Compounds > ibuprofen, (r)-isomer
Page last updated: 2024-09-02

ibuprofen, (r)-isomer and indomethacin

ibuprofen, (r)-isomer has been researched along with indomethacin in 4 studies

Compound Research Comparison

Studies
(ibuprofen, (r)-isomer)		Trials
(ibuprofen, (r)-isomer)		Recent Studies (post-2010)
(ibuprofen, (r)-isomer)		Studies
(indomethacin)		Trials
(indomethacin)		Recent Studies (post-2010) (indomethacin)
100429,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomyibuprofen, (r)-isomer (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Allegretti, M; Aramini, A; Aschi, M; Bertini, R; Bizzarri, C; Cesta, MC; Crucianelli, M; Di Bitondo, R; Di Giacinto, C; Gloaguen, I; Moriconi, A; Sablone, MR1
Björklund, E; Congiu, C; Fowler, CJ; Hempel, F; Onnis, V; Söderström, E1
Bellman, K; Knegtel, RM; Settimo, L1

Reviews

1 review(s) available for ibuprofen, (r)-isomer and indomethacin

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

3 other study(ies) available for ibuprofen, (r)-isomer and indomethacin

ArticleYear
Structure-Activity Relationship of novel phenylacetic CXCR1 inhibitors.
    Bioorganic & medicinal chemistry letters, 2009, Aug-01, Volume: 19, Issue:15

    Topics: Allosteric Regulation; Allosteric Site; Chemistry, Organic; Chemistry, Pharmaceutical; Chemotaxis; Humans; Inhibitory Concentration 50; Models, Chemical; Models, Molecular; Molecular Conformation; Mutagenesis; Mutation; Receptors, Interleukin-8A; Structure-Activity Relationship

2009
Synthesis and evaluation of paracetamol esters as novel fatty acid amide hydrolase inhibitors.
    Journal of medicinal chemistry, 2010, Mar-11, Volume: 53, Issue:5

    Topics: Amidohydrolases; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Benzoates; Cell Line, Tumor; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Inhibitors; Inhibitory Concentration 50; Kinetics; Magnetic Resonance Spectroscopy; Polyunsaturated Alkamides; Pyridines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Spectrophotometry, Infrared; Structure-Activity Relationship

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014