profile and 2D-QSAR studies of curcumin-amino acid conjugates as potential drug candidates.
Topics: Amino Acids; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Candida albicans; Carrageenan; Cell Proliferation; Curcumin; Dose-Response Relationship, Drug; Edema; Mice; Microbial Sensitivity Tests; Molecular Structure; Pain; Pseudomonas aeruginosa; Quantitative Structure-Activity Relationship; Rats; Salmonella typhi; Spleen; Staphylococcus aureus; Streptococcus pyogenes; Ulcer | 2020 |
Synthesis and anticancer activity of open-resorcinarene conjugates.
Topics: Animals; Antineoplastic Agents; Calixarenes; Cell Line, Tumor; Cell Proliferation; Chlorocebus aethiops; COS Cells; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Phenylalanine; Structure-Activity Relationship | 2020 |
"Clickable" Albumin Binders for Modulating the Tumor Uptake of Targeted Radiopharmaceuticals.
Topics: Albumins; Animals; Copper Radioisotopes; Lysine; Mice; Neoplasms; Positron-Emission Tomography; Protein Binding; Radiopharmaceuticals; Structure-Activity Relationship; Tissue Distribution; Xenograft Model Antitumor Assays | 2022 |
Small molecule NSAID derivatives for impairing powerhouse in cancer cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Ibuprofen; Indomethacin; Mitochondria; Neoplasms; Reactive Oxygen Species | 2022 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Analgesic drugs in the management of pain.
Topics: Analgesics; Anti-Anxiety Agents; Aspirin; Carbamazepine; Codeine; Dextropropoxyphene; Humans; Hypnotics and Sedatives; Ibuprofen; Indomethacin; Methadone; Morphine; Oxycodone; Pain; Pain, Intractable; Pentazocine; Pyrazoles | 1977 |
Prostaglandin synthetase systems in rat and rabbit renal medulla and inhibition by non-steroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Ibuprofen; Indomethacin; Ketoprofen; Kidney; Kidney Medulla; Male; Microsomes; Phenylbutazone; Prostaglandins E; Prostaglandins F; Rabbits; Rats | 1977 |
Effects of some anti-rheumatic agents on copper-catalyzed thermal aggregation of gamma globulin.
Topics: Anti-Inflammatory Agents; Aspirin; Copper; Dexamethasone; Diclofenac; Flufenamic Acid; gamma-Globulins; Gold Sodium Thiomalate; Hot Temperature; Humans; Ibuprofen; Indans; Indomethacin; Penicillamine; Phenylbutazone; Prednisolone | 1979 |
Flurbiprofen: highly potent inhibitor of prostaglandin synthesis.
Topics: Animals; Arachidonic Acids; Aspirin; Cattle; Cyclooxygenase Inhibitors; Flurbiprofen; Ibuprofen; Indomethacin; Male; Microsomes; Oxygen Consumption; Phenylbutazone; Propionates; Prostaglandins E; Seminal Vesicles | 1978 |
Inhibition of ferrous iron induced oxidation of arachidonic acid by indomethacin.
Topics: Arachidonic Acids; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ferrous Compounds; Ibuprofen; Indomethacin; Iron; Models, Chemical; Nitroblue Tetrazolium; Oxidation-Reduction; Tolmetin | 1979 |
Characterization of inhibitor(s) of lymphocyte activation in serum from rats with adjuvant arthritis.
Topics: Animals; Arthritis; Arthritis, Experimental; Chemical Fractionation; Chromatography, Gel; Concanavalin A; Female; Ibuprofen; Indomethacin; Lymph Nodes; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Penicillamine; Phenylbutazone; Phytohemagglutinins; Rats; Spleen | 1978 |
Chemotactic factor-induced generation of superoxide radicals by human neutrophils: effect of metabolic inhibitors and antiinflammatory drugs.
Topics: 6-Aminonicotinamide; Anti-Inflammatory Agents; Antimetabolites; Aspirin; Aurothioglucose; Chemotaxis, Leukocyte; Deoxyglucose; Dose-Response Relationship, Drug; Ethylmaleimide; Free Radicals; Glycolysis; Humans; Hydrocortisone; Ibuprofen; Indomethacin; Iodoacetates; Neutrophils; Ouabain; Oxygen; Phenylbutazone; Superoxides | 1979 |
The prostaglandin and kallikrein-kinin systems in mineralocorticoid escape.
Topics: Adult; Aldosterone; Desoxycorticosterone; Humans; Ibuprofen; Indomethacin; Kallikreins; Kinins; Male; Middle Aged; Potassium; Prostaglandins E; Sodium | 1978 |
Nonsteroidal antiinflammatory agents.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Child, Preschool; Humans; Ibuprofen; Indomethacin; Infant; Phenylbutazone; Tolmetin | 1977 |
Action of nonsteroidal, anti-inflammatory drugs on human and rat peripheral leucocyte migration in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Migration Inhibition; Cell Movement; Dose-Response Relationship, Drug; Humans; Ibuprofen; Indomethacin; Leukocytes; Phenylbutazone; Rats; Sodium Salicylate | 1977 |
Salicylate-induced enzymuria: comparison with other anti-inflammatory agents.
Topics: Acetaminophen; Acetylglucosaminidase; Adult; Anti-Inflammatory Agents; Aspirin; Gold; Hexosaminidases; Humans; Ibuprofen; Indomethacin; Kidney; Kidney Diseases; Lysosomes; Rheumatic Diseases; Salicylates | 1978 |
Correlations of DNA, RNA and protein levels in duodenal mucosa with antiinflammatory potency and disposition to gut damage of non-steroidal agents. Comparative behaviour of glucametacine, indometacin, phenylbutazone and ibuprofen.
Topics: Animals; Anti-Inflammatory Agents; DNA; Duodenal Ulcer; Duodenum; Female; Gastrointestinal Hemorrhage; Glucosamine; Ibuprofen; Indomethacin; Intestinal Mucosa; Male; Phenylbutazone; Proteins; Rats; RNA | 1978 |
Effects of prostaglandin synthesis inhibitors on human insulin secretion and carbohydrates tolerance.
Topics: Adult; Aspirin; Blood Glucose; Dose-Response Relationship, Drug; Glucose Tolerance Test; Humans; Ibuprofen; Indomethacin; Insulin; Insulin Secretion; Male; Middle Aged; Prostaglandin Antagonists; Prostaglandins E; Secretory Rate; Sodium Salicylate | 1979 |
The effect of immunosuppressive and anti-inflammatory drugs on lymphocyte population and MIF in glomerulonephritis.
Topics: Azathioprine; B-Lymphocytes; Cell Migration Inhibition; Glomerulonephritis; Humans; Ibuprofen; Immunosuppressive Agents; Indomethacin; Leukocyte Migration-Inhibitory Factors; Lymphokines; Prednisone; Rosette Formation; T-Lymphocytes | 1979 |
Studies on the experimental therapy of iridocyclitis.
Topics: Animals; Anti-Inflammatory Agents; Aqueous Humor; Disease Models, Animal; Female; Hydrocortisone; Ibuprofen; Indomethacin; Male; Mercaptopurine; Orosomucoid; Peptide Hydrolases; Prostaglandins; Proteins; Rabbits; Sialic Acids; Uveitis, Anterior | 1979 |
Potentiation of PG effects on the intraocular muscles of the cat by inhibition of PG synthesis.
Topics: Animals; Cats; Ciliary Body; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Flurbiprofen; Ibuprofen; In Vitro Techniques; Indomethacin; Iris; Mixed Function Oxygenases; Muscle Contraction; Muscle, Smooth; Prostaglandins; Prostaglandins E; Prostaglandins F | 1977 |
Influence of nonsteroidal anti-inflammatory drugs on ouabain toxicity.
Topics: Animals; Anti-Inflammatory Agents; Arrhythmias, Cardiac; Aspirin; Cyclooxygenase Inhibitors; Dogs; Female; Ibuprofen; Indomethacin; Male; Ouabain; Prostaglandin Antagonists; Tachycardia; Ventricular Fibrillation | 1977 |
Prostaglandin synthetase inhibitors in Bartter's syndrome. Effect on immunoreactive prostaglandin E excretion.
Topics: Adolescent; Adult; Aldosterone; Aspirin; Bartter Syndrome; Blood Pressure; Child; Cyclooxygenase Inhibitors; Female; Humans; Hyperaldosteronism; Ibuprofen; Indomethacin; Kidney; Middle Aged; Prostaglandins E; Renin | 1978 |
Prostaglandins: modulators of renal function and pressor resistance in chronic liver disease.
Topics: Adult; Aldosterone; Ascites; Chronic Disease; Creatinine; Female; Humans; Ibuprofen; Indomethacin; Kidney; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Prostaglandins E; Renin; Sodium | 1979 |
Regulation of urinary prostaglandins in Bartter's syndrome.
Topics: Adult; Bartter Syndrome; Humans; Hyperaldosteronism; Hypokalemia; Ibuprofen; Indomethacin; Magnesium; Potassium; Prostaglandins E; Water | 1979 |
Inhibition of human leucocytes locomotion by anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Cell Movement; Chemotaxis, Leukocyte; Depression, Chemical; Humans; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Neutrophils; Salicylates | 1979 |
Indomethacin-induced inhibition of prostaglandin with hyperkalemia.
Topics: Aldosterone; Humans; Hyperkalemia; Ibuprofen; Indomethacin; Kidney; Male; Mineralocorticoid Receptor Antagonists; Potassium; Prostaglandin Antagonists; Renin | 1979 |
Drugs for dysmenorrhea.
Topics: Acetaminophen; Aspirin; Dysmenorrhea; Female; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Nalbuphine; Naproxen; Time Factors | 1979 |
Escape from sodium and potassium retaining actions of aspirin-like drugs used in a patient with Bartter's syndrome.
Topics: Adult; Anti-Inflammatory Agents; Aspirin; Bartter Syndrome; Humans; Hyperaldosteronism; Ibuprofen; Indomethacin; Male; Potassium; Prostaglandins; Sodium; Spironolactone | 1979 |
The role of direct tissue contact in the production of gastrointestinal ulcers by anti-inflammatory drugs in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Female; Ibuprofen; Indomethacin; Injections, Intravenous; Male; Peptic Ulcer; Phenylbutazone; Rats | 1979 |
[A clinical study of pathophysiological feature of "Bartter's syndrome" (author's transl)].
Topics: Adult; Angiotensin II; Aspirin; Bartter Syndrome; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Electrolytes; Female; Humans; Hyperaldosteronism; Hypokalemia; Ibuprofen; Indomethacin; Infant; Male; Renin; Water-Electrolyte Balance | 1979 |
Comparisons of tolerability findings in international clinical trials.
Topics: Arthritis, Rheumatoid; Aspirin; Cardiovascular System; Clinical Trials as Topic; Diclofenac; Drug Tolerance; Follow-Up Studies; Gastrointestinal Diseases; Hematologic Tests; Humans; Ibuprofen; Indomethacin; International Cooperation; Naproxen; Phenylacetates; Time Factors | 1979 |
[Irritative activity of a new anti-inflammatory agent 4-(p-chorophenyl)-2-phenyl-5-thiazoleacetic acid (CH-800) on the gastrointestinal tract in rats (author's transl)].
Topics: Acetates; Administration, Oral; Animals; Anti-Inflammatory Agents; Aspirin; Diclofenac; Digestive System; Ibuprofen; Indomethacin; Irritants; Male; Phenylbutazone; Rats; Stomach Ulcer; Thiazoles | 1979 |
Nonsteroid anti-inflammatory drugs in the treatment of immunologic iridocyclitis in the rabbit.
Topics: Animals; Anti-Inflammatory Agents; Aqueous Humor; Female; Ibuprofen; Indomethacin; Male; Orosomucoid; Oxyphenbutazone; Proteins; Rabbits; Sialic Acids; Sodium Salicylate; Uveitis, Anterior | 1977 |
Pharmacologic studies in Bartter's syndrome: opposite effects of treatment with antikaliuretic and antiprostaglandin drugs. Part I.
Topics: Adult; Amiloride; Bartter Syndrome; Humans; Hyperaldosteronism; Ibuprofen; Indomethacin; Male; Potassium; Propranolol; Prostaglandin Antagonists; Renin; Sodium; Spironolactone; Time Factors | 1978 |
Sigma SR, a new method of measuring erythrocyte sedimentation rate. Its value in studying the action and interactions of non-steroidal anti-inflammatory agents.
Topics: Adult; Aged; Anti-Inflammatory Agents; Aspirin; Blood Sedimentation; Body Temperature; Drug Interactions; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged | 1978 |
[Antirheumatic non-steroid drugs in the treatment of rheumatoid arthritis].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Drug Evaluation; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Phenylbutazone | 1978 |
Nonsteroidal anti-inflammatory drug treatment for arthritis.
Topics: Anti-Inflammatory Agents; Arthritis; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Naproxen; Oxyphenbutazone; Phenylbutazone; Salicylates | 1978 |
Bioavailability of powdered inclusion compounds of nonsteroidal antiinflammatory drugs with beta-cyclodextrin in rabbits and dogs.
Topics: Animals; Anti-Inflammatory Agents; Biological Availability; Dextrins; Dogs; Flufenamic Acid; Ibuprofen; Indomethacin; Ketoprofen; Powders; Rabbits; Starch | 1978 |
A clinical trial of indomethacin and ibuprofen in dysmenorrhea.
Topics: Adolescent; Adult; Dysmenorrhea; Female; Humans; Ibuprofen; Indomethacin | 1978 |
Rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Aspirin; Aurothioglucose; Cyclophosphamide; Female; Gold Sodium Thiomalate; Humans; Hydroxychloroquine; Ibuprofen; Immunosuppressive Agents; Indomethacin; Middle Aged; Phenylbutazone; Physical Therapy Modalities; Prednisolone; Referral and Consultation | 1975 |
Bartter's syndrome: a disorder characterized by high urinary prostaglandins and a dependence of hyperreninemia on prostaglandin synthesis.
Topics: Adolescent; Adult; Aldosterone; Bartter Syndrome; Blood Pressure; Female; Humans; Hyperaldosteronism; Ibuprofen; Indomethacin; Kidney; Middle Aged; Potassium; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostaglandins E; Prostaglandins F; Renin; Sodium | 1976 |
Prostaglandin synthetase activity from human rheumatoid synovial microsomes. Effect of 'aspirin-like' drug therapy.
Topics: Adult; Aged; Arachidonic Acids; Arthritis, Rheumatoid; Aspirin; Cyclooxygenase Inhibitors; Female; Humans; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Microsomes; Middle Aged; Mixed Function Oxygenases; Naproxen; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Prostaglandins F; Synovial Membrane | 1976 |
Prostaglandins are overproduced by the kidneys and mediate hyperreninemia in Bartter's syndrome.
Topics: Adolescent; Adult; Aged; Aldosterone; Bartter Syndrome; Cyclooxygenase Inhibitors; Female; Humans; Hyperaldosteronism; Ibuprofen; Indomethacin; Kidney; Male; Middle Aged; Potassium; Prostaglandins E; Renin | 1976 |
Association of renal papillary necrosis and ankylosing spondylitis.
Topics: Adult; Humans; Ibuprofen; Indomethacin; Kidney Papillary Necrosis; Male; Phenylbutazone; Spondylitis, Ankylosing | 1977 |
Aspirin and newer anti-inflammatory agents in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Fenoprofen; Humans; Ibuprofen; Indomethacin; Naproxen; Peptic Ulcer; Phenylbutazone; Tolmetin | 1977 |
Prostaglandins and the control of muscle tone in the ductus arteriosus.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Ductus Arteriosus; Gestational Age; Glutathione; Hypoxia; Ibuprofen; Indomethacin; Muscle Contraction; Oxygen; Prostaglandins; Prostaglandins E; Prostaglandins F; Sheep; Species Specificity | 1977 |
Duodenal mucosal damage associated with chronic use of anti-inflammatory drugs.
Topics: Aged; Anti-Inflammatory Agents; Aspirin; Diclofenac; Duodenal Ulcer; Endoscopy; Female; Fiber Optic Technology; Gastritis; Humans; Ibuprofen; Indomethacin; Intestinal Mucosa; Male; Middle Aged | 1977 |
The treatment of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Child; Chloroquine; Female; Gold; Humans; Hydroxychloroquine; Ibuprofen; Indomethacin; Injections, Intra-Articular; Male; Penicillamine; Phenylbutazone; Physical Therapy Modalities; Pregnancy; Pregnancy Complications; Prognosis; Salicylates | 1977 |
Oral antipyretic therapy.
Topics: Acetaminophen; Administration, Oral; Aminopyrine; Aspirin; Child; Child, Preschool; Drug Evaluation; Fever; Humans; Ibuprofen; Indomethacin; Phenylpropionates | 1976 |
Some effects of non-steroidal anti-inflammatory drugs on leucocyte migration.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Cell Movement; Edema; Fenoprofen; Ibuprofen; Indomethacin; Ketoprofen; Leukocytes; Male; Methotrexate; Naproxen; Phenylbutazone; Pleurisy; Rats | 1976 |
Medical management of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Aspirin; Chloroquine; Gold; Humans; Ibuprofen; Indomethacin; Naproxen; Occupational Therapy; Phenylbutazone; Physical Therapy Modalities | 1976 |
In vivo suppression of prostaglandin biosynthesis by non-steroidal anti-inflammatory agents.
Topics: Acetaminophen; Acetonitriles; Administration, Oral; Animals; Anti-Inflammatory Agents; Brain; Duodenum; Female; Flurbiprofen; Gastric Mucosa; Ibuprofen; Indomethacin; Intestine, Small; Kidney; Liver; Lung; Prostaglandins E; Prostaglandins F; Radioimmunoassay; Rats; Time Factors | 1976 |
Effect of anti-inflammatory drugs on sulphated glycosaminoglycan synthesis in aged human articular cartilage.
Topics: Aged; Aging; Anti-Inflammatory Agents; Cartilage, Articular; Depression, Chemical; Flurbiprofen; Glycosaminoglycans; Humans; Hydrocortisone; Ibuprofen; In Vitro Techniques; Indomethacin; Middle Aged; Sodium Salicylate | 1976 |
Relationship between the inhibitory activity on 'RCS' and prostaglandins synthesis and the anti-inflammatory activity of ketoprofen and several other non-steroidal anti-inflammatory agents.
Topics: Abscess; Animals; Anti-Inflammatory Agents; Aorta; Arachidonic Acids; Aspirin; Benzophenones; Colon; Guinea Pigs; Hydroxy Acids; Ibuprofen; In Vitro Techniques; Indomethacin; Ketoprofen; Lung; Muscle Contraction; Naproxen; Phenylbutazone; Prostaglandin Antagonists; Prostaglandins; Pyrans | 1976 |
[Various problems of drug treatment of rheumatoid arthritis].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Butadienes; Drug Evaluation; Humans; Ibuprofen; Indomethacin | 1976 |
Structural requirements for time-dependent inhibition of prostaglandin biosynthesis by anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Fatty Acids; Flurbiprofen; Ibuprofen; Indomethacin; Kinetics; Meclofenamic Acid; Mefenamic Acid; Oxygen Consumption; Oxygenases; Prostaglandins; Structure-Activity Relationship | 1975 |
Rheumatic diseases. 2. Therapeutic considerations.
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Aspirin; Calcinosis; Carpal Tunnel Syndrome; Colchicine; Gout; Hip Joint; Humans; Ibuprofen; Indomethacin; Joint Prosthesis; Osteoarthritis; Phenylbutazone; Rheumatic Diseases; Spondylitis, Ankylosing; Tendinopathy | 1976 |
The aging skeleton. Osteoporosis and degenerative arthritis.
Topics: Age Factors; Aged; Aspirin; Estrogens; Female; Fracture Fixation; Humans; Ibuprofen; Indomethacin; Joint Prosthesis; Male; Osteoarthritis; Osteoporosis; Phenylbutazone; Sex Factors | 1975 |
The antagonism by anti-inflammatory analgesics of prostaglandin f 2 alpha-induced contractions of human and rabbit myometrium in vitro.
Topics: Abortion, Induced; Animals; Anti-Inflammatory Agents; Aspirin; Drug Antagonism; Female; Ibuprofen; Indomethacin; Mefenamic Acid; Myometrium; Phenylbutazone; Pregnancy; Pregnancy Trimester, Second; Prostaglandin Antagonists; Prostaglandins F; Rabbits; Stimulation, Chemical; Uterine Contraction; Uterus | 1975 |
[Evaluation of the effectiveness of antirheumatic preparations].
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Drug Evaluation; Female; Humans; Ibuprofen; Indomethacin; Joints; Male; Meprobamate; Methods; Middle Aged; Prednisolone; Sodium Salicylate | 1975 |
[New possibilities of pharmacotherapy in juvenile rheumatoid arthritis].
Topics: Adolescent; Anti-Inflammatory Agents; Arthritis, Juvenile; Child; Humans; Ibuprofen; Indomethacin | 1976 |
Activated neutrophils alter contractile properties of the pulmonary artery.
Topics: Animals; Catalase; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Methacrylates; Muscle Contraction; Muscle, Smooth, Vascular; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pulmonary Artery; Rats; Rats, Inbred Strains; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane-A Synthase | 1992 |
Human cyclooxygenase-2 cDNA.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Cell Line; Cells, Cultured; Cloning, Molecular; DNA; Endothelium, Vascular; Humans; Ibuprofen; Indomethacin; Kinetics; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection; Umbilical Veins | 1992 |
A sensitive and relevant model for evaluating anti-inflammatory activity-papaya latex-induced rat paw inflammation.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Disease Models, Animal; Ibuprofen; Indomethacin; Inflammation; Levamisole; Male; Papain; Piroxicam; Prednisolone; Rats; Triterpenes | 1992 |
Differential sensitivity of in vivo TNF and IL-6 production to modulation by anti-inflammatory drugs in mice.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Dose-Response Relationship, Drug; Ibuprofen; Indomethacin; Interleukin-6; Lipopolysaccharides; Male; Mice; Tumor Necrosis Factor-alpha | 1992 |
Dissociation between prostaglandin levels and blood flow to the retina and choroid in the newborn pig after nonsteroidal antiinflammatory drugs.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Choroid; Ibuprofen; Indomethacin; Naproxen; Osmolar Concentration; Prostaglandins; Regional Blood Flow; Retina; Retinal Vessels; Swine | 1992 |
Nonsteroidal anti-inflammatory drug toxicosis in dogs and cats: 240 cases (1989-1990)
Topics: Accidents; Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cat Diseases; Cats; Dog Diseases; Dogs; Gastrointestinal Diseases; Ibuprofen; Indomethacin; Poisoning; Retrospective Studies | 1992 |
Effects of different cyclooxygenase inhibitors on the segmental distribution of pulmonary vascular resistance in the dog.
Topics: Animals; Dogs; Female; Ibuprofen; Indomethacin; Lung; Male; Meclofenamic Acid; Pulmonary Circulation; Vascular Resistance; Vasoconstriction | 1992 |
Phospholipase-A2 action and arachidonic acid metabolism in calcium-mediated parathyroid hormone secretion.
Topics: Acetophenones; Animals; Arachidonic Acid; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Flavanones; Flavonoids; Ibuprofen; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Parathyroid Glands; Parathyroid Hormone; Phospholipases A; Phospholipases A2; Pyrazoles; Quinacrine; Swine; Time Factors; Tritium | 1992 |
Shear-induced platelet-derived growth factor gene expression in human endothelial cells is mediated by protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Cells, Cultured; Egtazic Acid; Endothelium, Vascular; Gene Expression Regulation; Guanosine Diphosphate; Humans; Ibuprofen; Indomethacin; Isoquinolines; Neomycin; Piperazines; Platelet-Derived Growth Factor; Protein Kinase C; RNA, Messenger; Signal Transduction; Staurosporine; Stress, Mechanical; Sulfonamides; Transcriptional Activation | 1992 |
A comparison of indomethacin with ibuprofen on gastrointestinal mucosal integrity in conventional and germ-free rats.
Topics: Animals; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Germ-Free Life; Ibuprofen; Indomethacin; Intestinal Diseases; Intestinal Mucosa; Male; Rats; Ulcer | 1992 |
Influence of NSAID-induced inhibition of renal prostaglandin synthesis on inorganic sulfate clearance in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Ibuprofen; Indomethacin; Kidney; Metabolic Clearance Rate; Prostaglandins; Rats; Rats, Inbred Lew; Sulfates | 1992 |
Triggering by ATP of product release by mucous granules of the land slug Ariolimax columbianus.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Calcimycin; Cytoplasmic Granules; Dinoprostone; Electric Stimulation; Ethylmaleimide; Furosemide; Ibuprofen; Indomethacin; Kinetics; Microscopy, Electron; Mollusca; Mucous Membrane; Nigericin; Pertussis Toxin; Tetradecanoylphorbol Acetate; Verapamil; Virulence Factors, Bordetella | 1992 |
Ionic, electrical, and secretory effects of inhibitors of arachidonic acid metabolism in mouse pancreatic beta-cells.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acids; Aspirin; Calcium; Cell Membrane Permeability; Cells, Cultured; Cyclooxygenase Inhibitors; Electric Conductivity; Female; Glucose; Hydrogen-Ion Concentration; Ibuprofen; Indomethacin; Insulin; Islets of Langerhans; Lipoxygenase Inhibitors; Membrane Potentials; Mice; Microelectrodes; Potassium; Potassium Channels; Radioimmunoassay; Rubidium Radioisotopes; Sodium Salicylate | 1992 |
Immunotherapy of mammary adenocarcinoma metastases in C3H/HeN mice with chronic administration of cyclo-oxygenase inhibitors alone or in combination with IL-2.
Topics: Adenocarcinoma; Animals; Cell Division; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Female; Ibuprofen; Immunotherapy; Indomethacin; Interleukin-3; Killer Cells, Natural; Lung Neoplasms; Lymphocytes; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Neoplasm Metastasis; Neoplasm Transplantation; Phenotype; Spleen | 1992 |
Ibuprofen, indomethacin, and high-dose aspirin, but not low-dose aspirin or imidazole, inhibit CGRP elevations in plasma during endotoxicosis.
