ibuprofen and acetic acid

ibuprofen has been researched along with acetic acid in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.33)18.7374
1990's0 (0.00)18.2507
2000's10 (41.67)29.6817
2010's9 (37.50)24.3611
2020's3 (12.50)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Caron, G; Ermondi, G1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bellman, K; Knegtel, RM; Settimo, L1
Fujimura, H; Hidaka, T; Hiramatsu, Y; Hosoe, K; Watanabe, K; Yamashita, T1
Connor, J; Makonnen, E; Rostom, A1
Dolezal, T; Krsiak, M1
Cauli, O; Cocco, MT; Congiu, C; Morelli, M; Onnis, V1
Alarcón de la Lastra, C; Bruseghini, L; Manuel Herrerias, J; Motilva, V; Sánchez-Fidalgo, S1
Bruseghini, L; Esteras, A; Illanes, M; Martín-Lacave, I; Motilva, V; Sánchez-Fidalgo, S1
Akhter, M; Khan, MS1
Jones, CK; Peters, SC; Shannon, HE1
Dolezal, T; Krsiak, M; Soukupova, M1
Dolezal, T; Krsiak, M; Sliva, J; Sykora, D; Vosmanska, M1
Janovsky, M; Krsiak, M1
Gin, KY; Nguyen, TV; Reinhard, M; Xu, Y1
Durga, KD; Mullangi, R; Padmavathi, Y; Reddy, BM; Venkatesh, S1
Ao, G; Cao, Q; Chen, D; Cui, J; Wu, D1
Fu, M; Huang, W; Pan, M; Qian, H; Wang, J; Yan, L1
Abdelhalim, MO; Elrokh, EM; Labib, DA; Osman, WA1
Achenbach, JC; Berrue, F; Ellis, LD; Hill, J; McDougall, JJ; Morash, M1
George, RF; Girgis, AS; Honkanadavar, HH; Panda, SS; Srour, AM1
Apotrosoaei, M; Buron, F; Butnaru, M; Constantin, S; Lupașcu, D; Lupușoru, CE; Profire, L; Routier, S; Taușer, RG; Vasincu, IM; Vereștiuc, L1
Abdelhameed, MF; Abdelnaser, A; Almalki, AJ; Bekheit, MS; Ghanim, AM; Girgis, AS; Ibrahim, TS; Kariuki, BM; Nasr, S; Panda, SS; Said, MF; Samir, N1

Other Studies

24 other study(ies) available for ibuprofen and acetic acid

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Analgesic and anti-inflammatory activities in rats of alpha-(3,5-di-t-butyl-4-hydroxybenzylidene)-gamma-butyrolactone (KME-4), and its intestinal damage.
    The Journal of pharmacy and pharmacology, 1986, Volume: 38, Issue:10

    Topics: 4-Butyrolactone; Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Capillary Permeability; Edema; Furans; Ibuprofen; Indomethacin; Intestinal Diseases; Lethal Dose 50; Male; Naproxen; Rats; Rats, Inbred Strains

1986
Comparison of analgesic effects of khat (Catha edulis Forsk) extract, D-amphetamine and ibuprofen in mice.
    The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:1

    Topics: Acetic Acid; Amphetamine; Analgesia; Analgesics; Animals; Catha; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Hot Temperature; Ibuprofen; Male; Mice; Pain; Plant Extracts

2000
Augmentation of analgesic effect of ibuprofen by alprazolam in experimental model of pain.
    Physiological research, 2002, Volume: 51, Issue:2

    Topics: Acetic Acid; Acute Disease; Administration, Oral; Alprazolam; Analgesics, Non-Narcotic; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; GABA Modulators; Ibuprofen; Male; Mice; Mice, Inbred Strains; Nociceptors; Pain; Receptors, GABA-A

2002
Synthesis of ibuprofen heterocyclic amides and investigation of their analgesic and toxicological properties.
    European journal of medicinal chemistry, 2003, Volume: 38, Issue:5

