ibuprofen and etodolac

ibuprofen has been researched along with etodolac in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19906 (15.38)18.7374
1990's3 (7.69)18.2507
2000's16 (41.03)29.6817
2010's11 (28.21)24.3611
2020's3 (7.69)2.80

Authors

AuthorsStudies
Asselin, AA; Conway, KM; Demerson, CA; Gavin, G; Guinosso, C; Humber, LG; Jensen, NP; Katz, AH; Mobilio, D; Shaw, CC1
Topliss, JG; Yoshida, F1
Cihlar, T; Ho, ES; Mulato, AS1
Beroza, P; Cai, D; Damodaran, K; Gomez, RF; Hsu, N; Keck, JG; Laborde, E; Lum, RT; Macke, TJ; Martin, G; Schow, SR; Simon, RJ; Villar, HO; Wick, MM1
Brozic, P; Gobec, S; Rizner, TL1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Anderluh, M; Brunskole, M; Gobec, S; Lanisnik Rizner, T; Stefane, B; Stojan, J; Zorko, K1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Kumar, M; Sinha, VR; Thareja, S1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Huang, S; Li, Y; Liu, W; Zhang, K; Zheng, X1
DeRose, EF; Duff, MR; Gabel, SA; Howell, EE; Krahn, JM; London, RE; Pedersen, LC1
Epstein, C; Kinberg-Calhoun, J; Mullane, JF; Sanda, M; Shand, DG1
Lanza, F; Lynn, M; Rack, MF; Sanda, M; Wolf, J1
Barkley, M; Kimball, ES; Neuman, RG; Weichman, BM; Wilson, BD; Wood, DD1
Crittenden, N; Fitzpatrick, F; McGee, J; McGuire, J1
Klicius, J; Martel, RR; Metcalf, G; Rona, GA1
Neustadt, DH1
Caruso, FS; Frenk, H; Lu, J; Mao, J; Mayer, DJ; Price, DD1
Wallace, JL1
Di Primeo, D; Genant, HK; Lynch, JM; Paulus, HE; Sanda, M; Schwartz, BA; Sharp, JT; Weissman, BN1
Bech, JN; Pedersen, EB; Svendsen, KB; Sørensen, TB1
Bagby, MD; Jackson, CR; Menke, ER; Tracy, TS1
Browning, RA; Burgess, FW1
Di Primeo, D; Genant, HK; Paulus, HE; Sanda, M; Sharp, JT; Weisman, MH; Weissman, BN1
Barner, JC; Busti, AJ; Lawson, KA; Motsko, SP; Rascati, KL; Wilson, JP; Worchel, J1
Hardikar, MS1
Akagi, Y; Aoyama, T; Nio, Y; Shimada, S1
da Silva, LM; de Miranda Silva, C; Donadi, EA; Lanchote, VL; Rocha, A; Tozatto, E1
Bassi, AP; Grossi de Oliveira, GA; Silva de Oliveira, JC1
Alshana, U; Hassan, M1
Farnezi Bassi, AP; Faverani, LP; Reis, EN; Silva, LD1
Akira, R; Bassi, APF; Chiba, F; de Lima Neto, TJ; Faverani, LP; Grossi-Oliveira, GA; Han, M; Miloro, M; Momesso, GAC; Polo, TOB; Rios, BR; Silva, WPP; Sumida, DH1

Reviews

4 review(s) available for ibuprofen and etodolac

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Distribution and expression of cyclooxygenase (COX) isoenzymes, their physiological roles, and the categorization of nonsteroidal anti-inflammatory drugs (NSAIDs).
    The American journal of medicine, 1999, Dec-13, Volume: 107, Issue:6A

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Controlled Clinical Trials as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Etodolac; Gene Expression; Humans; Ibuprofen; Indomethacin; Isoenzymes; Meloxicam; Membrane Proteins; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Thiazines; Thiazoles

1999
Chiral non-steroidal anti-inflammatory drugs--a review.
    Journal of the Indian Medical Association, 2008, Volume: 106, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Etodolac; Humans; Ibuprofen; Ketoprofen; Tromethamine

