ibuprofen and 6-ketoprostaglandin f1 alpha

ibuprofen has been researched along with 6-ketoprostaglandin f1 alpha in 78 studies

Research

Studies (78)

Timeframe	Studies, this research(%)	All Research%
pre-1990	54 (69.23)	18.7374
1990's	19 (24.36)	18.2507
2000's	4 (5.13)	29.6817
2010's	1 (1.28)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Abe, K; Akiu, N; Saito, T; Sato, M; Takeuchi, K; Yasujima, M; Yoshinaga, K	1
Byrick, RJ; Mullen, JB; Wigglesworth, DF; Wong, PY	1
Bernard, GR; Hardie, WD; Swindell, BB; Wheeler, AP; Wright, PW	1
Flynn, JF; Gore, DC; Griffin, MP; Herndon, DN; Lobe, TE; Traber, DL	1
Cashman, SJ; Dollery, CT; Fuller, RW; Rees, AJ; Ritter, JM; Ward, PS	1
Hudson, JC; Kane, FR; Mackey, WC; O'Donnel, TF; Su, YF; Watkins, WD; Wurm, WH	1
Baum, TD; Feldman, HS; Fink, MP; Heard, SO; Latka, CA	1
Brezinski, ME; Gimbrone, MA; Nicolaou, KC; Serhan, CN	1
Kadowitz, PJ; Mayeux, PR; McNamara, DB	1
Cohn, SM; Deniz, YF; Fink, MP; Lee, PC; Rothschild, HR; Wang, HL	1
Hechtman, HB; Klausner, JM; Kobzik, L; Paterson, IS; Rodzen, C; Shepro, D; Valeri, CR	1
Chyatte, D	1
Bernard, GR; Wright, PE	1
Arosio, E; Capuzzo, MG; Corsato, M; Dalla Riva, A; Degan, M; Lechi, A; Lechi, C; Minuz, P; Velo, GP	1
Jung, TT	1
Andresen, PJ; Chacho, KJ; Chacho, MS; Scommegna, A	1
Barsacchi, R; De Caterina, R; Giannessi, D; Lazzerini, G; Nanni, N; Pelosi, G	1
Johnson, A; Malik, AB; Perlman, MB	1
Daskalopoulos, G; Gentilini, P; Hsueh, W; Kronborg, I; Laffi, G; Zipser, RD	1
Kothari, HV; Ku, EC; Lee, W; Scholer, DW	1
Karmazyn, M	2
Hirsch, JI; Hirsh, PD; Lee, CC; Sugerman, HJ; Tatum, JL; Wright, TP	1
Needleman, P; Tripp, CS; Unanue, ER; Wyche, A	1
Brigham, KL; Ogletree, ML; Snapper, JR	1
Anderson, WP; Bobik, A	1
Bjornson, AB; Bjornson, HS; Knippenberg, RW	1
Bruck, DC; Lemen, RJ; Magarelli, JL; Quan, SF; Sobonya, RE; Witten, ML	1
Wang, ZG; Zhou, BT; Zhou, YG	1
Breslow, MJ; Miller, CF; Nishijima, MK; Traystman, RJ	1
Angelini, M; Baldini, L; Barenghi, L; Borsa, M; Carrabba, M; Ceriotti, F; Malandrino, S; Tonon, GC	1
Demling, R; Katz, A; Lalonde, C; Ryan, P; West, K	1
Campese, V; Horton, R; McKay, M; Nadler, JL; Vrbanac, J	1
Brigham, KL; Butka, BJ; Newman, JH	1
Burke, J; Hales, C; Jung, W; Shinozawa, Y	1
Jalovaara, P; Kairaluoma, M; Kiviniemi, H; Laitinen, S; Rämö, J; Ståhlberg, M; Viinikka, L	1
Blocher, CR; Harvey, CF; Lee, EC; Sielaff, TD; Sugerman, HJ; Tatum, JL	1
Anner, H; Hechtman, HB; Kaufman, RP; Kobzik, L; Shepro, D; Valeri, CR	1
Demling, RH; Lalonde, C	1
Fink, MP; Nelson, R; Roethel, R	1
Cook, JA; Halushka, PV; Knapp, RG; Wise, WC	1
Demling, RH; Hechtman, H; Wenger, H; Wong, C	1
Bellanti, JA; Cerquetti, MC; el-Tawil, G; Hooke, AM; Ramwell, PW; Sordelli, DO	1
Bruss, ML; Emau, P; Giri, SN; Zia, S	1
Beyers, BJ; Bowen, RJ; Longenecker, GL; Shah, AK; Swift, IA	1
Demling, RH; Wenger, H; Wong, C	1
Alexander, F; Hechtman, HB; Kobzik, L; Lelcuk, S; Shepro, D; Valeri, CR	1
Farias, LR; Frey, CF; Gunther, R; Holcroft, JW	1
Ferrier, GR; Karmazyn, M; Moffat, MP	1
Kimble, EF; Kothari, HV; Ku, EC; Lee, W; Liauw, L; Tjan, J	1
Coleman, JH; Greenblatt, DJ; Jones, KJ; Levine, PH; Orsulak, PJ; Peterson, M; Schildkraut, JJ; Sheehan, DV; Uzogara, E; Watkins, D	1
Downie, JW; Karmazyn, M	1
Barsotti, P; Ciabattoni, G; Cinotti, GA; Manzi, M; Patrono, C; Pecci, G; Pierucci, A; Pugliese, F; Simonetti, BM; Taggi, F	1
Hill, RD; Hüttemeier, PC; Kong, D; Schuette, AH; Watkins, WD; Wonders, TR; Zapol, WM	1
Casey, LC; Fink, MP; MacVittie, TJ	1
Brigham, KL; Hutchison, AA; Ogletree, ML; Snapper, JR	1
Ehrlich, HP	1
Dunham, B; Hechtman, HB; Krausz, MM; Levine, L; Shepro, D; Utsunomiya, T; Valeri, CR	1
Cook, JA; Halushka, PV; Wise, WC	1
Czervionke, RL; Hoak, JC; Parks, WM	1
Dunham, B; Hechtman, HB; Krausz, MM; Levine, LL; Shepro, D; Utsunomiya, T	1
Blower, P; Melarange, R; Spangler, R	1
Arosio, E; Campedelli, A; Degan, M; Lechi, A; Minuz, P; Pancera, P; Priante, F; Ribul, M	1
Altman, JD; Bache, RJ	1
Cole, DJ; Drummond, JC; Kalkman, CJ; Patel, PM; Sano, T; Yaksh, TL	1
Collins, JN; Fletcher, JR; Graves, ED; Izenberg, SD; Luterman, A; Rodning, CB; Williams, MD	1
Arosio, E; Lechi, A; Minuz, P; Pancera, P; Pirante, F; Ribul, M	1
Leffler, CW; Parfenova, H	1
Brinkmann, A; Brückner, U; Büchler, M; Georgieff, M; Kneitinger, E; Radermacher, P; Rockemann, M; Seeling, W; Vogeser, F; Wolf, CF	1
Danon, A; Even, L; Hochberg, Z	1
Catella-Lawson, F; FitzGerald, GA; Kapoor, S; Lawson, JA; Mardini, IA; McAdam, BF	1
Dirig, DM; Yaksh, TL	1
Bailey, SR; Elliott, J	1
Schrör, K; Weber, A; Yildirim, H	1
Irisawa, T; Kuwagata, Y; Matsuyama, S; Nakamori, Y; Oda, J; Sugimoto, H; Takahashi, M	1
Fitzgerald, D; McCrory, C	1