    Topics: Acetic Acid; Administration, Oral; Amides; Analgesics, Non-Narcotic; Animals; Ibuprofen; Injections, Intraperitoneal; Magnetic Resonance Spectroscopy; Male; Pain; Pain Measurement; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Spectrophotometry, Infrared; Stomach Ulcer; Structure-Activity Relationship

2003
COX expression and PGE(2) and PGD(2) production in experimental acute and chronic gastric lesions.
    International immunopharmacology, 2005, Volume: 5, Issue:2

    Topics: Acetic Acid; Acute Disease; Animals; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Hydrochloric Acid; Ibuprofen; Lactones; Male; Membrane Proteins; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Stomach Ulcer; Sulfones

2005
Administration of L-arginine reduces the delay of the healing process caused by ibuprofen. Implication of COX and growth factors expression.
    Histology and histopathology, 2005, Volume: 20, Issue:2

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Fibroblast Growth Factor 2; Growth Substances; Ibuprofen; Male; Membrane Proteins; Neovascularization, Pathologic; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Stomach Ulcer; Vascular Endothelial Growth Factor A; Wound Healing

2005
Synthesis, pharmacological activity and hydrolytic behavior of glyceride prodrugs of ibuprofen.
    European journal of medicinal chemistry, 2005, Volume: 40, Issue:4

    Topics: Acetic Acid; Analgesics; Animals; Glycerides; Hydrogen-Ion Concentration; Hydrolysis; Ibuprofen; Mice; Molecular Structure; Prodrugs; Rats; Ulcer

2005
Synergistic interactions between the dual serotonergic, noradrenergic reuptake inhibitor duloxetine and the non-steroidal anti-inflammatory drug ibuprofen in inflammatory pain in rodents.
    European journal of pain (London, England), 2007, Volume: 11, Issue:2

    Topics: Acetic Acid; Adrenergic Uptake Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Carrageenan; Drug Synergism; Duloxetine Hydrochloride; Hyperalgesia; Ibuprofen; Inflammation; Male; Mice; Mice, Inbred Strains; Norepinephrine; Pain; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Thiophenes

2007
Synergistic interaction between rilmenidine and ibuprofen in the writhing test in mice.
    Neuro endocrinology letters, 2009, Volume: 30, Issue:2

    Topics: Acetic Acid; Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Synergism; Ibuprofen; Male; Mice; Motor Activity; Oxazoles; Pain; Pain Measurement; Rilmenidine; Rotarod Performance Test

2009
Guaifenesin enhances the analgesic potency of ibuprofen, nimesulide and celecoxib in mice.
    Neuro endocrinology letters, 2009, Volume: 30, Issue:3

    Topics: Acetic Acid; Analgesia; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Synergism; Expectorants; Guaifenesin; Ibuprofen; Male; Mice; Pain; Pain Measurement; Pyrazoles; Sulfonamides

2009
Codeine did not increase analgesic efficacy of coxibs in contrast to that of paracetamol or ibuprofen: isobolographic analysis in mice.
    Neuro endocrinology letters, 2011, Volume: 32, Issue:2

    Topics: Acetaminophen; Acetic Acid; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Celecoxib; Codeine; Cyclooxygenase 2 Inhibitors; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Etoricoxib; Ibuprofen; Male; Mice; Mice, Inbred Strains; Models, Animal; Pain; Pyrazoles; Pyridines; Regression Analysis; Sulfonamides; Sulfones

2011
Photodegradation kinetics of p-tert-octylphenol, 4-tert-octylphenoxy-acetic acid and ibuprofen under simulated solar conditions in surface water.
    Chemosphere, 2011, Volume: 85, Issue:5

    Topics: Acetic Acid; Analgesics, Non-Narcotic; Humic Substances; Hydrogen Peroxide; Hydroxyl Radical; Ibuprofen; Kinetics; Phenols; Photolysis; Sunlight; Surface-Active Agents; Water

