ibuprofen and arginine

ibuprofen has been researched along with arginine in 55 studies

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's19 (34.55)18.2507
2000's18 (32.73)29.6817
2010's17 (30.91)24.3611
2020's1 (1.82)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gray, DW; Marshall, I2
Deshmukh, DR; Mukhopadhyay, A; Sarnaik, AP1
Ceppi Monti, N; Gazzaniga, A; Gianesello, V; Lodola, E; Stroppolo, F1
Miura, K; Okumura, M; Yamamoto, K; Yamashita, Y; Yukimura, T1
Kishimoto, H; Morii, H; Tsumura, K; Uchimoto, S; Yamashita, N1
Rivier, C1
Iwao, H; Kim, S; Miura, K; Okada, T; Takai, M; Yamashita, Y; Yukimura, T1
Björkman, R1
Bryant, CE; Elliott, J; Soydan, J1
Hellewell, PG; Teixeira, MM; Williams, TJ1
Cai, B; Greenberg, S; Hyman, A; Kolls, J; Lippton, H; Nelson, S; Summer, WR; Wang, Y; Xie, J1
Schmitt, JK1
Bhattacharyya, DK; Garavito, M; Lecomte, M; Rieke, CJ; Smith, WL1
Menzel, EJ; Reihsner, R1
Bani, M; Brogin, G; Della Pepa, C; Eandi, M; Fornasini, G; Gallina, M; Monti, N; Persiani, S; Strolin Benedetti, M; Zara, G1
Hadházy, P; Kocsis, E; Koltai, MZ; Pogátsa, G; Pósa, I; Rösen, P; Winkler, G1
Barzoi, G; De Santis, D; Finco, G; Gilli, E; Gottin, L; Ischia, S; Polati, E; Salgarelli, A1
Franchini, S; Granella, F; Lanfranchi, S; Manzoni, GC; Nappi, G; Sandrini, G1
Alarcón, C; Bruseghini, L; Esteban, J; Esteras, A; Jiménez, D; Martin, MJ; Motilva, V; Pozo, D1
Alvarez Calatayud, G; Figueras Nadal, C; García de Miguel, MJ; Gómez Campderá, A; Pou Fernández, J; Sánchez Bayle, M1
Ardia, A; Mehlisch, DR; Pallotta, T1
Ardia, A; Black, P; Desjardins, P; Max, MB; Norwood, T; Pallotta, T1
Ardia, A; Black, P; Desjardins, P; Norris, L; Norwood, T; Papageorge, M; Shen, DD1
Davies, C; DeVoss, JJ; Gillam, EM; Graham, SE; Pearson, A; Scott, JR; Witham, K1
Baydoun, L; Daniels, R; Drust, A; Düvel, A; Goldhagen, T; Müller-Goymann, CC; Schwan, I; Zeidler, C1
Alarcón de la Lastra, C; Bruseghini, L; Esteras, A; Herrerías, JM; Jiménez, MD; Martín, MJ; Motilva, V1
Bruseghini, L; Esteras, A; Illanes, M; Martín-Lacave, I; Motilva, V; Sánchez-Fidalgo, S1
Abad-Santos, F; Gallego-Sandín, S; Gálvez-Múgica, MA; Gisbert, JP; Khorrami, S; Novalbos, J; Pajares, JM; Rosado, A1
Barbas, C; Huidobro, AL; Rupérez, FJ1
Bernasconi, C; Bless, K; Ettlin, A; Ettlin, DA; Gallo, LM; Palla, S; Puhan, M; Tillmann, HC1
Azanza, JR; Campanero, MA; Esteras, A; García-Quetglas, E; Gil-Aldea, I; Muñoz-Juarez, MJ; Sádaba, B1
Gay, RE; Gay, S; Michel, BA; Sprott, H1
Coombes, AG; Mohammed, AR; Perrie, Y1
Cattaneo, D; Clementi, E; Cuzzocrea, S; De Palma, C; Di Paola, R; Mazzon, E; Perrotta, C; Trabucchi, E1
Chow, RL; Lau, SL; Samman, N; Yeung, RW1
Cattaneo, D; Clementi, E1
Berrocoso, E; Leza, JC; Mico, JA; Ortega-Álvaro, A; Rey-Brea, R1
Liu, J; Ma, H; Wang, H; Zhang, T; Zhu, M1
Bhende, S; Jadhav, N1
Han, J; Liu, HC; Wang, XL; Zhang, D1
Chuang, VT; Ito, T; Kaneko, K; Maruyama, T; Otagiri, M; Suenaga, A; Watanabe, H1
Bahr, MH; Hamza, M; Masoud, SI; Saad, SS1
Abd-Alkhalek, HA; El-Bakly, WM; El-Lithy, GM; Hamza, M; Masoud, SI; Matboli, M1
Ahmetaj-Shala, B; Etelvino, G; Gashaw, HH; Kirkby, NS; Leão, NM; Mitchell, JA; Sampaio, W; Santos, RA; Tesfai, A1
Ahmetaj-Shala, B; Chan, MV; Constantinou, C; Galaris, G; Gashaw, H; Kirkby, NS; Leszczynski, R; Mazi, S; Mitchell, JA; Tesfai, A; Warner, TD1
Allegretti, M; Antonosante, A; Aramini, A; Benedetti, E; Brandolini, L; Castelli, V; Catanesi, M; Cimini, A; Cristiano, L; d'Angelo, M; Giordano, A; Luini, A; Mayo, E; Parashuraman, S; Villa, S1
Laitinen, R; Lerminiaux, L; Ojarinta, R1
Korhonen, O; Laitinen, R; Ojarinta, R; Saarinen, J; Strachan, CJ1
do Prado, AA; Ribeiro, MMAC; Richter, EM1