Topics: Animals; Aspirin; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; Endotoxins; Ibuprofen; Imidazoles; Indomethacin; Rats; Reference Values; Salmonella enteritidis; Shock, Septic | 1992 |
PGF2 alpha synthesis in isolated cerebellar glomeruli: effects of membrane depolarization, calcium availability and phospholipase activity.
Topics: Animals; Calcimycin; Calcium; Calcium Channel Blockers; Cerebellum; Dinoprost; Dinoprostone; Ibuprofen; Indomethacin; Kinetics; Male; Masoprocol; Membrane Potentials; Phospholipases; Potassium; Rats; Rats, Inbred Strains; Sodium Channels; Synapses; Veratridine | 1991 |
Influence of the anti-inflammatory compound flosulide on granulocyte function.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemotaxis; Ibuprofen; Indans; Indomethacin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Piroxicam; Sulfonamides; Superoxides | 1991 |
[Antiinflammatory drugs inhibit the elevation of plasma CGRP concentration in endotoxin shock in rats].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcitonin Gene-Related Peptide; Ibuprofen; Indomethacin; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Shock, Septic | 1991 |
Suspected central nervous system toxicity from inadvertent nonsteroidal antiinflammatory drug overdose.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Central Nervous System Diseases; Diclofenac; Drug Overdose; Female; Humans; Ibuprofen; Indomethacin; Middle Aged; Poisoning | 1991 |
[Effect of drugs inhibiting prostaglandin activity on the appearance of leukocytes in the tears after experimental injury to the corneal epithelium].
Topics: Animals; Chemotaxis, Leukocyte; Corneal Injuries; Disease Models, Animal; Epithelium; Female; Ibuprofen; Indomethacin; Leukocyte Count; Leukocytes; Male; Prostaglandin Antagonists; Rabbits; Tears; Time Factors | 1991 |
Effect of sodium lauryl sulfate-induced skin irritation on in vitro percutaneous absorption of four drugs.
Topics: Acitretin; Administration, Cutaneous; Administration, Topical; Animals; Anti-Inflammatory Agents; Body Water; Dermatitis, Contact; Female; Guinea Pigs; Hydrocortisone; Ibuprofen; Indomethacin; Skin Absorption; Sodium Dodecyl Sulfate; Tretinoin | 1991 |
Effect of sodium lauryl sulfate-induced skin irritation on in vivo percutaneous penetration of four drugs.
Topics: Acitretin; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dermatitis, Contact; Female; Guinea Pigs; Hydrocortisone; Ibuprofen; Indomethacin; Skin; Skin Absorption; Sodium Dodecyl Sulfate; Tretinoin | 1991 |
Tenidap, in contrast to several available nonsteroidal antiinflammatory drugs, potently inhibits the release of activated neutrophil collagenase.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Hypochlorous Acid; Ibuprofen; In Vitro Techniques; Indoles; Indomethacin; Microbial Collagenase; Naproxen; Neutrophils; Oxindoles; Peroxidase; Piroxicam; Reference Values; Superoxides | 1991 |
Effects of some nonsteroidal anti-inflammatory agents on experimental radiation pneumonitis.
Topics: Acetophenones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diethylcarbamazine; Ibuprofen; Indomethacin; Mice; Piroxicam; Pneumonia; Radiation Injuries, Experimental; Tetrazoles | 1991 |
Differences in the effects in the newborn piglet of various nonsteroidal antiinflammatory drugs on cerebral blood flow but not on cerebrovascular prostaglandins.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cerebrovascular Circulation; Ibuprofen; Indomethacin; Naproxen; Prostaglandins; Swine | 1991 |
[Inhibition of thrombocyte function by non-steroidal anti-rheumatic agents: a comparative study between diclofenac, acemetacin, mefenamic acid and ibuprofen].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Cyclooxygenase Inhibitors; Diclofenac; Humans; Ibuprofen; Indomethacin; Malondialdehyde; Mefenamic Acid; Platelet Aggregation; Thromboxanes | 1991 |
Management of IUD-associated menorrhagia in female rhesus monkeys (Macaca mulatta).
Topics: Aminocaproic Acid; Animals; Anti-Inflammatory Agents; Antifibrinolytic Agents; Endometrium; Female; Ibuprofen; Indomethacin; Intrauterine Devices; Iron; Macaca mulatta; Menorrhagia; Menstrual Cycle; Menstruation; Naproxen; Plant Extracts; Tissue Plasminogen Activator; Tranexamic Acid | 1991 |
Cyclooxygenase inhibitors prevent ethchlorvynol-induced injury in rat and rabbit lungs.
Topics: Animals; Capillary Permeability; Cyclooxygenase Inhibitors; Ethchlorvynol; Ibuprofen; In Vitro Techniques; Indomethacin; Lung Diseases; Male; Meclofenamic Acid; Pulmonary Circulation; Rabbits; Rats; Rats, Inbred Strains; Vascular Resistance | 1991 |
The role of prostaglandin E2 in immune suppression following injury.
Topics: Adolescent; Adult; Aged; Burns; Dinoprostone; Endotoxins; Escherichia coli; Female; Humans; Ibuprofen; Immune Tolerance; Indomethacin; Interleukin-2; Leukocytes, Mononuclear; Male; Middle Aged | 1991 |
An ibuprofen-antagonized plasmin inhibitor released by human endothelial cells.
Topics: Antifibrinolytic Agents; Burns; Cells, Cultured; Cicatrix; Endothelium; Fibrinolysis; Hot Temperature; Humans; Ibuprofen; In Vitro Techniques; Indomethacin; Skin; Thrombosis; Tolmetin | 1991 |
Xenobiotic triacylglycerol formation in isolated hepatocytes.
Topics: Animals; Benzoates; Biotransformation; Fatty Acids; Female; Glycerol; Ibuprofen; Indomethacin; Male; Phenylbutyrates; Phytanic Acid; Rats; Triglycerides; Xenobiotics | 1991 |
Pattern of rheumatic diseases in south India. IV. Clinical profile of juvenile rheumatoid arthritis.
Topics: Arthritis, Juvenile; Aspirin; Child; Chronic Disease; Female; Humans; Ibuprofen; India; Indomethacin; Male | 1990 |
A method to predict the percutaneous permeability of various compounds: shed snake skin as a model membrane.
Topics: Animals; Cell Membrane Permeability; Hydrocortisone; Ibuprofen; Indomethacin; Ketoprofen; Models, Biological; Molecular Weight; Naproxen; Particle Size; Progesterone; Skin; Snakes | 1990 |
Effects of commonly used NSAID's on gastric mucosa. A clinico-endoscopic and histopathological study.
Topics: Acetaminophen; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Gastric Mucosa; Gastritis; Gastroscopy; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Oxyphenbutazone | 1990 |
Fatty acids and cyclooxygenase and lipoxygenase pathway inhibitors modulate inositol phosphate formation in pancreatic islets.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Carbachol; Dinoprostone; Glucose; Ibuprofen; Indomethacin; Inositol Phosphates; Islets of Langerhans; Lipoxygenase; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains | 1990 |
Reperfusion-induced arrhythmias are not prevented by ibuprofen in isolated rat heart.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arrhythmias, Cardiac; Coronary Circulation; Cyclooxygenase Inhibitors; Free Radicals; Heart Rate; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Myocardial Reperfusion Injury; Rats; Rats, Inbred Strains; Reperfusion | 1990 |
The prophylactic use of cyclooxygenase inhibitors in recurrent herpes simplex infections.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cyclooxygenase Inhibitors; Female; Herpes Simplex; Humans; Ibuprofen; Incidence; Indomethacin; Killer Cells, Natural; Male; Middle Aged; Recurrence | 1990 |
Prostanoids contribute to endothelium-dependent coronary vasodilation in guinea pigs.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Aorta, Abdominal; Coronary Vessels; Cyclooxygenase Inhibitors; Electric Stimulation; Endothelium, Vascular; Guinea Pigs; Ibuprofen; Indomethacin; Male; Nitroprusside; Prostaglandins; Vasoconstriction; Vasodilation | 1990 |
Transplacental cardiovascular effects of four popular analgesics in rats.
Topics: Acetaminophen; Analgesics; Animals; Aspirin; Cardiomegaly; Constriction, Pathologic; Ductus Arteriosus; Female; Fetal Heart; Heart Ventricles; Ibuprofen; Indomethacin; Maternal-Fetal Exchange; Pericardial Effusion; Pregnancy; Rats; Rats, Inbred Strains | 1990 |
Estimation of the in vivo effect of cyclooxygenase inhibitors on prostaglandin E2 levels in mouse brain.
Topics: Abdominal Muscles; Acetaminophen; Acetylcholine; Animals; Aspirin; Brain Chemistry; Brain Stem; Cerebral Cortex; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; Dinoprostone; Hypothalamus; Ibuprofen; Indomethacin; Male; Mice; Microsomes; Nociceptors; Pain Measurement; Prostaglandin-Endoperoxide Synthases | 1990 |
Indomethacin and ibuprofen inhibit the uptake of 45Ca2+ by washed human platelets through a thromboxane A2-independent mechanism.
Topics: Blood Platelets; Calcimycin; Calcium; Calcium Radioisotopes; Humans; Ibuprofen; In Vitro Techniques; Indomethacin; Thromboxane A2 | 1990 |
Biliary elimination of non-steroidal anti-inflammatory drugs in patients.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Bile; Cholestasis; Common Bile Duct Diseases; Diclofenac; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged | 1990 |
Oligohydramnios in each sac of a triplet gestation caused by Motrin--fulfilling Kock's postulates.
Topics: Adult; Amniotic Fluid; Female; Humans; Ibuprofen; Indomethacin; Obstetric Labor, Premature; Pregnancy; Pregnancy, Multiple; Renal Circulation; Tocolytic Agents; Triplets | 1990 |
Nonsteroidal anti-inflammatory drugs facilitate stone passage.
Topics: Humans; Ibuprofen; Indomethacin; Ureteral Calculi | 1990 |
Oligohydramnios associated with prostaglandin synthetase inhibitors in preterm labour.
Topics: Adult; Amniotic Fluid; Birth Weight; Female; Gestational Age; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Obstetric Labor, Premature; Pregnancy; Retrospective Studies; Risk Factors | 1990 |
Central effect of the non-steroid anti-inflammatory agents, indomethacin, ibuprofen, and diclofenac, determined in C fibre-evoked activity in single neurones of the rat thalamus.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Diclofenac; Dose-Response Relationship, Drug; Female; Ibuprofen; Indomethacin; Male; Nerve Fibers; Neurons; Rats; Rats, Inbred Strains; Thalamus | 1990 |
Objective assessment of topical corticosteroids and non-steroidal anti-inflammatory drugs in methyl-nicotinate-induced skin inflammation.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Betamethasone; Bufexamac; Clobetasol; Dermatitis, Contact; Diclofenac; Humans; Hydrocortisone; Ibuprofen; Indomethacin; Male; Nicotinic Acids; Niflumic Acid; Phenylbutazone; Regional Blood Flow; Skin | 1990 |
Melittin stimulates liver glycogenolysis and the release of prostaglandin D2 and thromboxane B2.
Topics: Animals; Bee Venoms; Female; Glycogen; Ibuprofen; Indomethacin; Intercellular Signaling Peptides and Proteins; Kinetics; Liver; Melitten; Peptides; Prostaglandin D2; Rats; Rats, Inbred Strains; Thromboxane B2; Vasoconstriction; Wasp Venoms | 1990 |
Stimulation of release of prostaglandin D2 and thromboxane B2 from perfused rat liver by extracellular adenosine.
Topics: Acetophenones; Adenosine; Animals; Blood Pressure; Glucose; Ibuprofen; Indomethacin; Liver; Male; Portal System; Prostaglandin D2; Rats; Rats, Inbred Strains; Secretory Rate; Sulfonamides; Thromboxane B2 | 1990 |
The cyclo-oxygenase inhibitors indomethacin and ibuprofen inhibit the insulin-induced stimulation of ribosomal RNA synthesis in L6 myoblasts.
Topics: Animals; Ibuprofen; In Vitro Techniques; Indomethacin; Insulin; Insulin Antagonists; L Cells; Mice; Muscles; Ribosomes; RNA; RNA, Ribosomal | 1989 |
Differential effects of ibuprofen, indomethacin, and meclofenamate on prostaglandin endoperoxide H2 metabolism.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cats; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Ibuprofen; In Vitro Techniques; Indomethacin; Intramolecular Oxidoreductases; Isomerases; Lung; Meclofenamic Acid; Microsomes; ortho-Aminobenzoates; Prostaglandin Antagonists; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandin-E Synthases; Prostaglandins H; Thromboxane-A Synthase | 1989 |
Coronary constriction due to neuropeptide Y: alleviation with cyclooxygenase blockers.
Topics: Animals; Coronary Vessels; Cyclooxygenase Inhibitors; Dogs; Ibuprofen; Indomethacin; Myocardium; Neuropeptide Y; Oxygen Consumption; Vasoconstriction | 1989 |
Interleukin 1-induced prostaglandin E2 accumulation by isolated pancreatic islets.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; Glucose; Glycolysis; Ibuprofen; In Vitro Techniques; Indomethacin; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Kinetics; Male; Rats; Rats, Inbred Strains; Recombinant Proteins | 1989 |
Regulation of murine hematopoiesis by arachidonic acid metabolites.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonic Acids; B-Lymphocytes; Cyclooxygenase Inhibitors; Granulocytes; Hematopoiesis; Hematopoietic Stem Cells; Hydroxyeicosatetraenoic Acids; Ibuprofen; In Vitro Techniques; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Mice; Prostaglandins; Thromboxane B2; Umbelliferones | 1989 |
Role of plasminogen activators and leukocytes in IUD-induced inflammation: effect of some anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Endometritis; Epithelium; Female; Ibuprofen; Indomethacin; Intrauterine Devices; Leukocyte Count; Naproxen; Neutrophils; Organ Size; ortho-Aminobenzoates; Plasminogen Activators; Rats; Uterus | 1989 |
Evaluation of post-cardiopulmonary bypass Sonoclot signatures in patients taking nonsteroidal anti-inflammatory drugs.
Topics: Aspirin; Blood Loss, Surgical; Blood Platelets; Blood Viscosity; Cardiopulmonary Bypass; Evaluation Studies as Topic; Fibrinogen; Humans; Ibuprofen; Indomethacin; Partial Thromboplastin Time; Platelet Count; Protamines; Prothrombin Time; Whole Blood Coagulation Time | 1989 |
Defective modulation of noradrenergic neurotransmission by endogenous prostaglandins in aging spontaneously hypertensive rats.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Ibuprofen; Indomethacin; Male; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Reference Values; Sympathetic Nervous System; Synaptic Transmission | 1989 |
Central interleukin 1-elicited hyperinsulinemia is mediated by prostaglandins but not autonomics.
Topics: Acetophenones; Adrenocorticotropic Hormone; Animals; Atropine; Autonomic Nervous System; Body Temperature; Cerebral Ventricles; Dinoprostone; Glucagon; Hexamethonium; Hexamethonium Compounds; Hyperinsulinism; Ibuprofen; Indomethacin; Injections, Intraventricular; Insulin; Insulin Secretion; Interleukin-1; Male; Meclofenamic Acid; Phentolamine; Propranolol; Propyl Gallate; Rats; Reference Values; SRS-A; Tetrazoles; Vagotomy | 1989 |
Active substance from the serum of laying hens and its effect on uterine smooth muscles.
Topics: Animals; Chickens; Chromatography, Gel; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Female; Ibuprofen; In Vitro Techniques; Indomethacin; Molecular Weight; Muscle, Smooth; Oxytocin; Prostaglandins F; Ultrafiltration; Uterine Contraction | 1989 |
The effect of indomethacin, aspirin, and ibuprofen on bone ingrowth into a porous-coated implant.
Topics: Animals; Aspirin; Bone and Bones; Chromium Alloys; Dose-Response Relationship, Drug; Femur; Ibuprofen; Indomethacin; Injections, Subcutaneous; Prostheses and Implants; Rabbits; Surface Properties; Time Factors | 1989 |
Comparative acute effects of aspirin, diflunisal, ibuprofen and indomethacin on renal function in healthy man.
Topics: Adult; Aspirin; Diflunisal; Humans; Ibuprofen; Indomethacin; Kidney; Kidney Function Tests; Male | 1989 |
Synthesis and pharmacological evaluation of conjugates of prednisolone and non-steroidal anti-inflammatory agents.
Topics: Adrenal Glands; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry; Corticosterone; Drug Combinations; Drug Evaluation, Preclinical; Granuloma; Ibuprofen; Indomethacin; Male; Prednisolone; Rats; Rats, Inbred Strains; Thymus Gland | 1989 |
Study on the in vitro assay method for evaluating the inhibitory effect of various substances on the production of plasma kallikrein.
Topics: Aminopyrine; Aspirin; Humans; Ibuprofen; Indomethacin; Kallikreins; Ketoprofen; Kinetics; Kinins; Morphine; Pentazocine; Prekallikrein | 1989 |
[Pharmacological study of kako-bushi-matsu: analgesic action and acute toxicity].
Topics: Analgesics; Animals; Aspirin; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Ibuprofen; Indomethacin; Lethal Dose 50; Male; Mice; Rats; Rats, Inbred Strains | 1989 |
Effects of aspirin-like drugs on Walker 256 tumor growth and cachexia in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Weight; Cachexia; Carcinoma 256, Walker; Cell Division; Ibuprofen; Indomethacin; Male; Neoplasm Transplantation; Prostaglandin Antagonists; Prostaglandins E; Rats | 1989 |
A new writhing model of factor XII activator-induced pain for assessment of non-steroidal anti-inflammatory agents. I. Kaolin-induced writhing in mice.
Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Captopril; Drug Synergism; Glycine max; Ibuprofen; Indomethacin; Kaolin; Kinetics; Male; Mice; Mice, Inbred ICR; Pain; Pain Measurement; Propionates; Trypsin Inhibitors | 1989 |
Determinants of sensitization of carotid baroreceptors by pulsatile pressure in dogs.
Topics: Animals; Carotid Arteries; Carotid Sinus; Dogs; Endothelium, Vascular; Ibuprofen; In Vitro Techniques; Indomethacin; Pressoreceptors; Pressure; Time Factors | 1989 |
Indomethacin increases the formation of lipoxygenase products in calcium ionophore stimulated human neutrophils.
Topics: Aspirin; Calcimycin; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; In Vitro Techniques; Indomethacin; Kinetics; Leukotriene B4; Lipoxygenase; Neutrophils; SRS-A | 1987 |
Effects of isoxicam and other non-steroidal anti-inflammatory drugs on arachidonic acid metabolism by rat peritoneal leucocytes.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Calcimycin; Hydroxyeicosatetraenoic Acids; Ibuprofen; In Vitro Techniques; Indomethacin; Leukocytes; Male; Naproxen; Piroxicam; Prostaglandins; Rats; Rats, Inbred Strains; Thiazines | 1985 |
Non-steroidal anti-inflammatory drugs and bleeding peptic ulcer.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Duodenal Ulcer; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Osteoarthritis; Peptic Ulcer Hemorrhage; Piroxicam; Smoking; Stomach Ulcer; Surveys and Questionnaires; Thiazines | 1986 |
The role of pharmacologic agents in the prevention or treatment of allergic food disorders.
Topics: Administration, Oral; Adult; Aspirin; Beclomethasone; Child; Cromolyn Sodium; Dermatitis, Atopic; Food Hypersensitivity; Histamine H1 Antagonists; Humans; Ibuprofen; Indomethacin; Infant; Ketotifen; Nifedipine | 1986 |
Analgesic and anti-inflammatory activities in rats of alpha-(3,5-di-t-butyl-4-hydroxybenzylidene)-gamma-butyrolactone (KME-4), and its intestinal damage.
Topics: 4-Butyrolactone; Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Capillary Permeability; Edema; Furans; Ibuprofen; Indomethacin; Intestinal Diseases; Lethal Dose 50; Male; Naproxen; Rats; Rats, Inbred Strains | 1986 |
The effect of vasoactive agents on the contractions of the initial lymphatics of the bat's wing.
Topics: Animals; Bradykinin; Chiroptera; Dinoprost; Histamine; Ibuprofen; Indomethacin; Lymphatic System; Neurotransmitter Agents; Prostaglandins F; Vasoconstrictor Agents; Vasodilator Agents; Wings, Animal | 1987 |
Effect of ibuprofen and indomethacin on human plasma melatonin.
Topics: Adult; Delayed-Action Preparations; Humans; Ibuprofen; Indomethacin; Male; Melatonin | 1987 |
[Drug therapy of dysmenorrhea].
Topics: Adrenergic beta-Agonists; Adult; Aspirin; Calcium Channel Blockers; Contraceptives, Oral; Dysmenorrhea; Female; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Magnesium; Mefenamic Acid; Models, Biological; Naproxen; Progestins | 1988 |
A macrophage defect in women with recurrent Candida vaginitis and its reversal in vitro by prostaglandin inhibitors.
Topics: Candidiasis, Vulvovaginal; Cell Adhesion; Female; Humans; Ibuprofen; Indomethacin; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Macrophages; Masoprocol; Mitogens; Prostaglandin Antagonists; Recurrence | 1986 |
Inhibition of prostaglandin biosynthesis by etodolac. I. Selective activities in arthritis.
Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cartilage; Cattle; Cells, Cultured; Dinoprostone; Etodolac; Female; Ibuprofen; Indomethacin; Macrophages; Male; Mice; Mice, Inbred C57BL; Piroxicam; Prostaglandin Antagonists; Prostaglandins; Prostaglandins E; Rats; Rats, Inbred Strains; Synovial Fluid | 1987 |
Human gamma interferon induction by staphylococcal protein A: effector cells, kinetics and the effect of prostaglandin, indomethacin, ibuprofen and aspirin.
Topics: Aspirin; Dinoprostone; Humans; Ibuprofen; In Vitro Techniques; Indomethacin; Interferon-gamma; Kinetics; Monocytes; Prostaglandins E; Prostaglandins E, Synthetic; Staphylococcal Protein A; T-Lymphocytes; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory | 1988 |
Identification of hydrogen peroxide and hydroxyl radicals as mediators of leukocyte-induced myocardial dysfunction. Limitation of infarct size with neutrophil inhibition and depletion.
Topics: Adenosine Triphosphatases; Animals; Butylated Hydroxytoluene; Calcium; Catalase; Dogs; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Ibuprofen; Indomethacin; Leukocytes; Male; Mannitol; Myocardial Infarction; Myocardium; Neutrophils; Sarcoplasmic Reticulum; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1985 |
Evidence that the beta-adrenergic system and prostaglandins stimulate renin release through different mechanisms.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Female; Humans; Ibuprofen; Indomethacin; Infusions, Parenteral; Isoproterenol; Male; Middle Aged; Propranolol; Prostaglandins; Receptors, Adrenergic, beta; Renin | 1985 |
Prostanoid modulation (mediation?) of certain behavioral effects of ethanol.
Topics: Alcoholism; Alprostadil; Animals; Aspirin; Brain; Ethanol; Fatty Acids; Fatty Acids, Essential; Fatty Acids, Unsaturated; gamma-Linolenic Acid; Humans; Ibuprofen; Indomethacin; Linoleic Acids; Linolenic Acids; Male; Mice; Oenothera biennis; Plant Oils; Prostaglandins; Prostaglandins E; Prostanoic Acids; Substance Withdrawal Syndrome | 1985 |
Mechanism of bradykinin, ADH, and cAMP interaction in rabbit cortical collecting duct.
Topics: Adenylate Cyclase Toxin; Animals; Biomechanical Phenomena; Bradykinin; Cyclic AMP; Drug Interactions; Electrophysiology; Female; Ibuprofen; Indomethacin; Kidney Tubules; Kidney Tubules, Collecting; Pertussis Toxin; Rabbits; Sodium; Vasopressins; Virulence Factors, Bordetella; Water | 1985 |
Role of prostaglandins in controlling plasma fibronectin levels.
Topics: Animals; Epoprostenol; Fibronectins; Ibuprofen; Imidazoles; Indomethacin; Prostaglandins; Rats; Rats, Inbred Strains; Thromboxane A2 | 1988 |
Suppression of inflammatory oedema by ibuprofen involving a mechanism independent of cyclo-oxygenase inhibition.
Topics: Animals; Capillary Permeability; Cyclooxygenase Inhibitors; Edema; Ibuprofen; Imidazoles; Indomethacin; Inflammation; Injections, Intradermal; Male; Prostaglandins; Rabbits; Skin; Thromboxane-A Synthase; Vasodilation | 1986 |
The history of diclofenac.
Topics: Chemical Phenomena; Chemistry; Diclofenac; Humans; Hydrogen-Ion Concentration; Ibuprofen; Indenes; Indomethacin; Ketoprofen; Naproxen; Phenylbutazone; Piroxicam; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship; Thiazines | 1986 |
Contribution of prostaglandins to reperfusion-induced ventricular failure in isolated rat hearts.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Coronary Circulation; Coronary Disease; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Epoprostenol; Ibuprofen; Indomethacin; Male; Myocardial Contraction; Myocardium; Perfusion; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains | 1986 |
Antitumor activity in a rat mammary adenocarcinoma: the effect of cyclooxygenase inhibitors and immunization against prostaglandin E2.
Topics: Animals; Antineoplastic Agents; Cyclooxygenase Inhibitors; Dinoprostone; Female; Flurbiprofen; Ibuprofen; Immunization; Indomethacin; Mammary Neoplasms, Experimental; Prostaglandins E; Rats; Rats, Inbred F344 | 1986 |
Effect of cyclooxygenase inhibition on ethchlorvynol-induced acute lung injury in dogs.
Topics: Animals; Body Water; Cyclooxygenase Inhibitors; Disease Models, Animal; Dogs; Ethchlorvynol; Hypoxia; Ibuprofen; Indomethacin; Lung; Lung Injury; Male; Oxygen; Pulmonary Circulation; Pulmonary Edema | 1986 |
Eicosanoid regulation of oosporogenesis by Lagenidium giganteum.
