ibuprofen has been researched along with arginine in 55 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 19 (34.55) | 18.2507 |
| 2000's | 18 (32.73) | 29.6817 |
| 2010's | 17 (30.91) | 24.3611 |
| 2020's | 1 (1.82) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Gray, DW; Marshall, I | 2 |
| Deshmukh, DR; Mukhopadhyay, A; Sarnaik, AP | 1 |
| Ceppi Monti, N; Gazzaniga, A; Gianesello, V; Lodola, E; Stroppolo, F | 1 |
| Miura, K; Okumura, M; Yamamoto, K; Yamashita, Y; Yukimura, T | 1 |
| Kishimoto, H; Morii, H; Tsumura, K; Uchimoto, S; Yamashita, N | 1 |
| Rivier, C | 1 |
| Iwao, H; Kim, S; Miura, K; Okada, T; Takai, M; Yamashita, Y; Yukimura, T | 1 |
| Björkman, R | 1 |
| Bryant, CE; Elliott, J; Soydan, J | 1 |
| Hellewell, PG; Teixeira, MM; Williams, TJ | 1 |
| Cai, B; Greenberg, S; Hyman, A; Kolls, J; Lippton, H; Nelson, S; Summer, WR; Wang, Y; Xie, J | 1 |
| Schmitt, JK | 1 |
| Bhattacharyya, DK; Garavito, M; Lecomte, M; Rieke, CJ; Smith, WL | 1 |
| Menzel, EJ; Reihsner, R | 1 |
| Bani, M; Brogin, G; Della Pepa, C; Eandi, M; Fornasini, G; Gallina, M; Monti, N; Persiani, S; Strolin Benedetti, M; Zara, G | 1 |
| Hadházy, P; Kocsis, E; Koltai, MZ; Pogátsa, G; Pósa, I; Rösen, P; Winkler, G | 1 |
| Barzoi, G; De Santis, D; Finco, G; Gilli, E; Gottin, L; Ischia, S; Polati, E; Salgarelli, A | 1 |
| Franchini, S; Granella, F; Lanfranchi, S; Manzoni, GC; Nappi, G; Sandrini, G | 1 |
| Alarcón, C; Bruseghini, L; Esteban, J; Esteras, A; Jiménez, D; Martin, MJ; Motilva, V; Pozo, D | 1 |
| Alvarez Calatayud, G; Figueras Nadal, C; García de Miguel, MJ; Gómez Campderá, A; Pou Fernández, J; Sánchez Bayle, M | 1 |
| Ardia, A; Mehlisch, DR; Pallotta, T | 1 |
| Ardia, A; Black, P; Desjardins, P; Max, MB; Norwood, T; Pallotta, T | 1 |
| Ardia, A; Black, P; Desjardins, P; Norris, L; Norwood, T; Papageorge, M; Shen, DD | 1 |
| Davies, C; DeVoss, JJ; Gillam, EM; Graham, SE; Pearson, A; Scott, JR; Witham, K | 1 |
| Baydoun, L; Daniels, R; Drust, A; Düvel, A; Goldhagen, T; Müller-Goymann, CC; Schwan, I; Zeidler, C | 1 |
| Alarcón de la Lastra, C; Bruseghini, L; Esteras, A; Herrerías, JM; Jiménez, MD; Martín, MJ; Motilva, V | 1 |
| Bruseghini, L; Esteras, A; Illanes, M; Martín-Lacave, I; Motilva, V; Sánchez-Fidalgo, S | 1 |
| Abad-Santos, F; Gallego-Sandín, S; Gálvez-Múgica, MA; Gisbert, JP; Khorrami, S; Novalbos, J; Pajares, JM; Rosado, A | 1 |
| Barbas, C; Huidobro, AL; Rupérez, FJ | 1 |
| Bernasconi, C; Bless, K; Ettlin, A; Ettlin, DA; Gallo, LM; Palla, S; Puhan, M; Tillmann, HC | 1 |
| Azanza, JR; Campanero, MA; Esteras, A; García-Quetglas, E; Gil-Aldea, I; Muñoz-Juarez, MJ; Sádaba, B | 1 |
| Gay, RE; Gay, S; Michel, BA; Sprott, H | 1 |
| Coombes, AG; Mohammed, AR; Perrie, Y | 1 |
| Cattaneo, D; Clementi, E; Cuzzocrea, S; De Palma, C; Di Paola, R; Mazzon, E; Perrotta, C; Trabucchi, E | 1 |
| Chow, RL; Lau, SL; Samman, N; Yeung, RW | 1 |