Reviews

3 review(s) available for ibuprofen and arginine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Central antinociceptive effects of non-steroidal anti-inflammatory drugs and paracetamol. Experimental studies in the rat.
    Acta anaesthesiologica Scandinavica. Supplementum, 1995, Volume: 103

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Behavior, Animal; Brain; Chemoreceptor Cells; Diclofenac; Ibuprofen; Male; Mechanoreceptors; Naloxone; Nociceptors; Pain; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Receptors, Serotonin; Spinal Cord; Thermoreceptors

1995
Clinical pharmacokinetics of ibuprofen arginine.
    Current clinical pharmacology, 2010, Volume: 5, Issue:4

    Topics: Absorption; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Arginine; Drug Combinations; Half-Life; Humans; Ibuprofen; Stereoisomerism

2010

Trials

13 trial(s) available for ibuprofen and arginine

ArticleYear
Activity and pharmacokinetics of a new oral dosage form of soluble ibuprofen.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:4

    Topics: Adult; Aged; Arginine; Biological Availability; Double-Blind Method; Female; Humans; Ibuprofen; Male; Middle Aged; Pain; Powders

1992
Preliminary pharmacokinetic study of ibuprofen enantiomers after administration of a new oral formulation (ibuprofen arginine) to healthy male volunteers.
    Chirality, 1997, Volume: 9, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Arginine; Chromatography, High Pressure Liquid; Cross-Over Studies; Drug Combinations; Half-Life; Humans; Ibuprofen; Male; Spectrophotometry, Ultraviolet; Stereoisomerism

1997
[Management of postoperative pain in stomatology with ibuprofen L-arginine and naproxen].
    Minerva stomatologica, 1998, Volume: 47, Issue:6

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Female; Humans; Ibuprofen; Informed Consent; Male; Middle Aged; Molar, Third; Naproxen; Pain, Postoperative; Tooth Extraction

1998
Effectiveness of ibuprofen-arginine in the treatment of acute migraine attacks.
    International journal of clinical pharmacology research, 1998, Volume: 18, Issue:3

