ibuprofen and amphotericin b

ibuprofen has been researched along with amphotericin b in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.33)18.7374
1990's3 (12.50)18.2507
2000's4 (16.67)29.6817
2010's12 (50.00)24.3611
2020's3 (12.50)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Bharate, SS; Vishwakarma, RA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Asif, M; Husain, A; Iqbal, MA; Iram, F; Khan, SA1
Capito, JE; El-Manawaty, MA; George, RF; Girgis, AS; Panda, SS; Salman, A; Samir, A; Thomas, SJ1
Bernard, GR; Hardie, WD; Swindell, BB; Wheeler, AP; Wright, PW1
Burnett, RJ; Reents, SB1
Gigliotti, F; Lott, L; Shenep, JL; Thornton, D1
Badr, K; Ebert, J; Frazer, M; Hardie, WD; Takahashi, K1
Bełtowski, J; Górny, D; Marciniak, A1
Chakrabarti, R; Kumar, S1
Alves, SH; Azevedo, MI; Botton, S; Cavalheiro, AS; Lovato, L; Santurio, JM; Spader, TB; Zanette, RA1
Alves, SH; Azevedo, MI; Rossato, L; Santurio, JM; Spader, TB; Tronco-Alves, GR; Venturini, TP; Weiler, CB1
Ogundeji, AO; Pohl, CH; Sebolai, OM1
Borba-Santos, LP; Ferreira-Pereira, A; Nucci, M; Rozental, S1
Kassie, GM; Kerr, M; Moffat, A; Pratt, N; Roughead, EE1

Reviews

2 review(s) available for ibuprofen and amphotericin b

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Insights into the chemistry and therapeutic potential of furanones: A versatile pharmacophore.
    European journal of medicinal chemistry, 2019, Jun-01, Volume: 171

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Antineoplastic Agents; Antiviral Agents; Humans; Molecular Structure

2019

Trials

1 trial(s) available for ibuprofen and amphotericin b

ArticleYear
Induction of prostaglandin synthesis as the mechanism responsible for the chills and fever produced by infusing amphotericin B.
    The Journal of infectious diseases, 1987, Volume: 156, Issue:5

    Topics: Adolescent; Adult; Amphotericin B; Animals; Child; Child, Preschool; Clinical Trials as Topic; Dinoprostone; Double-Blind Method; Female; Fever; Humans; Ibuprofen; Infusions, Parenteral; Leukocytes, Mononuclear; Macrophages; Male; Mice; Prostaglandins E; Shivering

1987

Other Studies

21 other study(ies) available for ibuprofen and amphotericin b

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
    Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7

    Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics

2015
Synthesis, pharmacological profile and 2D-QSAR studies of curcumin-amino acid conjugates as potential drug candidates.
    European journal of medicinal chemistry, 2020, Jun-15, Volume: 196

    Topics: Amino Acids; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Candida albicans; Carrageenan; Cell Proliferation; Curcumin; Dose-Response Relationship, Drug; Edema; Mice; Microbial Sensitivity Tests; Molecular Structure; Pain; Pseudomonas aeruginosa; Quantitative Structure-Activity Relationship; Rats; Salmonella typhi; Spleen; Staphylococcus aureus; Streptococcus pyogenes; Ulcer

2020
Effect of cyclooxygenase inhibition on amphotericin B-induced lung injury in awake sheep.
    The Journal of infectious diseases, 1992, Volume: 166, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Amphotericin B; Animals; Body Temperature; Ibuprofen; Infusions, Intravenous; Leukocyte Count; Lung; Lung Compliance; Pulmonary Ventilation; Pulmonary Wedge Pressure; Sheep; Thromboxane B2

1992
Premedication for amphotericin B-induced chills.
    Clinical pharmacy, 1989, Volume: 8, Issue:12

    Topics: Amphotericin B; Humans; Hypothermia; Ibuprofen; Premedication

1989
The effect of thromboxane A2 receptor antagonism on amphotericin B-induced renal vasoconstriction in the rat.
    Prostaglandins, 1993, Volume: 45, Issue:1

    Topics: Amphotericin B; Animals; Blood Flow Velocity; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Unsaturated; Glomerular Filtration Rate; Hydrazines; Ibuprofen; Male; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Renal Artery; Vasoconstriction

1993
Biphasic effect of protein kinase C on rat renal cortical Na+, K+-ATPase.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1998, Volume: 49, Issue:4

    Topics: Amiloride; Amphotericin B; Animals; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ibuprofen; Kidney Cortex; Male; Oxazines; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate

1998
Amphotericin B both inhibits and enhances T-cell proliferation: inhibitory effect is mediated through H(2)O(2) production via cyclooxygenase pathway by macrophages.
    Journal of cellular biochemistry, 2000, Volume: 77, Issue:3

    Topics: Amphotericin B; Animals; Anti-Bacterial Agents; Catalase; Cell Division; Cell Survival; Concanavalin A; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Hydrogen Peroxide; Ibuprofen; Ionomycin; Ionophores; Macrophages; Mercaptoethanol; Mice; Mice, Inbred BALB C; Prostaglandin-Endoperoxide Synthases; Receptors, Antigen, T-Cell; Signal Transduction; Spleen; T-Lymphocytes; Temperature; Tetradecanoylphorbol Acetate; Time Factors

2000
In vitro activity of terbinafine associated to amphotericin B, fluvastatin, rifampicin, metronidazole and ibuprofen against Pythium insidiosum.
    Veterinary microbiology, 2009, Jun-12, Volume: 137, Issue:3-4

    Topics: Amphotericin B; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Drug Synergism; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Fluvastatin; Ibuprofen; Indoles; Metronidazole; Microbial Sensitivity Tests; Naphthalenes; Pythium; Rifampin; Terbinafine

2009
In vitro synergisms obtained by amphotericin B and voriconazole associated with non-antifungal agents against Fusarium spp.
    Diagnostic microbiology and infectious disease, 2011, Volume: 71, Issue:2

    Topics: Amphotericin B; Antifungal Agents; Drug Synergism; Fungi; Fusarium; Ibuprofen; Itraconazole; Microbial Sensitivity Tests; Pyrimidines; Triazoles; Voriconazole

2011
Repurposing of Aspirin and Ibuprofen as Candidate Anti-Cryptococcus Drugs.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:8

    Topics: Amphotericin B; Animals; Antifungal Agents; Aspirin; Cell Death; Cell Line; Cryptococcosis; Cryptococcus; Drug Repositioning; Drug Resistance, Fungal; Fluconazole; Ibuprofen; Mice; RAW 264.7 Cells

2016
Anti-Sporothrix activity of ibuprofen combined with antifungal.
    Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2021, Volume: 52, Issue:1

    Topics: Amphotericin B; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Cell Membrane; Drug Synergism; Humans; Ibuprofen; Microbial Sensitivity Tests; Reactive Oxygen Species; Sporothrix; Sporotrichosis; Terbinafine

2021
Medicine-Induced Acute Kidney Injury Findings from Spontaneous Reporting Systems, Sequence Symmetry Analysis and a Case-Control Study with a Focus on Medicines Used in Primary Care.
    Drug safety, 2022, Volume: 45, Issue:11

    Topics: Acute Kidney Injury; Adverse Drug Reaction Reporting Systems; Amlodipine; Amphotericin B; Australia; Case-Control Studies; Ciprofloxacin; Diclofenac; Furosemide; Humans; Ibuprofen; Metformin; Naproxen; Omeprazole; Primary Health Care; Ramipril; Simvastatin; Spironolactone; Sulfamethoxazole; Telmisartan; Trimethoprim; Valacyclovir; Zoledronic Acid

2022