| Cattaneo, D; Clementi, E | 1 |
| Berrocoso, E; Leza, JC; Mico, JA; Ortega-Álvaro, A; Rey-Brea, R | 1 |
| Liu, J; Ma, H; Wang, H; Zhang, T; Zhu, M | 1 |
| Bhende, S; Jadhav, N | 1 |
| Han, J; Liu, HC; Wang, XL; Zhang, D | 1 |
| Chuang, VT; Ito, T; Kaneko, K; Maruyama, T; Otagiri, M; Suenaga, A; Watanabe, H | 1 |
| Bahr, MH; Hamza, M; Masoud, SI; Saad, SS | 1 |
| Abd-Alkhalek, HA; El-Bakly, WM; El-Lithy, GM; Hamza, M; Masoud, SI; Matboli, M | 1 |
| Ahmetaj-Shala, B; Etelvino, G; Gashaw, HH; Kirkby, NS; Leão, NM; Mitchell, JA; Sampaio, W; Santos, RA; Tesfai, A | 1 |
| Ahmetaj-Shala, B; Chan, MV; Constantinou, C; Galaris, G; Gashaw, H; Kirkby, NS; Leszczynski, R; Mazi, S; Mitchell, JA; Tesfai, A; Warner, TD | 1 |
| Allegretti, M; Antonosante, A; Aramini, A; Benedetti, E; Brandolini, L; Castelli, V; Catanesi, M; Cimini, A; Cristiano, L; d'Angelo, M; Giordano, A; Luini, A; Mayo, E; Parashuraman, S; Villa, S | 1 |
| Laitinen, R; Lerminiaux, L; Ojarinta, R | 1 |
| Korhonen, O; Laitinen, R; Ojarinta, R; Saarinen, J; Strachan, CJ | 1 |
| do Prado, AA; Ribeiro, MMAC; Richter, EM | 1 |
3 review(s) available for ibuprofen and arginine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Central antinociceptive effects of non-steroidal anti-inflammatory drugs and paracetamol. Experimental studies in the rat.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Behavior, Animal; Brain; Chemoreceptor Cells; Diclofenac; Ibuprofen; Male; Mechanoreceptors; Naloxone; Nociceptors; Pain; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Serotonin; Spinal Cord; Thermoreceptors | 1995 |
Clinical pharmacokinetics of ibuprofen arginine.
Topics: Absorption; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Arginine; Drug Combinations; Half-Life; Humans; Ibuprofen; Stereoisomerism | 2010 |
13 trial(s) available for ibuprofen and arginine
| Article | Year |
|---|---|
Activity and pharmacokinetics of a new oral dosage form of soluble ibuprofen.
Topics: Adult; Aged; Arginine; Biological Availability; Double-Blind Method; Female; Humans; Ibuprofen; Male; Middle Aged; Pain; Powders | 1992 |
Preliminary pharmacokinetic study of ibuprofen enantiomers after administration of a new oral formulation (ibuprofen arginine) to healthy male volunteers.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Arginine; Chromatography, High Pressure Liquid; Cross-Over Studies; Drug Combinations; Half-Life; Humans; Ibuprofen; Male; Spectrophotometry, Ultraviolet; Stereoisomerism | 1997 |
[Management of postoperative pain in stomatology with ibuprofen L-arginine and naproxen].
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Female; Humans; Ibuprofen; Informed Consent; Male; Middle Aged; Molar, Third; Naproxen; Pain, Postoperative; Tooth Extraction | 1998 |
Effectiveness of ibuprofen-arginine in the treatment of acute migraine attacks.