2008
Evidence-based review of clinical studies on pharmacology (non-anesthetic studies).
    Journal of endodontics, 2009, Volume: 35, Issue:8

    Topics: Acetaminophen; Administration, Oral; Analgesics; Anxiety; Dental Pulp Diseases; Dexamethasone; Drug Combinations; Etodolac; Evidence-Based Dentistry; Humans; Ibuprofen; Injections; Molar, Third; Music Therapy; Oxycodone; Pain, Postoperative; Randomized Controlled Trials as Topic; Root Canal Therapy; Tooth Extraction; Toothache; Treatment Outcome

2009

Trials

10 trial(s) available for ibuprofen and etodolac

ArticleYear
The effect of etodolac administration on renal function in patients with arthritis.
    Journal of clinical pharmacology, 1986, Volume: 26, Issue:4

    Topics: Acetates; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Blood Urea Nitrogen; Clinical Trials as Topic; Creatinine; Double-Blind Method; Etodolac; Humans; Ibuprofen; Kidney Function Tests; Middle Aged; Osteoarthritis; Sulindac

1986
An endoscopic comparison of the effects of etodolac, indomethacin, ibuprofen, naproxen, and placebo on the gastrointestinal mucosa.
    The Journal of rheumatology, 1987, Volume: 14, Issue:2

    Topics: Acetates; Adolescent; Adult; Endoscopy; Etodolac; Gastric Mucosa; Humans; Ibuprofen; Indomethacin; Intestinal Mucosa; Middle Aged; Naproxen; Placebos

1987
Double blind evaluation of the long-term effects of etodolac versus ibuprofen in patients with rheumatoid arthritis.
    The Journal of rheumatology. Supplement, 1997, Volume: 47

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Disease Progression; Double-Blind Method; Etodolac; Evaluation Studies as Topic; Female; Humans; Ibuprofen; Male; Middle Aged; Radiography

1997
Progression of radiographic joint erosion during low dose corticosteroid treatment of rheumatoid arthritis.
    The Journal of rheumatology, 2000, Volume: 27, Issue:7

    Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Arthrography; Disease Progression; Dose-Response Relationship, Drug; Etodolac; Female; Humans; Ibuprofen; Joints; Male; Middle Aged; Prednisone; Treatment Outcome

2000
A comparison of the effects of etodolac and ibuprofen on renal haemodynamics, tubular function, renin, vasopressin and urinary excretion of albumin and alpha-glutathione-S-transferase in healthy subjects: a placebo-controlled cross-over study.
    European journal of clinical pharmacology, 2000, Volume: 56, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arginine Vasopressin; Creatinine; Cross-Over Studies; Double-Blind Method; Etodolac; Female; Glomerular Filtration Rate; Glutathione Transferase; Hemodynamics; Humans; Ibuprofen; Kidney; Kidney Tubules; Male; Renin

2000
The effectiveness of prophylactic etodolac on postendodontic pain.
    Journal of endodontics, 2000, Volume: 26, Issue:12

    Topics: Acute Disease; Administration, Oral; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Chronic Disease; Dental Pulp Necrosis; Etodolac; Female; Follow-Up Studies; Humans; Ibuprofen; Male; Pain Measurement; Pain, Postoperative; Periapical Abscess; Periapical Diseases; Periapical Periodontitis; Placebos; Premedication; Pulpitis; Root Canal Therapy; Single-Blind Method; Treatment Outcome

2000
Patient retention and hand-wrist radiograph progression of rheumatoid arthritis during a 3-year prospective study that prohibited disease modifying antirheumatic drugs.
    The Journal of rheumatology, 2004, Volume: 31, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Disease Progression; Double-Blind Method; Etodolac; Female; Hand; Humans; Ibuprofen; Male; Middle Aged; Patient Compliance; Prospective Studies; Radiography; Wrist

2004
Comparative Assessment of the Effect of Ibuprofen and Etodolac on Edema, Trismus, and Pain in Lower Third Molar Surgery: A Randomized Clinical Trial.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2016, Volume: 74, Issue:8

