ibuprofen and flufenamic acid

ibuprofen has been researched along with flufenamic acid in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (35.14)	18.7374
1990's	5 (13.51)	18.2507
2000's	5 (13.51)	29.6817
2010's	13 (35.14)	24.3611
2020's	1 (2.70)	2.80

Authors

Authors	Studies
Inui, KI; Masuda, S; Saito, H	1
Inui, K; Saito, H; Uwai, Y	1
Charitos, C; Doulgkeris, C; Galanakis, D; Gavalas, A; Kourounakis, AP; Kourounakis, PN; Kravaritou, C; Rekka, EA; Tsiakitzis, KC	1
Chang, TK; Ensom, MH; Kiang, TK	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P	1
Bellman, K; Knegtel, RM; Settimo, L	1
Headey, SJ; Hughes, ML; Laguerre, A; Mohanty, B; Patil, R; Porter, CJ; Scanlon, MJ; Wielens, J; Williams, ML	1
Brewster, C; Deering-Rice, CE; Reilly, CA; Rose, TM	1
Kourounakis, PN; Kourti, M; Rekka, EA; Theodosis-Nobelos, P; Tziona, P	1
Bennis, K; Ducki, S; Lesage, F; Vivier, D	1
Gavalas, A; Kourti, M; Rekka, EA; Theodosis-Nobelos, P	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Kawai, K; Kuzuna, S; Morimoto, S	1
Cavalli-Björkman, K; Jacobson, J; Lundström, V; Nilsson, B; Norbeck, M	1
Hart, FD	1
Brooks, PM	1
Nagai, T; Nambu, N; Shimoda, M; Takahashi, Y; Ueda, H	1
Breckwoldt, M; Zahradnik, HP	1
Penning, TM; Smithgall, TE	1
Keat, AC; Keat, EC; Ravi, S	1
Gilfillan, AM; Rooney, SA	1
Machtey, I	1
Iizuka, Y; Tanaka, K	1
Owen, PR	1
Fraser, IS	1
Nakasaka, T; Okabe, N	1
Ando, HY; Murtha, JL	1
Goel, A; Raghava, GP; Singh, AM; Varshney, GC	1
Hashizume, N; Okabe, N	1
Klime, J; Kríz, J; Sochor, J	1
Atherton, J; Bauman, J; Kohl, C; Lam, W; Lou, Z; Mutlib, A; Reily, M; Walker, GS	1
Carvalho, G; Marques, R; Noronha, JP; Oehmen, A; Reis, MA; Salgado, R	1
Chai, MZ; Flanagan, JU; Squire, CJ; Teague, RM; Turnbull, AP; Yosaatmadja, Y	1
Ikushiro, S; Iwai, Y; Nishikawa, M; Sakaki, T; Sugimoto, H; Takita, T; Yasuda, K; Yasukawa, K; Yogo, Y	1

Reviews

2 review(s) available for ibuprofen and flufenamic acid

Article	Year
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics, 2005, Volume: 106, Issue:1 Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic	2005
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target? Journal of medicinal chemistry, 2016, 06-09, Volume: 59, Issue:11 Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship	2016

Article

Year

UDP-glucuronosyltransferases and clinical drug-drug interactions.

Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005

Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?

Journal of medicinal chemistry, 2016, 06-09, Volume: 59, Issue:11

Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Structure; Neuroprotective Agents; Pain; Potassium Channels, Tandem Pore Domain; Structure-Activity Relationship

2016

Trials

2 trial(s) available for ibuprofen and flufenamic acid

Article	Year
Prostaglandin synthetase inhibitors and dysmenorrhea. A survey and personal clinical experience. Acta obstetricia et gynecologica Scandinavica. Supplement, 1979, Volume: 87 Topics: Adolescent; Adult; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Evaluation; Dysmenorrhea; Female; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Naproxen; ortho-Aminobenzoates; Placebos; Prostaglandin Antagonists	1979
Prostaglandin synthetase inhibitors in the treatment of primary dysmenorrhea. Outcome trials reviewed. American journal of obstetrics and gynecology, 1984, Jan-01, Volume: 148, Issue:1 Topics: Clinical Trials as Topic; Cyclooxygenase Inhibitors; Dysmenorrhea; Female; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Naproxen	1984

Article

Year

Prostaglandin synthetase inhibitors and dysmenorrhea. A survey and personal clinical experience.

