Page last updated: 2024-09-05

ibogaine and noribogaine

ibogaine has been researched along with noribogaine in 51 studies

Compound Research Comparison

Studies (ibogaine)	Trials (ibogaine)	Recent Studies (post-2010) (ibogaine)	Studies (noribogaine)	Trials (noribogaine)	Recent Studies (post-2010) (noribogaine)
445	8	136	52	6	21

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	19 (37.25)	18.2507
2000's	10 (19.61)	29.6817
2010's	18 (35.29)	24.3611
2020's	4 (7.84)	2.80

Authors

Authors	Studies
Glick, SD; Herrick-Davis, K; Pearl, SM; Teitler, M	1
Cai, J; Glick, SD; Maisonneuve, IM; Pearl, SM	1
Flynn, DD; Hearn, WL; Mash, DC; Ouyang, Q; Pablo, J; Rice, KC; Rothman, RB; Staley, JK	1
Rabin, RA; Winter, JC	2
Alburges, ME; Foltz, RL; Moody, DE	1
Hearn, WL; Hime, GW; Mash, DC; Pablo, J	1
Bagal, AA; Glick, SD; Hough, LB; Nalwalk, JW	1
Helsley, S; Rabin, RA; Winter, JC	1
Bhargava, HN; Cao, YJ; Zhao, GM	1
Boyd, DL; Glick, SD; Hough, LB; Pearl, SM	1
Bandarage, UK; Glick, SD; Kuehne, ME; Maisonneuve, IM; Mann, GL; Visker, KE	1
Bhargava, HN; Cao, YJ	1
Mash, DC; Pablo, JP	1
Glick, SD; Maisonneuve, IS	1
Glick, SD; Kuehne, ME; Maisonneuve, IM; Wei, D	1
Mash, DC; Obach, RS; Pablo, J	1
Bhargava, HN; Sunder Sharma, S	1
Mash, DC; Pablo, J; Shoaib, M; Stolerman, IP; Zubaran, C	1
Ali, SF; Baumann, MH; Mash, DC; Pablo, JP; Rothman, RB	1
Ervin, FD; Kovera, CA; Mash, DC; Mayor, M; Pablo, J; Singleton, EG; Tyndale, RF; Williams, IC	1
Baumann, MH; Mash, DC; Pablo, JP; Rothman, RB	1
Ali, SF; Baumann, MH; Mash, DC; Pablo, J; Rothman, RB	1
Vastag, B	1
Bressolle, F; Briedis, V; Kontrimaviciūte, V; Larroque, M; Margout, D	1
Bressolle, FM; Breton, H; Kontrimaviciūte, V; Mathieu, O; Mathieu-Daudé, JC	1
Baccino, E; Bressolle, FM; Casper, T; Kontrimaviciūte, V; Mathieu, O; Mathieu-Daudé, JC; Vainauskas, P	1
Chèze, M; Deveaux, M; Lenoan, A; Pépin, G	1
Ivanov, L; Kazlauskas, S; Kubiliene, A; Marksiene, R; Razukas, A; Sadauskiene, I	1
Carnicella, S; Glick, SD; He, DY; Ron, D; Yowell, QV	1
Alper, K; Antonio, T; Bornmann, WG; Childers, SR; Dersch, CM; Eshleman, AJ; Janowsky, A; King, C; Kuehne, M; Reith, ME; Rothman, RB; Simon, ER	1
El-Kasaby, A; Freissmuth, M; Koban, F; Sitte, HH; Sucic, S	1
Friedhoff, L; Glue, P; Hung, CT; Hung, N; Lam, F; Lockhart, M	1
Alper, K; Bai, R; Fowler, SJ; Huang, XP; Liu, N; Priori, SG; Ruan, Y	1
Garbe, K; Glue, P; Hung, CT; Jakobi, H; Lenagh-Glue, Z; Lyudin, A; Winter, H	1
Chang, Q; Hanania, T; Maillet, EL; Mash, DC	1
Fishback, J; Garamszegi, N; Heghinian, MD; Maillet, EL; Mash, DC; Milon, N; Schürer, SC	1
Cape, G; Devane, J; Friedhoff, L; Glue, P; Gray, A; Harland, S; Howes, J; Hung, CT; Hung, N; Lam, F; Lockhart, M; Tunnicliff, D; Weis, H	1
Boehm, S; Eckert, D; Hilber, K; Koenig, X; Rubi, L	1
Ameer, B; Howes, JF; Maillet, EL; Mash, DC; Prou, D	1
Forsyth, B; Garbe, K; Glue, P; Jakobi, H; Jowett, T; Machado, L; Winter, H	1
Asjad, HMM; El-Kasaby, A; Freissmuth, M; Grimm, A; Hummel, T; Kasture, A; Stockner, T; Sucic, S; Szöllősi, D	1
Kuszczak, B; Olszak, N; Zdrojewicz, Z	1
Cape, G; Crockett, RS; Darpo, B; Devane, J; Friedhoff, L; Glue, P; Harland, S; Howes, J; Hung, CT; Hung, N; Lam, F; Lockhart, M; Tunnicliff, D; Weis, H; Zhou, M	1
Kalueff, AV; Kaluyeva, A; Maillet, EL	1
Deng, JF; Yip, L	1
Asjad, HMM; El-Kasaby, A; Freissmuth, M; Hummel, T; Kasture, A; Sackel, M; Sucic, S	1
Anouar, Y; Arias, HR; Chagraoui, A; Chen, Z; Do Rego, JC; Do Rego, JL; Gonzales, EB; Huang, R; Scholze, P	1
Carrera, I; Fabius, S; Havel, V; Prieto, JP; Reyes, AL; Rodrı Guez, P; Sames, D; Scorza, C; Urbanavicius, J	1
Aćimović, T; Atanasijević, T; Bogdanović, M; Denić, K; Lukić, V; Popović, V	1
Canessa, C; Chiappini, S; Corkery, JM; Di Carlo, F; Di Giannantonio, M; Mancusi, G; Martinotti, G; Miuli, A; Mosca, A; Pettorruso, M; Santovito, MC	1

