Page last updated: 2024-08-24

hypusine and guanine

hypusine has been researched along with guanine in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (20.00)18.2507
2000's5 (50.00)29.6817
2010's2 (20.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Folk, JE; Lee, YB; Park, MH; Wolff, EC1
Folk, JE; Park, MH; Wolff, EC1
Jansson, BP; Johansson, HE; Malandrin, L1
Bevec, D; Hauber, J; Krätzer, F; Kruse, M; Kuhnt, C; Rosorius, O; Schuler, G; Steinkasserer, A1
Abbruzzese, A; Baldi, A; Caraglia, M; D'Alessandro, AM; Giuberti, G; Marra, M; Tagliaferri, P; Tassone, P; Venuta, S1
Baptista, IL; Cambiaghi, TD; Costa-Neto, CM; Curi, R; Hirabara, SM; Lambertucci, RH; Luchessi, AD; Moriscot, AS; Silveira, LR1
Do, JW; Hong, GE; Kim, KK; Kim, WJ; Kim, YO; Kong, HJ; Lee, CH; Lee, JH; Lee, SJ; Nam, BH1
Balabanov, S; Bokemeyer, C; Braig, M; Hagel, C; Hauber, J; Lamszus, K; Pällmann, N; Preukschas, M; Schulte, A; Sievert, H; Weber, K1
de Almeida, OP; Galvão, FC; Medeiros, AI; Rossetto, Dde B; Rossi, D; Toledo, TR; Valentini, SR; Watanabe, TF; Zanelli, CF1
Blondeau, N; Bourourou, M; Friard, J; Gouix, E; Heurteaux, C; Melis, N; Tauc, M1

Reviews

2 review(s) available for hypusine and guanine

ArticleYear
Is hypusine essential for eukaryotic cell proliferation?
    Trends in biochemical sciences, 1993, Volume: 18, Issue:12

    Topics: Amino Acid Sequence; Animals; Cell Division; Cell Line; Eukaryotic Translation Initiation Factor 5A; Guanine; Humans; Lysine; Molecular Sequence Data; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Protein Precursors; RNA-Binding Proteins; Spermidine

1993
Hypusine modification of the ribosome-binding protein eIF5A, a target for new anti-inflammatory drugs: understanding the action of the inhibitor GC7 on a murine macrophage cell line.
    Current pharmaceutical design, 2014, Volume: 20, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Cytokines; Eukaryotic Translation Initiation Factor 5A; Guanine; Humans; Inflammation; Lysine; Macrophages; Mice; Molecular Targeted Therapy; Nitric Oxide; Peptide Initiation Factors; RNA-Binding Proteins

2014

Other Studies

8 other study(ies) available for hypusine and guanine

ArticleYear
Antiproliferative effects of inhibitors of deoxyhypusine synthase. Inhibition of growth of Chinese hamster ovary cells by guanyl diamines.
    The Journal of biological chemistry, 1994, Nov-11, Volume: 269, Issue:45

    Topics: Animals; Cell Division; Cell Survival; CHO Cells; Cricetinae; Diamines; Dose-Response Relationship, Drug; Guanine; Indicators and Reagents; Kinetics; Lysine; Oxidoreductases Acting on CH-NH Group Donors; Polyamines; Protein Biosynthesis; Putrescine; Spermidine; Spermine; Structure-Activity Relationship

1994
Cell cycle arrest in archaea by the hypusination inhibitor N(1)-guanyl-1,7-diaminoheptane.
    Journal of bacteriology, 2000, Volume: 182, Issue:4

    Topics: Cell Cycle; Enzyme Inhibitors; Escherichia coli; Flow Cytometry; Guanine; Lysine; Sulfolobus acidocaldarius

2000
Inhibition of CD83 cell surface expression during dendritic cell maturation by interference with nuclear export of CD83 mRNA.
    The Journal of experimental medicine, 2000, May-01, Volume: 191, Issue:9

    Topics: Antigen Presentation; Antigens, CD; Biological Transport; CD83 Antigen; Cell Compartmentation; Cell Differentiation; Cell Nucleus; Dendritic Cells; Eukaryotic Translation Initiation Factor 5A; Guanine; Humans; Immunoglobulins; Lymphocyte Activation; Lysine; Membrane Glycoproteins; Peptide Initiation Factors; Protein Processing, Post-Translational; RNA-Binding Proteins; RNA, Messenger; T-Lymphocytes; Up-Regulation

2000
The eukaryotic initiation factor 5A is involved in the regulation of proliferation and apoptosis induced by interferon-alpha and EGF in human cancer cells.
    Journal of biochemistry, 2003, Volume: 133, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Cell Division; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Combinations; Epidermal Growth Factor; Eukaryotic Translation Initiation Factor 5A; Guanine; Humans; Interferon-alpha; KB Cells; Lysine; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Peptide Initiation Factors; Phosphorylation; Protein Processing, Post-Translational; RNA-Binding Proteins

2003
Involvement of eukaryotic translation initiation factor 5A (eIF5A) in skeletal muscle stem cell differentiation.
    Journal of cellular physiology, 2009, Volume: 218, Issue:3

    Topics: Animals; Arginine; Cell Differentiation; Cell Proliferation; Chromatin; Connectin; Eukaryotic Translation Initiation Factor 5A; Gene Expression Regulation; Guanine; Lysine; Male; Muscle Proteins; Muscle, Skeletal; MyoD Protein; Oxidation-Reduction; Peptide Initiation Factors; Protein Biosynthesis; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA-Binding Proteins; RNA, Messenger; Satellite Cells, Skeletal Muscle; Stem Cells

2009
Cloning and characterization of hypusine-containing protein eIF5A from the olive flounder Paralichthys olivaceus.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 2009, Volume: 153, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cloning, Molecular; Eukaryotic Translation Initiation Factor 5A; Flounder; Glycoproteins; Guanine; Kidney; Lysine; Molecular Sequence Data; Novirhabdovirus; Peptide Initiation Factors; Phylogeny; RNA-Binding Proteins; Viral Proteins

2009
Expression of eukaryotic initiation factor 5A and hypusine forming enzymes in glioblastoma patient samples: implications for new targeted therapies.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Apoptosis; Carmustine; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Dacarbazine; Eukaryotic Translation Initiation Factor 5A; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glioblastoma; Guanine; Humans; Lysine; Male; Mixed Function Oxygenases; Molecular Targeted Therapy; Neoplasm Grading; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; RNA-Binding Proteins; Temozolomide

2012
Inhibition of eIF5A hypusination pathway as a new pharmacological target for stroke therapy.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2021, Volume: 41, Issue:5

    Topics: Animals; Behavior, Animal; Cognition; Eukaryotic Translation Initiation Factor 5A; Guanine; Injections, Intraperitoneal; Ischemic Attack, Transient; Lysine; Male; Mice; Mice, Inbred C57BL; Mitochondria; Models, Animal; Neuroprotection; Oxidative Stress; Oxidoreductases Acting on CH-NH Group Donors; Peptide Initiation Factors; Polyamines; Reactive Oxygen Species; RNA-Binding Proteins; Stroke

2021