ibuprofen and benoxaprofen

ibuprofen has been researched along with benoxaprofen in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199014 (56.00)18.7374
1990's1 (4.00)18.2507
2000's2 (8.00)29.6817
2010's8 (32.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boettcher, I; Elger, W; Kirsch, G; Siegmund, F; Wachtel, H1
Strassburg, CP; Tukey, RH1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Kumar, M; Sinha, VR; Thareja, S1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Greaves, MW1
Forbes, CD; Madhok, R; Pinkerton, L; Small, M; Steven, MM; Sturrock, RD1
Bagby, GF; O'Brien, WM1
Hamburger, SA; Hastings, GH; Judy, WV; Toth, PD1
Acosta, D; Sorensen, EM1
Caldwell, J; Hutt, AJ1
Bonney, RJ; Galavage, M; Goldenberg, M; Humes, JL; Kuehl, FA; Sadowski, S; Subers, E1
Mikulaschek, WM2
Grahame, R; Highton, J1
Glynne, A; Tyson, VC1
Gum, OB1
Alarcon-Segovia, D1
Ayalogu, EO; Gibson, GG; Ioannides, C; Lewis, DF; Rekka, E1
Dong, JQ; Smith, PC1

Reviews

4 review(s) available for ibuprofen and benoxaprofen

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Rare adverse reactions to nonsteroidal antiinflammatory drugs (3).
    The Journal of rheumatology, 1985, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Chemical and Drug Induced Liver Injury; Colitis; Digestive System; Esophagus; Female; Humans; Ibuprofen; Indomethacin; Liver; Male; Middle Aged; Pancreatitis; Phenylbutazone; Propionates; Sialadenitis

1985
The metabolic chiral inversion of 2-arylpropionic acids--a novel route with pharmacological consequences.
    The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:11

    Topics: Animals; Carbazoles; Fenoprofen; Humans; Ibuprofen; Indans; Naproxen; Phenylpropionates; Propionates; Stereoisomerism

1983

Trials

6 trial(s) available for ibuprofen and benoxaprofen

ArticleYear
Non-steroidal anti-inflammatory drugs in haemophilic arthritis. A clinical and laboratory study.
    Haemostasis, 1985, Volume: 15, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis; Blood Platelets; Clinical Trials as Topic; Hemophilia A; Humans; Ibuprofen; Middle Aged; Propionates; Salicylates

1985
Long-term safety of benoxaprofen.
    The Journal of rheumatology. Supplement, 1980, Volume: 6

    Topics: Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Benzoxazoles; Blood Urea Nitrogen; Clinical Trials as Topic; Double-Blind Method; Female; Follow-Up Studies; Gastrointestinal Diseases; Gastrointestinal Hemorrhage; Humans; Ibuprofen; L-Lactate Dehydrogenase; Male; Middle Aged; Nail Diseases; Osteoarthritis; Peptic Ulcer; Photosensitivity Disorders; Propionates; Time Factors

1980
Benoxaprofen in the treatment of osteoarthritis--a comparison with ibuprofen.
    The Journal of rheumatology. Supplement, 1980, Volume: 6

    Topics: Adult; Aged; Anti-Inflammatory Agents; Benzoxazoles; Clinical Trials as Topic; Double-Blind Method; Female; Hematologic Tests; Hip; Humans; Ibuprofen; Male; Middle Aged; Movement; Osteoarthritis; Propionates; Time Factors

1980
A comparative study of benoxaprofen and ibuprofen in osteoarthritis in general practice.
    The Journal of rheumatology. Supplement, 1980, Volume: 6

    Topics: Adult; Age Factors; Aged; Alkaline Phosphatase; Anti-Inflammatory Agents; Benzoxazoles; Clinical Trials as Topic; Double-Blind Method; Family Practice; Female; Gastrointestinal Diseases; Humans; Ibuprofen; Male; Middle Aged; Osteoarthritis; Propionates; Skin Diseases; Time Factors

1980
Long-term efficacy and safety of benoxaprofen: comparison with aspirin and ibuprofen in patients with active rheumatoid arthritis.
    The Journal of rheumatology. Supplement, 1980, Volume: 6