Reviews

4 review(s) available for ibogaine and noribogaine

Article	Year
Mechanisms of antiaddictive actions of ibogaine. Annals of the New York Academy of Sciences, 1998, May-30, Volume: 844 Topics: Animals; Cocaine; Female; Ibogaine; Morphine; Rats; Rats, Sprague-Dawley; Self Administration; Substance-Related Disorders; Tobacco Use Disorder	1998
Comparative neuropharmacology of ibogaine and its O-desmethyl metabolite, noribogaine. The Alkaloids. Chemistry and biology, 2001, Volume: 56 Topics: Animals; Behavior, Animal; Brain; Corticosterone; Dopamine; Humans; Ibogaine; Opioid-Related Disorders; Serotonin	2001
[Ibogaine - structure, influence on human body, clinical relevance]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2016, Jul-29, Volume: 41, Issue:241 Topics: Cardiotoxicity; Humans; Ibogaine; Neurotoxicity Syndromes; Substance-Related Disorders	2016
Ibogaine/Noribogaine in the Treatment of Substance Use Disorders: A Systematic Review of the Current Literature. Current neuropharmacology, 2023, Volume: 21, Issue:11 Topics: Humans; Ibogaine; Substance-Related Disorders	2023

Trials

6 trial(s) available for ibogaine and noribogaine

Article	Year
Ibogaine: complex pharmacokinetics, concerns for safety, and preliminary efficacy measures. Annals of the New York Academy of Sciences, 2000, Volume: 914 Topics: Adult; Cocaine; Depression; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Humans; Ibogaine; Male; Narcotics; Substance-Related Disorders; Surveys and Questionnaires; Time Factors	2000
Ascending-dose study of noribogaine in healthy volunteers: pharmacokinetics, pharmacodynamics, safety, and tolerability. Journal of clinical pharmacology, 2015, Volume: 55, Issue:2 Topics: Adult; Double-Blind Method; Glucuronides; Healthy Volunteers; Humans; Ibogaine; Male; Young Adult	2015
Influence of CYP2D6 activity on the pharmacokinetics and pharmacodynamics of a single 20 mg dose of ibogaine in healthy volunteers. Journal of clinical pharmacology, 2015, Volume: 55, Issue:6 Topics: Adult; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Half-Life; Healthy Volunteers; Humans; Ibogaine; Male; Paroxetine; Time Factors; Young Adult	2015
Switching Opioid-Dependent Patients From Methadone to Morphine: Safety, Tolerability, and Methadone Pharmacokinetics. Journal of clinical pharmacology, 2016, Volume: 56, Issue:8 Topics: Adult; Analgesics, Opioid; Double-Blind Method; Drug Substitution; Female; Headache; Humans; Ibogaine; Male; Methadone; Morphine; Nausea; Opiate Substitution Treatment; Opioid-Related Disorders; Treatment Outcome	2016
Effects of low dose ibogaine on subjective mood state and psychological performance. Journal of ethnopharmacology, 2016, Aug-02, Volume: 189 Topics: Adult; Affect; Attention; Central Nervous System Agents; Cognition; Double-Blind Method; Drug Administration Schedule; Healthy Volunteers; Humans; Ibogaine; Male; Neuropsychological Tests; New Zealand; Phytotherapy; Plants, Medicinal; Psychometrics; Young Adult	2016
Ascending Single-Dose, Double-Blind, Placebo-Controlled Safety Study of Noribogaine in Opioid-Dependent Patients. Clinical pharmacology in drug development, 2016, Volume: 5, Issue:6 Topics: Adult; Area Under Curve; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Female; Heart Rate; Humans; Ibogaine; Long QT Syndrome; Male; Methadone; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Substance Withdrawal Syndrome	2016

