Page last updated: 2024-09-05

ibogaine and 18-methoxycoronaridine

ibogaine has been researched along with 18-methoxycoronaridine in 51 studies

Compound Research Comparison

Studies (ibogaine)	Trials (ibogaine)	Recent Studies (post-2010) (ibogaine)	Studies (18-methoxycoronaridine)	Trials (18-methoxycoronaridine)	Recent Studies (post-2010) (18-methoxycoronaridine)
445	8	136	53	0	17

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (13.73)	18.2507
2000's	25 (49.02)	29.6817
2010's	18 (35.29)	24.3611
2020's	1 (1.96)	2.80

Authors

Authors	Studies
Bandarage, UK; Glick, SD; Kuehne, ME; Maisonneuve, IM; Molinari, HH	1
Bandarage, UK; Glick, SD; Kuehne, ME; Maisonneuve, IM; Overstreet, DH; Rezvani, AH; Yang, Y	1
Bandarage, UK; Glick, SD; Kuehne, ME; Maisonneuve, IM; Mann, GL; Visker, KE	1
Glick, SD; Rho, B	1
Glick, SD; Kuehne, ME; Maisonneuve, IM; Wei, D	1
Bandarage, UK; Fritz, KA; Glick, SD; Kuehne, ME; Maisonneuve, IM; Visker, KE	1
Glick, SD; Maisonneuve, IM	3
Glick, SD; Herr, RJ; King, CH; Maisonneuve, IM; Meckler, H; Trova, MP	1
Blaylock, NA; Glick, SD; Maisonneuve, IM; Mason, R; Mundey, MK; Wilson, VG	1
Glick, SD; Maisonneuve, IM; Szumlinski, KK	4
Dickinson, HA; Glick, SD; Maisonneuve, IM	1
Glick, SD; Maisonneuve, IM; McCafferty, CA; Szumlinski, KK	1
Balogun, MY; Glick, SD; Maisonneuve, IM; Szumlinski, KK	1
Fleck, MW; Glick, SD; Kitchen, BA; Maisonneuve, IM	1
Glick, SD; Kuehne, ME; Maisonneuve, IM; Ramamoorthy, Y; Sellers, EM; Tyndale, RF; Zhang, W	1
de Andrade Costa, D; Delorenzi, JC; Freire-de-Lima, L; Gattass, CR; He, L; Kuehne, ME; Saraiva, EM	1
Vastag, B	2
Bidlack, JM; Fleck, MW; Glick, SD; He, L; Jokiel, PA; Kuehne, ME; Maisonneuve, IM; Pace, CJ	1
Fleck, MW; Glick, SD; He, LW; Jokiel, PA; Kuehne, ME; Maisonneuve, IM; Pace, CJ	1
Bou-Habib, DC; Cirne-Santos, CC; Frugulhetti, IC; Galvão-Castro, B; Kuehne, ME; Saraiva, EM; Silva, EM	1
Glick, SD; Maisonneuve, IM; Panchal, V; Taraschenko, OD	1
Glick, SD; Livi, JM; Maisonneuve, IM; Ramirez, RL	1
Glick, SD; Maisonneuve, IM; Shulan, JM; Taraschenko, OD	1
Glick, SD; Maisonneuve, IM; Rubbinaccio, HY; Taraschenko, OD	1
Glick, SD; Maisonneuve, IM; Sell, EM	1
Glick, SD; McCallum, SE	1
Arias, HR; Feuerbach, D; Glick, SD; Jozwiak, K; Maciejewski, R; Moaddel, R; Rosenberg, A; Targowska-Duda, KM; Wainer, IW	1
Glick, SD; Maisonneuve, IM; Taraschenko, OD	3
Carnicella, S; Glick, SD; He, DY; Ron, D; Yowell, QV	1
Glick, SD; Hathaway, ER; McCallum, SE; Taraschenko, OD; Vincent, MY	1
Glick, SD; Maisonneuve, IM; McCallum, SE; Sell, EM	1
Cowe, MA; Glick, SD; Lewis, SW; McCallum, SE	1
Glick, SD; Polston, JE; Pritchett, CE; Sell, EM	1
Alper, K; Antonio, T; Bornmann, WG; Childers, SR; Dersch, CM; Eshleman, AJ; Janowsky, A; King, C; Kuehne, M; Reith, ME; Rothman, RB; Simon, ER	1
Alper, K; Bai, R; Fowler, SJ; Huang, XP; Liu, N; Priori, SG; Ruan, Y	1
Arias, HR; Feuerbach, D; Jozwiak, K; Targowska-Duda, KM	1
Willyard, C	1
Eggan, BL; McCallum, SE	1
de Moura, FB; McMahon, LR	1
Arias, HR; Lykhmus, O; Skok, M; Uspenska, K	1
Surratt, CK; Wasko, MJ; Witt-Enderby, PA	1
Kamens, HM; Miller, CN; Ruggery, C	1
Anouar, Y; Arias, HR; Chagraoui, A; Chen, Z; Do Rego, JC; Do Rego, JL; Gonzales, EB; Huang, R; Scholze, P	1