Abad-Santos, M; Abad-Santos, P; Aranda, JV; Beharry, KD; Gharraee, Z; Hasan, J; Modanlou, HD; Stavitsky, Y	1
De la Cruz, JP; Gonzalez-Correa, JA; Jebrouni, N; Lopez-Villodres, JA; Reyes, JJ; Ruiz-Moreno, MI	1

Trials

9 trial(s) available for ibuprofen and 6-ketoprostaglandin f1 alpha

Article	Year
Ibuprofen pretreatment inhibits prostacyclin release during abdominal exploration in aortic surgery. Anesthesiology, 1990, Volume: 72, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Abdomen; Adult; Aged; Aorta; Double-Blind Method; Epoprostenol; Female; Flushing; Hemodynamics; Humans; Ibuprofen; Male; Middle Aged; Premedication; Prospective Studies; Randomized Controlled Trials as Topic; Thromboxane B2	1990
Effects of suprofen on renal function in patients with rheumatoid arthritis. International journal of clinical pharmacology research, 1987, Volume: 7, Issue:4 Topics: 6-Ketoprostaglandin F1 alpha; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Dinoprost; Double-Blind Method; Female; Humans; Ibuprofen; Kidney; Male; Middle Aged; Phenylpropionates; Prostaglandins F; Random Allocation; Suprofen	1987
Kinetics of ibuprofen effect on platelet and endothelial prostanoid release. Clinical pharmacology and therapeutics, 1985, Volume: 37, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Adult; Blood Platelets; Dose-Response Relationship, Drug; Double-Blind Method; Epoprostenol; Female; Humans; Ibuprofen; Kinetics; Male; Radioimmunoassay; Random Allocation; Thromboxane A2; Thromboxane B2; Time Factors	1985
Some biochemical correlates of panic attacks with agoraphobia and their response to a new treatment. Journal of clinical psychopharmacology, 1984, Volume: 4, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Adult; Agoraphobia; Alprazolam; Anti-Anxiety Agents; Benzodiazepines; beta-Thromboglobulin; Blood Platelets; Fear; Female; Humans; Ibuprofen; Male; Methoxyhydroxyphenylglycol; Middle Aged; Monoamine Oxidase; Panic; Phobic Disorders; Platelet Factor 4; Psychological Tests; Thromboxane B2	1984
Effects of sulindac and ibuprofen in patients with chronic glomerular disease. Evidence for the dependence of renal function on prostacyclin. The New England journal of medicine, 1984, Feb-02, Volume: 310, Issue:5 Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Aged; Chronic Disease; Creatinine; Dinoprostone; Epoprostenol; Female; Glomerular Filtration Rate; Glomerulonephritis; Humans; Ibuprofen; Indenes; Kidney; Kidney Glomerulus; Middle Aged; p-Aminohippuric Acid; Prostaglandins E; Renal Circulation; Sulindac	1984
Amlodipine and haemodynamic effects of cyclo-oxygenase inhibition. British journal of clinical pharmacology, 1995, Volume: 39, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aldosterone; Amlodipine; Biomarkers; Blood Pressure; Creatinine; Cross-Over Studies; Cyclooxygenase Inhibitors; Epoprostenol; Heart Rate; Hemodynamics; Humans; Hypertension; Ibuprofen; Male; Middle Aged; Outpatients; Renin; Single-Blind Method; Thromboxane A2; Ultrasonography; Vascular Resistance; Vasodilator Agents	1995
Changes in peripheral hemodynamics and vasodilating prostaglandins after high-dose short-term ibuprofen in chronically treated hypertensive patients. Prostaglandins, leukotrienes, and essential fatty acids, 1996, Volume: 54, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cyclooxygenase Inhibitors; Epoprostenol; Heart Function Tests; Heart Rate; Humans; Hypertension; Ibuprofen; Lisinopril; Male; Middle Aged; Prostaglandins; Thromboxane A2; Thromboxane B2; Vasodilator Agents	1996
The impact of prostanoids on pulmonary gas exchange during abdominal surgery with mesenteric traction. Anesthesia and analgesia, 1997, Volume: 85, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Abdominal; Cyclooxygenase Inhibitors; Dinoprostone; Double-Blind Method; Epoprostenol; Female; Humans; Ibuprofen; Injections, Intravenous; Intraoperative Care; Male; Mesentery; Middle Aged; Oxygen; Pancreatectomy; Placebos; Prospective Studies; Prostaglandins; Pulmonary Gas Exchange; Pulmonary Veins; Thromboxane B2; Traction	1997
Spinal prostaglandin formation and pain perception following thoracotomy: a role for cyclooxygenase-2. Chest, 2004, Volume: 125, Issue:4 Topics: 6-Ketoprostaglandin F1 alpha; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Ibuprofen; Isoenzymes; Pain, Postoperative; Perception; Pneumonectomy; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Spinal Cord; Sulfonamides; Thoracotomy	2004

Other Studies

69 other study(ies) available for ibuprofen and 6-ketoprostaglandin f1 alpha

Article	Year
