Page last updated: 2024-09-05

ibogaine and varenicline

ibogaine has been researched along with varenicline in 2 studies

Compound Research Comparison

Studies (ibogaine)	Trials (ibogaine)	Recent Studies (post-2010) (ibogaine)	Studies (varenicline)	Trials (varenicline)	Recent Studies (post-2010) (varenicline)
445	8	136	1,597	381	1,154

Protein Interaction Comparison

Protein	Taxonomy	varenicline (IC50)
Neuronal acetylcholine receptor subunit alpha-4	Rattus norvegicus (Norway rat)	0.2
Neuronal acetylcholine receptor subunit beta-2	Rattus norvegicus (Norway rat)	0.2
Neuronal acetylcholine receptor subunit beta-2	Homo sapiens (human)	0.0672
Neuronal acetylcholine receptor subunit beta-4	Homo sapiens (human)	0.11
Neuronal acetylcholine receptor subunit alpha-3	Homo sapiens (human)	0.11
Neuronal acetylcholine receptor subunit alpha-4	Homo sapiens (human)	0.0672

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chang, Q; Hanania, T; Maillet, EL; Mash, DC	1
de Moura, FB; McMahon, LR	1

Other Studies

2 other study(ies) available for ibogaine and varenicline

Article	Year
Noribogaine reduces nicotine self-administration in rats. Journal of psychopharmacology (Oxford, England), 2015, Volume: 29, Issue:6 Topics: Animals; Dose-Response Relationship, Drug; Ibogaine; Male; Nicotine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Self Administration; Smoking Cessation; Tobacco Use Disorder; Varenicline	2015
The contribution of α4β2 and non-α4β2 nicotinic acetylcholine receptors to the discriminative stimulus effects of nicotine and varenicline in mice. Psychopharmacology, 2017, Volume: 234, Issue:5 Topics: Aconitine; Alkaloids; alpha7 Nicotinic Acetylcholine Receptor; Animals; Azocines; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Dihydro-beta-Erythroidine; Discrimination, Psychological; Dopamine Uptake Inhibitors; Hypnotics and Sedatives; Ibogaine; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Midazolam; Nerve Tissue Proteins; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Quinolizines; Receptors, Nicotinic; Varenicline	2017

Article

Year

Noribogaine reduces nicotine self-administration in rats.

Journal of psychopharmacology (Oxford, England), 2015, Volume: 29, Issue:6

Topics: Animals; Dose-Response Relationship, Drug; Ibogaine; Male; Nicotine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Self Administration; Smoking Cessation; Tobacco Use Disorder; Varenicline

2015

The contribution of α4β2 and non-α4β2 nicotinic acetylcholine receptors to the discriminative stimulus effects of nicotine and varenicline in mice.

Psychopharmacology, 2017, Volume: 234, Issue:5

Topics: Aconitine; Alkaloids; alpha7 Nicotinic Acetylcholine Receptor; Animals; Azocines; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Dihydro-beta-Erythroidine; Discrimination, Psychological; Dopamine Uptake Inhibitors; Hypnotics and Sedatives; Ibogaine; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Midazolam; Nerve Tissue Proteins; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Quinolizines; Receptors, Nicotinic; Varenicline

2017