Reviews

2 review(s) available for ibogaine and 18-methoxycoronaridine

Article	Year
Mechanisms of action of ibogaine: relevance to putative therapeutic effects and development of a safer iboga alkaloid congener. The Alkaloids. Chemistry and biology, 2001, Volume: 56 Topics: Animals; Behavior, Animal; Cocaine; Humans; Ibogaine; Morphine; Motor Activity; Self Administration	2001
DARK Classics in Chemical Neuroscience: Ibogaine. ACS chemical neuroscience, 2018, 10-17, Volume: 9, Issue:10 Topics: Cardiotoxicity; Hallucinogens; History, 20th Century; History, 21st Century; Humans; Ibogaine; Receptors, Nicotinic; Structure-Activity Relationship; Substance-Related Disorders; Tabernaemontana	2018

Other Studies

49 other study(ies) available for ibogaine and 18-methoxycoronaridine

Article	Year
18-Methoxycoronaridine, a non-toxic iboga alkaloid congener: effects on morphine and cocaine self-administration and on mesolimbic dopamine release in rats. Brain research, 1996, May-06, Volume: 719, Issue:1-2 Topics: Animals; Cerebellum; Cocaine; Dopamine; Female; Ibogaine; Limbic System; Morphine; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Self Administration; Tremor	1996
Attenuation of alcohol consumption by a novel nontoxic ibogaine analogue (18-methoxycoronaridine) in alcohol-preferring rats. Pharmacology, biochemistry, and behavior, 1997, Volume: 58, Issue:2 Topics: Alcohol Drinking; Animals; Dose-Response Relationship, Drug; Ibogaine; Male; Rats	1997
Time-dependent interactions between iboga agents and cocaine. European journal of pharmacology, 1997, Oct-08, Volume: 336, Issue:2-3 Topics: Animals; Cocaine; Drug Interactions; Female; Ibogaine; Motor Activity; Narcotics; Rats; Rats, Sprague-Dawley; Time Factors	1997
Effects of 18-methoxycoronaridine on acute signs of morphine withdrawal in rats. Neuroreport, 1998, May-11, Volume: 9, Issue:7 Topics: Analysis of Variance; Animals; Female; Hallucinogens; Humans; Ibogaine; Morphine Dependence; Rats; Rats, Sprague-Dawley; Stereotyped Behavior; Substance Withdrawal Syndrome; Weight Loss	1998
Acute iboga alkaloid effects on extracellular serotonin (5-HT) levels in nucleus accumbens and striatum in rats. Brain research, 1998, Aug-03, Volume: 800, Issue:2 Topics: Animals; Corpus Striatum; Extracellular Space; Female; Hallucinogens; Ibogaine; Injections, Intraperitoneal; Injections, Intravenous; Microdialysis; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Serotonin; Synaptic Transmission	1998
18-Methoxycoronardine attenuates nicotine-induced dopamine release and nicotine preferences in rats. Psychopharmacology, 1998, Volume: 139, Issue:3 Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Discrimination, Psychological; Dopamine; Homovanillic Acid; Ibogaine; Male; Nicotine; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Self Administration; Smoking	1998
Attenuation of the reinforcing efficacy of morphine by 18-methoxycoronaridine. European journal of pharmacology, 1999, Oct-21, Volume: 383, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Dose-Response Relationship, Drug; Drug Antagonism; Female; Homovanillic Acid; Ibogaine; Microdialysis; Morphine; Narcotics; Nucleus Accumbens; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Self Administration; Time Factors; Visual Cortex	1999
Synthesis of enantiomerically pure (+)- and (-)-18-methoxycoronaridine hydrochloride and their preliminary assessment as anti-addictive agents. Bioorganic & medicinal chemistry letters, 2000, Mar-06, Volume: 10, Issue:5 Topics: Animals; Ibogaine; Morphine; Morphine Dependence; Narcotics; Rats; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Self Administration	2000
Pharmacological comparison of the effect of ibogaine and 18-methoxycoronaridine on isolated smooth muscle from the rat and guinea-pig. British journal of pharmacology, 2000, Volume: 129, Issue:8 Topics: Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Guinea Pigs; Ibogaine; Ileum; Male; Muscle Contraction; Muscle, Smooth; Portal Vein; Rats; Urinary Bladder; Vas Deferens	2000