Topics: Apicomplexa; Chytridiomycota; Cyclooxygenase Inhibitors; Fatty Acids; Ibuprofen; Indomethacin; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; Oomycetes; Parasites; Prostaglandin-Endoperoxide Synthases; Reproduction; Salicylamides; Spores, Fungal | 1986 |
Effects of phorbol esters on sodium and chloride transport in rat colon.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Biological Transport; Calcium; Chlorides; Colon; Ibuprofen; Indomethacin; Intestinal Absorption; Phorbol 12,13-Dibutyrate; Phorbol Esters; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Rats; Rats, Inbred Strains; Sodium; Tetrodotoxin; Verapamil | 1986 |
Prostaglandin involvement in the evoked release of D-aspartate from cerebellar mossy fiber terminals.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspartic Acid; Biological Transport; Cerebellum; Dinoprost; Dinoprostone; Ibuprofen; Indomethacin; Kinetics; Potassium; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Stereoisomerism; Tetrodotoxin; Verapamil | 1986 |
The functional significance of the regulation of macrophage Ia expression by endogenous arachidonate metabolites in vitro.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; Female; Histocompatibility Antigens Class II; Ibuprofen; Indomethacin; Macrophage Activation; Macrophages; Mice; Mice, Inbred Strains; Prostaglandins E; SRS-A; Thromboxanes | 1986 |
Tumor necrosis factor-alpha (cachectin) stimulates bone resorption in mouse calvaria via a prostaglandin-mediated mechanism.
Topics: Animals; Aspirin; Bone and Bones; Bone Resorption; Calcium; Cyclooxygenase Inhibitors; Dinoprostone; Glycoproteins; Ibuprofen; Indomethacin; Mice; Organ Culture Techniques; Piroxicam; Prostaglandins E; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1987 |
The toxic effects of tumor necrosis factor in vivo and their prevention by cyclooxygenase inhibitors.
Topics: Animals; Antineoplastic Agents; Body Temperature; Cyclooxygenase Inhibitors; Cytotoxins; Endotoxins; Glycoproteins; Ibuprofen; Indomethacin; Male; Rats; Tumor Necrosis Factor-alpha | 1987 |
Cyclooxygenase inhibition reduces placental transfer: reversal by carbacyclin.
Topics: Antipyrine; Cyclooxygenase Inhibitors; Epoprostenol; Female; Humans; Ibuprofen; Indomethacin; Maternal-Fetal Exchange; Placenta; Pregnancy | 1987 |
Specific inhibition of phorbol diester-induced granulocyte-macrophage progenitor cell (GM-CFU) differentiation by lipoxygenase inhibitors.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Ascorbic Acid; Butylated Hydroxyanisole; Cell Differentiation; Colony-Forming Units Assay; Dexamethasone; Granulocytes; Hematopoietic Stem Cells; Ibuprofen; Indomethacin; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Mice; Tetradecanoylphorbol Acetate | 1987 |
Role of prostaglandins in blood-induced vasoconstriction of canine cerebral arteries.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood; Cerebral Arteries; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Dogs; Female; Ibuprofen; Indomethacin; Male; Meclofenamic Acid; Papaverine; Prostaglandins; Prostaglandins E; Prostaglandins F; Vasoconstriction | 1988 |
Further studies on the effects of cyclooxygenase inhibitors on compensatory renal growth.
Topics: Animals; Cyclooxygenase Inhibitors; DNA; Ibuprofen; Indomethacin; Kidney; Male; Meclofenamic Acid; Nephrectomy; Organ Size; ortho-Aminobenzoates; Rats; Rats, Inbred Strains | 1987 |
Molecular mechanisms of acidic amino acid release from mossy fiber terminals of rat cerebellum.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspartic Acid; Biological Transport; Cerebellar Cortex; Fatty Acids, Nonesterified; Ibuprofen; Indomethacin; Kinetics; Male; Potassium; Rats | 1987 |
Effects of five non-steroidal anti-inflammatory drugs on the renal and systemic responses to arachidonate in conscious dogs.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Aspirin; Dinoprostone; Dogs; Ibuprofen; Indomethacin; Kidney; Kidney Cortex; Microsomes; Phenylbutazone; Prostaglandins; Prostaglandins E; Sulindac | 1987 |
Prostaglandin synthesis by squamous carcinoma cells of head and neck, and its inhibition by non-steroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Carcinoma, Squamous Cell; Cell Line; Dinoprostone; Facial Neoplasms; Humans; Ibuprofen; Indomethacin; Prostaglandin Antagonists; Prostaglandins; Prostaglandins E; Tongue Neoplasms | 1987 |
Nonsteroidal anti-inflammatory drugs correct the bactericidal defect of polymorphonuclear leukocytes in a guinea pig model of thermal injury.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Bactericidal Activity; Blood Cell Count; Burns; Complement System Proteins; Concanavalin A; Cyclooxygenase Inhibitors; Disease Models, Animal; Guinea Pigs; Ibuprofen; Indomethacin; Kinetics; Lymphocyte Activation; Neutrophils; Phagocytosis; Piroxicam; Pseudomonas aeruginosa; Spleen; Thromboxane B2 | 1988 |
A monoclonal anti-thromboxane B2 antibody.
Topics: Animals; Antibodies, Monoclonal; Antibody Affinity; Antibody Specificity; Arachidonic Acid; Arachidonic Acids; Humans; Ibuprofen; Imidazoles; Immunoglobulin G; Indomethacin; Mice; Mice, Inbred BALB C; Platelet Aggregation; Radioimmunoassay; Thromboxane A2; Thromboxane B2 | 1988 |
Prevention of heterotopic ossification by nonsteroid antiinflammatory drugs after total hip arthroplasty.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Hip Joint; Hip Prosthesis; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Ossification, Heterotopic; Postoperative Complications; Radiography | 1988 |
Prevention of periarticular heterotopic ossification following total hip arthroplasty. Clinical experience with indomethacin and ibuprofen.
Topics: Aged; Aged, 80 and over; Female; Hip Prosthesis; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Ossification, Heterotopic | 1988 |
Effect of hypoxia on bronchial circulation.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Bronchi; Bronchial Arteries; Hypoxia; Ibuprofen; Indomethacin; Male; Prostaglandins; Sheep; Vascular Resistance; Vasodilation | 1988 |
Improving micrograft patency.
Topics: Animals; Aspirin; Blood Vessel Prosthesis; Carotid Artery, Internal; Female; Humans; Ibuprofen; Indomethacin; Jugular Veins; Microsurgery; Platelet Aggregation Inhibitors; Polytetrafluoroethylene; Rats; Rats, Inbred Strains; Umbilical Veins; Vascular Patency | 1988 |
Thermodynamic study on enhancement of percutaneous penetration of drugs by Azone.
Topics: Administration, Cutaneous; Animals; Azepines; Drug Synergism; Ethanol; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Rats; Rats, Inbred Strains; Solubility; Solvents; Sulfanilamides; Thermodynamics | 1988 |
Inhibition by anti-inflammatory agents of contraction induced by epidermal growth factor-urogastrone in isolated longitudinal smooth muscle strips from guinea-pig stomach.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Auranofin; Cycloheximide; Dexamethasone; Epidermal Growth Factor; Guinea Pigs; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Naproxen; Steroids; Stomach | 1988 |
[Inhibitory effect of AD-1590, a non-steroidal anti-inflammatory drug, on allergic inflammation in mice and rats].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experimental; Dermatitis, Contact; Dibenzoxepins; Ibuprofen; Indomethacin; Male; Mice; Passive Cutaneous Anaphylaxis; Rats; Rats, Inbred Strains | 1988 |
Increased hemodynamic and survival with endotoxin and septic shock with ibuprofen treatment.
Topics: Animals; Anti-Bacterial Agents; Escherichia coli Infections; Hemodynamics; Ibuprofen; Indomethacin; Sheep; Shock, Septic | 1987 |
Differential in vivo effects of indomethacin, ibuprofen, and flurbiprofen on oxygen-dependent killing activities of neutrophils elicited by acute nonimmune inflammation in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Flurbiprofen; Ibuprofen; Indomethacin; Inflammation; Male; Neutrophils; Oxygen; Phagocytosis; Rats; Rats, Inbred Strains | 1988 |
The effect of indomethacin, ibuprofen and paracetamol on the TRH induced TSH secretion in the rat.
Topics: Acetaminophen; Animals; Hypothalamus; Ibuprofen; Indomethacin; Male; Pituitary Gland; Rats; Thyrotropin | 1988 |
Analgesic activity following combined oral administration of flupirtine maleate and peripherally acting analgesics in mice and rats.
Topics: Acetaminophen; Administration, Oral; Aminopyridines; Analgesics; Animals; Aspirin; Drug Evaluation, Preclinical; Drug Synergism; Ibuprofen; Indomethacin; Male; Mice; Mice, Inbred Strains; Pain Measurement; Peripheral Nerves; Rats; Rats, Inbred Strains | 1987 |
Inhibition of trans-dihydrodiol oxidation by the non-steroidal anti-inflammatory drugs.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Anti-Inflammatory Agents; Aspirin; Benzopyrenes; Dihydroxydihydrobenzopyrenes; Flufenamic Acid; Ibuprofen; Indomethacin; Liver; Male; Meclofenamic Acid; Mefenamic Acid; Oxidoreductases; Rats; Sulindac; Tolmetin | 1986 |
Modulation of tumor cell motility by prostaglandins and inhibitors of prostaglandin synthesis.
Topics: Animals; Arbaprostil; Cell Line; Cell Movement; Dinoprostone; Fibrosarcoma; Ibuprofen; Indomethacin; Mice; Prostaglandin Antagonists; Prostaglandins; Prostaglandins E; SRS-A | 1986 |
Effect of non-steroidal anti-inflammatory drugs and prostaglandins on the permeability of the human small intestine.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dinoprostone; Humans; Ibuprofen; Indomethacin; Intestine, Small; Permeability; Prostaglandins E; Ranitidine | 1986 |
[The analgesic and antipyretic effects of a non-steroidal antiinflammatory agent, EB-382, in experimental animals].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Ibuprofen; Indomethacin; Mice; Morphine; Pain; Phenylbutazone; Propionates; Rats; Rats, Inbred Strains | 1986 |
Piroxicam and gastrointestinal bleeding.
Topics: Adult; Aged; Aged, 80 and over; Aspirin; Drug Utilization; Female; Gastrointestinal Hemorrhage; Hospitalization; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Norway; Piroxicam; Prospective Studies | 1986 |
Comparative studies on the gastrointestinal lesions caused by several nonsteroidal anti-inflammatory agents in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Feces; Gastric Mucosa; Gastrointestinal Hemorrhage; Ibuprofen; Indomethacin; Intestinal Mucosa; Oxaprozin; Phenylpropionates; Propionates; Rats | 1987 |
Evidence that prostacyclin modulates the vascular actions of calcium in man.
Topics: 6-Ketoprostaglandin F1 alpha; Blood Pressure; Calcium; Creatinine; Dinoprostone; Drug Interactions; Epoprostenol; Hemodynamics; Humans; Ibuprofen; Indomethacin; Kidney; Natriuresis; Nifedipine; Potassium; Prazosin; Prostaglandins E; Regional Blood Flow; Sulindac; Vascular Resistance; Vasodilation | 1986 |
Ibuprofen prevents synthetic smoke-induced pulmonary edema.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Drug Evaluation, Preclinical; Epoprostenol; Germ-Free Life; Hemodynamics; Hydrochloric Acid; Ibuprofen; Indomethacin; Lung; Male; Pulmonary Edema; Rats; Rats, Inbred Strains; Smoke; Thromboxane B2 | 1986 |
Cytoprotective agents in experimental small bowel volvulus.
Topics: Alprostadil; Animals; Aspirin; Ephedrine; Ibuprofen; Indomethacin; Intestinal Obstruction; Intestine, Small; Rats; Rats, Inbred Strains; Superoxide Dismutase | 1987 |
Indomethacin and ibuprofen-induced reversible acute renal failure in a patient with systemic lupus erythematosus.
Topics: Acute Kidney Injury; Female; Humans; Hydrochlorothiazide; Ibuprofen; Indomethacin; Lupus Nephritis; Middle Aged; Triamterene | 1987 |
The effect of steroidal and nonsteroidal anti-inflammatory agents on granulocyte migration into bovine pulmonary artery intimal explants.
Topics: Animals; Anti-Inflammatory Agents; Cattle; Cell Adhesion; Cell Movement; Dose-Response Relationship, Drug; Granulocytes; Ibuprofen; Indomethacin; Methylprednisolone; Pulmonary Artery | 1986 |
Exaggerated hypotension by N-formylmethionylleucyl-phenylalanine in indomethacin pretreated rats. Role of toxic oxygen.
Topics: Animals; Ascorbic Acid; Blood Pressure; Dimethyl Sulfoxide; Endotoxins; Female; Glucagon; Hypotension; Ibuprofen; Indomethacin; Isoproterenol; N-Formylmethionine Leucyl-Phenylalanine; Oxygen; Rats; Rats, Inbred Strains; Theophylline | 1986 |
Indomethacin and ibuprofen enhance anoxia-induced hyperemia in rat brain.
Topics: Animals; Blood Pressure; Cerebrovascular Circulation; Diclofenac; Extracorporeal Circulation; Hyperemia; Hypoxia, Brain; Ibuprofen; Indomethacin; Male; Rats; Rats, Inbred Strains | 1986 |
Effects of steroids and nonsteroid anti-inflammatory agents on vascular permeability in a rat glioma model.
Topics: Animals; Anti-Inflammatory Agents; Blood-Brain Barrier; Brain Edema; Brain Neoplasms; Capillary Permeability; Cell Line; Dexamethasone; Glioma; Ibuprofen; Indomethacin; Methylprednisolone; Neoplasms, Experimental; Rats; Rats, Inbred Strains | 1986 |
A novel biologically active seleno-organic compound--VI. Protection by ebselen (PZ 51) against galactosamine/endotoxin-induced hepatitis in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Azoles; Chemical and Drug Induced Liver Injury; Dexamethasone; Diethylcarbamazine; Endotoxins; Galactosamine; Glutathione; Glutathione Disulfide; Hepatitis, Animal; Ibuprofen; Indomethacin; Isoindoles; L-Iditol 2-Dehydrogenase; Male; Mice; Organoselenium Compounds; Selenium; Time Factors | 1986 |
Pharmacological studies of antigen-induced arthritis in BALB/c mice. I. Characterization of the arthritis and the effects of steroidal and non-steroidal anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Dexamethasone; Female; Flurbiprofen; Ibuprofen; Indomethacin; Joints; Leukocyte Count; Lymphocytes; Mice; Mice, Inbred BALB C; Monocytes; Neutrophils; Prednisolone; Time Factors | 1986 |
An automated microcomputer-based system for determining canine paw pressure quantitatively in the dog synovitis model.
Topics: Animals; Anti-Inflammatory Agents; Disease Models, Animal; Dogs; Female; Foot; Ibuprofen; Indomethacin; Male; Microcomputers; Pressure; Software; Synovitis; Time Factors | 1986 |
Effect of dexamethasone, indomethacin, ibuprofen, and probenecid on carrageenan-induced brain inflammation.
Topics: Animals; Anti-Inflammatory Agents; Brain Edema; Capillary Permeability; Carrageenan; Cerebrovascular Circulation; Dexamethasone; Encephalitis; Hindlimb; Ibuprofen; Indomethacin; Male; Mice; Mice, Inbred Strains; Probenecid | 1986 |
[Gastric potential difference: effects of non-steroidal anti-inflammatory agents in the healthy volunteer].
Topics: Action Potentials; Adolescent; Adult; Anti-Inflammatory Agents; Female; Gastric Mucosa; Humans; Ibuprofen; Indomethacin; Male; Phenylbutazone; Phenylpropionates | 1985 |
Ibuprofen, methylprednisolone, and gentamicin as conjoint therapy in septic shock.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Disease Models, Animal; Drug Therapy, Combination; Female; Gentamicins; Ibuprofen; Indomethacin; Methylprednisolone; Peritonitis; Rats; Shock, Septic; Thromboxane B2 | 1985 |
NSAID-plasma concentration monitoring--optimizing treatment of R.A.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Humans; Ibuprofen; Indomethacin; Kinetics; Metabolic Clearance Rate; Naproxen; Phenylacetates; Phenylbutazone | 1985 |
[Effect of pirprofen on bradykinin-induced flexor reflexes of rat and rabbit hindlimbs].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Hindlimb; Ibuprofen; Indomethacin; Male; Phenylpropionates; Rabbits; Rats; Reflex; Species Specificity | 1985 |
[The modes of anti-inflammatory and analgesic actions of 2-[4-(3-methyl-2-butenyl) phenyl] propionic acid (TA-60) and 2-[4-(2,2-dichlorovinyl) phenyl] propionic acid (TA-668) and effect of TA-60 on the gastrointestinal tract].
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Benzothiazoles; Diarrhea; Epirizole; Guinea Pigs; Ibuprofen; Indomethacin; Intestinal Mucosa; Male; Necrosis; Phenylpropionates; Piperazines; Rats; Stomach Diseases | 1985 |
Coronary flow regulation in patients with ischemic heart disease: release of purines and prostacyclin and the effect of inhibitors of prostaglandin formation.
Topics: Adenosine; Adult; Aged; Coronary Circulation; Coronary Disease; Epoprostenol; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Prostaglandins; Purines; Vascular Resistance | 1985 |
Interaction between non-steroidal antiinflammatory agents and sodium salicylate in the relaxant response of dog renal arteries to angiotensin II.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Dogs; Epoprostenol; Female; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Meclofenamic Acid; Muscle Relaxation; Muscle, Smooth, Vascular; Renal Artery; Sodium Salicylate | 1985 |
Morphological alterations in cultured endothelial cells induced by arachidonic acid.
Topics: Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Aspirin; Cattle; Dinoprostone; Dose-Response Relationship, Drug; Endothelium; Fatty Acids; Female; Ibuprofen; Indomethacin; Kinetics; Male; Phospholipids; Prostaglandins E; Pulmonary Artery; SRS-A; Time Factors | 1985 |
Effect of inhibitors of proteolysis and arachidonic acid metabolism on burn-induced protein breakdown.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Burns; Hindlimb; Ibuprofen; In Vitro Techniques; Indomethacin; Leupeptins; Lysosomes; Muscles; Oligopeptides; Peptide Hydrolases; Protease Inhibitors; Proteins; Quinacrine; Rats; Rats, Inbred Strains; Tyrosine | 1985 |
Prostaglandin involvement in hypersensitivity of ischemic hearts to arrhythmogenic influence of ouabain.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Arrhythmias, Cardiac; Aspirin; Coronary Circulation; Coronary Disease; Coronary Vessels; Dinoprost; Dinoprostone; Epoprostenol; Guinea Pigs; Ibuprofen; Indomethacin; Ligation; Male; Ouabain; Perfusion; Prostaglandins; Prostaglandins E; Prostaglandins F; Time Factors | 1985 |
Pulmonary transvascular fluid and protein exchange after thrombin-induced microembolism. Differential effects of cyclooxygenase inhibitors.
Topics: Animals; Blood Proteins; Capillary Permeability; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Epoprostenol; Extracellular Space; Hemodynamics; Ibuprofen; Indomethacin; Lung; Lymph; Meclofenamic Acid; Pulmonary Embolism; Sheep; Thrombin; Thromboxane B2; Vascular Resistance | 1985 |
Differential effects of prostaglandin synthetase inhibitors on EEG in rat.
Topics: Acetaminophen; Animals; Cyclooxygenase Inhibitors; Electroencephalography; Female; Ibuprofen; Indomethacin; Meclofenamic Acid; Mefenamic Acid; Motor Activity; Rats; Rats, Inbred Strains | 1985 |
Stimulation of ovine placental lactogen secretion by arachidonic acid.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Female; Fetal Blood; Gestational Age; Ibuprofen; Indomethacin; Placenta; Placental Lactogen; Pregnancy; Progesterone; Sheep; Stimulation, Chemical | 1985 |
Differential effect of prostaglandin synthetase inhibitor pretreatment on pentylenetetrazol-induced seizures in rat.
Topics: Acetaminophen; Animals; Behavior, Animal; Cyclooxygenase Inhibitors; Electric Stimulation; Electroencephalography; Female; Hydrogen-Ion Concentration; Ibuprofen; Indomethacin; Meclofenamic Acid; Mefenamic Acid; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures | 1985 |
The pulmonary hypertension of sclerosing agents is prevented by cyclooxygenase inhibitors.
Topics: Animals; Blood Pressure; Cyclooxygenase Inhibitors; Drug Combinations; Female; Hypertension, Pulmonary; Ibuprofen; Indomethacin; Lung; Lymph; Lymphatic Diseases; Organ Size; Pulmonary Wedge Pressure; Sclerosing Solutions; Serum Albumin; Sheep; Sodium Morrhuate; Sodium Tetradecyl Sulfate | 1985 |
Increased production of lipoxygenase products by cholesterol-rich mouse macrophages.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonic Acids; Arteriosclerosis; Cells, Cultured; Cholesterol; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indomethacin; Lipoxygenase; Macrophages; Male; Mice | 1985 |
The effects of diclofenac sodium on arachidonic acid metabolism.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Chemotaxis, Leukocyte; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indomethacin; Leukocytes; Lipoxygenase; Naproxen; Phospholipases A; Phospholipases A2; Phospholipids; Piroxicam; Prostaglandins E; SRS-A; Thiazines; Triglycerides | 1985 |
In vivo modulation of leukotaxis by non-steroidal anti-inflammatory drugs.
Topics: Animals; Anterior Chamber; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Chemotaxis, Leukocyte; Female; Flurbiprofen; Ibuprofen; Indomethacin; N-Formylmethionine Leucyl-Phenylalanine; Rabbits | 1985 |
Antitumor activity in a rat mammary adenocarcinoma: the effect of cyclooxygenase inhibitors and immunization against prostaglandin E2.
Topics: Adenocarcinoma; Animals; Antibodies; Antineoplastic Agents; Cell Line; Cyclooxygenase Inhibitors; Dinoprostone; Female; Flurbiprofen; Ibuprofen; Immunotherapy; Indomethacin; Mammary Neoplasms, Experimental; Propionates; Prostaglandins E; Rats; Rats, Inbred F344 | 1985 |
Comparative effects of four prostaglandin synthesis inhibitors on the obstructed kidney in the dog.
Topics: Animals; Blood Pressure; Dogs; Female; Ibuprofen; Indomethacin; Ketorolac; Kidney Pelvis; Naproxen; Pressure; Prostaglandin Antagonists; Tolmetin; Ureteral Obstruction | 1986 |
European experience with flurbiprofen. A new analgesic/anti-inflammatory agent.
Topics: Aspirin; Drug Evaluation; Europe; Flurbiprofen; Humans; Ibuprofen; Indomethacin; Naproxen; Propionates | 1986 |
Role of prostaglandins in the renal handling of a salt load in essential hypertension.
Topics: Adolescent; Adult; Blood Pressure; Cardiac Output; Diuresis; Female; Humans; Hypertension; Ibuprofen; Indomethacin; Kidney; Male; Middle Aged; Potassium; Prostaglandins; Sodium; Sodium Chloride; Sulindac; Vascular Resistance | 1985 |
Arachidonic acid metabolites stimulate phosphatidylcholine secretion in primary cultures of type II pneumocytes.
Topics: Animals; Arachidonic Acids; Catechols; Cells, Cultured; Dose-Response Relationship, Drug; Flufenamic Acid; Ibuprofen; In Vitro Techniques; Indomethacin; Lung; Male; Masoprocol; Naproxen; Phosphatidylcholines; Rats; Rats, Inbred Strains | 1985 |
Nephrotoxicity from nonsteroidal anti-inflammatory drugs.
Topics: Acute Disease; Acute Kidney Injury; Aged; Anti-Inflammatory Agents; Aspirin; Female; Humans; Hyperkalemia; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Nephritis, Interstitial | 1985 |
Effects of some anti-inflammatory drugs on 12 blood constituents: protocol for the study of in vivo effects of drugs.
Topics: Anti-Inflammatory Agents; Aspirin; Blood Chemical Analysis; Blood Urea Nitrogen; Cholesterol; Creatinine; Diclofenac; Humans; Ibuprofen; Indomethacin; Iron; Ketoprofen; Prospective Studies; Retrospective Studies; Serum Albumin; Time Factors; Triglycerides; Uric Acid | 1985 |
Effect of ibuprofen and indomethacin on the O2 supply/consumption balance in ischemic rabbit myocardium.
Topics: Animals; Anti-Inflammatory Agents; Coronary Circulation; Coronary Disease; Heart; Ibuprofen; Indomethacin; Inflammation; Myocardium; Oxygen Consumption; Rabbits | 1985 |
Nonsteroidal anti-inflammatory agents. A review of the literature.
Topics: Absorption; Anti-Inflammatory Agents; Aspirin; Diflunisal; Drug Interactions; Female; Fenoprofen; Half-Life; Humans; Ibuprofen; Indomethacin; Kinetics; Meclofenamic Acid; Naproxen; Phenylbutazone; Piroxicam; Pregnancy; Thiazines; Tolmetin | 1985 |
Diclofenac in the treatment of painful joints and traumatic tendinitis (including strains and sprains): a brief review.
Topics: Diclofenac; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Joint Diseases; Ketoprofen; Naproxen; Pain; Sprains and Strains; Tendinopathy | 1985 |
Relative toxicities of several nonsteroidal antiinflammatory compounds in primary cultures of rat hepatocytes.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Ibuprofen; Indomethacin; L-Lactate Dehydrogenase; Liver; Propionates; Rats; Rats, Inbred Strains; Time Factors | 1985 |
][A new method for screening of analgesics applied to heat induced inflammatory pain].
