ibuprofen has been researched along with amyloid beta-peptides in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (42.11) | 29.6817 |
| 2010's | 10 (52.63) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Bulter, T; Das, P; Eriksen, JL; Findlay, KA; Golde, TE; Kang, DE; Koo, EH; Marquez-Sterling, N; Murphy, MP; Pietrzik, CU; Sagi, SA; Smith, TE; Wang, R; Weggen, S | 1 |
| Apochal, A; Blasko, I; Boeck, G; Grubeck-Loebenstein, B; Hartmann, T; Ransmayr, G | 1 |
| Beech, W; Chu, T; Cole, GM; Morihara, T; Ubeda, O | 1 |
| Babu-Khan, S; Biere, AL; Citron, M; Landreth, G; Liu, H; Vassar, R; Yan, Q; Zhang, J | 1 |
| Adani, R; Amitai, G; Avila, J; Farías, GG; Godoy, JA; Inestrosa, NC; Meshulam, H; Vázquez, MC | 1 |
| LeVine, H | 1 |
| Cui, MZ; Mao, G; Tan, J; Xu, X; Zhao, G | 1 |
| Cenacchi, V; Facchinetti, F; Hutter-Paier, B; Imbimbo, BP; Lanzillotta, A; Pizzi, M; Villetti, G; Volta, R; Windisch, M | 1 |
| Cataldi, A; Cerasa, LS; Di Stefano, A; Nasuti, C; Patruno, A; Pesce, M; Rapino, M; Sozio, P; Zara, S | 1 |
| Cacciatore, I; Cataldi, A; Cornacchia, C; D'Aurizio, E; Di Stefano, A; Iannitelli, A; Mollica, A; Nasuti, C; Pinnen, F; Sozio, P; Zara, S | 1 |
| Cataldi, A; Di Stefano, A; Nasuti, C; Rapino, M; Sozio, P; Zara, S | 1 |
| Li, MS; Ngo, ST | 1 |
| Futai, E; Ishiura, S; Watahiki, H; Yagishita, S | 1 |
| Kim, S; Klimov, DK; Lockhart, C | 1 |
| Cataldi, A; De Colli, M; Di Stefano, A; Nasuti, C; Pacella, S; Rapino, M; Sozio, P; Zara, S | 1 |
| Borjini, N; Gillis, C; Maurice, T; Meunier, J; Villard, V | 1 |
| Galasko, DR; Golde, TE; Koo, EH; Ling, IF | 1 |
| Elmaleh, DR; Forte, AM; Griciuc, A; Hudry, E; Quinti, L; Ran, C; Shen, X; Tanzi, RE; Wan, Y; Ward, J; Zhang, C | 1 |
| Baghcheghi, Y; Hosseini, M; Salmani, H; Samadi-Noshahr, Z | 1 |
19 other study(ies) available for ibuprofen and amyloid beta-peptides
| Article | Year |
|---|---|
A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid Endopeptidases; Brain; CHO Cells; Cricetinae; Disease Models, Animal; Endopeptidases; Enzyme-Linked Immunosorbent Assay; Humans; Ibuprofen; Indomethacin; Mass Spectrometry; Mice; Mice, Transgenic; Peptide Fragments; Prostaglandin-Endoperoxide Synthases; Sulindac; Tumor Cells, Cultured | 2001 |
Ibuprofen decreases cytokine-induced amyloid beta production in neuronal cells.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspartic Acid Endopeptidases; Brain; Cell Survival; Cytokines; Down-Regulation; Endopeptidases; Humans; Ibuprofen; Intercellular Adhesion Molecule-1; Interferon-gamma; Neuroblastoma; Neurons; Peptide Fragments; Pyruvate Kinase; Tubulin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2001 |
Selective inhibition of Abeta42 production by NSAID R-enantiomers.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Line; Culture Media, Conditioned; Dose-Response Relationship, Drug; Flurbiprofen; Humans; Ibuprofen; Kidney; Mutation; NF-kappa B; Peptide Fragments; Peptides; Stereoisomerism; Transfection | 2002 |
Anti-inflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Humans; Ibuprofen; Mice; Mice, Transgenic; Microglia; Peptide Fragments; Pioglitazone; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors | 2003 |
The anti-inflammatory and cholinesterase inhibitor bifunctional compound IBU-PO protects from beta-amyloid neurotoxicity by acting on Wnt signaling components.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents, Non-Steroidal; beta Catenin; Brain; Cells, Cultured; Cholinesterase Inhibitors; Cytoskeletal Proteins; Disease Models, Animal; Down-Regulation; Drug Compounding; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Ibuprofen; Intercellular Signaling Peptides and Proteins; Mice; Mice, Transgenic; Neuroprotective Agents; Peptide Fragments; Pyridinium Compounds; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Signal Transduction; Trans-Activators; Wnt Proteins | 2005 |
Multiple ligand binding sites on A beta(1-40) fibrils.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Binding Sites; Congo Red; Fluorescent Dyes; Humans; Ibuprofen; Ligands; Models, Chemical; Molecular Structure; Naproxen; Peptide Fragments; Protein Binding; Thiazoles | 2005 |
The same gamma-secretase accounts for the multiple intramembrane cleavages of APP.