Topics: Acute Disease; Administration, Oral; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Arginine; Chi-Square Distribution; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Male; Migraine Disorders; Pain Measurement | 1998 |
Effectiveness and tolerability of ibuprofen-arginine versus paracetamol in children with fever of likely infectious origin.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Arginine; Child; Child, Preschool; Double-Blind Method; Drug Combinations; Endpoint Determination; Female; Fever; Humans; Ibuprofen; Male | 2002 |
A controlled comparative study of ibuprofen arginate versus conventional ibuprofen in the treatment of postoperative dental pain.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Arginine; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Ibuprofen; Male; Pain, Postoperative; Time Factors; Tooth Extraction | 2002 |
A randomized, double-blind, placebo-controlled comparison of the analgesic efficacy, onset of action, and tolerability of ibuprofen arginate and ibuprofen in postoperative dental pain.
Topics: Adult; Analgesics, Non-Narcotic; Arginine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Male; Pain Measurement; Pain, Postoperative; Tooth Extraction | 2002 |
Ibuprofen arginate provides effective relief from postoperative dental pain with a more rapid onset of action than ibuprofen.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Male; Oral Surgical Procedures; Pain, Postoperative; Time Factors; Tooth Extraction; Treatment Outcome | 2002 |
Comparison of gastric endoscopic lesions and tolerability to ibuprofen and ibuprofen-arginate in healthy subjects.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arginine; Drug Combinations; Gastric Mucosa; Gastroscopy; Humans; Ibuprofen; Peptic Ulcer; Prospective Studies; Reference Values; Severity of Illness Index | 2005 |
Ibuprofen arginine for pain control during scaling and root planing: a randomized, triple-blind trial.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Arginine; Chronic Disease; Dental Scaling; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Male; Middle Aged; Pain Measurement; Periodontitis; Root Planing; Statistics, Nonparametric; Toothache | 2006 |
A comparative study of the pharmacokinetics of ibuprofen arginate versus dexibuprofen in healthy volunteers.
Topics: Administration, Oral; Adolescent; Adult; Algorithms; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Arginine; Biological Availability; Chromatography, High Pressure Liquid; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Combinations; Epistaxis; Female; Half-Life; Headache; Humans; Ibuprofen; Male; Metabolic Clearance Rate; Stereoisomerism; Therapeutic Equivalency; Time Factors | 2006 |
Influence of ibuprofen-arginine on serum levels of nitric oxide metabolites in patients with chronic low back pain--a single-blind, placebo controlled pilot trial (ISRCTN18723747).
Topics: Analgesics; Arginine; Chronic Disease; Drug Combinations; Female; Humans; Ibuprofen; Low Back Pain; Male; Middle Aged; Nitric Oxide; Pain Measurement; Pilot Projects; Single-Blind Method; Treatment Outcome | 2006 |
Pre-emptive ibuprofen arginate in third molar surgery: a double-blind randomized controlled crossover clinical trial.
Topics: Adult; Analgesics, Non-Narcotic; Arginine; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Male; Molar, Third; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Postoperative Care; Premedication; Surveys and Questionnaires; Tooth Extraction; Young Adult | 2009 |
39 other study(ies) available for ibuprofen and arginine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Human alpha-calcitonin gene-related peptide stimulates adenylate cyclase and guanylate cyclase and relaxes rat thoracic aorta by releasing nitric oxide.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Aorta, Thoracic; Arginine; Calcitonin Gene-Related Peptide; Guanylate Cyclase; Hemoglobins; Ibuprofen; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Norepinephrine; Rats; Rats, Sprague-Dawley; Second Messenger Systems | 1992 |
Nitric oxide synthesis inhibitors attenuate calcitonin gene-related peptide endothelium-dependent vasorelaxation in rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Calcitonin Gene-Related Peptide; Endothelium, Vascular; Ibuprofen; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Inbred Strains | 1992 |
Interactions of ibuprofen with influenza infection and hyperammonemia in an animal model of Reye's syndrome.
Topics: Alanine Transaminase; Ammonia; Animals; Arginine; Aspartate Aminotransferases; Diet; Disease Models, Animal; Ferrets; Ibuprofen; Liver; Male; Orthomyxoviridae Infections; Reye Syndrome | 1992 |
Effects of endothelin-3 on renal functions.