Topics: Aminopyrine; Analgesics; Animals; Aspirin; Burns; Drug Evaluation, Preclinical; Flufenamic Acid; Habituation, Psychophysiologic; Hot Temperature; Ibuprofen; Indomethacin; Inflammation; Mefenamic Acid; Phenylbutazone; Pyrroles; Rats | 1974 |
Rat neutrophil activation and effects of lipoxygenase and cyclooxygenase inhibitors.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antigen-Antibody Complex; Antioxidants; Calcimycin; Catechols; Cyclooxygenase Inhibitors; Cytochalasin B; Ibuprofen; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Piroxicam; Pyrazoles; Pyrazolones; Rats; Superoxides; Tetradecanoylphorbol Acetate; Thiazines; Zymosan | 1984 |
Diagnosis and management of bursitis.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Anti-Inflammatory Agents; Bursitis; Chondrocalcinosis; Colchicine; Durapatite; Gout; Humans; Hydroxyapatites; Ibuprofen; Indomethacin; Knee; Shoulder; Staphylococcal Infections; Wounds and Injuries | 1984 |
Inhibition of neutrophil activation by nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Cell Aggregation; Humans; Ibuprofen; In Vitro Techniques; Indomethacin; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Piroxicam; Prostaglandin Antagonists; Superoxides; Thiazines | 1984 |
Role of peptide leukotrienes and their hepatobiliary elimination in endotoxin action.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Bile; Chromones; Dexamethasone; Diethylcarbamazine; Endotoxins; Female; Ibuprofen; Indomethacin; Leukotriene B4; Liver; Metabolic Clearance Rate; Mice; Pyrazoles; Rats; Rats, Inbred Strains; Shock, Septic; SRS-A | 1984 |
Relapse of ulcerative proctocolitis during treatment with non-steroidal anti-inflammatory drugs.
Topics: Adult; Anti-Inflammatory Agents; Colitis, Ulcerative; Female; Flurbiprofen; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Recurrence; Salicylates | 1981 |
Mechanical trauma to bladder epithelium liberates prostanoids which modulate neurotransmission in rabbit detrusor muscle.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bethanechol; Bethanechol Compounds; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Epithelium; Fatty Acids; Ibuprofen; Indomethacin; Male; Muscle Contraction; Neuromuscular Junction; Prostaglandins E; Prostanoic Acids; Rabbits; Synaptic Transmission; Urinary Bladder | 1984 |
On the inhibition of interferon action by inhibitors of fatty acid cyclooxygenase.
Topics: Animals; Cell Line; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ibuprofen; Indomethacin; Interferons; Mice; Oxyphenbutazone; Vesicular stomatitis Indiana virus | 1982 |
Effect of topically applied steroidal and nonsteroidal anti-inflammatory agents on skin repair and regeneration.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Collagen; Hydrocortisone; Ibuprofen; Indomethacin; Keratins; Meclofenamic Acid; Nandrolone; Skin; Swine; Triamcinolone Acetonide; Wound Healing | 1984 |
Pharmacology of thromboxane synthetase inhibitors.
Topics: Animals; Aspirin; Blood Platelets; Dogs; Epoprostenol; Guinea Pigs; Humans; Ibuprofen; Indomethacin; Kinetics; Lung; Methacrylates; Microsomes; Oxidoreductases; Thromboxane-A Synthase | 1983 |
Comparison of thromboxane inhibitors to cyclooxygenase inhibitors on survival in a newborn rat model for group B streptococcal sepsis.
Topics: Animals; Animals, Newborn; Ibuprofen; Indomethacin; Rats; Rats, Inbred Strains; Sepsis; Streptococcal Infections; Streptococcus agalactiae | 1983 |
Involvement of arachidonic acid metabolites in functional disturbances following brain injury.
Topics: Animals; Arachidonic Acids; Brain Injuries; Cerebral Cortex; Dexamethasone; Glucose; Ibuprofen; Indomethacin; Male; Rats; Rats, Inbred Strains | 1983 |
A defect in platelet aggregation in Bartter's syndrome.
Topics: Adolescent; Bartter Syndrome; Child; Cyclic AMP; Diet, Sodium-Restricted; Female; Humans; Hyperaldosteronism; Ibuprofen; Indomethacin; Male; Middle Aged; Platelet Aggregation; Prostaglandin Antagonists; Prostaglandins E | 1980 |
Blockage of partially obstructed coronary arteries with platelet thrombi: comparison between its prevention with cyclooxygenase inhibitors versus prostacyclin.
Topics: Animals; Aorta; Arachidonic Acids; Aspirin; Coronary Vessels; Cyclic AMP; Cyclooxygenase Inhibitors; Dogs; Epoprostenol; Ibuprofen; Indomethacin; Kinetics; Muscle Contraction; Platelet Aggregation; Prostaglandins | 1980 |
Endogenous prostacyclin contributes to the efficacy of a thromboxane synthetase inhibitor for preventing coronary artery thrombosis.
Topics: Acrylates; Animals; Aspirin; Blood Platelets; Coronary Disease; Cyclic AMP; Cyclooxygenase Inhibitors; Dogs; Epoprostenol; Female; Ibuprofen; Indomethacin; Male; Methacrylates; Oxidoreductases; Platelet Aggregation; Prostaglandins; Prostaglandins H; Thromboxane-A Synthase | 1981 |
Evidence for a dual action of converting enzyme inhibitor on blood pressure in normal man.
Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Diet, Sodium-Restricted; Humans; Ibuprofen; Indomethacin; Middle Aged; Posture; Proline; Renin; Saralasin | 1981 |
Inhibition of acid secretion in the rat isolated stomach preparation by 5-hydroxytryptamine.
Topics: Animals; Bethanechol Compounds; Bucladesine; Gastric Juice; Histamine; Ibuprofen; In Vitro Techniques; Indomethacin; Isoproterenol; Male; Methysergide; Pentagastrin; Pyrimidines; Rats; Rats, Inbred Strains; Serotonin; Tetrodotoxin | 1983 |
Postburn immunosuppression in an animal model. II. Restoration of cell-mediated immunity by immunomodulating drugs.
Topics: Animals; Burns; Chlorides; Cimetidine; Cyclophosphamide; Dinitrofluorobenzene; Drug Hypersensitivity; Female; Ibuprofen; Immune Tolerance; Immunity, Cellular; Indomethacin; Lithium; Lithium Chloride; Mice; Mice, Inbred Strains | 1984 |
Gentamicin and indomethacin in the treatment of septic shock: effects on prostacyclin and thromboxane A2 production.
Topics: Animals; Epoprostenol; Fatty Acids, Essential; Female; Fibrin Fibrinogen Degradation Products; Gentamicins; Ibuprofen; Imidazoles; Indomethacin; Macrophages; Male; Peritonitis; Prostaglandins; Prostaglandins F; Rats; Shock, Septic; Thromboxane A2; Thromboxane B2; Thromboxanes | 1983 |
Effects of nonsteroidal anti-inflammatory drugs on renal function in septic dogs.
Topics: Animals; Anti-Inflammatory Agents; Dogs; Escherichia coli Infections; Female; Glomerular Filtration Rate; Ibuprofen; Indomethacin; Kidney; Male; Models, Biological; Peritonitis; Prostaglandin Antagonists; Renal Circulation; Vascular Resistance | 1984 |
Studies of short-term pulmonary and peripheral vascular responses induced in oophorectomized sheep by the infusion of a group B streptococcal extract.
Topics: Animals; Blood Pressure; Castration; Endotoxins; Escherichia coli; Female; Femoral Artery; Hypertension, Pulmonary; Ibuprofen; Indomethacin; Infusions, Parenteral; Prostaglandins; Pulmonary Artery; Sheep; Streptococcal Infections; Streptococcus agalactiae | 1984 |
Inhibition of prostaglandin synthesis restores normal hemodynamics in canine hyperdynamic sepsis.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Disease Models, Animal; Dogs; Escherichia coli Infections; Female; Hemodynamics; Ibuprofen; Indomethacin; Male; Oxygen Consumption; Peritonitis; Prostaglandin Antagonists; Prostaglandins; Sepsis; Shock, Septic; Thromboxane A2 | 1984 |
Influence of certain prostaglandin synthetase inhibitors on cytoplasmic estrogen receptors in the uterus.
Topics: Animals; Binding Sites; Cyclooxygenase Inhibitors; Cytoplasm; Female; Ibuprofen; Indomethacin; Mefenamic Acid; Rats; Rats, Inbred Strains; Receptors, Estrogen; Sulindac; Time Factors; Uterus | 1983 |
Pharmacological effects of non-steroidal antiinflammatory agents on prostaglandin and leukotriene synthesis in mouse peritoneal macrophages.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Ascitic Fluid; Aspirin; Female; Guinea Pigs; Ibuprofen; Indomethacin; Macrophages; Male; Mice; Propionates; Prostaglandins; Pyrazoles; SRS-A; Zymosan | 1983 |
Effects of indomethacin and ibuprofen on cerebral metabolism and blood flow in traumatized brain.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Autoradiography; Brain; Brain Injuries; Cerebrovascular Circulation; Glucose; Ibuprofen; Indomethacin; Male; Prostaglandins; Rats; Rats, Inbred Strains | 1983 |
Use of ibuprofen in unusual circumstances.
Topics: Arthritis, Rheumatoid; Aspirin; Bartter Syndrome; Cyclooxygenase Inhibitors; Digoxin; Drug Hypersensitivity; Drug Interactions; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Kidney; Kinetics; Lithium; Liver; Lupus Erythematosus, Systemic; Mixed Connective Tissue Disease; Phenytoin; Platelet Aggregation; Prostaglandins E; Warfarin | 1984 |
Nonsteroidal anti-inflammatory drugs stimulate 15-lipoxygenase/leukotriene pathway in human polymorphonuclear leukocytes.
Topics: Anti-Inflammatory Agents; Arachidonate Lipoxygenases; Aspirin; Chromatography, High Pressure Liquid; Fatty Acids, Unsaturated; Humans; Ibuprofen; Indomethacin; Kinetics; Lipoxygenase; Neutrophils | 1984 |
Drug prescription patterns for rheumatic disorders in Sweden.
Topics: Administration, Oral; Anti-Inflammatory Agents; Chloroquine; Drug Prescriptions; Drug Utilization; Gold Sodium Thiomalate; Hospitals, University; Humans; Ibuprofen; Indomethacin; Naproxen; Penicillamine; Pharmacy Service, Hospital; Phenylbutazone; Rheumatic Diseases; Rheumatology; Suppositories; Sweden | 1984 |
Role of eicosanoids in the control of renal function in severe hepatic disease.
Topics: Animals; Arachidonic Acids; Aspirin; Dogs; Humans; Ibuprofen; Indomethacin; Kidney; Lipoxygenase; Liver Cirrhosis; Phospholipases; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Regional Blood Flow; Thromboxanes; Vasoconstriction | 1984 |
Sedation produced by prostaglandins is not a nonspecific fatty acid effect.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Dinoprost; Dose-Response Relationship, Drug; Fatty Acids; Hypnotics and Sedatives; Ibuprofen; Indomethacin; Male; Mice; Mice, Inbred Strains; Prostaglandins; Prostaglandins F; Sleep; Time Factors | 1984 |
Characteristics and effect of antiinflammatory drugs on adriamycin-induced inflammation in the mouse paw.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Capillary Permeability; Diphenhydramine; Doxorubicin; Fenclonine; Hydrocortisone; Ibuprofen; Indomethacin; Inflammation; Male; Metiamide; Mice; Time Factors | 1980 |
In vivo interaction of nonsteroidal anti-inflammatory drugs on the locomotion of neutrophils elicited by acute non-specific inflammations in the rat--effect of indomethacin, ibuprofen and flurbiprofen.
Topics: Animals; Anti-Inflammatory Agents; Blood; Calcium Pyrophosphate; Chemotaxis, Leukocyte; Flurbiprofen; Ibuprofen; In Vitro Techniques; Indomethacin; Inflammation; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pleurisy; Rats; Rats, Inbred Strains | 1984 |
A clinical evaluation of the antiarthritic agents.
Topics: Anti-Inflammatory Agents; Antimalarials; Arthritis; Aspirin; Diflunisal; Fenoprofen; Glucocorticoids; Gold; Humans; Ibuprofen; Immunosuppressive Agents; Indomethacin; Naproxen; ortho-Aminobenzoates; Penicillamine; Piroxicam; Prostaglandin Antagonists; Salicylates; Sulindac; Thiazines; Tolmetin | 1984 |
Non-steroidal anti-inflammatory agents and hepatic lipid peroxidation in normal- and carrageenin-treated rats.
Topics: Animals; Anti-Inflammatory Agents; Carbon Tetrachloride Poisoning; Carrageenan; Glutathione; Ibuprofen; Indomethacin; Lipid Peroxides; Liver; Male; Phenylbutazone; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet | 1984 |
Effect on platelet aggregation of oral administration of 10 non-steroidal analgesics to humans.
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Diclofenac; Diflunisal; Epinephrine; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Oxyphenbutazone; Piroxicam; Platelet Aggregation; Thiazines; Time Factors | 1984 |
Inhibition of prostaglandin E synthesis by steroidal and nonsteroidal antiinflammatory drugs in human synovial fibroblast cultures.
Topics: Anti-Inflammatory Agents; Cells, Cultured; Diclofenac; Fibroblasts; Humans; Hyaluronic Acid; Hydrocortisone; Ibuprofen; Indomethacin; Poly I-C; Prostaglandins E; Synovial Membrane | 1984 |
Inhibition of human neutrophil secondary granule discharge by antiinflammatory agents.
Topics: Anti-Inflammatory Agents; Complement C5; Complement C5a; Cytochalasin B; Cytoplasmic Granules; Dose-Response Relationship, Drug; Extracellular Space; Humans; Hydrocortisone; Ibuprofen; Indomethacin; Methylprednisolone; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Transcobalamins | 1984 |
Poisoning after overdose with non-steroidal anti-inflammatory drugs.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Child, Preschool; Diflunisal; Female; Fenoprofen; Feprazone; Humans; Ibuprofen; Indomethacin; Ketoprofen; London; Male; Mefenamic Acid; Naproxen; Oxyphenbutazone; Phenylbutazone; Piroxicam; Thiazines; Tolmetin | 1984 |
Promotion of vascular patency in dermal burns with ibuprofen.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Vessels; Body Fluids; Burns; Fibrinolysis; Freezing; Ibuprofen; Imidazoles; Indomethacin; Prostaglandin Antagonists; Rats; Rats, Inbred Strains; Skin; Thromboxane B2; Time Factors; Wound Healing | 1984 |
The effect of non-steroidal anti-inflammatory drugs on the metabolism of 14C-arachidonic acid by human gingival tissue in vitro.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Anti-Inflammatory Agents; Arachidonic Acids; Carbon Radioisotopes; Gingivitis; Humans; Ibuprofen; Indomethacin; Piroxicam; Prostaglandin Antagonists; Prostaglandins; Thiazines | 1983 |
[The analgesic and antipyretic effects of a non-steroidal anti-inflammatory drug, oxaprozin, in experimental animals].
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Temperature; Dogs; Ibuprofen; Indomethacin; Male; Mice; Oxaprozin; Phenylbutazone; Propionates; Rats | 1984 |
Lack of evidence for a role for prostaglandins in the mediation of impaired urinary concentrating ability in Bartter's syndrome.
Topics: Adolescent; Bartter Syndrome; Female; Humans; Hyperaldosteronism; Ibuprofen; Indomethacin; Kidney Concentrating Ability; Middle Aged; Osmolar Concentration; Potassium; Prostaglandins; Urine | 1983 |
Influence of non-steroidal anti-inflammatory agents on tolbutamide hypoglycaemia.
Topics: Animals; Anti-Inflammatory Agents; Female; Humans; Hypoglycemia; Ibuprofen; Indomethacin; Male; ortho-Aminobenzoates; Phenylbutazone; Rabbits; Tolbutamide | 1983 |
Comparative effects of indomethacin, prostaglandin E1, and ibuprofen on bowel ischemia.
Topics: Alprostadil; Animals; Ductus Arteriosus, Patent; Enterocolitis, Pseudomembranous; Ibuprofen; Indomethacin; Intestine, Small; Ischemia; Prostaglandins E; Rats; Rats, Inbred Strains; Risk | 1983 |
Nonsteroidal anti-inflammatory drugs and renal disease.
Topics: Anti-Inflammatory Agents; Blood Urea Nitrogen; Depression, Chemical; Humans; Ibuprofen; Indomethacin; Kidney; Phenylbutazone; Prostaglandins E; Renal Circulation | 1984 |
The prevention of adhesion formation by nonsteroidal antiinflammatory drugs: an animal study comparing ibuprofen and indomethacin.
Topics: Animals; Fallopian Tube Diseases; Fallopian Tubes; Female; Guinea Pigs; Ibuprofen; Indomethacin; Postoperative Complications; Tissue Adhesions | 1984 |
Hematuria and the use of nonsteroidal anti-inflammatory drugs.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Female; Hematuria; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen | 1984 |
Effects of prostaglandins on the cerebral circulation in the coat.
Topics: Animals; Cerebrovascular Circulation; Dinoprost; Dinoprostone; Epoprostenol; Female; Goats; Hypercapnia; Ibuprofen; Indomethacin; Prostaglandins; Prostaglandins E; Prostaglandins F | 1982 |
Comparative gastric ulcerogenic effects of meseclazone, 5-chlorosalicylic acid and other nonsteroidal anti-inflammatory drugs following acute and repeated oral administration to rats.
Topics: Animals; Anti-Inflammatory Agents; Benzoxazines; Biotransformation; Fenoprofen; Ibuprofen; Indomethacin; Male; Naproxen; Oxazines; Peptic Ulcer Hemorrhage; Phenylbutazone; Rats; Salicylates; Stomach Ulcer; Time Factors; Tolmetin | 1980 |
Dysmenorrhoea: effective new approaches to a controversial problem.
Topics: Cyclooxygenase Inhibitors; Dysmenorrhea; Female; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Naproxen | 1980 |
[Prevention of food hypersensitivities with aspirin].
Topics: Animals; Arachidonic Acids; Aspirin; Asthma; Food Hypersensitivity; Ibuprofen; Indomethacin; Milk; Prostaglandin Antagonists; Shellfish | 1980 |
[Evaluation of the effect of ibuprofen lysinate on lymphocytic transformation in vitro. Comparison with meglumine indomethacinate, phenylbutazone, and lysine acetylsalicylate].
Topics: Anti-Inflammatory Agents; Aspirin; Humans; Ibuprofen; Indomethacin; Lymphocyte Activation; Lysine; Meglumine; Phenylbutazone | 1980 |
The bleeding time is longer than normal in hemophilia.
Topics: Adolescent; Adult; Aged; Bleeding Time; Child; Child, Preschool; Factor VIII; Hemophilia A; Humans; Ibuprofen; Indomethacin; Middle Aged; von Willebrand Factor | 1981 |
Relationship between cyclooxygenase activity (COA) inhibition and stimulation of ventilation by salicylate.
Topics: Animals; Cyclooxygenase Inhibitors; Dogs; Dose-Response Relationship, Drug; Hydroxybenzoates; Ibuprofen; Indomethacin; Infusions, Intra-Arterial; Respiration; Salicylates; Sodium Chloride; Sodium Salicylate | 1981 |
Interaction of calcium and cyclooxygenase inhibitors on transport by the turtle and toad bladders.
Topics: Animals; Biological Transport, Active; Body Water; Bufo marinus; Calcium; Cyclooxygenase Inhibitors; Dinoprostone; Hydrogen; Ibuprofen; In Vitro Techniques; Indomethacin; Prostaglandins E; Sodium; Turtles; Urinary Bladder; Vasopressins | 1982 |
Prostaglandin synthetase inhibitors in primary herpes infections.
Topics: Adolescent; Adult; Child, Preschool; Cyclooxygenase Inhibitors; Female; Herpes Simplex; Humans; Ibuprofen; Indomethacin; Male | 1980 |
Effect of nonsteroidal antiinflammatory drugs on human monocyte chemotaxis in vitro.
Topics: Anti-Inflammatory Agents; Cell Survival; Chemotaxis, Leukocyte; Humans; Ibuprofen; Indomethacin; Monocytes; Naproxen | 1983 |
Identification of risk for renal insufficiency from nonsteroidal anti-inflammatory drugs.
Topics: Acute Kidney Injury; Adult; Age Factors; Aged; Anti-Inflammatory Agents; Arteriosclerosis; Blood Urea Nitrogen; Creatinine; Diabetic Nephropathies; Diuretics; Female; Humans; Hypertension, Renal; Ibuprofen; Indomethacin; Male; Middle Aged; Potassium; Risk; Sodium | 1983 |
Renal papillary necrosis following regular consumption of non-steroidal anti-inflammatory drugs.
Topics: Aged; Anti-Inflammatory Agents; Humans; Ibuprofen; Indomethacin; Ketoprofen; Kidney Papillary Necrosis; Male; Middle Aged; Naproxen; Osteoarthritis | 1982 |
Implications for thromboxane A2 in the pathogenesis of endotoxic shock.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprost; Disseminated Intravascular Coagulation; Fibrin Fibrinogen Degradation Products; Ibuprofen; Indomethacin; Male; Muridae; Prostaglandins E; Prostaglandins F; Shock, Septic; Thromboxane A2; Thromboxanes | 1981 |
Rheumatoid arthritis IV: non-steroidal anti-inflammatory agents use in treatment.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Fenoprofen; Humans; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone; Tolmetin | 1982 |
Reintroduction of anti-inflammatory drug therapy after drug-associated gastro-intestinal disturbances.
Topics: Administration, Oral; Aged; Anti-Inflammatory Agents; Arthritis; Duodenal Ulcer; Female; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Osteoarthritis; Peptic Ulcer; Peptic Ulcer Hemorrhage; Recurrence; Retrospective Studies; Salicylates; Suppositories; Time Factors | 1982 |
The role of prostaglandins in endotoxemia: comparisons in response in the nonpregnant, maternal, and fetal models. I. Prostaglandins and the pulmonary effect of experimental endotoxemia.
Topics: Animals; Castration; Endotoxins; Escherichia coli; Female; Hypertension, Pulmonary; Ibuprofen; Indomethacin; Methylprednisolone; Prostaglandins E; Prostaglandins F; Respiratory Distress Syndrome; Sheep; Toxemia | 1980 |
Inactive renin and prostaglandin E2 production in hyporeninemic hypoaldosteronism.
Topics: Aldosterone; Enzyme Activation; Female; Humans; Ibuprofen; Indomethacin; Male; Posture; Prostaglandins E; Renin | 1980 |
Inhibition of prostaglandin E synthesis augments glucose-induced insulin secretion is cultured pancreas.
Topics: Animals; Cells, Cultured; Glucose; Ibuprofen; Indomethacin; Insulin; Insulin Secretion; Islets of Langerhans; Prostaglandins E; Rats; Sodium Salicylate | 1981 |
Improved survival in the suckling rat model of group B streptococcal sepsis after treatment with nonsteroidal anti-inflammatory drugs.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Rats; Rats, Inbred Strains; Streptococcal Infections; Streptococcus agalactiae | 1982 |
Blood flow reductions in stenosed canine coronary arteries: vasospasm or platelet aggregation?
Topics: Animals; Aspirin; Constriction, Pathologic; Coronary Angiography; Coronary Circulation; Coronary Disease; Coronary Vasospasm; Disease Models, Animal; Dogs; Heparin; Ibuprofen; Indomethacin; Platelet Aggregation | 1982 |
Ethanol potentiation of aspirin-induced prolongation of the bleeding time.
Topics: Adult; Alcoholic Beverages; Aspirin; Bleeding Time; Drug Synergism; Female; Hemostasis; Humans; Ibuprofen; Indomethacin; Male; Platelet Function Tests; Time Factors | 1982 |
[Effect of the immunodepressants chrisanol, brufen and indomethacin on synovial membrane permeability in rheumatoid arthritis].
Topics: Adult; Arthritis, Rheumatoid; Capillary Permeability; Cell Membrane Permeability; Dimercaprol; Drug Therapy, Combination; Female; Gold; Humans; Ibuprofen; Immunosuppressive Agents; Indomethacin; Male; Middle Aged; Organogold Compounds; Organometallic Compounds; Propanols; Sulfhydryl Compounds; Synovial Membrane | 1982 |
Reduction of the erythema response to ultraviolet light by nonsteroidal antiinflammatory agents.
Topics: Anti-Inflammatory Agents; Aspirin; Erythema; Humans; Ibuprofen; Indomethacin; Ultraviolet Rays | 1982 |
Pharmacotherapy of juvenile rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Antimalarials; Arthritis, Juvenile; Chemical and Drug Induced Liver Injury; Child; Delayed-Action Preparations; Gold; Humans; Ibuprofen; Indomethacin; Penicillamine; Salicylates; Sulindac; Tolmetin | 1981 |
Experimental evidence for involvement of prostaglandins in viability and acute skin flaps: effects on viability and mode of action.
Topics: Abdomen; Acute Disease; Animals; Ibuprofen; Indomethacin; Male; Mathematics; Prostaglandins; Rats; Skin; Surgical Flaps | 1981 |
Indomethacin, ibuprofen and meclofenamate inhibit adenosine uptake by rat brain synaptosomes.
Topics: Adenosine; Animals; Anti-Inflammatory Agents; Brain; Ibuprofen; In Vitro Techniques; Indomethacin; Meclofenamic Acid; Rats; Synaptosomes | 1981 |
[Lipid peroxidation in the rat liver after acute inflammation induced by carrageenan. I. Influence of non-steroidal anti-inflammatory agents].
Topics: Animals; Carbon Tetrachloride; Carrageenan; Edema; Ibuprofen; Indomethacin; Inflammation; Lipid Peroxides; Liver; Male; Phenylbutazone; Rats; Rats, Inbred Strains | 1981 |
[Effect of non-steroid anti-inflammatory agents--indomethacin and brufen--on water-salt metabolism].
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Glomerulonephritis; Humans; Ibuprofen; Indomethacin; Middle Aged; Potassium; Sodium; Water-Electrolyte Balance | 1981 |
Differential effects of ibuprofen and indomethacin in the regional circulation of the dog.
Topics: Animals; Aorta; Blood Pressure; Cyproheptadine; Dogs; Female; Ibuprofen; Indomethacin; Male; Phentolamine; Prostaglandins; Regional Blood Flow; Renal Circulation; Splanchnic Circulation; Tachyphylaxis | 1981 |
Effect of intrauterine administration of antiprostaglandin drugs on implantation in the rat.
Topics: Animals; Aspirin; Embryo Implantation; Female; Ibuprofen; Indomethacin; Injections; Pregnancy; Prostaglandin Antagonists; Rats; Time Factors; Uterus | 1981 |
[The role of prostaglandins in the pathogenesis of Bartter's syndrome].