    Topics: Acute Disease; Administration, Oral; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Arginine; Chi-Square Distribution; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Male; Migraine Disorders; Pain Measurement

1998
Effectiveness and tolerability of ibuprofen-arginine versus paracetamol in children with fever of likely infectious origin.
    Acta paediatrica (Oslo, Norway : 1992), 2002, Volume: 91, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Arginine; Child; Child, Preschool; Double-Blind Method; Drug Combinations; Endpoint Determination; Female; Fever; Humans; Ibuprofen; Male

2002
A controlled comparative study of ibuprofen arginate versus conventional ibuprofen in the treatment of postoperative dental pain.
    Journal of clinical pharmacology, 2002, Volume: 42, Issue:8

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Arginine; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Ibuprofen; Male; Pain, Postoperative; Time Factors; Tooth Extraction

2002
A randomized, double-blind, placebo-controlled comparison of the analgesic efficacy, onset of action, and tolerability of ibuprofen arginate and ibuprofen in postoperative dental pain.
    Clinical therapeutics, 2002, Volume: 24, Issue:7

    Topics: Adult; Analgesics, Non-Narcotic; Arginine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Male; Pain Measurement; Pain, Postoperative; Tooth Extraction

2002
Ibuprofen arginate provides effective relief from postoperative dental pain with a more rapid onset of action than ibuprofen.
    European journal of clinical pharmacology, 2002, Volume: 58, Issue:6

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Male; Oral Surgical Procedures; Pain, Postoperative; Time Factors; Tooth Extraction; Treatment Outcome

2002
Comparison of gastric endoscopic lesions and tolerability to ibuprofen and ibuprofen-arginate in healthy subjects.
    Journal of clinical gastroenterology, 2005, Volume: 39, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arginine; Drug Combinations; Gastric Mucosa; Gastroscopy; Humans; Ibuprofen; Peptic Ulcer; Prospective Studies; Reference Values; Severity of Illness Index

2005
Ibuprofen arginine for pain control during scaling and root planing: a randomized, triple-blind trial.
    Journal of clinical periodontology, 2006, Volume: 33, Issue:5

    Topics: Adult; Aged; Analgesics, Non-Narcotic; Arginine; Chronic Disease; Dental Scaling; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Male; Middle Aged; Pain Measurement; Periodontitis; Root Planing; Statistics, Nonparametric; Toothache

2006
A comparative study of the pharmacokinetics of ibuprofen arginate versus dexibuprofen in healthy volunteers.
    European journal of clinical pharmacology, 2006, Volume: 62, Issue:10

    Topics: Administration, Oral; Adolescent; Adult; Algorithms; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Arginine; Biological Availability; Chromatography, High Pressure Liquid; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Combinations; Epistaxis; Female; Half-Life; Headache; Humans; Ibuprofen; Male; Metabolic Clearance Rate; Stereoisomerism; Therapeutic Equivalency; Time Factors

2006
Influence of ibuprofen-arginine on serum levels of nitric oxide metabolites in patients with chronic low back pain--a single-blind, placebo controlled pilot trial (ISRCTN18723747).
    The Journal of rheumatology, 2006, Volume: 33, Issue:12

    Topics: Analgesics; Arginine; Chronic Disease; Drug Combinations; Female; Humans; Ibuprofen; Low Back Pain; Male; Middle Aged; Nitric Oxide; Pain Measurement; Pilot Projects; Single-Blind Method; Treatment Outcome

2006
Pre-emptive ibuprofen arginate in third molar surgery: a double-blind randomized controlled crossover clinical trial.
    Australian dental journal, 2009, Volume: 54, Issue:4

    Topics: Adult; Analgesics, Non-Narcotic; Arginine; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Humans; Ibuprofen; Male; Molar, Third; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Postoperative Care; Premedication; Surveys and Questionnaires; Tooth Extraction; Young Adult

