ibuprofen and ibuprofen acyl glucuronide

ibuprofen has been researched along with ibuprofen acyl glucuronide in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's1 (12.50)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T1
Castillo, M; Smith, PC2
Castillo, M; Dooley, MA; Lam, YW; Smith, PC; Stahl, E1
Lindon, JC; Nicholson, JK; Troke, J; Vanderhoeven, SJ; Wilson, ID1
Boyle, B; Bristow, AW; Creaser, CS; Ray, A; Reynolds, JC; Sage, A; Smith, RW; Toutoungi, DE; Weston, DJ; Wilson, ID1
Fujiwara, R; Hashimoto, M; Itoh, T; Narawa, T; Takenaka, S1
De Logu, F; De Siena, G; Geppetti, P; Landini, L; Li Puma, S; Nassini, R; Patacchini, R; Poli, G; Preti, D; Tsagareli, MG; Tuccinardi, T1

Other Studies

8 other study(ies) available for ibuprofen and ibuprofen acyl glucuronide

ArticleYear
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney

2011
Disposition and reactivity of ibuprofen and ibufenac acyl glucuronides in vivo in the rhesus monkey and in vitro with human serum albumin.
    Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Buffers; Chromatography, High Pressure Liquid; Drug Stability; Female; Glucuronates; Humans; Hydrogen-Ion Concentration; Ibuprofen; Macaca mulatta; Male; Phenylacetates; Protein Binding; Serum Albumin

1995
Disposition and covalent binding of ibuprofen and its acyl glucuronide in the elderly.
    Clinical pharmacology and therapeutics, 1995, Volume: 57, Issue:6

    Topics: Administration, Oral; Aged; Aging; Glucuronates; Humans; Ibuprofen

1995
Direct determination of ibuprofen and ibuprofen acyl glucuronide in plasma by high-performance liquid chromatography using solid-phase extraction.
    Journal of chromatography, 1993, Apr-21, Volume: 614, Issue:1

    Topics: Chromatography, High Pressure Liquid; Glucuronates; Humans; Ibuprofen; Reproducibility of Results; Spectrophotometry, Ultraviolet

1993
NMR spectroscopic studies of the transacylation reactivity of ibuprofen 1-beta-O-acyl glucuronide.
    Journal of pharmaceutical and biomedical analysis, 2006, Jun-07, Volume: 41, Issue:3

    Topics: Acylation; Glucuronates; Hydrolysis; Ibuprofen; Magnetic Resonance Spectroscopy

2006
Enhanced performance in the determination of ibuprofen 1-β-O-acyl glucuronide in urine by combining high field asymmetric waveform ion mobility spectrometry with liquid chromatography-time-of-flight mass spectrometry.
    Journal of chromatography. A, 2013, Feb-22, Volume: 1278

    Topics: Chromatography, High Pressure Liquid; Glucuronates; Humans; Ibuprofen; Mass Spectrometry

2013
Expression of human solute carrier family transporters in skin: possible contributor to drug-induced skin disorders.
    Scientific reports, 2014, Jun-11, Volume: 4

    Topics: Biological Transport; Carrier Proteins; Cell Line; Cell Survival; Glucuronates; Humans; Ibuprofen; Intestine, Small; Keratinocytes; Liver; Membrane Transport Proteins; S100 Calcium Binding Protein A7; S100 Proteins; Skin; Skin Diseases

2014
The acyl-glucuronide metabolite of ibuprofen has analgesic and anti-inflammatory effects via the TRPA1 channel.
    Pharmacological research, 2019, Volume: 142

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Cell Line; Dinoprostone; Epithelial Cells; Glucuronates; Humans; Hyperalgesia; Ibuprofen; Interleukin-8; Male; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pain; Rats, Sprague-Dawley; TRPA1 Cation Channel

2019