ibuprofen and clonidine

ibuprofen has been researched along with clonidine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.33)18.7374
1990's0 (0.00)18.2507
2000's10 (41.67)29.6817
2010's12 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Topliss, JG; Yoshida, F1
Faassen, F; Spanings, H; Vogel, G; Vromans, H1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Akamatsu, M1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Barnaby, O; Bourin, C; Bristow, LJ; Bronson, J; Chen, P; Dzierba, C; Easton, A; Guernon, J; Herrington, J; Knox, RJ; Luo, G; Matchett, M; McClure, A; Meanwell, NA; Mosure, K; Newton, A; Ng, A; Olson, R; Parker, D; Pieschl, R; Rajamani, R; Sivarao, DV; Soars, MG; Thompson, LA; Wu, YJ1
Culnane, M; Dubner, R; Gracely, RH; Max, MB; Schafer, SC1
Kim, KH; Park, SC1
Alencar, FG; Becker, A; Viana, PG; Zamperini, C1
Duma, SN1
Donato, AA; Hao, D; Olugbodi, A; Udechukwu, N1
Friedman, BW; Gallagher, EJ; Irizarry, E; Jones, MP; Pearlman, S; Shah, PD; Solorzano, C; Wollowitz, A; Zias, E1

Reviews

1 review(s) available for ibuprofen and clonidine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

5 trial(s) available for ibuprofen and clonidine

ArticleYear
Association of pain relief with drug side effects in postherpetic neuralgia: a single-dose study of clonidine, codeine, ibuprofen, and placebo.
    Clinical pharmacology and therapeutics, 1988, Volume: 43, Issue:4

    Topics: Aged; Aged, 80 and over; Clinical Trials as Topic; Clonidine; Codeine; Double-Blind Method; Female; Herpes Zoster; Humans; Ibuprofen; Male; Middle Aged; Neuralgia; Pain Measurement; Random Allocation

1988
Effect of adding cervical facet joint injections in a multimodal treatment program for long-standing cervical myofascial pain syndrome with referral pain patterns of cervical facet joint syndrome.
    Journal of anesthesia, 2012, Volume: 26, Issue:5

    Topics: Acetaminophen; Anesthetics, General; Chronic Pain; Clonidine; Codeine; Combined Modality Therapy; Double-Blind Method; Exercise Therapy; Female; Follow-Up Studies; Humans; Ibuprofen; Injections; Male; Middle Aged; Myofascial Pain Syndromes; Neck Pain; Pain Measurement; Prospective Studies; Zygapophyseal Joint

2012
Patient education and self-care for the management of jaw pain upon awakening: a randomized controlled clinical trial comparing the effectiveness of adding pharmacologic treatment with cyclobenzaprine or tizanidine.
    Journal of oral & facial pain and headache, 2014,Spring, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Aged; Amitriptyline; Analgesics, Non-Narcotic; Clonidine; Double-Blind Method; Facial Pain; Female; Humans; Ibuprofen; Male; Middle Aged; Muscle Relaxants, Central; Pain Measurement; Patient Education as Topic; Placebos; Self Care; Severity of Illness Index; Sleep; Temporomandibular Joint Dysfunction Syndrome; Treatment Outcome; Young Adult

2014
[A role of treatment of autonomic syndrome in patients with tension-type headache].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2015, Volume: 115, Issue:2

    Topics: Administration, Oral; Adult; Analgesics, Non-Narcotic; Autonomic Nervous System; Autonomic Nervous System Diseases; Clonidine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Ibuprofen; Pain Measurement; Parasympatholytics; Surveys and Questionnaires; Syndrome; Tension-Type Headache; Treatment Outcome

2015
A Randomized, Placebo-Controlled Trial of Ibuprofen Plus Metaxalone, Tizanidine, or Baclofen for Acute Low Back Pain.
    Annals of emergency medicine, 2019, Volume: 74, Issue:4

    Topics: Acute Pain; Adult; Analgesics, Non-Narcotic; Baclofen; Clonidine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Low Back Pain; Male; Muscle Relaxants, Central; Oxazolidinones; Treatment Outcome

2019

Other Studies

18 other study(ies) available for ibuprofen and clonidine

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs.
    International journal of pharmaceutics, 2003, Sep-16, Volume: 263, Issue:1-2

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caco-2 Cells; Cell Membrane Permeability; Heterocyclic Compounds; Humans; Protein Transport

2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Discovery of non-zwitterionic aryl sulfonamides as Na
    Bioorganic & medicinal chemistry, 2017, 10-15, Volume: 25, Issue:20

    Topics: Administration, Oral; Animals; Chronic Pain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Freund's Adjuvant; HEK293 Cells; Humans; Inflammation; Male; Mice; Models, Biological; Molecular Structure; NAV1.7 Voltage-Gated Sodium Channel; Neurons; Nociception; Structure-Activity Relationship; Sulfonamides

2017
Trauma-induced adiposis dolorosa (Dercum's disease).
    BMJ case reports, 2018, Mar-28, Volume: 2018

    Topics: Accidents, Traffic; Adipose Tissue; Adiposis Dolorosa; Adult; Amitriptyline; Analgesics, Non-Narcotic; Angiomyolipoma; Baclofen; Chronic Pain; Clonidine; Diagnosis, Differential; Humans; Ibuprofen; Male; Muscle Relaxants, Central; Tomography, X-Ray Computed; Upper Extremity

2018