ibuprofen has been researched along with diflunisal in 52 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 20 (38.46) | 18.7374 |
1990's | 4 (7.69) | 18.2507 |
2000's | 12 (23.08) | 29.6817 |
2010's | 14 (26.92) | 24.3611 |
2020's | 2 (3.85) | 2.80 |
Authors | Studies |
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Hannah, J; Holtz, WJ; Houser, RA; Jones, H; Kelly, KW; Matzuk, AR; Ruyle, WV; Sarett, LH; Shen, TY; Witzel, BE | 1 |
Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S | 1 |
Strassburg, CP; Tukey, RH | 1 |
Topliss, JG; Yoshida, F | 1 |
Cihlar, T; Ho, ES; Mulato, AS | 1 |
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
Beroza, P; Cai, D; Damodaran, K; Gomez, RF; Hsu, N; Keck, JG; Laborde, E; Lum, RT; Macke, TJ; Martin, G; Schow, SR; Simon, RJ; Villar, HO; Wick, MM | 1 |
Chang, TK; Ensom, MH; Kiang, TK | 1 |
Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Abdellatif, KR; Chowdhury, MA; Das, D; Dong, Y; Knaus, EE; Suresh, MR; Velázquez, CA; Yu, G | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P | 1 |
Kumar, M; Sinha, VR; Thareja, S | 1 |
Bellman, K; Knegtel, RM; Settimo, L | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
Ahmed, R; Boulton, S; Cheng, X; Melacini, G; Selvaratnam, R; Van, K | 1 |
DeRose, EF; Duff, MR; Gabel, SA; Howell, EE; Krahn, JM; London, RE; Pedersen, LC | 1 |
Altman, RA; Borel, T; Davis, I; de Azambuja, F; Johnson, D; Liu, A; Sorrentino, JP; Udokwu, C; Yang, Y | 1 |
Keet, JG | 1 |
Garg, A | 1 |
Bergamo, RR; Cominelli, F; Kopple, JD; Zipser, RD | 1 |
Carroll, MJ; Giles, AD; Hill, CM; Pickvance, N | 1 |
Ciancio, SG | 1 |
Altman, R | 1 |
Bennett, RM | 1 |
Seymour, RA | 1 |
Kunitake, LM; Pallasch, TJ | 1 |
Hudyma, EO; Kollenberg, LO; Robbins, JM | 1 |
Cooper, SA | 1 |
Fasching, U | 1 |
Altman, RD | 1 |
Bhalla, AK; Simon, LS | 1 |
Cronberg, S; Söderberg, I; Wallmark, E | 1 |
Amadio, P | 1 |
Court, H; Volans, GN | 1 |
Deuben, RR | 1 |
Ferry, DG; Gibbins, BL; Grennan, DM; Hall, SM; Lum, J; Myers, DB; Palmer, DG | 1 |
Gilbart, M; Ogilvie-Harris, DJ | 1 |
Arroyo, JF; Day, RO; Nguyen, T; Walker, JS | 1 |
Davey, J | 1 |
Koç, FE; Senel, M | 1 |
Ascenzi, P; Coletta, M; di Masi, A; Fanali, G; Fasano, M; Gioia, M; Leboffe, L; Trezza, V | 1 |
Biles, CL; Broge, M; Cluck, T; Dahal, S; Dalmont, K; Gurung, T; Howard, A; Konsure, H; Poudyal, S; Rowsey, T; Shrestha, S | 1 |
7 review(s) available for ibuprofen and diflunisal
Article | Year |
---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
New peripherally-acting oral analgesic agents.
Topics: Administration, Oral; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Diflunisal; Humans; Ibuprofen; Indoprofen; Naproxen; Pain; Pain, Postoperative; Tolmetin | 1983 |
Non-steroidal anti-inflammatory drugs (NSAID'S) as analgesics in dentistry - a review.
Topics: Analgesics; Anti-Inflammatory Agents; Aspirin; Dental Care; Diflunisal; Humans; Ibuprofen; Indomethacin; Ketoprofen; Oxyphenbutazone; Pain, Postoperative; Phenylbutazone | 1983 |
Review of ibuprofen for osteoarthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Meclofenamic Acid; Naproxen; Osteoarthritis; Phenylbutazone; Sulindac; Tolmetin | 1984 |
Treatment modalities for soft tissue injuries of the ankle: a critical review.
Topics: Age Factors; Ankle Injuries; Anti-Inflammatory Agents, Non-Steroidal; Casts, Surgical; Confounding Factors, Epidemiologic; Cryotherapy; Diflunisal; Double-Blind Method; Humans; Ibuprofen; Peptide Hydrolases; Physical Therapy Modalities; Placebos; Prospective Studies; Racial Groups; Randomized Controlled Trials as Topic; Research Design; Sample Size; Sex Factors; Soft Tissue Injuries; Ultrasonic Therapy | 1995 |
9 trial(s) available for ibuprofen and diflunisal
Article | Year |
---|---|
A comparative clinical trial of diflunisal and ibuprofen in the control of pain in osteoarthritis.