The potential anti-addictive agent, 18-methoxycoronaridine, blocks the sensitized locomotor and dopamine responses produced by repeated morphine treatment. Brain research, 2000, May-02, Volume: 864, Issue:1 Topics: Animals; Dopamine; Drug Administration Schedule; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Ibogaine; Microdialysis; Morphine; Morphine Dependence; Motor Activity; Narcotics; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reward; Synaptic Transmission; Time Factors	2000
18-MC reduces methamphetamine and nicotine self-administration in rats. Neuroreport, 2000, Jun-26, Volume: 11, Issue:9 Topics: Animals; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Female; Ibogaine; Methamphetamine; Nicotine; Nicotinic Agonists; Rats; Self Administration	2000
Interactions between 18-methoxycoronaridine (18-MC) and cocaine: dissociation of behavioural and neurochemical sensitization. Brain research, 2000, Jul-21, Volume: 871, Issue:2 Topics: Animals; Behavior, Animal; Brain Chemistry; Cocaine; Cocaine-Related Disorders; Dopamine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Female; Ibogaine; Microdialysis; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Stereotyped Behavior	2000
Development of novel medications for drug addiction. The legacy of an African shrub. Annals of the New York Academy of Sciences, 2000, Volume: 909 Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Female; Ibogaine; Morphine; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Self Administration; Substance-Related Disorders	2000
18-Methoxycoronaridine differentially alters the sensitized behavioral and dopaminergic responses to repeated cocaine and morphine administration. Implications for sensitization in the mediation of drug addiction. Annals of the New York Academy of Sciences, 2000, Volume: 909 Topics: Animals; Behavior, Animal; Cocaine-Related Disorders; Dopamine; Humans; Ibogaine; Morphine Dependence	2000
Interactions between iboga agents and methamphetamine sensitization: studies of locomotion and stereotypy in rats. Psychopharmacology, 2000, Volume: 151, Issue:2-3 Topics: Animals; Central Nervous System Stimulants; Female; Hallucinogens; Ibogaine; Methamphetamine; Motor Activity; Rats; Rats, Sprague-Dawley; Stereotyped Behavior	2000
18-Methoxycoronaridine (18-MC) and ibogaine: comparison of antiaddictive efficacy, toxicity, and mechanisms of action. Annals of the New York Academy of Sciences, 2000, Volume: 914 Topics: Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Humans; Ibogaine; In Vitro Techniques; Morphine; Psychopharmacology; Self Administration; Substance Withdrawal Syndrome	2000
Antagonism of alpha 3 beta 4 nicotinic receptors as a strategy to reduce opioid and stimulant self-administration. European journal of pharmacology, 2002, Mar-01, Volume: 438, Issue:1-2 Topics: Acetylcholine; Animals; Cell Line; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Gene Expression; Humans; Ibogaine; Membrane Potentials; Narcotics; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Self Administration	2002
Metabolism of 18-methoxycoronaridine, an ibogaine analog, to 18-hydroxycoronaridine by genetically variable CYP2C19. Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:6 Topics: Animals; Antibodies; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; DNA, Complementary; Enzyme Inhibitors; Genetic Variation; Humans; Ibogaine; In Vitro Techniques; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Rats; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity	2002
In vitro activities of iboga alkaloid congeners coronaridine and 18-methoxycoronaridine against Leishmania amazonensis. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:7 Topics: Alkaloids; Animals; Cells, Cultured; Cytokines; Ibogaine; Leishmania mexicana; Macrophages; Mice; Mice, Inbred BALB C; Nitric Oxide	2002
Addiction treatment strives for legitimacy. JAMA, 2002, Dec-25, Volume: 288, Issue:24 Topics: Animals; Central Nervous System Agents; Clinical Trials as Topic; Drug Evaluation, Preclinical; Humans; Ibogaine; Legislation, Drug; Substance-Related Disorders	2002
