ibuprofen and alprostadil

ibuprofen has been researched along with alprostadil in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19909 (34.62)18.7374
1990's4 (15.38)18.2507
2000's7 (26.92)29.6817
2010's6 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Borst, P; de Haas, M; Kuil, A; Reid, G; van der Heijden, I; Wielinga, P; Wijnholds, J; Zelcer, N1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Bellman, K; Knegtel, RM; Settimo, L1
Campbell, AJ; Cloutier, CT; Davies, EA; Devine, MJ; Steinberg, SM1
Davis, RE; Fakouhi, D; Geis, S; Lanza, FL; Nissen, C; Rack, MF; Rubin, A1
Almawi, WY; Pope, BL1
Cordasco, DM; Rotrosen, J; Segarnick, DJ1
Goldman, CD; Rudloff, MA; Ternberg, JL1
Cikrit, D; Grosfeld, JL; Gross, K; Kamman, K; Katz, S; Ross, D; Weber, TR; Wolfe, M1
Jugdutt, BI1
Halushka, PV; Izui, S; Kelley, VE1
Hellewell, PG; Teixeira, MM; Williams, TJ1
Abran, D; Chemtob, S; Dumont, I; Hardy, P; Li, DY; Molotchnikoff, S; Peri, K; Varma, DR1
Bolle, P; Fidanza, S; Tucci, P1
Abel, S; Gelderblom, WC; Smuts, CM; Snyman, SD; Swanevelder, S1
Loutzenhiser, K; Loutzenhiser, R; Tang, L1
Kim, JM; Manchanda, R; Tsang, BK1
Barnard, MR; Frelinger, AL; Laposata, M; Linden, MD; Michelson, AD; Morris, JE; O'Sullivan, BP; Salem, RO; Spencer-Manzon, M1
Distefano, G1
Colquhoun, A; Gomes, RN1
Glennon, YC; Owen, SF; Panter, GH; Patel, A; Rand-Weaver, M; Sumpter, JP; Trollope, HT1

Reviews

1 review(s) available for ibuprofen and alprostadil

ArticleYear
[The pharmacological manipulation of Botallo's duct in the duct-dependent congenital cardiopathies and in the preterm infants with respiratory distress. A review and personal findings].
    Minerva pediatrica, 2005, Volume: 57, Issue:1

    Topics: Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Agents; Cerebral Angiography; Cyanosis; Cyclooxygenase Inhibitors; Ductus Arteriosus; Ductus Arteriosus, Patent; Heart Defects, Congenital; Heart Failure; Hemodynamics; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Respiratory Distress Syndrome, Newborn; Vasodilator Agents

2005

Trials

1 trial(s) available for ibuprofen and alprostadil

ArticleYear
A double-blind placebo-controlled comparison of the efficacy and safety of 50, 100, and 200 micrograms of misoprostol QID in the prevention of ibuprofen-induced gastric and duodenal mucosal lesions and symptoms.
    The American journal of gastroenterology, 1989, Volume: 84, Issue:6

    Topics: Adult; Alprostadil; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation; Duodenitis; Female; Gastritis; Humans; Ibuprofen; Male; Middle Aged; Misoprostol; Random Allocation

1989

Other Studies

24 other study(ies) available for ibuprofen and alprostadil

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Aug-05, Volume: 100, Issue:16

    Topics: Adenosine Triphosphate; Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cell Line; Cell Membrane; Diffusion; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Humans; Insecta; Multidrug Resistance-Associated Proteins; Prostaglandins; Prostaglandins A; Prostaglandins F; Ribosomal Proteins; RNA Interference; RNA, Small Interfering; Thromboxane B2; Time Factors

2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Ibuprofen plus prostaglandin E1 in a septic porcine model of adult respiratory distress syndrome.
    The Journal of trauma, 1989, Volume: 29, Issue:3