Other Studies

41 other study(ies) available for ibogaine and noribogaine

Article	Year
Radioligand-binding study of noribogaine, a likely metabolite of ibogaine. Brain research, 1995, Mar-27, Volume: 675, Issue:1-2 Topics: Analgesics; Animals; Benzeneacetamides; Cattle; Cerebral Cortex; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ibogaine; In Vitro Techniques; Kinetics; Naloxone; Pyrrolidines; Radioligand Assay; Receptors, Opioid	1995
Ibogaine-like effects of noribogaine in rats. Brain research, 1996, Mar-25, Volume: 713, Issue:1-2 Topics: Animals; Female; Ibogaine; Locomotion; Medicine, African Traditional; Morphine; Rats; Rats, Sprague-Dawley; Self Administration; Substance-Related Disorders; Time Factors	1996
Pharmacological screen for activities of 12-hydroxyibogamine: a primary metabolite of the indole alkaloid ibogaine. Psychopharmacology, 1996, Volume: 127, Issue:1 Topics: Binding Sites; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Corpus Striatum; Dopamine; Gas Chromatography-Mass Spectrometry; Humans; Ibogaine; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Serotonin	1996
Effects of ibogaine and noribogaine on phosphoinositide hydrolysis. Brain research, 1996, Aug-26, Volume: 731, Issue:1-2 Topics: Animals; Female; Hallucinogens; Hydrolysis; Ibogaine; Neostriatum; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Signal Transduction; Tritium	1996
Determination of ibogaine and 12-hydroxy-ibogamine in plasma by gas chromatography-positive ion chemical ionization-mass spectrometry. Journal of analytical toxicology, 1995, Volume: 19, Issue:6 Topics: Acetamides; Acetonitriles; Butanes; Calibration; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Hydroxylation; Ibogaine; Organosilicon Compounds; Quality Control; Reference Standards; Temperature; Trifluoroacetic Acid	1995
Identification and quantitation of ibogaine and an o-demethylated metabolite in brain and biological fluids using gas chromatography-mass spectrometry. Journal of analytical toxicology, 1995, Volume: 19, Issue:6 Topics: Administration, Oral; Animals; Brain; Calibration; Chlorocebus aethiops; Dimethyl Sulfoxide; Gas Chromatography-Mass Spectrometry; Humans; Hydrogen-Ion Concentration; Ibogaine; Macaca fascicularis; Methylation; Netherlands; Reference Standards; Reproducibility of Results	1995
Ibogaine and noribogaine potentiate the inhibition of adenylyl cyclase activity by opioid and 5-HT receptors. European journal of pharmacology, 1996, Dec-05, Volume: 316, Issue:2-3 Topics: Adenylyl Cyclases; Animals; Dose-Response Relationship, Drug; Hippocampus; Ibogaine; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Serotonin	1996
Modulation of morphine-induced antinociception by ibogaine and noribogaine. Brain research, 1996, Nov-25, Volume: 741, Issue:1-2 Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Interactions; Ibogaine; Male; Morphine; Pain Measurement; Psychotropic Drugs; Rats; Rats, Sprague-Dawley; Time Factors	1996
The effects of noribogaine and harmaline in rats trained with ibogaine as a discriminative stimulus. Life sciences, 1997, Volume: 60, Issue:9 Topics: Animals; Discrimination Learning; Hallucinogens; Harmaline; Humans; Ibogaine; Male; Rats; Rats, Inbred F344; Substance-Related Disorders; Time Factors	1997
Effects of ibogaine and noribogaine on the antinociceptive action of mu-, delta- and kappa-opioid receptor agonists in mice. Brain research, 1997, Mar-28, Volume: 752, Issue:1-2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Ibogaine; Male; Mice; Morphine; Narcotics; Nociceptors; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	1997