Topics: Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbamates; Cell Line, Tumor; Cell Membrane; Dipeptides; Humans; Ibuprofen; Mice; Peptide Fragments; Sulindac | 2007 |
CHF5074, a novel gamma-secretase modulator, attenuates brain beta-amyloid pathology and learning deficit in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Brain; Cyclopropanes; Flurbiprofen; Humans; Ibuprofen; Learning Disabilities; Memory; Mice; Mice, Transgenic; Microglia; Mutation; Peptide Fragments; Plaque, Amyloid | 2009 |
NOS-mediated morphological and molecular modifications in rats infused with Aβ (1-40), as a model of Alzheimer's disease, in response to a new lipophilic molecular combination codrug-1.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Behavior, Animal; Cerebral Cortex; Disease Models, Animal; Drug Combinations; Humans; Ibuprofen; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peptide Fragments; Rats; Rats, Wistar | 2011 |
Ibuprofen and glutathione conjugate as a potential therapeutic agent for treating Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Stability; Glutathione; Ibuprofen; Male; Oxidative Stress; Peptide Fragments; Rats; Rats, Wistar; Reactive Oxygen Species; Time Factors | 2011 |
Ibuprofen and lipoic acid codrug 1 control Alzheimer's disease progression by down-regulating protein kinase C ε-mediated metalloproteinase 2 and 9 levels in β-amyloid infused Alzheimer's disease rat model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cerebral Cortex; Cyclooxygenase Inhibitors; Disease Progression; Down-Regulation; Drug Combinations; Ibuprofen; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Peptide Fragments; Protein Kinase C-epsilon; Rats; Rats, Wistar; Thioctic Acid | 2011 |
Curcumin binds to Aβ1-40 peptides and fibrils stronger than ibuprofen and naproxen.
Topics: Amyloid; Amyloid beta-Peptides; Binding Sites; Curcumin; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Models, Molecular; Naproxen; Peptide Fragments | 2012 |
CTF1-51, a truncated carboxyl-terminal fragment of amyloid precursor protein, suppresses the effects of Aβ42-lowering γ-secretase modulators.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; CHO Cells; Cricetinae; Cricetulus; Ibuprofen; Peptide Fragments; Sulindac | 2012 |
Explicit solvent molecular dynamics simulations of Aβ peptide interacting with ibuprofen ligands.
Topics: Amyloid beta-Peptides; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Ligands; Molecular Dynamics Simulation; Peptide Fragments; Protein Binding; Protein Structure, Secondary; Solvents | 2012 |
Ibuprofen and lipoic acid conjugate neuroprotective activity is mediated by Ngb/Akt intracellular signaling pathway in Alzheimer's disease rat model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Brain; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Disease Progression; Globins; Humans; Ibuprofen; Male; Memory; Nerve Tissue Proteins; Neuroglobin; Neuroprotective Agents; Peptide Fragments; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; Thioctic Acid | 2013 |
Brain toxicity and inflammation induced in vivo in mice by the amyloid-β forty-two inducer aftin-4, a roscovitine derivative.
Topics: Adenine; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Butyrates; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Encephalitis; Enzyme Inhibitors; Hippocampus; Hydrocarbons, Halogenated; Ibuprofen; Indans; Learning Disabilities; Male; Memory Disorders; Mice; Neuroprotective Agents; Oxidative Stress; Peptide Fragments; Piperidines | 2015 |
Modulation of Aβ42 in vivo by γ-secretase modulator in primates and humans.
Topics: Adult; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Agents, Non-Steroidal; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Female; Humans; Ibuprofen; Macaca fascicularis; Male; Peptide Fragments; Random Allocation; Time Factors; Treatment Outcome; Young Adult | 2015 |
Cromolyn Reduces Levels of the Alzheimer's Disease-Associated Amyloid β-Protein by Promoting Microglial Phagocytosis.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anti-Asthmatic Agents; Brain; Cromolyn Sodium; Disease Models, Animal; Drug Combinations; Drug Repositioning; Gene Expression; Humans; Ibuprofen; Male; Mice; Mice, Transgenic; Microglia; Neurons; Neuroprotective Agents; Peptide Fragments; Phagocytosis; Transgenes | 2018 |
The brain consequences of systemic inflammation were not fully alleviated by ibuprofen treatment in mice.
Topics: Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anxiety; Behavior, Animal; Brain; Cytokines; Depression; Encephalitis; Ibuprofen; Inflammation; Lipopolysaccharides; Male; Malondialdehyde; Memory Disorders; Mice; Mice, Inbred BALB C; Morris Water Maze Test; Peptide Fragments; Psychomotor Performance; Recognition, Psychology; Swimming | 2021 |