Topics: Clinical Trials as Topic; Diflunisal; Double-Blind Method; Female; Hip Joint; Humans; Ibuprofen; Knee Joint; Male; Middle Aged; Osteoarthritis; Pain; Salicylates | 1979 |
Ibuprofen given pre- and post-operatively for the relief of pain.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Codeine; Diflunisal; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Male; Middle Aged; Molar, Third; Pain, Postoperative; Premedication; Tooth Extraction | 1987 |
International experiences with diclofenac in osteoarthritis.
Topics: Aspirin; Clinical Trials as Topic; Diclofenac; Diflunisal; Double-Blind Method; Gastrointestinal Diseases; Humans; Ibuprofen; Indomethacin; Naproxen; Osteoarthritis; Random Allocation; Sulindac | 1986 |
A 12-week, double-blind, multicenter study comparing diflunisal twice daily and ibuprofen four times daily in the treatment of rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Drug Administration Schedule; Drug Tolerance; Humans; Ibuprofen; Middle Aged; Random Allocation; Salicylates; Time Factors | 1986 |
New peripherally-acting oral analgesic agents.
Topics: Administration, Oral; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Diflunisal; Humans; Ibuprofen; Indoprofen; Naproxen; Pain; Pain, Postoperative; Tolmetin | 1983 |
[Comparison of the effects of diflunisal, ibuprofen and placebo in chronic polyarthritis].
Topics: Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Humans; Ibuprofen; Middle Aged; Salicylates | 1983 |
Review of ibuprofen for osteoarthritis.
Topics: Acetaminophen; Anti-Inflammatory Agents; Aspirin; Clinical Trials as Topic; Diflunisal; Drug Tolerance; Fenoprofen; Humans; Ibuprofen; Indomethacin; Meclofenamic Acid; Naproxen; Osteoarthritis; Phenylbutazone; Sulindac; Tolmetin | 1984 |
Ibuprofen and diflunisal in rheumatoid arthritis: a double-blind comparative trial.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Female; Humans; Ibuprofen; Lymphocytes; Male; Random Allocation; Salicylates | 1981 |
Analgesic efficacy of non-steroidal anti-inflammatory drugs in experimental pain in humans.
Topics: Adult; Analgesia; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Diflunisal; Humans; Ibuprofen; Pain; Pain Measurement; Pain Threshold | 1993 |
38 other study(ies) available for ibuprofen and diflunisal
Article | Year |
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Novel analgesic-antiinflammatory salicylates.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry; Dogs; Rats; Salicylates; Structure-Activity Relationship | 1978 |
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes.
Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1.
Topics: Adenine; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Biological Transport; Carrier Proteins; Humans; Kidney; Organophosphonates; Structure-Activity Relationship | 2000 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Novel cyclooxygenase-1 inhibitors discovered using affinity fingerprints.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Combinatorial Chemistry Techniques; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Design; Drug Evaluation, Preclinical; Ibuprofen; Inhibitory Concentration 50; Isoenzymes; Models, Molecular; Models, Theoretical; Molecular Structure; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Quantitative Structure-Activity Relationship | 2004 |
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Synthesis and biological evaluation of salicylic acid and N-acetyl-2-carboxybenzenesulfonamide regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory ac
Topics: Aspirin; Cyclooxygenase 2 Inhibitors; Humans; Isomerism; Lipoxygenase Inhibitors; Pyridones; Salicylates; Sulfonamides | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence | 2010 |
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship | 2012 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Mechanisms of Specific versus Nonspecific Interactions of Aggregation-Prone Inhibitors and Attenuators.
Topics: Binding Sites; Buffers; Dose-Response Relationship, Drug; Drug Discovery; False Positive Reactions; Humans; Light; Magnetic Resonance Spectroscopy; Octoxynol; Protein Kinase Inhibitors; Scattering, Radiation; Serum Albumin, Human; Spectrometry, Mass, Electrospray Ionization; Surface Plasmon Resonance; Thermodynamics | 2019 |
The Structural Basis for Nonsteroidal Anti-Inflammatory Drug Inhibition of Human Dihydrofolate Reductase.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Crystallography, X-Ray; Drug Design; Folic Acid; Folic Acid Antagonists; Humans; Models, Molecular; Tetrahydrofolate Dehydrogenase | 2020 |
Diflunisal Derivatives as Modulators of ACMS Decarboxylase Targeting the Tryptophan-Kynurenine Pathway.