Topics: Adult; Bartter Syndrome; Humans; Hyperaldosteronism; Ibuprofen; Indomethacin; Male; Prostaglandin Antagonists; Prostaglandins | 1981 |
Effective of acetylsalicylic acid, indomethacin, phenylbutazone, paracetamol, ibuprofen and naproxen on canine gastric mucosa: a histological and ultrastructural study.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Aspirin; Dogs; Gastric Mucosa; Ibuprofen; Indomethacin; Naproxen; Phenylbutazone | 1981 |
Lactose intolerance.
Topics: Aspirin; Child; Humans; Ibuprofen; Indomethacin; Infant; Lactose Intolerance; Prostaglandins | 1980 |
Activation of latent tuberculosis by nonsteroidal anti-inflammatory agents.
Topics: Female; Humans; Ibuprofen; Indomethacin; Middle Aged; Tuberculosis, Pulmonary | 1980 |
Effects of selected drugs on serum digoxin concentration in dogs.
Topics: Acetaminophen; Animals; Aspirin; Digoxin; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Ibuprofen; Indomethacin; Male; Metabolic Clearance Rate; Quinidine; Quinine; Time Factors | 1980 |
Effects of dialyzable leukocyte extracts (DLE) with transfer factor activity on leukocyte migration in vitro. IV. Two distinct effects of DLE on leukocyte migration can be produced by prostaglandins.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Anti-Inflammatory Agents; Antigens; Cell Migration Inhibition; Dialysis; Humans; Ibuprofen; Immunity, Cellular; Indomethacin; Leukocytes; Mefenamic Acid; Molecular Weight; Neutrophils; Prostaglandins; Prostaglandins A; Prostaglandins E; Prostaglandins F; Transfer Factor; Tuberculin | 1980 |
Concanavalin A-induced transformation of mononuclear cells: influence of plasma from patients receiving anti-inflammatory agents.
Topics: Bone Diseases; Cells, Cultured; Concanavalin A; Culture Media; Humans; Ibuprofen; Indomethacin; Lymphocyte Activation; Phenylbutazone; Plasma; Prostaglandins | 1980 |
Effects of some nonsteroidal antiinflammatory drugs on proteoglycan metabolism and organization in canine articular cartilage.
Topics: Animals; Anti-Inflammatory Agents; Cartilage, Articular; Dogs; Fenoprofen; Glycosaminoglycans; Ibuprofen; Indomethacin; Protein Biosynthesis; Proteoglycans; Sulindac | 1980 |
The effect of prostaglandin synthesis inhibitors and diphosphonates on tumour-mediated osteolysis.
Topics: Animals; Bone Resorption; Breast Neoplasms; Culture Techniques; Diphosphonates; Flurbiprofen; Humans; Ibuprofen; Indomethacin; Mice; Neoplasms, Experimental; Osteolysis; Prostaglandin Antagonists | 1980 |
Interaction of indomethacin and ibuprofen with lithium in manic patients under a steady-state lithium level.
Topics: Adult; Affective Disorders, Psychotic; Bipolar Disorder; Drug Interactions; Drug Therapy, Combination; Female; Humans; Ibuprofen; Indomethacin; Lithium; Male; Middle Aged | 1980 |
[Hematotoxic lesions caused by non-steroidal antirheumatic agents].
Topics: Adult; Aged; Agranulocytosis; Anemia, Aplastic; Arthritis, Rheumatoid; Aspirin; Diclofenac; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Penicillamine; Phenylbutazone; Thrombocytopenia | 1980 |
Inhibitory effect of NSAIDs on the chemotaxis induced by substance P on human monocytes and polymorphonuclear cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Aspirin; Chemotaxis, Leukocyte; Diclofenac; Humans; Ibuprofen; Indomethacin; Leukocytes; Monocytes; Neutrophils; Piroxicam; Substance P | 1993 |
Nonsteroidal anti-inflammatory drugs inhibit expression of the inducible nitric oxide synthase gene.
Topics: Amino Acid Oxidoreductases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line; Dose-Response Relationship, Drug; Enzyme Induction; Gene Expression; Ibuprofen; Indomethacin; Isoenzymes; Kinetics; Macrophages, Alveolar; Nitric Oxide Synthase; Rats; Sodium Salicylate | 1995 |
Mechanisms of bradykinin-induced contraction of the guinea-pig gallbladder in vitro.
Topics: Animals; Bradykinin; Dinoprostone; Dose-Response Relationship, Drug; Female; Gallbladder; Guinea Pigs; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Potassium Compounds; Receptors, Bradykinin | 1995 |
Ibuprofen treatment of patent ductus arteriosus.
Topics: Brain; Cerebrovascular Circulation; Ductus Arteriosus, Patent; Gestational Age; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Infusions, Intravenous | 1995 |
[Effect of prostaglandin inhibitors on leukocyte infiltration and on leukocytes in tears after experimental injury of the corneal epithelium].
Topics: Animals; Cornea; Epithelium; Ibuprofen; Indomethacin; Leukocyte Count; Leukocytes; Prostaglandin Antagonists; Rabbits; Regeneration; Tears | 1995 |
Alterations in the electroretinogram of newborn piglets by propionic acid-derivative nonsteroidal antiinflammatory drugs but not by indomethacin and diclofenac.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Electroretinography; Flurbiprofen; Ibuprofen; Indomethacin; Naproxen; Photoreceptor Cells; Propionates; Prostaglandins; Retina; Swine | 1995 |
The role of arachidonic acid and/or its metabolites in embryo implantation initiated by epidermal growth factor (EGF).
Topics: Animals; Arachidonic Acid; Dexamethasone; Dinoprostone; Embryo Implantation; Epidermal Growth Factor; Female; Histamine; Hypophysectomy; Ibuprofen; Indomethacin; Pregnancy; Progesterone; Rats; Uterus | 1995 |
Up-regulation of brain PGE2 and PGF2 alpha receptors and receptor-coupled second messengers by cyclooxygenase inhibition in newborn pigs.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Animals, Newborn; Brain; Cyclic AMP; Ibuprofen; In Vitro Techniques; Indomethacin; Inositol 1,4,5-Trisphosphate; Prostaglandins F, Synthetic; Receptors, Prostaglandin; Receptors, Prostaglandin E; Second Messenger Systems; Swine; Synaptosomes; Up-Regulation | 1995 |
Effects of nonsteroidal antiinflammatory drugs on ulcerogenesis and gastric secretion in pylorus-ligated rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dinoprostone; Gastric Acid; Gastric Mucosa; Histamine; Ibuprofen; Indomethacin; Ligation; Male; Pepsinogens; Pylorus; Ranitidine; Rats; Rats, Sprague-Dawley; Salicylates; Stomach Ulcer | 1995 |
Cyclooxygenase inhibitors enhance tumour necrosis factor production and mortality in murine endotoxic shock.
Topics: Animals; Cyclooxygenase Inhibitors; Death; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Ibuprofen; Indomethacin; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Shock, Septic; Time Factors; Tumor Necrosis Factor-alpha | 1994 |
Characterization and mechanism of side-effects of Oxygent HT (highly concentrated fluorocarbon emulsion) in swine.
Topics: Animals; Blood Substitutes; Dexamethasone; Emulsions; Fluorocarbons; Hydrocarbons, Brominated; Ibuprofen; Indomethacin; Macrophages, Alveolar; Pyrogens; Swine | 1994 |
Calcitonin gene-related peptide release in endotoxicosis may be mediated by prostaglandins.
Topics: Animals; Aspirin; Blood Glucose; Blood Pressure; Calcitonin Gene-Related Peptide; Cyclooxygenase Inhibitors; Drug Tolerance; Ibuprofen; Imidazoles; Indomethacin; Lactates; Lipopolysaccharides; Male; Prostaglandins; Rats; Rats, Sprague-Dawley; Rats, Wistar; Shock, Septic; Thromboxanes | 1995 |
A simple microassay for computing the hemolytic potency of drugs.
Topics: Animals; Electronic Data Processing; Erythrocytes; Flufenamic Acid; Hemolysis; Ibuprofen; Indomethacin; Mice; Numerical Analysis, Computer-Assisted; Sensitivity and Specificity | 1994 |
Evidence that prostaglandins modulate lipogenesis in cultured lymphocytes--a comparison with its effect on macrophages and tumour cells.
Topics: Acetates; Animals; Arachidonic Acid; Carbon Radioisotopes; Cells, Cultured; Concanavalin A; DNA; DNA, Neoplasm; HeLa Cells; Humans; Ibuprofen; Indomethacin; KB Cells; Lipids; Lymphocyte Activation; Lymphocytes; Macrophages, Peritoneal; Neoplasms; Neoplasms, Experimental; Prostaglandins; Pyruvates; Pyruvic Acid; Rats; Thymidine; Tumor Cells, Cultured | 1994 |
Involvement of both cyclooxygenase and lipoxygenase pathways in platelet-activating factor-induced interleukin-6 production by alveolar macrophages.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Arachidonate 5-Lipoxygenase; Aspirin; Bucladesine; Cyclooxygenase Inhibitors; Dinoprostone; Ibuprofen; Indomethacin; Interleukin-6; Leukotriene B4; Macrophages, Alveolar; Male; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 1994 |
High-performance liquid chromatographic assay for ibuprofen in whole blood using solid-phase extraction.
Topics: Animals; Chromatography, High Pressure Liquid; Ibuprofen; Indicators and Reagents; Indomethacin; Injections, Intravenous; Rabbits; Spectrophotometry, Ultraviolet | 1994 |
Interleukin-1 beta and interleukin-6 stimulate neurohypophysial hormone release in vitro.
Topics: Animals; Arginine Vasopressin; Benzeneacetamides; Hydroxamic Acids; Ibuprofen; In Vitro Techniques; Indomethacin; Interleukin-1; Interleukin-6; Lipoxygenase Inhibitors; Male; Oxytocin; Pituitary Gland, Posterior; Pituitary Hormones, Posterior; Potassium Chloride; Rats; Rats, Wistar; Stimulation, Chemical | 1994 |
The cyclooxygenase and lipoxygenase inhibitor BW755C protects rats against kainic acid-induced seizures and neurotoxicity.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoles; Brain; Choline O-Acetyltransferase; Cyclooxygenase Inhibitors; Glutamate Decarboxylase; Ibuprofen; Indomethacin; Isoindoles; Kainic Acid; Lipoxygenase Inhibitors; Male; Organ Specificity; Organoselenium Compounds; Rats; Rats, Sprague-Dawley; Seizures | 1994 |
Protection by indomethacin against the lethality and hepatotoxicity of phalloidin in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Aspirin; Chemical and Drug Induced Liver Injury; Female; Ibuprofen; Indomethacin; Liver; Liver Diseases; Mice; Microscopy, Electron; Phalloidine; Time Factors | 1994 |
The determination of non-steroidal antiinflammatory drugs in pharmaceuticals by capillary zone electrophoresis and micellar electrokinetic capillary chromatography.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Buffers; Calibration; Chemistry, Pharmaceutical; Chromatography; Diclofenac; Dosage Forms; Electrophoresis; Ibuprofen; Indomethacin; Ketoprofen; Micelles; Piroxicam; Reference Standards; Regression Analysis; Reproducibility of Results | 1994 |
Indomethacin-sensitive CO2 reactivity of cerebral arterioles is restored by vasodilator prostaglandin.
Topics: Animals; Animals, Newborn; Arterioles; Carbon Dioxide; Cerebrovascular Circulation; Ibuprofen; Indomethacin; Pia Mater; Prostaglandins; Swine; Vasodilator Agents | 1994 |
Dissociation of the anti-ischaemic effects of cloricromene from its anti-platelet activity.
Topics: Animals; Blood Pressure; Chromonar; Coronary Vessels; Electrocardiography; Heart Rate; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Muscle, Smooth, Vascular; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Neutrophils; Peroxidase; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Ventricular Pressure | 1993 |
Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Aspirin; Blotting, Western; Cattle; Cell Line; Cell Survival; Cyclooxygenase Inhibitors; Eicosanoids; Endothelium, Vascular; Enzyme Induction; Ibuprofen; Indomethacin; Kinetics; Macrophages; Mice; Models, Biological; Prostaglandin-Endoperoxide Synthases; Sodium Salicylate | 1993 |
Diffusion and concentration profiles of drugs in gels.
Topics: Acetaminophen; Chlorpheniramine; Diffusion; Gels; Humans; Ibuprofen; Indomethacin; Pharmacokinetics; Temperature; Theophylline | 1993 |
Effects of nonsteroidal anti-inflammatory drugs on microvascular dynamics.
Topics: Administration, Topical; Animals; Endothelium, Vascular; Ibuprofen; Indomethacin; Inflammation; Leukocytes; Male; Microcirculation; Microscopy; Rats; Rats, Wistar; Splanchnic Circulation; Venules | 1993 |
NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Cyclooxygenase Inhibitors; Diclofenac; Edema; Fever; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Nitrobenzenes; Pain; Phenylpropionates; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Stomach Ulcer; Sulfonamides | 1993 |
Glycogenolytic and haemodynamic responses to bovine serum albumin in isolated perfused livers from sensitized rats.
Topics: Animals; Azepines; Calcium; Glycogen; Hemodynamics; Ibuprofen; In Vitro Techniques; Indomethacin; Lactates; Lactic Acid; Liver; Male; Perfusion; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Triazoles | 1993 |
Indomethacin compromises hemodynamics during positive-pressure ventilation, independently of prostanoids.
Topics: Animals; Animals, Newborn; Blood Pressure; Cardiac Output; Heart Rate; Hemodynamics; Ibuprofen; Indomethacin; Positive-Pressure Respiration; Prostaglandins; Regional Blood Flow; Respiratory Mechanics; Swine | 1993 |
Effect of nonsteroidal antiinflammatory drugs on fracture healing: a laboratory study in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomechanical Phenomena; Bony Callus; Female; Femoral Fractures; Fracture Healing; Ibuprofen; Indomethacin; Rats | 1995 |
Do non-steroidal anti-inflammatory drugs have an effect on gastric cell turnover?
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Bromodeoxyuridine; Cell Division; Diclofenac; Gastric Mucosa; Gastroscopy; Humans; Ibuprofen; Immunohistochemistry; Indomethacin; Mefenamic Acid; Naproxen; Pyloric Antrum | 1995 |
Cost savings using a stepped-care prescribing protocol for nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Protocols; Cost Savings; District of Columbia; Drug Costs; Drug Utilization Review; Hospital Costs; Hospitals, Military; Humans; Ibuprofen; Indomethacin | 1996 |
Effect of hypoxia on release of IL-1 and TNF by human alveolar macrophages.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Northern; Cell Hypoxia; Dinoprostone; Humans; Ibuprofen; Indomethacin; Interleukin-1; Lipopolysaccharides; Macrophages, Alveolar; Rabbits; RNA, Messenger; Tumor Necrosis Factor-alpha | 1996 |
Enhancement by cyclo-oxygenase inhibitors of platelet-activating factor production in thapsigargin-stimulated macrophages.
Topics: Animals; Arachidonic Acid; Bucladesine; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Ibuprofen; Indomethacin; Macrophages, Peritoneal; Male; Naproxen; Platelet Activating Factor; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Terpenes; Thapsigargin | 1995 |
Induction of cytochrome P-450 BM-3 (CYP 102) by non-steroidal anti-inflammatory drugs in Bacillus megaterium.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacillus megaterium; Bacterial Proteins; Base Sequence; Cytochrome P-450 Enzyme System; Enzyme Induction; Gene Expression; Ibuprofen; Indomethacin; Ketoprofen; Kinetics; Mammals; Mixed Function Oxygenases; Molecular Sequence Data; NADPH-Ferrihemoprotein Reductase; Oligodeoxyribonucleotides; Repressor Proteins; Transcription Factors | 1996 |
Mechanism of selective inhibition of human prostaglandin G/H synthase-1 and -2 in intact cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Ibuprofen; Indomethacin; Prostaglandin-Endoperoxide Synthases; Prostaglandins | 1996 |
Comparative effects of selective cyclooxygenase 1 and cyclooxygenase 2 inhibitors on myeloperoxidase and 3 alpha-hydroxysteroid dehydrogenase.
Topics: 3-Hydroxysteroid Dehydrogenases; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Humans; Ibuprofen; Indomethacin; Isoenzymes; Kinetics; Leukocytes; Membrane Proteins; Peroxidase; Polycyclic Aromatic Hydrocarbons; Prostaglandin-Endoperoxide Synthases; Recombinant Proteins | 1996 |
Increased use of cardiovascular medications in seniors prescribed non-ASA non-steroidal anti-inflammatory drugs.
Topics: Age Factors; Aged; Alberta; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Humans; Ibuprofen; Indomethacin; Retrospective Studies; Risk Factors | 1996 |
Modulation of 8-methoxypsoralen-photoinduced cutaneous inflammatory reactions by various chemotherapeutic agents in vivo.
Topics: Acetophenones; Animals; Capillary Permeability; Erythema; Ibuprofen; Indoles; Indomethacin; Masoprocol; Methoxsalen; Neutrophils; PUVA Therapy; Quinacrine; Rabbits; Skin | 1996 |
Assessment of the antiexudative and antiproliferative activities of non-steroidal anti-inflammatory drugs in inflammatory models developed in rats by subcutaneous implantation of bacterial cell walls from the dental plaque.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Cell Division; Cell Wall; Child; Dental Plaque; DNA Replication; Duodenum; Edema; Exudates and Transudates; Granuloma; Growth Inhibitors; Humans; Ibuprofen; Indomethacin; Inflammation; Intestinal Mucosa; Naproxen; Rats; Sulindac | 1996 |
Interaction of ibuprofen and indomethacin with caffeine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Central Nervous System Stimulants; Chemical Phenomena; Chemistry, Physical; Ibuprofen; Indomethacin; Male; Rats; Skin Absorption; Solubility; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 1996 |
Peroxisome proliferator-activated receptors alpha and gamma are activated by indomethacin and other non-steroidal anti-inflammatory drugs.
Topics: Adipose Tissue; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Differentiation; Humans; Ibuprofen; Indomethacin; Liver; Mice; Mice, Inbred C3H; Microbodies; Nuclear Proteins; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 1997 |
Effects of nimesulide, a preferential cyclooxygenase-2 inhibitor, on carrageenan-induced pleurisy and stress-induced gastric lesions in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Excipients; Exudates and Transudates; Gastric Mucosa; Gastritis; Ibuprofen; Indomethacin; Isoenzymes; Male; Membrane Proteins; Pleurisy; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Stress, Physiological; Sulfonamides | 1996 |
Effects of non-steroidal anti-inflammatory drugs on prostaglandin E2 production by cyclooxygenase-2 from endogenous and exogenous arachidonic acid in rat peritoneal macrophages stimulated with lipopolysaccharide.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Ibuprofen; Indomethacin; Isoenzymes; Lipopolysaccharides; Macrophages, Peritoneal; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Sulfonamides | 1996 |
Cerebral arteriolar dilation to hypoxia: role of prostanoids.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Animals, Newborn; Arterioles; Cerebrovascular Circulation; Hypercapnia; Hypoxia; Ibuprofen; Indomethacin; Pia Mater; Prostaglandins; Swine; Vasoconstriction; Vasodilation | 1997 |
Effects of nonsteroidal anti-inflammatory drugs on glutathione S-transferases of the rat digestive tract.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Cytosol; Digestive System; Dose-Response Relationship, Drug; Enzyme Induction; Esophagus; Glutathione; Glutathione Transferase; Ibuprofen; Indomethacin; Intestines; Isoenzymes; Liver; Male; Organ Specificity; Piroxicam; Rats; Rats, Wistar; Stomach; Substrate Specificity; Sulindac | 1997 |
Potentiation by indomethacin of receptor-mediated catecholamine secretion in rat adrenal medulla.
Topics: Adrenal Medulla; Animals; Arachidonic Acid; Bradykinin; Calcium; Catecholamines; Chromaffin Granules; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Fluorescent Dyes; Histamine; Ibuprofen; Indoles; Indomethacin; Male; Muscarine; Muscarinic Agonists; Nicotine; Oxytocics; Potassium; Rats; Rats, Wistar | 1997 |
Delayed release of prostaglandins from arachidonic acid and kinetic changes in prostaglandin H synthase activity on the induction of prostaglandin H synthase-2 after lipopolysaccharide-treatment of RAW264.7 macrophage-like cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cell Line; Enzyme Induction; Escherichia coli; Ibuprofen; Indomethacin; Isoenzymes; Kinetics; Lipopolysaccharides; Macrophages; Mice; Prostaglandin-Endoperoxide Synthases; Prostaglandins | 1997 |
Characteristics of coronary endothelial dysfunction in experimental diabetes.
Topics: Acetylcholine; Animals; Arginine; Coronary Circulation; Coronary Vessels; Cyclic GMP; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Nitric Oxide; Nitroprusside; Vasodilation; Vasodilator Agents | 1997 |
[HPLC analysis of non-steroidal antirheumatic agents in biological material. II. Profens].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Ibuprofen; Indomethacin; Rabbits | 1997 |
Apoptosis induced by NS-398, a selective cyclooxygenase-2 inhibitor, in human colorectal cancer cell lines.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Division; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; DNA Fragmentation; Dose-Response Relationship, Drug; Humans; Ibuprofen; Indomethacin; Isoenzymes; Membrane Proteins; Nitrobenzenes; Piroxicam; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Tumor Cells, Cultured | 1997 |
Stimulus dependence of non-steroidal antiinflammatory drug potency in a cellular assay of prostaglandin H synthase-2.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Drug Interactions; Humans; Ibuprofen; Indans; Indomethacin; Interleukin-1; Meclofenamic Acid; Nitrobenzenes; Okadaic Acid; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Sulfonamides; Tumor Necrosis Factor-alpha | 1997 |
Inhibition by piroxicam of oxidative DNA damage, liver cirrhosis and development of enzyme-altered nodules caused by a choline-deficient, L-amino acid-defined diet in rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Choline; Cyclooxygenase Inhibitors; Deoxyguanosine; DNA Damage; Drinking; Feeding Behavior; Food, Formulated; gamma-Glutamyltransferase; Glutathione Transferase; Ibuprofen; Indomethacin; Liver; Liver Cirrhosis, Experimental; Male; Piroxicam; Rats; Rats, Inbred F344 | 1997 |
Stimulation of adipose differentiation related protein (ADRP) expression by ibuprofen and indomethacin in adipocyte precursors and in adipocytes.
Topics: Adipocytes; Adipose Tissue; Animals; Cell Differentiation; Cells, Cultured; Cyclooxygenase Inhibitors; Ibuprofen; Indomethacin; Membrane Proteins; Mice; Molecular Weight; Perilipin-2; RNA, Messenger; Transcriptional Activation | 1998 |
Effects of non-steroidal anti-inflammatory drugs and cyclooxygenase-2 specific inhibitors on mediator release from rat peritoneal mast cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Enzyme Activation; Flurbiprofen; Histamine Release; Ibuprofen; Immunoglobulin E; Indans; Indomethacin; Isoenzymes; Male; Mast Cells; Naphthaleneacetic Acids; Nitrobenzenes; Peritoneal Cavity; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Sulfonamides | 1998 |
Prodrugs. Part 3. 2-Formylphenyl esters of indomethacin, ketoprofen and ibuprofen and 6-substituted 2-formyl and 2-acylphenyl esters of aspirin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ibuprofen; Indomethacin; Ketoprofen; Male; Prodrugs; Rats; Rats, Wistar | 1998 |
Gamma-linolenic acid (GLA) is cytotoxic to 36B10 malignant rat astrocytoma cells but not to 'normal' rat astrocytes.
Topics: alpha-Linolenic Acid; Animals; Antineoplastic Agents; Antioxidants; Astrocytes; Astrocytoma; Brain Neoplasms; Cell Death; Chromans; Cyclooxygenase Inhibitors; Dinoprost; F2-Isoprostanes; gamma-Linolenic Acid; Ibuprofen; Indomethacin; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured; Vitamin E | 1998 |
Influence of acute uraemia on percutaneous absorption of nonsteroidal anti-inflammatory drugs.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Indomethacin; Male; Rats; Rats, Wistar; Skin Absorption; Uremia | 1998 |
Store-operated calcium influx in human gastric cells: role of endogenous prostaglandins.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biological Transport; Calcium; Calcium Channel Blockers; Cell Communication; Cell Line; Dinoprostone; Enzyme Inhibitors; Gastric Mucosa; Humans; Ibuprofen; Indomethacin; Lanthanum; Manganese; Nifedipine; Prostaglandin Antagonists; Thapsigargin; Verapamil | 1998 |
Nonsteroidal anti-inflammatory drugs enhance glutathione S-transferase theta levels in rat colon.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Butanones; Colon; Colonic Neoplasms; Diet; Glutathione Transferase; Ibuprofen; Indomethacin; Male; Nabumetone; Piroxicam; Rats; Rats, Wistar; Sulindac | 1998 |
Anti-inflammatory activity of chondroitin sulfate.
Topics: Administration, Oral; Aged; Animals; Anti-Inflammatory Agents; Chondroitin Sulfates; Feces; Female; Humans; Ibuprofen; Indomethacin; Injections, Intravenous; Leukocytes; Male; Middle Aged; Osteoarthritis; Rats; Synovial Fluid; Time Factors; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 1998 |
Nonsteroidal anti-inflammatory drugs increase tumor necrosis factor production in the periphery but not in the central nervous system in mice and rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Brain; Brain Ischemia; Encephalomyelitis, Autoimmune, Experimental; Ibuprofen; Indomethacin; Joints; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred Strains; Rats; Rats, Sprague-Dawley; Spleen; Tumor Necrosis Factor-alpha | 1998 |
Anti-inflammatory drugs interacting with Zn(II), Cd(II) and Pt(II) metal ions.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacteria; Cadmium; Cations, Divalent; Cell Division; Cell Line; Chelating Agents; Cricetinae; Crystallography, X-Ray; Drug Interactions; Humans; Ibuprofen; In Vitro Techniques; Indomethacin; Ligands; Models, Molecular; Platinum; Structure-Activity Relationship; Tolmetin; Tumor Cells, Cultured; Zinc | 1998 |
Cell-type-specific activation of c-Jun N-terminal kinase by salicylates.