    Topics: Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Benzoxazoles; Blood Sedimentation; Clinical Trials as Topic; Double-Blind Method; Female; Hematocrit; Hemoglobins; Humans; Ibuprofen; Male; Middle Aged; Patient Compliance; Propionates; Time Factors

1980
Long-term treatment of symptomatic osteoarthritis with benoxaprofen. Double-blind comparison with aspirin and ibuprofen.
    The Journal of rheumatology. Supplement, 1980, Volume: 6

    Topics: Adult; Aged; Anti-Inflammatory Agents; Aspirin; Benzoxazoles; Clinical Trials as Topic; Double-Blind Method; Female; Hip Joint; Humans; Ibuprofen; Knee Joint; Male; Middle Aged; Movement; Osteoarthritis; Patient Compliance; Propionates; Time Factors

1980

Other Studies

15 other study(ies) available for ibuprofen and benoxaprofen

ArticleYear
Nonsteroidal antiinflammatory agents. 14. Synthesis and pharmacological profile of 6-chloro-5-(cyclopentylmethyl)indan-1-carboxylic acid.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Edema; Indans; Indenes; Male; Rats; Rats, Inbred Strains

1984
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
    European journal of medicinal chemistry, 2012, Volume: 53

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Pharmacology and significance of nonsteroidal anti-inflammatory drugs in the treatment of skin diseases.
    Journal of the American Academy of Dermatology, 1987, Volume: 16, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Dermatitis; Eicosanoic Acids; Humans; Ibuprofen; Leukotriene B4; Lipoxygenase Inhibitors; Propionates; Prostaglandins; Skin; Skin Diseases

1987
Benoxaprofen attenuation of lethal canine endotoxic shock.
    Circulatory shock, 1985, Volume: 15, Issue:2

    Topics: Animals; Cyclooxygenase Inhibitors; Disease Models, Animal; Dogs; Hemodynamics; Ibuprofen; Lipoxygenase Inhibitors; Male; Propionates; Shock, Septic

1985
Relative toxicities of several nonsteroidal antiinflammatory compounds in primary cultures of rat hepatocytes.
    Journal of toxicology and environmental health, 1985, Volume: 16, Issue:3-4

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Ibuprofen; Indomethacin; L-Lactate Dehydrogenase; Liver; Propionates; Rats; Rats, Inbred Strains; Time Factors

1985
Pharmacological effects of non-steroidal antiinflammatory agents on prostaglandin and leukotriene synthesis in mouse peritoneal macrophages.
    Biochemical pharmacology, 1983, Aug-01, Volume: 32, Issue:15

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Ascitic Fluid; Aspirin; Female; Guinea Pigs; Ibuprofen; Indomethacin; Macrophages; Male; Mice; Propionates; Prostaglandins; Pyrazoles; SRS-A; Zymosan

1983
An update on long-term efficacy and safety with benoxaprofen.
    European journal of rheumatology and inflammation, 1982, Volume: 5, Issue:2

    Topics: Alkaline Phosphatase; Anemia; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Humans; Ibuprofen; Kidney Diseases; Osteoarthritis; Peptic Ulcer; Photosensitivity Disorders; Propionates; Time Factors

1982
Induction of hepatic microsomal CYP4A activity and of peroxisomal beta-oxidation by two non-steroidal anti-inflammatory drugs.
    Archives of toxicology, 1994, Volume: 68, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Enzyme Induction; Ibuprofen; Immunoblotting; Male; Microbodies; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Phenylbutyrates; Propionates; Rats; Rats, Wistar

1994
Glucuronidation and covalent protein binding of benoxaprofen and flunoxaprofen in sandwich-cultured rat and human hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:12

    Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoxazoles; Biotransformation; Cell Culture Techniques; Collagen; Dose-Response Relationship, Drug; Drug Combinations; Feasibility Studies; Glucuronates; Glucuronosyltransferase; Hepatocytes; Humans; Ibuprofen; Kinetics; Laminin; Male; Microsomes, Liver; Models, Biological; Propionates; Protein Binding; Proteoglycans; Rats; Rats, Sprague-Dawley

2009