    Topics: Alprostadil; Animals; Disease Models, Animal; Drug Therapy, Combination; Hemodynamics; Ibuprofen; Pseudomonas aeruginosa; Pseudomonas Infections; Random Allocation; Respiratory Distress Syndrome; Stroke Volume; Swine; Vascular Resistance

1989
Induction of suppression by a murine nonspecific suppressor-inducer cell line (M1-A5). II. The role of prostaglandins.
    Journal of immunology (Baltimore, Md. : 1950), 1986, Mar-15, Volume: 136, Issue:6

    Topics: Alprostadil; Animals; Aspirin; Cell Line; Dinoprostone; Epoprostenol; Ibuprofen; Immune Tolerance; Kinetics; Lymphokines; Male; Mice; Prostaglandins; Prostaglandins E; Suppressor Factors, Immunologic; T-Lymphocytes, Regulatory

1986
Prostanoid modulation (mediation?) of certain behavioral effects of ethanol.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 23, Issue:1

    Topics: Alcoholism; Alprostadil; Animals; Aspirin; Brain; Ethanol; Fatty Acids; Fatty Acids, Essential; Fatty Acids, Unsaturated; gamma-Linolenic Acid; Humans; Ibuprofen; Indomethacin; Linoleic Acids; Linolenic Acids; Male; Mice; Oenothera biennis; Plant Oils; Prostaglandins; Prostaglandins E; Prostanoic Acids; Substance Withdrawal Syndrome

1985
Cytoprotective agents in experimental small bowel volvulus.
    Journal of pediatric surgery, 1987, Volume: 22, Issue:3

    Topics: Alprostadil; Animals; Aspirin; Ephedrine; Ibuprofen; Indomethacin; Intestinal Obstruction; Intestine, Small; Rats; Rats, Inbred Strains; Superoxide Dismutase

1987
Comparative effects of indomethacin, prostaglandin E1, and ibuprofen on bowel ischemia.
    Journal of pediatric surgery, 1983, Volume: 18, Issue:6

    Topics: Alprostadil; Animals; Ductus Arteriosus, Patent; Enterocolitis, Pseudomembranous; Ibuprofen; Indomethacin; Intestine, Small; Ischemia; Prostaglandins E; Rats; Rats, Inbred Strains; Risk

1983
Effect of PGE1, PGE2 and PGI2 on ventricular arrhythmias during myocardial infarction in conscious dogs: relation to infarct size.
    Prostaglandins and medicine, 1981, Volume: 7, Issue:5

    Topics: Alprostadil; Animals; Arrhythmias, Cardiac; Collateral Circulation; Dinoprostone; Dogs; Electrocardiography; Epoprostenol; Female; Heart Ventricles; Ibuprofen; Male; Myocardial Infarction; Nitroglycerin; Prostaglandins; Prostaglandins E

1981
Effect of ibuprofen, a fatty acid cyclooxygenase inhibitor, on murine lupus.
    Clinical immunology and immunopathology, 1982, Volume: 25, Issue:2

    Topics: Alprostadil; Animals; Antibodies, Antinuclear; Antigen-Antibody Complex; Cyclooxygenase Inhibitors; DNA; Female; Ibuprofen; Kidney Glomerulus; Lupus Erythematosus, Systemic; Mice; Mice, Inbred NZB; Prostaglandin Antagonists; Prostaglandins E; Proteinuria; Thromboxane B2

1982
Role of prostaglandins and nitric oxide in acute inflammatory reactions in guinea-pig skin.
    British journal of pharmacology, 1993, Volume: 110, Issue:4

    Topics: Acute Disease; Alprostadil; Animals; Arginine; Dermatitis; Edema; Female; Guinea Pigs; Ibuprofen; Leukocytes; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Prostaglandins; Regional Blood Flow; Skin

1993
Characterization and regulation of prostaglandin E2 receptor and receptor-coupled functions in the choroidal vasculature of the pig during development.
    Circulation research, 1997, Volume: 80, Issue:4