Effect of sulindac on prostaglandin synthesis in human and in cultured rat renal and vascular smooth muscle cells. The Tohoku journal of experimental medicine, 1992, Volume: 166, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Animals; Arachidonic Acids; Cells, Cultured; Creatinine; Diclofenac; Dinoprostone; Female; Humans; Ibuprofen; Kidney; Kidney Glomerulus; Male; Middle Aged; Muscle, Smooth, Vascular; Prostaglandins; Rats; Rats, Sprague-Dawley; Sulindac	1992
Ibuprofen pretreatment does not prevent hemodynamic instability after cemented arthroplasty in dogs. Anesthesia and analgesia, 1992, Volume: 75, Issue:4 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arthroplasty; Dogs; Embolism, Fat; Hemodynamics; Ibuprofen; Infusions, Intravenous; Thromboxane B2	1992
Effect of cyclooxygenase inhibition on amphotericin B-induced lung injury in awake sheep. The Journal of infectious diseases, 1992, Volume: 166, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Amphotericin B; Animals; Body Temperature; Ibuprofen; Infusions, Intravenous; Leukocyte Count; Lung; Lung Compliance; Pulmonary Ventilation; Pulmonary Wedge Pressure; Sheep; Thromboxane B2	1992
Ibuprofen therapy in experimental porcine gram-negative septic shock. Resuscitation, 1991, Volume: 22, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Escherichia coli Infections; Ibuprofen; Leukocyte Count; Peritonitis; Platelet Count; Pulmonary Circulation; Shock, Septic; Swine; Thromboxane B2; Vascular Resistance	1991
Excretion of metabolites of prostacyclin and thromboxane by rats with nephrotoxic nephritis: effects of interleukin-1. British journal of pharmacology, 1991, Volume: 103, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Creatinine; Cyclooxygenase Inhibitors; Epoprostenol; Ibuprofen; In Vitro Techniques; Interleukin-1; Kidney Glomerulus; Male; Nephritis; Neutrophils; Rats; Rats, Inbred Strains; Thromboxane B2; Thromboxanes	1991
Endotoxin-induced myocardial depression in rats: effect of ibuprofen and SDZ 64-688, a platelet activating factor receptor antagonist. The Journal of surgical research, 1990, Volume: 48, Issue:6 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Body Weight; Depression, Chemical; Endotoxins; Escherichia coli; Heart Rate; Ibuprofen; In Vitro Techniques; Lipopolysaccharides; Male; Myocardial Contraction; Platelet Activating Factor; Rats; Rats, Inbred Strains	1990
Lipoxins stimulate prostacyclin generation by human endothelial cells. FEBS letters, 1989, Mar-13, Volume: 245, Issue:1-2 Topics: 6-Ketoprostaglandin F1 alpha; Calcimycin; Cells, Cultured; Chromatography, High Pressure Liquid; Endothelium, Vascular; Epoprostenol; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Kinetics; Lipoxins; SRS-A; Umbilical Veins	1989
Differential effects of ibuprofen, indomethacin, and meclofenamate on prostaglandin endoperoxide H2 metabolism. Molecular and cellular biochemistry, 1989, May-04, Volume: 87, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cats; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Ibuprofen; In Vitro Techniques; Indomethacin; Intramolecular Oxidoreductases; Isomerases; Lung; Meclofenamic Acid; Microsomes; ortho-Aminobenzoates; Prostaglandin Antagonists; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandin-E Synthases; Prostaglandins H; Thromboxane-A Synthase	1989
Systemic and mesenteric O2 metabolism in endotoxic pigs: effect of ibuprofen and meclofenamate. Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 67, Issue:5 Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Animals; Cyclooxygenase Inhibitors; Endotoxins; Hemodynamics; Hydrogen-Ion Concentration; Ibuprofen; Lipopolysaccharides; Male; Meclofenamic Acid; Mesentery; ortho-Aminobenzoates; Oxygen; Shock, Septic; Swine; Thromboxane B2	1989
Vasodilating prostaglandins attenuate ischemic renal injury only if thromboxane is inhibited. Annals of surgery, 1989, Volume: 209, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Acute Kidney Injury; Animals; Creatinine; Disease Models, Animal; Drug Combinations; Drug Evaluation, Preclinical; Epoprostenol; Ibuprofen; Ischemia; Kidney; Male; Organ Size; Prostaglandins E; Rats; Rats, Inbred Strains; Thromboxane B2; Vasodilator Agents	1989
Prevention of chronic cerebral vasospasm in dogs with ibuprofen and high-dose methylprednisolone. Stroke, 1989, Volume: 20, Issue:8 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprost; Dinoprostone; Dogs; Ibuprofen; Ischemic Attack, Transient; Methylprednisolone; Subarachnoid Hemorrhage; Thromboxane B2	1989