    Topics: Adolescent; Cyclooxygenase 2 Inhibitors; Edema; Etodolac; Female; Humans; Ibuprofen; Male; Mandible; Molar, Third; Pain Management; Pain Measurement; Pain, Postoperative; Tooth Extraction; Tooth, Impacted; Treatment Outcome; Trismus; Young Adult

2016
The efficacy of etodolac and ibuprofen, regarding gender, on pain, edema and trismus after impacted lower third molar surgery: A randomized prospective clinical split-mouth study.
    Medicina oral, patologia oral y cirugia bucal, 2021, Mar-01, Volume: 26, Issue:2

    Topics: Adolescent; Adult; Edema; Etodolac; Female; Humans; Ibuprofen; Male; Molar, Third; Mouth; Pain, Postoperative; Prospective Studies; Tooth Extraction; Tooth, Impacted; Trismus; Young Adult

2021
A triple-blind randomized clinical trial of different associations between dexamethasone and non-steroids anti-inflammatories for preemptive action in third molar extractions.
    Scientific reports, 2021, 12-27, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Drug Therapy, Combination; Etodolac; Female; Glucocorticoids; Humans; Ibuprofen; Ketorolac; Male; Molar, Third; Phenylpropionates; Prospective Studies; Tooth Extraction; Young Adult

2021

Other Studies

25 other study(ies) available for ibuprofen and etodolac

ArticleYear
Synthesis and analgesic activity of pemedolac (cis-1-ethyl-1,3,4,9-tetrahydro-4-(phenylmethyl)pyrano[3,4-b]ind ole-1- acetic acid).
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:6

    Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Indoleacetic Acids; Male; Mice; Molecular Conformation; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1988
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 295, Issue:1

    Topics: Adenine; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Biological Transport; Carrier Proteins; Humans; Kidney; Organophosphonates; Structure-Activity Relationship

2000
Novel cyclooxygenase-1 inhibitors discovered using affinity fingerprints.
    Journal of medicinal chemistry, 2004, Sep-23, Volume: 47, Issue:20

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Combinatorial Chemistry Techniques; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Design; Drug Evaluation, Preclinical; Ibuprofen; Inhibitory Concentration 50; Isoenzymes; Models, Molecular; Models, Theoretical; Molecular Structure; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Quantitative Structure-Activity Relationship

2004
Nonsteroidal anti-inflammatory drugs and their analogues as inhibitors of aldo-keto reductase AKR1C3: new lead compounds for the development of anticancer agents.
    Bioorganic & medicinal chemistry letters, 2005, Dec-01, Volume: 15, Issue:23

    Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Drug Design; Enzyme Inhibitors; Humans; Hydroxyprostaglandin Dehydrogenases; Molecular Structure; Tumor Cells, Cultured

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Towards the first inhibitors of trihydroxynaphthalene reductase from Curvularia lunata: synthesis of artificial substrate, homology modelling and initial screening.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Amino Acid Sequence; Ascomycota; Benzopyrans; Enzyme Inhibitors; Fungal Proteins; Melanins; Models, Molecular; Molecular Sequence Data; Oxidoreductases Acting on CH-CH Group Donors; Recombinant Proteins; Structural Homology, Protein; Substrate Specificity

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
    European journal of medicinal chemistry, 2012, Volume: 53

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship

2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Synergistic effect of tolfenamic acid and glycyrrhizic acid on TPA-induced skin inflammation in mice.
    MedChemComm, 2019, Oct-01, Volume: 10, Issue:10

    Topics:

2019
The Structural Basis for Nonsteroidal Anti-Inflammatory Drug Inhibition of Human Dihydrofolate Reductase.
    Journal of medicinal chemistry, 2020, 08-13, Volume: 63, Issue:15

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Crystallography, X-Ray; Drug Design; Folic Acid; Folic Acid Antagonists; Humans; Models, Molecular; Tetrahydrofolate Dehydrogenase