2011
Influence of piperine on ibuprofen induced antinociception and its pharmacokinetics.
    Arzneimittel-Forschung, 2011, Volume: 61, Issue:9

    Topics: Acetic Acid; Alkaloids; Analgesics; Animals; Benzodioxoles; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Enzyme Inhibitors; Formaldehyde; Fruit; Ibuprofen; Indicators and Reagents; Male; Mice; Pain Measurement; Piper nigrum; Piperidines; Polyunsaturated Alkamides

2011
In vitro and in vivo evaluation of ibuprofen-paeonol conjugate.
    Journal of controlled release : official journal of the Controlled Release Society, 2011, Nov-30, Volume: 152 Suppl 1

    Topics: Acetic Acid; Acetophenones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cytoprotection; Dinoprostone; Disease Models, Animal; Drug Combinations; Drug Compounding; Drug Stability; Edema; Esterification; Gastric Mucosa; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Ibuprofen; Injections, Intravenous; Intestinal Absorption; Magnetic Resonance Spectroscopy; Malondialdehyde; Mice; Nitric Oxide; Pain; Particle Size; Protective Agents; Rats; Stomach; Technology, Pharmaceutical; Xylenes

2011
Design, synthesis and biological evaluation of novel analgesic agents targeting both cyclooxygenase and TRPV1.
    Bioorganic & medicinal chemistry, 2016, Feb-15, Volume: 24, Issue:4

    Topics: Acetic Acid; Administration, Oral; Analgesics; Animals; Body Temperature; Capsaicin; Cyclooxygenase 1; Cyclooxygenase 2; Diamines; Drug Design; Gene Expression; Humans; Ibuprofen; Male; Mice; Nociception; Pain; Piperazines; Recombinant Proteins; Sheep; Structure-Activity Relationship; TRPV Cation Channels

2016
Synergistic analgesic, anti-pyretic and anti-inflammatory effects of extra virgin olive oil and ibuprofen in different experimental models of albino mice.
    International journal of rheumatic diseases, 2017, Volume: 20, Issue:10

    Topics: Acetic Acid; Albinism; Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Carrageenan; Dinoprostone; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Edema; Fever; Ibuprofen; Interferon-gamma; Male; Mice; Neutrophils; Olive Oil; Pain; Peritonitis; Saccharomyces cerevisiae; Time Factors

2017
Comparison of cannabinoids with known analgesics using a novel high throughput zebrafish larval model of nociception.
    Behavioural brain research, 2018, Jan-30, Volume: 337

    Topics: Acetaminophen; Acetic Acid; Analgesics; Animals; Cannabinoid Receptor Agonists; Cannabinoids; Disease Models, Animal; Dose-Response Relationship, Drug; Dronabinol; Ibuprofen; Larva; Locomotion; Nociception; Pain; Principal Component Analysis; Time Factors; Tramadol; Zebrafish

2018
Synthesis of new ibuprofen hybrid conjugates as potential anti-inflammatory and analgesic agents.
    Future medicinal chemistry, 2020, Volume: 12, Issue:15

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Edema; Humans; Ibuprofen; Molecular Structure; Pain; Pain Measurement; Quantitative Structure-Activity Relationship; Rats; Stomach Ulcer

2020
New ibuprofen derivatives with thiazolidine-4-one scaffold with improved pharmaco-toxicological profile.
    BMC pharmacology & toxicology, 2021, 02-04, Volume: 22, Issue:1

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cell Survival; Edema; Hot Temperature; Ibuprofen; Lethal Dose 50; Mice; Pain; Rats, Wistar; Thiazolidines

2021
Design and synthesis of ibuprofen-quinoline conjugates as potential anti-inflammatory and analgesic drug candidates.
    Bioorganic chemistry, 2022, Volume: 119

    Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cytokines; Dose-Response Relationship, Drug; Drug Design; Ibuprofen; Inflammation; Lipopolysaccharides; Mice; Molecular Structure; Nitric Oxide; Pain; Quantitative Structure-Activity Relationship; Quinolines; RAW 264.7 Cells

2022