Mechanisms of late hemodynamic and airway dynamic responses to endotoxin in awake sheep. The American review of respiratory disease, 1989, Volume: 140, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Airway Resistance; Animals; Atropine; Blood Pressure; Endotoxins; Hemodynamics; Ibuprofen; Lung; Lung Compliance; Metaproterenol; Propranolol; Pulmonary Circulation; Pulmonary Gas Exchange; Respiratory Physiological Phenomena; Respiratory System; Sheep; Thromboxane B2	1989
Antihypertensive activity of enalapril. Effect of ibuprofen and different salt intakes. Journal of clinical hypertension, 1987, Volume: 3, Issue:4 Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Enalapril; Humans; Hypertension; Ibuprofen; Kallikreins; Male; Middle Aged; Renin; Sodium, Dietary	1987
Prostaglandins, leukotrienes, and other arachidonic acid metabolites in the pathogenesis of otitis media. The Laryngoscope, 1988, Volume: 98, Issue:9 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Chinchilla; Dinoprostone; Disease Models, Animal; Humans; Hydrocortisone; Hydroxyeicosatetraenoic Acids; Ibuprofen; Leukotriene B4; Middle Ear Ventilation; Otitis Media with Effusion; Penicillin G; Prostaglandins; Prostaglandins E; SRS-A; Temporal Bone; Thromboxane B2	1988
Peritoneal fluid in patients with and without endometriosis: prostanoids and macrophages and their effect on the spermatozoa penetration assay. American journal of obstetrics and gynecology, 1986, Volume: 154, Issue:6 Topics: 6-Ketoprostaglandin F1 alpha; Acid Phosphatase; Ascitic Fluid; Cell Count; Dinoprost; Endometriosis; Female; Humans; Ibuprofen; Infertility, Female; Laparoscopy; Macrophage Activation; Macrophages; Male; Menstrual Cycle; Prostaglandins E; Prostaglandins F; Radioimmunoassay; Sperm-Ovum Interactions; Thromboxane B2	1986
Characteristics of thromboxane production by the isolated-perfused rat heart. Advances in prostaglandin, thromboxane, and leukotriene research, 1987, Volume: 17A Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Heart; Ibuprofen; In Vitro Techniques; Methacrylates; Myocardium; Perfusion; Rats; Thromboxane B2	1987
Ibuprofen prevents thrombin-induced lung vascular injury: mechanism of effect. The American journal of physiology, 1987, Volume: 252, Issue:3 Pt 2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cell Adhesion; Cyclooxygenase Inhibitors; Drug Interactions; Ibuprofen; Lymphatic System; Lymphocyte Activation; Meclofenamic Acid; Neutrophils; Pulmonary Circulation; Pulmonary Embolism; Sheep; Superoxides; Thrombin; Thromboxane B2; Vascular Resistance	1987
Effects of sulindac and ibuprofen in patients with cirrhosis and ascites. An explanation for the renal-sparing effect of sulindac. Gastroenterology, 1986, Volume: 90, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Adult; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Ibuprofen; Indenes; Kidney; Kidney Function Tests; Liver Cirrhosis, Alcoholic; Middle Aged; Prostaglandins E; Renal Circulation; Sulindac; Thromboxane B2; Time Factors	1986
Effect of diclofenac sodium on the arachidonic acid cascade. The American journal of medicine, 1986, Apr-28, Volume: 80, Issue:4B Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Leukocytes; Lipoxygenase Inhibitors; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Naproxen; Phospholipids; Piroxicam; Prostaglandins E; Rats; SRS-A; Thiazines; Triglycerides	1986
Contribution of prostaglandins to reperfusion-induced ventricular failure in isolated rat hearts. The American journal of physiology, 1986, Volume: 251, Issue:1 Pt 2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Coronary Circulation; Coronary Disease; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Epoprostenol; Ibuprofen; Indomethacin; Male; Myocardial Contraction; Myocardium; Perfusion; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains	1986
Effects of ibuprofen on a pig Pseudomonas ARDS model. The Journal of surgical research, 1986, Volume: 40, Issue:5 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Disease Models, Animal; Ibuprofen; Oxygen; Pseudomonas Infections; Pulmonary Artery; Pulmonary Wedge Pressure; Radioimmunoassay; Respiratory Distress Syndrome; Swine; Thromboxane B2	1986
The functional significance of the regulation of macrophage Ia expression by endogenous arachidonate metabolites in vitro. Journal of immunology (Baltimore, Md. : 1950), 1986, Dec-15, Volume: 137, Issue:12 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; Female; Histocompatibility Antigens Class II; Ibuprofen; Indomethacin; Macrophage Activation; Macrophages; Mice; Mice, Inbred Strains; Prostaglandins E; SRS-A; Thromboxanes	1986