Synthesis and biological evaluation of 18-methoxycoronaridine congeners. Potential antiaddiction agents. Journal of medicinal chemistry, 2003, Jun-19, Volume: 46, Issue:13 Topics: Animals; Cell Line; Humans; Ibogaine; Morphine Dependence; Patch-Clamp Techniques; Rats; Receptors, Nicotinic; Receptors, Opioid; Self Administration; Stereoisomerism; Structure-Activity Relationship; Substance-Related Disorders	2003
Anti-addictive actions of an iboga alkaloid congener: a novel mechanism for a novel treatment. Pharmacology, biochemistry, and behavior, 2003, Volume: 75, Issue:3 Topics: Animals; Behavior, Addictive; Brain; Dose-Response Relationship, Drug; Female; Ibogaine; Neural Pathways; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Receptors, Nicotinic; Self Administration	2003
Novel iboga alkaloid congeners block nicotinic receptors and reduce drug self-administration. European journal of pharmacology, 2004, May-25, Volume: 492, Issue:2-3 Topics: Amphetamine-Related Disorders; Animals; Cell Line; Dose-Response Relationship, Drug; Female; Humans; Ibogaine; Morphine Dependence; Nicotinic Antagonists; Patch-Clamp Techniques; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Reward; Self Administration; Tabernaemontana	2004
Anti-HIV-1 activity of the Iboga alkaloid congener 18-methoxycoronaridine. Planta medica, 2004, Volume: 70, Issue:9 Topics: Anti-HIV Agents; Dose-Response Relationship, Drug; HIV-1; Humans; Ibogaine; Leukocytes, Mononuclear; Phytotherapy; Plant Extracts; Tabernaemontana	2004
Addiction research. Ibogaine therapy: a 'vast, uncontrolled experiment'. Science (New York, N.Y.), 2005, Apr-15, Volume: 308, Issue:5720 Topics: Animals; Brain; Clinical Trials as Topic; Dopamine; Glial Cell Line-Derived Neurotrophic Factor; Glutamic Acid; Hallucinations; Hallucinogens; Humans; Ibogaine; Nerve Growth Factors; Receptors, Nicotinic; Receptors, Opioid; Selective Serotonin Reuptake Inhibitors; Serotonin; Substance-Related Disorders	2005
Attenuation of morphine withdrawal signs by intracerebral administration of 18-methoxycoronaridine. European journal of pharmacology, 2005, Nov-21, Volume: 525, Issue:1-3 Topics: Animals; Brain; Drug Administration Routes; Female; Ibogaine; Locus Coeruleus; Morphine; Morphine Dependence; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome	2005
18-Methoxycoronaridine acts in the medial habenula and/or interpeduncular nucleus to decrease morphine self-administration in rats. European journal of pharmacology, 2006, May-10, Volume: 537, Issue:1-3 Topics: Animals; Behavior, Addictive; Conotoxins; Female; Habenula; Ibogaine; Mecamylamine; Mesencephalon; Morphine; Morphine Dependence; Narcotics; Nicotinic Antagonists; Rats; Rats, Long-Evans; Receptors, Nicotinic; Self Administration; Sucrose	2006
18-MC acts in the medial habenula and interpeduncular nucleus to attenuate dopamine sensitization to morphine in the nucleus accumbens. Synapse (New York, N.Y.), 2007, Volume: 61, Issue:7 Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Dopamine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Interactions; Female; Homovanillic Acid; Ibogaine; Mesencephalon; Morphine; Narcotics; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Time Factors	2007
18-methoxycoronaridine: a potential new treatment for obesity in rats? Psychopharmacology, 2008, Volume: 201, Issue:3 Topics: Animal Feed; Animals; Appetite Regulation; Conditioning, Operant; Dopamine; Dose-Response Relationship, Drug; Drinking; Excitatory Amino Acid Antagonists; Feeding Behavior; Female; Food, Formulated; Ibogaine; Injections, Intraperitoneal; Nucleus Accumbens; Obesity; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Saccharin; Sodium Chloride; Solutions; Sucrose; Time Factors; Weight Gain	2008
Brain regions mediating alpha3beta4 nicotinic antagonist effects of 18-MC on methamphetamine and sucrose self-administration. European journal of pharmacology, 2008, Dec-03, Volume: 599, Issue:1-3 Topics: Amygdala; Animals; Behavior, Addictive; Brain; Conotoxins; Drug Administration Routes; Female; Ibogaine; Mecamylamine; Methamphetamine; Nicotinic Antagonists; Rats; Rats, Long-Evans; Receptors, Nicotinic; Self Administration; Sucrose; Tegmentum Mesencephali	2008