2009

Other Studies

39 other study(ies) available for ibuprofen and arginine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Human alpha-calcitonin gene-related peptide stimulates adenylate cyclase and guanylate cyclase and relaxes rat thoracic aorta by releasing nitric oxide.
    British journal of pharmacology, 1992, Volume: 107, Issue:3

    Topics: Acetylcholine; Adenylyl Cyclases; Animals; Aorta, Thoracic; Arginine; Calcitonin Gene-Related Peptide; Guanylate Cyclase; Hemoglobins; Ibuprofen; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Norepinephrine; Rats; Rats, Sprague-Dawley; Second Messenger Systems

1992
Nitric oxide synthesis inhibitors attenuate calcitonin gene-related peptide endothelium-dependent vasorelaxation in rat aorta.
    European journal of pharmacology, 1992, Feb-25, Volume: 212, Issue:1

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Calcitonin Gene-Related Peptide; Endothelium, Vascular; Ibuprofen; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Norepinephrine; omega-N-Methylarginine; Rats; Rats, Inbred Strains

1992
Interactions of ibuprofen with influenza infection and hyperammonemia in an animal model of Reye's syndrome.
    Pediatric research, 1992, Volume: 31, Issue:3

    Topics: Alanine Transaminase; Ammonia; Animals; Arginine; Aspartate Aminotransferases; Diet; Disease Models, Animal; Ferrets; Ibuprofen; Liver; Male; Orthomyxoviridae Infections; Reye Syndrome

1992
Effects of endothelin-3 on renal functions.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:3

    Topics: Acetylcholine; Animals; Arginine; Dogs; Endothelins; Female; Ibuprofen; Kidney; Male; Nitroarginine; Nitroprusside; Renal Artery; Renal Circulation; Urodynamics; Vasodilator Agents

1991
Implication of parathyroid hormone for the development of hypertension in young spontaneously hypertensive rats.
    Mineral and electrolyte metabolism, 1995, Volume: 21, Issue:1-3

    Topics: Acetylcholine; Analysis of Variance; Animals; Arginine; Blood Pressure; Drug Synergism; Hypertension; Ibuprofen; Infusion Pumps; Male; Nitroarginine; Parathyroid Hormone; Parathyroidectomy; Rats; Rats, Inbred SHR

1995
Blockade of nitric oxide formation augments adrenocorticotropin released by blood-borne interleukin-1 beta: role of vasopressin, prostaglandins, and alpha 1-adrenergic receptors.
    Endocrinology, 1995, Volume: 136, Issue:8

    Topics: Adrenergic alpha-Antagonists; Adrenocorticotropic Hormone; Animals; Arginine; Drug Interactions; Ibuprofen; Interleukin-1; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Vasopressins

1995
Renal vasodilating and diuretic actions of a selective endothelin ETB receptor agonist, IRL1620.
    European journal of pharmacology, 1994, Nov-03, Volume: 264, Issue:3

    Topics: Animals; Arginine; Blood Pressure; Diuresis; Dogs; Endothelins; Female; Glomerular Filtration Rate; Heart Rate; Ibuprofen; Infusions, Intra-Arterial; Injections, Intravenous; Kidney; Male; Nitroarginine; Osmolar Concentration; Peptide Fragments; Receptors, Endothelin; Renal Circulation; Urination; Vasodilation

1994
The role of nitric oxide in the responses of equine digital veins to vasodilator and vasoconstrictor agents.
    Equine veterinary journal, 1994, Volume: 26, Issue:5

    Topics: Adenosine Triphosphate; Animals; Arginine; Bradykinin; Carbachol; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Hindlimb; Horses; Ibuprofen; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Phenylephrine; Vasoconstrictor Agents; Vasodilator Agents; Veins

1994
Role of prostaglandins and nitric oxide in acute inflammatory reactions in guinea-pig skin.
    British journal of pharmacology, 1993, Volume: 110, Issue:4