Calcium paradox-evoked release of prostacyclin and immunoreactive leukotriene C4 from rat and guinea-pig hearts. Evidence that endogenous prostaglandins inhibit leukotriene biosynthesis. Journal of molecular and cellular cardiology, 1987, Volume: 19, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Epoprostenol; Guinea Pigs; Heart; Ibuprofen; In Vitro Techniques; Male; Myocardial Contraction; Perfusion; Rats; Rats, Inbred Strains; SRS-A	1987
Direct and indirect effects of leukotriene D4 on the lungs of unanesthetized sheep. Respiration; international review of thoracic diseases, 1987, Volume: 51, Issue:4 Topics: 6-Ketoprostaglandin F1 alpha; Anesthesia; Animals; Arachidonate 5-Lipoxygenase; Blood Pressure; Female; Hypertension, Pulmonary; Ibuprofen; Imidazoles; Lung; Lung Compliance; Lymph; Male; Meclofenamic Acid; Prostaglandin-Endoperoxide Synthases; Pulmonary Wedge Pressure; Sheep; SRS-A; Thromboxane B2; Thromboxane-A Synthase	1987
Effects of five non-steroidal anti-inflammatory drugs on the renal and systemic responses to arachidonate in conscious dogs. Clinical and experimental pharmacology & physiology, 1987, Volume: 14, Issue:8 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Aspirin; Dinoprostone; Dogs; Ibuprofen; Indomethacin; Kidney; Kidney Cortex; Microsomes; Phenylbutazone; Prostaglandins; Prostaglandins E; Sulindac	1987
Nonsteroidal anti-inflammatory drugs correct the bactericidal defect of polymorphonuclear leukocytes in a guinea pig model of thermal injury. The Journal of infectious diseases, 1988, Volume: 157, Issue:5 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Bactericidal Activity; Blood Cell Count; Burns; Complement System Proteins; Concanavalin A; Cyclooxygenase Inhibitors; Disease Models, Animal; Guinea Pigs; Ibuprofen; Indomethacin; Kinetics; Lymphocyte Activation; Neutrophils; Phagocytosis; Piroxicam; Pseudomonas aeruginosa; Spleen; Thromboxane B2	1988
Acute cigarette smoke exposure causes lung injury in rabbits treated with ibuprofen. Experimental lung research, 1987, Volume: 13, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Female; Ibuprofen; Lung; Lung Diseases; Male; Nicotiana; Organometallic Compounds; Pentetic Acid; Plants, Toxic; Pulmonary Alveoli; Pulmonary Edema; Rabbits; Smoke; Technetium; Technetium Tc 99m Pentetate; Thromboxane B2; Time Factors	1987
[Protective effect of PGI2 on experimental ARDS and factors influencing it]. Zhonghua wai ke za zhi [Chinese journal of surgery], 1987, Volume: 25, Issue:12 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Epoprostenol; Ibuprofen; Male; Oleic Acids; Rabbits; Respiratory Distress Syndrome; Thromboxane B2	1987
Effect of naloxone and ibuprofen on organ blood flow during endotoxic shock in pig. The American journal of physiology, 1988, Volume: 255, Issue:1 Pt 2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Hemodynamics; Ibuprofen; Microspheres; Naloxone; Regional Blood Flow; Shock, Septic; Swine; Thromboxane B2	1988
Topical ibuprofen decreases thromboxane release from the endotoxin-stimulated burn wound. The Journal of trauma, 1986, Volume: 26, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Administration, Topical; Animals; Blood Pressure; Burns; Endotoxins; Escherichia coli; Ibuprofen; Infusions, Parenteral; Lymph; Ointments; Oxygen; Skin Absorption; Thromboxane B2; Thromboxanes	1986
Evidence that prostacyclin modulates the vascular actions of calcium in man. The Journal of clinical investigation, 1986, Volume: 77, Issue:4 Topics: 6-Ketoprostaglandin F1 alpha; Blood Pressure; Calcium; Creatinine; Dinoprostone; Drug Interactions; Epoprostenol; Hemodynamics; Humans; Ibuprofen; Indomethacin; Kidney; Natriuresis; Nifedipine; Potassium; Prazosin; Prostaglandins E; Regional Blood Flow; Sulindac; Vascular Resistance; Vasodilation	1986
Thromboxane A2 and prostacyclin do not modulate pulmonary hemodynamics during exercise in sheep. Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 61, Issue:5 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Cardiac Output; Epoprostenol; Hemodynamics; Hypoxia; Ibuprofen; Imidazoles; Lung; Lymph; Meclofenamic Acid; Physical Exertion; Pulmonary Artery; Sheep; Thromboxane A2; Vascular Resistance	1986
Ibuprofen prevents synthetic smoke-induced pulmonary edema. The American review of respiratory disease, 1986, Volume: 134, Issue:6 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Drug Evaluation, Preclinical; Epoprostenol; Germ-Free Life; Hemodynamics; Hydrochloric Acid; Ibuprofen; Indomethacin; Lung; Male; Pulmonary Edema; Rats; Rats, Inbred Strains; Smoke; Thromboxane B2	1986
Prostacyclin and thromboxane in acute hemorrhagic pancreatitis in dogs. The Journal of surgical research, 1987, Volume: 42, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Blood Pressure; Dogs; Epoprostenol; Hemorrhage; Ibuprofen; Pancreatitis; Thromboxane B2	1987
