ibuprofen acyl glucuronide has been researched along with ibuprofen in 8 studies
| Studies (ibuprofen acyl glucuronide) | Trials (ibuprofen acyl glucuronide) | Recent Studies (post-2010) (ibuprofen acyl glucuronide) | Studies (ibuprofen) | Trials (ibuprofen) | Recent Studies (post-2010) (ibuprofen) |
|---|---|---|---|---|---|
| 9 | 0 | 5 | 10,245 | 1,781 | 4,267 |
| Protein | Taxonomy | ibuprofen acyl glucuronide (IC50) | ibuprofen (IC50) |
|---|---|---|---|
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | 2.9 | |
| Prostaglandin G/H synthase 2 | Bos taurus (cattle) | 1.1 | |
| Albumin | Bos taurus (cattle) | 3 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 4.0919 | |
| Prostaglandin G/H synthase 1 | Mus musculus (house mouse) | 0.22 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 1.6273 | |
| Caspase-1 | Homo sapiens (human) | 7.2667 | |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | 1.1 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 3.0687 | |
| Prostaglandin G/H synthase 2 | Rattus norvegicus (Norway rat) | 1.3 | |
| Aldo-keto reductase family 1 member C3 | Homo sapiens (human) | 10 | |
| Caspase-3 | Homo sapiens (human) | 7.2667 | |
| Caspase-4 | Homo sapiens (human) | 7.2667 | |
| 4-aminobutyrate aminotransferase, mitochondrial | Rattus norvegicus (Norway rat) | 1.1 | |
| Caspase-5 | Homo sapiens (human) | 7.2667 | |
| Caspase-9 | Homo sapiens (human) | 7.2667 | |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | 1.1375 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 2.9 | |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | 5 | |
| Prostaglandin G/H synthase 2 | Mus musculus (house mouse) | 0.54 | |
| Solute carrier family 22 member 6 | Homo sapiens (human) | 8 | |
| Prostaglandin G/H synthase 1 | Rattus norvegicus (Norway rat) | 1.3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T | 1 |
| Castillo, M; Smith, PC | 2 |
| Castillo, M; Dooley, MA; Lam, YW; Smith, PC; Stahl, E | 1 |
| Lindon, JC; Nicholson, JK; Troke, J; Vanderhoeven, SJ; Wilson, ID | 1 |
| Boyle, B; Bristow, AW; Creaser, CS; Ray, A; Reynolds, JC; Sage, A; Smith, RW; Toutoungi, DE; Weston, DJ; Wilson, ID | 1 |
| Fujiwara, R; Hashimoto, M; Itoh, T; Narawa, T; Takenaka, S | 1 |
| De Logu, F; De Siena, G; Geppetti, P; Landini, L; Li Puma, S; Nassini, R; Patacchini, R; Poli, G; Preti, D; Tsagareli, MG; Tuccinardi, T | 1 |
8 other study(ies) available for ibuprofen acyl glucuronide and ibuprofen
| Article | Year |
|---|---|
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney | 2011 |
Disposition and reactivity of ibuprofen and ibufenac acyl glucuronides in vivo in the rhesus monkey and in vitro with human serum albumin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Buffers; Chromatography, High Pressure Liquid; Drug Stability; Female; Glucuronates; Humans; Hydrogen-Ion Concentration; Ibuprofen; Macaca mulatta; Male; Phenylacetates; Protein Binding; Serum Albumin | 1995 |
Disposition and covalent binding of ibuprofen and its acyl glucuronide in the elderly.
Topics: Administration, Oral; Aged; Aging; Glucuronates; Humans; Ibuprofen | 1995 |
Direct determination of ibuprofen and ibuprofen acyl glucuronide in plasma by high-performance liquid chromatography using solid-phase extraction.
Topics: Chromatography, High Pressure Liquid; Glucuronates; Humans; Ibuprofen; Reproducibility of Results; Spectrophotometry, Ultraviolet | 1993 |
NMR spectroscopic studies of the transacylation reactivity of ibuprofen 1-beta-O-acyl glucuronide.
Topics: Acylation; Glucuronates; Hydrolysis; Ibuprofen; Magnetic Resonance Spectroscopy | 2006 |
Enhanced performance in the determination of ibuprofen 1-β-O-acyl glucuronide in urine by combining high field asymmetric waveform ion mobility spectrometry with liquid chromatography-time-of-flight mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Glucuronates; Humans; Ibuprofen; Mass Spectrometry | 2013 |
Expression of human solute carrier family transporters in skin: possible contributor to drug-induced skin disorders.
Topics: Biological Transport; Carrier Proteins; Cell Line; Cell Survival; Glucuronates; Humans; Ibuprofen; Intestine, Small; Keratinocytes; Liver; Membrane Transport Proteins; S100 Calcium Binding Protein A7; S100 Proteins; Skin; Skin Diseases | 2014 |
The acyl-glucuronide metabolite of ibuprofen has analgesic and anti-inflammatory effects via the TRPA1 channel.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Cell Line; Dinoprostone; Epithelial Cells; Glucuronates; Humans; Hyperalgesia; Ibuprofen; Interleukin-8; Male; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pain; Rats, Sprague-Dawley; TRPA1 Cation Channel | 2019 |