ibuprofen has been researched along with allopurinol in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (11.11) | 18.7374 |
| 1990's | 7 (19.44) | 18.2507 |
| 2000's | 14 (38.89) | 29.6817 |
| 2010's | 11 (30.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Kobayashi, Y; Kohyama, N; Ohbayashi, M; Ohshiro, N; Tsuchiya, A; Yamamoto, T | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Bhatia, G; Khanna, AK; Kumar, M; Modukuri, RK; Rai, S; Sashidhara, KV; Shukla, R; Sonkar, R | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Beuving, LJ; Fleckenstein, AE; Hall, ED; Linseman, KL; Smith, SL | 1 |
| Demling, RH; LaLonde, C | 2 |
| Lucchesi, BR; Mickelson, JK; Simpson, PJ | 1 |
| Coran, AG; Drongowski, RA; Schmeling, DJ | 1 |
| Shah, SV | 1 |
| Abran, D; Chemtob, S; Fernandez, H; Roy, MS; Varma, DR | 1 |
| Deitch, EA; Mainous, MR; Xu, D | 1 |
| Ayan, F; Cetinkale, O; Demir, M; Onsel, C; Sayman, HB | 1 |
| Belzer, FO; Saunder, A; Schilling, M; Southard, JH | 1 |
| Biagioli, MC; Kaul, P; Singh, I; Turner, RB | 1 |
| Alarcón de la Lastra, C; Bruseghini, L; Esteras, A; Herrerías, JM; Jiménez, MD; Martín, MJ; Motilva, V | 1 |
| Ara, I; Bhurgri, H; Choudhary, MI; Gowani, SA; Jalil, S; Khan, A; Saeed, SA; Waqar, MA; Waqar, SN; Zaidi, AH; Zubairi, AJ | 1 |
| Gold, J; Greeve, JM; Klima, U; Kofidis, T; Lebl, DR; Robbins, RC; Swijnenburg, RJ; Xu, C | 1 |
| Hoshide, S; Kanou, M; Mukoyoshi, M; Muroga, H; Nishimura, S; Taniguchi, K; Umeda, S | 1 |
3 review(s) available for ibuprofen and allopurinol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Free radical scavengers in myocardial ischemia.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Allopurinol; Cardiomyopathies; Catalase; Coronary Circulation; Epoprostenol; Free Radicals; Ibuprofen; Iloprost; Neutrophils; Oxygen; Pyrazoles; Pyrazolones; Superoxide Dismutase; Tiopronin | 1987 |
Myocardial ischaemia and reperfusion injury: reactive oxygen species and the role of neutrophil.
Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Epoprostenol; Free Radical Scavengers; Humans; Ibuprofen; Iloprost; Myocardial Ischemia; Myocardial Reperfusion Injury; Neutrophils; Prostaglandins E, Synthetic; Reactive Oxygen Species | 2005 |
33 other study(ies) available for ibuprofen and allopurinol
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Renal transport of organic compounds mediated by mouse organic anion transporter 3 (mOat3): further substrate specificity of mOat3.
Topics: Allopurinol; Animals; Biological Transport; Dose-Response Relationship, Drug; Female; Kidney; Male; Mice; Oocytes; Organic Anion Transporters, Sodium-Independent; Substrate Specificity; Xenopus laevis | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Synthesis and anti-inflammatory activity of novel biscoumarin-chalcone hybrids.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chalcone; Coumarins; Edema; Microsomes; Rats | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Comparison of the efficacy of mechanistically different antioxidants in the rat hemorrhagic shock model.
Topics: Animals; Antioxidants; Chromans; Deferoxamine; Disease Models, Animal; Ibuprofen; Lipid Peroxidation; Male; Oxypurinol; Piperazines; Pregnatrienes; Rats; Rats, Inbred Strains; Shock, Hemorrhagic; Vitamin E; Xanthine Oxidase | 1991 |
Identification and modifications of the pulmonary and systemic inflammatory and biochemical changes caused by a skin burn.
Topics: Allopurinol; Animals; Burns; Deferoxamine; Hemodynamics; Ibuprofen; Lipid Peroxidation; Liver; Lung; Malondialdehyde; Sheep | 1990 |
Early postburn lipid peroxidation: effect of ibuprofen and allopurinol.
Topics: Allopurinol; Animals; Burns; Disease Models, Animal; Edema; Ibuprofen; Inflammation; Lipid Peroxidation; Liver; Lung; Malondialdehyde; Neutrophils; Oxygen Consumption; Reference Values; Sheep | 1990 |
The beneficial effects of ibuprofen on a lethal live E. coli septic shock model and the relationship of these effects to superoxide radical production.