Sex differences in ibogaine antagonism of morphine-induced locomotor activity and in ibogaine brain levels and metabolism. Pharmacology, biochemistry, and behavior, 1997, Volume: 57, Issue:4 Topics: Animals; Brain; Drug Antagonism; Female; Hallucinogens; Ibogaine; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Morphine; Motor Activity; Narcotics; Rats; Rats, Sprague-Dawley; Sex Factors; Time Factors	1997
Time-dependent interactions between iboga agents and cocaine. European journal of pharmacology, 1997, Oct-08, Volume: 336, Issue:2-3 Topics: Animals; Cocaine; Drug Interactions; Female; Ibogaine; Motor Activity; Narcotics; Rats; Rats, Sprague-Dawley; Time Factors	1997
Effects of noribogaine on the development of tolerance to antinociceptive action of morphine in mice. Brain research, 1997, Oct-17, Volume: 771, Issue:2 Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Ibogaine; Injections, Intraperitoneal; Male; Mice; Morphine; Pain Measurement; Receptors, Opioid	1997
Noribogaine stimulates naloxone-sensitive [35S]GTPgammaS binding. Neuroreport, 1998, Jan-05, Volume: 9, Issue:1 Topics: Animals; Binding, Competitive; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guanosine 5'-O-(3-Thiotriphosphate); Ibogaine; Logistic Models; Male; Naloxone; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Stimulation, Chemical; Sulfur Radioisotopes	1998
Acute iboga alkaloid effects on extracellular serotonin (5-HT) levels in nucleus accumbens and striatum in rats. Brain research, 1998, Aug-03, Volume: 800, Issue:2 Topics: Animals; Corpus Striatum; Extracellular Space; Female; Hallucinogens; Ibogaine; Injections, Intraperitoneal; Injections, Intravenous; Microdialysis; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Serotonin; Synaptic Transmission	1998
Cytochrome P4502D6 catalyzes the O-demethylation of the psychoactive alkaloid ibogaine to 12-hydroxyibogamine. Drug metabolism and disposition: the biological fate of chemicals, 1998, Volume: 26, Issue:8 Topics: Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Enzyme Inhibitors; Hallucinogens; Humans; Ibogaine; Isoenzymes; Kinetics; Methylation; Microsomes, Liver	1998
Enhancement of morphine antinociception by ibogaine and noribogaine in morphine-tolerant mice. Pharmacology, 1998, Volume: 57, Issue:5 Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Implants; Drug Synergism; Drug Tolerance; Hallucinogens; Ibogaine; Injections, Intraperitoneal; Male; Mice; Morphine; Pain	1998
Noribogaine generalization to the ibogaine stimulus: correlation with noribogaine concentration in rat brain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 21, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Animals; Brain; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Generalization, Psychological; Hallucinogens; Ibogaine; Male; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa	1999
Noribogaine (12-hydroxyibogamine): a biologically active metabolite of the antiaddictive drug ibogaine. Annals of the New York Academy of Sciences, 2000, Volume: 914 Topics: Analysis of Variance; Animals; Behavior, Animal; Binding Sites; Dialysis; Dopamine; Dose-Response Relationship, Drug; Drug Administration Routes; Excitatory Amino Acid Antagonists; Ibogaine; Male; Neurosecretory Systems; Rats; Rats, Sprague-Dawley; Serotonin	2000
In vivo neurobiological effects of ibogaine and its O-desmethyl metabolite, 12-hydroxyibogamine (noribogaine), in rats. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:2 Topics: Animals; Behavior, Animal; Brain Chemistry; Carrier Proteins; Dopamine Plasma Membrane Transport Proteins; Ibogaine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Nerve Tissue Proteins; Neurotoxins; Rats; Rats, Sprague-Dawley; Serotonin Plasma Membrane Transport Proteins	2001
