ibuprofen and ascorbic acid

ibuprofen has been researched along with ascorbic acid in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19904 (10.00)18.7374
1990's4 (10.00)18.2507
2000's9 (22.50)29.6817
2010's20 (50.00)24.3611
2020's3 (7.50)2.80

Authors

AuthorsStudies
Haque, N; Molvi, KI; Sudarsanam, V; Vasu, KK; Yerande, SG1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bharate, SS; Vishwakarma, RA1
Hampannavar, GA; Karpoormath, R; Palkar, MB; Shaikh, MS1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ameen, BAH; Dissanayake, AA; Nair, MG1
Asif, M; Husain, A; Iqbal, MA; Iram, F; Khan, SA1
Ding, F; Gao, Y; Guo, Y; He, X; Li, S; Li, X; Liu, Z; Nie, Y; Wen, D; Zhang, Y; Zhong, M1
Klinger, W; Reinicke, C1
Hockertz, S; Rogalla, K; Schettler, T1
Bailey, RT; Bonavina, L; Brewer, AR; Demeester, TR; Eypasch, EP; Smyrk, TC1
Sinitsyn, SP1
Baxter, CS; Lawrence, AT1
Bille-Hansen, V; Olsen, UB1
Malik, NS; Meek, KM1
Ahmad, M; Li, WQ; Morin, I; Su, S; Zafarullah, M1
Chen, YZ; Ung, CY1
Joshi, A; Macfarlane, TV; Parara, E1
Grant, A; Holman, DR; Martin, MC; Wilkinson, TJ1
Ayoğlu, F; Babuccu, O; Hoşnuter, M; Kargi, E; Payasli, C1
Knight, P; Podczeck, F1
Knight, PE; Newton, JM; Podczeck, F1
Aaref, M; Abd-Rabboh, L; Abdelrahman, S; Aly, H; El-Dib, M; Elsayed, A; Hassan, H; Nawwar, F1
Bak, I; Czompa, A; Gesztelyi, R; Haines, DD; Juhasz, B; Kalantari, H; Lekli, I; Mahmoud, FF; Tosaki, A; Varga, B1
Allemandi, D; Burgalassi, S; Chetoni, P; Monti, D; Palma, S; Saino, V; Tampucci, S1
Davé, RN; Ghoroi, C; Gurumurthy, L; Jallo, LJ; Patel, U1
Carter, SE; Faulkner, A; Rakobowchuk, M1
Chen, D; Li, X; Lu, Y; Wang, G1
Guo, L; Hai, L; Jin, X; Li, X; Liu, Q; Qu, B; Wu, X; Wu, Y; Zhao, Y1
Bačić, GG; Mojović, MD; Pavićević, AA; Popović-Bijelić, AD; Šušnjar, SV1
Barrows, J; Capece, M; Davé, RN1
Al-Nawaiseh, AM; Bishop, PA; Pritchett, RC1
Fujii, HG; Ito, T; Sasaki, K; Sato, S1
Babakhani, A; Busaileh, AZ; Marik, PE; Middendorf, MM1
Cepeda-Lopez, AC; Cervantes-Gracia, K; Delgado González, EA; Herter-Aeberli, I; Llanas-Cornejo, D; Stoffel, NU; Zimmermann, MB1
Abatzoglou, N; Dalvi, H; Gosselin, R; Lavoie, FB; Robert, G1

Reviews

3 review(s) available for ibuprofen and ascorbic acid

ArticleYear
An appraisal on recent medicinal perspective of curcumin degradant: Dehydrozingerone (DZG).
    Bioorganic & medicinal chemistry, 2016, Feb-15, Volume: 24, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Antifungal Agents; Antimalarials; Antineoplastic Agents, Phytogenic; Antioxidants; Curcumin; Drug Design; Humans; Molecular Structure; Platelet Aggregation Inhibitors; Styrenes; Zingiber officinale

2016
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Insights into the chemistry and therapeutic potential of furanones: A versatile pharmacophore.
    European journal of medicinal chemistry, 2019, Jun-01, Volume: 171

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Antineoplastic Agents; Antiviral Agents; Humans; Molecular Structure

2019

Trials

2 trial(s) available for ibuprofen and ascorbic acid

ArticleYear
A double-blind randomised controlled clinical trial of the effect of preoperative ibuprofen, diclofenac, paracetamol with codeine and placebo tablets for relief of postoperative pain after removal of impacted third molars.
    The British journal of oral & maxillofacial surgery, 2004, Volume: 42, Issue:4

    Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Ascorbic Acid; Codeine; Diclofenac; Double-Blind Method; Epidemiologic Methods; Female; Humans; Ibuprofen; Male; Middle Aged; Molar, Third; Pain Measurement; Pain, Postoperative; Premedication; Tooth Extraction; Tooth, Impacted; Treatment Outcome

2004
Ascorbic acid combined with ibuprofen in hypoxic ischemic encephalopathy: a randomized controlled trial.
    Journal of perinatology : official journal of the California Perinatal Association, 2009, Volume: 29, Issue:6

    Topics: Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid; Asphyxia Neonatorum; Developmental Disabilities; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypoxia-Ischemia, Brain; Ibuprofen; Infant, Newborn; Male

2009

Other Studies

35 other study(ies) available for ibuprofen and ascorbic acid

ArticleYear
Syntheses of new tetrasubstituted thiophenes as novel anti-inflammatory agents.
    European journal of medicinal chemistry, 2007, Volume: 42, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Rats; Structure-Activity Relationship; Thiophenes

2007
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
    Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7

    Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics

2015
Lipid Peroxidation and Cyclooxygenase Enzyme Inhibitory Compounds from Prangos haussknechtii.
    Journal of natural products, 2017, 09-22, Volume: 80, Issue:9

    Topics: Anti-Inflammatory Agents; Antioxidants; Coumarins; Cyclooxygenase Inhibitors; Lipid Peroxidation; Molecular Structure; Plant Extracts; Tetrazoles; Tetrazolium Salts; Thiazoles

2017
New organoselenides (NSAIDs-Se derivatives) as potential anticancer agents: Synthesis, biological evaluation and in silico calculations.
    European journal of medicinal chemistry, 2021, Jun-05, Volume: 218

    Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Structure; Organoselenium Compounds; Structure-Activity Relationship; Tumor Cells, Cultured

2021
Influence of ibuprofen on drug-metabolizing enzymes in rat liver in vivo and in vitro.
    Biochemical pharmacology, 1975, Jan-01, Volume: 24, Issue:1

    Topics: Aminopyrine N-Demethylase; Animals; Ascorbic Acid; Drug Synergism; Hexobarbital; Ibuprofen; Kinetics; Liver; Male; Pharmaceutical Preparations; Phenobarbital; Propionates; Rats; Sleep; Time Factors

1975
Effect of acetylsalicylic acid, ascorbate and ibuprofen on the macrophage system.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:8

    Topics: Animals; Ascorbic Acid; Aspirin; Bone Marrow Cells; Enzyme-Linked Immunosorbent Assay; Free Radicals; Ibuprofen; Interleukin-6; Macrophages; Mice; Mice, Inbred C57BL; Tumor Necrosis Factor-alpha; Virus Replication

1992
Drug-induced esophageal injury. Histopathological study in a rabbit model.
    Digestive diseases and sciences, 1990, Volume: 35, Issue:10

    Topics: Animals; Ascorbic Acid; Aspirin; Delayed-Action Preparations; Doxycycline; Esophagus; Ferrous Compounds; Ibuprofen; Potassium Chloride; Rabbits

1990
[Correction of metabolic disorders of the myocardium in acute myocardial infarct as an important factor in preventing the development of circulatory insufficiency].
    Kardiologiia, 1985, Volume: 25, Issue:7

    Topics: Animals; Aprotinin; Ascorbic Acid; Drug Therapy, Combination; Glutamates; Glutamic Acid; Heart Failure; Ibuprofen; Myocardial Infarction; Myocardium; Nandrolone; Nandrolone Decanoate; Nifedipine; Potassium Magnesium Aspartate; Propranolol; Rabbits; Sodium Oxybate; Vitamin E

1985
Specific inhibition of phorbol diester-induced granulocyte-macrophage progenitor cell (GM-CFU) differentiation by lipoxygenase inhibitors.
    Cancer letters, 1987, Volume: 37, Issue:3

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Ascorbic Acid; Butylated Hydroxyanisole; Cell Differentiation; Colony-Forming Units Assay; Dexamethasone; Granulocytes; Hematopoietic Stem Cells; Ibuprofen; Indomethacin; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Mice; Tetradecanoylphorbol Acetate

1987
Exaggerated hypotension by N-formylmethionylleucyl-phenylalanine in indomethacin pretreated rats. Role of toxic oxygen.
    Agents and actions, 1986, Volume: 17, Issue:5-6