Acta obstetricia et gynecologica Scandinavica. Supplement, 1979, Volume: 87

Topics: Adolescent; Adult; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Evaluation; Dysmenorrhea; Female; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Naproxen; ortho-Aminobenzoates; Placebos; Prostaglandin Antagonists

1979

Prostaglandin synthetase inhibitors in the treatment of primary dysmenorrhea. Outcome trials reviewed.

American journal of obstetrics and gynecology, 1984, Jan-01, Volume: 148, Issue:1

Topics: Clinical Trials as Topic; Cyclooxygenase Inhibitors; Dysmenorrhea; Female; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Naproxen

1984

Other Studies

33 other study(ies) available for ibuprofen and flufenamic acid

Article	Year
Interactions of nonsteroidal anti-inflammatory drugs with rat renal organic anion transporter, OAT-K1. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:3 Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Carrier Proteins; Drug Interactions; Indomethacin; Ketoprofen; Kidney; Male; Methotrexate; Rats; Rats, Wistar; Tetraethylammonium Compounds	1997
Interaction between methotrexate and nonsteroidal anti-inflammatory drugs in organic anion transporter. European journal of pharmacology, 2000, Dec-01, Volume: 409, Issue:1 Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Carrier Proteins; Kinetics; Methotrexate; Oocytes; Probenecid; Uricosuric Agents; Xenopus laevis	2000
Synthesis and pharmacological evaluation of amide conjugates of NSAIDs with L-cysteine ethyl ester, combining potent antiinflammatory and antioxidant properties with significantly reduced gastrointestinal toxicity. Bioorganic & medicinal chemistry letters, 2004, Jul-16, Volume: 14, Issue:14 Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cholesterol; Cysteine; Drug Evaluation; Gastrointestinal Diseases; Lipoproteins, LDL; Mice; Rats; Triglycerides	2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions. Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21 Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence	2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Characterization of two distinct modes of drug binding to human intestinal fatty acid binding protein. ACS chemical biology, 2014, Nov-21, Volume: 9, Issue:11 Topics: Fatty Acid-Binding Proteins; Fluorescent Dyes; Humans; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Spectrometry, Fluorescence	2014
Inhibition of FAAH, TRPV1, and COX2 by NSAID-serotonin conjugates. Bioorganic & medicinal chemistry letters, 2014, Dec-15, Volume: 24, Issue:24 Topics: Amidohydrolases; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Flurbiprofen; Humans; Serotonin; TRPV Cation Channels	2014
Esters of some non-steroidal anti-inflammatory drugs with cinnamyl alcohol are potent lipoxygenase inhibitors with enhanced anti-inflammatory activity. Bioorganic & medicinal chemistry letters, 2015, Nov-15, Volume: 25, Issue:22 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cinnamates; Edema; Esters; Glycine max; Hyperlipidemias; Indoleacetic Acids; Lipoxygenase Inhibitors; Polyethylene Glycols; Propanols; Propionates; Rats; Thioctic Acid	2015
Amides of non-steroidal anti-inflammatory drugs with thiomorpholine can yield hypolipidemic agents with improved anti-inflammatory activity. Bioorganic & medicinal chemistry letters, 2016, Feb-01, Volume: 26, Issue:3 Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholesterol; Cholesterol, LDL; Edema; Hyperlipidemias; Hypolipidemic Agents; Morpholines; Rats; Triglycerides	2016