Addiction research. Ibogaine therapy: a 'vast, uncontrolled experiment'. Science (New York, N.Y.), 2005, Apr-15, Volume: 308, Issue:5720 Topics: Animals; Brain; Clinical Trials as Topic; Dopamine; Glial Cell Line-Derived Neurotrophic Factor; Glutamic Acid; Hallucinations; Hallucinogens; Humans; Ibogaine; Nerve Growth Factors; Receptors, Nicotinic; Receptors, Opioid; Selective Serotonin Reuptake Inhibitors; Serotonin; Substance-Related Disorders	2005
Quantitation of ibogaine and 12-hydroxyibogamine in human plasma by liquid chromatography with fluorimetric detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Aug-05, Volume: 822, Issue:1-2 Topics: Chromatography, High Pressure Liquid; Drug Stability; Fluorometry; Humans; Ibogaine; Reproducibility of Results; Sensitivity and Specificity	2005
Liquid chromatography-electrospray mass spectrometry determination of ibogaine and noribogaine in human plasma and whole blood. Application to a poisoning involving Tabernanthe iboga root. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, Nov-07, Volume: 843, Issue:2 Topics: Chromatography, Liquid; Drug Stability; Forensic Toxicology; Humans; Ibogaine; Male; Middle Aged; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tabernaemontana	2006
Distribution of ibogaine and noribogaine in a man following a poisoning involving root bark of the Tabernanthe iboga shrub. Journal of analytical toxicology, 2006, Volume: 30, Issue:7 Topics: Chromatography, Liquid; Forensic Medicine; Humans; Ibogaine; Male; Medicine, African Traditional; Middle Aged; Plant Bark; Plant Extracts; Plant Poisoning; Spectrometry, Mass, Electrospray Ionization; Tabernaemontana; Tissue Distribution	2006
Determination of ibogaine and noribogaine in biological fluids and hair by LC-MS/MS after Tabernanthe iboga abuse Iboga alkaloids distribution in a drowning death case. Forensic science international, 2008, Mar-21, Volume: 176, Issue:1 Topics: Adult; Drowning; Gas Chromatography-Mass Spectrometry; Hair; Hallucinogens; Humans; Ibogaine; Male; Molecular Structure; Substance Abuse Detection; Tabernaemontana	2008
Acute toxicity of ibogaine and noribogaine. Medicina (Kaunas, Lithuania), 2008, Volume: 44, Issue:12 Topics: Animals; Behavior, Animal; Excitatory Amino Acid Antagonists; Hallucinogens; Ibogaine; Lethal Dose 50; Mice; Stomach	2008
Noribogaine, but not 18-MC, exhibits similar actions as ibogaine on GDNF expression and ethanol self-administration. Addiction biology, 2010, Volume: 15, Issue:4 Topics: Alcohol Deterrents; Alcohol Drinking; Alcoholism; Animals; Cell Line, Tumor; Conditioning, Operant; Gene Expression; Humans; Ibogaine; Male; Motivation; Rats; Rats, Long-Evans; RNA, Messenger; Self Administration; Ventral Tegmental Area	2010
Effect of Iboga alkaloids on µ-opioid receptor-coupled G protein activation. PloS one, 2013, Volume: 8, Issue:10 Topics: Animals; Autoradiography; Bridged-Ring Compounds; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Female; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); HEK293 Cells; Humans; Ibogaine; Organ Specificity; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Substance Withdrawal Syndrome; Thalamus	2013
A cytosolic relay of heat shock proteins HSP70-1A and HSP90β monitors the folding trajectory of the serotonin transporter. The Journal of biological chemistry, 2014, Oct-17, Volume: 289, Issue:42 Topics: Adenosine Triphosphatases; Cytosol; Endoplasmic Reticulum; Fluorescence Resonance Energy Transfer; Glutathione Transferase; HEK293 Cells; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Ibogaine; Mutation; Protein Folding; Protein Structure, Tertiary; Protein Transport; RNA, Small Interfering; Serotonin Plasma Membrane Transport Proteins	2014
hERG Blockade by Iboga Alkaloids. Cardiovascular toxicology, 2016, Volume: 16, Issue:1 Topics: Alkaloids; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; HEK293 Cells; Humans; Ibogaine; Patch-Clamp Techniques; Plant Extracts; Potassium Channel Blockers; Structure-Activity Relationship; Tabernaemontana	2016
