ibogaine has been researched along with u-50488 in 4 studies
| Studies (ibogaine) | Trials (ibogaine) | Recent Studies (post-2010) (ibogaine) | Studies (u-50488) | Trials (u-50488) | Recent Studies (post-2010) (u-50488) |
|---|---|---|---|---|---|
| 445 | 8 | 136 | 1,664 | 3 | 209 |
| Protein | Taxonomy | ibogaine (IC50) | u-50488 (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 2.15 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.0027 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 2.15 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.7171 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0958 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.0537 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bhargava, HN; Cao, YJ; Zhao, GM | 1 |
| Bhargava, HN; Cao, YJ | 1 |
| Mash, DC; Pablo, J; Shoaib, M; Stolerman, IP; Zubaran, C | 1 |
| Arena, E; Aricò, G; Bertucci, C; Campisi, A; Parenti, C; Pistolozzi, M; Prezzavento, O; Ronsisvalle, G; Ronsisvalle, S; Scoto, GM; Vanella, A | 1 |
4 other study(ies) available for ibogaine and u-50488
| Article | Year |
|---|---|
Effects of ibogaine and noribogaine on the antinociceptive action of mu-, delta- and kappa-opioid receptor agonists in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ibogaine; Male; Mice; Morphine; Narcotics; Nociceptors; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1997 |
Effects of ibogaine on the development of tolerance to antinociceptive action of mu-, delta- and kappa-opioid receptor agonists in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ibogaine; Male; Mice; Morphine; Narcotics; Nociceptors; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 1997 |
Noribogaine generalization to the ibogaine stimulus: correlation with noribogaine concentration in rat brain.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Animals; Brain; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Generalization, Psychological; Hallucinogens; Ibogaine; Male; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa | 1999 |
Synthesis and resolution of cis-(+/-)-methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperidin-1-yl)methyl]-1-(4-methylphenyl)cyclopropanecarboxylate [(+/-)-PPCC)]: new sigma receptor ligands with neuroprotective effect.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Animals; Astrocytes; Cells, Cultured; Cyclopropanes; Drug Interactions; Glutamic Acid; Glutathione; GTP-Binding Proteins; Ibogaine; Ligands; Neuroprotective Agents; Oxidative Stress; Pentazocine; Piperidines; Protein Glutamine gamma Glutamyltransferase 2; Rats; Reactive Oxygen Species; Receptors, Opioid, kappa; Receptors, sigma; Stereoisomerism; Structure-Activity Relationship; Transglutaminases | 2010 |