18-Methoxycoronaridine blocks acquisition but enhances reinstatement of a cocaine place preference. Neuroscience letters, 2009, Jul-17, Volume: 458, Issue:2 Topics: Analysis of Variance; Animals; Behavior, Addictive; Behavior, Animal; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Extinction, Psychological; Ibogaine; Male; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Time Factors	2009
Interaction of 18-methoxycoronaridine with nicotinic acetylcholine receptors in different conformational states. Biochimica et biophysica acta, 2010, Volume: 1798, Issue:6 Topics: Animals; Binding Sites; Cholinergic Antagonists; Electric Organ; Fish Proteins; Ibogaine; Protein Binding; Protein Structure, Tertiary; Receptors, Cholinergic; Torpedo	2010
18-Methoxycoronaridine, a potential anti-obesity agent, does not produce a conditioned taste aversion in rats. Pharmacology, biochemistry, and behavior, 2010, Volume: 96, Issue:3 Topics: Animals; Anti-Obesity Agents; Avoidance Learning; Conditioning, Operant; Eating; Female; Ibogaine; Lithium Chloride; Rats; Rats, Sprague-Dawley; Sucrose; Taste	2010
Resistance of male Sprague-Dawley rats to sucrose-induced obesity: effects of 18-methoxycoronaridine. Physiology & behavior, 2011, Feb-01, Volume: 102, Issue:2 Topics: Analysis of Variance; Animals; Anti-Obesity Agents; Blood Glucose; Body Weight; Cholesterol; Disease Models, Animal; Drinking; Drug Administration Schedule; Eating; Female; Ibogaine; Male; Obesity; Rats; Rats, Sprague-Dawley; Sucrase; Weight Gain	2011
Noribogaine, but not 18-MC, exhibits similar actions as ibogaine on GDNF expression and ethanol self-administration. Addiction biology, 2010, Volume: 15, Issue:4 Topics: Alcohol Deterrents; Alcohol Drinking; Alcoholism; Animals; Cell Line, Tumor; Conditioning, Operant; Gene Expression; Humans; Ibogaine; Male; Motivation; Rats; Rats, Long-Evans; RNA, Messenger; Self Administration; Ventral Tegmental Area	2010
Effects of 18-methoxycoronaridine on ghrelin-induced increases in sucrose intake and accumbal dopamine overflow in female rats. Psychopharmacology, 2011, Volume: 215, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Adipose Tissue; Animals; Blood Glucose; Cholesterol; Chromatography, High Pressure Liquid; Dopamine; Drinking Behavior; Drug Interactions; Female; Ghrelin; Homovanillic Acid; Ibogaine; Injections, Intraventricular; Microdialysis; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Sucrose; Time Factors; Triglycerides	2011
Sex differences in high fat-induced obesity in rats: Effects of 18-methoxycoronaridine. Physiology & behavior, 2011, Jun-01, Volume: 103, Issue:3-4 Topics: Analysis of Variance; Animals; Body Weight; Dietary Fats; Drug Administration Schedule; Eating; Energy Intake; Female; Ibogaine; Male; Nicotinic Antagonists; Obesity; Rats; Rats, Sprague-Dawley; Sex Characteristics; Weight Gain	2011
Brain regions mediating α3β4 nicotinic antagonist effects of 18-MC on nicotine self-administration. European journal of pharmacology, 2011, Nov-01, Volume: 669, Issue:1-3 Topics: Animals; Behavior, Animal; Brain; Conotoxins; Female; Ibogaine; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Long-Evans; Receptors, Nicotinic; Self Administration	2011
α3β4 nicotinic acetylcholine receptors in the medial habenula modulate the mesolimbic dopaminergic response to acute nicotine in vivo. Neuropharmacology, 2012, Volume: 63, Issue:3 Topics: Animals; Chromatography, High Pressure Liquid; Dextroamphetamine; Dopamine; Dopamine Agents; Extracellular Space; Female; Habenula; Ibogaine; Limbic System; Microdialysis; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic	2012
18-Methoxycoronaridine blocks context-induced reinstatement following cocaine self-administration in rats. Pharmacology, biochemistry, and behavior, 2012, Volume: 103, Issue:1 Topics: Amygdala; Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Classical; Conditioning, Operant; Cues; Dopamine; Drug-Seeking Behavior; Female; Humans; Ibogaine; Music; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Self Administration	2012