Ibuprofen and methylprednisolone in a pig Pseudomonas ARDS model. Circulatory shock, 1987, Volume: 21, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Capillary Permeability; Disease Models, Animal; Hemodynamics; Ibuprofen; Methylprednisolone; Pseudomonas Infections; Respiratory Distress Syndrome; Swine; Thromboxane B2	1987
A high plasma prostaglandin to thromboxane ratio protects against renal ischemia. Surgery, gynecology & obstetrics, 1987, Volume: 165, Issue:5 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzofurans; Creatinine; Evaluation Studies as Topic; Ibuprofen; Imidazoles; Ischemia; Kidney; Kidney Tubular Necrosis, Acute; Male; Methacrylates; Pyridines; Rats; Thromboxane B2; Thromboxane-A Synthase	1987
Topical ibuprofen decreases early postburn edema. Surgery, 1987, Volume: 102, Issue:5 Topics: 6-Ketoprostaglandin F1 alpha; Administration, Topical; Animals; Burns; Edema; Ibuprofen; Lymph; Prostaglandin Antagonists; Prostaglandins; Sheep; Thromboxane B2	1987
Low-dose dopamine preserves renal blood flow in endotoxin shocked dogs treated with ibuprofen. The Journal of surgical research, 1985, Volume: 38, Issue:6 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Diuresis; Dogs; Dopamine; Female; Hemodynamics; Ibuprofen; Infusions, Parenteral; Male; Radioimmunoassay; Renal Circulation; Shock, Septic; Thromboxane B2	1985
Ibuprofen, methylprednisolone, and gentamicin as conjoint therapy in septic shock. Circulatory shock, 1985, Volume: 17, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Disease Models, Animal; Drug Therapy, Combination; Female; Gentamicins; Ibuprofen; Indomethacin; Methylprednisolone; Peritonitis; Rats; Shock, Septic; Thromboxane B2	1985
Role of subcutaneous tissue endotoxin in the production of prostanoid-induced lung injury: comparison with intravenous endotoxin response. Circulatory shock, 1985, Volume: 17, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Endotoxins; Ibuprofen; Injections, Intravenous; Injections, Subcutaneous; Lung; Lung Injury; Lymph; Prostaglandins; Sheep; Thromboxane B2	1985
Ibuprofen modifies the inflammatory response of the murine lung to Pseudomonas aeruginosa. European journal of respiratory diseases, 1985, Volume: 67, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprostone; Disease Models, Animal; Ibuprofen; Inflammation; Kinetics; Lung; Male; Mice; Neutrophils; Pneumonia; Prostaglandins E; Pseudomonas Infections; Therapeutic Irrigation; Thromboxane B2	1985
Ibuprofen prevents Pasteurella hemolytica endotoxin-induced changes in plasma prostanoids and serotonin, and fever in sheep. Journal of veterinary pharmacology and therapeutics, 1985, Volume: 8, Issue:4 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprost; Endotoxins; Female; Fever; Ibuprofen; Pasteurella; Pasteurella Infections; Prostaglandins; Prostaglandins F; Serotonin; Sheep; Sheep Diseases; Thromboxane B2; Thromboxanes	1985
Pulmonary dysfunction secondary to soft-tissue endotoxin. Archives of surgery (Chicago, Ill. : 1960), 1985, Volume: 120, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Endotoxins; Escherichia coli; Hypertension, Pulmonary; Hypoxia; Ibuprofen; Lung; Lung Diseases; Lymph; Lymphatic System; Muscles; Sheep; Thromboxane B2	1985
Prostacyclin and thromboxane A2 moderate postischemic renal failure. Surgery, 1985, Volume: 98, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Acute Kidney Injury; Animals; Epoprostenol; Ibuprofen; Ischemia; Male; Methacrylates; Premedication; Rats; Renal Circulation; Thromboxane A2; Thromboxane B2; Thromboxanes	1985
Effect of prostaglandin blockers on ascites fluid in pancreatitis. Surgery, 1985, Volume: 98, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Ascitic Fluid; Biological Assay; Electrolytes; Epoprostenol; Female; Hemorrhage; Hydrogen-Ion Concentration; Ibuprofen; Methylprednisolone; Mice; Osmolar Concentration; Pancreatitis; Swine; Thromboxane B2	1985
Prostaglandin involvement in hypersensitivity of ischemic hearts to arrhythmogenic influence of ouabain. The American journal of physiology, 1985, Volume: 249, Issue:1 Pt 2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Arrhythmias, Cardiac; Aspirin; Coronary Circulation; Coronary Disease; Coronary Vessels; Dinoprost; Dinoprostone; Epoprostenol; Guinea Pigs; Ibuprofen; Indomethacin; Ligation; Male; Ouabain; Perfusion; Prostaglandins; Prostaglandins E; Prostaglandins F; Time Factors	1985
The effects of diclofenac sodium on arachidonic acid metabolism. Seminars in arthritis and rheumatism, 1985, Volume: 15, Issue:2 Suppl 1 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Chemotaxis, Leukocyte; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indomethacin; Leukocytes; Lipoxygenase; Naproxen; Phospholipases A; Phospholipases A2; Phospholipids; Piroxicam; Prostaglandins E; SRS-A; Thiazines; Triglycerides	1985