Noribogaine reduces nicotine self-administration in rats. Journal of psychopharmacology (Oxford, England), 2015, Volume: 29, Issue:6 Topics: Animals; Dose-Response Relationship, Drug; Ibogaine; Male; Nicotine; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Self Administration; Smoking Cessation; Tobacco Use Disorder; Varenicline	2015
Noribogaine is a G-protein biased κ-opioid receptor agonist. Neuropharmacology, 2015, Volume: 99 Topics: Analgesics, Opioid; Animals; Arrestins; beta-Arrestins; CHO Cells; Computer Simulation; Cricetulus; Drug Evaluation, Preclinical; Dynorphins; GTP-Binding Proteins; Humans; Ibogaine; Mesencephalon; Mice; Models, Molecular; Morphinans; Rats; Receptors, Opioid, kappa; Receptors, Opioid, mu; Signal Transduction; Substance-Related Disorders	2015
Anti-addiction Drug Ibogaine Prolongs the Action Potential in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Cardiovascular toxicology, 2017, Volume: 17, Issue:2 Topics: Action Potentials; Arrhythmias, Cardiac; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Heart Rate; Humans; Ibogaine; Induced Pluripotent Stem Cells; Myocytes, Cardiac; Neurotransmitter Agents; Patch-Clamp Techniques; Risk Assessment; Substance-Related Disorders; Time Factors	2017
Oral noribogaine shows high brain uptake and anti-withdrawal effects not associated with place preference in rodents. Journal of psychopharmacology (Oxford, England), 2016, Volume: 30, Issue:7 Topics: Administration, Oral; Animals; Brain; Dose-Response Relationship, Drug; Ibogaine; Male; Mice; Morphine; Naloxone; Rats; Rats, Sprague-Dawley; Retrospective Studies; Rodentia; Substance Withdrawal Syndrome	2016
Functional Rescue of a Misfolded The Journal of biological chemistry, 2016, 09-30, Volume: 291, Issue:40 Topics: Animals; Dopamine Plasma Membrane Transport Proteins; Drosophila melanogaster; Drosophila Proteins; Humans; Ibogaine; Molecular Dynamics Simulation; Mutation; Phenotype; Protein Folding; Sleep; Sulfonamides	2016
Anxiolytic-like effects of noribogaine in zebrafish. Behavioural brain research, 2017, 07-14, Volume: 330 Topics: Animals; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Behavior, Animal; Disease Models, Animal; Female; Hallucinogens; Ibogaine; Locomotion; Male; Stress, Physiological; Zebrafish	2017
On the relationship between ibogaine and noribogaine. Clinical toxicology (Philadelphia, Pa.), 2018, Volume: 56, Issue:1 Topics: Arrhythmias, Cardiac; Humans; Ibogaine; Internet; Toxicokinetics	2018
Pharmacochaperoning in a The Journal of biological chemistry, 2017, 11-24, Volume: 292, Issue:47 Topics: Animals; Animals, Genetically Modified; Behavior, Animal; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Drosophila melanogaster; Humans; Ibogaine; Male; Mutation; Parkinsonian Disorders; Sulfonamides; Synaptic Transmission	2017
Coronaridine congeners potentiate GABA Progress in neuro-psychopharmacology & biological psychiatry, 2020, 07-13, Volume: 101 Topics: Animals; Benzodiazepines; Dose-Response Relationship, Drug; GABA-A Receptor Agonists; HEK293 Cells; Humans; Hypnotics and Sedatives; Ibogaine; Locomotion; Male; Maze Learning; Mice; Receptors, GABA-A	2020
A Single Administration of the Atypical Psychedelic Ibogaine or Its Metabolite Noribogaine Induces an Antidepressant-Like Effect in Rats. ACS chemical neuroscience, 2020, 06-03, Volume: 11, Issue:11 Topics: Animals; Antidepressive Agents; Hallucinogens; Ibogaine; Rats; Rodentia	2020
Death due to consumption of ibogaine: case report. Forensic science, medicine, and pathology, 2021, Volume: 17, Issue:1 Topics: Adult; Bridged-Ring Compounds; Fatal Outcome; Hallucinogens; Heroin Dependence; Humans; Ibogaine; Indole Alkaloids; Male	2021