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Effects of some anti-rheumatic agents on copper-catalyzed thermal aggregation of gamma globulin. Agents and actions, 1979, Volume: 9, Issue:4 Topics: Anti-Inflammatory Agents; Aspirin; Copper; Dexamethasone; Diclofenac; Flufenamic Acid; gamma-Globulins; Gold Sodium Thiomalate; Hot Temperature; Humans; Ibuprofen; Indans; Indomethacin; Penicillamine; Phenylbutazone; Prednisolone	1979
The new antirheumatic drugs. Drugs, 1975, Volume: 9, Issue:5 Topics: Anti-Inflammatory Agents; Fenoprofen; Flufenamic Acid; Humans; Ibuprofen; Ketoprofen; Mefenamic Acid; Naproxen; Penicillamine; Phenylacetates; Rheumatic Diseases; Salicylates	1975
Nonsteroidal anti-inflammatory drug treatment for arthritis. Australian family physician, 1978, Volume: 7, Issue:8 Topics: Anti-Inflammatory Agents; Arthritis; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Naproxen; Oxyphenbutazone; Phenylbutazone; Salicylates	1978
Bioavailability of powdered inclusion compounds of nonsteroidal antiinflammatory drugs with beta-cyclodextrin in rabbits and dogs. Chemical & pharmaceutical bulletin, 1978, Volume: 26, Issue:10 Topics: Animals; Anti-Inflammatory Agents; Biological Availability; Dextrins; Dogs; Flufenamic Acid; Ibuprofen; Indomethacin; Ketoprofen; Powders; Rabbits; Starch	1978
[Drug therapy of dysmenorrhea]. Der Gynakologe, 1988, Volume: 21, Issue:1 Topics: Adrenergic beta-Agonists; Adult; Aspirin; Calcium Channel Blockers; Contraceptives, Oral; Dysmenorrhea; Female; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Magnesium; Mefenamic Acid; Models, Biological; Naproxen; Progestins	1988
Inhibition of trans-dihydrodiol oxidation by the non-steroidal anti-inflammatory drugs. Carcinogenesis, 1986, Volume: 7, Issue:4 Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Anti-Inflammatory Agents; Aspirin; Benzopyrenes; Dihydroxydihydrobenzopyrenes; Flufenamic Acid; Ibuprofen; Indomethacin; Liver; Male; Meclofenamic Acid; Mefenamic Acid; Oxidoreductases; Rats; Sulindac; Tolmetin	1986
Colitis caused by non-steroidal anti-inflammatory drugs. Postgraduate medical journal, 1986, Volume: 62, Issue:730 Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Female; Flufenamic Acid; Humans; Ibuprofen; Mefenamic Acid; Naproxen; Proctocolitis	1986
Arachidonic acid metabolites stimulate phosphatidylcholine secretion in primary cultures of type II pneumocytes. Biochimica et biophysica acta, 1985, Feb-08, Volume: 833, Issue:2 Topics: Animals; Arachidonic Acids; Catechols; Cells, Cultured; Dose-Response Relationship, Drug; Flufenamic Acid; Ibuprofen; In Vitro Techniques; Indomethacin; Lung; Male; Masoprocol; Naproxen; Phosphatidylcholines; Rats; Rats, Inbred Strains	1985
Diclofenac in the treatment of painful joints and traumatic tendinitis (including strains and sprains): a brief review. Seminars in arthritis and rheumatism, 1985, Volume: 15, Issue:2 Suppl 1 Topics: Diclofenac; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Joint Diseases; Ketoprofen; Naproxen; Pain; Sprains and Strains; Tendinopathy	1985
][A new method for screening of analgesics applied to heat induced inflammatory pain]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1974, Volume: 70, Issue:5 Topics: Aminopyrine; Analgesics; Animals; Aspirin; Burns; Drug Evaluation, Preclinical; Flufenamic Acid; Habituation, Psychophysiologic; Hot Temperature; Ibuprofen; Indomethacin; Inflammation; Mefenamic Acid; Phenylbutazone; Pyrroles; Rats	1974
Dysmenorrhoea: effective new approaches to a controversial problem. The Medical journal of Australia, 1980, Mar-22, Volume: 1, Issue:6 Topics: Cyclooxygenase Inhibitors; Dysmenorrhea; Female; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Mefenamic Acid; Naproxen	1980