Topics: Bacterial Proteins; Binding Sites; Biosynthetic Pathways; Carboxy-Lyases; Catalytic Domain; Crystallography, X-Ray; Diflunisal; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kynurenine; Molecular Docking Simulation; NAD; Pseudomonas fluorescens; Structure-Activity Relationship; Tryptophan | 2021 |
Pharmacological agents used in implant dentistry.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Dental Implantation, Endosseous; Diflunisal; Humans; Ibuprofen; Naproxen; Pain; Steroids | 1992 |
Comparative acute effects of aspirin, diflunisal, ibuprofen and indomethacin on renal function in healthy man.
Topics: Adult; Aspirin; Diflunisal; Humans; Ibuprofen; Indomethacin; Kidney; Kidney Function Tests; Male | 1989 |
Drugs in dentistry. NSAIDs.
Topics: Anti-Inflammatory Agents; Dental Care; Diflunisal; Humans; Ibuprofen; Meclofenamic Acid; Mefenamic Acid; Suprofen | 1986 |
Prescribing analgesics.
Topics: Acetaminophen; Aged; Analgesics; Anticoagulants; Aspirin; Child; Codeine; Diflunisal; Drug Hypersensitivity; Female; Humans; Ibuprofen; Mefenamic Acid; Meperidine; Pain, Postoperative; Pentazocine; Pregnancy; Tooth | 1985 |
Nonsteroidal anti-inflammatory analgesics.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diflunisal; Drug Interactions; Humans; Ibuprofen; Tolmetin | 1985 |
Nonsteroidal anti-inflammatory agents. A review of the literature.
Topics: Absorption; Anti-Inflammatory Agents; Aspirin; Diflunisal; Drug Interactions; Female; Fenoprofen; Half-Life; Humans; Ibuprofen; Indomethacin; Kinetics; Meclofenamic Acid; Naproxen; Phenylbutazone; Piroxicam; Pregnancy; Thiazines; Tolmetin | 1985 |
A clinical evaluation of the antiarthritic agents.
Topics: Anti-Inflammatory Agents; Antimalarials; Arthritis; Aspirin; Diflunisal; Fenoprofen; Glucocorticoids; Gold; Humans; Ibuprofen; Immunosuppressive Agents; Indomethacin; Naproxen; ortho-Aminobenzoates; Penicillamine; Piroxicam; Prostaglandin Antagonists; Salicylates; Sulindac; Thiazines; Tolmetin | 1984 |
Effect on platelet aggregation of oral administration of 10 non-steroidal analgesics to humans.
Topics: Acetaminophen; Adult; Analgesics; Aspirin; Diclofenac; Diflunisal; Epinephrine; Female; Humans; Ibuprofen; Indomethacin; Male; Middle Aged; Naproxen; Oxyphenbutazone; Piroxicam; Platelet Aggregation; Thiazines; Time Factors | 1984 |
Peripherally acting analgesics.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Aspirin; Diflunisal; Fenoprofen; Humans; Ibuprofen; Mefenamic Acid; Naproxen; Pain; Primary Health Care | 1984 |
Poisoning after overdose with non-steroidal anti-inflammatory drugs.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Child, Preschool; Diflunisal; Female; Fenoprofen; Feprazone; Humans; Ibuprofen; Indomethacin; Ketoprofen; London; Male; Mefenamic Acid; Naproxen; Oxyphenbutazone; Phenylbutazone; Piroxicam; Thiazines; Tolmetin | 1984 |
Nonopioid analgesics for patients with dental pain.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dental Care; Diflunisal; Humans; Ibuprofen; Kinetics; Mefenamic Acid | 1984 |
The advantages and limitations of the analgesics available for control of postoperative pain after a dental procedure.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Codeine; Cyclooxygenase 2 Inhibitors; Dental Care; Diclofenac; Diflunisal; Drug Combinations; Humans; Ibuprofen; Narcotics; Oral Surgical Procedures; Pain, Postoperative; Tramadol | 2013 |
Solubility enhancement of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) using polypolypropylene oxide core PAMAM dendrimers.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Dendrimers; Diflunisal; Drug Delivery Systems; Ibuprofen; Ketoprofen; Polymers; Propylene Glycols; Solubility; Temperature | 2013 |
Ligand binding to the FA3-FA4 cleft inhibits the esterase-like activity of human serum albumin.
Topics: Diazepam; Diflunisal; Esterases; Esters; Humans; Hydrogen-Ion Concentration; Hydrolysis; Ibuprofen; Models, Molecular; Propofol; Serum Albumin; Tyrosine | 2015 |
Nonsteroidal Anti-inflammatory Drugs (NSAIDS) Inhibit the Growth and Reproduction of Chaetomium globosum and Other Fungi Associated with Water-Damaged Buildings.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Aspergillus; Aspirin; Cell Proliferation; Chaetomium; Diclofenac; Diflunisal; Fusarium; Germination; Humans; Ibuprofen; Lung Diseases, Fungal; Microbial Sensitivity Tests; Mycoses; Stachybotrys | 2017 |