2020
Inhibition of prostaglandin biosynthesis by etodolac. I. Selective activities in arthritis.
    Agents and actions, 1987, Volume: 21, Issue:1-2

    Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cartilage; Cattle; Cells, Cultured; Dinoprostone; Etodolac; Female; Ibuprofen; Indomethacin; Macrophages; Male; Mice; Mice, Inbred C57BL; Piroxicam; Prostaglandin Antagonists; Prostaglandins; Prostaglandins E; Rats; Rats, Inbred Strains; Synovial Fluid

1987
Cell damage unmasks 15-lipoxygenase activity in human neutrophils.
    The Journal of biological chemistry, 1985, Jul-15, Volume: 260, Issue:14

    Topics: Acetates; Arachidonate Lipoxygenases; Aspirin; Dose-Response Relationship, Drug; Etodolac; Fluorometry; Flurbiprofen; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; L-Lactate Dehydrogenase; Lipoxygenase; Naproxen; Neutrophils; Phenylbutazone

1985
Comparative effects of long term treatment with etodolac, naproxen and ibuprofen on articular and bone changes associated with adjuvant arthritis in rats.
    Agents and actions, 1984, Volume: 15, Issue:3-4

    Topics: Acetates; Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Body Weight; Bone and Bones; Cartilage, Articular; Etodolac; Ibuprofen; Naproxen; Radiography; Rats; Rats, Inbred Strains; Time Factors

1984
Effects of the combined oral administration of NSAIDs and dextromethorphan on behavioral symptoms indicative of arthritic pain in rats.
    Pain, 1996, Volume: 68, Issue:1

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Behavior, Animal; Dextromethorphan; Diclofenac; Drug Interactions; Drug Therapy, Combination; Etodolac; Ibuprofen; Injections, Intraperitoneal; Male; Naproxen; Pain; Piroxicam; Rats; Rats, Sprague-Dawley

1996
Nonsteroidal anti-inflammatory drugs for perioperative pain control.
    Medicine and health, Rhode Island, 2001, Volume: 84, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Etodolac; Humans; Ibuprofen; Indomethacin; Ketorolac; Lactones; Nabumetone; Naproxen; Pain, Postoperative; Piroxicam; Pyrazoles; Sulfonamides; Sulfones; Time Factors

2001
Temporal relationship between use of NSAIDs, including selective COX-2 inhibitors, and cardiovascular risk.
    Drug safety, 2006, Volume: 29, Issue:7

    Topics: Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Celecoxib; Cohort Studies; Cyclooxygenase 2 Inhibitors; Etodolac; Female; Humans; Ibuprofen; Lactones; Male; Middle Aged; Naproxen; Pyrazoles; Sulfonamides; Sulfones; Time Factors; United States; Veterans

2006
Influence of nonsteroidal anti-inflammatory drugs on the antiplatelet effects of aspirin in rats.
    Biological & pharmaceutical bulletin, 2011, Volume: 34, Issue:2

    Topics: Acetylation; Adenosine Diphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Collagen; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Drug Interactions; Etodolac; Ibuprofen; Male; Phenylpropionates; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thromboxane B2

2011
Enantioselective analysis of etodolac in human plasma by LC-MS/MS: Application to clinical pharmacokinetics.
    Journal of pharmaceutical and biomedical analysis, 2016, Feb-20, Volume: 120

    Topics: Acetates; Adult; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, Liquid; Etodolac; Hexanes; Humans; Ibuprofen; Male; Plasma; Stereoisomerism; Tandem Mass Spectrometry

2016
Switchable-hydrophilicity solvent liquid-liquid microextraction of non-steroidal anti-inflammatory drugs from biological fluids prior to HPLC-DAD determination.
    Journal of pharmaceutical and biomedical analysis, 2019, Sep-10, Volume: 174

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Centrifugation; Chromatography, High Pressure Liquid; Etodolac; Flurbiprofen; Humans; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Ketoprofen; Linear Models; Liquid Phase Microextraction; Milk, Human; Organic Chemicals; Reproducibility of Results; Saliva; Sodium Hydroxide; Solvents

2019