Drug binding properties of glycosylated bovine serum albumin as measured by circular dichroism. Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:11 Topics: Binding Sites; Circular Dichroism; Flufenamic Acid; Glycosylation; Ibuprofen; Phenylbutazone; Protein Binding; Serum Albumin, Bovine; Warfarin	1994
Synthesis of the cholesteryl ester prodrugs cholesteryl ibuprofen and cholesteryl flufenamate and their formulation into phospholipid microemulsions. Journal of pharmaceutical sciences, 1994, Volume: 83, Issue:9 Topics: Biological Availability; Cholesterol Esters; Drug Carriers; Emulsions; Flufenamic Acid; Ibuprofen; Indicators and Reagents; Liposomes; Particle Size; Prodrugs; Solubility; Sterol Esterase	1994
A simple microassay for computing the hemolytic potency of drugs. BioTechniques, 1994, Volume: 17, Issue:6 Topics: Animals; Electronic Data Processing; Erythrocytes; Flufenamic Acid; Hemolysis; Ibuprofen; Indomethacin; Mice; Numerical Analysis, Computer-Assisted; Sensitivity and Specificity	1994
Drug binding properties of glycosylated human serum albumin as measured by fluorescence and circular dichroism. Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:1 Topics: Binding Sites; Circular Dichroism; Dansyl Compounds; Flufenamic Acid; Fluorescent Dyes; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Ibuprofen; Phenylbutazone; Proline; Protein Binding; Serum Albumin; Spectrometry, Fluorescence; Warfarin	1994
A study of the conditions of the supercritical fluid extraction in the analysis of selected anti-inflammatory drugs in plasma. Farmaco (Societa chimica italiana : 1989), 2002, Volume: 57, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Carbon Dioxide; Chromatography, High Pressure Liquid; Chromatography, Supercritical Fluid; Flufenamic Acid; Ibuprofen; Indomethacin; Methanol; Methylene Chloride; Solvents	2002
Determination of degradation pathways and kinetics of acyl glucuronides by NMR spectroscopy. Chemical research in toxicology, 2007, Volume: 20, Issue:6 Topics: Acylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile; Chromatography, Liquid; Cyclooxygenase Inhibitors; Diclofenac; Drug Stability; Flufenamic Acid; Glucuronides; Half-Life; Ibuprofen; Indomethacin; Kinetics; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mefenamic Acid; Molecular Structure; Rats; Rats, Sprague-Dawley; Stereoisomerism; Technology, Pharmaceutical; Tolmetin	2007
Assessing the removal of pharmaceuticals and personal care products in a full-scale activated sludge plant. Environmental science and pollution research international, 2012, Volume: 19, Issue:5 Topics: Adsorption; Diclofenac; Flufenamic Acid; Gas Chromatography-Mass Spectrometry; Hydroxyzine; Ibuprofen; Indapamide; Perfume; Pharmaceutical Preparations; Sewage; Solid Phase Extraction; Ultraviolet Rays; Waste Disposal, Fluid; Water Pollutants, Chemical	2012
Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3. PloS one, 2012, Volume: 7, Issue:8 Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anti-Inflammatory Agents, Non-Steroidal; Flufenamic Acid; Flurbiprofen; Hydroxyprostaglandin Dehydrogenases; Ibuprofen; Indomethacin; Meclofenamic Acid; Mefenamic Acid; Naproxen; Sulindac; Tolmetin	2012
Metabolism of non-steroidal anti-inflammatory drugs (NSAIDs) by Streptomyces griseolus CYP105A1 and its variants. Drug metabolism and pharmacokinetics, 2022, Volume: 45 Topics: Anti-Inflammatory Agents, Non-Steroidal; Bacterial Proteins; Cytochrome P-450 Enzyme System; Diclofenac; Flufenamic Acid; Humans; Ibuprofen; Meclofenamic Acid; Mefenamic Acid; Streptomyces	2022