Topics: Acetaminophen; Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcium-Calmodulin-Dependent Protein Kinases; Chlorocebus aethiops; Colonic Neoplasms; COS Cells; Cyclooxygenase Inhibitors; Enzyme Activation; Epidermal Growth Factor; Fibroblasts; Humans; Hypertonic Solutions; Ibuprofen; Indomethacin; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; NF-kappa B; Organ Specificity; Osmotic Pressure; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-jun; Recombinant Fusion Proteins; Saline Solution, Hypertonic; Signal Transduction; Sodium Salicylate; Sorbitol; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
Kinetic basis for selective inhibition of cyclo-oxygenases.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Ibuprofen; Indomethacin; Inhibitory Concentration 50; Isoenzymes; Kinetics; Male; Membrane Proteins; Mice; Naproxen; Oxygen; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sheep; Structure-Activity Relationship; Sulfonamides; Tetramethylphenylenediamine; Thermodynamics | 1999 |
Induction of stromelysin gene expression by tumor necrosis factor alpha is inhibited by dexamethasone, salicylate, and N-acetylcysteine in synovial fibroblasts.
Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Cattle; Cells, Cultured; Dexamethasone; Fibroblasts; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Ibuprofen; Indomethacin; Matrix Metalloproteinase 3; Proline; Sodium Salicylate; Synovial Membrane; Thiocarbamates; Tissue Inhibitor of Metalloproteinase-3; Transcription Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha; Vitamin E | 1999 |
Selective potentiation of drug cytotoxicity by NSAID in human glioma cells: the role of COX-1 and MRP.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; ATP-Binding Cassette Transporters; Cyclooxygenase 1; Cyclooxygenase 2; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Glioma; Humans; Ibuprofen; Indomethacin; Isoenzymes; Membrane Proteins; Multidrug Resistance-Associated Proteins; Prostaglandin-Endoperoxide Synthases; Tumor Cells, Cultured; Vincristine | 1999 |
Cytokines inhibit sexual behavior in female rats: II. Prostaglandins mediate the suppressive effects of interleukin-1beta.
Topics: Animals; Corticosterone; Cyclooxygenase Inhibitors; Cytokines; Depression, Chemical; Female; Hypothalamus; Ibuprofen; Indomethacin; Injections, Intraventricular; Interleukin-1; Male; Pentoxifylline; Posture; Prostaglandins; Rats; Rats, Inbred F344; Sexual Behavior, Animal; Vasodilator Agents | 1999 |
Mechanism of drug release from poly(L-lactic acid) matrix containing acidic or neutral drugs.
Topics: Biodegradation, Environmental; Crystallization; Delayed-Action Preparations; Diffusion; Griseofulvin; Hydrogen-Ion Concentration; Ibuprofen; Indomethacin; Lactic Acid; Naproxen; Polymers; Progesterone; Solubility; Testosterone | 1999 |
Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arachidonic Acid; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Embryo, Mammalian; Fibroblasts; Ibuprofen; Indomethacin; Isoenzymes; Membrane Proteins; Mice; Mice, Knockout; Nitrobenzenes; Oncogene Proteins, Viral; Piroxicam; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins p21(ras); RNA, Messenger; Simian virus 40; Sulfonamides; Sulindac | 1999 |
Effects of ibuprofen and indomethacin on the regional circulation in newborn piglets.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Blood Flow Velocity; Brain; Digestive System; Fluorescent Dyes; Ibuprofen; Indomethacin; Kidney; Kidney Cortex; Kidney Medulla; Microspheres; Swine; Vascular Resistance | 1999 |
Response to isoprenaline of rabbit detrusor muscle following exposure to 5, 8, 11, 14 eicosatetraynoic acid. Role of prostanoids on beta-adrenergic-evoked response.
Topics: Alprostadil; Animals; Arachidonic Acids; Cyclooxygenase Inhibitors; Dinoprostone; Drug Interactions; Evoked Potentials; Ibuprofen; In Vitro Techniques; Indomethacin; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Prostaglandins; Rabbits; Receptors, Adrenergic, beta; Time Factors | 1999 |
Inhibitors of prostaglandin synthesis do not improve food intake or body weight of tumor-bearing rats.
Topics: Analysis of Variance; Animals; Anorexia; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cachexia; Carcinoma, Hepatocellular; Circadian Rhythm; Eating; Ibuprofen; Indomethacin; Interleukin-1; Liver Neoplasms, Experimental; Male; Rats; Tumor Necrosis Factor-alpha | 1999 |
Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4).
Topics: Animals; Aspirin; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Activation; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Enzymologic; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indomethacin; Isoenzymes; Lipoxins; Liver; Male; Membrane Proteins; Phenobarbital; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; RNA, Messenger; Sulfonamides; Thromboxane B2 | 1999 |
Back to the drawing board.
Topics: Brain; Ductus Arteriosus, Patent; Echocardiography; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Randomized Controlled Trials as Topic; Regional Blood Flow | 2000 |
Cyclooxygenase-independent inhibition of smooth muscle cell mitogenesis by ibuprofen.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Becaplermin; Cattle; Cell Division; Cells, Cultured; Cyclooxygenase Inhibitors; DNA; Dose-Response Relationship, Drug; Ibuprofen; Indomethacin; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Stereoisomerism | 2000 |
Human mast cells take up and hydrolyze anandamide under the control of 5-lipoxygenase and do not express cannabinoid receptors.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Amides; Arachidonate 5-Lipoxygenase; Arachidonic Acids; Binding, Competitive; Biological Transport; Cannabinoids; Cell Line; Cyclooxygenase Inhibitors; Endocannabinoids; Ethanolamines; Humans; Ibuprofen; Indoles; Indomethacin; Kinetics; Lipoxygenase Inhibitors; Mast Cells; Palmitic Acids; Polyunsaturated Alkamides; Receptors, Cannabinoid; Receptors, Drug; Tritium | 2000 |
Aspirin and some other nonsteroidal anti-inflammatory drugs inhibit cystic fibrosis transmembrane conductance regulator protein gene expression in T-84 cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Anions; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line; Cell Survival; Chlorides; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Inhibitors; Gene Expression Regulation; Humans; Ibuprofen; Indomethacin; Recombinant Proteins; RNA, Messenger; Thionucleotides; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1999 |
Antinociceptive and anti-oedematogenic properties of astilbin, taxifolin and some related compounds.
Topics: Acetaminophen; Acetates; Analgesics; Analgesics, Non-Narcotic; Animals; Aspirin; Edema; Flavonoids; Flavonols; Formaldehyde; Ibuprofen; Indomethacin; Male; Mice; Pain Measurement; Quercetin; Rats; Rats, Wistar | 2000 |
Uptake of ibuprofen, indomethacin and ketoprofen into isolated rabbit parietal cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cold Temperature; Hydrogen-Ion Concentration; Ibuprofen; Indomethacin; Ketoprofen; Male; Parietal Cells, Gastric; Rabbits | 2000 |
Ibuprofen as effective as indomethacin for patent ductus arteriosus.
Topics: Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Oliguria | 2000 |
Ibuprofen and patent ductus arteriosus.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases | 2000 |
Differences in the pharmacological properties of rat and chicken brain fatty acid amidohydrolase.
Topics: Amidohydrolases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Brain; Chickens; Diazomethane; Enzyme Inhibitors; Ibuprofen; In Vitro Techniques; Indomethacin; Phenylmethylsulfonyl Fluoride; Rats; Rats, Sprague-Dawley; Species Specificity | 2000 |
Inhibition of inducible nitric oxide synthase gene expression by indomethacin or ibuprofen in beta-amyloid protein-stimulated J774 cells.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antineoplastic Agents; Cell Line; Cyclooxygenase Inhibitors; Gene Expression Regulation, Enzymologic; Ibuprofen; Indomethacin; Interferon-gamma; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; RNA, Messenger | 2000 |
Mechanical stretch reveals different components of endothelial-mediated vascular tone in rat aortic strips.
Topics: Acetylcholine; Aminoquinolines; Animals; Aorta, Thoracic; Cyclooxygenase Inhibitors; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Fatty Acids, Unsaturated; Guanylate Cyclase; Ibuprofen; In Vitro Techniques; Indoles; Indomethacin; Lipoxygenase Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Wistar; Stress, Mechanical; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Don't discard your indomethacin yet.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Birth Weight; Brain; Cerebral Hemorrhage; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Gestational Age; Humans; Ibuprofen; Incidence; Indomethacin; Infant, Newborn; Infant, Premature; Injections, Intravenous; Kidney; Ligation | 2000 |
Prostaglandin H synthase-2 inhibitors interfere with prostaglandin H synthase-1 inhibition by nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Cattle; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Ibuprofen; Indomethacin; Isoenzymes; Male; Microsomes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sulfonamides; Thiophenes | 2001 |
Ibuprofen versus indomethacin for closure of patent ductus arteriosus.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Recurrence | 2001 |
The involvement of phospholipase A(2) in ethanol-induced gastric muscle contraction.
Topics: Animals; Cats; Central Nervous System Depressants; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ethanol; Female; Gastric Fundus; Ibuprofen; Indomethacin; Inositol Phosphates; Male; Muscle Contraction; Muscle, Smooth; Phosphodiesterase Inhibitors; Phospholipases A; Phosphorylcholine; Terpenes | 2001 |
Agonist-specific regulation of monocyte chemoattractant protein-1 expression by cyclooxygenase metabolites in hepatic stellate cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cells, Cultured; Chemokine CCL2; Cyclic AMP; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Gene Expression; Humans; Ibuprofen; Indomethacin; Interleukin-1; Isoenzymes; Liver; Membrane Proteins; NF-kappa B; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2001 |
Determination of nonsteroidal anti-inflammatory drugs in biological fluids by automatic on-line integration of solid-phase extraction and capillary electrophoresis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Automation; Chromatography, Micellar Electrokinetic Capillary; Humans; Ibuprofen; Indomethacin; Ketoprofen; Phenylbutyrates; Tolmetin | 2001 |
In vitro effect of different non-steroidal anti-inflammatory drugs on human polymorphonuclear leukocyte activity measured by luminol-dependent chemiluminescence of the whole blood.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Barium Sulfate; Blood Group Antigens; Contrast Media; Diclofenac; Drug Evaluation, Preclinical; Erythrocyte Indices; Female; Hemoglobins; Humans; Ibuprofen; Indicators and Reagents; Indomethacin; Leukocyte Count; Luminescent Measurements; Luminol; Male; Middle Aged; Neutrophils | 2001 |
Mechanism of acetaminophen inhibition of cyclooxygenase isoforms.
Topics: Acetaminophen; Animals; Binding, Competitive; Cyclooxygenase 1; Cyclooxygenase 2; Enzyme Activation; Glutathione; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Ibuprofen; Indomethacin; Isoenzymes; Linoleic Acids; Lipid Peroxides; Membrane Proteins; Oxidation-Reduction; Prostaglandin-Endoperoxide Synthases; Reducing Agents; Sheep | 2001 |
Simulated microgravity upregulates an endothelial vasoconstrictor prostaglandin.
Topics: Analysis of Variance; Animals; Bridged Bicyclo Compounds, Heterocyclic; Carotid Arteries; Cyclooxygenase Inhibitors; Endothelium, Vascular; Fatty Acids, Unsaturated; Hindlimb Suspension; Hydrazines; Ibuprofen; In Vitro Techniques; Indomethacin; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Norepinephrine; Rats; Rats, Wistar; Receptors, Thromboxane; Time Factors; Vasoconstriction; Weightlessness Simulation | 2001 |
Nonsteroidal anti-inflammatory drugs for perioperative pain control.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Etodolac; Humans; Ibuprofen; Indomethacin; Ketorolac; Lactones; Nabumetone; Naproxen; Pain, Postoperative; Piroxicam; Pyrazoles; Sulfonamides; Sulfones; Time Factors | 2001 |
A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid Endopeptidases; Brain; CHO Cells; Cricetinae; Disease Models, Animal; Endopeptidases; Enzyme-Linked Immunosorbent Assay; Humans; Ibuprofen; Indomethacin; Mass Spectrometry; Mice; Mice, Transgenic; Peptide Fragments; Prostaglandin-Endoperoxide Synthases; Sulindac; Tumor Cells, Cultured | 2001 |
Tumor necrosis factor-alpha induces the expression of DR6, a member of the TNF receptor family, through activation of NF-kappaB.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; bcl-X Protein; Chromosome Mapping; Chromosomes, Human, Pair 6; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; I-kappa B Proteins; Ibuprofen; Indomethacin; Male; NF-kappa B; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Up-Regulation | 2001 |
Activation of peroxisome proliferator-activated receptor isoforms and inhibition of prostaglandin H(2) synthases by ibuprofen, naproxen, and indomethacin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Ibuprofen; Indomethacin; Naproxen; Prostaglandin-Endoperoxide Synthases; Protein Isoforms; Rats; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Tumor Cells, Cultured | 2001 |
Non-steroidal anti-inflammatory drugs inhibit telomerase activity in head and neck squamous carcinoma cell lines.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Cycle; Cell Division; Head and Neck Neoplasms; Humans; Hydrocortisone; Ibuprofen; Indomethacin; Keratinocytes; Telomerase; Tumor Cells, Cultured | 2001 |
A study of the conditions of the supercritical fluid extraction in the analysis of selected anti-inflammatory drugs in plasma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Carbon Dioxide; Chromatography, High Pressure Liquid; Chromatography, Supercritical Fluid; Flufenamic Acid; Ibuprofen; Indomethacin; Methanol; Methylene Chloride; Solvents | 2002 |
Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of gamma-glutamylcysteine synthetase.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blotting, Northern; Carcinoma, Hepatocellular; Carrier Proteins; Chloramphenicol O-Acetyltransferase; DNA-Binding Proteins; Fluorescent Antibody Technique, Indirect; Glutamate-Cysteine Ligase; Glutathione; Humans; Ibuprofen; Indomethacin; Leucine Zippers; Liver Neoplasms; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; NF-E2-Related Factor 2; Oxidation-Reduction; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; RNA, Messenger; Trans-Activators; Transfection; Tumor Cells, Cultured | 2002 |
Comparison of vasoconstrictor responses to selected NSAIDs in rabbit renal and femoral arteries.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Femoral Artery; Ibuprofen; In Vitro Techniques; Indomethacin; Phenacetin; Rabbits; Renal Artery; Vasoconstriction | 2002 |
Non-steroidal anti-inflammatory drugs stimulate secretion of non-amyloidogenic precursor protein.
Topics: Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Enzyme Activation; Humans; Ibuprofen; Indomethacin; Kinetics; Mitogen-Activated Protein Kinases; Neuroblastoma; PC12 Cells; Pheochromocytoma; Rats; Sulfonamides; Thalidomide; Tumor Cells, Cultured | 2002 |
Effect of inflammatory mediators on the physiology of the human Fallopian tube.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Diclofenac; Dose-Response Relationship, Drug; Electric Conductivity; Electrophysiology; Epithelial Cells; Fallopian Tubes; Female; Histamine; Humans; Ibuprofen; Indomethacin; Inflammation Mediators; Muscle Contraction; Muscle, Smooth; Naproxen; Pelvic Pain; Platelet Activating Factor | 2002 |
Assessment of spinal cord pathology following trauma using early changes in the spinal cord evoked potentials: a pharmacological and morphological study in the rat.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Coloring Agents; Cyproheptadine; Dexamethasone; Edema; Electrophysiology; Endothelium; Evans Blue; Evoked Potentials; Fenclonine; Ibuprofen; Indomethacin; Male; Nimodipine; Phentolamine; Propranolol; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Spinal Cord; Spinal Cord Injuries | 2002 |
Indomethacin and ibuprofen effect on IL-1ra production by mononuclear cells of preterm newborns and adults.
Topics: Adult; Aging; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Interleukin 1 Receptor Antagonist Protein; Middle Aged; Monocytes; Sialoglycoproteins | 2002 |
On the interaction of specific prostaglandin H synthase-2 inhibitors with prostaglandin H synthase-1.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Binding, Competitive; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ibuprofen; In Vitro Techniques; Indomethacin; Isoenzymes; Male; Microsomes; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Sheep; Sulfonamides | 2002 |
Study of the mechanisms involved in the bradykinin-induced contraction of the pig iris sphincter muscle in vitro.
Topics: Animals; Atropine; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanethidine; Ibuprofen; Imidazoles; In Vitro Techniques; Indomethacin; Iris; Kallidin; Muscle Contraction; Muscle, Smooth; Nitrobenzenes; Propionates; Quinolines; Salicylates; Sulfonamides; Swine; Tetrodotoxin; Thromboxane-A Synthase | 2003 |
The adverse renal effects of prostaglandin-synthesis inhibitors in the newborn rabbit.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Pressure; Cyclooxygenase Inhibitors; Disease Models, Animal; Glomerular Filtration Rate; Heart Rate; Ibuprofen; Indomethacin; Inulin; Kidney; Kidney Diseases; p-Aminohippuric Acid; Rabbits | 2002 |
Safety and efficacy of ibuprofen versus indomethacin in preterm infants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Research Design; Safety | 2003 |
Characterization of the thermal properties of powder particles using microthermal analysis.
Topics: Albuterol; Calorimetry, Differential Scanning; Caprolactam; Chemical Phenomena; Chemistry, Physical; Drug Stability; Heating; Ibuprofen; Indomethacin; Polymers; Powders; Trehalose | 2003 |
Ibuprofen for closure of patent ductus arteriosus: is it really safe in hyperbilirubinaemic infants?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Humans; Hyperbilirubinemia; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature | 2003 |
Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit vascular smooth muscle cell proliferation via differential effects on the cell cycle.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Aspirin; Cell Division; Cell Line; Diclofenac; Dose-Response Relationship, Drug; Flow Cytometry; Ibuprofen; Indomethacin; Muscle, Smooth, Vascular; Rats; Sodium Salicylate; Sulindac | 2003 |
[Gastrointestinal hemorrhages as complications of gastropathies associated with intake of nonsteroidal anti-inflammatory drugs].
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Duodenal Ulcer; Duodenoscopy; Esophageal Diseases; Esophagoscopy; Female; Gastric Mucosa; Gastroscopy; Humans; Ibuprofen; Indomethacin; Male; Peptic Ulcer Hemorrhage; Retrospective Studies; Stomach Ulcer | 2003 |
Effect of selective vs. non-selective cyclo-oxygenase inhibitors on fetal membrane prostaglandin synthesis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Extraembryonic Membranes; Female; Furans; Humans; Ibuprofen; Indomethacin; Inhibitory Concentration 50; Isoenzymes; Meloxicam; Membrane Proteins; Pregnancy; Prostaglandin-Endoperoxide Synthases; Sulfonamides; Thiazines; Thiazoles | 2003 |
Application of dense gas techniques for the production of fine particles.
Topics: Aerosols; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Gases; Ibuprofen; Indomethacin; Particle Size; Powders; Solubility | 2003 |
Antinociceptive synergy, additivity, and subadditivity with combinations of oral glucosamine plus nonopioid analgesics in mice.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Disease Models, Animal; Drug Therapy, Combination; Glucosamine; Ibuprofen; Indomethacin; Ketoprofen; Mice; Pain; Piroxicam | 2003 |
A rapid and simultaneous determination of several analgesic antiinflammatory agents by capillary zone electrophoresis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Fluorescence Polarization Immunoassay; Humans; Ibuprofen; Indomethacin; Salicylic Acid | 2003 |
Indomethacin and ibuprofen induce Hsc70 nuclear localization and activation of the heat shock response in HeLa cells.
Topics: Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents, Non-Steroidal; DNA; DNA-Binding Proteins; Heat Shock Transcription Factors; Heat-Shock Response; HeLa Cells; HSC70 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Ibuprofen; Indomethacin; MAP Kinase Signaling System; Mice; Models, Biological; NIH 3T3 Cells; Oxidative Stress; Transcription Factors | 2004 |
Loss prevention case of the month. Monitoring remains critical.
Topics: Acetaminophen; Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Clinical Competence; Diagnostic Errors; Doxepin; Drug Monitoring; Fatal Outcome; Female; Humans; Hydrocodone; Ibuprofen; Indomethacin; Middle Aged; Sulfasalazine; Time Factors; Trimethoprim, Sulfamethoxazole Drug Combination | 2004 |
Postpartum hypertension and nonsteroidal analgesia.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Hypertension; Ibuprofen; Indomethacin; Puerperal Disorders | 2004 |
Pharmacological modulation of TNF production in macrophages.
Topics: Animals; Benzoquinones; Cell Line; Cyclooxygenase Inhibitors; Ibuprofen; Indomethacin; Lipopolysaccharides; Lipoxygenase Inhibitors; Macrophage Activation; Macrophages; Mice; Pentoxifylline; Tumor Necrosis Factor-alpha | 2004 |
Endoplasmic reticulum stress response is involved in nonsteroidal anti-inflammatory drug-induced apoptosis.
Topics: Activating Transcription Factor 4; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blotting, Northern; Celecoxib; Cell Line; Cell Survival; Cells, Cultured; Diclofenac; DNA-Binding Proteins; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme Activation; Gastric Mucosa; Genes, Reporter; Guinea Pigs; Heat-Shock Proteins; Hydrogen Peroxide; Ibuprofen; Immunoblotting; Indomethacin; Luciferases; Macrophages; Microscopy, Fluorescence; Molecular Chaperones; Plasmids; Pyrazoles; Regulatory Factor X Transcription Factors; RNA, Messenger; Sulfonamides; Time Factors; Transcription Factors; Transcription, Genetic; Transfection; X-Box Binding Protein 1 | 2004 |
Indomethacin and ibuprofen preserve gastrocnemius muscle mass in mice bearing the colon-26 adenocarcinoma.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cachexia; Colonic Neoplasms; Disease Models, Animal; Female; Ibuprofen; Indomethacin; Mice; Muscle, Skeletal; Neoplasms, Experimental; Ubiquinone | 2004 |
Cellular mechanisms of acetaminophen: role of cyclo-oxygenase.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Cell Line; Cyclooxygenase Inhibitors; Diclofenac; Enzyme Activation; Humans; Ibuprofen; Indomethacin; Lactones; Lung; Naproxen; Oxidation-Reduction; Prostaglandin-Endoperoxide Synthases; Protein Biosynthesis; Sulfones; tert-Butylhydroperoxide; Transcription, Genetic | 2005 |
Efficacy and renal tolerability of ibuprofen vs. indomethacin in preterm infants with patent ductus arteriosus.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Male; Maternal Age; Retrospective Studies | 2005 |
Selective inhibitors differentially affect cyclooxygenase-dependent pial arteriolar responses in newborn pigs.
Topics: Acetaminophen; Animals; Animals, Newborn; Arterioles; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Hypercapnia; Hypotension; Ibuprofen; Indomethacin; Male; Methacholine Chloride; Nitrobenzenes; Pia Mater; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Swine; Vasoconstriction; Vasodilation | 2005 |
Gastric and thymic assay of acute oral treatment of rats with nitric oxide esters of ibuprofen or indomethacin.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Esterification; Gastric Mucosa; Ibuprofen; Indomethacin; Male; Nitric Oxide; Peptic Ulcer; Rats; Rats, Wistar; Stomach; Thymus Gland | 2005 |
Urinary ET-1, AVP and sodium in premature infants treated with indomethacin and ibuprofen for patent ductus arteriosus.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arginine Vasopressin; Cyclooxygenase 2 Inhibitors; Ductus Arteriosus, Patent; Endothelin-1; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Sodium | 2005 |
Induction of HSP70 expression and recruitment of HSC70 and HSP70 in the nucleus reduce aggregation of a polyalanine expansion mutant of PABPN1 in HeLa cells.
Topics: Active Transport, Cell Nucleus; Cell Nucleus; Green Fluorescent Proteins; HeLa Cells; HSC70 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Ibuprofen; Indomethacin; Intranuclear Inclusion Bodies; Muscular Dystrophy, Oculopharyngeal; Mutation; Octoxynol; Oxyquinoline; Peptides; Poly(A)-Binding Protein I; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Solubility; Transfection; Up-Regulation; Zinc Sulfate | 2005 |
Eicosanoid-mediated proinflammatory activity of Pseudomonas aeruginosa ExoU.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Bacterial Proteins; Bacterial Toxins; Cell Line; Dinoprostone; Eicosanoids; Endothelial Cells; Epoprostenol; Female; Group IV Phospholipases A2; Humans; Ibuprofen; Indomethacin; Inflammation; Lipoxygenase Inhibitors; Masoprocol; Mice; Mice, Inbred BALB C; Organophosphonates; Phospholipases A; Pseudomonas aeruginosa; Pseudomonas Infections | 2005 |
Consequences of delayed surgical closure of patent ductus arteriosus in very premature infants.
Topics: Combined Modality Therapy; Ductus Arteriosus, Patent; Enteral Nutrition; Female; Gestational Age; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Male; Postoperative Complications; Retrospective Studies; Time Factors; Treatment Outcome; Weight Gain | 2006 |
NSAID-induced acute phase response is due to increased intestinal permeability and characterized by early and consistent alterations in hepatic gene expression.
Topics: Acute-Phase Reaction; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemokine CCL2; Chemokines, CXC; Cyclooxygenase 2 Inhibitors; Databases, Factual; Dose-Response Relationship, Drug; Gene Expression; Ibuprofen; Indomethacin; Intestinal Mucosa; Intestines; Lactones; Lipopolysaccharides; Liver; Male; Permeability; Rats; Rats, Sprague-Dawley; Sulfones; Time Factors | 2006 |
Brain uptake of nonsteroidal anti-inflammatory drugs: ibuprofen, flurbiprofen, and indomethacin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Biological Transport; Blood-Brain Barrier; Brain; Capillary Permeability; Flurbiprofen; Ibuprofen; Indomethacin; Kinetics; Male; Perfusion; Protein Binding; Rats; Rats, Wistar; Serum Albumin, Bovine | 2006 |
Comparative effects of early postnatal ibuprofen and indomethacin on VEGF, IGF-I, and GH during rat ocular development.
Topics: Animals; Animals, Newborn; Cyclooxygenase Inhibitors; Eye; Female; Growth Hormone; Ibuprofen; Indomethacin; Injections, Intraperitoneal; Insulin-Like Growth Factor I; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Vascular Endothelial Growth Factor; Retina; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vascular Endothelial Growth Factor A; Vitreous Body | 2006 |
Evaluation of the role of the arachidonic acid cascade in anandamide's in vivo effects in mice.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cannabinoid Receptor Modulators; Endocannabinoids; Ibuprofen; Indomethacin; Male; Mice; Mice, Inbred ICR; Phenylmethylsulfonyl Fluoride; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rimonabant | 2006 |
Intestinal effects of nonselective and selective cyclooxygenase inhibitors in the rat.