    Topics: Animals; Ascorbic Acid; Blood Pressure; Dimethyl Sulfoxide; Endotoxins; Female; Glucagon; Hypotension; Ibuprofen; Indomethacin; Isoproterenol; N-Formylmethionine Leucyl-Phenylalanine; Oxygen; Rats; Rats, Inbred Strains; Theophylline

1986
Vitamins and analgesics in the prevention of collagen ageing.
    Age and ageing, 1996, Volume: 25, Issue:4

    Topics: Acetaminophen; Aged; Aging; Anti-Inflammatory Agents, Non-Steroidal; Ascorbic Acid; Aspirin; Cellular Senescence; Chelating Agents; Collagen; Cornea; Culture Techniques; Enzyme Inhibitors; Glycosylation; Guanidines; Humans; Ibuprofen; Pentetic Acid; Sclera; Vitamin E; Vitamins

1996
Induction of stromelysin gene expression by tumor necrosis factor alpha is inhibited by dexamethasone, salicylate, and N-acetylcysteine in synovial fibroblasts.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Cattle; Cells, Cultured; Dexamethasone; Fibroblasts; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Ibuprofen; Indomethacin; Matrix Metalloproteinase 3; Proline; Sodium Salicylate; Synovial Membrane; Thiocarbamates; Tissue Inhibitor of Metalloproteinase-3; Transcription Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha; Vitamin E

1999
Prediction of potential toxicity and side effect protein targets of a small molecule by a ligand-protein inverse docking approach.
    Journal of molecular graphics & modelling, 2001, Volume: 20, Issue:3

    Topics: Ascorbic Acid; Aspirin; Computer Simulation; Drug-Related Side Effects and Adverse Reactions; Gentamicins; Ibuprofen; Indinavir; Ligands; Models, Molecular; Molecular Structure; Neomycin; Penicillin G; Pharmaceutical Preparations; Proteins; Software; Tamoxifen

2001
Identification of recently handled materials by analysis of latent human fingerprints using infrared spectromicroscopy.
    Applied spectroscopy, 2005, Volume: 59, Issue:9

    Topics: Ascorbic Acid; Dairy Products; Dermatoglyphics; Forensic Sciences; Humans; Ibuprofen; Spectrophotometry, Infrared; Sweat; Sweetening Agents

2005
[The effect of combined use of vitamin C, vitamin E, and ibuprofen on flap viability: an experimental study].
    Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat, 2005, Volume: 14, Issue:5-6

    Topics: Animals; Ascorbic Acid; Drug Therapy, Combination; Ibuprofen; Injections, Intraperitoneal; Rats; Rats, Wistar; Surgical Flaps; Vitamin E; Wound Healing

2005
The evaluation of formulations for the preparation of pellets with high drug loading by extrusion/spheronization.
    Pharmaceutical development and technology, 2006, Volume: 11, Issue:3

    Topics: Ascorbic Acid; Buffers; Cellulose; Chemistry, Pharmaceutical; Drug Implants; Evaluation Studies as Topic; Hydrogen-Ion Concentration; Ibuprofen; Lactose; Particle Size; Powders; Rheology; Solubility; Technology, Pharmaceutical; Water

2006
The rheological properties of modified microcrystalline cellulose containing high levels of model drugs.
    Journal of pharmaceutical sciences, 2009, Volume: 98, Issue:6

    Topics: Ascorbic Acid; Carboxymethylcellulose Sodium; Cellulose; Elasticity; Excipients; Ibuprofen; Lactose; Pressure; Rheology; Stress, Mechanical; Viscosity; Water

2009
Summative interaction between astaxanthin, Ginkgo biloba extract (EGb761) and vitamin C in suppression of respiratory inflammation: a comparison with ibuprofen.
    Phytotherapy research : PTR, 2011, Volume: 25, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Ascorbic Acid; Asthma; Drug Therapy, Combination; Ginkgo biloba; Guinea Pigs; Ibuprofen; Male; Plant Extracts; Xanthophylls

2011
Optimization of skin permeation and distribution of ibuprofen by using nanostructures (coagels) based on alkyl vitamin C derivatives.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2010, Volume: 76, Issue:3

    Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ascorbic Acid; Drug Delivery Systems; Ibuprofen; Male; Nanostructures; Permeability; Polyethylene Glycols; Rats; Rats, Hairless; Skin; Skin Absorption

2010
Improvement of flow and bulk density of pharmaceutical powders using surface modification.
    International journal of pharmaceutics, 2012, Feb-28, Volume: 423, Issue:2

    Topics: Acetaminophen; Ascorbic Acid; Chemistry, Pharmaceutical; Drug Compounding; Excipients; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Magnetics; Microscopy, Electron, Scanning; Particle Size; Powders; Rheology; Silicon Dioxide; Surface Properties; Technology, Pharmaceutical

