Compounds > ibuprofen

ibuprofen and ibufenac

ibuprofen has been researched along with ibufenac in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (25.00)	18.7374
1990's	2 (16.67)	18.2507
2000's	0 (0.00)	29.6817
2010's	6 (50.00)	24.3611
2020's	1 (8.33)	2.80

Authors

Authors	Studies
van Dijk, J; Zwagemakers, JM	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Lund, C; Lynagh, T; Pless, SA; Romero-Rojo, JL	1
Kalgutkar, AS	1
Barfknecht, CF; Laban, SL; Rao, CS; Schoenwald, RD	1
Hoppel, CL; Minkler, PE	1
Heikkinen, L	1
Castillo, M; Smith, PC	1
Harding, JR; Iddon, L; Iqbal, M; Johnson, CH; Karlsson, E; Lindon, JC; Meng, X; Nicholson, JK; Sarda, S; Stachulski, AV; Wilson, ID	1

Reviews

1 review(s) available for ibuprofen and ibufenac

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

11 other study(ies) available for ibuprofen and ibufenac

Article	Year
Oxime ether derivatives, a new class of nonsteroidal antiinflammatory compounds. Journal of medicinal chemistry, 1977, Volume: 20, Issue:9 Topics: Animals; Anti-Inflammatory Agents; Ethers; Lethal Dose 50; Mice; Oximes; Rats; Structure-Activity Relationship	1977
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Molecular Basis for Allosteric Inhibition of Acid-Sensing Ion Channel 1a by Ibuprofen. Journal of medicinal chemistry, 2017, 10-12, Volume: 60, Issue:19 Topics: Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Allosteric Regulation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chick Embryo; Ibuprofen; Models, Molecular; Protein Conformation; Rats; Structure-Activity Relationship; Xenopus laevis	2017
Designing around Structural Alerts in Drug Discovery. Journal of medicinal chemistry, 2020, 06-25, Volume: 63, Issue:12 Topics: Drug Design; Drug Development; Drug Discovery; Drug-Related Side Effects and Adverse Reactions; Humans; Molecular Structure; Pharmaceutical Preparations; Structure-Activity Relationship	2020
Biopharmaceutical evaluation of ibufenac, ibuprofen, and their hydroxyethoxy analogs in the rabbit eye. Journal of pharmacokinetics and biopharmaceutics, 1992, Volume: 20, Issue:4 Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Eye; Female; Ibuprofen; In Vitro Techniques; Irritants; Male; Models, Statistical; Molecular Structure; Phenylacetates; Rabbits; Solubility; Water	1992
Determination of ibuprofen in human plasma by high-performance liquid chromatography. Journal of chromatography, 1988, Jul-15, Volume: 428, Issue:2 Topics: Chromatography, High Pressure Liquid; Humans; Ibuprofen; Phenylacetates; Reference Standards	1988
Silica capillary gas chromatographic determination of ibuprofen in serum. Journal of chromatography, 1984, Apr-13, Volume: 307, Issue:1 Topics: Chromatography, Gas; Humans; Ibuprofen; Phenylacetates; Silicon Dioxide	1984
Disposition and reactivity of ibuprofen and ibufenac acyl glucuronides in vivo in the rhesus monkey and in vitro with human serum albumin. Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:5 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Buffers; Chromatography, High Pressure Liquid; Drug Stability; Female; Glucuronates; Humans; Hydrogen-Ion Concentration; Ibuprofen; Macaca mulatta; Male; Phenylacetates; Protein Binding; Serum Albumin	1995
Integrated HPLC-MS and (1)H-NMR spectroscopic studies on acyl migration reaction kinetics of model drug ester glucuronides. Xenobiotica; the fate of foreign compounds in biological systems, 2010, Volume: 40, Issue:1 Topics: Acylation; Chromatography, High Pressure Liquid; Glucuronides; Humans; Hydrolysis; Ibuprofen; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Phenylacetates	2010