Topics: Acetylcholine; Animals; Arginine; Dogs; Endothelins; Female; Ibuprofen; Kidney; Male; Nitroarginine; Nitroprusside; Renal Artery; Renal Circulation; Urodynamics; Vasodilator Agents | 1991 |
Implication of parathyroid hormone for the development of hypertension in young spontaneously hypertensive rats.
Topics: Acetylcholine; Analysis of Variance; Animals; Arginine; Blood Pressure; Drug Synergism; Hypertension; Ibuprofen; Infusion Pumps; Male; Nitroarginine; Parathyroid Hormone; Parathyroidectomy; Rats; Rats, Inbred SHR | 1995 |
Blockade of nitric oxide formation augments adrenocorticotropin released by blood-borne interleukin-1 beta: role of vasopressin, prostaglandins, and alpha 1-adrenergic receptors.
Topics: Adrenergic alpha-Antagonists; Adrenocorticotropic Hormone; Animals; Arginine; Drug Interactions; Ibuprofen; Interleukin-1; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Vasopressins | 1995 |
Renal vasodilating and diuretic actions of a selective endothelin ETB receptor agonist, IRL1620.
Topics: Animals; Arginine; Blood Pressure; Diuresis; Dogs; Endothelins; Female; Glomerular Filtration Rate; Heart Rate; Ibuprofen; Infusions, Intra-Arterial; Injections, Intravenous; Kidney; Male; Nitroarginine; Osmolar Concentration; Peptide Fragments; Receptors, Endothelin; Renal Circulation; Urination; Vasodilation | 1994 |
The role of nitric oxide in the responses of equine digital veins to vasodilator and vasoconstrictor agents.
Topics: Adenosine Triphosphate; Animals; Arginine; Bradykinin; Carbachol; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Hindlimb; Horses; Ibuprofen; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Phenylephrine; Vasoconstrictor Agents; Vasodilator Agents; Veins | 1994 |
Role of prostaglandins and nitric oxide in acute inflammatory reactions in guinea-pig skin.
Topics: Acute Disease; Alprostadil; Animals; Arginine; Dermatitis; Edema; Female; Guinea Pigs; Ibuprofen; Leukocytes; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Prostaglandins; Regional Blood Flow; Skin | 1993 |
Tumor necrosis factor-alpha inhibits endothelium-dependent relaxation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arginine; Cattle; Endothelium, Vascular; Histamine; Ibuprofen; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Pentoxifylline; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Pulmonary Veins; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents | 1993 |
Ibuprofen fails to increase plasma growth hormone levels in humans.
Topics: Adult; Analysis of Variance; Arginine; Blood Glucose; Female; Growth Hormone; Humans; Ibuprofen; Male; Reference Values; Time Factors | 1993 |
Involvement of arginine 120, glutamate 524, and tyrosine 355 in the binding of arachidonate and 2-phenylpropionic acid inhibitors to the cyclooxygenase active site of ovine prostaglandin endoperoxide H synthase-1.
Topics: Amino Acid Sequence; Animals; Arachidonic Acid; Arginine; Base Sequence; Binding Sites; Cyclooxygenase Inhibitors; DNA Primers; Enzyme Inhibitors; Flurbiprofen; Glutamates; Ibuprofen; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylpropionates; Prostaglandin-Endoperoxide Synthases; Protein Structure, Tertiary; Sheep; Structure-Activity Relationship; Tyrosine | 1996 |
Comparison of the effect of different inhibitors of the non-enzymatic glycation of rat tail tendons and bovine serum albumin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Dipeptides; Enzyme Inhibitors; Glycosylation; Guanidines; Ibuprofen; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Solubility; Tail; Tendons | 1996 |
Characteristics of coronary endothelial dysfunction in experimental diabetes.