Mechanical trauma to bladder epithelium liberates prostanoids which modulate neurotransmission in rabbit detrusor muscle. The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bethanechol; Bethanechol Compounds; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Epithelium; Fatty Acids; Ibuprofen; Indomethacin; Male; Muscle Contraction; Neuromuscular Junction; Prostaglandins E; Prostanoic Acids; Rabbits; Synaptic Transmission; Urinary Bladder	1984
Regional blood flow and pulmonary thromboxane release after sublethal endotoxin infusion in sheep. Surgery, 1984, Volume: 95, Issue:4 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Endotoxins; Escherichia coli; Hemodynamics; Ibuprofen; Lung; Prostaglandins F; Regional Blood Flow; Sheep; Thromboxane A2; Thromboxane B2; Thromboxanes	1984
Inhibition of prostaglandin synthesis restores normal hemodynamics in canine hyperdynamic sepsis. Annals of surgery, 1984, Volume: 200, Issue:5 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Disease Models, Animal; Dogs; Escherichia coli Infections; Female; Hemodynamics; Ibuprofen; Indomethacin; Male; Oxygen Consumption; Peritonitis; Prostaglandin Antagonists; Prostaglandins; Sepsis; Shock, Septic; Thromboxane A2	1984
Effects of cyclooxygenase inhibitors on the alterations in lung mechanics caused by endotoxemia in the unanesthetized sheep. The Journal of clinical investigation, 1983, Volume: 72, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Airway Resistance; Animals; Cyclooxygenase Inhibitors; Endotoxins; Escherichia coli; Hemodynamics; Ibuprofen; Lung; Lung Compliance; Lymph; Meclofenamic Acid; Pulmonary Gas Exchange; Thromboxane B2	1983
Promotion of vascular patency in dermal burns with ibuprofen. The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Vessels; Body Fluids; Burns; Fibrinolysis; Freezing; Ibuprofen; Imidazoles; Indomethacin; Prostaglandin Antagonists; Rats; Rats, Inbred Strains; Skin; Thromboxane B2; Time Factors; Wound Healing	1984
Modification of inflammatory response to aspiration with ibuprofen. The American journal of physiology, 1982, Volume: 243, Issue:6 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Platelets; Blood Pressure; Dogs; Epoprostenol; Ibuprofen; Inhalation; Kinetics; Leukocyte Count; Lung; Pulmonary Edema; Respiration; Thrombocytosis; Thromboxane B2	1982
Implications for thromboxane A2 in the pathogenesis of endotoxic shock. Advances in shock research, 1981, Volume: 6 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprost; Disseminated Intravascular Coagulation; Fibrin Fibrinogen Degradation Products; Ibuprofen; Indomethacin; Male; Muridae; Prostaglandins E; Prostaglandins F; Shock, Septic; Thromboxane A2; Thromboxanes	1981
Comparative effect of ibuprofen on endothelial and platelet prostaglandin synthesis. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 219, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Blood Platelets; Blood Vessels; Endothelium; Epoprostenol; Humans; Ibuprofen; In Vitro Techniques; Platelet Adhesiveness; Prostaglandins; Thromboxane A2; Thromboxane B2	1981
Adverse effects of prostacyclin used to perfuse isolated lung lobes. The American journal of physiology, 1982, Volume: 242, Issue:5 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Biomechanical Phenomena; Dogs; Epoprostenol; Ibuprofen; Lung; Perfusion; Platelet Count; Prostaglandins; Thromboxane B2	1982
Comparison of the anti-inflammatory activity and gastrointestinal irritancy of nabumetone, ibuprofen, and diclofenac in rats following chronic administration. European journal of rheumatology and inflammation, 1994, Volume: 14, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Butanones; Carrageenan; Cecum; Diclofenac; Digestive System; Drug Administration Schedule; Gastric Mucosa; Gastrointestinal Diseases; Haptoglobins; Hemoglobins; Ibuprofen; Ileum; Male; Nabumetone; Rats; Rats, Wistar	1994
The mechanism of coronary collateral vasoconstriction in response to cyclooxygenase blockade. Circulation research, 1994, Volume: 74, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Collateral Circulation; Coronary Circulation; Cyclooxygenase Inhibitors; Dogs; Epoprostenol; Ibuprofen; Lipoxygenase Inhibitors; Thromboxanes; Vasoconstriction	1994
Effect of ibuprofen on regional eicosanoid production and neuronal injury after forebrain ischemia in rats. Brain research, 1993, Jun-18, Volume: 614, Issue:1-2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Body Weight; Brain Ischemia; Caudate Nucleus; Cell Death; Dialysis; Dinoprost; Eicosanoids; Hippocampus; Ibuprofen; Neurons; Prosencephalon; Rats; Rats, Inbred WKY; Stereotaxic Techniques	1993
