ibogaine has been researched along with naltrexone in 5 studies
| Studies (ibogaine) | Trials (ibogaine) | Recent Studies (post-2010) (ibogaine) | Studies (naltrexone) | Trials (naltrexone) | Recent Studies (post-2010) (naltrexone) |
|---|---|---|---|---|---|
| 445 | 8 | 136 | 8,745 | 1,228 | 2,642 |
| Protein | Taxonomy | ibogaine (IC50) | naltrexone (IC50) |
|---|---|---|---|
| Cytochrome P450 2D6 | Homo sapiens (human) | 1 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.0051 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0063 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.006 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0005 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0005 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.006 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.0319 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0093 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.0377 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.0076 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0004 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berger, SP; Broderick, PA; Hsu, K; Reid, MS; Souza, KH | 1 |
| Glick, SD; Maisonneuve, IM; Pearl, SM | 1 |
| Glick, SD; Maisonneuve, IM; Panchal, V; Taraschenko, OD | 1 |
| Chen, F; Cowen, M; Lawrence, AJ; Overstreet, DH; Rezvani, AH | 1 |
| Willyard, C | 1 |
1 review(s) available for ibogaine and naltrexone
| Article | Year |
|---|---|
Modulation of high alcohol drinking in the inbred Fawn-Hooded (FH/Wjd) rat strain: implications for treatment.
Topics: Alcoholism; Animals; Choice Behavior; Disease Models, Animal; Excitatory Amino Acid Antagonists; Ibogaine; Naltrexone; Narcotics; Phytotherapy; Piperazines; Point Mutation; Pueraria; Rats; Rats, Inbred Strains; Receptors, Opioid; Serotonin; Serotonin Antagonists | 2006 |
4 other study(ies) available for ibogaine and naltrexone
| Article | Year |
|---|---|
Neuropharmacological characterization of local ibogaine effects on dopamine release.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Ibogaine; Male; Microdialysis; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa | 1996 |
Evidence for roles of kappa-opioid and NMDA receptors in the mechanism of action of ibogaine.
Topics: Animals; Corpus Striatum; Dopamine; Female; Ibogaine; Morphine; Motor Activity; N-Methylaspartate; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa; Self Administration; Substance-Related Disorders | 1997 |
Attenuation of morphine withdrawal signs by intracerebral administration of 18-methoxycoronaridine.
Topics: Animals; Brain; Drug Administration Routes; Female; Ibogaine; Locus Coeruleus; Morphine; Morphine Dependence; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 2005 |
Pharmacotherapy: Quest for the quitting pill.
Topics: Animals; Behavior, Addictive; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Clinical Trials as Topic; Cocaine-Related Disorders; Counseling; Dopamine; Drug Discovery; Drug Industry; Humans; Ibogaine; Lobeline; Molecular Targeted Therapy; Naloxone; Naltrexone; Oligopeptides; Opioid-Related Disorders; Pleasure; Rats; Receptors, Nicotinic; Reward; Substance-Related Disorders; Tobacco Use Disorder; Vaccines; Vesicular Monoamine Transport Proteins | 2015 |