ibuprofen and acetylcysteine

ibuprofen has been researched along with acetylcysteine in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.55)18.7374
1990's2 (9.09)18.2507
2000's7 (31.82)29.6817
2010's11 (50.00)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Bharate, SS; Vishwakarma, RA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Prescott, LF1
Cederlund, H; Mårdh, PA1
Ahmad, M; Li, WQ; Morin, I; Su, S; Zafarullah, M1
Beyreuther, K; Picard, MA; Uhrig, RK; Wiessler, M1
Araya, H; Hayashi, M; Tomita, M1
Bates, KA; Harvey, AR; Martins, RN1
del Prado, G; Huelves, L; Naves, P; Ponte, MC; Rodríguez-Cerrato, V; Ruiz, V; Soriano, F1
del Carmen Ponte, M; del Prado, G; Naves, P; Rodríguez-Cerrato, V; Ruiz, V; Soriano, F1
Osterhoudt, K; Selbst, SM1
Bouchet, LM; de la Guardia, M; Delgado-Pérez, T; Galian, RE; Pérez-Prieto, J1
Ghannoum, M; Gosselin, S; Grunbaum, AM; Kazim, S; Villeneuve, E1

Reviews

1 review(s) available for ibuprofen and acetylcysteine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

21 other study(ies) available for ibuprofen and acetylcysteine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
    Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7

    Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics

2015
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Clinical features and management of analgesic poisoning.
    Human toxicology, 1984, Volume: 3 Suppl

    Topics: Acetaminophen; Acetylcysteine; Analgesics; Analgesics, Opioid; Humans; Ibuprofen; Mefenamic Acid; Phenylbutazone; Salicylates

1984
Antimicrobial activities of N-acetylcysteine and some non-steroidal antiinflammatory drugs.
    The Journal of antimicrobial chemotherapy, 1993, Volume: 32, Issue:6

    Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Candida albicans; Escherichia coli; Humans; Ibuprofen; Infant, Newborn; Ketoprofen; Microbial Sensitivity Tests; Staphylococcus

1993
Induction of stromelysin gene expression by tumor necrosis factor alpha is inhibited by dexamethasone, salicylate, and N-acetylcysteine in synovial fibroblasts.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:3

    Topics: Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Cattle; Cells, Cultured; Dexamethasone; Fibroblasts; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Ibuprofen; Indomethacin; Matrix Metalloproteinase 3; Proline; Sodium Salicylate; Synovial Membrane; Thiocarbamates; Tissue Inhibitor of Metalloproteinase-3; Transcription Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha; Vitamin E

1999
Synthesis of antioxidative and anti-inflammatory drugs glucoconjugates.
    Carbohydrate research, 2000, Mar-24, Volume: 325, Issue:1

    Topics: Acetylcysteine; Anti-Inflammatory Agents; Antioxidants; Biological Availability; Gallic Acid; Gentisates; Glucosides; Glycoconjugates; Hydroxybenzoates; Ibuprofen; Magnetic Resonance Spectroscopy; Phenols; Sulfhydryl Compounds; Vitamin E

2000
The novel formulation design of self-emulsifying drug delivery systems (SEDDS) type O/W microemulsion III: the permeation mechanism of a poorly water soluble drug entrapped O/W microemulsion in rat isolated intestinal membrane by the Ussing chamber method
    Drug metabolism and pharmacokinetics, 2006, Volume: 21, Issue:1

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Membrane Permeability; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Diffusion Chambers, Culture; Drug Compounding; Drug Delivery Systems; Drug Design; Emulsions; Ibuprofen; In Vitro Techniques; Intestinal Mucosa; Male; Mass Spectrometry; Membranes; Micelles; Mucins; Permeability; Pharmaceutical Preparations; Rats; Rats, Sprague-Dawley; Taurocholic Acid

2006
Oxidative stress in a rat model of chronic gliosis.
    Neurobiology of aging, 2007, Volume: 28, Issue:7

    Topics: Acetylcysteine; Aldehydes; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Cells, Cultured; Chronic Disease; Disease Models, Animal; Embryo, Mammalian; Fetal Tissue Transplantation; Free Radical Scavengers; Glial Fibrillary Acidic Protein; Gliosis; Ibuprofen; Lipid Peroxidation; Oxidative Stress; Protein Carbonylation; Rats; Time Factors

2007
Effects of human serum albumin, ibuprofen and N-acetyl-L-cysteine against biofilm formation by pathogenic Escherichia coli strains.
    The Journal of hospital infection, 2010, Volume: 76, Issue:2

    Topics: Acetylcysteine; Anti-Bacterial Agents; Biofilms; Escherichia coli; Humans; Ibuprofen; Microbial Sensitivity Tests; Serum Albumin

2010
Biofilm formation by Streptococcus pneumoniae strains and effects of human serum albumin, ibuprofen, N-acetyl-l-cysteine, amoxicillin, erythromycin, and levofloxacin.
    Diagnostic microbiology and infectious disease, 2010, Volume: 67, Issue:4

    Topics: Acetylcysteine; Amoxicillin; Anti-Bacterial Agents; Biofilms; Erythromycin; Humans; Ibuprofen; Levofloxacin; Ofloxacin; Serum Albumin; Streptococcus pneumoniae

2010
Pediatric emergency medicine: legal briefs.
    Pediatric emergency care, 2012, Volume: 28, Issue:12

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aortic Aneurysm; Aortic Dissection; Appendicitis; Asthma; Child; Child, Preschool; Cystic Fibrosis; Diagnostic Errors; Drug Labeling; Drug Overdose; Emergencies; False Negative Reactions; Fatal Outcome; Female; Heart Rate, Fetal; Humans; Ibuprofen; Lymphoma, Non-Hodgkin; Male; Malpractice; Marfan Syndrome; Mediastinal Neoplasms; Medication Errors; Nuchal Cord; Patient Safety; Persistent Vegetative State; Pleurisy; Pregnancy; Respiratory Sounds; Social Media; Stevens-Johnson Syndrome; Suicide; Tomography, X-Ray Computed; Transportation of Patients; Unnecessary Procedures; Young Adult

2012
Sensing chiral drugs by using CdSe/ZnS nanoparticles capped with N-acetyl-L-cysteine methyl ester.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2013, Aug-12, Volume: 19, Issue:33

    Topics: Acetylcysteine; Cadmium Compounds; Circular Dichroism; Esters; Flurbiprofen; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Quantum Dots; Selenium Compounds; Spectrometry, Fluorescence; Stereoisomerism; Sulfides; Zinc Compounds

2013
Massive acetaminophen overdose: effect of hemodialysis on acetaminophen and acetylcysteine kinetics.
    Clinical toxicology (Philadelphia, Pa.), 2016, Volume: 54, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Acidosis, Lactic; Adolescent; Coma; Drug Overdose; Emergency Service, Hospital; Ethanol; Female; Half-Life; Humans; Ibuprofen; Lactic Acid; Liver; Renal Dialysis

2016