ibuprofen has been researched along with chf 5074 in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cenacchi, V; Facchinetti, F; Hutter-Paier, B; Imbimbo, BP; Lanzillotta, A; Pizzi, M; Villetti, G; Volta, R; Windisch, M | 1 |
| Baltrons, MA; Carriba, P; Galea, E; García, A; Lichtenstein, MP; Peterson, JR; Wojciak-Stothard, B | 1 |
| Baiguera, C; Benarese, M; Branca, C; Hutter-Paier, B; Imbimbo, BP; Lanzillotta, A; Pizzi, M; Sarnico, I; Spano, P; Windisch, M | 1 |
| Bellucci, A; Benarese, M; Branca, C; Faggi, L; Imbimbo, BP; Lanzillotta, A; Mota, M; Parrella, E; Pizzi, M; Porrini, V; Sarnico, I; Spano, P | 1 |
4 other study(ies) available for ibuprofen and chf 5074
| Article | Year |
|---|---|
CHF5074, a novel gamma-secretase modulator, attenuates brain beta-amyloid pathology and learning deficit in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Brain; Cyclopropanes; Flurbiprofen; Humans; Ibuprofen; Learning Disabilities; Memory; Mice; Mice, Transgenic; Microglia; Mutation; Peptide Fragments; Plaque, Amyloid | 2009 |
Secretase-independent and RhoGTPase/PAK/ERK-dependent regulation of cytoskeleton dynamics in astrocytes by NSAIDs and derivatives.
Topics: Amyloid Precursor Protein Secretases; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Blotting, Western; Cells, Cultured; Cerebellum; Cerebral Cortex; Cyclooxygenase 2; Cyclopropanes; Cytoskeleton; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Flurbiprofen; Ibuprofen; Immunohistochemistry; Rats; Rats, Sprague-Dawley; rho GTP-Binding Proteins; Signal Transduction | 2010 |
The γ-secretase modulator CHF5074 reduces the accumulation of native hyperphosphorylated tau in a transgenic mouse model of Alzheimer's disease.
Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Cells, Cultured; Cyclooxygenase Inhibitors; Cyclopropanes; Diet; Disease Models, Animal; Flurbiprofen; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Ibuprofen; Mice; Mice, Transgenic; Neurons; Peptide Fragments; Phosphorylation; Signal Transduction; tau Proteins | 2011 |
Neuroprotective and Anti-Apoptotic Effects of CSP-1103 in Primary Cortical Neurons Exposed to Oxygen and Glucose Deprivation.
Topics: Animals; Apoptosis; Caspase 3; Cell Nucleus; Cerebral Cortex; Cyclopropanes; Cytochromes c; Enzyme Activation; Flurbiprofen; Glucose; Glycogen Synthase Kinase 3 beta; Ibuprofen; Mice, Inbred C57BL; Necrosis; Neurons; Neuroprotective Agents; Oxygen; p38 Mitogen-Activated Protein Kinases; Transcription Factor RelA | 2017 |