ibuprofen and enalapril

ibuprofen has been researched along with enalapril in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.55)18.7374
1990's2 (9.09)18.2507
2000's9 (40.91)29.6817
2010's9 (40.91)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Kobayashi, Y; Kohyama, N; Ohbayashi, M; Ohshiro, N; Tsuchiya, A; Yamamoto, T1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Avdeef, A; Tam, KY1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Arosio, E; Degan, M; Lechi, A; Minuz, P; Pancera, P; Priante, F; Ribul, M1
Arosio, E; Capuzzo, MG; Corsato, M; Dalla Riva, A; Degan, M; Lechi, A; Lechi, C; Minuz, P; Velo, GP1
Hancock, EW1
Brodskaia, SA; Ivanov, SN; Savenkov, MP1
Aalto-Setälä, V1
Huque, SS; Khatun, S; Rahman, MH1
Krawczeski, CD; Kwiatkowski, DM; Montez-Rath, ME; Sutherland, SM; Uber, AM1
Breitkreutz, J; Kokott, M; Lura, A; Wiedey, R1

Reviews

1 review(s) available for ibuprofen and enalapril

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for ibuprofen and enalapril

ArticleYear
Prostaglandin I2 and thromboxane B2 biosynthesis and haemodynamic effects of lisinopril.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1991, Volume: 9, Issue:6

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Compliance; Double-Blind Method; Enalapril; Epoprostenol; Female; Hemodynamics; Humans; Hypertension; Ibuprofen; Lisinopril; Male; Middle Aged; Thromboxane B2; Vascular Resistance

1991
[Antihypertensive effect of enalapril and lisinopril administered in combination with nonsteroid anti-inflammatory agents].
    Terapevticheskii arkhiv, 2001, Volume: 73, Issue:9

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Drug Antagonism; Enalapril; Female; Humans; Hypertension; Ibuprofen; Indomethacin; Lisinopril; Male; Middle Aged; Osteochondritis

2001

Other Studies

19 other study(ies) available for ibuprofen and enalapril

ArticleYear
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Renal transport of organic compounds mediated by mouse organic anion transporter 3 (mOat3): further substrate specificity of mOat3.
    Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:5

    Topics: Allopurinol; Animals; Biological Transport; Dose-Response Relationship, Drug; Female; Kidney; Male; Mice; Oocytes; Organic Anion Transporters, Sodium-Independent; Substrate Specificity; Xenopus laevis

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Antihypertensive activity of enalapril. Effect of ibuprofen and different salt intakes.
    Journal of clinical hypertension, 1987, Volume: 3, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Enalapril; Humans; Hypertension; Ibuprofen; Kallikreins; Male; Middle Aged; Renin; Sodium, Dietary

1987
Normal ECG or peaked T waves?
    Hospital practice (1995), 1998, May-15, Volume: 33, Issue:5

    Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Diabetes Mellitus, Type 1; Diuretics; Electrocardiography; Enalapril; Female; Humans; Hyperkalemia; Ibuprofen; Middle Aged; Spironolactone

1998
The impact of generic substitution on price competition in Finland.
    The European journal of health economics : HEPAC : health economics in prevention and care, 2008, Volume: 9, Issue:2

    Topics: Commerce; Drug Costs; Drug Industry; Drug Prescriptions; Drugs, Generic; Economic Competition; Enalapril; Finland; Ibuprofen; Models, Economic; Ranitidine

2008
Bartter Syndrome with Normal Aldosterone Level: An Unusual Presentation.
    Mymensingh medical journal : MMJ, 2016, Volume: 25, Issue:2

    Topics: Aldosterone; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Bangladesh; Bartter Syndrome; Dietary Supplements; Enalapril; Female; Fluid Therapy; Humans; Ibuprofen; Infant; Potassium; Treatment Outcome

2016
Nephrotoxin exposure and acute kidney injury in critically ill children undergoing congenital cardiac surgery.
    Pediatric nephrology (Berlin, Germany), 2018, Volume: 33, Issue:11

    Topics: Acute Kidney Injury; Adolescent; Aspirin; Cardiac Surgical Procedures; Child; Child, Preschool; Critical Illness; Enalapril; Female; Heart Defects, Congenital; Humans; Ibuprofen; Infant; Ketorolac; Male; Piperacillin, Tazobactam Drug Combination; Postoperative Complications; Retrospective Studies; Vancomycin

2018
Evaluation of two novel co-processed excipients for direct compression of orodispersible tablets and mini-tablets.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2021, Volume: 168

    Topics: Acetaminophen; Chemistry, Pharmaceutical; Drug Compounding; Enalapril; Excipients; Ibuprofen; Mannitol; Tablets; Tensile Strength

2021