Topics: Administration, Oral; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enterobacteriaceae; Ibuprofen; Indomethacin; Intestinal Mucosa; Intestine, Small; Lipid Peroxidation; Male; Mucins; Peroxidase; Pyrazoles; Rats; Rats, Wistar; Sulfonamides | 2006 |
Primary and secondary red ear syndrome: implications for treatment.
Topics: Aged; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Ear Diseases; Erythema; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Ibuprofen; Indomethacin; Middle Aged; Temporomandibular Joint Disorders; Trigeminal Autonomic Cephalalgias | 2007 |
Design of original bioactive formulations based on sugar-surfactant/non-steroidal anti-inflammatory catanionic self-assemblies: a new way of dermal drug delivery.
Topics: Administration, Topical; Animals; Anions; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cations; Drug Carriers; Drug Delivery Systems; Drug Design; Ear; Edema; Ibuprofen; Indomethacin; Ketoprofen; Male; Mice; Permeability; Pharmaceutical Preparations; Skin Absorption; Surface-Active Agents; Swine | 2007 |
Inhibition of fatty acid amide hydrolase, a key endocannabinoid metabolizing enzyme, by analogues of ibuprofen and indomethacin.
Topics: Amidohydrolases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Brain; Cannabinoid Receptor Modulators; Cyclooxygenase Inhibitors; Endocannabinoids; Enzyme Inhibitors; Hydrogen-Ion Concentration; Hydrolysis; Ibuprofen; Indomethacin; Mice; Mice, Inbred BALB C; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Rats, Wistar | 2007 |
A potential anti-implantation and spermicidal strategy: putative derivatives of nonoxynol-9 and anti-inflammatory agents and their spermicidal activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Dose-Response Relationship, Drug; Drug Therapy, Combination; Ibuprofen; Indomethacin; Male; Nonoxynol; Sperm Motility; Spermatocidal Agents; Spermatozoa; Swine | 2006 |
Determination of degradation pathways and kinetics of acyl glucuronides by NMR spectroscopy.
Topics: Acylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile; Chromatography, Liquid; Cyclooxygenase Inhibitors; Diclofenac; Drug Stability; Flufenamic Acid; Glucuronides; Half-Life; Ibuprofen; Indomethacin; Kinetics; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mefenamic Acid; Molecular Structure; Rats; Rats, Sprague-Dawley; Stereoisomerism; Technology, Pharmaceutical; Tolmetin | 2007 |
The development of heated tip force-distance measurements as a novel approach to site-specific characterization of pharmaceutical materials.
Topics: Acetaminophen; Adhesives; Calibration; Hot Temperature; Ibuprofen; Indomethacin; Microscopy, Atomic Force; Pharmaceutical Preparations; Reproducibility of Results; Sensitivity and Specificity; Surface Properties; Tablets; Technology, Pharmaceutical; Thermodynamics | 2008 |
Oral ibuprofen in early curative closure of patent ductus arteriosus in very premature infants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Echocardiography, Doppler, Color; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infusions, Intravenous; Male; Treatment Outcome | 2007 |
Renal glomeruli and tubular injury following indomethacin, ibuprofen, and gentamicin exposure in a neonatal rat model.
Topics: Analgesics, Non-Narcotic; Animals; Animals, Newborn; Anti-Bacterial Agents; Cardiovascular Agents; Female; Gentamicins; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Kidney Glomerulus; Kidney Tubules; Pregnancy; Rats; Rats, Sprague-Dawley | 2007 |
The anti-inflammatory mechanism of 635 nm light-emitting-diode irradiation compared with existing COX inhibitors.
Topics: Adult; Biomarkers; Blotting, Western; Cyclooxygenase Inhibitors; Dinoprostone; Fibroblasts; Flow Cytometry; Gingival Diseases; Humans; Ibuprofen; Indomethacin; Microscopy, Confocal; Oxidative Stress; Phototherapy; Prostaglandin-Endoperoxide Synthases; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA; Wound Healing | 2007 |
Early postnatal ibuprofen and indomethacin effects in suckling and weanling rat kidneys.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Animals, Newborn; Animals, Suckling; Cyclooxygenase 2; Dinoprost; Dinoprostone; Ductus Arteriosus, Patent; Ibuprofen; Indomethacin; Kidney; Prostaglandins; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Thromboxane B2 | 2008 |
Growth compensatory role of sulindac sulfide-induced thrombospondin-1 linked with ERK1/2 and RhoA GTPase signaling pathways.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulation; Humans; Ibuprofen; Indomethacin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; rhoA GTP-Binding Protein; Signal Transduction; Sulindac; Thrombospondin 1 | 2008 |
Induction of expression and co-localization of heat shock polypeptides with the polyalanine expansion mutant of poly(A)-binding protein N1 after chemical stress.
Topics: Cell Nucleus; Green Fluorescent Proteins; Heat-Shock Proteins; HeLa Cells; HSP110 Heat-Shock Proteins; HSP27 Heat-Shock Proteins; HSP40 Heat-Shock Proteins; Humans; Ibuprofen; Indomethacin; Molecular Chaperones; Mutation; Neoplasm Proteins; Oxyquinoline; Peptides; Poly(A)-Binding Protein II; Transfection; Zinc Sulfate | 2008 |
Nonsteroidal anti-inflammatory drugs and ectodomain shedding of the amyloid precursor protein.
Topics: Alkaline Phosphatase; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Ibuprofen; Indomethacin; Kinetics; Neuroblastoma; PC12 Cells; Rats; Tetradecanoylphorbol Acetate | 2009 |
Membrane fusion: a new function of non steroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Dimyristoylphosphatidylcholine; Ibuprofen; Indomethacin; Meloxicam; Membrane Fusion; Piroxicam; Propionates; Thiazines; Thiazoles | 2008 |
Total serum bilirubin levels during cyclooxygenase inhibitor treatment for patent ductus arteriosus in preterm infants.
Topics: Bilirubin; Child, Preschool; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Hemodynamics; Humans; Hyperbilirubinemia; Ibuprofen; Indomethacin; Infant; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Male; Retrospective Studies | 2009 |
Suppression of cytokine responses by indomethacin in podocytes: a mechanism through induction of unfolded protein response.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Northern; Blotting, Western; Cell Line; Cells, Cultured; Chemokine CCL2; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Escherichia coli Proteins; Gene Expression; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Ibuprofen; Indomethacin; Mice; Models, Biological; Molecular Chaperones; NF-kappa B; Podocytes; PPAR gamma; Protein Folding; Proteins; Subtilisins; Thapsigargin; TNF Receptor-Associated Factor 2; Transcription Factor CHOP; Tumor Necrosis Factor-alpha | 2008 |
Removal of selected pharmaceuticals by chlorination, coagulation-sedimentation and powdered activated carbon treatment.
Topics: Antipyrine; Charcoal; Clofibric Acid; Diclofenac; Fenoprofen; Gemfibrozil; Halogenation; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Water Pollutants, Chemical; Water Purification; Water Supply | 2008 |
Estimation of drug solubility in polymers via differential scanning calorimetry and utilization of the fox equation.
Topics: Algorithms; Calorimetry, Differential Scanning; Chromatography, High Pressure Liquid; Complex Mixtures; Crystallization; Glass; Ibuprofen; Indomethacin; Molecular Structure; Naproxen; Pharmaceutical Preparations; Polyethylene Glycols; Polymers; Solubility; Thermography; Transition Temperature | 2009 |
The influence of the preparation methods on the inclusion of model drugs in a beta-cyclodextrin cavity.
Topics: Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Chemistry, Pharmaceutical; Drug Carriers; Freeze Drying; Hydrogen-Ion Concentration; Ibuprofen; Indomethacin; Powders; Solubility | 2009 |
[First SIBEN clinical consensus: diagnostic and therapeutic approach to patent ductus arteriosus in premature newborns].
Topics: Age Factors; Brain Diseases; Cost-Benefit Analysis; Cyclooxygenase Inhibitors; Diuretics; Ductus Arteriosus, Patent; Enteral Nutrition; Fluid Therapy; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Ultrasonography; Water-Electrolyte Balance | 2008 |
Delayed neonatal closure of the ductus arteriosus following early in utero exposure to indomethacin in the rat.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Fetus; Gestational Age; Ibuprofen; Indomethacin; Male; Maternal Exposure; Pregnancy; Pyrazoles; Rats; Rats, Wistar | 2009 |
Indomethacin, ibuprofen and gentamicin administered during late stages of glomerulogenesis do not reduce glomerular number at 14 days of age in the neonatal rat.
Topics: Analgesics, Non-Narcotic; Animals; Animals, Newborn; Anti-Bacterial Agents; Body Weight; Cardiovascular Agents; Drug Combinations; Female; Gentamicins; Ibuprofen; Indomethacin; Kidney Glomerulus; Nephrons; Organ Size; Pregnancy; Rats; Rats, Sprague-Dawley | 2009 |
Potential for control of detrusor smooth muscle spontaneous rhythmic contraction by cyclooxygenase products released by interstitial cells of Cajal.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Female; Hydrazines; Ibuprofen; Indomethacin; Interstitial Cells of Cajal; Muscle Contraction; Muscle, Smooth; Oxazepines; Prostaglandins; Rabbits; Urinary Bladder; Vimentin | 2009 |
Pattern recognition analysis for the prediction of adverse effects by nonsteroidal anti-inflammatory drugs using 1H NMR-based metabolomics in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Ibuprofen; Indomethacin; Least-Squares Analysis; Magnetic Resonance Spectroscopy; Male; Metabolomics; Pattern Recognition, Automated; Predictive Value of Tests; Pyrazoles; Rats; Rats, Sprague-Dawley; Stomach; Sulfonamides | 2009 |
Effects of non-steroidal anti-inflammatory drugs on Abeta deposition in Abeta(1-42) transgenic C. elegans.
Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Animals, Genetically Modified; Anti-Inflammatory Agents, Non-Steroidal; Benzothiazoles; Caenorhabditis elegans; Diclofenac; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Ibuprofen; Indomethacin; Microscopy, Confocal; Thiazoles | 2009 |
Hormonal influences of early postnatal indomethacin and ibuprofen in neonatal rats.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Carrier Proteins; Corticosterone; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Growth Hormone; Ibuprofen; Indomethacin; Insulin; Insulin-Like Growth Factor I; Prostaglandins; Rats; Rats, Sprague-Dawley | 2010 |
[Patent ductus arteriosus in premature infants].
Topics: Bronchopulmonary Dysplasia; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Hemodynamics; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Postoperative Complications; Risk Factors | 2009 |
The impact of ibuprofen or indomethacin on renal drug clearance in neonates.
Topics: Amikacin; Anti-Bacterial Agents; Cyclooxygenase Inhibitors; Drug Interactions; Glomerular Filtration Rate; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Kidney; Metabolic Clearance Rate; Vancomycin | 2009 |
Effects of treatments on inflammatory and apoptotic markers in the CNS of mice with globoid cell leukodystrophy.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD; Apoptosis; Biomarkers; Bone Marrow Transplantation; Cell Count; Cerebellum; Cerebral Cortex; Chemokines; Cytokines; Galactosylceramidase; Ibuprofen; In Situ Nick-End Labeling; Indomethacin; Inflammation; Leukodystrophy, Globoid Cell; Mice; Mice, Transgenic; Minocycline; Neurons; Nitric Oxide Synthase Type II; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord | 2009 |
N-terminal-pro-B-type natriuretic peptide in premature patent ductus arteriosus: a physiologic biomarker, but is it a clinical tool?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Drug Monitoring; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infusions, Intravenous; Natriuretic Peptide, Brain; Peptide Fragments; Pilot Projects; Randomized Controlled Trials as Topic; Sensitivity and Specificity | 2010 |
Treatment of patent ductus arteriosus: indomethacin or ibuprofen?
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Male; Premature Birth; Retrospective Studies; Treatment Outcome | 2010 |
Safety and effectiveness of indomethacin versus ibuprofen for treatment of patent ductus arteriosus.
Topics: Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Male; Retrospective Studies; Treatment Outcome | 2010 |
Anti-inflammatory drugs selectively target sporangium development in Mucor.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Aspirin; Benzoic Acid; Ibuprofen; Indomethacin; Mitochondria; Mortierella; Mucor; Mucormycosis; Plant Diseases; Salicylic Acid | 2009 |
Neurodevelopmental outcome after COX inhibitor treatment for patent ductus arteriosus.
Topics: Central Nervous System; Child Development; Child, Preschool; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Gestational Age; Humans; Ibuprofen; Indomethacin; Infant; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Male; Psychomotor Performance; Retrospective Studies | 2010 |
Cyclooxygenase-derived mediators regulate the immunological control of Strongyloides venezuelensis infection.
Topics: Animals; Ascitic Fluid; Blood; Bronchoalveolar Lavage Fluid; Celecoxib; Dinoprostone; Duodenum; Enzyme Inhibitors; Eosinophils; Ibuprofen; Indomethacin; Leukocytes, Mononuclear; Lung; Male; Mice; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Wistar; Strongyloides; Strongyloidiasis; Sulfonamides; Th1 Cells; Th2 Cells | 2010 |
Episodic cluster headache: a rare diagnosis in children.
Topics: Acetaminophen; Age of Onset; Child; Cluster Headache; Diagnosis, Differential; Female; Humans; Ibuprofen; Indomethacin; Oxygen | 2010 |
A new open tubular capillary microextraction and sweeping for the analysis of super low concentration of hydrophobic compounds.
Topics: Animals; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Indomethacin; Loratadine; Rabbits; Solid Phase Microextraction; Temperature | 2010 |
Cyclooxygenase-independent mechanism of ibuprofen-induced antipyresis: the role of central vasopressin V₁ receptors.
Topics: Animals; Antipyretics; Arginine Vasopressin; Dinoprostone; Dose-Response Relationship, Drug; Fever; Ibuprofen; Indomethacin; Injections, Intraperitoneal; Injections, Intraventricular; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Male; Rats; Rats, Wistar; Receptors, Vasopressin | 2011 |
Urinary aquaporin-2 excretion during ibuprofen or indomethacin treatment in preterm infants with patent ductus arteriosus.
Topics: Aquaporin 2; Cardiovascular Agents; Ductus Arteriosus, Patent; Female; Gestational Age; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Osmolar Concentration | 2011 |
Patent ductus arteriosus in the preterm infant: a survey of clinical practices in French neonatal intensive care units.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Contraindications; Data Collection; Dose-Response Relationship, Drug; Drug Administration Schedule; Ductus Arteriosus, Patent; Echocardiography; France; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Intensive Care Units, Neonatal; Ligation; Recurrence; Retreatment; Surveys and Questionnaires | 2011 |
Treatment of patent ductus arteriosus with bidirectional flow in neonates.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Ductus Arteriosus, Patent; Echocardiography; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Male; Survival Analysis | 2011 |
The effects of NSAIDs on types I, II, and III collagen metabolism in a rat osteoarthritis model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Celecoxib; Chondrocytes; Collagen Type I; Collagen Type II; Collagen Type III; Disease Models, Animal; Ibuprofen; Immunohistochemistry; Indomethacin; Osteoarthritis; Proteoglycans; Pyrazoles; Rats; Rats, Wistar; Sulfonamides; Time Factors | 2012 |
Protective effects of antioxidants and anti-inflammatory agents against manganese-induced oxidative damage and neuronal injury.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Antioxidants; Cells, Cultured; Cerebrum; Chromans; Dinoprostone; F2-Isoprostanes; Female; Ibuprofen; Indomethacin; Manganese Poisoning; Mice; Mice, Inbred C57BL; Neurons; Neurotoxicity Syndromes; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2011 |
Comparison of renal effects of ibuprofen versus indomethacin during treatment of patent ductus arteriosus in contiguous historical cohorts.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Creatinine; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Kidney; Male; Prospective Studies | 2011 |
RhoA-inhibiting NSAIDs promote axonal myelination after spinal cord injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Axons; Cells, Cultured; Female; Ibuprofen; Indomethacin; Myelin Sheath; Nerve Fibers, Myelinated; Nerve Regeneration; Rats; Rats, Sprague-Dawley; Recovery of Function; rhoA GTP-Binding Protein; Spinal Cord; Spinal Cord Injuries | 2011 |
Update on management of patent ductus arteriosus in the preterm infant.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases | 2011 |
Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Line, Tumor; Cell Survival; Drug Interactions; Drug Therapy, Combination; Enzyme Inhibitors; Female; HEK293 Cells; Humans; Hydrolysis; Ibuprofen; Indomethacin; Inhibitory Concentration 50; Kinetics; Mice; Mice, Inbred BALB C; Mice, Nude; Naproxen; Nitrophenols; Organophosphates; Organophosphorus Compounds; Phenylglyoxal; Stomach Neoplasms; Sulindac; Transfection; Valproic Acid; Xenograft Model Antitumor Assays | 2012 |
Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; ATP-Binding Cassette Transporters; Biological Transport, Active; Cytochrome P-450 Enzyme System; Diclofenac; Electron Transport; Genes, MDR; Ibuprofen; Indomethacin; Ketoprofen; Ketorolac; Mitochondria; Naproxen; Reactive Oxygen Species; Sulindac; Tolmetin; Yeasts | 2012 |
Functionalized (poly(ɛ-caprolactone))₂-poly(ethylene glycol) nanoparticles with grafting nicotinic acid as drug carriers.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Cells, Cultured; Chemistry, Pharmaceutical; Diffusion; Drug Carriers; Drug Compounding; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Indomethacin; Kinetics; Models, Chemical; Nanoparticles; Nanotechnology; Niacin; Particle Size; Polyesters; Polyethylene Glycols; Solubility; Technology, Pharmaceutical | 2012 |
Failure of a repeat course of cyclooxygenase inhibitor to close a PDA is a risk factor for developing chronic lung disease in ELBW infants.
Topics: Chronic Disease; Cyclooxygenase Inhibitors; Drug Administration Schedule; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Extremely Low Birth Weight; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Ligation; Logistic Models; Lung Diseases; Male; Multivariate Analysis; Retrospective Studies; Risk Factors; Treatment Failure | 2012 |
Oral ibuprofen for patent ductus arteriosus: effective and safe or just cheap? Commentary on R. Neumann et al.: Oral ibuprofen versus intravenous ibuprofen or intravenous indomethacin for the treatment of patent ductus arteriosus in preterm infants: a sys
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin | 2012 |
Does treatment of patent ductus arteriosus with cyclooxygenase inhibitors affect neonatal regional tissue oxygenation?
Topics: Analysis of Variance; Blood Gas Analysis; Cerebrovascular Circulation; Chi-Square Distribution; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Echocardiography, Doppler; Female; Hemodynamics; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Oximetry; Oxygen Consumption; Pregnancy; Prospective Studies; Renal Circulation; Splanchnic Circulation; Statistics, Nonparametric | 2012 |
Patent ductus arteriosus in premature neonates.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Ligation; Risk Factors | 2012 |
Ibubrofen in the treatment of patent ductus arteriosus in preterm infants: what we know, what we still do not know.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Evidence-Based Medicine; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Randomized Controlled Trials as Topic; Treatment Outcome | 2012 |
A discriminatory intrinsic dissolution study using UV area imaging analysis to gain additional insights into the dissolution behaviour of active pharmaceutical ingredients.
Topics: Chemistry, Pharmaceutical; Drug Design; Ibuprofen; Indomethacin; Sodium Dodecyl Sulfate; Solubility; Spectrum Analysis, Raman; Technology, Pharmaceutical; Theophylline; Ultraviolet Rays; X-Ray Diffraction | 2012 |
Selective COX-2 inhibitor ameliorates osteoarthritis by repressing apoptosis of chondrocyte.
Topics: Animals; Apoptosis; Cartilage, Articular; Celecoxib; Chondrocytes; Collagen Type II; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Humans; Ibuprofen; Indomethacin; Osteoarthritis; Pyrazoles; Rats; Rats, Wistar; Sulfonamides | 2012 |
Inhibition of mitochondrial complex I by various non-steroidal anti-inflammatory drugs and its protection by quercetin via a coenzyme Q-like action.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caco-2 Cells; Diclofenac; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electron Transport Complex I; Humans; Ibuprofen; Indomethacin; Mitochondria; Multienzyme Complexes; NAD; Piroxicam; Protective Agents; Quercetin; Rats; Ubiquinone | 2012 |
Oral ibuprofen for treatment of patent ductus arteriosus: more than a cheap alternative?
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin | 2012 |
Thiazolo[3,2-b]-1,2,4-triazole-5(6H)-one substituted with ibuprofen: novel non-steroidal anti-inflammatory agents with favorable gastrointestinal tolerance.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Dose-Response Relationship, Drug; Drug Tolerance; Edema; Female; Ibuprofen; Indomethacin; Male; Mice; Pain Measurement; Stomach; Stomach Ulcer; Structure-Activity Relationship; Triazoles | 2012 |
Thrombocytopenia in the first 24 hours after birth and incidence of patent ductus arteriosus.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Echocardiography, Doppler; Female; Humans; Ibuprofen; Indomethacin; Infant, Extremely Low Birth Weight; Infant, Newborn; Infant, Very Low Birth Weight; Male; Platelet Count; Sepsis; Thrombocytopenia | 2012 |
Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3.
Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anti-Inflammatory Agents, Non-Steroidal; Flufenamic Acid; Flurbiprofen; Hydroxyprostaglandin Dehydrogenases; Ibuprofen; Indomethacin; Meclofenamic Acid; Mefenamic Acid; Naproxen; Sulindac; Tolmetin | 2012 |
Comparative evaluation for the use of oral ibuprofen and intravenous indomethacin in Korean infants with patent ductus.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Comorbidity; Ductus Arteriosus, Patent; Female; Humans; Hyponatremia; Ibuprofen; Incidence; Indomethacin; Infant, Newborn; Infant, Premature; Injections, Intravenous; Intracranial Hemorrhages; Male; Off-Label Use; Renal Insufficiency; Republic of Korea; Respiratory Distress Syndrome, Newborn; Retrospective Studies | 2012 |
Pharmaco-modulations of induced edema and vascular permeability changes by Vipera lebetina venom: inflammatory mechanisms.
Topics: Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Cromolyn Sodium; Crotalid Venoms; Cyproheptadine; Edema; Histamine Release; Ibuprofen; Indomethacin; Inflammation; Loratadine; Male; Mice; Serotonin; Vasodilation | 2013 |
Oral ibuprofen versus intravenous indomethacin for closure of patent ductus arteriosus in very low birth weight infants.
Topics: Administration, Intravenous; Administration, Oral; Ductus Arteriosus, Patent; Enterocolitis, Necrotizing; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Very Low Birth Weight; Male; Retrospective Studies | 2012 |
Diclofenac enhances proinflammatory cytokine-induced aquaporin-4 expression in cultured astrocyte.
Topics: Animals; Aquaporin 4; Astrocytes; Blotting, Western; Cells, Cultured; Cyclooxygenase Inhibitors; Cytokines; Diclofenac; Gene Expression Regulation; Ibuprofen; Immunohistochemistry; Indomethacin; Inflammation Mediators; NF-kappa B; Rats; Rats, Wistar | 2013 |
Effectiveness and safety of indomethacin versus ibuprofen for the treatment of patent ductus arteriosus in preterm infants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Enterocolitis, Necrotizing; Female; Gastrointestinal Hemorrhage; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Intestinal Perforation; Male; Renal Insufficiency; Retrospective Studies | 2013 |
Salbutamol sulfate absorption across Calu-3 bronchial epithelia cell monolayer is inhibited in the presence of common anionic NSAIDs.
Topics: Adrenergic beta-2 Receptor Agonists; Albuterol; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biological Transport; Blotting, Western; Cell Line; Drug Interactions; Epithelial Cells; Humans; Ibuprofen; Indomethacin; Respiratory Mucosa; Tight Junctions; Transendothelial and Transepithelial Migration | 2013 |
Preparation and characterization of multiactive electrospun fibers: poly-ɛ-carpolactone fibers loaded with hydroxyapatite and selected NSAIDs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Drug Delivery Systems; Durapatite; Ibuprofen; Indomethacin; Microscopy, Electron, Scanning; Polyesters; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2014 |
Effect of NSAIDs and diuretics on nephrogenesis in an ex vivo embryogenic kidney model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Morphogenetic Protein 7; Diuretics; Female; Fibroblast Growth Factor 8; Furosemide; Gene Expression; Gene Expression Profiling; Glial Cell Line-Derived Neurotrophic Factor; Hydrochlorothiazide; Ibuprofen; Indomethacin; Kidney; Mice; Mice, Inbred ICR; Organ Culture Techniques; Pregnancy; SOX9 Transcription Factor; WT1 Proteins | 2013 |
Ibuprofen versus indomethacin treatment of patent ductus arteriosus: comparative effectiveness and complications.
Topics: Bronchopulmonary Dysplasia; Creatinine; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Intestinal Perforation; Male; Retrospective Studies | 2014 |
Transdermal enhancement effect and mechanism of iontophoresis for non-steroidal anti-inflammatory drugs.
Topics: 1-Octanol; Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carrageenan; Diffusion; Edema; Foot; Ibuprofen; In Vitro Techniques; Indomethacin; Iontophoresis; Male; Rats, Sprague-Dawley; Skin; Water | 2014 |
Eosinophilic pustular folliculitis clinically presenting as orofacial granuloma: successful treatment with indomethacin, but not ibuprofen.
Topics: Biopsy; Cyclooxygenase Inhibitors; Diagnosis, Differential; Drug Substitution; Eosinophilia; Female; Folliculitis; Granulomatosis, Orofacial; Humans; Ibuprofen; Indomethacin; Middle Aged; Predictive Value of Tests; Skin Diseases, Vesiculobullous; Treatment Outcome | 2015 |
Practical approach to prepare solid dispersion drug product using spherical silicate.
Topics: Crystallization; Ibuprofen; Indomethacin; Particle Size; Phenytoin; Porosity; Silicates; Solubility; Solutions; Surface Properties; Technology, Pharmaceutical | 2014 |
Indomethacin administered early in the postnatal period results in reduced glomerular number in the adult rat.