Topics: Acetylcholine; Animals; Arginine; Coronary Circulation; Coronary Vessels; Cyclic GMP; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Nitric Oxide; Nitroprusside; Vasodilation; Vasodilator Agents | 1997 |
Mechanisms involved in protection afforded by L-arginine in ibuprofen-induced gastric damage: role of nitric oxide and prostaglandins.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Cyclic GMP; Gastric Mucosa; Ibuprofen; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Prostaglandins; Rats; Rats, Wistar | 2002 |
Assessment of arginine 97 and lysine 72 as determinants of substrate specificity in cytochrome P450 2C9 (CYP2C9).
Topics: Animals; Arginine; Aryl Hydrocarbon Hydroxylases; Base Sequence; Binding Sites; Cytochrome P-450 CYP2C9; Diclofenac; Escherichia coli; Gene Expression; Hemeproteins; Holoenzymes; Humans; Ibuprofen; Lysine; Models, Molecular; Mutagenesis, Site-Directed; NADPH-Ferrihemoprotein Reductase; Naproxen; Peptide Fragments; Recombinant Proteins; Sequence Homology, Nucleic Acid; Substrate Specificity | 2004 |
Comparison of different ibuprofen-amino acid compounds with respect to emulsifying and cytotoxic properties.
Topics: Adult; Animals; Arginine; Cornea; Drug Combinations; Drug Stability; Emulsifying Agents; Emulsions; Erythrocytes; Hemolysis; Humans; Ibuprofen; Lysine; Male; Surface Tension; Swine | 2004 |
Role of L-arginine in ibuprofen-induced oxidative stress and neutrophil infiltration in gastric mucosa.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Gastric Mucosa; Glutathione; Glutathione Peroxidase; Ibuprofen; Lipid Peroxidation; Male; Neutrophil Activation; Neutrophils; Oxidative Stress; Peroxidase; Protective Agents; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Time Factors; Xanthine Oxidase | 2004 |
Administration of L-arginine reduces the delay of the healing process caused by ibuprofen. Implication of COX and growth factors expression.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Fibroblast Growth Factor 2; Growth Substances; Ibuprofen; Male; Membrane Proteins; Neovascularization, Pathologic; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Stomach Ulcer; Vascular Endothelial Growth Factor A; Wound Healing | 2005 |
Tandem column for the simultaneous determination of arginine, ibuprofen and related impurities by liquid chromatography.
Topics: Arginine; Chromatography, High Pressure Liquid; Drug Combinations; Ibuprofen | 2006 |
Amino acids as cryoprotectants for liposomal delivery systems.
Topics: Amino Acids; Arginine; Chemistry, Pharmaceutical; Cholesterol; Cryoprotective Agents; Drug Carriers; Drug Compounding; Freeze Drying; Histidine; Ibuprofen; Lipids; Liposomes; Lysine; Particle Size; Phosphatidylcholines; Solubility; Technology, Pharmaceutical; Temperature; Time Factors; Trehalose; Viscosity; Water | 2007 |
Ibuprofen-arginine generates nitric oxide and has enhanced anti-inflammatory effects.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Arginine; Arthritis; Drug Combinations; HeLa Cells; Humans; Ibuprofen; Male; Mice; Mice, Inbred DBA; Nitric Oxide; Nitric Oxide Synthase; Peroxidase | 2009 |
Comparison of the antinociceptive effects of ibuprofen arginate and ibuprofen in rat models of inflammatory and neuropathic pain.
Topics: Analgesics, Non-Narcotic; Animals; Arginine; Cold Temperature; Disease Models, Animal; Drug Combinations; Ibuprofen; Inflammation; Male; Neuralgia; Physical Stimulation; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy | 2012 |
[Simultaneous determination of ibuprofen and arginine in ibuprofen injection using ultra performance liquid chromatography].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arginine; Chromatography, High Pressure Liquid; Ibuprofen; Injections, Intravenous; Solubility | 2011 |
Moringa coagulant as a stabilizer for amorphous solids: Part I.
Topics: Arginine; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Coagulants; Crystallography, X-Ray; Drug Stability; Excipients; Felodipine; Hydrogen Bonding; Ibuprofen; Kinetics; Meloxicam; Microscopy; Models, Molecular; Molecular Structure; Moringa oleifera; Plant Proteins; Solubility; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical; Thiazines; Thiazoles; Transition Temperature; X-Ray Diffraction | 2012 |
Pharmacokinetics of ibuprofen enantiomers in rats after intravenous and oral administration of ibuprofen arginate.