    Topics: Acute Disease; Alprostadil; Animals; Arginine; Dermatitis; Edema; Female; Guinea Pigs; Ibuprofen; Leukocytes; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Prostaglandins; Regional Blood Flow; Skin

1993
Tumor necrosis factor-alpha inhibits endothelium-dependent relaxation.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 74, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arginine; Cattle; Endothelium, Vascular; Histamine; Ibuprofen; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; omega-N-Methylarginine; Pentoxifylline; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Pulmonary Veins; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents

1993
Ibuprofen fails to increase plasma growth hormone levels in humans.
    The American journal of the medical sciences, 1993, Volume: 305, Issue:5

    Topics: Adult; Analysis of Variance; Arginine; Blood Glucose; Female; Growth Hormone; Humans; Ibuprofen; Male; Reference Values; Time Factors

1993
Involvement of arginine 120, glutamate 524, and tyrosine 355 in the binding of arachidonate and 2-phenylpropionic acid inhibitors to the cyclooxygenase active site of ovine prostaglandin endoperoxide H synthase-1.
    The Journal of biological chemistry, 1996, Jan-26, Volume: 271, Issue:4

    Topics: Amino Acid Sequence; Animals; Arachidonic Acid; Arginine; Base Sequence; Binding Sites; Cyclooxygenase Inhibitors; DNA Primers; Enzyme Inhibitors; Flurbiprofen; Glutamates; Ibuprofen; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylpropionates; Prostaglandin-Endoperoxide Synthases; Protein Structure, Tertiary; Sheep; Structure-Activity Relationship; Tyrosine

1996
Comparison of the effect of different inhibitors of the non-enzymatic glycation of rat tail tendons and bovine serum albumin.
    Annals of clinical biochemistry, 1996, Volume: 33 ( Pt 3)

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Dipeptides; Enzyme Inhibitors; Glycosylation; Guanidines; Ibuprofen; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Solubility; Tail; Tendons

1996
Characteristics of coronary endothelial dysfunction in experimental diabetes.
    Cardiovascular research, 1997, Volume: 34, Issue:1

    Topics: Acetylcholine; Animals; Arginine; Coronary Circulation; Coronary Vessels; Cyclic GMP; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Nitric Oxide; Nitroprusside; Vasodilation; Vasodilator Agents

1997
Mechanisms involved in protection afforded by L-arginine in ibuprofen-induced gastric damage: role of nitric oxide and prostaglandins.
    Digestive diseases and sciences, 2002, Volume: 47, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Cyclic GMP; Gastric Mucosa; Ibuprofen; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Prostaglandins; Rats; Rats, Wistar

2002
Assessment of arginine 97 and lysine 72 as determinants of substrate specificity in cytochrome P450 2C9 (CYP2C9).
    Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:4

    Topics: Animals; Arginine; Aryl Hydrocarbon Hydroxylases; Base Sequence; Binding Sites; Cytochrome P-450 CYP2C9; Diclofenac; Escherichia coli; Gene Expression; Hemeproteins; Holoenzymes; Humans; Ibuprofen; Lysine; Models, Molecular; Mutagenesis, Site-Directed; NADPH-Ferrihemoprotein Reductase; Naproxen; Peptide Fragments; Recombinant Proteins; Sequence Homology, Nucleic Acid; Substrate Specificity

2004
Comparison of different ibuprofen-amino acid compounds with respect to emulsifying and cytotoxic properties.
    International journal of pharmaceutics, 2004, Apr-15, Volume: 274, Issue:1-2

    Topics: Adult; Animals; Arginine; Cornea; Drug Combinations; Drug Stability; Emulsifying Agents; Emulsions; Erythrocytes; Hemolysis; Humans; Ibuprofen; Lysine; Male; Surface Tension; Swine

2004
Role of L-arginine in ibuprofen-induced oxidative stress and neutrophil infiltration in gastric mucosa.
    Free radical research, 2004, Volume: 38, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Gastric Mucosa; Glutathione; Glutathione Peroxidase; Ibuprofen; Lipid Peroxidation; Male; Neutrophil Activation; Neutrophils; Oxidative Stress; Peroxidase; Protective Agents; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Time Factors; Xanthine Oxidase