Topics: Animals; Dogs; Dopamine; Escherichia coli Infections; Fluid Therapy; Free Radicals; Hemodynamics; Ibuprofen; Lipid Peroxidation; Nitriles; Oxamic Acid; Sepsis; Shock, Septic; Superoxides; Tromethamine; Xanthine Oxidase | 1989 |
Effect of enzymatically generated reactive oxygen metabolites on the cyclic nucleotide content in isolated rat glomeruli.
Topics: Allopurinol; Animals; Cyclic AMP; Cyclic GMP; Dinoprostone; Histamine; Ibuprofen; Kidney Cortex; Kidney Glomerulus; Kidney Tubules; Kinetics; Meclofenamic Acid; Methysergide; Metiamide; Oxidation-Reduction; Prostaglandins E; Rats; Rats, Inbred Strains; Xanthine Oxidase | 1984 |
Prevention of postasphyxial increase in lipid peroxides and retinal function deterioration in the newborn pig by inhibition of cyclooxygenase activity and free radical generation.
Topics: Allopurinol; Animals; Animals, Newborn; Asphyxia; Dinoprost; Dinoprostone; Electroretinography; Free Radicals; Ibuprofen; Lipid Peroxides; Malondialdehyde; Retina; Swine | 1993 |
Role of xanthine oxidase and prostaglandins in inflammatory-induced bacterial translocation.
Topics: Allopurinol; Animals; Bacterial Physiological Phenomena; Enzyme Activation; Ibuprofen; Inflammation; Intestinal Mucosa; Lymph Nodes; Mice; Prostaglandins; Rats; Rats, Sprague-Dawley; Sodium Chloride; Xanthine Oxidase; Zymosan | 1993 |
Effects of allopurinol, ibuprofen and cyclosporin A on local microcirculatory disturbance due to burn injuries.
Topics: Allopurinol; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns; Cyclosporine; Disease Models, Animal; Enzyme Inhibitors; Ibuprofen; Immunosuppressive Agents; Injury Severity Score; Male; Microcirculation; Rats; Rats, Wistar; Skin | 1997 |
Long-term renal preservation and prevention of acute tubular necrosis by inhibition of arachidonate metabolism.
Topics: Adenosine; Allopurinol; Animals; Arachidonic Acid; Aspirin; Benzofurans; Dogs; Enzyme Inhibitors; Female; Glutathione; Ibuprofen; Imidazoles; Insulin; Kidney Transplantation; Kidney Tubular Necrosis, Acute; Kidney Tubules; Leukotriene Antagonists; Leukotrienes; Organ Preservation; Organ Preservation Solutions; Pyridines; Raffinose; Thromboxane-A Synthase | 1995 |
Rhinovirus-induced oxidative stress and interleukin-8 elaboration involves p47-phox but is independent of attachment to intercellular adhesion molecule-1 and viral replication.
Topics: Allopurinol; Catecholamines; Cells, Cultured; Humans; Ibuprofen; Imidazolines; Intercellular Adhesion Molecule-1; Interleukin-8; NADPH Oxidases; Oxidative Stress; Phosphoproteins; Rhinovirus; Superoxides; Virus Replication | 2000 |
Role of L-arginine in ibuprofen-induced oxidative stress and neutrophil infiltration in gastric mucosa.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Gastric Mucosa; Glutathione; Glutathione Peroxidase; Ibuprofen; Lipid Peroxidation; Male; Neutrophil Activation; Neutrophils; Oxidative Stress; Peroxidase; Protective Agents; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Time Factors; Xanthine Oxidase | 2004 |
Allopurinol/uricase and ibuprofen enhance engraftment of cardiomyocyte-enriched human embryonic stem cells and improve cardiac function following myocardial injury.
Topics: Acute Disease; Allopurinol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Combined Modality Therapy; Disease Models, Animal; Female; Fluorescent Antibody Technique; Heart; Humans; Ibuprofen; Mice; Mice, SCID; Microscopy, Confocal; Myocardial Ischemia; Myocytes, Cardiac; Stem Cell Transplantation; Stroke Volume; Urate Oxidase | 2006 |
In vitro drug-drug interaction studies with febuxostat, a novel non-purine selective inhibitor of xanthine oxidase: plasma protein binding, identification of metabolic enzymes and cytochrome P450 inhibition.
Topics: Blood Proteins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Febuxostat; Glucuronosyltransferase; Humans; Ibuprofen; In Vitro Techniques; Male; Microsomes, Liver; Protein Binding; Thiazoles; Warfarin; Xanthine Oxidase | 2008 |