Tumor necrosis factor-induced mortality is reversed with cyclooxygenase inhibition. Annals of surgery, 1993, Volume: 217, Issue:6 Topics: 6-Ketoprostaglandin F1 alpha; Acidosis; Animals; Antibodies, Monoclonal; Bicarbonates; Blood Pressure; Carbon Dioxide; Cause of Death; Dinoprostone; Dose-Response Relationship, Drug; Eicosanoids; Epoprostenol; Ibuprofen; Male; Oxygen; Rats; Rats, Sprague-Dawley; Thromboxane B2; Tumor Necrosis Factor-alpha	1993
Cerebral arteriolar dilation to hypoxia: role of prostanoids. The American journal of physiology, 1997, Volume: 272, Issue:1 Pt 2 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Animals, Newborn; Arterioles; Cerebrovascular Circulation; Hypercapnia; Hypoxia; Ibuprofen; Indomethacin; Pia Mater; Prostaglandins; Swine; Vasoconstriction; Vasodilation	1997
Amelioration of polyuria in nephrogenic diabetes insipidus due to aquaporin-2 deficiency. Clinical endocrinology, 1998, Volume: 49, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aquaporin 2; Aquaporin 6; Aquaporins; Child; Child, Preschool; Combined Modality Therapy; Deamino Arginine Vasopressin; Diabetes Insipidus, Nephrogenic; Diet, Sodium-Restricted; Dinoprostone; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Ibuprofen; Infant; Male; Osmolar Concentration; Polyuria; Vasopressins	1998
Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. Proceedings of the National Academy of Sciences of the United States of America, 1999, Jan-05, Volume: 96, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Adult; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Epoprostenol; Female; Humans; Ibuprofen; Isoenzymes; Male; Membrane Proteins; Middle Aged; Monocytes; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Thromboxane B2	1999
In vitro prostanoid release from spinal cord following peripheral inflammation: effects of substance P, NMDA and capsaicin. British journal of pharmacology, 1999, Volume: 126, Issue:6 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capsaicin; Carrageenan; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Ibuprofen; In Vitro Techniques; Inflammation; Knee Joint; Male; N-Methylaspartate; Prostaglandins; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance P; Thromboxane B2	1999
The role of prostanoids and nitric oxide in endotoxin-induced hyporesponsiveness of equine digital blood vessels. Equine veterinary journal, 1999, Volume: 31, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Culture Techniques; Cycloheximide; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Foot Diseases; Free Radical Scavengers; Hoof and Claw; Horse Diseases; Horses; Ibuprofen; Inflammation; Leukocytes; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Prostaglandins; Protein Synthesis Inhibitors; Serotonin; Vasoconstriction; Veins	1999
Cyclooxygenase-independent inhibition of smooth muscle cell mitogenesis by ibuprofen. European journal of pharmacology, 2000, Feb-11, Volume: 389, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Becaplermin; Cattle; Cell Division; Cells, Cultured; Cyclooxygenase Inhibitors; DNA; Dose-Response Relationship, Drug; Ibuprofen; Indomethacin; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Stereoisomerism	2000
Effect of Ibuprofen on interleukin-1beta-induced abnormalities in hemodynamics and oxygen metabolism in rabbits. Shock (Augusta, Ga.), 2003, Volume: 20, Issue:6 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Gas Analysis; Cardiac Output; Cardiac Tamponade; Cytokines; Epoprostenol; Hemodynamics; Humans; Hypoxia; Ibuprofen; Interleukin-1; Oxygen; Oxygen Consumption; Pressure; Rabbits; Shock; Time Factors	2003
Early postnatal ibuprofen and indomethacin effects in suckling and weanling rat kidneys. Prostaglandins & other lipid mediators, 2008, Volume: 85, Issue:3-4 Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Animals, Newborn; Animals, Suckling; Cyclooxygenase 2; Dinoprost; Dinoprostone; Ductus Arteriosus, Patent; Ibuprofen; Indomethacin; Kidney; Prostaglandins; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Thromboxane B2	2008
Differences in the in vitro antiplatelet effect of dexibuprofen, ibuprofen, and flurbiprofen in human blood. Anesthesia and analgesia, 2010, Volume: 111, Issue:6 Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Platelets; Dinoprostone; Dose-Response Relationship, Drug; Female; Flurbiprofen; Humans; Ibuprofen; Leukocytes; Male; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2	2010