2004
Administration of L-arginine reduces the delay of the healing process caused by ibuprofen. Implication of COX and growth factors expression.
    Histology and histopathology, 2005, Volume: 20, Issue:2

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Fibroblast Growth Factor 2; Growth Substances; Ibuprofen; Male; Membrane Proteins; Neovascularization, Pathologic; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Stomach Ulcer; Vascular Endothelial Growth Factor A; Wound Healing

2005
Tandem column for the simultaneous determination of arginine, ibuprofen and related impurities by liquid chromatography.
    Journal of chromatography. A, 2006, Jun-30, Volume: 1119, Issue:1-2

    Topics: Arginine; Chromatography, High Pressure Liquid; Drug Combinations; Ibuprofen

2006
Amino acids as cryoprotectants for liposomal delivery systems.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2007, Volume: 30, Issue:5

    Topics: Amino Acids; Arginine; Chemistry, Pharmaceutical; Cholesterol; Cryoprotective Agents; Drug Carriers; Drug Compounding; Freeze Drying; Histidine; Ibuprofen; Lipids; Liposomes; Lysine; Particle Size; Phosphatidylcholines; Solubility; Technology, Pharmaceutical; Temperature; Time Factors; Trehalose; Viscosity; Water

2007
Ibuprofen-arginine generates nitric oxide and has enhanced anti-inflammatory effects.
    Pharmacological research, 2009, Volume: 60, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Arginine; Arthritis; Drug Combinations; HeLa Cells; Humans; Ibuprofen; Male; Mice; Mice, Inbred DBA; Nitric Oxide; Nitric Oxide Synthase; Peroxidase

2009
Comparison of the antinociceptive effects of ibuprofen arginate and ibuprofen in rat models of inflammatory and neuropathic pain.
    Life sciences, 2012, Jan-02, Volume: 90, Issue:1-2

    Topics: Analgesics, Non-Narcotic; Animals; Arginine; Cold Temperature; Disease Models, Animal; Drug Combinations; Ibuprofen; Inflammation; Male; Neuralgia; Physical Stimulation; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy

2012
[Simultaneous determination of ibuprofen and arginine in ibuprofen injection using ultra performance liquid chromatography].
    Se pu = Chinese journal of chromatography, 2011, Volume: 29, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arginine; Chromatography, High Pressure Liquid; Ibuprofen; Injections, Intravenous; Solubility

2011
Moringa coagulant as a stabilizer for amorphous solids: Part I.
    AAPS PharmSciTech, 2012, Volume: 13, Issue:2

    Topics: Arginine; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Coagulants; Crystallography, X-Ray; Drug Stability; Excipients; Felodipine; Hydrogen Bonding; Ibuprofen; Kinetics; Meloxicam; Microscopy; Models, Molecular; Molecular Structure; Moringa oleifera; Plant Proteins; Solubility; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical; Thiazines; Thiazoles; Transition Temperature; X-Ray Diffraction

2012
Pharmacokinetics of ibuprofen enantiomers in rats after intravenous and oral administration of ibuprofen arginate.
    Yao xue xue bao = Acta pharmaceutica Sinica, 2012, Volume: 47, Issue:1

    Topics: Absorption; Administration, Intravenous; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Arginine; Biological Availability; Chromatography, High Pressure Liquid; Drug Combinations; Ibuprofen; Male; Rats; Rats, Sprague-Dawley; Stereoisomerism

2012
Arginine 485 of human serum albumin interacts with the benzophenone moiety of ketoprofen in the binding pocket of subdomain III A and III B.
    Die Pharmazie, 2012, Volume: 67, Issue:5