    Topics: Age Factors; Alprostadil; Animals; Animals, Newborn; Biphenyl Compounds; Choroid; Cyclic AMP; Cyclic GMP; Dinoprostone; Enzyme Inhibitors; Ibuprofen; Inositol 1,4,5-Trisphosphate; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Prostaglandins; Receptors, Prostaglandin E; Swine; Vasoconstriction; Vasodilation

1997
Response to isoprenaline of rabbit detrusor muscle following exposure to 5, 8, 11, 14 eicosatetraynoic acid. Role of prostanoids on beta-adrenergic-evoked response.
    Journal of autonomic pharmacology, 1999, Volume: 19, Issue:3

    Topics: Alprostadil; Animals; Arachidonic Acids; Cyclooxygenase Inhibitors; Dinoprostone; Drug Interactions; Evoked Potentials; Ibuprofen; In Vitro Techniques; Indomethacin; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Prostaglandins; Rabbits; Receptors, Adrenergic, beta; Time Factors

1999
Regulation of fatty acid biosynthesis as a possible mechanism for the mitoinhibitory effect of fumonisin B1 in primary rat hepatocytes.
    Prostaglandins, leukotrienes, and essential fatty acids, 1999, Volume: 61, Issue:4

    Topics: Alprostadil; Animals; Arachidonic Acid; Carboxylic Acids; Carcinogens, Environmental; Cell Death; Cell Division; Cells, Cultured; Dinoprostone; Epidermal Growth Factor; Fatty Acids; Fumonisins; Ibuprofen; Linoleic Acid; Liver; Mycotoxins; Rats

1999
Biphasic actions of prostaglandin E(2) on the renal afferent arteriole : role of EP(3) and EP(4) receptors.
    Circulation research, 2000, Mar-31, Volume: 86, Issue:6

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Alprostadil; Angiotensin II; Animals; Arterioles; Dinoprostone; Drug Synergism; Hydronephrosis; Ibuprofen; In Vitro Techniques; Male; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Receptors, Prostaglandin E, EP4 Subtype; Renal Circulation; RNA, Messenger; Vasoconstriction; Vasodilation

2000
Role of prostaglandins in the suppression of apoptosis in hen granulosa cells by transforming growth factor alpha.
    Reproduction (Cambridge, England), 2001, Volume: 122, Issue:1

    Topics: Alprostadil; Animals; Apoptosis; Arachidonic Acid; Arachidonic Acids; Aristolochic Acids; Cells, Cultured; Chickens; Chromatin; Culture Media, Serum-Free; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; DNA Fragmentation; Enzyme Inhibitors; Female; Granulosa Cells; Ibuprofen; Nitrobenzenes; Phenanthrenes; Phospholipases A; Prostaglandins; Prostaglandins E; Prostaglandins F; Sulfonamides; Transforming Growth Factor alpha

2001
Platelet activation in cystic fibrosis.
    Blood, 2005, Jun-15, Volume: 105, Issue:12

    Topics: Adenylyl Cyclases; Adolescent; Adult; Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Blood Platelets; Blotting, Western; Case-Control Studies; Cell Membrane; Child; Cyclic AMP; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Fatty Acids; Genotype; Humans; Ibuprofen; Inflammation; Leukocytes; Monocytes; Neutrophils; P-Selectin; Platelet Activation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thromboxane A2; Time Factors; Vitamin E

2005
E series prostaglandins alter the proliferative, apoptotic and migratory properties of T98G human glioma cells in vitro.
    Lipids in health and disease, 2012, Dec-11, Volume: 11

    Topics: Alprostadil; Apoptosis; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclooxygenase 2; Dinoprostone; Glioma; Humans; Ibuprofen

2012
Testing the "read-across hypothesis" by investigating the effects of ibuprofen on fish.
    Chemosphere, 2016, Volume: 163

    Topics: Alprostadil; Animals; Cyclooxygenase Inhibitors; Cyprinidae; Humans; Ibuprofen; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; Tandem Mass Spectrometry

2016