ibuprofen and chf 5074

ibuprofen has been researched along with chf 5074 in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cenacchi, V; Facchinetti, F; Hutter-Paier, B; Imbimbo, BP; Lanzillotta, A; Pizzi, M; Villetti, G; Volta, R; Windisch, M1
Baltrons, MA; Carriba, P; Galea, E; García, A; Lichtenstein, MP; Peterson, JR; Wojciak-Stothard, B1
Baiguera, C; Benarese, M; Branca, C; Hutter-Paier, B; Imbimbo, BP; Lanzillotta, A; Pizzi, M; Sarnico, I; Spano, P; Windisch, M1
Bellucci, A; Benarese, M; Branca, C; Faggi, L; Imbimbo, BP; Lanzillotta, A; Mota, M; Parrella, E; Pizzi, M; Porrini, V; Sarnico, I; Spano, P1

Other Studies

4 other study(ies) available for ibuprofen and chf 5074

ArticleYear
CHF5074, a novel gamma-secretase modulator, attenuates brain beta-amyloid pathology and learning deficit in a mouse model of Alzheimer's disease.
    British journal of pharmacology, 2009, Volume: 156, Issue:6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Brain; Cyclopropanes; Flurbiprofen; Humans; Ibuprofen; Learning Disabilities; Memory; Mice; Mice, Transgenic; Microglia; Mutation; Peptide Fragments; Plaque, Amyloid

2009
Secretase-independent and RhoGTPase/PAK/ERK-dependent regulation of cytoskeleton dynamics in astrocytes by NSAIDs and derivatives.
    Journal of Alzheimer's disease : JAD, 2010, Volume: 22, Issue:4

    Topics: Amyloid Precursor Protein Secretases; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Blotting, Western; Cells, Cultured; Cerebellum; Cerebral Cortex; Cyclooxygenase 2; Cyclopropanes; Cytoskeleton; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Flurbiprofen; Ibuprofen; Immunohistochemistry; Rats; Rats, Sprague-Dawley; rho GTP-Binding Proteins; Signal Transduction

2010
The γ-secretase modulator CHF5074 reduces the accumulation of native hyperphosphorylated tau in a transgenic mouse model of Alzheimer's disease.
    Journal of molecular neuroscience : MN, 2011, Volume: 45, Issue:1

    Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Cells, Cultured; Cyclooxygenase Inhibitors; Cyclopropanes; Diet; Disease Models, Animal; Flurbiprofen; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Ibuprofen; Mice; Mice, Transgenic; Neurons; Peptide Fragments; Phosphorylation; Signal Transduction; tau Proteins

2011
Neuroprotective and Anti-Apoptotic Effects of CSP-1103 in Primary Cortical Neurons Exposed to Oxygen and Glucose Deprivation.
    International journal of molecular sciences, 2017, Jan-18, Volume: 18, Issue:1

    Topics: Animals; Apoptosis; Caspase 3; Cell Nucleus; Cerebral Cortex; Cyclopropanes; Cytochromes c; Enzyme Activation; Flurbiprofen; Glucose; Glycogen Synthase Kinase 3 beta; Ibuprofen; Mice, Inbred C57BL; Necrosis; Neurons; Neuroprotective Agents; Oxygen; p38 Mitogen-Activated Protein Kinases; Transcription Factor RelA

2017