    Topics: Affinity Labels; Amino Acid Sequence; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Autoradiography; Benzophenones; Binding Sites; Chromatography, High Pressure Liquid; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Humans; Ibuprofen; Ketoprofen; Ligands; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Mutation; Photochemistry; Pichia; Protein Conformation; Recombinant Proteins; Serum Albumin

2012
Nitric oxide is involved in ibuprofen preemptive analgesic effect in the plantar incisional model of postsurgical pain in mice.
    Neuroscience letters, 2016, Feb-12, Volume: 614

    Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Arginine; Hindlimb; Hyperalgesia; Ibuprofen; Male; Mice; Nitric Oxide; Pain, Postoperative; Physical Stimulation; Receptors, Adrenergic, alpha-2; Spinal Cord; Touch; Yohimbine

2016
Prophylactic L-arginine and ibuprofen delay the development of tactile allodynia and suppress spinal miR-155 in a rat model of diabetic neuropathy.
    Translational research : the journal of laboratory and clinical medicine, 2016, Volume: 177

    Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Down-Regulation; Drug Therapy, Combination; Female; Hyperalgesia; Ibuprofen; MicroRNAs; Muscles; Nitric Oxide; Peripheral Nervous System Diseases; Rats, Wistar; Skin; Spinal Cord; Streptozocin; Up-Regulation

2016
Ibuprofen arginate retains eNOS substrate activity and reverses endothelial dysfunction: implications for the COX-2/ADMA axis.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2016, Volume: 30, Issue:12

    Topics: Animals; Arginine; Cyclooxygenase 2; Drug Combinations; Endothelium; Enzyme Inhibitors; Humans; Ibuprofen; Kidney; Male; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; Substrate Specificity

2016
Pharmacological assessment of ibuprofen arginate on platelet aggregation and colon cancer cell killing.
    Biochemical and biophysical research communications, 2017, 03-18, Volume: 484, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Arginine; Caco-2 Cells; Cell Line, Tumor; Cell Survival; Cells, Cultured; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Combinations; Humans; Ibuprofen; Platelet Aggregation; Platelet Aggregation Inhibitors; Treatment Outcome

2017
Differential protein modulation by ketoprofen and ibuprofen underlines different cellular response by gastric epithelium.
    Journal of cellular physiology, 2018, Volume: 233, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arginine; Cell Survival; Cytoprotection; Drug Combinations; Epithelial Cells; Ethanol; Gastric Mucosa; Gene Expression Profiling; Gene Regulatory Networks; Humans; Ibuprofen; Ketoprofen; Lysine; MCF-7 Cells; Oligonucleotide Array Sequence Analysis; Real-Time Polymerase Chain Reaction; Time Factors; Transcriptome

2018
Spray drying of poorly soluble drugs from aqueous arginine solution.
    International journal of pharmaceutics, 2017, Oct-30, Volume: 532, Issue:1

    Topics: Arginine; Calorimetry, Differential Scanning; Chromatography, High Pressure Liquid; Desiccation; Drug Combinations; Drug Compounding; Ibuprofen; Indomethacin; Powder Diffraction; Solubility; Solutions; Solvents; Spectroscopy, Fourier Transform Infrared; Water; X-Ray Diffraction

2017
Preparation and characterization of multi-component tablets containing co-amorphous salts: Combining multimodal non-linear optical imaging with established analytical methods.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2018, Volume: 132

    Topics: Administration, Oral; Arginine; Chemistry, Pharmaceutical; Drug Combinations; Drug Stability; Excipients; Ibuprofen; Indomethacin; Mannitol; Optical Imaging; Povidone; Salts; Solubility; Spectroscopy, Fourier Transform Infrared; Tablets; Technology, Pharmaceutical; X-Ray Diffraction; Xylitol

2018
Ultra-rapid capillary zone electrophoresis method for simultaneous determination of arginine and ibuprofen.
    Journal of separation science, 2021, Volume: 44, Issue:13

    Topics: Arginine; Electric Conductivity; Electrophoresis, Capillary; Ibuprofen

2021