Topics: Animals; Animals, Newborn; Body Weight; Cyclooxygenase Inhibitors; Female; Ibuprofen; Indomethacin; Kidney Glomerulus; Pregnancy; Rats, Sprague-Dawley; Tocolytic Agents | 2014 |
In vivo predictive dissolution: transport analysis of the CO2 , bicarbonate in vivo buffer system.
Topics: Bicarbonates; Buffers; Carbon Dioxide; Chemistry, Pharmaceutical; Diffusion; Equipment Design; Hydrogen-Ion Concentration; Ibuprofen; Indomethacin; Ketoprofen; Kinetics; Models, Chemical; Solubility; Technology, Pharmaceutical | 2014 |
Hospital variation in medical and surgical treatment of patent ductus arteriosus.
Topics: Birth Weight; California; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Gestational Age; Hospitals; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Ligation; Logistic Models; Male; Odds Ratio; Practice Patterns, Physicians'; Respiratory Distress Syndrome, Newborn; Risk Factors | 2015 |
Variation and comparative effectiveness of patent ductus arteriosus pharmacotherapy in extremely low birth weight infants.
Topics: Cohort Studies; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Extremely Low Birth Weight; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Regression Analysis; Retrospective Studies; Treatment Outcome | 2014 |
Indomethacin vs ibuprofen: comparison of efficacy in the setting of conservative therapeutic approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Birth Weight; Creatinine; Ductus Arteriosus, Patent; Female; Gestational Age; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Male; Treatment Outcome | 2015 |
Timing of pharmacological treatment for patent ductus arteriosus and risk of secondary surgery, death or bronchopulmonary dysplasia: a population-based cohort study of extremely preterm infants.
Topics: Bronchopulmonary Dysplasia; Cohort Studies; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Gestational Age; Humans; Ibuprofen; Indomethacin; Infant, Extremely Premature; Infant, Newborn; Logistic Models; Male; Sweden; Time-to-Treatment | 2015 |
A systematic evaluation of hydroxyethyl starch as a potential nanocarrier for parenteral drug delivery.
Topics: Animals; Biocompatible Materials; Colloids; Drug Carriers; Drug Delivery Systems; Drug Liberation; Freeze Drying; Humans; Hydroxyethyl Starch Derivatives; Ibuprofen; Indomethacin; Materials Testing; Nanoparticles; Rats; Spectrum Analysis, Raman; Toxicity Tests, Acute | 2015 |
FXR antagonism of NSAIDs contributes to drug-induced liver injury identified by systems pharmacology approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Genetic Predisposition to Disease; Hep G2 Cells; Humans; Ibuprofen; Indomethacin; Luciferases; Phosphorylation; Protein Interaction Maps; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; STAT3 Transcription Factor; Systems Biology; Transcription, Genetic; Transcriptional Activation; Two-Hybrid System Techniques | 2015 |
Antioxidants and Biomarkers of Oxidative Stress in Preterm Infants with Symptomatic Patent Ductus Arteriosus.
Topics: Antioxidants; Biomarkers; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant; Infant, Newborn; Infant, Premature; Ligation; Male; Oxidative Stress; Pilot Projects; Prospective Studies | 2015 |
The importance of echocardiography and an individual approach to patent ductus arteriosus treatment in extremely preterm infants.
Topics: Bronchopulmonary Dysplasia; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Extremely Premature; Male | 2015 |
Adequate timely treatment of patent ductus arteriosus in extremely low birth weight infants: an ongoing challenge.
Topics: Bronchopulmonary Dysplasia; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Extremely Premature; Male | 2015 |
NSAIDs and spontaneous abortions - true effect or an indication bias?
Topics: Abortion, Spontaneous; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Humans; Ibuprofen; Indomethacin; Israel; Middle Aged; Naproxen; Pregnancy; Retrospective Studies; Time Factors; Young Adult | 2015 |
Future Benefits of Sequential Echocardiography: Unmasking the Indications for Treatment of Patent Ductus Arteriosus in Extremely Preterm Infants.
Topics: Bronchopulmonary Dysplasia; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Extremely Premature; Male | 2015 |
Locally Delivered Nonsteroidal Antiinflammatory Drug: A Potential Option for Heterotopic Ossification Prevention.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Proliferation; Cell Survival; Cells, Cultured; Disease Models, Animal; DNA Replication; Female; Humans; Ibuprofen; Indomethacin; Ketorolac; Male; Ossification, Heterotopic; Osteoblasts; Rats; Skin; Time Factors; Wound Healing; Wounds and Injuries | 2015 |
Evaluation of changes in oral drug absorption in preterm and term neonates for Biopharmaceutics Classification System (BCS) class I and II compounds.
Topics: Acetaminophen; Administration, Oral; Biopharmaceutics; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Intestinal Absorption; Theophylline | 2016 |
Comparative effectiveness and safety of indomethacin versus ibuprofen for the treatment of patent ductus arteriosus.
Topics: Cardiovascular Agents; Databases, Factual; Ductus Arteriosus, Patent; Female; Gestational Age; Humans; Ibuprofen; Indomethacin; Infant; Infant, Extremely Premature; Infant, Newborn; Intensive Care Units, Neonatal; Male; Treatment Outcome | 2015 |
Novel nanostructured supramolecular hydrogels for the topical delivery of anionic drugs.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dermatitis; Drug Compounding; Drug Delivery Systems; Drug Liberation; Drug Stability; Humans; Hydrogels; Ibuprofen; Imidazoles; In Vitro Techniques; Indomethacin; Nanofibers; Nanostructures; Rabbits; Skin Absorption; Skin Tests; Tissue Distribution | 2015 |
NSAIDs Ibuprofen, Indometacin, and Diclofenac do not interact with Farnesoid X Receptor.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Survival; Diclofenac; Gene Expression; Gene Expression Regulation; Genes, Reporter; Humans; Ibuprofen; Indomethacin; Ligands; Protein Binding; Protein Interaction Domains and Motifs; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Reproducibility of Results; Time Factors | 2015 |
Pharmacological characterization of intraplantar Complete Freund's Adjuvant-induced burrowing deficits.
Topics: Amines; Analgesics; Animals; Antibodies; Behavior, Animal; Celecoxib; Cyclohexanecarboxylic Acids; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; Ibuprofen; Indomethacin; Inflammation; Male; Morphine; Motor Activity; Nerve Growth Factor; Pain; Rats, Wistar; Tramadol | 2016 |
Treatment of Patent Ductus Arteriosus with Cyclo-oxygenase Inhibitors beyond 2 Weeks of Age in Very Low Birth Weight Infants.
Topics: Connecticut; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant; Infant, Extremely Premature; Infant, Newborn; Infant, Very Low Birth Weight; Intensive Care Units, Neonatal; Length of Stay; Ligation; Logistic Models; Male; Multivariate Analysis; Retrospective Studies; Treatment Outcome | 2016 |
Oscillatory Shear Rheology in Examining the Drug-Polymer Interactions Relevant in Hot Melt Extrusion.
Topics: Acetaminophen; Excipients; Hot Temperature; Ibuprofen; Indomethacin; Models, Chemical; Pharmaceutical Preparations; Phase Transition; Plasticizers; Polyethylene Glycols; Rheology; Solubility; Technology, Pharmaceutical; Thermography; Transition Temperature; Viscosity | 2016 |
Nonsteroidal anti-inflammatory administration and patent ductus arteriosus ligation, a survey of practice preferences at US children's hospitals.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Consensus; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Ligation; Neonatology; Outcome Assessment, Health Care; Practice Guidelines as Topic; Practice Patterns, Physicians'; Surveys and Questionnaires | 2016 |
Indomethacin inhibits tetrodotoxin-resistant Na(+) channels at acidic pH in rat nociceptive neurons.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Female; Hydrogen-Ion Concentration; Ibuprofen; Indomethacin; Kinetics; Male; Membrane Potentials; Naproxen; Nociceptors; Patch-Clamp Techniques; Rats, Sprague-Dawley; Sodium Channels; Trigeminal Ganglion | 2016 |
Editorial: Patent Ductus Arteriosus in Extremely Premature Neonates.
Topics: Anterior Cerebral Artery; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Echocardiography, Doppler, Pulsed; Female; Hemodynamics; Humans; Ibuprofen; Indomethacin; Infant, Extremely Premature; Infant, Newborn; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Practice Guidelines as Topic; Pregnancy | 2016 |
Effectiveness and safety of treatments used for the management of patent ductus arteriosus (PDA) in preterm infants: a protocol for a systematic review and network meta-analysis.
Topics: Acetaminophen; Administration, Oral; Bayes Theorem; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant; Infant Mortality; Infant, Newborn; Infant, Premature; Network Meta-Analysis; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Systematic Reviews as Topic | 2016 |
(1)H-Nuclear magnetic resonance-based metabolic profiling of nonsteroidal anti-inflammatory drug-induced adverse effects in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug-Related Side Effects and Adverse Reactions; Gastric Mucosa; Ibuprofen; Indomethacin; Least-Squares Analysis; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Metabolomics; Piroxicam; Rats; Rats, Sprague-Dawley | 2016 |
The Role of Paracetamol for Closing Patent Ductus Arteriosus. A Challenging Alternative for Ductal Closure?
Topics: Acetaminophen; Administration, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; Cerebral Hemorrhage; Contraindications; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Klebsiella Infections; Ligation; Male; Neonatal Sepsis; Thrombocytopenia | 2016 |
Trends and variation in management and outcomes of very low-birth-weight infants with patent ductus arteriosus.
Topics: Cyclooxygenase Inhibitors; Databases, Factual; Ductus Arteriosus, Patent; Female; Hospitals, Pediatric; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Very Low Birth Weight; Ligation; Male; Retrospective Studies; Treatment Outcome; United States | 2016 |
Inhibitors of oxidative and hydrolytic endocannabinoid degradation do not enhance depolarization-induced suppression of excitation on dorsal cochlear nucleus glycinergic neurons.
Topics: Animals; Calcium; Cochlear Nucleus; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Endocannabinoids; Glycine; Ibuprofen; Indomethacin; Male; Neuronal Plasticity; Neurons; Rats; Rats, Wistar; Salicylates; Synaptic Potentials | 2017 |
Non-steroidal anti-inflammatory drugs in the watercourses of Elbe basin in Czech Republic.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Czech Republic; Diclofenac; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Rivers; Water Pollutants, Chemical | 2017 |
Management of Patent Ductus Arteriosus: Are We Looking at the Right Outcomes?
Topics: Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Persistent Fetal Circulation Syndrome | 2017 |
[Digestive and Kidney Complications by indomethacin and ibuprofen in extreme preterm infants with patent ductus arteriosus].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Enterocolitis; Female; Humans; Ibuprofen; Indomethacin; Infant, Extremely Premature; Infant, Newborn; Male; Renal Insufficiency; Retrospective Studies | 2017 |
Trends in Patent Ductus Arteriosus Diagnosis and Management for Very Low Birth Weight Infants.
Topics: California; Cohort Studies; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Very Low Birth Weight; Ligation; Logistic Models; Male; Retrospective Studies | 2017 |
Changes in the Diagnosis and Management of Patent Ductus Arteriosus from 2006 to 2015 in United States Neonatal Intensive Care Units.
Topics: Cyclooxygenase Inhibitors; Databases, Factual; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Ligation; United States | 2017 |
Spray drying of poorly soluble drugs from aqueous arginine solution.
Topics: Arginine; Calorimetry, Differential Scanning; Chromatography, High Pressure Liquid; Desiccation; Drug Combinations; Drug Compounding; Ibuprofen; Indomethacin; Powder Diffraction; Solubility; Solutions; Solvents; Spectroscopy, Fourier Transform Infrared; Water; X-Ray Diffraction | 2017 |
Ibuprofen and indomethacin differentially regulate vascular endothelial growth factor and its receptors in ductus arteriosus endothelial cells.
Topics: Animals; Aorta; Cell Culture Techniques; Cyclooxygenase Inhibitors; Ductus Arteriosus; Endothelial Cells; Female; Fetus; Fluorescent Antibody Technique; Ibuprofen; Indomethacin; Rats; Rats, Wistar; RNA, Messenger; Vascular Endothelial Growth Factors | 2018 |
Numerical simulation of hot-melt extrusion processes for amorphous solid dispersions using model-based melt viscosity.
Topics: Carbamazepine; Computer Simulation; Dipyridamole; Drug Compounding; Ibuprofen; Indomethacin; Models, Chemical; Numerical Analysis, Computer-Assisted; Pharmaceutical Preparations; Phase Transition; Plasticizers; Polyethylene Glycols; Pyrrolidines; Rheology; Software; Technology, Pharmaceutical; Transition Temperature; Vinyl Compounds; Viscosity | 2018 |
Understanding the mode of binding mechanism of doripenem to human serum albumin: Spectroscopic and molecular docking approaches.
Topics: Anti-Bacterial Agents; Binding Sites; Binding, Competitive; Diazepam; Doripenem; Humans; Hydrogen Bonding; Ibuprofen; Indomethacin; Kinetics; Molecular Docking Simulation; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Serum Albumin, Human; Solutions; Static Electricity; Temperature; Thermodynamics; Warfarin | 2018 |
A fast and reliable DSC-based method to determine the monomolecular loading capacity of drugs with good glass-forming ability in mesoporous silica.
Topics: Calorimetry, Differential Scanning; Carbazoles; Carvedilol; Cinnarizine; Drug Stability; Glass; Ibuprofen; Indomethacin; Porosity; Propanolamines; Silicon Dioxide | 2018 |
Is paracetamol as effective as indomethacin or ibuprofen in closing a hemodynamically significant patent ductus arteriosus in preterm infants?
Topics: Acetaminophen; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature | 2018 |
Patent ductus arteriosus in preterm infants born before 30 weeks' gestation: high rate of spontaneous closure after hospital discharge.
Topics: Administration, Intravenous; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Follow-Up Studies; Gestational Age; Humans; Ibuprofen; Indomethacin; Infant; Infant, Extremely Low Birth Weight; Infant, Extremely Premature; Infant, Newborn; Italy; Ligation; Male; Patient Discharge; Remission Induction; Remission, Spontaneous; Retrospective Studies | 2018 |
Preparation and characterization of multi-component tablets containing co-amorphous salts: Combining multimodal non-linear optical imaging with established analytical methods.
Topics: Administration, Oral; Arginine; Chemistry, Pharmaceutical; Drug Combinations; Drug Stability; Excipients; Ibuprofen; Indomethacin; Mannitol; Optical Imaging; Povidone; Salts; Solubility; Spectroscopy, Fourier Transform Infrared; Tablets; Technology, Pharmaceutical; X-Ray Diffraction; Xylitol | 2018 |
Long-Term Neurodevelopment of Low-Birthweight, Preterm Infants with Patent Ductus Arteriosus.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Follow-Up Studies; Humans; Ibuprofen; Incidence; Indomethacin; Infant; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Longitudinal Studies; Male; Neurodevelopmental Disorders; Risk Assessment; Time; Time Factors | 2018 |
What is the Most Efficacious Pharmacological Therapy for Patent Ductus Arteriosus Closure in Premature Infants?
Topics: Acetaminophen; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant; Infant, Newborn; Infant, Premature | 2018 |
Physical Stability of an Amorphous Sugar Matrix Dried From Methanol as an Amorphous Solid Dispersion Carrier and the Influence of Heat Treatment.
Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Curcumin; Desiccation; Drug Compounding; Drug Stability; Excipients; Hot Temperature; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Indomethacin; Maltose; Methanol; Phase Transition; Solubility; Solvents; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 2019 |
Does Postmenstrual Age Affect Medical Patent Ductus Arteriosus Treatment Success in Preterm Infants?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Female; Gestational Age; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Ligation; Male; Pregnancy; Prenatal Care; Retrospective Studies; Steroids; Treatment Outcome | 2019 |
Comparison of efficacy and safety of oral ibuprofen versus oral indomethacin.
Topics: Birth Weight; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Very Low Birth Weight | 2019 |
Larger Dose Reductions of Vancomycin Required in Neonates with Patent Ductus Arteriosus Receiving Indomethacin versus Ibuprofen.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Male; Monte Carlo Method; Pregnancy; Vancomycin; Young Adult | 2019 |
Vascular endothelial growth factor polymorphism rs2010963 status does not affect patent ductus arteriosus incidence or cyclooxygenase inhibitor treatment success in preterm infants.
Topics: Case-Control Studies; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Incidence; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Polymorphism, Genetic; Treatment Outcome; Vascular Endothelial Growth Factor A | 2019 |
Reply to letter to the editor: Comparison of efficacy and safety of oral ibuprofen versus oral indomethacin.
Topics: Birth Weight; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Very Low Birth Weight | 2019 |
Celecoxib, ibuprofen, and indomethacin alleviate depression-like behavior induced by interferon-alfa in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Celecoxib; Depression; Disease Models, Animal; Exercise Test; Ibuprofen; Indomethacin; Interferon-alpha; Male; Mice | 2019 |
Effects of NSAIDs on the nanoscopic dynamics of lipid membrane.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Dimyristoylphosphatidylcholine; Ibuprofen; Indomethacin; Lipid Bilayers; Membrane Fluidity; Molecular Dynamics Simulation; Neutron Diffraction; Scattering, Small Angle | 2020 |
Solubility of pharmaceutical ingredients in triglycerides.
Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Drug Compounding; Drug Delivery Systems; Excipients; Fenofibrate; Ibuprofen; Indomethacin; Lipids; Pharmaceutical Preparations; Solubility; Triglycerides | 2019 |
The influence on renal function of ibuprofen treatment for patent ductus arteriosus in extremely low birthweight infants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Birth Weight; Case-Control Studies; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant, Extremely Low Birth Weight; Infant, Newborn; Infant, Premature; Japan; Male | 2020 |
Neonatal Intensive Care Unit-Level Patent Ductus Arteriosus Treatment Rates and Outcomes in Infants Born Extremely Preterm.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Canada; Cardiovascular Surgical Procedures; Cerebral Intraventricular Hemorrhage; Cohort Studies; Ductus Arteriosus, Patent; Echocardiography; Enterocolitis, Necrotizing; Europe; Female; Humans; Ibuprofen; Indomethacin; Infant, Extremely Premature; Infant, Newborn; Intensive Care Units, Neonatal; Israel; Japan; Leukomalacia, Periventricular; Linear Models; Male; Retrospective Studies | 2020 |
Solubility of Pharmaceutical Ingredients in Natural Edible Oils.
Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cinnarizine; Coconut Oil; Drug Compounding; Drug Delivery Systems; Excipients; Felodipine; Fenofibrate; Griseofulvin; Ibuprofen; Indomethacin; Models, Molecular; Naproxen; Plant Oils; Solubility; Soybean Oil; Spectrum Analysis, Raman; Thermodynamics; Transition Temperature; Triglycerides | 2020 |
The design and development of high drug loading amorphous solid dispersion for hot-melt extrusion platform.
Topics: Chemistry, Pharmaceutical; Drug Carriers; Drug Stability; Drug Storage; Excipients; Humidity; Ibuprofen; Indomethacin; Naproxen; Polymers; Polymethacrylic Acids; Solubility; Thermodynamics | 2020 |
Oral ibuprofen promoted cholestatic liver disease in very low birth weight infants with patent ductus arteriosus.
Topics: Birth Weight; Cholestasis; Ductus Arteriosus, Patent; Emulsions; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Liver Diseases; Retrospective Studies; Thrombocytopenia | 2021 |
Drug exposure for PDA closure in France: a prospective, cohort-based, analysis.
Topics: Acetaminophen; Administration, Oral; Drug Resistance; Drug Utilization; Ductus Arteriosus, Patent; Female; France; Furosemide; Hospitalization; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Male; Practice Patterns, Physicians'; Prospective Studies; Treatment Outcome | 2020 |
Differential actions of indomethacin: clinical relevance in headache.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Headache; Humans; Ibuprofen; Indomethacin; Naproxen | 2021 |
Aminoglycosides were associated with higher rates of surgical patent ductus arteriosus closure in preterm infants.
Topics: Aminoglycosides; Anti-Bacterial Agents; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant; Infant, Newborn; Infant, Premature | 2021 |
Effect of In Utero Non-Steroidal Anti-Inflammatory Drug Therapy for Severe Ebstein Anomaly or Tricuspid Valve Dysplasia (NSAID Therapy for Fetal Ebstein anomaly).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Constriction; Ductus Arteriosus; Duration of Therapy; Ebstein Anomaly; Echocardiography; Female; Fetal Heart; Fetal Therapies; Gestational Age; Heart Defects, Congenital; Humans; Ibuprofen; Indomethacin; Live Birth; Maternal-Fetal Exchange; Perinatal Mortality; Pregnancy; Pulmonary Valve Insufficiency; Retrospective Studies; Treatment Outcome; Tricuspid Valve; Tricuspid Valve Insufficiency; Ultrasonography, Doppler; Ultrasonography, Prenatal | 2021 |
Association between changes in urine output and successful indomethacin treatment for patent ductus arteriosus in preterm neonates.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Retrospective Studies | 2021 |
PATENT DUCTUS ARTERIOSUS CLOSURE: EXPERIENCE FROM A TERTIARY REFERRAL CENTER.
Topics: Acetaminophen; Ductus Arteriosus, Patent; Female; Gestational Age; Humans; Ibuprofen; Indomethacin; Infant; Infant, Extremely Premature; Infant, Newborn; Infant, Very Low Birth Weight; Male; Premature Birth; Retrospective Studies; Tertiary Care Centers | 2020 |
Is ibuprofen superior to indomethacin for patent ductus arteriosus in Japanese preterm infants?
Topics: Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Japan | 2021 |
Experimental evidence for proarrhythmic effects of nonsteroidal anti-inflammatory drugs in a sensitive whole-heart model.
Topics: Action Potentials; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arrhythmias, Cardiac; Cardiac Electrophysiology; Diclofenac; Dose-Response Relationship, Drug; Electrocardiography; Female; Ibuprofen; Indomethacin; Isolated Heart Preparation; Rabbits; Tachycardia, Ventricular | 2022 |
Chloropyridinyl Esters of Nonsteroidal Anti-Inflammatory Agents and Related Derivatives as Potent SARS-CoV-2 3CL Protease Inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Chlorocebus aethiops; Coronavirus 3C Proteases; COVID-19 Drug Treatment; Esters; Halogenation; Humans; Ibuprofen; Indomethacin; Molecular Docking Simulation; Protease Inhibitors; Pyridines; Salicylic Acid; SARS-CoV-2; Vero Cells | 2021 |
Survey highlighting the lack of consensus on diagnosis and treatment of patent ductus arteriosus in prematurity.
Topics: Consensus; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Surveys and Questionnaires | 2022 |
Impact of drug aggregation on the structural and dynamic properties of Triton X-100 micelles.
Topics: Ibuprofen; Indomethacin; Micelles; Octoxynol; Surface-Active Agents; Water | 2022 |
Factorial design in the optimization and study 'in combo' of derivatives of imidazo[1,2-a]azines in the COX´s isoforms inhibition.
Topics: Animals; Cyclooxygenase 2; Ibuprofen; Indomethacin; Mice; Molecular Docking Simulation; Protein Isoforms; Pyrimidines; Structure-Activity Relationship | 2022 |
An Evolving Role of Aqueous Piperazine to Improve the Solubility of Non-Steroidal Anti-Inflammatory Drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Flurbiprofen; Ibuprofen; Indomethacin; Ketoprofen; Phenylbutazone; Piperazine; Powders; Salts; Solubility; Spectroscopy, Fourier Transform Infrared; Sulindac; Water; X-Ray Diffraction | 2022 |
Management of patent ductus arteriosus in very preterm infants in England and Wales: a retrospective cohort study.
Topics: Ductus Arteriosus, Patent; Female; Fetal Growth Retardation; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Retrospective Studies; Wales | 2022 |
Oral Ibuprofen Is More Effective than Intravenous Ibuprofen for Closure of a Patent Ductus Arteriosus: Can Pharmacokinetic Modeling Help Us to Understand Why?
Topics: Administration, Oral; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature | 2023 |
Predictors of a non-response to prophylactic indomethacin for patent ductus arteriosus in preterm infants.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indomethacin; Infant; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Premature Birth; Retrospective Studies | 2023 |
Association between gastrointestinal perforation and patent ductus arteriosus in extremely-low-birth-weight infants: a retrospective study of our decade-long experience.
Topics: Ductus Arteriosus, Patent; Enterocolitis, Necrotizing; Humans; Ibuprofen; Indomethacin; Infant, Extremely Low Birth Weight; Infant, Newborn; Infant, Premature; Intestinal Perforation; Retrospective Studies | 2023 |
New NSAID Conjugates as Potent and Selective COX-2 Inhibitors: Synthesis, Molecular Modeling and Biological Investigation.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Edema; Ibuprofen; Indomethacin; Molecular Docking Simulation; Rats; Structure-Activity Relationship | 2023 |
Evaluation of Health-Related Values and Preferences of Adults Who Were Preterm Infants and Parents of Preterm Infants Concerning Use of Prophylactic Cyclooxygenase Inhibitor Drugs.
Topics: Acetaminophen; Adult; Cerebral Hemorrhage; Child; Cross-Sectional Studies; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Hydrocortisone; Ibuprofen; Indomethacin; Infant; Infant, Newborn; Infant, Premature; Parents | 2023 |
Detailed Experimental and In Silico Investigation of Indomethacin Binding with Human Serum Albumin Considering Primary and Secondary Binding Sites.
Topics: Binding Sites; Circular Dichroism; Hemin; Humans; Ibuprofen; Indomethacin; Molecular Docking Simulation; Protein Binding; Serum Albumin, Human; Spectrometry, Fluorescence; Thermodynamics; Warfarin | 2023 |
Cost-Effectiveness Analysis of Ibuprofen Versus Indomethacin or Paracetamol for the Treatment of Patent Ductus Arteriosus in Preterm Neonates.
Topics: Acetaminophen; Cost-Effectiveness Analysis; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature | 2023 |
Efficacy of ibuprofen and indomethacin as prophylaxis of heterotopic ossification: a comparative study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Ossification, Heterotopic | 2023 |