Effect of Iboga alkaloids on µ-opioid receptor-coupled G protein activation. PloS one, 2013, Volume: 8, Issue:10 Topics: Animals; Autoradiography; Bridged-Ring Compounds; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Female; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); HEK293 Cells; Humans; Ibogaine; Organ Specificity; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Substance Withdrawal Syndrome; Thalamus	2013
hERG Blockade by Iboga Alkaloids. Cardiovascular toxicology, 2016, Volume: 16, Issue:1 Topics: Alkaloids; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; HEK293 Cells; Humans; Ibogaine; Patch-Clamp Techniques; Plant Extracts; Potassium Channel Blockers; Structure-Activity Relationship; Tabernaemontana	2016
Coronaridine congeners inhibit human α3β4 nicotinic acetylcholine receptors by interacting with luminal and non-luminal sites. The international journal of biochemistry & cell biology, 2015, Volume: 65 Topics: Allosteric Regulation; Binding, Competitive; HEK293 Cells; Humans; Ibogaine; Models, Molecular; Molecular Dynamics Simulation; Nicotinic Antagonists; Radioligand Assay; Receptors, Nicotinic; Structure-Activity Relationship	2015
Pharmacotherapy: Quest for the quitting pill. Nature, 2015, Jun-25, Volume: 522, Issue:7557 Topics: Animals; Behavior, Addictive; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Clinical Trials as Topic; Cocaine-Related Disorders; Counseling; Dopamine; Drug Discovery; Drug Industry; Humans; Ibogaine; Lobeline; Molecular Targeted Therapy; Naloxone; Naltrexone; Oligopeptides; Opioid-Related Disorders; Pleasure; Rats; Receptors, Nicotinic; Reward; Substance-Related Disorders; Tobacco Use Disorder; Vaccines; Vesicular Monoamine Transport Proteins	2015
18-Methoxycoronaridine acts in the medial habenula to attenuate behavioral and neurochemical sensitization to nicotine. Behavioural brain research, 2016, 07-01, Volume: 307 Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Brain Chemistry; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Habenula; Homovanillic Acid; Ibogaine; Locomotion; Microdialysis; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley	2016
The contribution of α4β2 and non-α4β2 nicotinic acetylcholine receptors to the discriminative stimulus effects of nicotine and varenicline in mice. Psychopharmacology, 2017, Volume: 234, Issue:5 Topics: Aconitine; Alkaloids; alpha7 Nicotinic Acetylcholine Receptor; Animals; Azocines; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Dihydro-beta-Erythroidine; Discrimination, Psychological; Dopamine Uptake Inhibitors; Hypnotics and Sedatives; Ibogaine; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Midazolam; Nerve Tissue Proteins; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Quinolizines; Receptors, Nicotinic; Varenicline	2017
Coronaridine congeners modulate mitochondrial α3β4* nicotinic acetylcholine receptors with different potency and through distinct intra-mitochondrial pathways. Neurochemistry international, 2018, Volume: 114 Topics: Animals; Brain; Dose-Response Relationship, Drug; Female; Ibogaine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Liver; Receptors, Nicotinic; Signal Transduction	2018
The α3β4 nicotinic acetylcholine receptor antagonist 18-Methoxycoronaridine decreases binge-like ethanol consumption in adult C57BL/6J mice. Alcohol (Fayetteville, N.Y.), 2019, Volume: 79 Topics: Alcohol Drinking; Animals; Binge Drinking; Ethanol; Female; Hypnotics and Sedatives; Ibogaine; Locomotion; Male; Mice; Mice, Inbred C57BL; Nicotinic Antagonists; Receptors, Nicotinic; Saccharin	2019
Coronaridine congeners potentiate GABA Progress in neuro-psychopharmacology & biological psychiatry, 2020, 07-13, Volume: 101 Topics: Animals; Benzodiazepines; Dose-Response Relationship, Drug; GABA-A Receptor Agonists; HEK293 Cells; Humans; Hypnotics and Sedatives; Ibogaine; Locomotion; Male; Maze Learning; Mice; Receptors, GABA-A	2020