Topics: Absorption; Administration, Intravenous; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Arginine; Biological Availability; Chromatography, High Pressure Liquid; Drug Combinations; Ibuprofen; Male; Rats; Rats, Sprague-Dawley; Stereoisomerism | 2012 |
Arginine 485 of human serum albumin interacts with the benzophenone moiety of ketoprofen in the binding pocket of subdomain III A and III B.
Topics: Affinity Labels; Amino Acid Sequence; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Autoradiography; Benzophenones; Binding Sites; Chromatography, High Pressure Liquid; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Humans; Ibuprofen; Ketoprofen; Ligands; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Mutation; Photochemistry; Pichia; Protein Conformation; Recombinant Proteins; Serum Albumin | 2012 |
Nitric oxide is involved in ibuprofen preemptive analgesic effect in the plantar incisional model of postsurgical pain in mice.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Arginine; Hindlimb; Hyperalgesia; Ibuprofen; Male; Mice; Nitric Oxide; Pain, Postoperative; Physical Stimulation; Receptors, Adrenergic, alpha-2; Spinal Cord; Touch; Yohimbine | 2016 |
Prophylactic L-arginine and ibuprofen delay the development of tactile allodynia and suppress spinal miR-155 in a rat model of diabetic neuropathy.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Down-Regulation; Drug Therapy, Combination; Female; Hyperalgesia; Ibuprofen; MicroRNAs; Muscles; Nitric Oxide; Peripheral Nervous System Diseases; Rats, Wistar; Skin; Spinal Cord; Streptozocin; Up-Regulation | 2016 |
Ibuprofen arginate retains eNOS substrate activity and reverses endothelial dysfunction: implications for the COX-2/ADMA axis.
Topics: Animals; Arginine; Cyclooxygenase 2; Drug Combinations; Endothelium; Enzyme Inhibitors; Humans; Ibuprofen; Kidney; Male; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; Substrate Specificity | 2016 |
Pharmacological assessment of ibuprofen arginate on platelet aggregation and colon cancer cell killing.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Arginine; Caco-2 Cells; Cell Line, Tumor; Cell Survival; Cells, Cultured; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Combinations; Humans; Ibuprofen; Platelet Aggregation; Platelet Aggregation Inhibitors; Treatment Outcome | 2017 |
Differential protein modulation by ketoprofen and ibuprofen underlines different cellular response by gastric epithelium.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arginine; Cell Survival; Cytoprotection; Drug Combinations; Epithelial Cells; Ethanol; Gastric Mucosa; Gene Expression Profiling; Gene Regulatory Networks; Humans; Ibuprofen; Ketoprofen; Lysine; MCF-7 Cells; Oligonucleotide Array Sequence Analysis; Real-Time Polymerase Chain Reaction; Time Factors; Transcriptome | 2018 |
Spray drying of poorly soluble drugs from aqueous arginine solution.
Topics: Arginine; Calorimetry, Differential Scanning; Chromatography, High Pressure Liquid; Desiccation; Drug Combinations; Drug Compounding; Ibuprofen; Indomethacin; Powder Diffraction; Solubility; Solutions; Solvents; Spectroscopy, Fourier Transform Infrared; Water; X-Ray Diffraction | 2017 |
Preparation and characterization of multi-component tablets containing co-amorphous salts: Combining multimodal non-linear optical imaging with established analytical methods.
Topics: Administration, Oral; Arginine; Chemistry, Pharmaceutical; Drug Combinations; Drug Stability; Excipients; Ibuprofen; Indomethacin; Mannitol; Optical Imaging; Povidone; Salts; Solubility; Spectroscopy, Fourier Transform Infrared; Tablets; Technology, Pharmaceutical; X-Ray Diffraction; Xylitol | 2018 |
Ultra-rapid capillary zone electrophoresis method for simultaneous determination of arginine and ibuprofen.
Topics: Arginine; Electric Conductivity; Electrophoresis, Capillary; Ibuprofen | 2021 |