Page last updated: 2024-09-05

ibogaine and methadone

ibogaine has been researched along with methadone in 4 studies

Compound Research Comparison

Studies
(ibogaine)
Trials
(ibogaine)
Recent Studies (post-2010)
(ibogaine)
Studies
(methadone)
Trials
(methadone)
Recent Studies (post-2010) (methadone)
445813613,6301,4633,957

Protein Interaction Comparison

ProteinTaxonomyibogaine (IC50)methadone (IC50)
ATP-dependent translocase ABCB1Homo sapiens (human)7.5
Mu-type opioid receptorHomo sapiens (human)0.0041
Delta-type opioid receptorHomo sapiens (human)1.09
Kappa-type opioid receptorHomo sapiens (human)0.512
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)9.7724

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Daley, M; Fuller, BE; McCarty, D; Rieckmann, T; Thomas, CP1
Boucher, A; Carlier, J; Gaillard, Y; Lemeur, C; Mazoyer, C; Péoc'h, M1
Cape, G; Devane, J; Friedhoff, L; Glue, P; Gray, A; Harland, S; Howes, J; Hung, CT; Hung, N; Lam, F; Lockhart, M; Tunnicliff, D; Weis, H1
Cape, G; Crockett, RS; Darpo, B; Devane, J; Friedhoff, L; Glue, P; Harland, S; Howes, J; Hung, CT; Hung, N; Lam, F; Lockhart, M; Tunnicliff, D; Weis, H; Zhou, M1

Trials

2 trial(s) available for ibogaine and methadone

ArticleYear
Switching Opioid-Dependent Patients From Methadone to Morphine: Safety, Tolerability, and Methadone Pharmacokinetics.
    Journal of clinical pharmacology, 2016, Volume: 56, Issue:8

    Topics: Adult; Analgesics, Opioid; Double-Blind Method; Drug Substitution; Female; Headache; Humans; Ibogaine; Male; Methadone; Morphine; Nausea; Opiate Substitution Treatment; Opioid-Related Disorders; Treatment Outcome

2016
Ascending Single-Dose, Double-Blind, Placebo-Controlled Safety Study of Noribogaine in Opioid-Dependent Patients.
    Clinical pharmacology in drug development, 2016, Volume: 5, Issue:6

    Topics: Adult; Area Under Curve; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Female; Heart Rate; Humans; Ibogaine; Long QT Syndrome; Male; Methadone; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Substance Withdrawal Syndrome

2016

Other Studies

2 other study(ies) available for ibogaine and methadone

ArticleYear
Client and counselor attitudes toward the use of medications for treatment of opioid dependence.
    Journal of substance abuse treatment, 2007, Volume: 32, Issue:2

    Topics: Adult; Ambulatory Care; Attitude of Health Personnel; Buprenorphine; Clonidine; Counseling; Culture; Female; Focus Groups; Heroin Dependence; Humans; Ibogaine; Male; Methadone; Middle Aged; Narcotics; Opioid-Related Disorders; Patient Admission; Patient Satisfaction; Peer Group; Psychotropic Drugs; Substance Withdrawal Syndrome; Treatment Outcome

2007
Fatal case of a 27-year-old male after taking iboga in withdrawal treatment: GC-MS/MS determination of ibogaine and ibogamine in iboga roots and postmortem biological material.
    Journal of forensic sciences, 2013, Volume: 58, Issue:6

    Topics: Adult; Bridged-Ring Compounds; Diazepam; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Gastrointestinal Contents; Hallucinogens; Humans; Hypnotics and Sedatives; Ibogaine; Male; Methadone; Molecular Structure; Narcotics; Opiate Substitution Treatment; Plant Roots; Powders; Tabernaemontana

2013