2012
The role of prostaglandin and antioxidant availability in recovery from forearm ischemia-reperfusion injury in humans.
    Journal of hypertension, 2014, Volume: 32, Issue:2

    Topics: Adult; Antioxidants; Ascorbic Acid; Blood Flow Velocity; Brachial Artery; Endothelium, Vascular; Female; Forearm; Forearm Injuries; Hemodynamics; Humans; Ibuprofen; Male; Prostaglandin Antagonists; Prostaglandins; Reperfusion Injury; Thioctic Acid; Ultrasonography; Vasodilation; Vitamin E; Young Adult

2014
Binding of ascorbic acid and α-tocopherol to bovine serum albumin: a comparative study.
    Molecular bioSystems, 2014, Volume: 10, Issue:2

    Topics: Adsorption; alpha-Tocopherol; Ascorbic Acid; Binding Sites; Calorimetry; Entropy; Hydrogen Bonding; Ibuprofen; Protein Binding; Serum Albumin, Bovine; Spectroscopy, Fourier Transform Infrared; Thermodynamics; Tryptophan; Tyrosine; Warfarin

2014
Design, synthesis and biological evaluation of brain targeting l-ascorbic acid prodrugs of ibuprofen with "lock-in" function.
    European journal of medicinal chemistry, 2014, Jul-23, Volume: 82

    Topics: Animals; Ascorbic Acid; Brain; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Design; Glucose Transporter Type 1; Ibuprofen; Mice; Mice, Inbred Strains; Molecular Structure; Prodrugs; Sodium-Coupled Vitamin C Transporters; Structure-Activity Relationship; Tissue Distribution

2014
Binding of doxyl stearic spin labels to human serum albumin: an EPR study.
    The journal of physical chemistry. B, 2014, Sep-18, Volume: 118, Issue:37

    Topics: Ascorbic Acid; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Ethanol; Humans; Ibuprofen; Protein Binding; Serum Albumin; Spin Labels; Temperature; Warfarin

2014
Controlled release from drug microparticles via solventless dry-polymer coating.
    Journal of pharmaceutical sciences, 2015, Volume: 104, Issue:4

    Topics: Ascorbic Acid; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diffusion; Ibuprofen; Kinetics; Models, Chemical; Particle Size; Polyethylenes; Solubility; Surface Properties; Technology, Pharmaceutical; Waxes

2015
Enhancing Short-Term Recovery After High-Intensity Anaerobic Exercise.
    Journal of strength and conditioning research, 2016, Volume: 30, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Ascorbic Acid; Creatine Kinase; Cross-Over Studies; Cryotherapy; Exercise; Humans; Ibuprofen; Immersion; Male; Myalgia; Physical Exertion; Random Allocation; Recovery of Function; Vitamin E; Whey Proteins; Young Adult

2016
Synthesis and Reduction Kinetics of Five Ibuprofen-Nitroxides for Ascorbic Acid and Methyl Radicals.
    Chemical & pharmaceutical bulletin, 2016, Volume: 64, Issue:10

    Topics: Ascorbic Acid; Free Radicals; Ibuprofen; Kinetics; Molecular Structure; Nitrogen Oxides; Oxidation-Reduction

2016
Stevens-Johnson syndrome/toxic epidermal necrolysis: treatment with low-dose corticosteroids, vitamin C and thiamine.
    BMJ case reports, 2019, Nov-02, Volume: 12, Issue:11

    Topics: Administration, Intravenous; Adrenal Cortex Hormones; Adult; Antioxidants; Ascorbic Acid; Drug Therapy, Combination; Female; Humans; Ibuprofen; Stevens-Johnson Syndrome; Thiamine; Vitamin B Complex

2019
The effects of reducing chronic inflammation in overweight women on serum hepcidin and iron absorption with and without supplemental ascorbic acid.
    The British journal of nutrition, 2021, 09-28, Volume: 126, Issue:6

    Topics: Adult; Ascorbic Acid; Female; Hepcidins; Humans; Ibuprofen; Inflammation; Interleukin-6; Intestinal Absorption; Iron; Middle Aged; Overweight; Young Adult

2021
Pharmaceutical tablet compression: measuring temporal and radial concentration profiles to better assess segregation.
    Pharmaceutical development and technology, 2022, Volume: 27, Issue:4

    Topics: Ascorbic Acid; Excipients; Ibuprofen; Powders; Tablets; Technology, Pharmaceutical

2022